Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F37D6.1
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Query: F37D6.1 CE05818 BRCA1 C Terminus (BRCT) domain (4 domains) status:Partially_confirmed TR:Q20129 protein_id:CAA99847.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
BRCT BRCA1 C Terminus (BRCT) domain 254.4 2e-76 6
H-kinase_dim Signal transducing histidine kinase, hom 6.8 2.8 1
DEC-1_REPEAT Dec-1 repeat 5.4 6.2 1
aakinase Amino acid kinase family 4.2 4.2 1
PetN PetN 3.8 4.7 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
BRCT 1/6 175 262 .. 1 99 [] 51.9 1.5e-14
BRCT 2/6 272 311 .. 1 49 [. 16.0 0.0014
PetN 1/1 549 561 .. 1 13 [. 3.8 4.7
BRCT 3/6 485 574 .. 1 99 [] 64.0 2.9e-18
DEC-1_REPEAT 1/1 562 590 .. 1 30 [] 5.4 6.2
BRCT 4/6 621 704 .. 1 99 [] 27.6 3.9e-07
BRCT 5/6 713 794 .. 1 99 [] 34.7 2.7e-09
H-kinase_dim 1/1 989 1001 .. 52 64 .] 6.8 2.8
BRCT 6/6 971 1060 .. 1 99 [] 60.1 4.6e-17
aakinase 1/1 1172 1189 .. 294 313 .] 4.2 4.2
Alignments of top-scoring domains:
BRCT: domain 1 of 6, from 175 to 262: score 51.9, E = 1.5e-14
*->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
+++f+++++++tg l+ ++++el+e+i + G+v +
F37D6.1 175 SSVFQDVKISFTG-----------LNLTKKqELYEKIGWMCGVVGdA 210
lskktthvivgenagsklekalkaialgipivteeWlldcikegkllped
l + tth+++++ + ++++ka+ ++ i+++++ W+ d++++ + +
F37D6.1 211 LYHETTHLVTEKAEQTEKYKAA--VNNSIKLMRIGWIDDLWETSQTTMGR 258
pyll<-*
+l
F37D6.1 259 FSAL 262
BRCT: domain 2 of 6, from 272 to 311: score 16.0, E = 0.0014
*->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
+f+gl +t+ d+ +r+ ++lie +GGkv +
F37D6.1 272 LRVFEGLEMAITS-----------IDGADRtNFIQLIEDHGGKVPgT 307
lskk<-*
sk+
F37D6.1 308 MSKT 311
PetN: domain 1 of 1, from 549 to 561: score 3.8, E = 4.7
*->mdivslgWaalmv<-*
++iv++gW+ +v
F37D6.1 549 IAIVTVGWVVECV 561
BRCT: domain 3 of 6, from 485 to 574: score 64.0, E = 2.9e-18
*->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
+lf+++ f+++g d ++ +++++++++ G++ +
F37D6.1 485 GDLFENCMFYICG-----------VDESRMeKWRRFLNETGATRVaK 520
lskktthvivgenagsklekalk.aialgipivteeWlldcikegkllpe
+++ t++v+v++n+ ++ + +k+ + i ivt W+++c+k++k++ +
F37D6.1 521 FTSATNVVVVSPNQ-QERITIRKhLHQEDIAIVTVGWVVECVKQRKMISV 569
dpyll<-*
+ y++
F37D6.1 570 EGYQW 574
DEC-1_REPEAT: domain 1 of 1, from 562 to 590: score 5.4, E = 6.2
*->qnpmmmqqmqqRqWsEdqakiqqaqqpmmq<-*
++ m+ ++ qW+E+ a q q ++q
F37D6.1 562 KQRKMI-SVEGYQWTENTADESQSSQSQLQ 590
BRCT: domain 4 of 6, from 621 to 704: score 27.6, E = 3.9e-07
*->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
+fs +t +++++ d+e ++lke+i ++GGk +++
F37D6.1 621 VGIFSYHTYCVHCS----------VDQEVSdDLKEKIPLNGGKLMdD 657
lskktthvivgenagsklekalkaialgipivteeWlldcikegkllped
+++ ++ + + ++l +vt +++++i ++++l+ +
F37D6.1 658 PDYAEFVIFGHSGPMHELISF-------DAVVTDFYIYASIGNNRFLNRS 700
pyll<-*
y l
F37D6.1 701 CYPL 704
BRCT: domain 5 of 6, from 713 to 794: score 34.7, E = 2.7e-09
*->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
+f++ f l + d+ r+ ++++ie +GG+++++
F37D6.1 713 ILIFNQRGFQLKC-----------KDPFLRdRVRDIIEDNGGRIVeQ 748
lskktthvivgenagsklekalkaialgipivteeWlldcikegkllped
l +k ++ ++ ++++ +++ ++++++W+++++ +++l+p+d
F37D6.1 749 LEPKDFIIMIDAEDNPP--------RYHSRTLDFSWIIASVSRCRLQPID 790
pyll<-*
++l+
F37D6.1 791 NFLY 794
H-kinase_dim: domain 1 of 1, from 989 to 1001: score 6.8, E = 2.8
*->rltreLQdsVMki<-*
+++ +LQ+++Mk+
F37D6.1 989 QRAADLQETIMKL 1001
BRCT: domain 6 of 6, from 971 to 1060: score 60.1, E = 4.6e-17
*->eklfsgltfvltgtknaaviieamldseer.elkelieklGGkvt.s
+ + +f l+ ++ +d+++ +l+e i klGG+++++
F37D6.1 971 RRYAMNPRFLLSVSN---------MDPQRAaDLQETIMKLGGTIErE 1008
lskktthvivgenagsklekalkaialgipivteeWlldcikegkllped
++k++th+i+++ ++ + +++ ia g++++t+++++++ + g++l+e+
F37D6.1 1009 FNKDVTHLIASNMQRAPKVLCS--IAAGKWCLTPDYVTKSAEVGRWLDEK 1056
pyll<-*
+++
F37D6.1 1057 SFEW 1060
aakinase: domain 1 of 1, from 1172 to 1189: score 4.2, E = 4.2
*->vrAailavrsgvgipviItn<-*
+++a+l +r +ip+++++
F37D6.1 1172 PQSAVLLKRD--NIPIYVFD 1189
[output cut off at A = 10 top alignments]