Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/Y105E8A.9
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Query: Y105E8A.9 CE29847 locus:apt-1 status:Partially_confirmed TR:Q8WQB3 protein_id:CAD21660.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Adaptin_N Adaptin N terminal region 563.8 1.1e-165 1
Alpha_adaptinC2 Adaptin C-terminal domain 46.2 1.5e-13 1
KicB KicB killing factor 2.2 5.4 1
Peptidase_S41B Peptidase family S41B 1.4 6.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Peptidase_S41B 1/1 1 12 [. 397 408 .] 1.4 6.7
Adaptin_N 1/1 45 595 .. 1 629 [] 563.8 1.1e-165
KicB 1/1 721 737 .. 433 449 .] 2.2 5.4
Alpha_adaptinC2 1/1 711 827 .. 1 125 [] 46.2 1.5e-13
Alignments of top-scoring domains:
Peptidase_S41B: domain 1 of 1, from 1 to 12: score 1.4, E = 6.7
*->LdaAiealLkeL<-*
+++A+e++++ +
Y105E8A.9 1 MATAVELAIEKI 12
Adaptin_N: domain 1 of 1, from 45 to 595: score 563.8, E = 1.1e-165
*->ekkeitqelaeilnsfkddKkLdpykkkdavkKliylimlGnedisf
e+ + e a+i++sf+dd d k+++++Kl+y++mlG ++++f
Y105E8A.9 45 ERAVVDRESANIRESFRDD---DSPWKCRNIAKLLYIHMLG-YPAHF 87
lfaevvklvaskkfelKrlgLRrmVYLylkllaeespDGklhlaiLatnt
+++e+ klva ++f++Kr+g YL+++ll++e+++ +++L+tn+
Y105E8A.9 88 GQMECMKLVAHPRFTDKRIG-----YLGAMLLLDERSE----VHMLVTNS 128
ikkDLqspNplirglALrtLscirvpelardlapdikkllvdespnpyVR
+k+DL+ + +++ glAL+tL++i+++e++rdla++++k+++ n+y++
Y105E8A.9 129 LKNDLTCSTQFVSGLALCTLGSICSAEMCRDLANEVEKIIKQ--NNAYLK 176
kkAalailkLyrkdpelvernglvedlkelLsDsnpgVvsaavaaldeic
kkAal+++++ rk+pel+e +++++ +lL ++n+gV+ a+++ +e+c
Y105E8A.9 177 KKAALCAFRIVRKVPELMEV--FIPCTRSLLGEKNHGVLMGATTLVTEMC 224
krnpdllllfrDlklvplLvrfvrlfrklltalsdlnewggnsvpqpfll
+++pd l +f klvp Lvr +l+++l++++s++++++g +++pfl+
Y105E8A.9 225 EKSPDVLNHFK--KLVPNLVR--ILKNLLMSGYSPEHDVTG--ISDPFLQ 268
vkLiklLrlllrkdlvepdpklGlngkdlselltfilqlvntkvelskvq
vk++ r llr l++ d + e +++il++v+t++e+
Y105E8A.9 269 VKIL---R-LLR-VLGKDD-------VRVTEEMNDILAQVATNTETA--- 303
hknvsnavlfvliltisdldsapelivlainkLlvlLlssdpnlrYvaLr
knv+na+l++++lti+ + s+++l+ la+n+L+++Ll++d+n+rYvaL+
Y105E8A.9 304 -KNVGNAILYETVLTIMEIKSESGLRILAVNILGRFLLNTDKNIRYVALN 352
nlnkivmsekhpskehekavqrhrlkiffclstdddisIrlraLdlLykL
+l k v + + avqrhr +++cl+ d+disIr+ra++l ++L
Y105E8A.9 353 TLLKTVH--VDYQ-----AVQRHRNVVVECLK-DPDISIRKRAMELCFAL 394
vdesNvkeivkeLleyveeadndehetfvriavvaiirlaceksnYqypt
++ N+ +++ke l ++e+ad +++ ++++ +a+e+ y +
Y105E8A.9 395 MNRTNIAIMTKEVLIFLETAD-A----EFKSECASRMYIATER----YSP 435
daewcidvLleLLklleggyvvaeaivvqiidiirkyPelreyaVseiit
++ew++d+++ +L+ l+g yv +e+++ +i++i +++l+ yaV +
Y105E8A.9 436 NHEWHLDTMITVLR-LAGKYVPDEVVSC-MIQMISANEQLQSYAV---SQ 480
lLaallesiesmpearaaaiWIlGEygelipdiapvlesepsevtpshid
l+ a + ++ ++ ++++a W +GE+g+l+ + + +s p+ + +++
Y105E8A.9 481 LYHAAQKDAINAQPLLQVAFWTIGEFGDLLLQPTD-VDSTPI--SENDVV 527
llreiaenfslenlevraqlLtalvKLyltkpdifqqakvgeiqpveelv
+ e + ++l +l ++++ +tal+KL++++ + + +++
Y105E8A.9 528 GVFESVLPSALTSLWTKCYGVTALAKLGTRFQSTG------------DRI 565
qsvlqlalnssdnelElRDRAreylrllslad<-*
+ + + lEl++R++e + +l l+d
Y105E8A.9 566 GALVRMNQAHIQ--LELQQRSVEFNVILNLGD 595
KicB: domain 1 of 1, from 721 to 737: score 2.2, E = 5.4
*->aINdfGAkVQAhVIDkY<-*
aIN+ G +VQ VI +
Y105E8A.9 721 AINKGGIEVQLQVIETW 737
Alpha_adaptinC2: domain 1 of 1, from 711 to 827: score 46.2, E = 1.5e-13
*->pkptalpsitayessgLqIgltferrgpgspglgritatftNkssqp
k + +++++a + g++++l+ + +++ +r+ +t N ++ +
Y105E8A.9 711 AKEPTYQPVIAINKGGIEVQLQVIET--WKNEKARLRMTAYNYTPRT 755
vtnfvfqaAVPKslkLqLqpqsgsvlpaggpgaqPAitQvlrvs.npqdg
++n++f+aAV+K++ L p+s++++ ++ tQ +++++ ++
Y105E8A.9 756 LSNYNFFAAVTKTFEIALEPASSPNIDPNEH-----TTQFMTITrKAP-- 798
kkplrlrikltynlngqsvqeqgevsklP<-*
++ r+r k+ y ++g ++ +g v+ +P
Y105E8A.9 799 NTTARMRTKISYIVDGTEQVGEGVVNEFP 827