Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F59B8.2
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Query: F59B8.2 CE03436 isocitrate dehydrogenase status:Confirmed TR:Q21032 protein_id:CAA92778.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
isodh Isocitrate/isopropylmalate dehydrogenase 393.7 9.8e-117 1
DUF135 Protein of unknown function DUF135 8.8 0.22 1
Phage_portal Phage portal protein 5.2 2.1 1
ELK ELK domain 4.9 8.2 1
SPX SPX domain 1.2 4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Phage_portal 1/1 68 87 .. 373 392 .] 5.2 2.1
DUF135 1/1 88 109 .. 357 378 .] 8.8 0.22
ELK 1/1 210 231 .. 1 22 [] 4.9 8.2
SPX 1/1 215 236 .. 315 336 .] 1.2 4
isodh 1/1 12 402 .. 7 404 .] 393.7 9.8e-117
Alignments of top-scoring domains:
Phage_portal: domain 1 of 1, from 68 to 87: score 5.2, E = 2.1
*->istavqaGvltpnEvRrllg<-*
++ av++ ++tp+E+R+ ++
F59B8.2 68 YNVAVKCATITPDEARVEEF 87
DUF135: domain 1 of 1, from 88 to 109: score 8.8, E = 0.22
*->tikriYrsttdrIrelLkGglw<-*
++k+ +s ++ Ir++L+G+ +
F59B8.2 88 KLKKMWKSPNGTIRNILGGTVF 109
ELK: domain 1 of 1, from 210 to 231: score 4.9, E = 8.2
*->eLKeeLlrKYsgylssLkeEfl<-*
K+ l+KY g+ ++ E+
F59B8.2 210 STKNTILKKYDGRFKDIFAEIY 231
SPX: domain 1 of 1, from 215 to 236: score 1.2, E = 4
*->IlKKyDKllgsnlrkpylakvv<-*
IlKKyD +++ ++ + y +++
F59B8.2 215 ILKKYDGRFKDIFAEIYPEYEA 236
isodh: domain 1 of 1, from 12 to 402: score 393.7, E = 9.8e-117
*->GDGIGPEvmeaalkVLkavgekaggelefefeeglvGgaaiDetGie
++++G+E+++++++++k+++++++ + ++ + +++G++ +D+t+ +
F59B8.2 12 VEMQGDEMTRIIWDLIKEKLILPY--VDLNVHFFDLGIEHRDATD-D 55
pLPeETleackeaCdavLlGAvgGPkggWDtltpkevRPEnsGLLaLRKe
+++ ++++a +++ +++ ++A+++P+ e R+E+++L++++K+
F59B8.2 56 QVTIDAANATLKY-NVAVKCATITPD---------EARVEEFKLKKMWKS 95
LdGLfANlRPvkvfspslgdaSPlkreiveggvDiviVRELTGGiYfGip
++G+++N++ ++vf++++++++ ++ ++ + + i+i+R++ ++Y +++
F59B8.2 96 PNGTIRNILGGTVFREPIIVKNVPR-LVNTWSKPIIIGRHAHADQYKATD 144
kgikg.gk.klikflk......eel.v..sgnfgeevavdtklYsrdE.i
++ g gk ++ ++ +++++ +e+ ++ +g +v++ +Y++d +i
F59B8.2 145 FVVPGaGKlEIKFVSAdgtqtiQETvFdfKG-----PGVSLSMYNTDDsI 189
eRIarvAFelArkrgprkkVtsvdKaNVLksSrGAFKlWretveevakkn
+ +a+++F++A++r + ++++++K+++Lk+++G +++++++e++ +
F59B8.2 190 RDFAHASFKYALQR--KFPLYLSTKNTILKKYDG---RFKDIFAEIYPE- 233
kkskfeYPdveLeHmlvDnaamqLvknPkqFDfViVTeNlFGDILSDeAS
+ f++ +++eH+l+D++++q++k+ ++fV++++N++GD++SD +
F59B8.2 234 YEAEFKAAGIWYEHRLIDDMVAQAMKSD--GGFVWACKNYDGDVQSDSVA 281
mltGSLGmlPSASlgaepdtsgfalyEPvHGSAPDIAGKgkKG.ETSANP
+++GSLG+++S+ ++++ ++++++E++HG++++++++++KG+ETS+NP
F59B8.2 282 QGYGSLGLMTSVLVCPD---GKTVEAEAAHGTVTRHYRMHQKGqETSTNP 328
iAtILSaAMMLRySlgleeaA.L.dF.daiEaAVlktLeeGGirTgDLgg
iA+I++++++L++++ l+++ L+ F + +Ea +++t e+ G++T+DL+
F59B8.2 329 IASIFAWSRGLAHRATLDKNSaLeTFaNNLEAVCIETMEA-GFLTKDLAI 377
eadGa........kyvsTsemgdav<-*
+ +G + + ++++y++T e+ d++
F59B8.2 378 CVKGGnasavtrtDYLNTFEFLDKL 402