Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C16C2.2b
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Query:  C16C2.2b  CE30491  locus:eat-16 regulator of G-protein signalling status:Confirmed TR:Q8T3F0 protein_id:CAD30433.1

Scores for sequence family classification (score includes all domains):
Model    Description                                    Score    E-value  N
-------- -----------                                    -----    ------- ---
RGS      Regulator of G protein signaling domain        104.1    4.4e-28   1
DEP      Domain found in Dishevelled, Egl-10, and Ple    89.8    5.5e-23   1
G-gamma  GGL domain                                      82.3    1.7e-25   1

Parsed for domains:
Model    Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
-------- ------- ----- -----    ----- -----      -----  -------
DEP        1/1      15    96 ..     1    82 []    89.8  5.5e-23
G-gamma    1/1     204   258 ..     1    55 []    82.3  1.7e-25
RGS        1/1     287   407 ..     1   146 []   104.1  4.4e-28

Alignments of top-scoring domains:
DEP: domain 1 of 1, from 15 to 96: score 89.8, E = 5.5e-23
                   *->pesgvklkdrkwllkvipncFtGselVdWLmdnlsgvidrkeAlhla
                       ++g +lk++k++ + +p++ tG++l+   ++++   +d++eA hla
    C16C2.2b    15    VMEGAQLKTHKYFRIAVPHAITGQQLIALVLERGA-PDDEAEASHLA 60

                   qlLlkeGyirhvgdh.ltgkndhtFldkqtyYrfpd<-*
                   +lLl++Gy+++v +h++ +k+d+t+++ q++Y++p+
    C16C2.2b    61 SLLLHHGYMFPVIEHgQPFKDDGTLYRLQRPYFWPS    96

G-gamma: domain 1 of 1, from 204 to 258: score 82.3, E = 1.7e-25
                   *->vdqlrkeveqLrkelsre.RiKvSkaaeellaYceqraenDPLltGp
                      ++ +r+++++Lr+++++++++K+ ka+++++++++qrae+DP+l++p
    C16C2.2b   204    AQGYRCLMDRLRFAIKTKpWLKALKASDTMVTWVDQRAEFDPFLHPP 250

                   ppskNPFie<-*
                   +ps NP+i+
    C16C2.2b   251 QPS-NPWIS    258

RGS: domain 1 of 1, from 287 to 407: score 104.1, E = 4.4e-28
                   *->sfeklldkqpiGrllFreFLetefsepkenleFwlaveeyektespa
                      s  +l  k+piGr ++  FLe+efs+  en++Fw+a+++++ +++
    C16C2.2b   287    SVQELV-KDPIGRQVLETFLESEFSS--ENIRFWIAIQDLKYAPN-- 328

                   dkrsdkarekesiEtLaaAYGIydeFispeapkfevnldselrestqdnl
                   +   +ka              I++eF++ +ap+ +vn+d ++ ++t + +
    C16C2.2b   329 EQIYQKAER------------IREEFLAQGAPA-QVNVDNRTLDQTLECI 365

                   leavededllksLqptkdlFeeaqreiytlMrgDSfprFLeSdyylrfL<
                   ++a       k+    +  F    ++++tlM++DS+prF +S +y++ L
    C16C2.2b   366 SKA-------KDASQMRFAFYHSEEHVFTLMAKDSYPRFVRSQIYKAVL  407

                   -*

    C16C2.2b     -    -



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