Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F49E2.5a
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Query: F49E2.5a CE31529 status:Confirmed TR:Q20626 protein_id:CAA86428.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
DUF612 Protein of unknown function, DUF612 1544.1 0 8
SUA5 SUA5 domain 10.7 0.081 2
Calcipressin Calcipressin 4.1 4 1
Bro-N BRO family, N-terminal domain 3.7 6.6 1
Rad21_Rec8_N N terminus of Rad21 / Rec8 like protein 3.2 8.1 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Bro-N 1/1 34 44 .. 97 107 .] 3.7 6.6
DUF612 1/8 1 510 [. 1 517 [] 1335.6 0
DUF612 2/8 511 541 .. 441 471 .. 46.1 5e-14
Calcipressin 1/1 578 615 .. 238 275 .] 4.1 4
DUF612 3/8 614 650 .. 437 481 .. 21.8 1.9e-06
Rad21_Rec8_N 1/1 668 693 .. 106 136 .] 3.2 8.1
DUF612 4/8 699 722 .. 493 517 .] -1.9 43
DUF612 5/8 737 815 .. 434 517 .] 158.0 7.5e-49
SUA5 1/2 824 854 .. 1 38 [. 7.6 0.6
DUF612 6/8 816 865 .. 349 390 .. 7.3 0.063
SUA5 2/2 876 897 .. 1 22 [. 7.1 0.85
DUF612 7/8 868 914 .. 349 387 .. 2.3 2.1
DUF612 8/8 972 999 .. 489 517 .] -2.3 61
Alignments of top-scoring domains:
Bro-N: domain 1 of 1, from 34 to 44: score 3.7, E = 6.6
*->FqkWlteevLP<-*
F++Wl+ vLP
F49E2.5a 34 FRQWLLTAVLP 44
DUF612: domain 1 of 8, from 1 to 510: score 1335.6, E = 0
*->mRsPKsvRRPHiRqqLtnRRKnLGRvAKsqRnqFRqWLLtAvLPnsi
mRsPKsvRRPHiRqqLtnRRKnLGRvAKsqRnqFRqWLLtAvLPnsi
F49E2.5a 1 MRSPKSVRRPHIRQQLTNRRKNLGRVAKSQRNQFRQWLLTAVLPNSI 47
nDqRKEAFAsLELtEqPqqvEKvKKsEKKKAqKqiAKDHEAEqKvnAKKA
nDqRKEAFAsLELtEqPqqvEKvKKsEKKKAqKqiAKDHEAEqKvnAKKA
F49E2.5a 48 NDQRKEAFASLELTEQPQQVEKVKKSEKKKAQKQIAKDHEAEQKVNAKKA 97
AEKEARRAEAEAKKRAAqEEEHKqWKAEqERiqKEqEKKEADLKKLqAEK
AEKEARRAEAEAKKRAAqEEEHKqWKAEqERiqKEqEKKEADLKKLqAEK
F49E2.5a 98 AEKEARRAEAEAKKRAAQEEEHKQWKAEQERIQKEQEKKEADLKKLQAEK 147
KKEKAvKAEKAEKAEKtKKAstPAPvEEEivvKKvAnDRsAAPAPEPKtP
KKEKAvKAEKAEKAEKtKKAstPAPvEEEivvKKvAnDRsAAPAPEPKtP
F49E2.5a 148 KKEKAVKAEKAEKAEKTKKASTPAPVEEEIVVKKVANDRSAAPAPEPKTP 197
tntPAEPAEqvqEitGKKnKKnKKKsEsEAtAAPAsvEqvvEqPKvvtEE
tntPAEPAEqvqEitGKKnKKnKKKsEsEAtAAPAsvEqvvEqPKvvtEE
F49E2.5a 198 TNTPAEPAEQVQEITGKKNKKNKKKSESEATAAPASVEQVVEQPKVVTEE 247
PHqqAAPqEKKnKKnKRKsEsEnvPAAsEtPvEPvvEttPPAsEnqKKnK
PHqqAAPqEKKnKKnKRKsEsEnvPAAsEtPvEPvvEttPPAsEnqKKnK
F49E2.5a 248 PHQQAAPQEKKNKKNKRKSESENVPAASETPVEPVVETTPPASENQKKNK 297
KDKKKsEsEKvvEEPvqAEAPKsKKPtADDnmDFLDFvtAKEEPKDEPAE
KDKKKsEsEKvvEEPvqAEAPKsKKPtADDnmDFLDFvtAKEEPKDEPAE
