Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm2/seq/C54D1.1
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Query:  C54D1.1  CE04268  locus:pgp-10 multidrug-resistance protein status:Partially_confirmed TR:Q18824 protein_id:AAC48149.1

Scores for sequence family classification (score includes all domains):
Model         Description                               Score    E-value  N
--------      -----------                               -----    ------- ---
ABC_tran      ABC transporter                           387.6   1.3e-112   2
ABC_membrane  ABC transporter transmembrane region       75.8    8.8e-19   2
SKI           Shikimate kinase                           15.5     0.0029   2
PRK           Phosphoribulokinase / Uridine kinase fa    12.3      0.018   2
ras           Ras family                                  9.3       0.11   1
M             M protein repeat                            9.1       0.94   1
ATP-bind      Conserved hypothetical ATP binding prot     8.0       0.23   2
AIG1          AIG1 family                                 6.2        1.5   1
DUF232        Putative transcriptional regulator          5.7        4.2   1
CoaE          Dephospho-CoA kinase                        5.5        1.2   3
DNA_pol3_beta DNA polymerase III beta subunit, N-term     5.0        5.8   1
CbiA          Cobyrinic acid a,c-diamide synthase         4.6        2.7   1
AAA           ATPase family associated with various c     4.2        3.2   1
MobB          Molybdopterin guanine dinucleotide synt     3.4        9.4   3
DUF87         Domain of unknown function DUF87            3.2        6.9   1
Pox_A32       Poxvirus A32 protein                        3.1          8   1
IstB          IstB-like ATP binding protein               3.0        8.7   1

Parsed for domains:
Model         Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------      ------- ----- -----    ----- -----      -----  -------
ABC_membrane    1/2      97   216 ..     1   112 [.    11.4    0.093
M               1/1     217   237 ..     1    21 []     9.1     0.94
Pox_A32         1/1     381   394 ..    16    29 ..     3.1        8
MobB            1/3     381   394 ..     1    16 [.     2.9       13
ras             1/1     380   395 ..     1    16 [.     9.3     0.11
CoaE            1/3     381   398 ..     1    20 [.    -0.6       87
PRK             1/2     381   398 ..     1    19 [.     8.8     0.18
DUF87           1/1     381   400 ..   170   189 ..     3.2      6.9
CbiA            1/1     380   400 ..     1    22 [.     4.6      2.7
SKI             1/2     379   403 ..     1    30 [.     6.5      1.1
ATP-bind        1/2     380   406 ..     1    27 [.     6.9     0.51
ABC_tran        1/2     378   562 ..     1   199 []   206.7    1e-58
DUF232          1/1     586   603 ..     1    18 [.     5.7      4.2
MobB            2/3     822   847 ..   129   154 .]     0.3       74
CoaE            2/3     890   914 ..   164   186 .]     3.6      4.7
ABC_membrane    2/2     718   996 ..     1   285 []    70.9  2.5e-17
DNA_pol3_beta   1/1    1050  1069 ..    22    42 ..     5.0      5.8
IstB            1/1    1065  1082 ..    46    63 ..     3.0      8.7
ATP-bind        2/2    1070  1083 ..     1    14 [.     1.0       31
AIG1            1/1    1069  1083 ..     1    15 [.     6.2      1.5
AAA             1/1    1070  1084 ..     1    15 [.     4.2      3.2
SKI             2/2    1069  1084 ..     1    16 [.     9.0     0.22
MobB            3/3    1071  1085 ..     1    17 [.     0.0       86
PRK             2/2    1071  1088 ..     1    19 [.     9.1     0.15
CoaE            3/3    1071  1089 ..     1    21 [.     1.7       17
ABC_tran        2/2    1068  1258 ..     1   199 []   181.2  2.6e-51

Alignments of top-scoring domains:
ABC_membrane: domain 1 of 2, from 97 to 216: score 11.4, E = 0.093
                   *->lliailllilagatalvtfplllgrlldsgfplsdgnddharsslis
                      + +++++++l+ a+ ++   l++g ++++    +      +++ l
     C54D1.1    97    MAMGLFSALLQSALPPF-VWLIMGNFVSI---SILR----EEGKLGL 135

                   lails..................lfavfvliglllqgsfyllagerlgqr
                     ++s+ + +++  ++ ++   +++++ ++ ++ ++++ +    e+ ++r
     C54D1.1   136 KNLTSdypiddqfahsatpafisMLGLSIAMFIAAFCQRIA--WEISSIR 183

                   lrkrlfrallrqilglfdsffdtnsvGeltsRl<-*
                    + r+ +a++r++l ++ s+++ +++G   ++l
     C54D1.1   184 QVFRIKKAYIRKLLLMDISWLESRQSGHVAAML    216

M: domain 1 of 1, from 217 to 237: score 9.1, E = 0.94
                   *->eaKKeLEaelqeLeeelqkLe<-*
                      ++ ++L ae+++L+ee  +++
     C54D1.1   217    QEFEKLSAEHSKLTEERLRSS    237

Pox_A32: domain 1 of 1, from 381 to 394: score 3.1, E = 8
                   *->MaivGgsGSGKTty<-*
                      +aivG+sGSGK t+
     C54D1.1   381    IAIVGSSGSGKSTL    394

MobB: domain 1 of 3, from 381 to 394: score 2.9, E = 13
                   *->kIvqiVGykdSGKTTL<-*
                        ++iVG ++SGK TL
     C54D1.1   381    --IAIVGSSGSGKSTL    394

ras: domain 1 of 1, from 380 to 395: score 9.3, E = 0.11
                   *->KlVliGDsGVGKSsLl<-*
                      K+ ++G sG GKS+L+
     C54D1.1   380    KIAIVGSSGSGKSTLT    395

CoaE: domain 1 of 3, from 381 to 398: score -0.6, E = 87
                   *->lvvGLTGGIGSGKSTvAnlF<-*
                        +++ G +GSGKST+++l+
     C54D1.1   381    --IAIVGSSGSGKSTLTALL    398

PRK: domain 1 of 2, from 381 to 398: score 8.8, E = 0.18
                   *->vIGvaGsSGaGKTtvarri<-*
                       I++ GsSG+GK+t ++ +
     C54D1.1   381    -IAIVGSSGSGKSTLTALL    398

DUF87: domain 1 of 1, from 381 to 400: score 3.2, E = 6.9
                   *->fAvLAvTGaGKSNtVaVlir<-*
                      +A+ + +G+GKS+++a+l+r
     C54D1.1   381    IAIVGSSGSGKSTLTALLLR    400

CbiA: domain 1 of 1, from 380 to 400: score 4.6, E = 2.7
                   *->rlmvaGTgSgvGKTtltagLcr<-*
                       + ++G +Sg+GK+tlta L+r
     C54D1.1   380    KIAIVG-SSGSGKSTLTALLLR    400

SKI: domain 1 of 2, from 379 to 403: score 6.5, E = 1.1
                   *->rnifLIGmmGaGKsTvGrlLAkaLgreFvD<-*
                      ++i ++G  G+GKsT+      aL ++F+D
     C54D1.1   379    EKIAIVGSSGSGKSTL-----TALLLRFYD    403

	[output cut off at A = 10 top alignments]


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