Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/K08E7.3
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Query: K08E7.3 CE06147 locus:let-99 Domain found in Dishevelled, Egl-10, and Pleckstrin status:Partially_confirmed TR:Q21341 protein_id:CAB01
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
DEP Domain found in Dishevelled, Egl-10, and Ple 70.1 4.8e-17 1
E6 Early Protein (E6) 4.6 3.3 1
GlnE Glutamate-ammonia ligase adenylyltransferase 4.5 5.1 1
GNT-I GNT-I family 3.1 4.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DEP 1/1 23 107 .. 1 82 [] 70.1 4.8e-17
GlnE 1/1 208 222 .. 215 229 .] 4.5 5.1
GNT-I 1/1 365 375 .. 455 465 .] 3.1 4.1
E6 1/1 595 604 .. 101 110 .] 4.6 3.3
Alignments of top-scoring domains:
DEP: domain 1 of 1, from 23 to 107: score 70.1, E = 4.8e-17
*->pesgvklkdrkwllkvipncFtGselVdWLmdnlsg.....vidrke
++s+++lk+++ +l + +n+F+G+e+Vd+Lm +++ +++v++r++
K08E7.3 23 FRSNLSLKTNRRGLATAENSFSGKEAVDFLMIEMPRiipnnVPERDK 69
AlhlaqlLlkeGyirhvgdhltgkndhtFldkqtyYrfpd<-*
++++ ++++++++i+ + ++ ++k+ ++F++ ++Y f++
K08E7.3 70 MQKFLEFMMDMNVISEAFPK-KVKQRRPFSE-SRIYLFMK 107
GlnE: domain 1 of 1, from 208 to 222: score 4.5, E = 5.1
*->ddfsliqevreMRrk<-*
+ ++ ++ev eM++k
K08E7.3 208 EEYTEKREVSEMKEK 222
GNT-I: domain 1 of 1, from 365 to 375: score 3.1, E = 4.1
*->rsKvkgYdpsW<-*
+sKv gYd+ W
K08E7.3 365 ASKVDGYDIQW 375
E6: domain 1 of 1, from 595 to 604: score 4.6, E = 3.3
*->grWrGrCrhC<-*
g W+G C C
K08E7.3 595 GLWTGVCSKC 604