Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/W04D2.1a
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Query: W04D2.1a CE06539 alpha-actinin status:Partially_confirmed TR:Q23158 protein_id:CAA99941.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
CH Calponin homology (CH) domain 219.2 6e-62 2
spectrin Spectrin repeat 131.7 1.4e-35 4
efhand EF hand 8.9 1.4 2
LTV Low temperature viability protein 6.4 0.97 1
MutS_IV MutS family domain IV 4.5 5.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CH 1/2 38 141 .. 1 106 [] 95.2 6.4e-25
CH 2/2 151 254 .. 1 106 [] 124.1 2.6e-33
LTV 1/1 341 359 .. 493 511 .] 6.4 0.97
spectrin 1/4 305 415 .. 1 108 [] 28.4 2.1e-06
spectrin 2/4 425 530 .. 1 108 [] 83.7 1.1e-21
spectrin 3/4 540 652 .. 1 108 [] 32.3 1.8e-07
MutS_IV 1/1 712 729 .. 1 18 [. 4.5 5.1
spectrin 4/4 696 765 .. 36 108 .] 3.9 13
efhand 1/2 782 792 .. 1 11 [. 0.2 3.8e+02
efhand 2/2 822 850 .. 1 29 [] 8.8 1.6
Alignments of top-scoring domains:
CH: domain 1 of 2, from 38 to 141: score 95.2, E = 6.4e-25
*->sqekellrWinsvlagypgkkstlPippvpvtnfftdwlkDGlaLca
+q+k++++W+ns+l++++ +++ +d++ +Gl L
W04D2.1a 38 QQKKTFTAWCNSHLRKAG----------TSIDTIEEDFR-NGLKLML 73
Llnklr.................eNlnlaldaaekeGlgivlvlldpeDi
Ll+++++++ +++++++ + ++ N+n+al+ +e++G ++ lv +++e+i
W04D2.1a 74 LLEVISgeplpkpdrgkmrfhkiANVNKALEYIESKG-VK-LVSIGAEEI 121
veaegnpdPDeklvltylwqLirrfq<-*
v+ gn k++l+++w++i+rf
W04D2.1a 122 VD--GNV----KMTLGLIWTIILRFA 141
CH: domain 2 of 2, from 151 to 254: score 124.1, E = 2.6e-33
*->sqekellrWinsvlagypgkkstlPippvpvtnfftdwlkDGlaLca
s+++ ll+W+++++a y + v+v+nf +w+ DGla+ca
W04D2.1a 151 SARDGLLLWCQRKTAPYNN---------VNVQNFHNSWK-DGLAFCA 187
Llnklr...............eNlnlaldaaekeGlgivlvlldpeDive
L++++r++ + ++ +++++ +Nlnla+d+aek+ l+i +++ld+eD+
W04D2.1a 188 LIHRHRpdlldysqlhkgdpiHNLNLAFDIAEKH-LDI-PKMLDAEDVSR 235
aegnpdPDeklvltylwqLirrfq<-*
+++ ek+++ty+++++++f+
W04D2.1a 236 --HPD---EKSTMTYVSCFYHAFR 254
LTV: domain 1 of 1, from 341 to 359: score 6.4, E = 0.97
*->KsaleeldkeRrvekrARe<-*
++ le++++ Rr ek+ R+
W04D2.1a 341 QQKLEDYRNYRRREKPPRI 359
spectrin: domain 1 of 4, from 305 to 415: score 28.4, E = 2.1e-06
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeale
++++ + a++l++Wi+ +++l++++ ++l+ +q++l+ + ++
W04D2.1a 305 KMMEDYENLASDLLAWINRWMPWLANRSTDDTLQQAQQKLEDYRNYR 351
aelaaheqdrvkqlnelaqkLieegea...hpdseeikerleeLnerWea
+ ++ +++ + l+ l + L+++ ++++++ + ++ + ++++n++W+
W04D2.1a 352 RREKPPRIEDKGRLETLFNTLQTRLRLsnrPAFLPRDGHLIKDINAAWAG 401
LlelaaeRrqkLee<-*
L++ + +++L+
W04D2.1a 402 LEDSEKGFEEWLLS 415
spectrin: domain 2 of 4, from 425 to 530: score 83.7, E = 1.1e-21
*->lllqqFqrdadelesWisekeallssedygk.DlesvqaLlkkHeal
+l ++F r+++ e+W ke l+s d l ++aL k+Hea+
W04D2.1a 425 HLAEKFRRKCALHEEWAHGKEDALRSNDWRScGLYKIKALRKRHEAF 471
eaelaaheqdrvkqlnelaqkLieegeahpdseeikerleeLnerWeaLl
e +l ah+ drv+q+ ++a++L + +pd i +r+++++++W++L
W04D2.1a 472 ESDLGAHQ-DRVEQIAAIARELNNLR--YPDIGPINARCQAICSQWDRLG 518
elaaeRrqkLee<-*
+l +Rr+ Le+
W04D2.1a 519 QLSSKRRETLED 530
spectrin: domain 3 of 4, from 540 to 652: score 32.3, E = 1.8e-07
*->lllqqFqrdadelesWisekeallssedygkDlesvqaLlkkHeale
l+ F++ a+ +++W++ + + l++ ++ +++ L+ H++++
W04D2.1a 540 SLYLDFAKRAAPFNNWLDGAREDLADLVIVHEMREIEELVNAHDQFK 586
ael..aaheqdrvkqlnelaqkLieegea...hpdseeikerleeLnerW
l++a +e+ ++q++++ + L+++++++++ ++++ ++++++W
W04D2.1a 587 STLgdADREFSSINQIEHEVEHLVTSHGLdreLLRNPYTDLSASDIRRKW 636
eaLlelaaeRrqkLee<-*
+++ + +R +L++
W04D2.1a 637 GEVQNSVPRRDSQLQA 652
MutS_IV: domain 1 of 1, from 712 to 729: score 4.5, E = 5.1
*->gfdeeLDelrdlleelee<-*
g+ ++LDel + ++e++e
W04D2.1a 712 GYKPNLDELERVHQEMQE 729
spectrin: domain 4 of 4, from 696 to 765: score 3.9, E = 13
*->vqaLlkkHealeaelaaheqdrvkqlnelaqkLieegeahpdseeik
++ +++++ +++ + +++ +++++l+ q+++e +++ +
W04D2.1a 696 LEDAIQQLRSIQRNVLGYK-PNLDELERVHQEMQENF--VFENRKSR 739
erleeLnerWeaLlelaaeRrqkLee<-*
+ +e L+ We Ll+ + + ++ e+
W04D2.1a 740 YSMESLRVGWETLLTSINKTINEFEN 765
efhand: domain 1 of 2, from 782 to 792: score 0.2, E = 3.8e+02
*->elkeaFkefDk<-*
e+++ F++fDk
W04D2.1a 782 EFRASFSHFDK 792
efhand: domain 2 of 2, from 822 to 850: score 8.8, E = 1.6
*->elkeaFkefDkDgDGkIsfeEfkaalkkl<-*
el ++ +++D ++ G++ fe f+++++k
W04D2.1a 822 ELHRVLAHVDPNRMGRVPFEAFLDFMTKE 850
[output cut off at A = 10 top alignments]