Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/D2096.11
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Query:  D2096.11  CE31461    status:Partially_confirmed TR:Q19011 protein_id:AAA81498.3

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
GAS2     Growth-Arrest-Specific Protein 2 Domain        169.5      4e-49   1
CH       Calponin homology (CH) domain                  128.8      1e-34   3
CENP-B_N CENP-B N-terminal DNA-binding domain             8.1       0.98   1
ras      Ras family                                       5.8        1.2   1
spectrin Spectrin repeat                                  4.5        8.9   3
Guanylin Guanylin precursor                               2.2        2.8   1
V1R      Vomeronasal organ pheromone receptor family,     2.2          8   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
ras        1/1      40    77 ..    80   116 ..     5.8      1.2
CH         1/3      75   139 ..    50   106 .]    50.0    2e-12
spectrin   1/3     232   263 ..    77   108 .]     1.0       82
CH         2/3     260   325 ..    48   106 .]    30.1  6.6e-07
spectrin   2/3     410   449 ..    68   108 .]     1.6       55
CH         3/3     446   511 ..    48   106 .]    49.6  2.6e-12
Guanylin   1/1     537   552 ..    92   107 ..     2.2      2.8
spectrin   3/3     596   635 ..    68   108 .]     1.8       48
V1R        1/1     687   695 ..   257   265 .]     2.2        8
GAS2       1/1     650   722 ..     1    75 []   169.5    4e-49
CENP-B_N   1/1     847   858 ..     1    12 [.     8.1     0.98

Alignments of top-scoring domains:
ras: domain 1 of 1, from 40 to 77: score 5.8, E = 1.2
                   *->DITsrdSFenvk.kWleeilrhad.kdenvpivLVGNKc<-*
                      ++T++++ + +++kWl+ i++  ++++e +p++LVGNK+
    D2096.11    40    SVTDESTVDGIQtKWLPLIHQPFGdYHE-TPVILVGNKV    77

CH: domain 1 of 3, from 75 to 139: score 50.0, E = 2e-12
                   *->nklr..............eNlnlaldaaekeGlgivlvlldpeDive
                      nk+ ++ ++ ++++ +++e+ln+a+ aa++e +g+  +lld+eD+
    D2096.11    75    NKVGngfgeinsdsvsntERLNIAFAAADRE-FGV-ERLLDAEDVD- 118

                   aegnpdPDeklvltylwqLirrfq<-*
                      n+ PDek+++ty+++L+++ +
    D2096.11   119 --TNN-PDEKSIITYVSSLYNALP    139

spectrin: domain 1 of 3, from 232 to 263: score 1.0, E = 82
                   *->dseeikerleeLnerWeaLlelaaeRrqkLee<-*
                      d++e+ + ++++++++ ++ el+ +++ + ++
    D2096.11   232    DAKELDSLMKHVEDAYSDVFELISDKEGLIDR    263

CH: domain 2 of 3, from 260 to 325: score 30.1, E = 6.6e-07
                   *->Llnklr............eNlnlaldaaekeGlgivlvlldpeDive
                      L++++  ++ ++++ +++e lnla+ aa+ e +g   +lld+eD+
    D2096.11   260    LIDRFNasninsdsvpntESLNLAFAAADPE-FGA-GRLLDAEDVDT 304

                   aegnpdPDeklvltylwqLirrfq<-*
                     +n+ PDek v+ty+++L ++ q
    D2096.11   305 --NNN-PDEKPVITYVSSLNNAPQ    325

spectrin: domain 2 of 3, from 410 to 449: score 1.6, E = 55
                   *->LieegeahpdseeikerleeLnerWeaLlelaaeRrqkLee<-*
                      ++++g+   d++e+ + l+++++++ ++ el+ +++ + ++
    D2096.11   410    MKTAGP-EADTKELDSLLKQVEDAYSDVFELISDKEGLIDR    449

CH: domain 3 of 3, from 446 to 511: score 49.6, E = 2.6e-12
                   *->Llnklr............eNlnlaldaaekeGlgivlvlldpeDive
                      L++++  ++ ++++ +++e+ln+al aa+ e +g   +lld+eD+
    D2096.11   446    LIDRCNasninsdsvsntERLNIALAAADAE-FGA-GRLLDAEDVDT 490

                   aegnpdPDeklvltylwqLirrfq<-*
                     +n+ PDek+++ty+++L ++f+
    D2096.11   491 --NNN-PDEKSIITYVSSLNNAFP    511

Guanylin: domain 1 of 1, from 537 to 552: score 2.2, E = 2.8
                   *->eAasIlqaLrtIaqDd<-*
                      +A  I++aL++I++D+
    D2096.11   537    DADHIFKALEEISKDE    552

spectrin: domain 3 of 3, from 596 to 635: score 1.8, E = 48
                   *->LieegeahpdseeikerleeLnerWeaLlelaaeRrqkLee<-*
                      +++ g+   d++e+ + ++++++++ ++ el+ +++ + ++
    D2096.11   596    MKTVGP-ESDAKELDSLMKHVEDAYSDVVELISDKEGLIDR    635

V1R: domain 1 of 1, from 687 to 695: score 2.2, E = 8
                   *->KrIikflrS<-*
                      Kr++++lrS
    D2096.11   687    KRMVRILRS    695

GAS2: domain 1 of 1, from 650 to 722: score 169.5, E = 4e-49
                   *->dklddeVkrivedPPCkCpnkFqvekvSEGkYRfGDsqiLrlVRiLR
                      +k++ e+++++e+  C+C++++q+ek+SE+ YRfGD++i+r+VRiLR
    D2096.11   650    EKITNEIELLKET--CSCCTPYQIEKISENYYRFGDTHIKRMVRILR 694

                   StVMVRVGGGWetLdefLlKhDPCRakg<-*
                   StVMVRVGGGWe L+e L+KhDPCR kg
    D2096.11   695 STVMVRVGGGWEPLEESLQKHDPCRTKG    722

	[output cut off at A = 10 top alignments]


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