Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= Y71G12B_13
(2991 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|14916397|gb|AAK73910.1| Hypothetical protein Y71G12B.11b [Cae... 1815 0.0
gi|25143518|ref|NP_490886.2| talin (279.1 kD) (1C213) [Caenorhab... 1763 0.0
gi|39589392|emb|CAE74421.1| Hypothetical protein CBG22153 [Caeno... 1649 0.0
gi|31198901|ref|XP_308398.1| ENSANGP00000019107 [Anopheles gambi... 706 0.0
gi|21355751|ref|NP_648238.1| CG6831-PA [Drosophila melanogaster]... 687 0.0
gi|6739602|gb|AAF27330.1| talin [Homo sapiens] 663 0.0
gi|20521736|dbj|BAA82979.2| KIAA1027 protein [Homo sapiens] 663 0.0
gi|27552808|gb|AAH42923.1| Talin 1 [Homo sapiens] 663 0.0
gi|49022858|dbj|BAC65702.4| mKIAA1027 protein [Mus musculus] 662 0.0
gi|6755809|ref|NP_035732.1| talin [Mus musculus] >gnl|BL_ORD_ID|... 660 0.0
gi|227256|prf||1617167A talin 660 0.0
gi|4235275|gb|AAD13152.1| talin [Homo sapiens] 660 0.0
gi|16753233|ref|NP_006280.2| talin 1 [Homo sapiens] 660 0.0
gi|14916725|sp|Q9Y490|TLN1_HUMAN Talin 1 >gnl|BL_ORD_ID|125746 g... 660 0.0
gi|45383127|ref|NP_989854.1| talin [Gallus gallus] >gnl|BL_ORD_I... 660 0.0
gi|34864297|ref|XP_236367.2| similar to talin 2 [Rattus norvegicus] 658 0.0
gi|22035665|ref|NP_055874.1| talin 2 [Homo sapiens] >gnl|BL_ORD_... 658 0.0
gi|21666571|gb|AAM73764.1| talin 2 [Homo sapiens] 658 0.0
gi|34867875|ref|XP_242982.2| similar to talin [Rattus norvegicus] 655 0.0
gi|33318297|gb|AAQ05019.1| talin 2 [Mus musculus] 630 e-179
gi|47217855|emb|CAG02348.1| unnamed protein product [Tetraodon n... 624 e-177
gi|48097755|ref|XP_391944.1| similar to ENSANGP00000019107 [Apis... 624 e-177
gi|47210482|emb|CAF93389.1| unnamed protein product [Tetraodon n... 454 e-126
gi|10998794|gb|AAG25995.1| talin [Podocoryne carnea] 389 e-106
gi|50752817|ref|XP_413760.1| PREDICTED: similar to talin 2 [Gall... 389 e-106
gi|47225820|emb|CAF98300.1| unnamed protein product [Tetraodon n... 376 e-102
gi|26333597|dbj|BAC30516.1| unnamed protein product [Mus musculus] 324 9e-87
gi|4519179|dbj|BAA75511.1| talin homologue [Dictyostelium discoi... 266 3e-69
gi|41055223|ref|NP_957487.1| similar to talin 2 [Danio rerio] >g... 263 2e-68
gi|50417249|gb|AAH77078.1| Unknown (protein for IMAGE:6901432) [... 260 2e-67
gi|28373663|pdb|1MIX|A Chain A, Crystal Structure Of A Ferm Doma... 238 6e-61
gi|28373665|pdb|1MIZ|B Chain B, Crystal Structure Of An Integrin... 231 6e-59
gi|28373683|pdb|1MK7|B Chain B, Crystal Structure Of An Integrin... 216 3e-54
gi|1362217|pir||A57036 talin - slime mold (Dictyostelium discoid... 205 5e-51
gi|18267199|sp|P54633|TALA_DICDI Filopodin (Talin homolog) >gnl|... 205 5e-51
gi|20520997|dbj|BAA20778.2| KIAA0320 [Homo sapiens] 171 1e-40
gi|50752819|ref|XP_413761.1| PREDICTED: similar to talin 2 [Gall... 152 6e-35
gi|47225819|emb|CAF98299.1| unnamed protein product [Tetraodon n... 148 7e-34
gi|26342541|dbj|BAC34927.1| unnamed protein product [Mus musculus] 142 6e-32
