Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F42A9.1a
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Query: F42A9.1a CE10292 kinase status:Partially_confirmed TR:Q20320 protein_id:AAB03166.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
DAGKc Diacylglycerol kinase catalytic domain (p 217.1 2.5e-61 1
DAGKa Diacylglycerol kinase accessory domain (p 199.1 6.9e-56 1
SAM SAM domain (Sterile alpha motif) 86.8 3.6e-23 1
DAG_PE-bind Phorbol esters/diacylglycerol binding dom 54.7 7e-13 3
SapB_1 Saposin-like type B, region 1 6.7 1.7 1
MscL Large-conductance mechanosensitive channe 5.1 3.8 1
C4 C-terminal tandem repeated domain in type 4.6 3.8 1
DUF344 Domain of unknown function (DUF344) 3.5 8.3 1
MutS_III MutS domain III 3.3 9.7 1
Herpes_gE Alphaherpesvirus glycoprotein E 2.9 1.2 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
DAG_PE-bind 1/3 52 101 .. 1 51 [] 45.0 2.8e-10
C4 1/1 136 144 .. 108 116 .] 4.6 3.8
DAG_PE-bind 2/3 125 150 .. 1 27 [. 11.3 0.29
DAG_PE-bind 3/3 183 204 .. 30 51 .] 13.2 0.093
DAGKc 1/1 244 369 .. 1 154 [] 217.1 2.5e-61
SapB_1 1/1 387 417 .. 8 39 .] 6.7 1.7
MscL 1/1 388 423 .. 103 145 .] 5.1 3.8
MutS_III 1/1 460 808 .. 157 202 .. 3.3 9.7
DAGKa 1/1 839 998 .. 1 190 [] 199.1 6.9e-56
DUF344 1/1 1075 1095 .. 209 229 .] 3.5 8.3
Herpes_gE 1/1 1189 1204 .. 499 514 .] 2.9 1.2
SAM 1/1 1221 1284 .. 1 68 [] 86.8 3.6e-23
Alignments of top-scoring domains:
DAG_PE-bind: domain 1 of 3, from 52 to 101: score 45.0, E = 2.8e-10
*->HrFkrttfyksptfCdhCgellwglakQGlkCsnCglnvHkrChekV
H++ t+ ++ptfC++C+e l g + G+ C+ C++++H +C ++
F42A9.1a 52 HHWTETNH-PRPTFCNYCREKLNGVPWHGYTCDICKVKAHRKCRDNL 97
ptnC<-*
+ C
F42A9.1a 98 TEQC 101
C4: domain 1 of 1, from 136 to 144: score 4.6, E = 3.8
*->SRCqVCekp<-*
S C+VCekp
F42A9.1a 136 SKCSVCEKP 144
DAG_PE-bind: domain 2 of 3, from 125 to 150: score 11.3, E = 0.29
*->HrFkrttfyksptfCdhCgellwglak<-*
H+++ ++ + p C++C++ ++ +k
F42A9.1a 125 HQWMEGNL-PMPSKCSVCEKPCGSVRK 150
DAG_PE-bind: domain 3 of 3, from 183 to 204: score 13.2, E = 0.093
*->lkCsnCglnvHkrChekVptnC<-*
++C++Cg+ vH+ C +++ C
F42A9.1a 183 YRCIWCGCCVHDTCIGNLARAC 204
DAGKc: domain 1 of 1, from 244 to 369: score 217.1, E = 2.5e-61
*->plLVfvNPkSGggqgekelaseskllqkfrelLnprqVfdltktggp
pl+V++N kSG+ qg+ ++++kfr++Lnp+qVfd++ +gp
F42A9.1a 244 PLIVLINAKSGDSQGQ-------RIIKKFRRILNPIQVFDIIA-TGP 282
avglelfrdlpdfkeqdqGddrvlvcGGDGTvgwVlnaldklelplqcqr
+++l++f++l++f rvlvcGGDGTvgwVl+a d+l+l+++cq
F42A9.1a 283 DFALTFFSHLESF--------RVLVCGGDGTVGWVLSAFDRLNLHSKCQ- 323
efpkPpvgilPlGTGNdLarvLgwgggydgaqlinekllkilgdaleead
++ilPlGTGNdLarvLgwg+++ + ++ll+++ + +e+a+
F42A9.1a 324 ------LAILPLGTGNDLARVLGWGHAFYD-----DTLLPQVVRTMERAH 362
tvmldrW<-*
t+mldrW
F42A9.1a 363 TKMLDRW 369
SapB_1: domain 1 of 1, from 387 to 417: score 6.7, E = 1.7
*->emvVkevenlLkdnkTqeeIlkaLeklCdlLP<-*
e v+++v ++L++ +T + I++a ++lC ++
F42A9.1a 387 ELVIEKVRTFLEAEQTWD-IIHAANQLCTTIR 417
MscL: domain 1 of 1, from 388 to 423: score 5.1, E = 3.8
*->KaiNkLrrkkeveEEaeaEAqpdPvLEaqevLLtEIRDLLkqq<-*
++i+k+r + e+e ++ d ++ a+ L+t+IRDL
F42A9.1a 388 LVIEKVRTFLEAE---QT---WD-IIHAANQLCTTIRDLVHSV 423
MutS_III: domain 1 of 1, from 460 to 808: score 3.3, E = 9.7
RF xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
*->ldlLekaInedPwasalPlllrdGgvIksGyd...............
