Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm5/seq/W09B6.1
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: W09B6.1 CE14734 acetyl-CoA carboxylase status:Partially_confirmed TR:Q9GZI3 protein_id:AAG00029.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Carboxyl_trans Carboxyl transferase domain 509.2 3.1e-149 1
CPSase_L_D2 Carbamoyl-phosphate synthase L chain, 314.3 1.4e-90 1
Biotin_carb_C Biotin carboxylase C-terminal domain 127.7 4.1e-36 1
CPSase_L_chain Carbamoyl-phosphate synthase L chain, 80.8 3.9e-21 1
biotin_lipoyl Biotin-requiring enzyme 34.1 4.4e-08 1
thiored Thioredoxin 9.7 0.14 1
nanE Putative N-acetylmannosamine-6-phosph 5.1 3.7 1
Topoisomerase_I Eukaryotic DNA topoisomerase I, catal 4.3 3.3 1
Epimerase NAD dependent epimerase/dehydratase f 3.0 5 1
Filaggrin Filaggrin 2.9 5.9 1
Sec23_trunk Sec23/Sec24 trunk domain 2.6 9.8 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CPSase_L_chain 1/1 47 171 .. 1 129 [] 80.8 3.9e-21
nanE 1/1 238 254 .. 1 17 [. 5.1 3.7
CPSase_L_D2 1/1 173 432 .. 1 262 [] 314.3 1.4e-90
Filaggrin 1/1 479 493 .. 42 55 .] 2.9 5.9
Biotin_carb_C 1/1 441 548 .. 1 118 [] 127.7 4.1e-36
biotin_lipoyl 1/1 687 754 .. 1 75 [] 34.1 4.4e-08
thiored 1/1 1016 1040 .. 1 27 [. 9.7 0.14
Sec23_trunk 1/1 1054 1069 .. 258 280 .] 2.6 9.8
Epimerase 1/1 1645 1658 .. 346 359 .] 3.0 5
Carboxyl_trans 1/1 1413 1967 .. 1 594 [] 509.2 3.1e-149
Topoisomerase_I 1/1 2019 2050 .. 251 284 .] 4.3 3.3
Alignments of top-scoring domains:
CPSase_L_chain: domain 1 of 1, from 47 to 171: score 80.8, E = 3.9e-21
*->didkvLianrGeiaigqarefdysGYEtF.der.iqavaalseedLa
i++ L+a +G++a +++ ++++ tF+++ i +v + +e+ +
W09B6.1 47 PIKRLLVATNGIAAMRCLMTAKKFLHHTFrNDNlIHFVCMTTEDE-I 92
nti...lvnpadatvqtgpglADkvYflpktylnvdkIIeaarpdgvlat
++++++l p++ + + g+ + ++ +nvd+I++ a + v+a+
W09B6.1 93 QSMsesLRMPNITLAESPSGT------NKNNFANVDEILKHAIKYEVDAV 136
hgGyGfLnenaeLaeagvleeygvkflGppaeaIram<-*
++G+G+++en++L++ + ++ +++f+Gppa a+ ++
W09B6.1 137 WAGWGHASENPDLPRRLNDH--NIAFIGPPASAMFSL 171
nanE: domain 1 of 1, from 238 to 254: score 5.1, E = 3.7
*->vsaMAlAAeqAGAvGiR<-*
++M +A+e +G +GiR
W09B6.1 238 FPLMIKASEGGGGKGIR 254
CPSase_L_D2: domain 1 of 1, from 173 to 432: score 314.3, E = 1.4e-90
*->DKisfkaamkeagvptvPssagP.rvDtvhvDkt.lv.VpddlY.kG
DKi++++++++ gvptv +s+++ + ++ + ++v Vp+dl ++
W09B6.1 173 DKIASTIIAQTVGVPTVAWSGSGiTMESIERSRGdFVvVPEDLLeQA 219
lvesaeeAlaaAke..iGYPViIKAAfGgGGkGmriarneeelielfaqA
+v + e+l+a k+++iG+P +IKA++GgGGkG+r + e+++ +f++
W09B6.1 220 CVANYKEGLEALKThnIGFPLMIKASEGGGGKGIRKCTKVEDFKSMFEEV 269
laeapaAFGnpqvlvEKslkgpkhiEyqVlaDahGNcItlcnrECsdqrG
+e+ G+p ++++K ++g++hiE+q+laD++ N+I++ +r+Cs+qr
W09B6.1 270 AQEVQ---GSP-IFLMKCVDGARHIEVQLLADRYENVISVYTRDCSIQR- 314
iRtQksIevAPsqtLtdeerqmlreaAvkiarhvGyvGaGTVeflldp..
