Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/B0240.3
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Query: B0240.3 CE05174 locus:daf-11 guanylate cyclase status:Partially_confirmed TR:Q17462
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
guanylate_cyc Adenylate and Guanylate cyclase catalyt 189.1 6.9e-53 1
pkinase Protein kinase domain 12.7 0.019 2
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
pkinase 1/2 517 558 .. 105 146 .. 3.5 6.8
pkinase 2/2 611 632 .. 177 198 .. 11.2 0.049
guanylate_cyc 1/1 766 959 .. 1 226 [] 189.1 6.9e-53
Alignments of top-scoring domains:
pkinase: domain 1 of 2, from 517 to 558: score 3.5, E = 6.8
*->ialQilrGleYLHsngi.vHRDLKpeNILldendgtvKiaDFG<-*
+ ++il+GleY+H i+ H L N++ld++ vK++ FG
B0240.3 517 FLRDILKGLEYIHASAIdFHGNLTLHNCMLDSH-WIVKLSGFG 558
pkinase: domain 2 of 2, from 611 to 632: score 11.2, E = 0.049
*->rgysskvDvWSlGviLyElltg<-*
+ +++k+D++S+GviL+E+ +
B0240.3 611 PQFGKKCDMYSFGVILHEIILK 632
guanylate_cyc: domain 1 of 1, from 766 to 959: score 189.1, E = 6.9e-53
*->vyaerydeVtilFaDIvgFTalssrhssNngPeevvrlLNelftrFD
v ++ y++ til +DIvgFT+l+s++ P+evv+lL ++ rFD
B0240.3 766 VDPKVYENATILYSDIVGFTSLCSQSQ----PMEVVTLLSGMYQRFD 808
elvdehkfgvyKi......KTiGDaYMaasGlppaakakqtssKlaeeld
++++ g+yK+ ++ +TiGDaY++a+Glp+
B0240.3 809 LIISQQ--GGYKVilnrimETIGDAYCVAAGLPVVM-------------- 842
edsaaHaakladfALamvealqevnvghteggpPlvLyrglqlRiGIHtG
+ +H ++++AL ++ l+ ++++h++g+ l+ R G ++G
B0240.3 843 --EKDHVKSICMIALLQRDCLHHFEIPHRPGTF-------LNCRWGFNSG 883
pVvaGviGgaskrprYdvwGdTVNvASRmEStGvpgekIhVsestyrlLk
pV aGviG +k prY ++G +V +AS+mES Gv +I+++ + +lL+
B0240.3 884 PVFAGVIG--QKAPRYACFGEAVILASKMESSGVED-RIQMTLASQQLLE 930
elesfqfefaleprgevsvkGkgkpGaietYfLkg<-*
e + +qf + ++rg + G g+ i tY+L+g
B0240.3 931 ENF-PQFVC--SNRGGRTIEGIGR---ILTYWLEG 959