Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/E03H4.10
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Query:  E03H4.10  CE20647   C-type lectin domain status:Partially_confirmed TR:O17741 protein_id:CAB04034.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
CUB      CUB domain                                      90.8    1.8e-25   1
lectin_c Lectin C-type domain                            66.7    4.8e-16   2
Cdc37    Cdc37 family                                     2.2        8.3   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
Cdc37      1/1     146   153 ..   314   321 .]     2.2      8.3
lectin_c   1/2      41   153 ..     1   125 []    22.4  0.00022
lectin_c   2/2     175   281 ..     1   125 []    47.4  6.9e-11
CUB        1/1     305   409 ..     1   116 []    90.8  1.8e-25

Alignments of top-scoring domains:
Cdc37: domain 1 of 1, from 146 to 153: score 2.2, E = 8.3
                   *->lmqYileL<-*
                      lm+Yi+eL
    E03H4.10   146    LMSYICEL    153

lectin_c: domain 1 of 2, from 41 to 153: score 22.4, E = 0.00022
                   *->esktWaeAelaCqkegghAHLvsIqsaeEqsfvvafltsltkk.snt
                      ++ + + Ae  C + g++  Lv++ +         ++  ++ ++s
    E03H4.10    41    TKVNHTSAESSCNSFGAT--LVTVKNVNDE----QAIATVVAAsSAR 81

                   yaWIGLtdinte..gtwvwegwetdgspvnytenWapgePnnrgnhGgnE
                    +W+GL ++  +++ ++ w +   +gs  +y+ n + + P    +
    E03H4.10    82 LIWLGL-YCFDSdpAKCLWDD--NSGSAQSYD-NFSIDFPLVDAG----- 122

                   dCveiytdtdflaGkWnDepCdskl.pyvCef<-*
                   +Cv ++t  + laGkW +e+C+skl  y+Ce
    E03H4.10   123 HCVYLSTL-GALAGKWISEDCESKLmSYICEL    153

lectin_c: domain 2 of 2, from 175 to 281: score 47.4, E = 6.9e-11
                   *->esktWaeAelaCqkegghAHLvsIqsaeEqsfvvafltsltkksnty
                      ++ ++  A++ C + +g+  LvsI+s+ E+    +++  ++   ++y
    E03H4.10   175    TAEPFIIAQTKCAETYGD--LVSIHSSNEN----RYIETFAA--QDY 213

                   aWIGLtdintegtwvwegwetdgspvnytenWapgePnnrgnhGgnEdCv
                   + IG    + +++ +w     d+s ++y    ++++ n +++    ++Cv
    E03H4.10   214 YLIGAV-WKLDNSLYW----LDKSKWDYN---NTDPENSYRG----DYCV 251

                   eiytdtdfl..aGkWnDepCdsklpyvCef<-*
                   +++t +++  ++G W + +C  + +y+C++
    E03H4.10   252 AMSTVISSPipSGFWFSTNCTRPAKYICKR    281

CUB: domain 1 of 1, from 305 to 409: score 90.8, E = 1.8e-25
                   *->CGgtldltessGsisSPnYPnrsdYppnkeCvWrIrappgyrvVeLt
                      C     l  s+G+i+SPnYP+  +Y +n +C++++++   y+ + L+
    E03H4.10   305    CNAG--LLMSPGVITSPNYPE--NYFNNENCTYQLSTLGAYK-IALR 346

                   FqdFdlEdhdgaCryDyvEirDGdpssspllGrfCGsgkPedirStsnrm
                   F +F +E      + D+v ++DG+  +sp l r  G + P  ++S++n+m
    E03H4.10   347 FASFSTE------ANDVVTVYDGLTTDSPCLRRCSGTQRPFALTSSGNTM 390

                   likFvsDasvskrGFkAty<-*
                   l++F+sD+   ++GF+A++
    E03H4.10   391 LVTFTSDSKGISSGFYARF    409



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