Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/Y53H1B.1
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Query:  Y53H1B.1  CE22434   cuticlin status:Partially_confirmed TR:Q9U250 protein_id:CAB60411.1

Scores for sequence family classification (score includes all domains):
Model          Description                              Score    E-value  N
--------       -----------                              -----    ------- ---
zona_pellucida Zona pellucida-like domain               216.6    3.7e-61   1
HAMP           HAMP domain                                5.1          8   1
Marek_A        Marek's disease glycoprotein A             4.0        1.1   1

Parsed for domains:
Model          Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------       ------- ----- -----    ----- -----      -----  -------
Marek_A          1/1      96   138 ..   432   474 .]     4.0      1.1
zona_pellucida   1/1      34   280 ..     1   296 []   216.6  3.7e-61
HAMP             1/1     371   396 ..     1    26 [.     5.1        8

Alignments of top-scoring domains:
Marek_A: domain 1 of 1, from 96 to 138: score 4.0, E = 1.1
                   *->PsaRGsPmvlavaavvGlalilrvGdlldalmFiastkKiidl<-*
                      P  RG  m ++v  ++  + i +v   + + +F+  + K++
    Y53H1B.1    96    PEKRGMEMSMTVIISFHSTFITKVDRAYRCTCFYMEADKVVTN    138

zona_pellucida: domain 1 of 1, from 34 to 280: score 216.6, E = 3.7e-61
                   *->qCtedGqmvVvvskdllgfpglilssllllgldpsCqpvpsgsteaf
                      +C ed +++++ ++ ++ f+g i++++ +    ++C +++++s+
    Y53H1B.1    34    DCMED-RVKLSFKTQRP-FHGRIFVKGMV--DKQACVRDFVTSQAKD 76

                   viFqfplndsCGtt.....qvtgdglvYeNtlivSsyevisgppggsItr
                   v+F++ +++ C++++++    +  g+ ++ t+      +is++++  +++
    Y53H1B.1    77 VTFELENGA-CNMRrqrmlGPEKRGMEMSMTV------IISFHST--FIT 117

                   dsdfrlhvsCswdYprtskvsllavdvtwvpfpptpssepgpltGkftls
                   + d ++  +C+  Y++++kv+++ +dv+++p+++ + ++ +pl
    Y53H1B.1   118 KVDRAYRCTCF--YMEADKVVTNKFDVSMLPTTDLIDTARMPL------- 158

                   LrLyngctKGcEmddsysspytsgdypvtkkLGdplyvevsvlqrsdppl
                               +++s+++++ +g++++++k+G+++y+++++   +++++
    Y53H1B.1   159 ------------CTYSVRRDSITGPIVEFAKVGETVYHVWNC---ESDMF 193

                   glfldsCvATpteDpdpnssprydiidngCcldvddkyltsfspvgsssf
                    ++++sC++ ++++      +r +++d+++c  +d+ +l++++++
    Y53H1B.1   194 SMLVHSCFVDDGNG-----DERKPLLDEHGCA-IDPLILPDLTYN----K 233

                   pshylrFqfkaFkFvdsssslspLrslVYihCsvkvCdpscp.dsdlcnk
                   +++++++q+++FkF+d+         + Y++C v+ C+++ + +++++++
    Y53H1B.1   234 DNNVAYAQVNTFKFADK--------VSTYFQCAVSTCMNTEGmCDGKTPP 275

                   aCsfn<-*
                    C ++
    Y53H1B.1   276 RCGPA    280

HAMP: domain 1 of 1, from 371 to 396: score 5.1, E = 8
                   *->lllvlllalllalllalllarrltrP<-*
                      ++l +l+++++++l ++ ++r++t+P
    Y53H1B.1   371    FVLSFLMLTVVTVLTIFTVRRSMTAP    396



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