Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/T22C1.8
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Query: T22C1.8 CE18278 tyrosine specific protein phosphatase status:Partially_confirmed TR:Q22668 protein_id:CAA99930.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Y_phosphatase Protein-tyrosine phosphatase 346.2 3.5e-100 1
DSPc Dual specificity phosphatase, catalytic 12.9 0.024 1
squash Squash family serine protease inhibitor 5.0 0.64 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DSPc 1/1 307 330 .. 102 125 .. 12.9 0.024
Y_phosphatase 1/1 151 376 .. 1 274 [] 346.2 3.5e-100
squash 1/1 455 470 .. 1 16 [. 5.0 0.64
Alignments of top-scoring domains:
DSPc: domain 1 of 1, from 307 to 330: score 12.9, E = 0.024
*->arqkggkVLVHCqAGiSRSAtlii<-*
+r+ g+V VHC AGi R++t+++
T22C1.8 307 VRTASGPVTVHCSAGIGRTGTFVA 330
Y_phosphatase: domain 1 of 1, from 151 to 376: score 346.2, E = 3.5e-100
*->NkeKNRykdilpyDhtRVkLk..egsDYINAnyidgpqsrtlvvykk
N+ KNRykd++++D tRV+L++++++DYI+Any++g
T22C1.8 151 NPTKNRYKDVVCNDITRVILSdgGDGDYIHANYVNG----------L 187
pkayIaTQgPlpnTieDFWrMvweqkvtvIVMLtklvEkgreeeKtCaqY
+ +I+TQg T+ DFWrMv + k+ +IVML++ +E+g+ K CaqY
T22C1.8 188 NAPFILTQGATAATVIDFWRMVVHTKTAYIVMLCEVMEDGK--AK-CAQY 234
WPeeggeeggsltyGditVtlvseekkddddytvRtleltn.gdesknea
+Pe + g+ +t+G t+ + e+ d++++ Rtl ++n ++
T22C1.8 235 YPE---KAGEAMTFGAWTILCSLEDD-KDANIIKRTLSVRNvDN------ 274
kqeklkgetrtVthyhytgWPDhgvPesgpkslldflrkvrksqsqenes
g++++++h+h ++WPD++vP s +++ll++l vr++++
T22C1.8 275 ------GKEHILKHLHTKSWPDRCVPNS-TMALLRMLYIVRTASG----- 312
geaspdsgprSsctgPivVHCSAGiGRTGtfiaidillqqleaegvvidi
P++VHCSAGiGRTGtf+ai+++lq l+ +++ d+
T22C1.8 313 ---------------PVTVHCSAGIGRTGTFVAIEACLQILTDGKEL-DL 346
fdivkelRsqRpgmVQteeQYiFiydaile<-*
+++++ lR++R+g++Q + QY+ + +++++
T22C1.8 347 LGTCRALRNSRAGSIQVDIQYMALVQILIN 376
squash: domain 1 of 1, from 455 to 470: score 5.0, E = 0.64
*->riCPrilmeCkrDsDC<-*
+iC +il+ k+D +C
T22C1.8 455 KICEKILKPIKKDKEC 470