Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/ZC302.1
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Query:  ZC302.1  CE06573  locus:mre-11 Human MRE11 protein like status:Partially_confirmed TR:Q23255 protein_id:CAA98292.1

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
Mre11_DNA_bind Mre11 DNA-binding presumed domain        413.4   2.1e-120   1
Metallophos    Calcineurin-like phosphoesterase          82.9    6.4e-21   1
Cathelicidins  Cathelicidin                               4.3        3.9   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
Metallophos      1/1     110   349 ..     1   124 []    82.9  6.4e-21
Cathelicidins    1/1     495   507 ..     1    13 [.     4.3      3.9
Mre11_DNA_bind   1/1     355   577 ..     1   241 []   413.4 2.1e-120

Alignments of top-scoring domains:
Metallophos: domain 1 of 1, from 110 to 349: score 82.9, E = 6.4e-21
                   *->mrilvigDlHggfedl............llllela.e.kpdlvlflG
                      ++ilv +D+H+g+++++ + + +  ++ +++l++a+e+k+d++l  G
     ZC302.1   110    IKILVATDIHCGYGENkanihmdavntfEEVLQIAtEqKVDMILLGG 156

                   Dlvdrgppslevllll..................................
                   Dl++ ++ps+ev+ ++++  ++   ++++   +  ++ + + +++  ++
     ZC302.1   157 DLFHENNPSREVQHRVtqllrqyclngnpialeflsdasvnfnqsvfghv 206

                   ..falklkapgpvylvrGNHDfdsgnsvy.....................
                   + + ++l+ + p++ ++GNHD+ sg      +  + ++  + ++++++
     ZC302.1   207 nyYDQNLNVGLPIFTIHGNHDDLSGKGLTaldllhesglvnlfgkhsniq 256

                   ................................welfleef.lllla.lvd
                    +  ++    ++      ++ ++  ++     ++     f ++ +  +++
     ZC302.1   257 efivspillrkgetrlalygigsqrddrlvraFKNNSISFlRPNAGaEDW 306

                   gkillvHgglspd.........leellk.ngvdlvirGHtH.p<-*
                   +++++ H+  ++   +++ ++ l e l +  +dl+i+GH+H++
     ZC302.1   307 FNLFVLHQNRPRRamhrstgnfLPESLIpQFFDLLIWGHEHeC    349

Cathelicidins: domain 1 of 1, from 495 to 507: score 4.3, E = 3.9
                   *->aLsYrEaVlrAvd<-*
                       L+Y+++V+ Avd
     ZC302.1   495    GLRYENVVANAVD    507

Mre11_DNA_bind: domain 1 of 1, from 355 to 577: score 413.4, E = 2.1e-120
                   *->lIdPeenegkgFyVtQPGSSVATSLspGEAlpKHVgLLeIkYGkkFk
                      +++++e++g+gFy++QPGS+VATSL+p+EAl+K+++L++Ik G+kF+
     ZC302.1   355    YVASSEAVGDGFYILQPGSTVATSLTPEEALQKNAFLIKIK-GRKFA 400

                   ltpIPLqTVRPFvmkeiVLadepd....ilglDrpndtdeRYIqkfLieA
                   ++pIPLqTVRP+v++e++L+++p+++++il++Drp++td+RYI++++ieA
     ZC302.1   401 SKPIPLQTVRPMVCDELLLDKIPPgsrpILKTDRPKHTDGRYIDEIAIEA 450

                   kVeemIdeAnaewkekqAdvklgDeprqPpLPLIRLrVDYtggntqdwld
                   k++emI++A+a+        +   +prqP+LPLIRL+V+Y+g+    wl+
     ZC302.1   451 KINEMITTAKAK--------R---RPRQPELPLIRLKVIYDGD----WLN 485

                   yqtfNpiRFgqrFvGrVANpnDvvqFkkkkKpkekkanteveiNftkldd
                   ++++N++R+g r++++VAN++D+v++kk++Kpke+k +te+e+N+t+++d
     ZC302.1   486 ITPANAKRIGLRYENVVANAVDMVFIKKNNKPKEGKLQTENEKNITEMAD 535

                   rdeellaseklnalrVetLVneYletAeknkqLslLperglgeAvqeF<-
                   +++      +++a++++t++n+Y++++++++q+++L+++g+g+A++++
     ZC302.1   536 EMG------QVSATNLQTIINDYFINQPLVDQMTVLKPIGIGRALEQY   577

                   *

     ZC302.1     -   -



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