Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F45H11.4
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Query: F45H11.4 CE17833 locus:mgl-2 metabotropic glutamate receptor status:Partially_confirmed TR:Q93564 protein_id:CAB01711.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
7tm_3 7 transmembrane receptor (metabotropic 401.9 6.1e-117 1
bZIP_Maf bZIP Maf transcription factor 375.3 6.4e-109 1
ANF_receptor Receptor family ligand binding region 347.4 1.6e-100 1
PSI_PSAK Photosystem I psaG / psaK 8.2 1.1 1
UPAR_LY6 u-PAR/Ly-6 domain 7.4 6.4 1
VSP Giardia variant-specific surface prote 4.7 1.6 1
Ribosomal_L21p Ribosomal prokaryotic L21 protein 4.1 3.8 2
Nitrophorin Nitrophorin 3.2 4.6 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
UPAR_LY6 1/1 115 124 .. 78 87 .] 7.4 6.4
Ribosomal_L21p 1/2 245 252 .. 90 97 .] 2.5 12
Ribosomal_L21p 2/2 328 336 .. 89 97 .] 2.1 17
ANF_receptor 1/1 60 483 .. 1 456 [] 347.4 1.6e-100
Nitrophorin 1/1 463 483 .. 162 181 .] 3.2 4.6
VSP 1/1 547 564 .. 1 18 [. 4.7 1.6
PSI_PSAK 1/1 567 581 .. 71 85 .. 8.2 1.1
7tm_3 1/1 579 850 .. 1 283 [] 401.9 6.1e-117
bZIP_Maf 1/1 1062 1242 .. 1 208 [] 375.3 6.4e-109
Alignments of top-scoring domains:
UPAR_LY6: domain 1 of 1, from 115 to 124: score 7.4, E = 6.4
*->sCCqkDLCNa<-*
sCCq+ +CN+
F45H11.4 115 SCCQTPGCNK 124
Ribosomal_L21p: domain 1 of 2, from 245 to 252: score 2.5, E = 12
*->HRQplTrv<-*
+RQ lTr+
F45H11.4 245 YRQVLTRL 252
Ribosomal_L21p: domain 2 of 2, from 328 to 336: score 2.1, E = 17
*->GHRQplTrv<-*
G+RQ +T++
F45H11.4 328 GFRQYYTAL 336
ANF_receptor: domain 1 of 1, from 60 to 483: score 347.4, E = 1.6e-100
*->avrgfpllvavgfafelinvgpallpgialgaaildvnslpnyalnl
+ g+++ + ++++ + n + +lg++i+d++++ a+++
F45H11.4 60 EQYGIQRSEIAMLTVKQLN----EELPFKLGLSIRDSCWTERIAMEQ 102
glkflrgidydsacdcsfavavavdlllekgvdewvvAiIGPscssaaia
+ +flr ++ +c++++++ + v+ A+IGP+ ss++ia
F45H11.4 103 TIAFLREGVAQC-SCCQTPGCNKKSVP----VV----AVIGPGKSSSTIA 143
varlanewniPlisygatapelsdketrfptflRTlPsdtkqgealvdll
v++l++ ++iP+++y+at p lsdk +f +flR++Psd +q++a+ +ll
F45H11.4 144 VQNLLQVFRIPQVGYSATTPDLSDK-EQFGYFLRVVPSDVFQAQAINRLL 192
khfgWtwvalvysdddygeegvaaliealeergg.icialkvsvpeidea
h++Wt+va++ys ++yge g+++l++ ++ r +++cia++++++ a
F45H11.4 193 HHYNWTYVAVLYSAGNYGEKGFESLEKLIAHRSSsVCIAYSEKIKTL--A 240
deedyrallkrikrrkstaRvivvcgsSVLiGgedlrqlleqavrlGmtg
+e++yr++l r+++++s+ +v+v++++ +++++ +++ + a + +
F45H11.4 241 SEQEYRQVLTRLDSQNSRPQVVVCFCE-GASMRMFFKAQKHLADGKMQMK 289
ggyvfisedwlsssldldpdlellapgaitlgtdgsdnvlgfayyavlvi
+++++s+ w++ ++ dle++a+g ++ ++ ++++gf++y + ++
F45H11.4 290 RFQWIGSDGWADRNDVVE-DLEEEAEGSFSIR-IHAPKIPGFRQYYTALH 337
tldspdnpefnefweelfecaltpfnfnks.esdrkCtgvecnsqalled
+ ++++np+f+efw++ f+c + + +k++e++r C+g+e++ +e
