Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/K04D7.4
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Query: K04D7.4 CE06093 protein-tyrosine phosphatase status:Partially_confirmed TR:Q21214 protein_id:CAA93513.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Y_phosphatase Protein-tyrosine phosphatase 349.3 4.3e-101 2
fn3 Fibronectin type III domain 107.0 1.9e-29 3
ig Immunoglobulin domain 26.9 8.9e-06 1
DSPc Dual specificity phosphatase, catalytic 7.8 0.66 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ig 1/1 62 132 .. 1 50 [] 26.9 8.9e-06
fn3 1/3 155 243 .. 1 84 [] 51.4 2.2e-13
fn3 2/3 252 338 .. 1 84 [] 22.4 5.2e-05
fn3 3/3 366 443 .. 16 84 .] 33.2 3.8e-08
DSPc 1/1 853 868 .. 107 122 .. 7.8 0.66
Y_phosphatase 1/2 687 917 .. 1 274 [] 341.6 8.4e-99
Y_phosphatase 2/2 992 1012 .. 60 80 .. 8.8 0.16
Alignments of top-scoring domains:
ig: domain 1 of 1, from 62 to 132: score 26.9, E = 8.9e-06
*->GesvtLtCsvsgfgpp.p.vtWlrngk.le.................
+ + +Cs + + + +W+ ++ ++ + +++++ ++++
K04D7.4 62 TQLALVNCSPN---GVtFqNYWKLSKHvVQldiladssrqwwvsdgr 105
....tsslslti.svtpeDsgGtYtCvv<-*
+ + ++l++++vtpeDs GtY+C+
K04D7.4 106 yqliRPFYTLRVsPVTPEDS-GTYRCRL 132
fn3: domain 1 of 3, from 155 to 243: score 51.4, E = 2.2e-13
*->PsaPtnltvtdvtstsltlsWsppt..gngpitgYevtyRqpkngge
P aP+ + ++ t s+tl W++ + ++pi +++v++R +++++
K04D7.4 155 PVAPSSPEIKTFTNRSITLVWTHNAarAHRPILRFSVSVR-TVSDNT 200
wneltvpgtttsytltgLkPgteYevrVqAvnggG....GpeS<-*
+ p+++t++++ +L P+t Y ++V+A n +G+++ Gpe+
K04D7.4 201 RFVMAAPSNATTVIVDNLSPYTLYAFSVRAENSAGssdfGPET 243
fn3: domain 2 of 3, from 252 to 338: score 22.4, E = 5.2e-05
*->P.saPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge
P+ +P+ +++++ts + ++ +pp++ ng++++Y v q +n+
K04D7.4 252 PnRPPQIQKIRNITSECVEVTITPPDeMNGELDKYLVLI-QAVNETI 297
wneltvpgttt.sytltgLkPgteYevrVqAvnggG.GpeS<-*
++ t +++t++ t+ L P t+Y + + A ng G++p
K04D7.4 298 PRKMTFDKPTStPLTICALSPSTDYALAIEADNGFGtSPQA 338
fn3: domain 3 of 3, from 366 to 443: score 33.2, E = 3.8e-08
*->sltlsWsppt..gngpitgYevtyRqpkngge..wneltvpgt....
++t+ W +p+ + ++ +Y + y + kn+ + + +l+v++++ ++
K04D7.4 366 EITVLWPAPPlnATEKVIKYHLYY-KAKNEDQwkIEHLNVSPNgvks 411
.ttsytltgLkPgteYevrVqAvnggG.GpeS<-*
+ y l +L+P+t+Y +rV A + +G+G+ S
K04D7.4 412 kLFKYRLVDLNPNTQYRIRVSASTIKGeGAQS 443
DSPc: domain 1 of 1, from 853 to 868: score 7.8, E = 0.66
*->gkVLVHCqAGiSRSAt<-*
g+V VHC AG+ RS++
K04D7.4 853 GPVVVHCSAGVGRSGS 868
Y_phosphatase: domain 1 of 2, from 687 to 917: score 341.6, E = 8.4e-99
*->NkeKNRykdilpyDhtRVkLk..egsDYINAnyidgpqsrtlvvykk
N KNRy +i + + tR++L ++ g+DYINAny+d+ ++
K04D7.4 687 NSQKNRYNNIGAIEATRIRLNspTGNDYINANYVDS--------CNE 725
pkayIaTQgPlpnTieDFWrMvweqkvtvIVMLtklvEkgreeeKtCaqY
++ayIaTQ+Plp+T+ DFW M+w++++ +IV++t+ vE+g+ K C+qY
K04D7.4 726 RNAYIATQAPLPSTFSDFWSMIWQERSNIIVCITNMVEDGK--RK-CDQY 772
WPeeggeeggsltyGditVtlvseekkddddytvRtleltn.gdesknea
WP+ + ++t+G+++Vtlvse + ++++ R l l+ ++ +
K04D7.4 773 WPS---QQDSPQTFGNYQVTLVSEST--NAHFSHRILDLKIaKAVP---- 813
kqeklkgetrtVthyhytgWPDhgvPesgpkslldflrkvrksqsqenes
+r+V+++h++gWPDhgvP+s + +ll f+++ +s
K04D7.4 814 ------AVERKVHQLHFMGWPDHGVPSS-VFPLLSFVHYTSDIHS----- 851
geaspdsgprSsctgPivVHCSAGiGRTGtfiaidillqqleaegvvidi
g P+vVHCSAG+GR+G +i++d + ++l + ++
K04D7.4 852 ------TG-------PVVVHCSAGVGRSGSYILVDSMRRHLISFRRL-NV 887
fdivkelRsqRpgmVQteeQYiFiydaile<-*
+ + ++R+qR+ +VQt+eQYiF+++ai +
K04D7.4 888 QGHLTHMRRQRAKLVQTLEQYIFCHEAIRQ 917
Y_phosphatase: domain 2 of 2, from 992 to 1012: score 8.8, E = 0.16
*->ieDFWrMvweqkvtvIVMLtk<-*
+eD Wr+ w+qkv++IV L++
K04D7.4 992 CEDLWRLTWQQKVQTIVILNQ 1012