Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm2/seq/C53B4.4b
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Query: C53B4.4b CE20600 PDZ domain (Also known as DHR or GLGF). \; Phorbol esters\/diacylglycerol binding domain (C1 domain) status:Partially
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
PDZ PDZ domain (Also known as DHR or GLGF) 32.8 7.1e-08 1
DAG_PE-bind Phorbol esters/diacylglycerol binding dom 11.3 0.3 1
Pep3_Vps18 Pep3/Vps18/deep orange family 5.3 2.8 1
DUF114 Protein of unknown function DUF114 2.4 5 1
zf-C3HC4 Zinc finger, C3HC4 type (RING finger) 2.2 7.5 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
PDZ 1/1 501 586 .. 1 84 [] 32.8 7.1e-08
DUF114 1/1 620 647 .. 1 28 [. 2.4 5
Pep3_Vps18 1/1 782 800 .. 154 172 .] 5.3 2.8
zf-C3HC4 1/1 1223 1234 .. 38 50 .] 2.2 7.5
DAG_PE-bind 1/1 1218 1258 .. 1 44 [. 11.3 0.3
Alignments of top-scoring domains:
PDZ: domain 1 of 1, from 501 to 586: score 32.8, E = 7.1e-08
*->evtlekevkrgglGfsikggsdk.......givvsevlpGsgaAeag
++t+ +++ ++++G+ + +++++++++ + v+ v +s a++a+
C53B4.4b 501 LLTFSRYDVSSPIGLVFDKNVAAtgnntnrAVKVCTVEDNSLADKAA 547
GrLkeGDvIlsvNGqdvenmsheravlaikgsggsevtLtvlRd<-*
k+GDv++++N+++++ s+ +a +++++ g +t++v+R
C53B4.4b 548 --FKPGDVLVAINNVPIR--SERQATRFLQSTTG-DLTVLVERS 586
DUF114: domain 1 of 1, from 620 to 647: score 2.4, E = 5
*->keysDplssflssLlwfLLffyLilaPq<-*
+ pl+ f +s ++fL L ++P+
C53B4.4b 620 TILTKPLTTFHFSVFYFLVSHHLYFYPE 647
Pep3_Vps18: domain 1 of 1, from 782 to 800: score 5.3, E = 2.8
*->epsqrdlVllksAdflfqd<-*
+++++d+Vl +sAdf ++
C53B4.4b 782 DAKVIDAVLSSSADFGMEN 800
zf-C3HC4: domain 1 of 1, from 1223 to 1234: score 2.2, E = 7.5
*->Wls.gnttvkCplC<-*
W+ +++tt C +C
C53B4.4b 1223 WYGkNSTT--CAMC 1234
DAG_PE-bind: domain 1 of 1, from 1218 to 1258: score 11.3, E = 0.3
*->HrFkrttfyksptfCdhCgellwglakQGlkCsnCglnvHkrCh<-*
H++k k+ t C+ C+ +w + Cs C + +H +C+
C53B4.4b 1218 HDWKLWYG-KNSTTCAMCRGKIWL--RNASSCSRCLVICHNKCV 1258