Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/C09D8.1a
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Query: C09D8.1a CE30244 locus:ptp-3 protein-tyrosine phosphatase with fibronectin type III-like domains (DPTP and LAR like) status:Partially_c
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
Y_phosphatase Protein-tyrosine phosphatase 787.5 5.2e-233 2
fn3 Fibronectin type III domain 331.0 1.3e-95 9
ig Immunoglobulin domain 63.0 8.8e-16 3
PKD PKD domain 7.9 0.26 2
Amino_oxidase Flavin containing amine oxidoreductase 4.9 1.8 1
MR_MLE_N Mandelate racemase / muconate lactonizi 4.6 2.7 1
cytochr_b558a Cytochrome Cytochrome b558 alpha-subuni 3.0 2.2 1
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
ig 1/3 62 124 .. 1 50 [] 21.4 0.00029
ig 2/3 165 227 .. 1 50 [] 20.4 0.00053
ig 3/3 265 320 .. 1 50 [] 21.1 0.00034
MR_MLE_N 1/1 325 357 .. 1 35 [. 4.6 2.7
fn3 1/9 339 424 .. 1 84 [] 53.2 6.5e-14
fn3 2/9 436 525 .. 1 84 [] 60.4 5.4e-16
PKD 1/2 508 530 .. 76 99 .] 2.9 10
fn3 3/9 537 618 .. 1 84 [] 67.0 7.1e-18
fn3 4/9 631 738 .. 1 84 [] 56.6 6.8e-15
fn3 5/9 750 843 .. 1 84 [] 62.9 1e-16
fn3 6/9 855 943 .. 1 84 [] 8.0 0.76
cytochr_b558a 1/1 936 969 .. 160 191 .] 3.0 2.2
fn3 7/9 973 1043 .. 17 84 .] 14.7 0.0088
PKD 2/2 1041 1078 .. 1 48 [. 6.5 0.71
fn3 8/9 1056 1147 .. 1 84 [] 31.2 1.4e-07
fn3 9/9 1158 1240 .. 1 73 [. 1.7 48
Amino_oxidase 1/1 1373 1390 .. 409 426 .] 4.9 1.8
Y_phosphatase 1/2 1650 1881 .. 1 274 [] 438.9 4.5e-128
Y_phosphatase 2/2 1938 2171 .. 1 274 [] 354.9 8.9e-103
Alignments of top-scoring domains:
ig: domain 1 of 3, from 62 to 124: score 21.4, E = 0.00029
*->GesvtLtCsvsgfgpp.p.vtWlrngk.le...........tsslsl
+ ++ C++ g+p p+v W+ ngk+++++++ + ++ t+ ++l
C09D8.1a 62 ESKISFFCRAD--GNPlPsVIWRVNGKsITdhnrisikslaTGLSTL 106
ti.svtpeDsgGtYtCvv<-*
++++v+ +D+ ++ +C +
C09D8.1a 107 RFeRVSLDDNATVVSCSA 124
ig: domain 2 of 3, from 165 to 227: score 20.4, E = 0.00053
*->GesvtLtCsvsgfgpp.p.vtWlrngk.le............tssls
G ++ +C+v+ g+p+++v Wlr+ +l + +++ + ++ +
C09D8.1a 165 GKTAYVSCRVR--GDPrAkVLWLRDLIpLDiradgrysvstiGNPGA 209
lti.svtpeDsgGtYtCvv<-*
l i+ +++eD G Y C +
C09D8.1a 210 LMIqHAREEDQ-GKYECIA 227
ig: domain 3 of 3, from 265 to 320: score 21.1, E = 0.00034
*->GesvtLtCsvsgfgpp.p.vtWlrngk.le.......tsslslti.s
G+ +LtC + g p p+v+W++ + + +++++ + + +lt++
C09D8.1a 265 GGNINLTCVAV--GYPmPrVFWKKTDLmVLddpstapIGKNVLTLtH 309
vtpeDsgGtYtCvv<-*
v++ ++tCv+
C09D8.1a 310 VESTE---NFTCVA 320
MR_MLE_N: domain 1 of 1, from 325 to 357: score 4.6, E = 2.7
*->mkIeaievfvvevattlrlPvqmavgTvqtqslVl<-*
Iea+++++++++++ +Pv + v +v s+V+
C09D8.1a 325 GNIEATTTVIAKELPP--PPVNIVVSSVTSESVVI 357
fn3: domain 1 of 9, from 339 to 424: score 53.2, E = 6.5e-14
*->PsaPtnltvtdvtstsltlsWspptgngpitgYevtyRqpkngge..
