Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F46B3.5
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Query: F46B3.5 CE18688 locus:grd-2 Hint module status:Partially_confirmed TR:Q9XV14 protein_id:CAB04405.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
DUF398 Domain of unknown function (DUF398) 383.2 2.7e-111 4
Hint Hint module 208.3 9.9e-64 1
Adeno_E1B_19K Adenovirus E1B 19K protein / small t-an 6.9 0.93 1
RIO1 RIO1 family 2.9 7.4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DUF398 1/4 2 41 .. 47 86 .] 40.0 2.1e-09
DUF398 2/4 198 283 .. 1 86 [] 115.8 8.4e-31
DUF398 3/4 347 432 .. 1 86 [] 125.0 1.4e-33
RIO1 1/1 481 503 .. 44 66 .. 2.9 7.4
DUF398 4/4 462 547 .. 1 86 [] 115.0 1.4e-30
Adeno_E1B_19K 1/1 736 755 .. 41 60 .. 6.9 0.93
Hint 1/1 654 840 .. 10 210 .. 208.3 9.9e-64
Alignments of top-scoring domains:
DUF398: domain 1 of 4, from 2 to 41: score 40.0, E = 2.1e-09
*->eFggsFeVICsegdFsyvtntdgdlyCkvekdgvtClafk<-*
eF+ sFe+I+s+ +F+++++++g + C v+k g++ l+++
F46B3.5 2 EFHSSFETIVSKTNFAISSHYHGPHTCRVHKKGHYLLVYE 41
DUF398: domain 2 of 4, from 198 to 283: score 115.8, E = 8.4e-31
*->sddnkCndeeLrkimeenideakaspdfgpddlseskraIqkaaeke
+d+nkC+d +L+++m ++++++++sp+fgp+++++++ +q +++++
F46B3.5 198 RDGNKCCDARLAATMRDAMRQMATSPEFGPGKEGIVAAELQQSVQTR 244
FggsFeVICsegdFsyvtntdgdlyCkvekdgvtClafk<-*
F+ s+e+I+s++dF+ +t+t+g+++Ck+++ ++ +la++
F46B3.5 245 FKKSYEIIVSRSDFVATTYTAGEKFCKFKTKNFVILAYV 283
DUF398: domain 3 of 4, from 347 to 432: score 125.0, E = 1.4e-33
*->sddnkCndeeLrkimeenideakaspdfgpddlseskraIqkaaeke
++++kC++++L++ m++++d++kasp+f++++++++++aIq+++e++
F46B3.5 347 RTGSKCCNLRLFNAMKDGYDRHKASPNFDRYNIRNISKAIQWSVEEV 393
FggsFeVICsegdFsyvtntdgdlyCkvekdgvtClafk<-*
F++s eV++s +dF+y+tn +++++Ck+++d ++ +++
F46B3.5 394 FQHSAEVFVSLDDFAYATNEKNEESCKYRVDKYYVYVYT 432
RIO1: domain 1 of 1, from 481 to 503: score 2.9, E = 7.4
*->gdfRFrdrksktswrylvrlWAe<-*
+++R+ d ++k++ ryl+++ ++
F46B3.5 481 DEARYSDSYHKHDTRYLAKMITR 503
DUF398: domain 4 of 4, from 462 to 547: score 115.0, E = 1.4e-30
*->sddnkCndeeLrkimeenideakaspdfgpddlseskraIqkaaeke
d+ C+++ L++ +++ dea++s++++++d++ ++++I++a++++
F46B3.5 462 LDGTACCNSGLQYEINRILDEARYSDSYHKHDTRYLAKMITRAVQRR 508
FggsFeVICsegdFsyvtntdgdlyCkvekdgvtClafk<-*
F+++Fe+I++e+dFs++tn++++++Ck++ +g+++l+++
F46B3.5 509 FNTTFETIVAEADFSWSTNKFTGRMCKIDHEGYNALTYQ 547
Adeno_E1B_19K: domain 1 of 1, from 736 to 755: score 6.9, E = 0.93
*->grikedYeeeFeniLpecpg<-*
+r+k +++eF++iLpe+++
F46B3.5 736 YRTKCNESSEFLKILPENHE 755
Hint: domain 1 of 1, from 654 to 840: score 208.3, E = 9.9e-64
*->laplGvqsGGCFPGdAtVtledGgrKplkdLkpGDrVLAaDeagGrl
+a G+ GGCF+ d++Vt+++G+ K+++++++GD+VL+a ++
F46B3.5 654 FAGGGGGGGGCFSSDTLVTTPSGK-KRMDEIDVGDYVLTANRV--KT 697
vySdvLlFLDRepeqravFyvIeTedgpekltLTpaHLlFvadcsvnkst
+++v+l+++Re+e+ +F +I+Te+g +l LTp H++++++c+ ++
F46B3.5 698 HFTPVTLWIHRESEKLEEFLTITTERG-STLQLTPLHFMYRTKCN---ES 743
PeyikSsgsmgpagfravFAsrvrpGdcvlvadkekggklrpvkVvrvsr
e+ k +p + +a+ As +++Gdcv ++++ +k+r+ k+ +r
F46B3.5 744 SEFLK----ILPENHEAILASYLEIGDCVILTEN---TKFRQEKINQTTR 786
eeatGiYAPLTahGTivVndVlASCYAvIeshsLAhwaFaPylRLlssLl
+tGiY+PLT++G+i+Vnd+lASCY++++ + L++++F+ RL+++ l
F46B3.5 787 GLKTGIYSPLTKNGRIIVNDMLASCYSEVQANVLQTTYFWVFNRLRQKVL 836
sflg<-*
+++g
F46B3.5 837 NLFG 840