F49E2.5a 298 KDKKKSESEKVVEEPVQAEAPKSKKPTADDNMDFLDFVTAKEEPKDEPAE 347
tPAAPvEEvvEnvvEnvvEKsttPPAtEnKKKnKKDKKKsEsEKvtEqPv
tPAAPvEEvvEnvvEnvvEKsttPPAtEnKKKnKKDKKKsEsEKvtEqPv
F49E2.5a 348 TPAAPVEEVVENVVENVVEKSTTPPATENKKKNKKDKKKSESEKVTEQPV 397
EsAPAPPqvEqvvEktppasenkkknkkdkkksesekavEkPvqaAPvsK
EsAPAPPqvEqvvE+tppasenkkknkkdkkksesekavE+PvqaAP+sK
F49E2.5a 398 ESAPAPPQVEQVVETTPPASENKKKNKKDKKKSESEKAVEEPVQAAPSSK 447
KPtADDsmDFLDFvtAKPeksEvveehieapaivEvvkveeetAvaaenk
KPtADDsmDFLDFvtAKP++sEv+ a+vEv+kv+e+tAv++en+
F49E2.5a 448 KPTADDSMDFLDFVTAKPDRSEVA-------APVEVAKVDESTAVTSENR 490
KKnKKdKkKkesEkaveEsv<-*
KKnKKdKkK+esEkaveE+v
F49E2.5a 491 KKNKKDKKKSESEKAVEEPV 510
DUF612: domain 2 of 8, from 511 to 541: score 46.1, E = 5e-14
*->qaAPvsKKPtADDsmDFLDFvtAKPeksEvv<-*
qaAP sKKPtADDsmDFLDFvtAK e+ E v
F49E2.5a 511 QAAPTSKKPTADDSMDFLDFVTAKEERVEEV 541
Calcipressin: domain 1 of 1, from 578 to 615: score 4.1, E = 4
*->vceteidgeeaddlidqSgvsdtprpkakivqTarPpr<-*
++ ++i + ad+ i q +vs ++ +++++v+ P+
F49E2.5a 578 MGFSDIVTPKADEVITQDPVSAKQEVLPEHVPSEIPEE 615
DUF612: domain 3 of 8, from 614 to 650: score 21.8, E = 1.9e-06
*->EkPvqaAPvsKKPtADDsmDFLDFvtAKPeksEvveehieapaiv<-
E+Pv vsKKPtA DsmDFLDFvt K e eapa+v
F49E2.5a 614 EEPV---AVSKKPTA-DSMDFLDFVTPKTEAESTS----EAPAPV 650
*
F49E2.5a - -
Rad21_Rec8_N: domain 1 of 1, from 668 to 693: score 3.2, E = 8.1
*->kkaFrsgqkdfevdlPeenrtarinsnltlP<-*
+ a+++g ++ P++++t ++ns + l+
F49E2.5a 668 HVADVTGN----TLSPSQHSTPSPNS-VLLN 693
DUF612: domain 4 of 8, from 699 to 722: score -1.9, E = 43
*->aaenkKKnKKdKkKkesEkaveEsv<-*
++ k KK+Kk+ +sE +E+
F49E2.5a 699 SSKRKHHHKKNKKRTDSEM-SQEPS 722
DUF612: domain 5 of 8, from 737 to 815: score 158.0, E = 7.5e-49
*->kavEkPvqaAPvsKKPtADDsmDFLDFvtAKPeksEvveehieapai
k vEkPv APvsKKPtADD+mDFLDFvtAKPek+E+veehieap+i
F49E2.5a 737 KKVEKPV--APVSKKPTADDNMDFLDFVTAKPEKTESVEEHIEAPMI 781
vEvvkveeetAvaaenkKKnKKdKkKkesEkaveEsv<-*
vE+v++e+etA+aa++kKKnKK+K+Kk+sE+ Es+
F49E2.5a 782 VEPVHAENETAAAAGGKKKNKKNKNKKNSES---EST 815
SUA5: domain 1 of 2, from 824 to 854: score 7.6, E = 0.6
*->ITvEeiekvlGekilvkvveakkGleeaevpkaPGMKY<-*
+T+E +e+v+++k++++ ++a + aPG K+
F49E2.5a 824 VTPEIVEEVFEKKTITPSTAA-------AAAPAPGSKK 854
DUF612: domain 6 of 8, from 816 to 865: score 7.3, E = 0.063
*->PAA.PvEEvvEnvvEnvvEKsttPPAtEnK.......KKnKKDKKKs
PAA+Pv Ev +vE v EK t P t + +++KKnKK KK s
F49E2.5a 816 PAAePVKEVTPEIVEEVFEKKTITPSTAAAaapapgsKKNKKNKKNS 862
EsE<-*
EsE
F49E2.5a 863 ESE 865
[output cut off at A = 10 top alignments]