gi|47193899|emb|CAF88570.1| unnamed protein product [Tetraodon n... 79 7e-15
gi|31237908|ref|XP_319689.1| ENSANGP00000021394 [Anopheles gambi... 63 5e-08
gi|48142183|ref|XP_397310.1| similar to ENSANGP00000021394 [Apis... 62 1e-07
gi|16768364|gb|AAL28401.1| GM03112p [Drosophila melanogaster] 59 7e-07
gi|24657225|ref|NP_728936.1| CG14991-PA [Drosophila melanogaster... 59 7e-07
gi|17737417|ref|NP_523571.1| CG7595-PB [Drosophila melanogaster]... 58 1e-06
gi|40882425|gb|AAR96124.1| SD18415p [Drosophila melanogaster] 58 1e-06
gi|27819990|gb|AAL39583.2| LD14917p [Drosophila melanogaster] 58 1e-06
gi|47225818|emb|CAF98298.1| unnamed protein product [Tetraodon n... 57 2e-06
gi|35215302|ref|NP_694515.1| myosin VIIa [Danio rerio] >gnl|BL_O... 57 3e-06
gi|9944237|emb|CAC05419.1| myosin VIIA [Danio rerio] 57 3e-06
gi|21355341|ref|NP_648947.1| CG7729-PA [Drosophila melanogaster]... 57 3e-06
gi|7489245|pir||T07397 kinesin heavy chain-like protein (clone P... 55 8e-06
gi|48128240|ref|XP_396622.1| similar to ENSANGP00000014553 [Apis... 55 1e-05
gi|6678994|ref|NP_032689.1| myosin VIIa; shaker 1 [Mus musculus]... 54 2e-05
gi|4505307|ref|NP_000251.1| myosin VIIA; deafness, autosomal dom... 54 2e-05
gi|23618899|ref|NP_703203.1| myosin VIIA (Usher syndrome 1B (aut... 54 2e-05
gi|8569616|pdb|1EF1|A Chain A, Crystal Structure Of The Moesin F... 53 4e-05
gi|47211881|emb|CAF91177.1| unnamed protein product [Tetraodon n... 53 4e-05
gi|23273527|gb|AAH35882.1| C20orf42 protein [Homo sapiens] 53 5e-05
gi|26392456|sp|Q9BQL6|URP1_HUMAN Unc-112 related protein 1 (Kind... 53 5e-05
gi|26665871|ref|NP_060141.2| chromosome 20 open reading frame 42... 53 5e-05
gi|24899220|dbj|BAC23124.1| KIAA2028 protein [Homo sapiens] 52 6e-05
gi|462608|sp|P26041|MOES_MOUSE Moesin (Membrane-organizing exten... 52 6e-05
gi|4505257|ref|NP_002435.1| moesin [Homo sapiens] >gnl|BL_ORD_ID... 52 6e-05
gi|13540689|ref|NP_110490.1| moesin [Rattus norvegicus] >gnl|BL_... 52 6e-05
gi|45120121|ref|NP_742066.1| similar to PH (pleckstrin homology)... 52 6e-05
gi|14625824|gb|AAK71522.1| moesin/anaplastic lymphoma kinase fus... 52 6e-05
gi|21734037|emb|CAD38637.1| hypothetical protein [Homo sapiens] 52 6e-05
gi|14719519|pdb|1E5W|A Chain A, Structure Of Isolated Ferm Domai... 52 6e-05
gi|6754750|ref|NP_034963.1| moesin [Mus musculus] >gnl|BL_ORD_ID... 52 6e-05
gi|33988037|gb|AAH11827.1| MSN protein [Homo sapiens] >gnl|BL_OR... 52 6e-05
gi|50513540|pdb|1SGH|A Chain A, Moesin Ferm Domain Bound To Ebp5... 52 6e-05
gi|34863387|ref|XP_236234.2| similar to radixin=esp10 product [R... 52 8e-05
gi|7489162|pir||T03792 kinesin-related protein tck1 - common tob... 52 8e-05
gi|26348473|dbj|BAC37876.1| unnamed protein product [Mus musculus] 52 1e-04
gi|17543152|ref|NP_499850.1| protein tyrosine phosphatase non-re... 52 1e-04
gi|34784656|gb|AAH57205.1| Unknown (protein for MGC:68153) [Mus ... 52 1e-04
gi|39587556|emb|CAE58494.1| Hypothetical protein CBG01639 [Caeno... 52 1e-04
