Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/F53E4.1
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Query:  F53E4.1  CE20848   Human host cell factor C1 like protein status:Confirmed TR:O17718 protein_id:CAB04012.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
Kelch    Kelch motif                                    128.3    4.1e-35   6

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Kelch      1/6      13    63 ..     1    45 []    23.2  5.4e-05
Kelch      2/6      92   134 ..     1    41 [.    24.3  2.5e-05
Kelch      3/6     143   190 ..     1    45 []    30.8  3.5e-07
Kelch      4/6     195   250 ..     1    40 [.    18.8  0.00098
Kelch      5/6     262   306 ..     1    42 [.    27.6    3e-06
Kelch      6/6     314   343 ..     1    27 [.    17.6   0.0022

Alignments of top-scoring domains:
Kelch: domain 1 of 6, from 13 to 63: score 23.2, E = 5.4e-05
                   *->pRsgagvvvlggkiYviGGydg......qslnsvevYDpetntWekl
                      +R+++++ ++g +iY +GGy++++ ++ +   +v v+++e+ +W k+
     F53E4.1    13    RRVNHASIAVGSRIYSFGGYCSgevtdaKDPLDVHVLNTENYRWIKM 59

                   psmp<-*
                   ++
     F53E4.1    60 NPGY    63

Kelch: domain 2 of 6, from 92 to 134: score 24.3, E = 2.5e-05
                   *->pRsgagvvvlggkiYviGGydg..qslnsvevYDpetntWekl<-*
                       R+g++vv + gk Yv GG++++  + n    YDpe n W+k+
     F53E4.1    92    QRYGHTVVEYQGKAYVWGGRNDdyGACNLLHEYDPEYNVWKKV    134

Kelch: domain 3 of 6, from 143 to 190: score 30.8, E = 3.5e-07
                   *->pRsgagvvvlggkiYviGGydg...qslnsvevYDpetntWeklpsm
                       R g+++vv +++++v+GGy  + ++++   +v+D  t tW+++ +
     F53E4.1   143    SRDGHTAVVWNNQMFVFGGYEEdaqRFSQETYVFDFATSTWREMHTK 189

                   p<-*
                   +
     F53E4.1   190 N    190

Kelch: domain 4 of 6, from 195 to 250: score 18.8, E = 0.00098
                   *->pRsgagvvvlggkiYviGGydg................qslnsvevY
                       R ++++ v++g +Y++GG+++++++ ++++  ++ ++q+ ++  ++
     F53E4.1   195    WRDFHTASVIDGMMYIFGGRSDesgqvgdehlfhtihdQYDDTLMAL 241

                   DpetntWek<-*
                   ++ t+ W++
     F53E4.1   242 NLATGAWTR    250

Kelch: domain 5 of 6, from 262 to 306: score 27.6, E = 3e-06
                   *->pRsgagvvvlggkiYviGGydg...qslnsvevYDpetntWeklp<-
                       R+++++ v++gk+Y +GGy g+ ++  n  +++Dp+t  W+ ++
     F53E4.1   262    GRRSHSTWVYDGKMYMFGGYLGtinVHYNELYCFDPKTSMWSVIS   306

                   *

     F53E4.1     -   -

Kelch: domain 6 of 6, from 314 to 343: score 17.6, E = 0.0022
                   *->pRsgagvvvlggkiYviGGydg...qslns<-*
                      +R+++++vv +gk+Y +GG  + +  +l++
     F53E4.1   314    ARRRHCSVVSNGKVYLFGGTMPlpcHPLST    343



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