Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/F32F2.1
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Query: F32F2.1 CE18658 Guanine nucleotide exchange factor for Rho\/Rac\/Cdc42-like GTPases status:Partially_confirmed TR:Q9XXM9 protein_id:C
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
RhoGEF RhoGEF domain 81.2 1.4e-22 1
PH PH domain 17.0 0.0023 1
Rota_NS6 Rotavirus non-structural protein 6 4.4 6.3 1
Ribosomal_S19e Ribosomal protein S19e 3.3 7.9 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
Ribosomal_S19e 1/1 224 236 .. 133 145 .] 3.3 7.9
Rota_NS6 1/1 360 382 .. 1 23 [. 4.4 6.3
RhoGEF 1/1 227 405 .. 1 207 [] 81.2 1.4e-22
PH 1/1 498 535 .. 52 85 .] 17.0 0.0023
Alignments of top-scoring domains:
Ribosomal_S19e: domain 1 of 1, from 224 to 236: score 3.3, E = 7.9
*->LDrIAgqvldede<-*
LDrIA ++ld+++
F32F2.1 224 LDRIAIELLDTER 236
Rota_NS6: domain 1 of 1, from 360 to 382: score 4.4, E = 6.3
*->mnrLqqRqlFLEnLLvGvnstFH<-*
+ r+++ lFLEn+L + st H
F32F2.1 360 VQRILKYHLFLENILKNMPSTTH 382
RhoGEF: domain 1 of 1, from 227 to 405: score 81.2, E = 1.4e-22
*->vlkElleTEkkYvrdLeildnvymkpLreaaisskpvltpddietiF
+++Ell TE++Yv+dL +++++ym L+e k +t d i+++F
F32F2.1 227 IAIELLDTERTYVEDLNAVIKGYMDFLVEDR--EKLKVTLDAISSLF 271
sNiediyefhreFLkssLearisssqfedlDekkiepsaqrlGdlFlklk
++ie i f+++++ L+a+ + + +F ++
F32F2.1 272 GCIERIFAFNKQLYN-QLDAADLD--------------CVKMSRCFVES- 305
epflqvYgeYcsnkpyAqelleklrqaasnpqFaefldeveassntgAkd
+ ++ Y eYc+n+ + + +l + +++p +a+ l+e+++ ++
F32F2.1 306 SGKFEDYIEYCTNYHRMMSTLYH---LQQQPLVARALQERQLA-LNH--- 348
davkltLqsLLlkPvqRilrYpLLLkeLLkhtpegedqpdredLkkaldl
l L+++LlkPvqRil+Y+L+L +Lk p+ + ++ + k a +
F32F2.1 349 ---SLQLSAYLLKPVQRILKYHLFLENILKNMPSTTHPEELIQVKRAHEV 395
lqdlaksiNe<-*
+ a +iN+
F32F2.1 396 MTSQAARIND 405
PH: domain 1 of 1, from 498 to 535: score 17.0, E = 0.0023
*->kncFeirt.dr...tlllqaeseeerkeWvkaiqsair<-*
+ +F++ + d+++ +++++a+s e++++W++ +++ +
F32F2.1 498 PLSFQVLSfDNpraQYVFMASSMEQKRTWMQELKRMML 535