ld L k+++ed+ +l++ g+ +G d+++++++ +++++
F42A9.1a 460 LDRLMKSLKEDA------NCLEESGF-EPGDDddcstgdemlkkrds 499
RF
..................................................
++ ++ ++ + + ++ +++ +++++ ++++ + ++++++++++
F42A9.1a 500 vvnranslkkafrevismaekgidqhyrdpntactkrerfrkkrskttps 549
RF
..................................................
+ ++++ ++++ +++++++ + ++++++++ ++ +++ + +++++
F42A9.1a 550 vltishsnlssssacsppcspagedppqddqkefrsasckatfeishsqs 599
RF
..................................................
+++ + + ++ ++ + +++ ++ ++++++ ++ +++ +++ +
F42A9.1a 600 sssavltalfnaqsartydelekpsigtvhpptpgatrepstaydddeen 649
RF
..................................................
+ +++ ++++++++++ +++ + +++++++++ ++++ +++ + +
F42A9.1a 650 envenrkeidqksnskkssvstpeditkgspdrpriysdttlnknmekmk 699
RF
..................................................
+++ ++ +++ ++ ++++++++ + + +++++++ + ++++ ++ +
F42A9.1a 700 sqslhpicssadkmkqshsdsslyadyehlegsssgcgagasgstlspar 749
RF xxxxx
.............................................lepLq
+++ ++++ + ++++ +++ + +++++ +++++ ++ +++ +e L+
F42A9.1a 750 asdsatwsrikerkrtvgsdlglsssshlrscrnmlsgfaggsliAEILL 799
RF xxxxxxxxx
alAeaLAeL<-*
+A++L+++
F42A9.1a 800 LNARVLSQM 808
DAGKa: domain 1 of 1, from 839 to 998: score 199.1, E = 6.9e-56
*->iINNYFSiGVDAsialrFHimREknPekFnSRmkNKlwYfefGtset
++NNYF+iG DA ial+FH RE+ ek SR k +wY+ +G++e+
F42A9.1a 839 VMNNYFGIGLDAKIALEFHNKREES-EKTRSRSKLFMWYGILGGKEL 884
lastcknLhesvelecdGqevdLsnrDaslEGIiiLNIPSygGGsnLWGe
+t++nL++ ++lecdG+ +dL+ sl+GI+iLNIPSy GG+n WG+
F42A9.1a 885 MHRTYRNLEQRIKLECDGVPIDLP----SLQGIVILNIPSYSGGANFWGR 930
skkgkgdigefkksitdpkdlktavqdidDgLlEVVGlegamhmgQiyTs
+++ + vq++dD+ lEVV l g++h + +
F42A9.1a 931 ----------------NKDGPEFTVQSFDDRILEVVALFGVIHVATSRVP 964
iqlklasWvkLmkgrRlaQCsevRlkDtiktkktlPMQVDGEP<-*
++l + +R+aQC+ vR+ +i+ +P+QVDGEP
F42A9.1a 965 NAVRLQN-------HRIAQCRHVRI--VILGDEPIPVQVDGEP 998
DUF344: domain 1 of 1, from 1075 to 1095: score 3.5, E = 8.3
*->ARLnvirhlLsaleyeekkrp<-*
ARL v++ lL++l++++ + +
F42A9.1a 1075 ARLGVSSVLLQSLDDANAIVK 1095
[output cut off at A = 10 top alignments]