Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm3/seq/F44F4.4
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Query:  F44F4.4  CE01000  locus:ptr-8  status:Partially_confirmed TR:Q20404 protein_id:CAA85455.1

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
Patched         Patched family                         1448.7          0   1
HSP90           Hsp90 protein                             6.3       0.61   1
Ribosomal_L37ae Ribosomal L37ae protein family            5.9        3.7   1
RolB_RolC       RolB/RolC glucosidase family              4.3        5.2   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
HSP90             1/1     100   116 ..     1    20 [.     6.3     0.61
Ribosomal_L37ae   1/1     544   555 ..    80    91 .]     5.9      3.7
RolB_RolC         1/1     631   671 ..     1    41 [.     4.3      5.2
Patched           1/1      42   889 ..     1   957 []  1448.7        0

Alignments of top-scoring domains:
HSP90: domain 1 of 1, from 100 to 116: score 6.3, E = 0.61
                   *->EYLEErRlKelvKKySeFIg<-*
                        LEE+RlKe+v K S+FI+
     F44F4.4   100    --LEEQRLKEVV-KVSDFIS    116

Ribosomal_L37ae: domain 1 of 1, from 544 to 555: score 5.9, E = 3.7
                   *->sairRLrelkEs<-*
                      s+++RL+elkE+
     F44F4.4   544    SNVERLVELKEK    555

RolB_RolC: domain 1 of 1, from 631 to 671: score 4.3, E = 5.2
                   *->meytrprfqprdltlitdsdeLkreLeaAfedYrsflqktL<-*
                      + ++  +f+  dl + +++++L ++ + A+e++++++++t+
     F44F4.4   631    KFMFTTGFHGQDLKDWNKRGQLLKRWRGAVEEFKDDFNTTV    671

Patched: domain 1 of 1, from 42 to 889: score 1448.7, E = 0
                   *->vlsskilytftpsDirksytergvrsedeplverkFfpgdgkpiarf
                      v+s+k+++t++ s+i+ +y++++++s++e++++++F+++dg+ i+++
     F44F4.4    42    VMSIKLALTPKVSAID-GYASDDSMSRHEFKTFQQFLDSDGPGITTA 87

                   viitakarnsedytrpNiLdikyLnevvqvndfiltnvtipvsgalkkit
                   + i+++++n+      ++L++++L+evv+v+dfi+tn++++vsg    ++
     F44F4.4    88 ILIRSSITNG------SLLEEQRLKEVVKVSDFISTNFKLNVSG----VE 127

                   lsfkdlCssfcdincpvnqhyngLdtlailrsnlhn...sridltYPtmt
                   ++f+++C++fc++n+pv+q+yng   l+il++n++++ ++ridl+YPt++
     F44F4.4   128 KNFNQFCRGFCQANEPVRQYYNG---LQILGKNQTDgisKRIDLSYPTSN 174

                   ffgtkiylgpnfgGVkldpgeNdvekllDsltklklvdtkseegniksvk
                   ffg+k++l+pnf+G++++p                      e+++++s++
     F44F4.4   175 FFGRKFSLIPNFFGISMSP----------------------EGQHLNSSN 202

                   aivLyyrlkrdpeeveedskeWElsledyleneyksdshievtifsdqvl
                   +ivLy+r++r+p+++++++k+WEl+++d++++ey+sd +i+v+++s++v+
     F44F4.4   203 LIVLYFRAERYPDWSTKTVKQWELRVRDHFAKEYSSD-LIIVDVMSQTVV 251

                   edElvrngltlvPffvvgFaiLvtFsvltsvvlavrrsgslhidwvssKp
                   e+E+vr+gl+l+Pf++vgF+i+ +F+++t++++av   ++++++++++K+
     F44F4.4   252 ESEIVRAGLSLQPFLIVGFVIMSIFCTVTTMFSAV---YLYSQKATFNKV 298

                   iLAilgvltPlmAivsAfGlLfwlGfrFnsIlcVmPFLVLGAIGVDDmFL
                   +L+i+++++P+mA+++A+G+Lf++G++F++I+c++PFLVL AI+VDD+FL
     F44F4.4   299 ALSIIACINPFMACGTAMGILFFCGVTFSPIMCITPFLVL-AISVDDSFL 347

