Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm4/seq/R05D3.11
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Query: R05D3.11 CE25069 status:Partially_confirmed SW:P34544 protein_id:AAK21437.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Pre-SET Pre-SET motif 161.1 8.4e-51 1
SET SET domain 130.2 3.8e-35 1
MBD Methyl-CpG binding domain 74.6 5.2e-19 1
pkinase_C Protein kinase C terminal domain 4.3 4.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
pkinase_C 1/1 165 178 .. 55 70 .] 4.3 4.6
MBD 1/1 830 885 .. 1 55 [] 74.6 5.2e-19
Pre-SET 1/1 913 1051 .. 1 124 [] 161.1 8.4e-51
SET 1/1 1077 1307 .. 9 265 .] 130.2 3.8e-35
Alignments of top-scoring domains:
pkinase_C: domain 1 of 1, from 165 to 178: score 4.3, E = 4.6
*->eeFrGFSYvnsPersf<-*
e+F++F++ n P+ ++
R05D3.11 165 EQFKNFEFTN-PN-YL 178
MBD: domain 1 of 1, from 830 to 885: score 74.6, E = 5.2e-19
*->drlpLppGWrRetvqRksG..rgagkvDvyYysPvcGKklRSksevi
++pL++GWrR ++++++G++rga k++++Y+sP cG +l+++s+v
R05D3.11 830 IHTPLLCGWRRIMYTMSTGkkRGAVKKNIIYFSP-CGAALHQISDVS 875
rYLgangdls<-*
+Y++ +++l+
R05D3.11 876 EYIHVTRSLL 885
Pre-SET: domain 1 of 1, from 913 to 1051: score 161.1, E = 8.4e-51
*->DisngkEsvpIplVENeVDldkpiPedFtYIneyiptegviipqseW
D+s g E++pIplV N+VD+d p P + +Y++ +++++++++++s+
R05D3.11 913 DFSLGTEGIPIPLV-NSVDNDEP-P-SLEYSKRRFQYNDQVDISSV- 955
WSleflsGCdCtddkgsCspAdsskCaCarlsgnggaypph.k.ipe...
S++f+sGC+C + +Cs d+skC+C++ls+++++ +ph+++++++++
R05D3.11 956 -SRDFCSGCSCDG---DCS--DASKCECQQLSIEAMKRLPHnLqFDGhde 999
...................egylnnrilvepgplIYECNsrCkCgp.sCk
++++++++ + + ++y+n+ + ++ +++YECN++C+C+++sC+
R05D3.11 1000 lyessekqnkflklfffrvPHYQNRLLSSKVISGLYECNDQCSCHRkSCY 1049
NR<-*
NR
R05D3.11 1050 NR 1051
SET: domain 1 of 1, from 1077 to 1307: score 130.2, E = 3.8e-35
*->legfkt...GwGlrAtedIpkGefiiEYpGelitseeaekreddllg
l++fkt ++GwG+rA+ dIp +fi+ Y+G i++++++ +e
R05D3.11 1077 LQIFKTaqsGWGVRALTDIPQSTFICTYVG-AILTDDLA-DE----- 1116
pkyydddgdksldeYlfdldalfLlrEkleSWkpYiiLPktydsPlfWse
++ +d+ Y+ dld
R05D3.11 1117 -LRNADQ-------YFADLDL----------------------------- 1129
eellLkGTllevdeeelkeykdllaeeievflqlklFpdveteefsyedy
kd
R05D3.11 1130 --------------------KDT--------------------------- 1132
lWaasivSRafsl.....................................
++l++++++++++ + ++++++ +++++++++++++ ++
R05D3.11 1133 ----------VELekgredhetdfgyggdesdyddeegsdgdsgddvmnk 1172
..................................................
++++++++++++++ ++++++++++++++++ ++++++++++ ++++
R05D3.11 1173 mvkrqdssesgeetkrltrqkrkqskksgkggsvekddttprdsmekdni 1222
..................vegvnreeenseeelglviDatrkGNlaRFiN
++++++ + ++ ++ ++ +viDa+ +GNl+RF+N
R05D3.11 1223 eskdepvfnwdkyfepfpL---------------YVIDAKQRGNLGRFLN 1257
HSCsPNcevqvvfvdgedlgtsseeetDAeekaglepgdprivifAlrdI
HSC+PN+ vq+v++d++dl + p++++f+ + +
R05D3.11 1258 HSCDPNVHVQHVMYDTHDL------------------RLPWVAFFTRKYV 1289
kaGeELtydYgydlsnge<-*
kaG+ELt+dY+y + +
R05D3.11 1290 KAGDELTWDYQYTQDQTA 1307