Motif confirmation by HMMer


hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file:                 /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file:            hmm1/seq/C02C2.1
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Query:  C02C2.1  CE06754   Tyrosinase status:Partially_confirmed SW:P34269 protein_id:AAA27909.2

Scores for sequence family classification (score includes all domains):
Model           Description                             Score    E-value  N
--------        -----------                             -----    ------- ---
ShTK            ShTK domain                              83.5    1.4e-23   2
tyrosinase      Common central domain of tyrosinase      62.6    1.4e-16   2
Arthro_defensin Arthropod defensin                        5.7       0.38   1
DUF333          Domain of unknown function (DUF333)       4.5        6.5   1
DUF281          Domain of unknown function (DUF281)       4.0        5.3   1

Parsed for domains:
Model           Domain  seq-f seq-t    hmm-f hmm-t      score  E-value
--------        ------- ----- -----    ----- -----      -----  -------
tyrosinase        1/2     157   191 ..   102   138 ..    12.8     0.01
DUF333            1/1     323   330 ..    72    79 .]     4.5      6.5
tyrosinase        2/2     289   387 ..   269   379 .]    52.3  9.9e-14
Arthro_defensin   1/1     407   428 ..    14    36 .]     5.7     0.38
ShTK              1/2     479   515 ..     1    44 []    39.8  1.9e-10
DUF281            1/1     518   531 ..     1    14 [.     4.0      5.3
ShTK              2/2     522   558 ..     1    44 []    51.7  5.3e-14

Alignments of top-scoring domains:
tyrosinase: domain 1 of 2, from 157 to 191: score 12.8, E = 0.01
                   *->vHesplFlpWHRwYLyfyEriLgklindptFAlPYWn<-*
                      +H++p Fl WHR Y  + E i  ++i dp  + PYW+
     C02C2.1   157    AHSGPGFLVWHREYMKRME-IALRMI-DPGISMPYWD    191

DUF333: domain 1 of 1, from 323 to 330: score 4.5, E = 6.5
                   *->WElFRsnh<-*
                      WE +R+nh
     C02C2.1   323    WEMWRQNH    330

tyrosinase: domain 2 of 2, from 289 to 387: score 52.3, E = 9.9e-14
                   *->HNpvHiwtGgntkynlPngisngedMgsfysaafDPIFylHHsNVDR
                      H+++H+w+Gg              dM  + ++a+DP+F+lHH++VD
     C02C2.1   289    HASIHLWMGG--------------DMKPPSTSANDPVFFLHHTFVDF 321

                   lWsiWkalggksF....rtdfpeadwlishfrfydenpfppkrvkvrDcf
                   +W+ W   ++++F ++++ +++ a +++s+ + y + + ++k ++ + ++
     C02C2.1   322 IWEMWRQNHQNRFarenQYPPDIAACANSQHFSYAQMRPWDKINRDGLSN 371

                   dtsrpklGYdYedqptpw<-*
                   ++   +  Y Y++ pt
     C02C2.1   372 AYT--DNLYHYAPRPTCN    387

Arthro_defensin: domain 1 of 1, from 407 to 428: score 5.7, E = 0.38
                   *->HClakGGrrGGyCnglkavCvCR<-*
                      HC+ak  + GG C g+ +   C+
     C02C2.1   407    HCVAKV-KPGGLCRGFEGLDSCY    428

ShTK: domain 1 of 2, from 479 to 515: score 39.8, E = 1.9e-10
                   *->tCvDyvDpasdCaawaslGefCnnppYyqdfmkenCpkTCGfCs<-*
                      +C    +++++C +w +++e C++++    +m+++C+k+CG+C+
     C02C2.1   479    NCY---NEDPCCNQWSRQNE-CRTNT---VYMNRYCRKSCGLCQ    515

DUF281: domain 1 of 1, from 518 to 531: score 4.0, E = 5.3
                   *->mtndGCstlavkCe<-*
                      ++n GC  + ++C+
     C02C2.1   518    DNNRGCHDRHISCA    531

ShTK: domain 2 of 2, from 522 to 558: score 51.7, E = 5.3e-14
                   *->tCvDyvDpasdCaawaslGefCnnppYyqdfmkenCpkTCGfCs<-*
                      +C    D++++Ca+w+ +++ C+++    ++m+enC+ TCG C+
     C02C2.1   522    GCH---DRHISCAYWRGQNF-CTRRR---QWMAENCQATCGWCN    558



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