Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/F15B9.4
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Query:  F15B9.4  CE30954    status:Partially_confirmed TN:CAB01425 protein_id:CAB01425.2

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
FH2      Formin Homology 2 Domain                       350.9   1.3e-101   1
DUF252   Putative tyrosine phosphatase family             7.1       0.46   1
HNF-1A_C Hepatocyte nuclear factor 1 (HNF-1), alpha i     5.5        1.6   1
PAX      'Paired box' domain                              3.0        9.8   1
RTX      RTX N-terminal domain                            1.4        4.3   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
HNF-1A_C   1/1     114   124 ..     1    11 [.     5.5      1.6
DUF252     1/1     624   675 ..    31   101 ..     7.1     0.46
RTX        1/1     815   850 ..     1    38 [.     1.4      4.3
FH2        1/1     305   905 ..    24   486 .]   350.9 1.3e-101
PAX        1/1     952   966 ..   111   125 .]     3.0      9.8

Alignments of top-scoring domains:
HNF-1A_C: domain 1 of 1, from 114 to 124: score 5.5, E = 1.6
                   *->vlTsDpeahtD<-*
                      vlT D+e++tD
     F15B9.4   114    VLTKDSETQTD    124

DUF252: domain 1 of 1, from 624 to 675: score 7.1, E = 0.46
                   *->LrstLrLktIisLspEpypqdnlqeKFlesehIklyhiamegnkdpd
                      +++ LrL+ ++ +s E+ + +     F     I+l++ +++ +++
     F15B9.4   624    NKH-LRLRIELFISKENVTAEIGK--F--QSQIELLQTGCQLARG-- 663

                   ddkikikknpfvnipshllrraLk<-*
                               +i++ llr++L+
     F15B9.4   664 ------------EIVQVLLRKCLQ    675

RTX: domain 1 of 1, from 815 to 850: score 1.4, E = 4.3
                   *->tlaniKsqlkqglkstknklksagssaKeaLkkAgssl<-*
                      tl+ i ++l+q+ k + +  k+a+  +K+ L+ A+s +
     F15B9.4   815    TLQAIFETLEQSMKIVSDAVKQAA--TKNRLTRASSLV    850

FH2: domain 1 of 1, from 305 to 905: score 350.9, E = 1.3e-101
                   *->ad.aP..........................................
                      a+++P+++++  +  +++ +++++ ++ +++ ++++++++  +  +
     F15B9.4   305    APpPPgppssllplintnapppppmpsinghapnppppppllgiapm 351

                   ..................................................
                   +++ +++++ ++  + +++ ++++++++ +  +++++++++ + +  ++
     F15B9.4   352 stnapppppmpgmaplstgaptppppppvgmanggpppppplpldllkga 401

                   ..................................................
                     + ++ ++++++++++++++   +++ ++  ++++++++  +++  ++
     F15B9.4   402 vaglksvpggppppppppppsfmfngkvpnafspgtstspvlspgvvksa 451

                   ........................PdeksqktvWgttlddeieetklLen
                      ++++++   + ++ + + ++ + ++++  ++   +d+  +e +   +
     F15B9.4   452 vvyrkqkktafvrwpkltmqmqdaGTVFND-SLC---VDFNEDERTK--M 495

                   egllde.....lEelFamkektkkakkalsekksk....lmkkkvsknfk
                   e +++e + ++l +++ + ++++ + k+l  ++s+++ ++m++++++n++
     F15B9.4   496 EEVFEEapvkqLNRKI-AGSVGRAFGKSLRATTSSsefnPMSARSPTNPQ 544

                   ildpkrsqnppleIllrslhCdmsfeetvivvailevDevdvlsedllen
                   +l+++++++  +eIl+++l+ +m+f++  ++++++++D+ + +++dl+++
     F15B9.4   545 VLVSPKALT--IEILIKKLK-PMEFTQ--LIEKLDANDT-EGIKVDLMTT 588

                   LlkfaPYskteeelkklreykedkekdleeLsradqiFlllisnLipyle
                   L++++P   ++ el+++++++++     ++++ +dq F+++i++ +++l+
     F15B9.4   589 LNNNFP---DKVELDPFLKVEYA-----TLTHASDQ-FCWHIAR-NKHLR 628

                   eRmnallfksnfeeevedLkpkiekvtaAseeLreSkkfkklLeliLaiG
                    R++ ++ k+n++ e+ +++ +ie++++ ++  r  + ++ lL+ +L++G
     F15B9.4   629 LRIELFISKENVTAEIGKFQSQIELLQTGCQLAR-GEIVQVLLRKCLQYG 677

                   NYMNagsrrRgqAkGFkLssLlkLldtKsadnk..tTLLHyivkiirkky
                   NY N+gs++ ++A GF++s+L++Ll++K++ ++++++L+++iv ++++ +
     F15B9.4   678 NYLNQGSMF-AEAAGFQFSYLIQLLQMKGKGQHtsVRLVDLIVAYCDLAT 726

                   pdllnFeddlhhvdkaSsrkvnleqlekdvkslgrqiknlEtsldkgkLs
                   ++++++++++++v+     ++nl++le++v++++r         +++kL+
     F15B9.4   727 AEVEEVQSRMGSVR-----PLNLKDLEDVVGQVQR---------SIRKLE 762

                   dpe.fhpdDkflevmspflkaakekfdkLqkdlkdmktllenlveyygEd
                   ++ +++++++++++++pf+++++ek++++q+ l+d+k + ++l++y++
     F15B9.4   763 GQLrSSSEETLIAAYEPFVNQTNEKLQNVQNGLSDLKARETELQVYLCAG 812

                   pkddlspneFFkrfneflkefkkAvkeNekkekeeelrrrrkla.kekae
                   +   ++ + +F+++++++k+ ++Avk+        ++++r ++a+++++
     F15B9.4   813 N---MTLQAIFETLEQSMKIVSDAVKQA-------ATKNRLTRAsSLVTL 852

                   keqskskqke......knplmdfeae..pverdfkgvldsalleklrtga
                   +++s+s++++++++   +++m++++++ pve+++k++l+s  + ++r+++
     F15B9.4   853 PTSSVSRRSLregevlSRQSMALKTRdlPVEELKKMFLHS-SFGPQRAKR 901

                   afrr<-*
                   + ++
     F15B9.4   902 SVAS    905

PAX: domain 1 of 1, from 952 to 966: score 3.0, E = 9.8
                   *->kdnvPsvssisRilR<-*
                      +++ Psvs+i R +R
     F15B9.4   952    QQEPPSVSAIRRDIR    966



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