Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C30F8.4a
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Query:  C30F8.4a  CE25798  locus:kin-32 protein kinase status:Partially_confirmed TR:Q95YD4 protein_id:AAK85457.1

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
pkinase      Protein kinase domain                      240.8      2e-68   1
DUF339       Domain of unknown function (DUF339)          5.1        4.5   1
W2           eIF4-gamma/eIF5/eIF2-epsilon                 4.3        4.4   1
MIF4G        MIF4G domain                                 4.1        4.4   1
Peptidase_C8 Peptidase family C8                          3.7        5.2   1
Pox_I1       Poxvirus protein I1                          2.5        7.5   1
Morbilli_P   Morbillivirus RNA polymerase alpha subun     2.3        9.5   1

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Peptidase_C8   1/1      32    44 ..     1    13 [.     3.7      5.2
MIF4G          1/1      91   112 ..   209   230 .]     4.1      4.4
DUF339         1/1     245   274 ..   108   138 .]     5.1      4.5
Pox_I1         1/1     257   281 ..   288   312 .]     2.5      7.5
Morbilli_P     1/1     347   358 ..   292   303 .]     2.3      9.5
pkinase        1/1     367   621 ..     1   290 [.   240.8    2e-68
W2             1/1     679   691 ..    74    87 .]     4.3      4.4

Alignments of top-scoring domains:
Peptidase_C8: domain 1 of 1, from 32 to 44: score 3.7, E = 5.2
                   *->lARaIGlStaave<-*
                       AR IG+S  av+
    C30F8.4a    32    VARGIGISQVAVA    44

MIF4G: domain 1 of 1, from 91 to 112: score 4.1, E = 4.4
                   *->epelssrirfmledlielrknk<-*
                      e +l++r+rfm ++++el++ +
    C30F8.4a    91    EIKLEMRMRFMPQSVYELQATD    112

DUF339: domain 1 of 1, from 245 to 274: score 5.1, E = 4.5
                   *->iaqsnlglmyklgrkfdlsemvallskirkn<-*
                      +++   gl y+l  ++d+s++++ l++i+++
    C30F8.4a   245    VVGPHTGLSYRLNERCDSSRLLE-LRTIAEI    274

Pox_I1: domain 1 of 1, from 257 to 281: score 2.5, E = 7.5
                   *->NEkinvskVVeyLtVstvkiesleE<-*
                      NE+ + s+  e  t+  ++i  +e
    C30F8.4a   257    NERCDSSRLLELRTIAEITIRKMEN    281

Morbilli_P: domain 1 of 1, from 347 to 358: score 2.3, E = 9.5
                   *->tasprsqNniEs<-*
                      t+ p+++Nni s
    C30F8.4a   347    TIRPKTPNNIDS    358

pkinase: domain 1 of 1, from 367 to 621: score 240.8, E = 2e-68
                   *->yelleklGeGsfGkVykakhkd...ktgkiVAvKilkkekesikek.
                      ++l+e +G G fG Vyka+++d +++    VAvK+ k     +++ +
    C30F8.4a   367    ITLKELIGGGQFGNVYKAVYHDlekDERIAVAVKVCK--TDAEPADt 411

                   .rflrEiqilkrLsHpNIvrligvfedtddhlylvmEymegGdLfdylrr
                   + +l E +++++++H NI++ligv+   d++++lv+E++++G+L++yl++
    C30F8.4a   412 qLILQESSLMRNFRHSNIIQLIGVCV--DQPMWLVLELAPKGELREYLQQ 459

                   nggplsekeakkialQilrGleYLHsngivHRDLKpeNILldendgtvKi
                   ++++l+ + +  +++Qi+  l YLHs ++vHRD++++NIL+ ++   vK+
    C30F8.4a   460 EKDWLPLRILTLFCSQICDSLVYLHSTRFVHRDIAARNILVCSP-QCVKL 508

                   aDFGLArlle.sssklttfvGTpwYmmAPEvilegrgysskvDvWSlGvi
                   aDFGL+r l+ + +++ +++  p  ++APE  +++r +s ++DvW +Gv
    C30F8.4a   509 ADFGLSRALDyDAVYTASRGKLPIKWLAPES-VNYRQFSMASDVWMFGVC 557

                   LyElltggplfpgadlpaftggdevdqliifvlklPfsdelpktridple
                   ++E+++ g                           P+ +        + +
    C30F8.4a   558 MWEIFSLG-------------------------VKPWAG-------VTNS 575

                   elfriikrpglrlplpsncSeelkdLlk.kcLnkDPskRpGsatakeiln
                    +  +i++ g r+p+p+ c+ +l+ ++++k+++  P+kRp   t  +i +
    C30F8.4a   576 DVIMHIEQ-GSRPPCPEKCPTALYNFIRsKMWAIEPHKRP---TVDQIYA 621

                   <-*

    C30F8.4a     -     -

W2: domain 1 of 1, from 679 to 691: score 4.3, E = 4.4
                   *->tWLkeAeEEEseee<-*
                      +WL e+e++E+e++
    C30F8.4a   679    KWL-EQEDDEDEDD    691



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