F45H11.4 338 PENNTMNPWFREFWQQKFNCQFAVSKEDKNnENIRICSGDENL----DEQ 383
tsvnpyagavyDaVylyAhAlhnellrnggg.ctlcaasdwrdGsqllry
+ ++p+ +v++++ +A++l+++ ++++ + tlc+++ r+G+ l++y
F45H11.4 384 YKEDPKLSQVINSIRVVALGLKAMYQDRCRDnSTLCTEMLSRNGTLLYEY 433
lrnvtFeGltGpeVqfDenRGDrnpdYdllnlqdsetgklevvgSGmPit
l+nvt+ + ++V+fD+n GD++++Yd+ln+ +++ +
F45H11.4 434 LLNVTYSDQFKQPVYFDRN-GDPPAWYDILNYIGTKDLD----------- 471
fyydgvgklvvv<-*
y++vg++ ++
F45H11.4 472 NPYNEVGSFKSI 483
Nitrophorin: domain 1 of 1, from 463 to 483: score 3.2, E = 4.6
*->dFvsTKdlkCeYDdv.qltSL<-*
++++TKdl Y +v++++S+
F45H11.4 463 NYIGTKDLDNPYNEVgSFKSI 483
VSP: domain 1 of 1, from 547 to 564: score 4.7, E = 1.6
*->CaeCklGyelsadktkce<-*
C C+lG+ + a +t ce
F45H11.4 547 CMNCTLGSWPNANRTGCE 564
PSI_PSAK: domain 1 of 1, from 567 to 581: score 8.2, E = 1.1
*->LvdvLAtgSlGHilG<-*
+++v ++S+GHil+
F45H11.4 567 IPEVVSWTSFGHILA 581
7tm_3: domain 1 of 1, from 579 to 850: score 401.9, E = 6.1e-117
*->lgivlvalAvlGLivltlfvlvvFvkhrdTPiVKasnreLSYlLLiG
i++++lAv G i+ ++++l+vF++h++TP+VK++ reLSY++L G
F45H11.4 579 --ILALVLAVTG-IITSMATLAVFLRHNSTPVVKSTTRELSYIILSG 622
lilcylcsflFIgkGtvekPstwsCilRrilfGlgFtlcySalLaKTirV
l+ cy+ sf++ + Pst+sC++ r++ ++F+++ySalL+KT+r+
F45H11.4 623 LVACYAVSFALLAT-----PSTTSCFITRVIPPIAFAVVYSALLTKTNRI 667
lriFrgakkpgstqkpkfispwaqvlivliltliQviicviWLvvePPrp
+ri++g+kk++ t+kp+f+ +++qv+i++il+++Q++i+++ L+ ++P+
F45H11.4 668 ARILAGSKKRILTKKPRFLTTFSQVVITWILVAVQCVIVGVGLMRDWPDA 717
didiysekekeedeDvsiapiileCnkgsvvaFlvvLgYdglLavlctll
+++ y+ +k +ileC+++ +Fl+++++d++L++lctl+
F45H11.4 718 TYAKYALPRK----------LILECDTET-KSFLIPFFWDFFLITLCTLY 756
AFltRnlPvdnFNEAKfItFSMYn................vltfCiVWvA
AF+tRnlP +nFNEAKfI+F+++++ ++ + ++++ ++++++VW+A
F45H11.4 757 AFKTRNLP-ENFNEAKFIGFTISQpakslpffqkehviifQYCTVVVWIA 805
FiPaYlstpgsaedykvqvaveifsilaSstvlLgclFaPKcYIILfkPe
F+ ++++t++ + v++fs+++S++v+L++lF+PK+YIIL++Pe
F45H11.4 806 FLVLHMGTTH-------KALVMSFSYSLSASVALALLFFPKLYIILMHPE 848
kN<-*
kN
F45H11.4 849 KN 850
bZIP_Maf: domain 1 of 1, from 1062 to 1242: score 375.3, E = 6.4e-109
*->askeskaqsaqlsptSppgaghvapaSagggggaGSgytimsgvGGG
++ke++++s++ls++Sp++++hvap+S++++++a+S+ytimsg
F45H11.4 1062 GFKEKCQLSKDLSRKSPKQFLHVAPKSRCSTSRAVSSYTIMSG---- 1104
sCvitRAALqPCRPLnqqlmsssgsvspsagsGapSplsledrfSDeqLV
nqqlms++gsvs+sagsG+pSp+s++d++SDe+L+
F45H11.4 1105 ---------------NQQLMSPMGSVSSSAGSGSPSPMSSFDHLSDEELA 1139
smSVRELNRtLkLRGlskeEvvRLKQKRRTLKNRGYAqsCRaKRvqQkhe
++SVR+LN+ kL+G+++++v+++KQKRRTLKNRGYA++CRa+Rv+++++
F45H11.4 1140 QISVRQLNQ--KLMGQDRNVVMQWKQKRRTLKNRGYALNCRARRVNNQVQ 1187
LEkeKaqLaqQleqLkeEvsrlarErDaykakyerLlsfivpvARsPvsg
LE+++++L++Q+++L+e++s++++++++y++++++++++ivp s+
F45H11.4 1188 LEADNMMLRNQIKTLREALSEAQMRLHYYEPVFYQAYPSIVP------ST 1231
ageagsssdsp<-*
++++++s++++
F45H11.4 1232 TSPVTVSLPTI 1242