                   MvhaWqrttrslssrarK.vvkkRmgevlvEaGPSItITSlTnvLSFgIG
                   M+haW+r++++++++++K++++++mgevlvE+GP+I+I+++Tn+L+F+IG
     F44F4.4   348 MLHAWNRLESWRTAPLDKpMREHMMGEVLVETGPAISISAFTNMLAFTIG 397

                   aiTptPeIqlFCiytavAiffdfiYQlTFFaAilaiagkyEmkgrhslfl
                   aiT++PeI++FC+++a+Aif+d++YQ TF++A++++ g+++ ++
     F44F4.4   398 AITSPPEIRIFCFGNAAAIFMDMFYQATFYTACMTLLGDTK-NS------ 440

                   riTakavdaaetespkklkkqrlksrgsakaaPvekegeknSkfsevees
                                        +  s+++++
     F44F4.4   441 ---------------------EGVSEKTKR-------------------- 449

                   leseksssdssksheaeqktavvkfflniYcpfllnpkvrvcvllvyvvY
                               ++e++   +vv +fl++Y+++++n++v++ ++lv++v+
     F44F4.4   450 ------------IQERMG--NVVGRFLKWYVNAISNIFVSFGIVLVWAVF 485

                   laiaiYGctnlkegLdPskLllkDSpLveilrlrekhvwpyGsqvtVvVN
                   +++a+ G+t+l+++L+Psk++lkDSp+++++rlr+++v+py+++v+V+VN
     F44F4.4   486 IGFAVLGLTRLHVELRPSKFFLKDSPMLYMDRLRTNEVVPYYTPVHVIVN 535

                   NPPDLtnpenrdrllemvdeFEntpyalGkWEnsTkfWLrdYekFlsssE
                   NP+DLtn++n++rl e+++++E++p+a+G+  +sTkf+L+d+++++ss
     F44F4.4   536 NPGDLTNDSNVERLVELKEKLEHMPNAIGA--PSTKFFLDDFVQYRSS-- 581

                   einleaseledeeeeidevdpvsvvvkdkqewifydllewFlkspgfshW
                       +a+e+e++++e+d            +e+ +++++e+Fl++p+fs+W
     F44F4.4   582 ----FAEEIEMDIAEDD------------SES-EKSDIEQFLEWPEFSFW 614

                   qgdlvwdnktdketteikkFrFttgyHgkdlstwtdRtkllkewRgvAde
                   +g+l++dn+t  ++++++kF+Fttg+Hg+dl++w++R++llk+wRg ++e
     F44F4.4   615 RGFLRFDNQT--HPHNVTKFMFTTGFHGQDLKDWNKRGQLLKRWRGAVEE 662

                   ypddFNVTVFdedafFlDqilsilpttiQsiiwtlicMavVCflFIpnpi
                   ++ddFN+TVF+edafFlD+i+si+++t+Q++++t+i++++VCflFI+++
     F44F4.4   663 FKDDFNTTVFTEDAFFLDMIDSIPTVTWQTTLATFIFVSLVCFLFISDIL 712

                   tvfvitvsiaSIdiGVfGfLSLWGVdLDPisMitiIMSIGFSVDfsAHia
                   tv++++v+++++++GVfG+LSL GV+LDP++M++ IM+IGFSVD++AH+a
     F44F4.4   713 TVMIVSVATLVTSVGVFGYLSLLGVTLDPVIMSIAIMCIGFSVDIPAHVA 762

                   YhFyrskgsesrs..........................ikkiplktpde
                   +hFy++k+++++s+++++++++ ++++  +++++++++++++++++++++
     F44F4.4   763 FHFYAAKAKKHASshsqpsphqvtspdivhststtsssdSSISTPNSFET 812

                   RvadALealGWPviQAalSTiLcvlvLlFVpsYmvvvFfKTifLVVvlGl
                   ++++AL+++G+PviQA++ST++c l+L F+++Ym+++F+ + +L+V+l+l
     F44F4.4   813 NLNFALSSVGFPVIQAGVSTDFCALPLGFMELYMAKMFALSLTLCVSLSL 862

                   LHGLifLPilLslfvtssrifggdviirtsnakikkpseq<-*
                   +HGLi++P+lLs++++             ++++ k+++ +
     F44F4.4   863 IHGLIVIPALLSVQHH-------------IVHAVKRCFGR    889



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