Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C34F11.5
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Query: C34F11.5 CE04165 tyrosine-protein kinase status:Partially_confirmed TR:Q18462 protein_id:AAA85760.1
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
pkinase Protein kinase domain 138.4 1.2e-37 1
SH2 SH2 domain 23.0 1e-06 2
Arabinose_Isome L-arabinose isomerase 6.3 0.29 1
RMF Ribosome modulation factor 4.1 9.4 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
SH2 1/2 84 109 .. 1 28 [. 20.6 6.9e-06
SH2 2/2 153 164 .. 68 79 .] 2.4 14
Arabinose_Isome 1/1 397 410 .. 489 502 .] 6.3 0.29
pkinase 1/1 201 427 .. 7 263 .. 138.4 1.2e-37
RMF 1/1 779 789 .. 1 11 [. 4.1 9.4
Alignments of top-scoring domains:
SH2: domain 1 of 2, from 84 to 109: score 20.6, E = 6.9e-06
*->WyhGkIsRkeAErlLlnpggkdGtFLvR<-*
W++G I+ eAE +L+ ++G FLvR
C34F11.5 84 WFWGMITQTEAEGHLKD--CRHGEFLVR 109
SH2: domain 2 of 2, from 153 to 164: score 2.4, E = 14
*->kFssLpeLvehY<-*
++ +L +Lv +Y
C34F11.5 153 RHKTLVDLVAYY 164
Arabinose_Isome: domain 1 of 1, from 397 to 410: score 6.3, E = 0.29
*->deLkWNEvlYrlrk<-*
+eLkW E+l rl+
C34F11.5 397 HELKWKEALPRLQN 410
pkinase: domain 1 of 1, from 201 to 427: score 138.4, E = 1.2e-37
*->lGeGsfGkVykakhkdktgkiVAvKilkk.ekesikek.rflrEiqi
lG+G +G+V + ++ ++VA+K+l ++++ + +++ +l E+
C34F11.5 201 LGSGQYGCVAIGAYR---RRLVAIKKLTSsGERLLLDReALLKEAMF 244
lkrLsHpNIvrligvfedtddhlylvmEymegGdLfdylrrnggplseke
+++L+Hp+I ++ig+ ++++++l E+m + L+d+l++ g + + e
C34F11.5 245 MQKLQHPYITKIIGISI-DKTPPMLLIELMAC-PLLDHLQKYGKYTTIGE 292
akkialQilrGleYLHsngivHRDLKpeNILldendgtvKiaDFGLArll
+ + +Q++rGl+++ +++vHRD++++N+L++++ g vK++D GL+
C34F11.5 293 KLLYLWQLARGLSFMAKENVVHRDIAARNVLFSRH-GIVKVSDLGLSDYE 341
e..sssklttfvGTpwYmmAPEvileg...rgysskvDvWSlGviLyEll
++ ++++ + + +PE ++ ++++++ k DvW +G + E++
C34F11.5 342 SklQAVNTSKERLPRAWL-PPES-VSKtggNKFNEKTDVWMFGATSVEVF 389
tggplfpgadlpaftggdevdqliifvlklPfsdelpktridpleelfri
g ++P+++ +++e +
C34F11.5 390 QNG-------------------------QPPYHE-------LKWKEALPR 407
ikrp...glrlplpsncSee<-*
++++++++ +l +p++ S+e
C34F11.5 408 LQNFkdgDNLLVFPKYASSE 427
RMF: domain 1 of 1, from 779 to 789: score 4.1, E = 9.4
*->MkRqKRDrLER<-*
Mk qK DrL R
C34F11.5 779 MKKQKIDRLHR 789