Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm3/seq/F40E10.4
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Query: F40E10.4 CE23711 locus:slt-1 EGF-like protein slit like status:Partially_confirmed TR:Q20204 protein_id:CAA93668.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
LRR Leucine Rich Repeat 186.9 3.2e-52 19
LRRCT Leucine rich repeat C-terminal domain 143.4 8.7e-47 4
EGF EGF-like domain 125.8 7.7e-34 8
LRRNT Leucine rich repeat N-terminal domain 111.3 1.9e-29 4
laminin_G Laminin G domain 77.1 1.2e-20 1
Ribosomal_S4e Ribosomal family S4e 6.5 1.9 1
Amb_V_allergen Amb V Allergen 3.8 8.5 1
Viral_Rep Putative viral replication protein 1.5 9.8 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
LRRNT 1/4 16 43 .. 1 31 [] 31.8 4.6e-07
Ribosomal_S4e 1/1 44 57 .. 72 85 .] 6.5 1.9
LRR 1/19 45 68 .. 1 25 [] 11.4 0.23
LRR 2/19 69 92 .. 1 25 [] 11.0 0.3
LRR 3/19 93 116 .. 1 25 [] 16.6 0.0078
LRR 4/19 117 140 .. 1 25 [] 11.3 0.24
LRR 5/19 141 164 .. 1 25 [] 7.5 3
LRR 6/19 165 186 .. 1 25 [] 12.3 0.13
LRRCT 1/4 195 243 .. 1 54 [] 51.4 5.7e-16
LRRNT 2/4 259 286 .. 1 31 [] 39.4 3.5e-09
LRR 7/19 288 311 .. 1 25 [] 17.6 0.0039
LRR 8/19 312 335 .. 1 25 [] 21.8 0.00026
LRR 9/19 336 359 .. 1 25 [] 20.1 0.00078
LRR 10/19 360 383 .. 1 25 [] 10.3 0.49
LRR 11/19 384 407 .. 1 25 [] 17.0 0.0059
LRRCT 2/4 417 466 .. 1 54 [] 49.5 2.6e-15
LRRNT 3/4 484 511 .. 1 31 [] 32.1 3.9e-07
LRR 12/19 513 537 .. 1 25 [] 1.0 2e+02
LRR 13/19 538 561 .. 1 25 [] 23.5 8.7e-05
LRR 14/19 562 585 .. 1 25 [] 8.7 1.3
LRR 15/19 586 609 .. 1 25 [] 15.2 0.019
LRRCT 3/4 619 640 .. 1 23 [. 15.8 0.0005
LRRNT 4/4 676 703 .. 1 31 [] 30.9 8e-07
LRR 16/19 705 728 .. 1 25 [] 3.6 39
LRR 17/19 729 752 .. 1 25 [] 21.8 0.00025
LRR 18/19 753 776 .. 1 25 [] 12.7 0.096
LRR 19/19 777 800 .. 1 25 [] 19.8 0.00093
LRRCT 4/4 810 859 .. 1 54 [] 45.1 7.6e-14
EGF 1/8 873 905 .. 1 45 [] 32.0 2.4e-07
EGF 2/8 912 944 .. 1 45 [] 24.4 3.5e-05
EGF 3/8 951 969 .. 1 29 [. 5.9 5.6
EGF 4/8 982 997 .. 25 45 .] 15.7 0.0097
Amb_V_allergen 1/1 987 1004 .. 1 18 [. 3.8 8.5
EGF 5/8 1004 1037 .. 1 45 [] 32.7 1.6e-07
EGF 6/8 1044 1075 .. 1 45 [] 27.3 5.1e-06
EGF 7/8 1091 1123 .. 1 45 [] 26.3 1e-05
laminin_G 1/1 1153 1286 .. 1 155 [] 77.1 1.2e-20
EGF 8/8 1307 1340 .. 1 45 [] 15.7 0.0099
Viral_Rep 1/1 1365 1372 .. 293 300 .] 1.5 9.8
Alignments of top-scoring domains:
LRRNT: domain 1 of 4, from 16 to 43: score 31.8, E = 4.6e-07
*->aCpreCtCspfglvVdCsgrgLtlevPrdlP<-*
Cp+eC+C +++V C g++Lt evP +P
F40E10.4 16 TCPAECVCV--DRTVSCVGQQLT-EVPQNIP 43
Ribosomal_S4e: domain 1 of 1, from 44 to 57: score 6.5, E = 1.9
*->gDsikislpeqeIv<-*
+D+i ++l+++eI+
F40E10.4 44 NDTIRLDLQDNEIT 57
LRR: domain 1 of 19, from 45 to 68: score 11.4, E = 0.23
*->nLreLdLsgNnltgslppdafsgLt<-*
+LdL++N++t ++ p+ fs+L
F40E10.4 45 DTIRLDLQDNEIT-KIGPNDFSSLM 68
LRR: domain 2 of 19, from 69 to 92: score 11.0, E = 0.3
*->nLreLdLsgNnltgslppdafsgLt<-*
nL+ L L +N++ ++ + +fs+L
F40E10.4 69 NLKALQLMDNQIV-TIHNQSFSSLV 92
LRR: domain 3 of 19, from 93 to 116: score 16.6, E = 0.0078
*->nLreLdLsgNnltgslppdafsgLt<-*
L+ L+Ls+N+++ +lp+++f++
F40E10.4 93 FLQKLRLSRNRIR-HLPDNVFQNNL 116
LRR: domain 4 of 19, from 117 to 140: score 11.3, E = 0.24
*->nLreLdLsgNnltgslppdafsgLt<-*
+L++LdLs N +t +++ ++g
F40E10.4 117 KLTHLDLSENDIT-VVSDAQLQGPE 140
LRR: domain 5 of 19, from 141 to 164: score 7.5, E = 3
*->nLreLdLsgNnltgslppdafsgLt<-*
L++L+L+ N++ l+++++s++
F40E10.4 141 FLEVLNLDKNHIF-CLENNVISSWV 164
LRR: domain 6 of 19, from 165 to 186: score 12.3, E = 0.13
*->nLreLdLsgNnltgslppdafsgLt<-*
+L++L L+gN+lt ++++ s+ +
F40E10.4 165 SLEVLTLNGNRLT-TFEE--PSNAR 186
LRRCT: domain 1 of 4, from 195 to 243: score 51.4, E = 5.7e-16
*->NPfnCDCelrwLlrWlretnprrledqedlrCasPeslrGqpllell
NP+nCDC+lrw++ Wl++ + ++ + Ca P +l+G + +e+l
F40E10.4 195 NPWNCDCRLRWMRKWLEK----AEGQN-KTVCATPLNLQG-SSIEIL 235
p.sdfsCp<-*
++ +C+
F40E10.4 236 QdKFMTCS 243
LRRNT: domain 2 of 4, from 259 to 286: score 39.4, E = 3.5e-09
*->aCpreCtCspfglvVdCsgrgLtlevPrdlP<-*
+Cp +CtC+ g++VdC++ gLt vP lP
F40E10.4 259 ICPLPCTCT--GTTVDCRDSGLT-YVPTNLP 286
[output cut off at A = 10 top alignments]