Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F42A10.2a
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Query: F42A10.2a CE01293 status:Partially_confirmed TR:Q20307 protein_id:AAA19073.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
ERM Ezrin/radixin/moesin family 533.2 1.8e-156 2
Band_41 FERM domain (Band 4.1 family) 234.3 1.3e-74 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Band_41 1/1 16 216 .. 1 210 [] 234.3 1.3e-74
ERM 1/2 218 517 .. 1 351 [. 535.2 4.6e-157
ERM 2/2 574 654 .] 316 392 .] 3.5 8.4
Alignments of top-scoring domains:
Band_41: domain 1 of 1, from 16 to 216: score 234.3, E = 1.3e-74
*->ctvtllDstveeFkveKkdkGqvLLdkVfkhLglrEkdYFGLQylDd
+v+++D+ +e ++eK ++G L++ V++ +glrE++YFGLQ++
F42A10.2a 16 AKVSTMDADLEKIVIEKTWTGRHLFEAVCRIIGLRETWYFGLQFTN- 61
DnsskdsptWLdpsKkirkQdvkkee...PytLhFRvKFYpeDvpneLrq
k p WL +K+i Qd+ k +++ +++F+vKFYpeDv+ e +
F42A10.2a 62 ---KKNIPCWLQNDKTICGQDIQKDTsdgTFNFLFLVKFYPEDVEPEIIL 108
eiTrylffLQvkqdIleGrlpCpfetAvLLASYaVQsefGDYneslHkaG
+ Tr+lffLQ+++ Il+ l+C++e++vLLAS+aVQ+ GD e++ +
F42A10.2a 109 DATRHLFFLQIREAILSMNLYCSPEASVLLASFAVQAMHGDCTEEVGPID 158
RtCLCYLsdekllPqRVlnqkqltkddfEekIaelHkeHrGmspdeAele
++k lP+ V++q+ + d++ ++I + G+s++eAele
F42A10.2a 159 --------LDKHLPKSVIDQYDMSADMWRDRIKRWWSRNAGQSREEAELE 200
YLkiArdLemYGVdff<-*
YL A+dLemYG+ ++
F42A10.2a 201 YLRVAQDLEMYGILYY 216
ERM: domain 1 of 2, from 218 to 517: score 535.2, E = 4.6e-157
*->IkNKKGTdLwLGVDALGLNIYekdDrLTPKIgFPWSEIRNISFnDKK
I+N+K+TdL+LG++A+GL+IY++++r+TP+++F+WSEI+NI+F+++K
F42A10.2a 218 ICNNKETDLHLGISAQGLGIYKGVNRITPRPFFSWSEIKNIQFKNRK 264
FvIKPiDKKapdFvFyaprlrINKrILaLCmGNHeLYMRRRKPDTIEVQQ
F++K++DK++ ++F++++++I+++IL+LC+G+H+LY+RRR+PDT+EVQQ
F42A10.2a 265 FHMKTVDKST--ISFRSRETSIDSSILDLCIGTHNLYLRRRQPDTLEVQQ 312
MKaQAkEEKqrKqaERekLarEkkaREiaekekEeaEreqqEleerleqm
M++QAkE+Kqr++aE++k+a+E+k+R +++E+e++E+++++e+m
F42A10.2a 313 MRSQAKEDKQRRAAEQAKVALERKER-------QQMEKEYKEMKQKVEVM 355
eEelrkaqeeLeeaeekadeLeeklkqeeeeaqkLekkqseleeenrrLe
++el+kaqe++++aee++d+L+ek++++e+e+ +L+k++se+e+e++rL+
F42A10.2a 356 TLELMKAQENIRKAEEANDQLAEKARHSEHETLMLYKQKSEVEAECNRLS 405
eeamkseeererLeaevdeaeaevaqleeelekkeeEaeqlqtelrsaqe
+++mksee+++r+e++++eae++++q++++l++++ +a++++t+++s+++
F42A10.2a 406 MNNMKSEEALLRMERKAREAEILAKQMSMSLADVSLDANRKMTQYSSQSA 455
keeeaneellevlaaptappmhhvsapsaELttdngsglesgdngeeasa
+++++n++ +++sg++sg++g+++++
F42A10.2a 456 LIIDPNWH-------------------------QQVSGHQSGHPGMPSTG 480
dlePkEFiLtdedmkdlsnEiEeervteaeknerlqtqLkaLksELssvr
+++ +l ++++t+++++++++++L++++s++ss++
F42A10.2a 481 SFH------------QL-----QSLDTHTHPQQMMSRSLNMPSSAFSSPI 513
denk<-*
++n+
F42A10.2a 514 PSNQ 517
ERM: domain 2 of 2, from 574 to 654: score 3.5, E = 8.4
*->nEiEeervteaeknerlqtqLkaLksELssvrdenketa.....nDi
+E+E++r +++ + +++L +L+ +++ ++ +++++++++ D
F42A10.2a 574 MELEKSRSEYETRARIFKEHLEELRGDIDGLKRDGNVQNgqhreHDA 620
lHeENsvRaGrDKYkTLRqIRkGNTKqRVDqFEsM<-*
H+ N v G DK T R G +qR F M
F42A10.2a 621 VHAQN-VAHGFDKFTTMRMSMRGTPRQRAQAFDGM 654