gi|6755232|ref|NP_035334.1| protein tyrosine phosphatase, non-re... 52 1e-04
gi|17543160|ref|NP_499856.1| FERM domain (protein 4.1-ezrin-radi... 52 1e-04
gi|45477181|sp|Q64512|PTND_MOUSE Protein tyrosine phosphatase, n... 52 1e-04
gi|26330111|dbj|BAC28794.1| unnamed protein product [Mus musculus] 51 1e-04
gi|47226832|emb|CAG06674.1| unnamed protein product [Tetraodon n... 51 2e-04
gi|39595881|emb|CAE67384.1| Hypothetical protein CBG12867 [Caeno... 51 2e-04
gi|6648536|gb|AAF21215.1| moesin [Xenopus laevis] 51 2e-04
gi|50751909|ref|XP_422573.1| PREDICTED: similar to myosin-VIIb [... 51 2e-04
gi|21750728|dbj|BAC03826.1| unnamed protein product [Homo sapiens] 51 2e-04
gi|50756117|ref|XP_415024.1| PREDICTED: similar to chromosome 20... 51 2e-04
gi|50418501|gb|AAH78311.1| Unknown (protein for IMAGE:7143045) [... 51 2e-04
gi|127236|sp|P26042|MOES_PIG Moesin (Membrane-organizing extensi... 50 2e-04
gi|17505420|ref|NP_491560.1| ezrin, Radixin and Moesin family, E... 50 2e-04
gi|37360889|dbj|BAC98357.1| ERM-1Asv [Caenorhabditis elegans] >g... 50 2e-04
gi|17505422|ref|NP_491559.1| ezrin, Radixin and Moesin family, E... 50 2e-04
gi|47216052|emb|CAG11383.1| unnamed protein product [Tetraodon n... 50 2e-04
gi|47224359|emb|CAG09205.1| unnamed protein product [Tetraodon n... 50 3e-04
gi|18375648|ref|NP_542415.1| protein tyrosine phosphatase, non-r... 50 4e-04
gi|8096551|dbj|BAA96079.2| similar to mouse Ehm2 [Homo sapiens] 50 4e-04
gi|29893547|ref|NP_060894.1| erythrocyte membrane protein band 4... 50 4e-04
gi|18375650|ref|NP_542416.1| protein tyrosine phosphatase, non-r... 50 4e-04
gi|21361812|ref|NP_061987.2| erythrocyte membrane protein band 4... 50 4e-04
gi|31206565|ref|XP_312246.1| ENSANGP00000010755 [Anopheles gambi... 50 4e-04
gi|515031|emb|CAA56563.1| protein-tyrosine-phosphatase [Homo sap... 50 4e-04
gi|5453992|ref|NP_006255.1| protein tyrosine phosphatase, non-re... 50 4e-04
gi|34862031|ref|XP_233830.2| similar to CG12467-PA [Rattus norve... 50 4e-04
gi|18375646|ref|NP_542414.1| protein tyrosine phosphatase, non-r... 50 4e-04
gi|7020445|dbj|BAA91133.1| unnamed protein product [Homo sapiens] 50 4e-04
gi|10130006|gb|AAG13460.1| kinesin-like calmodulin binding prote... 49 5e-04
gi|50731324|ref|XP_417227.1| PREDICTED: similar to Hypothetical ... 49 5e-04
gi|29367597|gb|AAO72660.1| kinesin-like calmodulin-binding prote... 49 5e-04
gi|9506567|ref|NP_062300.1| erythrocyte protein band 4.1-like 4b... 49 5e-04
gi|7435158|pir||S71625 protein-tyrosine-phosphatase (EC 3.1.3.48... 49 5e-04
gi|1232104|dbj|BAA12158.1| protein tyrosine phosphatase [Mus mus... 49 5e-04
gi|1094005|prf||2105234A protein Tyr phosphatase 49 5e-04
gi|33416630|gb|AAH55968.1| Epb4.1l5-prov protein [Xenopus laevis] 49 5e-04
gi|32488670|emb|CAE03597.1| OSJNBa0087O24.20 [Oryza sativa (japo... 49 5e-04
gi|34879408|ref|XP_222561.2| similar to Band 4.1-like protein 5 ... 49 5e-04
