Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C37C3.2a
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Query:  C37C3.2a  CE27367    status:Confirmed TN:AAC25859 protein_id:AAC25859.2

Scores for sequence family classification (score includes all domains):
Model      Description                                  Score    E-value  N
--------   -----------                                  -----    ------- ---
eIF5_eIF2B Domain found in IF2B/IF5                     280.3    2.5e-80   1
W2         eIF4-gamma/eIF5/eIF2-epsilon                 126.7    3.6e-38   1

Parsed for domains:
Model      Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------   ------- ----- -----    ----- -----      -----  -------
eIF5_eIF2B   1/1       1   128 [.     1   138 []   280.3  2.5e-80
W2           1/1     295   380 ..     1    87 []   126.7  3.6e-38

Alignments of top-scoring domains:
eIF5_eIF2B: domain 1 of 1, from 1 to 128: score 280.3, E = 2.5e-80
                   *->rafnIeRekNpdrvvgdksFYRFemPppqvkiEGkGNGiKTiivNfs
                      +a       N++r v d +FYR++mP++++k+EGkGNGiKT+i+N+s
    C37C3.2a     1    MA------LNVNRAVAD-PFYRYKMPKLSAKVEGKGNGIKTVISNMS 40

                   DIAkaLnRppelhllKYLlaELGtaGsiDgkngRlivnGrftpkkLqdvL
                   +IAkaL+Rpp+ +++KY+++ELG+++++D+kn+R+ivnG+++++kLqd+L
    C37C3.2a    41 EIAKALERPPM-YPTKYFGCELGAQTNFDAKNERYIVNGEHDANKLQDIL 89

                   ddYIkeYVlCheCksPdTelikekkdRliflkCkACGarrp<-*
                   d++Ik++VlC++C++P+T+l+++  +++i  kCkACG++++
    C37C3.2a    90 DGFIKKFVLCKSCENPETQLFVR--KNNIKSKCKACGCSFD    128

W2: domain 1 of 1, from 295 to 380: score 126.7, E = 3.6e-38
                   *->eeeqidlLlaiEefcvkleeelvikllakiLkslYDaDileEeaIlk
                      +++q++lL+++E++++k+e+el +++ a+i+kslYD+D++eE++ ++
    C37C3.2a   295    KKAQRYLLGGVEQVIHKHEAEL-LSKSAHIIKSLYDEDVCEEDSLIS 340

                   WyekadsadeskEgkskvrkqakkFitWLkeAeEEEseee<-*
                   W+ek++s+++sk++++k+ ++ ++ ++WLkeAeEE +ee+
    C37C3.2a   341 WGEKPSSKYVSKSFAKKIIENSQPVLNWLKEAEEETEEES    380



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