Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F33C8.3
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
Query: F33C8.3 CE05798 locus:tsp-8 tetraspanin status:Partially_confirmed TR:Q19983 protein_id:CAA93655.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
transmembrane4 Tetraspanin family 254.1 1.9e-72 1
TB TB domain 8.6 0.35 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
transmembrane4 1/1 7 263 .. 1 285 [] 254.1 1.9e-72
TB 1/1 258 276 .. 1 19 [. 8.6 0.35
Alignments of top-scoring domains:
transmembrane4: domain 1 of 1, from 7 to 263: score 254.1, E = 1.9e-72
*->clKyllfllNflfwLlGilllgvGiWllvdkgsfssllel..ssscf
l+ + fl+Nf fwL+G++++g+GiWll+d++ + ++ +++ ++ f
F33C8.3 7 ALRIVTFLFNFAFWLSGVVVFGLGIWLLFDPAASDFFALHstHPGAF 53
laapyvlIavGaviflvgflGccGAikEsrclLllYfvfLlllfiaelaa
+++++ l+++Ga+i+lvg +Gc+GA+k ++c+L+++ ++L+l f++elaa
F33C8.3 54 RYVGWFLVGAGAIIILVGYFGCIGAWKMNQCALAFFCCILILAFFLELAA 103
gilafvfrdvklesel.getlkeaikkyystddysnwlqkVndkWeIRsC
++ +f+ ++ +++++++ +++++ ++y+s+ +
F33C8.3 104 AVTLFHKQE-HIKHYVeSSMYDTIRNRYSSETAF---------------- 136
LvksvCnlteawDalQsqfkCCGPPvnggfyytDTfWfpqwssnyfsgns
++a+D++Q++f+CCG v + ytD W
F33C8.3 137 --------KDAFDTVQEKFECCG--VKT---YTD--W------------- 158
ev.dri.s.vdcklwrn.v.vlCydcsv.p.cass.ktelesprpcivsn
++ +++ +++ ++ ++++ ++ + ++ ++ ++++ ++++++ +c+ ++
F33C8.3 159 LSaRWDaEpSTQLEVNEeDaGRIEHGIGaFgGNKGtGYGRVPSSCCNEHG 208
cgscppssecg.qdvpsniyke.....GCkekllewlrenllivagvgig
++s+p+++ + +++p n y + +++GC +++ e ++++l +++gv+++
F33C8.3 209 KLSYPNNCGRSfSQAPLNTYAQfintrGCADAVYESVSSSLSLIVGVCVV 258
iaviq<-*
++++q
F33C8.3 259 LCIVQ 263
TB: domain 1 of 1, from 258 to 276: score 8.6, E = 0.35
*->grCsnplpgravTKseCCC<-*
C ++l g++++++ CCC
F33C8.3 258 VLCIVQLLGIVLSMTLCCC 276