R Qk+Ie+AP+ ++++ r+ + e+Av++a+ vGy++aGTVe+l+ p +
W09B6.1 315 -RCQKIIEEAPAIIASSHIRKSMQEDAVRLAKYVGYESAGTVEYLYLPas 363
..dsgefyfIEvNpRLqVehpltekaTGypLakeqakIAlGipLpelkNi
+++ + +yf+E+NpRLqVehp+te+++ + ++++q++IA+G pL+ +k+i
W09B6.1 364 egQEEHYYFLELNPRLQVEHPTTEMVSNISIPAIQLQIAMGLPLHKIKDI 413
vTg.gttAcFEPsLDYvVvKiprwdl<-*
+++ ++ ++++L p+++l
W09B6.1 414 RKLyDLPIDGDSEL-------PDEVL 432
Filaggrin: domain 1 of 1, from 479 to 493: score 2.9, E = 5.9
*->rGSsvSQdsDSE.GH<-*
rGSsv Q DS+ GH
W09B6.1 479 RGSSVHQFADSQfGH 493
Biotin_carb_C: domain 1 of 1, from 441 to 548: score 127.7, E = 4.1e-36
*->EcRInAEDPakgFflPspGritayrsPeeragGpGVRvDsggvyaGy
++RI++E+P+ F +Ps+G++ + ++P ++ + ++ +v+ G+
W09B6.1 441 AARITCENPDDSF-RPSTGKVYEINFP----SSQDAWAYF-SVGRGS 481
eIspyYDSmiaKlivwGedReeAiarMkrALkEfrIrGevkTNIpFLial
++ ++DS++++++++G R+eA + M Lk + Ir ++T + +L++l
W09B6.1 482 SVHQFADSQFGHIFTRGTSRTEAMNTMCSTLKHMTIRSSFPTQVNYLVDL 531
LedpdFlsGneGaFvtTkfld<-*
++d dF+++ ++T++ld
W09B6.1 532 MHDADFINNA----FNTQWLD 548
biotin_lipoyl: domain 1 of 1, from 687 to 754: score 34.1, E = 4.4e-08
*->keiksPmiGesvkegtPvaevlVkvGDkVkaGqvlcevEaMKmemei
++ksP G++ + +++++GD ++G+v+++ E+MKm+ ++
W09B6.1 687 SVLKSPYTGKLLQ-------WKKEDGDWLNVGDVYATAESMKMVFQV 726
pApva.GvvkeilvkeGdtVevGdpLaki<-*
+ +a+G ++ ++ + Gd+++ G +Lak+
W09B6.1 727 EVAKApGRLQRVVNE-GDPIHPGSVLAKL 754
thiored: domain 1 of 1, from 1016 to 1040: score 9.7, E = 0.14
*->ssvvvvltdenFdeevlkaksdkpVLV<-*
++++++ t+++F+++vlk+ +k+++V
W09B6.1 1016 DHFTLTATPKSFNKVVLKG--NKLIVV 1040
Sec23_trunk: domain 1 of 1, from 1054 to 1069: score 2.6, E = 9.8
*->FnatadnDtskFkqdLqRyftrd<-*
F+ ++kF ++L+ +f r+
W09B6.1 1054 FS------SEKFLDCLKTNF-RK 1069
Epimerase: domain 1 of 1, from 1645 to 1658: score 3.0, E = 5
*->eGladTvnWylene<-*
eG+a++++W++ ++
W09B6.1 1645 EGIAKVIRWMSFLP 1658
Carboxyl_trans: domain 1 of 1, from 1413 to 1967: score 509.2, E = 3.1e-149
*->lnkagmgggekavkTkqhpkGkltareRidlLldpGSpFgEledlaf
ln++gm+++ +++ T++ p+G ++++++d++++ GS Fg ed +f
