Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C27A7.5a
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Query:  C27A7.5a  CE20527   asparaginase status:Partially_confirmed TR:P90758 protein_id:CAB02791.1

Scores for sequence family classification (score includes all domains):
Model        Description                                Score    E-value  N
--------     -----------                                -----    ------- ---
Asparaginase Asparaginase                               191.5    1.8e-55   2
ank          Ankyrin repeat                              63.7    2.5e-16   4

Parsed for domains:
Model        Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------     ------- ----- -----    ----- -----      -----  -------
Asparaginase   1/2     126   136 ..     1    11 [.    -1.7  1.3e+02
Asparaginase   2/2     191   465 ..    42   327 .]   191.4    2e-55
ank            1/4     520   544 ..     9    33 .]     2.0       88
ank            2/4     545   577 ..     1    33 []    32.0  2.6e-07
ank            3/4     578   610 ..     1    33 []     0.2  2.9e+02
ank            4/4     644   676 ..     1    33 []    35.1  3.5e-08

Alignments of top-scoring domains:
Asparaginase: domain 1 of 2, from 126 to 136: score -1.7, E = 1.3e+02
                   *->TiAGtgasstn<-*
                      +++Gt++++t+
    C27A7.5a   126    YTGGTIGMKTT    136

Asparaginase: domain 2 of 2, from 191 to 465: score 191.4, E = 2e-55
                   *->iHeqllnidSsdmtpedllklakaVnellqdkdvdGvVITHGTDTlE
                      i e+ + +dS dmt++d+ ++a++++ ++ ++d  G+V++HGTDTl+
    C27A7.5a   191    IVEYEPLLDSCDMTFDDWIRIATDIKKAYHKYD--GFVVLHGTDTLA 235

                   ETAfFLdltvktadKPvVvtGsmrPatavsADGpaNLynAvavAadkasr
                   +TA++L+++ ++++KPv++tGs++P ++v++DG+ NL +A+ +A + ++
    C27A7.5a   236 YTASALSFMMENLGKPVIITGSQIPVAEVRSDGMENLIGALITAGNFDIP 285

                   grGVlVvfNdrilsgrdvtKtnassldaFdspnygyLGfisngkiyYsrt
                     +V V fN+ + +g++++K+ +s+l+aFdspn  +L+   ++ i +++
    C27A7.5a   286 --EVCVYFNNKLMRGNRTVKLDNSALEAFDSPNMHPLAQMAIN-IKVNYD 332

                   ptkphtsnsefdvskitesslPkVdIVyiyypdgdadalraalqagvkGI
                   +  +    + f v+   e+ + +V+ + i  p ++ +++ra+lq + +G
    C27A7.5a   333 SIFRSDMVAAFTVH---ENLCRDVGMLRIF-PSMTIESVRAFLQPPTRGC 378

                   VlagvGnGnvpnsviatlekaeel.esGvvVVrssrvmsGgvdvgirnae
                   +l + G+Gn+p + +++++ + e   +Gv VV+ s++  G   v  ++a
    C27A7.5a   379 ILQTFGSGNMPTRRQDIIMALKEAiARGVMVVNCSQCLKGQ--VDVNYAT 426

                   nkddkkkgavasgyLnPekAriLLmlALtq.tsdsksvIqr<-*
                   +k +   g++ + +++ e+A  +L ++L++++ d++   +r
    C27A7.5a   427 GKILYDIGVIPGSDMTSEAAMAKLCYVLGKdEWDLP--MKR    465

ank: domain 1 of 4, from 520 to 544: score 2.0, E = 88
                   *->AakrgnlevvklLlqrGAdlnaqdd<-*
                      Aak +++e++k L  +G +  a+d
    C27A7.5a   520    AAKTNDVEILKSLKAAGVNFSATDY    544

ank: domain 2 of 4, from 545 to 577: score 32.0, E = 2.6e-07
                   *->dGnTPLHlAakrgnlevvklLlqrGAdlnaqdd<-*
                      + +T+LH+Aa++g+le v +Ll+ G +++++d
    C27A7.5a   545    NLRTALHVAASNGHLESVNYLLKIGTNVHIKDM    577

ank: domain 3 of 4, from 578 to 610: score 0.2, E = 2.9e+02
                   *->dGnTPLHlAakrgnlevvklLlqrGAdlnaqdd<-*
                       G+ +L +A+k   ++++  + ++G  ++a
    C27A7.5a   578    FGYNALVCAVKAKAMDCIIAIRDAGGFIDASAQ    610

ank: domain 4 of 4, from 644 to 676: score 35.1, E = 3.5e-08
                   *->dGnTPLHlAakrgnlevvklLlqrGAdlnaqdd<-*
                      d +T+LH+Aa+ + +e+v++Llq+G +++ +dd
    C27A7.5a   644    DNRTALHVAASLNKPEIVAYLLQCGLNPHEKDD    676



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