Motif confirmation by HMMer
hmmpfam - search a single seq against HMM database
HMMER 2.1.1 (Dec 1998)
Copyright (C) 1992-1998 Washington University School of Medicine
HMMER is freely distributed under the GNU General Public License (GPL).
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HMM file: /home/niguts/usr02/tshini/ykclst/db/Pfam_fs
Sequence file: hmm1/seq/AC7.1
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Query: AC7.1 CE20434 G-protein coupled receptor status:Partially_confirmed TR:Q22876 protein_id:AAB03418.2
Scores for sequence family classification (score includes all domains):
Model Description Score E-value N
-------- ----------- ----- ------- ---
7tm_1 7 transmembrane receptor (rhodopsin family) 166.6 2.3e-53 3
Parsed for domains:
Model Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
7tm_1 1/3 63 138 .. 1 78 [. 60.8 4.3e-19
7tm_1 2/3 156 194 .. 98 137 .. 25.1 1.5e-07
7tm_1 3/3 228 349 .. 143 275 .] 89.6 2.1e-28
Alignments of top-scoring domains:
7tm_1: domain 1 of 3, from 63 to 138: score 60.8, E = 4.3e-19
*->GNlLVilvilrtkklrtptnifilNLAvADLLflltlppwalyylvg
GNlLV+++ l+ + r+ t +filNL +ADL +++ p+ + ++++
AC7.1 63 GNLLVLYITLFRLRVRSITTYFILNLGFADLFTGIFAIPFKFQAALF 109
gsedWpfGsalCklvtaldvvnmyaSillLt<-*
+W +++ lC++v ++ +v++++S+++L+
AC7.1 110 --QEWFLPRSLCRIVPYVETVALTVSVFTLV 138
7tm_1: domain 2 of 3, from 156 to 194: score 25.1, E = 1.5e-07
*->rtsprrAkvvillvWvlalllslPpllfswvktveegngt<-*
++ pr Ak +ll+W++a+l+slP+ lf +++ +++ n+t
AC7.1 156 MS-PRSAKRCVLLIWIMAVLVSLPHGLFHNTYEFPDDNNT 194
7tm_1: domain 3 of 3, from 228 to 349: score 89.6, E = 2.1e-28
*->tvClidfpeestasvstwlvsyvllstlvgFllPllvilvcYtrIlr
++Cl+ +p w+++y++++ ++ +++P++++ ++Yt I+
AC7.1 228 FQCLPVYPDAG------WWKTYNVYLVIIQYFVPMIILDTAYTMIAV 268
tlrkrarkgas.kkrsskerkaaktllvvvvvFvlCWlPyfivllldtlc
++++ ++ ++ + + + +k+++tl++vv F lCW+P+ lll+ l+
AC7.1 269 KIWSLSQSRVElDETKMATQKLMRTLIIVVACFSLCWFPLETYLLLNELK 318
.lsiimsstCelervlptallvtlwLayvNsclNPiIY<-*
++ ++ ++ ++++++wLa++NsclNPiIY
AC7.1 319 pEI-------NGWKYINLVFFFSHWLAMSNSCLNPIIY 349