W09B6.1 1413 LNNCGMVAWIMTLYTPEKPRGFDLIVIGNDVTFQSGS-FGTAEDDLF 1458
hrvtefglqadkrglpgdGVvTGsGtidGravevfaqDftvfGGslgpah
++++ + + + +lp++ V+ +sG+++G + + + + + p++
W09B6.1 1459 AAASTYSR---EHKLPRVNVSVNSGARIGLSTKISKLVKLQLENEDKPEQ 1505
gekYlYitramelAikansVatehvveesGaPliginDSGGAedggPRiq
g++Y+Yi+ + i+ e v ee G +++i +GA++ +
W09B6.1 1506 GFEYIYIDGEHKAQIEG-----EVVYEELGNGRLKILAVIGAKNE----K 1546
eGvesLaGyGlIFgansraSgvIPQIslimGpcaGGGaYsPaLtdfvimV
+Gve+L+G+GlI+g+++ra+ ++P+ ++++G+++G+GaY ++L +++++
W09B6.1 1547 IGVENLQGSGLIAGETARAYAEVPTYCYVTGRSVGIGAYTARLAHRIVQH 1596
kdptspmFlTGPdvikkVtGrEevtseeLGGadtHmsksGvaHltaedde
k+ s+++lTG+ ++++++G ++ts++++G++ +m ++Gv+H ++++d+
W09B6.1 1597 KQ--SHLILTGYEALNTLLGKKVYTSNNQLGGPEVMFRNGVTHAVVDNDL 1644
dAlalirkllSyLPkkrsnnmeppPivetgDppdrsveelrtdDLlvsiv
+++a++ +++S+LP +++++++ + gD+ + + ++
W09B6.1 1645 EGIAKVIRWMSFLPTPTEEFPFFSKH---GDDCSA----------RDVVI 1681
Pddp.nkpYDvRevIarivDedgkkfl.GlFDegeFlEvkagyAknvVtG
P+d+++++YDvR++I + ++ ++G+ D +F+E+ +++Ak++V G
W09B6.1 1682 PSDSeQNTYDVRDLIDSKNLSN----QtGICDTMSFDEICGDWAKSIVAG 1727
fARlgGrpVGvvANqprtvEnviPADPAnpdSkEavivlAGQvLdidSad
+ARl G+p+Gvv + r ++PADPA S+ + ++ AGQv+++dSa+
W09B6.1 1728 RARLCGIPIGVVSSEFRNFSTIVPADPAIDGSQVQNTQRAGQVWYPDSAF 1777
KaArFirfCdagfnIPLviLvDvpGFlpGtdqEygGIirhGAkllyAlae
K+A++i++ ++ +n+PL+i++ +GF++G++++y+ ++++GA +++Ala
W09B6.1 1778 KTAEAINDLNK-ENLPLMIIASLRGFSGGQKDMYDMVLKFGAQIVDALAV 1826
AtVPkitvItrmgkayGGAyvVMdskilgaDlveMYfawPtAeiAVMGpe
+ P+i++I+ +g+++GGA+ V dski ++ ++ +++ +++++++p
W09B6.1 1827 YNRPVIVYIPEAGELRGGAWAVLDSKIRPE-FIHLVADE-KSRGGILEPN 1874
GAveIlfrkelaaaamerlDptykdlealLeklseaqedrkqkiaeyeeq
+ v+I+frk + + m+r Dpty +l ++ e+r+q+++ yee+
W09B6.1 1875 AVVGIKFRKPMMMEMMKRSDPTYSKLSSS-----TEPEAREQLEERYEEL 1919
lanpyvaaargfvDdvIdPaetRaklvialallwtkrrrffpwrkhgni<
+ y+ a+++f+D++++ +++ ++v t++rr f ++ +
W09B6.1 1920 -SKTYRNASVEFADAHDRWQRMKSVGVVEHVTSLTNSRRLFSELLRNEL 1967
-*
W09B6.1 - -
[output cut off at A = 10 top alignments]