Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/T08B2.7a
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Query: T08B2.7a CE13431 3-hydroxyacyl-CoA dehydrogenase status:Confirmed TR:Q9GYT0 protein_id:AAK21462.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
3HCDH_N 3-hydroxyacyl-CoA dehydrogenase, NAD bin 286.7 2.9e-82 1
ECH Enoyl-CoA hydratase/isomerase family 211.5 1.3e-61 1
3HCDH 3-hydroxyacyl-CoA dehydrogenase, C-termi 151.9 2e-42 2
MORN MORN repeat 7.0 5.6 1
DAO FAD dependent oxidoreductase 6.4 0.88 1
RNA_pol_Rpb6 RNA polymerase Rpb6 6.2 4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ECH 1/1 68 241 .. 1 176 [] 211.5 1.3e-61
RNA_pol_Rpb6 1/1 263 280 .. 39 56 .] 6.2 4
DAO 1/1 379 394 .. 1 16 [. 6.4 0.88
3HCDH_N 1/1 377 559 .. 1 192 [] 286.7 2.9e-82
3HCDH 1/2 561 656 .. 1 106 [] 128.3 1.3e-35
MORN 1/1 644 661 .. 6 23 .] 7.0 5.6
3HCDH 2/2 694 777 .. 6 94 .. 25.5 5.2e-06
Alignments of top-scoring domains:
ECH: domain 1 of 1, from 68 to 241: score 211.5, E = 1.3e-61
*->avikldrPeeavNalsaelltElieAlekleqDpsvravVLtGagpg
av+k+d P+ + N l+++l +E+++ l+kl D s++++V+ +++p+
T08B2.7a 68 AVVKIDLPNTKENVLNKALFAEMKATLDKLQSDESIKSIVVMSGKPN 114
aFsaGaDikemaagfkeplaeqaqfsleaqdlwskledlpkPViAAVNGy
F aGaDi+++ a +++ ++s e q+ + ++e++ kPV+AA+ G+
T08B2.7a 115 SFVAGADIQMIKA--EGTATATETLSREGQEQFFRIEKSQKPVVAAIMGS 162
AlGGGlelALacDyrIAadnAkyvfGlpEvklGiiPGaGGtqrLpRivGv
+ GGGlelALac+yrIA + k+ ++lpEv lG++PGaGGtqrLp+++ v
T08B2.7a 163 CMGGGLELALACHYRIAVNDKKTLLSLPEVMLGLLPGAGGTQRLPKLTTV 212
saAlemiltGrrirAqEAlkmGlVdkVVp<-*
+++l+++ltG++i A+ A+k+G+Vd+V
T08B2.7a 213 QNVLDLTLTGKKIKADKAKKIGIVDRVIQ 241
RNA_pol_Rpb6: domain 1 of 1, from 263 to 280: score 6.2, E = 4
*->dIAlrEiaagkipitirr<-*
+ A++E+a+gk++i +++
T08B2.7a 263 VKAAQELANGKLKINRDK 280
DAO: domain 1 of 1, from 379 to 394: score 6.4, E = 0.88
*->mdvvVIGgGViGlgtA<-*
++++V+G+G G+g+A
T08B2.7a 379 NEIAVVGAGLMGAGIA 394
3HCDH_N: domain 1 of 1, from 377 to 559: score 286.7, E = 2.9e-82
*->akdvkqVaViGaGlMGsGIAqvfAskGfpVvlkDinpkaLdkalkeI
+v+ +aV+GaGlMG+GIA v+ +kG+++vl D+np +++++ +I
T08B2.7a 377 --PVNEIAVVGAGLMGAGIANVTIDKGIRTVLLDANPAGVERGQNQI 421
aksLkklakKgklteaeakdefvaevlsrIssstnlaeevedvDLViEAv
a L+k++k+ k+ + e ++++ +++ ++ ++ ++ +++D ViEAv
T08B2.7a 422 ATHLNKQVKRRKINKLE-----KERIYNHLVPTIDY-SAMKNADVVIEAV 465
vENmdlKkkvFAeLdaickpdtILASNTSsLsiseiAsatkRPervIGmH
+E++ lK+kv +++++++ p tI+ASNTS+L+i +iA+a+ RP++vIGmH
T08B2.7a 466 FEDLQLKHKVIKQIESVVGPNTIIASNTSALPIKDIAAASSRPDKVIGMH 515
FFNPVpvMKLVEVIrgekTSdeTiatvvalskkiGKtpVvVkKDc<-*
+F+PV +M+L+E+I+++ TS+eT+at+ l+ k+GK VvVk Dc
T08B2.7a 516 YFSPVEKMQLLEIITHDGTSKETLATAAQLGLKQGKLVVVVK-DC 559
3HCDH: domain 1 of 2, from 561 to 656: score 128.3, E = 1.3e-35
*->GFvvNRllapylnEAirlveeGvAtpedIDaamrlGlGlPMGPfeLa
GF+v R+l+p+ E +rl++eG ++p+++D+ +++ +G+P+G +La
T08B2.7a 561 GFFVVRCLGPMTAEIMRLLQEG-VDPAELDKLTTK-FGFPVGAATLA 605
DlvGlDvglhvlegqgttsvlaeefgdrprgayaPsplleklveaGrlGr
D+vGlDv+ hv++ l++++g r +g +a +ll +lv+aG+ Gr
T08B2.7a 606 DEVGLDVAEHVAQ------FLGKALGPRLGGGSA--DLLSELVKAGHKGR 647
KtGkGFYdY<-*
KtGkG++ Y
T08B2.7a 648 KTGKGIFVY 656
MORN: domain 1 of 1, from 644 to 661: score 7.0, E = 5.6
*->knGkrhGkGvytwadGdr<-*
++G++ GkG++++ dG +
T08B2.7a 644 HKGRKTGKGIFVYGDGKK 661
3HCDH: domain 2 of 2, from 694 to 777: score 25.5, E = 5.2e-06
*->RllapylnEAirlveeGv.AtpedIDaamrlGlGlP..M.GPfeLaD
Rl +++nEA+ ++eeGv A+p d D a G G+P+ ++GPf+ D
T08B2.7a 694 RLVSRFVNEALLCLEEGVlASPSDGDIASVFGVGFPpfWgGPFRFVD 740
lvGlDvglhvlegqgttsvlaeefgdrprgayaPsplleklveaGr<-*
l+G D + + +e +a +++ ++P+ ll++ + G+
T08B2.7a 741 LYGADKLVKSME------KFAGAYEAV---QFEPCQLLKDHAKSGK 777