Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/F58A3.2c
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Query:  F58A3.2c  CE29049  locus:egl-15  status:Partially_confirmed SW:Q10656

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
pkinase  Protein kinase domain                          265.9    5.3e-76   1
ig       Immunoglobulin domain                           67.1    6.3e-17   3
Utp14    Utp14 protein                                    4.2        1.6   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
ig         1/3      48   111 ..     1    50 []    17.5   0.0034
ig         2/3     307   369 ..     1    50 []    28.2  3.8e-06
ig         3/3     407   487 ..     1    50 []    21.4  0.00029
Utp14      1/1     579   627 ..     1    55 [.     4.2      1.6
pkinase    1/1     640   932 ..     1   294 []   265.9  5.3e-76

Alignments of top-scoring domains:
ig: domain 1 of 3, from 48 to 111: score 17.5, E = 0.0034
                   *->GesvtLtCsvsgfgpp.p.vtWlrngk.le............tssls
                      G+  ++ C     +  ++ v W+rn+k l +++ ++++ +++++
    F58A3.2c    48    GDEIKFDCQTA-ASKIsAfVEWYRNDKlLKndqidkdkirkdNNRMM 93

                   lti.svtpeDsgGtYtCvv<-*
                   l++++   +D  G  +C+v
    F58A3.2c    94 LHLkNIDVSDQ-GLWSCRV    111

ig: domain 2 of 3, from 307 to 369: score 28.2, E = 3.8e-06
                   *->GesvtLtCsvsgfgpp.p.vtWlrngk.le............tssls
                      G +++L+C+++  g p+p++ W++ngk l +++ ++++ + + +  s
    F58A3.2c   307    GRTLKLNCRAK--GYPePqIIWYKNGKmLKkssarsggyefkFNRWS 351

                   lti.svtpeDsgGtYtCvv<-*
                   l+++++   Ds G++ C++
    F58A3.2c   352 LEVeDAVVADS-GEFHCEA    369

ig: domain 3 of 3, from 407 to 487: score 21.4, E = 0.00029
                   *->GesvtLtCsvsgfgpp.p.vtWlrngk.le.................
                      ++++t+ C v   ++  p++ W r +k  ++ +  +++ ++   + +
    F58A3.2c   407    NDTATFHCKVV--SDLlPhIIWVRINKiNGsysyynnsaeeymfnyt 451

                   .............tsslslti.svtpeDsgGtYtCvv<-*
                   + ++ ++ + ++    ++lti +v+ +D  G+Y C
    F58A3.2c   452 emdtfdkahvhhvGDESTLTIfNVSLDDQ-GIYACLS    487

Utp14: domain 1 of 1, from 579 to 627: score 4.2, E = 1.6
                   *->eSdDeedESdseeeEedsdDdaHqklLqaitsldtvkkikeskrskr
                      +++D+e+      +++++++   q  +  it+   ++k+++  +s+
    F58A3.2c   579    MNEDNEN------SDDEPSPYQIQIIETPITKKEAARKQRKRMNSEN 619

                   kktesyke<-*
                   + + +y +
    F58A3.2c   620 TVLSEYEV    627

pkinase: domain 1 of 1, from 640 to 932: score 265.9, E = 5.3e-76
                   *->yelleklGeGsfGkVykakhkd..ktgkiVAvKilkkekesikekrf
                      + l+  lGeG+fG+V+ka++k +++++  VAvK+lk  +++++ +++
    F58A3.2c   640    LSLVHMLGEGAFGEVWKATYKEteNNEIAVAVKKLKMSAHEKELIDL 686

                   lrEiqilkrLs.HpNIvrligvfedtddhlylvmEymegGdLfdylrrng
                    +E++  k + +H+N++rlig ++   ++ly+v E++ +G L+d+lr+++
    F58A3.2c   687 VSEMETFKVIGeHENVLRLIGCCT-GAGPLYVVVELCKHGNLRDFLRAHR 735

                   ...............................gplsekeakkialQilrGl
                   +++++ ++++++ ++  ++++ +++++ +   +l+ ++++ +a+Q+++G+
    F58A3.2c   736 pkeekakkssqeltdyleprkasdkddieliPNLTQRHLVQFAWQVAQGM 785

                   eYLHsngivHRDLKpeNILldendgtvKiaDFGLArlle...sssklttf
                   ++L s++i+HRDL+++N+L+ +  +++Ki+DFGL+r+++ ++ +  + ++
    F58A3.2c   786 NFLASKKIIHRDLAARNVLVGDG-HVLKISDFGLSRDVHcndYYRLKRGN 834

                   vGTpwYmmAPEvilegrgysskvDvWSlGviLyElltggplfpgadlpaf
                   +  p  +mA E  l ++ y+ ++DvWS+Gv+L+E++t g
    F58A3.2c   835 GRLPIKWMALEA-LDSNVYTVESDVWSYGVLLWEIMTLG----------- 872

                   tggdevdqliifvlklPfsdelpktridpleelfriikrpglrlplpsnc
                                 ++P++       +  + el++ +k+ g+r+++p++c
    F58A3.2c   873 --------------GTPYP-------TIAMPELYANLKE-GYRMEPPHLC 900

                   SeelkdLlkkcLnkDPskRpGsatakeilnhp.wf<-*
                   + e+++L+++c++   ++Rp   ++k i+  ++w+
    F58A3.2c   901 PQEVYHLMCSCWREKLEERP---SFKTIVDYLdWM    932



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