P++P n++v++vts s++++W+pp+ n i +Y v yR k +++++
C09D8.1a 339 PPPPVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYR-LKYSEGrs 384
..wneltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
++ ++ ++ ++ gL++ +Ye++V++ +G G eS
C09D8.1a 385 srGKTMETLENS--LVIDGLVAFQTYEFTVRSAGPVGvGLES 424
fn3: domain 2 of 9, from 436 to 525: score 60.4, E = 5.4e-16
*->P.saPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge
P aP +++++++ +s+ + W p +++ng itgY+v y ++
C09D8.1a 436 PaTAPVSPQARSLNRDSILVKWGPCEqPNGLITGYKVYY-TNDLVTT 481
....wneltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
+ ++w++ + ++++ t++gL+P+++Y vrV+A+n +G++p S
C09D8.1a 482 pireWKQHDAKSDEFMTTINGLEPDSRYFVRVIAQNSEGdSPLS 525
PKD: domain 1 of 2, from 508 to 530: score 2.9, E = 10
*->tYtVtLtvsNgvgsasattttvtV<-*
+Y V++ + N+ g + ++ t vtV
C09D8.1a 508 RYFVRVIAQNSEGDSPLS-TLVTV 530
fn3: domain 3 of 9, from 537 to 618: score 67.0, E = 7.1e-18
*->PsaPtnltvtdvtstsltlsWspptgngpitgYevtyRqpknggewn
P++P ltv+++ s ++l+W++p ++p+ gY+v+y +++g+ +
C09D8.1a 537 PGQPPMLTVKALDSRRMQLTWDKPLYSSPVVGYTVRY-NTSDGE--K 580
eltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-*
elt++++ +++tgL P+ Y +rV+A++++G+G+++
C09D8.1a 581 ELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGqGEFT 618
fn3: domain 4 of 9, from 631 to 738: score 56.6, E = 6.8e-15
*->PsaPtnltvtdvtstsltlsWsppt...gngpitgYevtyRqpkngg
+s Pt +++ +++s s+ ++W+ p++++ ng++t Y++ y +
C09D8.1a 631 LSSPTIVSAAATSSKSVEIRWKGPEqkkLNGVLTAYRINY-FRLEDS 676
e.....................wneltvpgtttsytltgLkPgteYevrV
++ + ++ + +++ +++++ + ++ vp+++tsy+l++L P++ Ye++V
C09D8.1a 677 KtanlesveydedmddsssfldRMSVVVPSDATSYVLSDLLPYSSYEITV 726
qAvnggG.GpeS<-*
+A + +G GpeS
C09D8.1a 727 AASTMDGyGPES 738
fn3: domain 5 of 9, from 750 to 843: score 62.9, E = 1e-16
*->PsaPtnltvtdvtstsltlsWsppt.gngpitgYevtyRqpkngge.
PsaP+n+ ++ +++ts+ l+W++p ng + gY v + +ge+
C09D8.1a 750 PSAPRNFNAELTSATSVKLTWDAPAaANGALLGYYVYL-DRMVNGEp 795
........wneltvpgtttsytltgLkPgteYevrVqAvnggG.GpeS<-
++++++ + +++++ ++l L P+teY++r+ A n++G+G++S
C09D8.1a 796 vvekgskkRIVMIRDSSKRYFELDSLDPNTEYSFRLNAFNRNGdGEFS 843
*
C09D8.1a - -
[output cut off at A = 10 top alignments]