Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C42D8.5
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Query:  C42D8.5  CE30627   peptidase status:Partially_confirmed TR:Q18581 protein_id:AAA98719.2

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
Peptidase_M2 Angiotensin-converting enzyme              153.9    2.8e-42   2
EB           EB module                                   12.1       0.15   1
PLRV_ORF5    Potato leaf roll virus readthrough prote     1.0        9.7   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
PLRV_ORF5      1/1      65    94 ..     1    30 [.     1.0      9.7
Peptidase_M2   1/2     332   646 ..   171   472 ..   105.3  1.2e-27
Peptidase_M2   2/2     709   770 ..   544   606 .]    48.3  8.9e-11
EB             1/1     796   824 ..    20    52 ..    12.1     0.15

Alignments of top-scoring domains:
PLRV_ORF5: domain 1 of 1, from 65 to 94: score 1.0, E = 9.7
                   *->VDgsPaPePgPsPtPtPtPqPtPqPqPePv<-*
                      ++++P PeP+P P P P P P P+P PeP+
     C42D8.5    65    PEPEPKPEPEPEPEPKPEPEPSPTPEPEPA    94

Peptidase_M2: domain 1 of 2, from 332 to 646: score 105.3, E = 1.2e-27
                   *->kplfpeYveLsnkAarlnGyrDaGdyWrslYEsP........tfEqd
                      kp +   + +sn+ a+lnG+   G+ Wrs ++  ++ ++ + ++ ++
     C42D8.5   332    KPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSskvhkaefDLNKQ 378

                   LErlfqqLePLYlnLHAYVRraLhrhYGddy.iNLeGPIPahLLGNMWAQ
                    ++++   +P Y  LHAY Rr L   Y   ++   +GPIPahL G   +
     C42D8.5   379 IDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVgLSKDGPIPAHLFGSLDGG 428

                   sWeniYDLvvPFPdkPnlDvteaMi....kqGWtarrmFrvadeFFtSLG
                    W+  Y    PF + +   + eaM++  + q +t ++mF  a  +F S G
     C42D8.5   429 DWSAHYEQTKPFEEESE--TPEAMLsafnTQNYTTKKMFVTAYRYFKSAG 476

                   LlPlPPeFWnkSmLeKPtDGReVVCH.ASAWDFYngkDfRIKqCTeVnme
                      lP ++W  S+  +     + +CH+A A D     DfR+K C +
     C42D8.5   477 FPHLPKSYWTSSIFARVWS-KDMICHpAAALDMRAPNDFRVKACAQLGEP 525

                   dLvvVHHEmGHIQYYLQ..YkDlPVslRegANPGFHEAIGDVlALSVsTP
                   d+  +H  +  +Q Y Q  YkD+   +Re A P    AI    A     P
     C42D8.5   526 DFEQAHSLL--VQTYYQylYKDQSLLFREQASPVITDAIANAFAHLSTNP 573

                   kHLhsIgLLdsegndeesd..INfLlKmALdKIaFlPFgYLVDqWRWrVF
                     L+s  L+ se +d++    IN L K  L+    lPF  + D WR+  F
     C42D8.5   574 HYLYSQKLVPSEHLDIKDSviINKLYKESLESFTKLPFTIAADNWRYELF 623

                   dGsitksrYNqeWWsLRlkYQGl<-*
                   dG ++k + N  WW +R kY G+
     C42D8.5   624 DGTVPKNKLNDRWWEIRNKYEGV    646

Peptidase_M2: domain 2 of 2, from 709 to 770: score 48.3, E = 8.9e-11
                   *->kLaqvLklGySRPWkEvLkditGqdnmdAsALLeYFkPltqWLkeeN
                      kL++ +klG+S  W  +L+ i G+ ++dA++LLeY++Pl+ WL+  N
     C42D8.5   709    KLRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTN 755

                   erhGevLGWPeYqWrP<-*
                   e   +v GW + + +P
     C42D8.5   756 EIDQVVVGW-DGEGTP    770

EB: domain 1 of 1, from 796 to 824: score 12.1, E = 0.15
                   *->vnpGesgCeaseQCqggwpgSvCingmCeCpeg<-*
                      ++pG+  C+++++C      S+C   +C C +g
     C42D8.5   796    AFPGG-ECVNGQECLLD---SHCNGTICVCNDG    824



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