Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm5/seq/Y32F6A.3
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Query:  Y32F6A.3  CE20204   POLY(A) POLYMERASE (EC 2.7.7.19) (PAP) (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) status:Partially_confirmed TR:Q9U2P3 prot

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
PAP_central  Poly(A) polymerase central domain          364.1   1.5e-105   1
PAP_RNA-bind Poly(A) polymerase predicted RNA binding   243.3    1.2e-71   1
NTP_transf_2 Nucleotidyltransferase domain               38.5    3.3e-09   1
DUF447       Protein of unknown function (DUF447)         4.2        4.9   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
DUF447         1/1      39    56 ..   185   204 .]     4.2      4.9
NTP_transf_2   1/1      84   166 ..    18   122 .]    38.5  3.3e-09
PAP_central    1/1       8   361 ..     1   205 []   364.1 1.5e-105
PAP_RNA-bind   1/1     362   506 ..     1   212 []   243.3  1.2e-71

Alignments of top-scoring domains:
DUF447: domain 1 of 1, from 39 to 56: score 4.2, E = 4.9
                   *->kkvGGereklleeielimrs<-*
                      kk G++++k+  e e++m++
    Y32F6A.3    39    KKFGSYEPKE--ETEQRMEV    56

NTP_transf_2: domain 1 of 1, from 84 to 166: score 38.5, E = 3.3e-09
                   *->avaevylfGSyarGtylpgdSDIDllvvspdpvdr.ef.alffslar
                      a+ +++ fGSy+ G +  g  DID l v+p++ dr++f ++f
    Y32F6A.3    84    AGGKLFTFGSYRLGVHSSG-ADIDTLAVVPRHIDRsDFfTSF----- 124

                   lgkrikevkrleelaeiekeleellglevDlv.vreklecilekkadplv
                              +e+      + el+g+e  +v+v+++++         +v
    Y32F6A.3   125 -----------KEMLNNDPNVTELHGVEEAFVpVMKLKY--------SGV 155

                   rielleervll<-*
                     ++l+ r++l
    Y32F6A.3   156 ELDILFARLAL    166

PAP_central: domain 1 of 1, from 8 to 361: score 364.1, E = 1.5e-105
                RF    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   *->stkqyGvtkpislagpkekdvkltesLieeLkefgsf..........
                      +t+ +Gv++pisla+p++kd+++t+ Lie+Lk+fgs++++++++++
    Y32F6A.3     8    KTPLLGVSQPISLAHPDSKDIAQTTLLIETLKKFGSYepkeeteqrm 54

                RF
                   ..................................................
                   +  ++ ++  ++  ++ +  + +++++ + +++  + ++ + + ++++ +
    Y32F6A.3    55 evlrnlnrlvkewvknvtamkipngegvnaggklftfgsyrlgvhssgad 104

                RF
                   ..................................................
                    ++    +++ ++++  ++ ++  +++++ ++ ++ ++   +  + + ++
    Y32F6A.3   105 idtlavvprhidrsdfftsfkemlnndpnvtelhgveeafvpvmklkysg 154

                RF                                              xxxxx
                   .............................................eilkL
                    + +    +   ++ +++++ ++++  ++ ++++ ++ ++ +  +++lkL
    Y32F6A.3   155 veldilfarlalkevpdtqelsddnllrnldqesvrslngcrvaeQLLKL 204

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   VPnkyevFrltLraiKlWAkrrgiYsNvlGFlgGvaWAiLVAriCQlYPn
                   VP++ ++F++tLraiKlWAk++giYsN++GF+gG++WAiLVAr+CQlYPn
    Y32F6A.3   205 VPRQ-KEFCVTLRAIKLWAKNHGIYSNSMGFFGGITWAILVARACQLYPN 253

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   avpstlvekfFlvfsqWlrhnwpnPVlLkeinsdsieernlqvrvWdprk
                   a+ps+lv+++F++fs+W   +wp+PV+L+e+n+d+ +  +l++ vWdpr+
    Y32F6A.3   254 ASPSRLVHRMFFIFSTW---TWPHPVVLNEMNNDRNDIPTLCELVWDPRR 300

                RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
                   nksDricyhlmPiiTPAyPqqnstynVsestlkvileefkrgleildeie
                   +++Dr  +h+mPiiTPA+P+qnst+nV++st++vi++e++++lei+++i+
    Y32F6A.3   301 KNTDR--FHVMPIITPAFPEQNSTHNVTRSTATVIKNEICEALEICRDIS 348

                RF xxxxxxxxxxxxx
                   lgkaeWskLfeka<-*
                   +gk++W++Lfe++
    Y32F6A.3   349 EGKSKWTALFEEV    361

PAP_RNA-bind: domain 1 of 1, from 362 to 506: score 243.3, E = 1.2e-71
                   *->nFFerYkhYLqitasAagHmAEtaedhLkWsGlVESRlRlLvlkLEr
                      nFF+rYkh++++ ++A+     ++e++L+++G+ ESR+RlLv++LEr
    Y32F6A.3   362    NFFSRYKHFIALIMAAP-----NEEEELNYGGFLESRIRLLVQSLER 403

                   negItlADYRQLRLHpnPkkFedtkecsvdeeaeniangygleksetrls
                   n++I +A       H++P+k++ +++ ++d+++en+
    Y32F6A.3   404 NQDIIIA-------HNDPNKHKPSPNAKFDVNPENK-------------- 432

                   alklAsdekkdeesskdenkavkdssaksgptvfttvwFIGLefkegvks
                                                    ++tvwFIGLef+e+ k+
    Y32F6A.3   433 ---------------------------------RVTVWFIGLEFAEHAKT 449

                   deekklDitypiqeFknickevnrqasnvkglkancqmeidikhVKrkqL
                        lD+t++iq+Fk   ++v+ qasnvkg+++ncq++id+++VKr++L
    Y32F6A.3   450 -----LDLTNEIQRFK---TNVELQASNVKGIGPNCQVQIDMFYVKRNSL 491

                   pqyvfedglkrpkks<-*
                   +q++++ +l+r++++
    Y32F6A.3   492 IQVISAADLRRGRRW    506



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