Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5b/seq/ZK783.4
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Query: ZK783.4 CE18461 status:Partially_confirmed TR:Q23590 protein_id:AAC24421.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
bromodomain Bromodomain 120.5 1.2e-33 1
DDT DDT domain 89.4 2.3e-24 1
MBD Methyl-CpG binding domain 81.9 5e-21 1
PHD PHD-finger 64.2 1.4e-19 2
DAG_PE-bind Phorbol esters/diacylglycerol binding dom 6.7 5.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
MBD 1/1 329 382 .. 1 55 [] 81.9 5e-21
DDT 1/1 524 584 .. 1 63 [] 89.4 2.3e-24
PHD 1/2 1088 1135 .. 1 51 [] 58.8 7.5e-18
DAG_PE-bind 1/1 1154 1174 .. 31 51 .] 6.7 5.1
PHD 2/2 1141 1188 .. 1 51 [] 13.5 0.0037
bromodomain 1/1 1263 1351 .. 1 92 [] 120.5 1.2e-33
Alignments of top-scoring domains:
MBD: domain 1 of 1, from 329 to 382: score 81.9, E = 5e-21
*->drlpLppGWrRetvqRksG.rgagkvDvyYysPvcGKklRSksevir
+rlpL+ GWrR+t++R+++++g+++ Dv Y++P cGKkl+++sev+r
ZK783.4 329 LRLPLQLGWRRQTCVRSIAsAGVKG-DVSYFAP-CGKKLSTYSEVVR 373
YLgangdls<-*
YL +n +++
ZK783.4 374 YLTKNSIHY 382
DDT: domain 1 of 1, from 524 to 584: score 89.4, E = 2.3e-24
*->sesfgdaLmiyEFLrsFGhvLrLsPftlddfiaaLleglldqsdllg
s++f+daLm++EF+++FGhvL+++ +++++++++L++g ld++++++
ZK783.4 524 SQGFADALMVHEFVQNFGHVLGID-LEIAPKLESLCAG-LDGDANHA 568
EvhllLlRallreedd<-*
E++l+L+R+llr + +
ZK783.4 569 EQTLQLTRQLLRLALE 584
PHD: domain 1 of 2, from 1088 to 1135: score 58.8, E = 7.5e-18
*->yCsvCgkvdddaggdllqCDgCdrwfHlaClgppleeppegkWlCpe
C++C++ d g+++l CDgC+ +H++C p ++ +peg+W+C +
ZK783.4 1088 LCQICKSMD---GDEMLVCDGCESGCHMECFRPRMTKVPEGDWFCQR 1131
Ctpk<-*
C+++
ZK783.4 1132 CREE 1135
DAG_PE-bind: domain 1 of 1, from 1154 to 1174: score 6.7, E = 5.1
*->kCsnCglnvHkrChekVptnC<-*
+C+ C + vH++C++ p++
ZK783.4 1154 QCQRCAYHVHQECSQDGPKEA 1174
PHD: domain 2 of 2, from 1141 to 1188: score 13.5, E = 0.0037
*->yCsvCgkvdddaggdllqCDgCdrwfHlaClgpple.eppegkWlCp
+C +C++ + g+l qC C ++H++C + ++++ +++++C
ZK783.4 1141 MCMFCSR---E-TGNLHQCQRCAYHVHQECSQDGPKeAINPETFICG 1183
eCtpk<-*
+C++
ZK783.4 1184 HCQEM 1188
bromodomain: domain 1 of 1, from 1263 to 1351: score 120.5, E = 1.2e-33
*->lnklllkvleeldeqgpralpflfpVlpsklelPDYYeiIkkPMDLk
+nk+l ++++ + +alpfl+pV+p+ +P+Y +iI kPMDLk
ZK783.4 1263 MNKELCQLMLDELVVQANALPFLEPVNPK--LVPGYKMIISKPMDLK 1307
TIkkklkngkYissleeFvaDfnLmfsNAktYNepdsevykdAkk<-*
TI++k ++ Y +++e+F +D++Lmf N++++N + se+ +++++
ZK783.4 1308 TIRQKNEKLIY-ETPEDFAEDIELMFANCRQFNIDHSEIGRAGIS 1351