Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R107.4a
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Query: R107.4a CE31817 tyrosine-protein kinase status:Confirmed TN:CAA78473 protein_id:CAA78473.3
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
pkinase Protein kinase domain 92.2 1.8e-24 2
ABC1 ABC1 family 4.7 4.5 1
RNA_pol_Rpb4 RNA polymerase Rpb4 4.5 5.3 1
ATE_N Arginine-tRNA-protein transferase, N ter 3.7 9.1 1
Sec8_exocyst Sec8 exocyst complex component specific 3.6 7.2 1
RIO1 RIO1 family 2.7 8.4 1
SCO1-SenC SCO1/SenC 2.1 8.3 1
DUF642 Protein of unknown function, DUF642 2.0 8.2 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ABC1 1/1 35 49 .. 27 43 .. 4.7 4.5
RIO1 1/1 34 49 .. 1 26 [. 2.7 8.4
pkinase 1/2 21 199 .. 1 165 [. 82.1 1.1e-21
pkinase 2/2 229 261 .. 180 244 .. 10.0 0.1
DUF642 1/1 408 420 .. 30 42 .. 2.0 8.2
ATE_N 1/1 423 433 .. 106 116 .] 3.7 9.1
Sec8_exocyst 1/1 456 475 .. 151 170 .] 3.6 7.2
RNA_pol_Rpb4 1/1 563 582 .. 99 119 .] 4.5 5.3
SCO1-SenC 1/1 567 592 .. 1 26 [. 2.1 8.3
Alignments of top-scoring domains:
ABC1: domain 1 of 1, from 35 to 49: score 4.7, E = 4.5
*->VHrAvLkdsyGeeVAVK<-*
V+r+++ + G+ VAVK
R107.4a 35 VYRGRTES--GRLVAVK 49
RIO1: domain 1 of 1, from 34 to 49: score 2.7, E = 8.4
*->nVYhAvsyaedgekdshsvlvevAvK<-*
VY +++ e+g+ vAvK
R107.4a 34 EVYRGRT--ESGRL--------VAVK 49
pkinase: domain 1 of 2, from 21 to 199: score 82.1, E = 1.1e-21
*->yelleklGeGsfGkVykakhkdktgkiVAvKilkkekesikekrflr
+ e +G+G++++Vy+++ +g++VAvK+ k+ + + +
R107.4a 21 LFNDESIGKGAYSEVYRGRTE--SGRLVAVKTAC--KKLEVA-AIGI 62
EiqilkrLs.HpNIvrligvfed.......tddhlylvmEymegGdLfdy
Ei+ilk+L++ NIv+++g+ + + +++ t++ + + mEy+ +L
R107.4a 63 EIEILKKLKgASNIVQYFGSNHTkmapgsvTSETISFAMEYASS-SLEAE 111
lrrng..gplsekeakkialQilrGleYLHsngivHRDLKpeNILlden.
+rr ++++ ls + +++++ + +l+ L +++i HRD+K NILl +
R107.4a 112 MRRPKnhRGLSSNALIDLVVDCSMALSALREHNIAHRDIKHMNILLFPGt 161
.......dgtvKiaDFGLArlle..sssklttfvGTpw<-*
+++++++++ K++D G ++ l+++ss+ + t+vGTp+
R107.4a 162 ptrgrrsTHLFKLCDMGCSKSLSenSSHEMRTLVGTPN 199
pkinase: domain 2 of 2, from 229 to 261: score 10.0, E = 0.1
*->sskvDvWSlGviLyElltggplfpgadlpaftggdevdqliifvlkl
s ++D W+lG++Ly +tg k
R107.4a 229 SEQCDLWALGCTLYFCATG--------------------------KF 249
Pfsdelpktridpleelf<-*
Pf++ +++ + l+
R107.4a 250 PFEH------ERNNKSLY 261
DUF642: domain 1 of 1, from 408 to 420: score 2.0, E = 8.2
*->QGdMiLvVPeGaH<-*
++d++LvVP+++H
R107.4a 408 PDDLYLVVPQTSH 420
ATE_N: domain 1 of 1, from 423 to 433: score 3.7, E = 9.1
*->qkRvLkRnarl<-*
++++L+Rn+++
R107.4a 423 MRKILARNIEF 433
Sec8_exocyst: domain 1 of 1, from 456 to 475: score 3.6, E = 7.2
*->levLkeleELrqvPdkleel<-*
l++L e++E + ++d++ +
R107.4a 456 LSMLTEIDEYLALFDRVSTI 475
RNA_pol_Rpb4: domain 1 of 1, from 563 to 582: score 4.5, E = 5.3
*->RisdeeLieeILdvlskyrkf<-*
R++d +L ++I +++ +y+++
R107.4a 563 RLEDMDL-PGICEEIESYVFY 582
SCO1-SenC: domain 1 of 1, from 567 to 592: score 2.1, E = 8.3
*->ialilgvgallsyLfyrskRlLetsK<-*
+ l ++ ++sy fy ++ L+t+K
R107.4a 567 MDLPGICEEIESYVFYDKQAILSTQK 592