gi|47221995|emb|CAG08250.1| unnamed protein product [Tetraodon n... 49 5e-04
gi|10434740|dbj|BAB14360.1| unnamed protein product [Homo sapiens] 49 7e-04
gi|33990951|gb|AAH02626.1| RDX protein [Homo sapiens] 49 7e-04
gi|40254949|ref|NP_065960.2| erythrocyte membrane protein band 4... 49 7e-04
gi|14916925|sp|Q9HCM4|E4L5_HUMAN Band 4.1-like protein 5 49 7e-04
gi|23270923|gb|AAH32822.1| EPB41L5 protein [Homo sapiens] 49 7e-04
gi|91254|pir||A41129 radixin - mouse 49 7e-04
gi|6677699|ref|NP_033067.1| radixin [Mus musculus] >gnl|BL_ORD_I... 49 7e-04
gi|28436809|gb|AAH47109.1| Radixin [Homo sapiens] 49 7e-04
gi|4506467|ref|NP_002897.1| radixin [Homo sapiens] >gnl|BL_ORD_I... 49 7e-04
gi|32363498|sp|P26043|RADI_MOUSE Radixin (ESP10) >gnl|BL_ORD_ID|... 49 7e-04
gi|26353266|dbj|BAC40263.1| unnamed protein product [Mus musculus] 49 7e-04
gi|29726310|pdb|1J19|A Chain A, Crystal Structure Of The Radxin ... 49 7e-04
gi|31544939|gb|AAH53417.1| Unknown (protein for MGC:58329) [Mus ... 49 7e-04
gi|10835742|pdb|1GC6|A Chain A, Crystal Structure Of The Radixin... 49 7e-04
gi|28071088|emb|CAD61925.1| unnamed protein product [Homo sapiens] 49 7e-04
gi|2135746|pir||S69890 mitogen inducible gene mig-2 - human >gnl... 49 7e-04
gi|31248110|ref|XP_320993.1| ENSANGP00000019858 [Anopheles gambi... 49 7e-04
gi|29789006|ref|NP_006823.1| pleckstrin homology domain containi... 49 7e-04
gi|8979743|emb|CAB96753.1| Band4.1-like5 protein [Canis familiaris] 49 0.001
gi|34877320|ref|XP_344633.1| similar to Hypothetical protein KIA... 49 0.001
gi|50510981|dbj|BAD32476.1| mKIAA1548 protein [Mus musculus] 49 0.001
gi|13278193|gb|AAH03937.1| Epb4.1l5 protein [Mus musculus] >gnl|... 49 0.001
gi|30841014|ref|NP_663481.2| erythrocyte protein band 4.1-like 5... 49 0.001
gi|627585|pir||A54971 protein-tyrosine-phosphatase (EC 3.1.3.48)... 49 0.001
gi|30983603|gb|AAP41107.1| kinesin-like calmodulin binding prote... 49 0.001
gi|27769222|gb|AAH42247.1| MGC53981 protein [Xenopus laevis] 49 0.001
gi|26341510|dbj|BAC34417.1| unnamed protein product [Mus musculus] 48 0.001
gi|50400507|sp|Q8BIE6|FRM4_MOUSE FERM domain containing protein ... 48 0.001
gi|40254210|ref|NP_766063.2| RIKEN 2700017I06 [Mus musculus] >gn... 48 0.001
gi|15599829|ref|NP_253323.1| probable chemotaxis transducer [Pse... 48 0.001
gi|50745593|ref|XP_420170.1| PREDICTED: similar to Moesin (Membr... 48 0.001
gi|131821|sp|P26044|RADI_PIG Radixin (Moesin B) >gnl|BL_ORD_ID|5... 48 0.001
gi|50748962|ref|XP_421477.1| PREDICTED: similar to pleckstrin ho... 48 0.001
gi|41019537|sp|P59113|URP1_MOUSE Unc-112 related protein 1 (Kind... 48 0.001
gi|38258078|sp|Q8CIB5|PKC1_MOUSE Pleckstrin homology domain cont... 48 0.001
gi|21223757|ref|NP_629536.1| large Ala/Glu-rich protein [Strepto... 48 0.002
gi|33469135|ref|NP_060497.2| FERM domain containing 4A [Homo sap... 48 0.002
gi|32039917|ref|ZP_00138189.1| COG0840: Methyl-accepting chemota... 48 0.002
gi|14348876|gb|AAK61353.1| ezrin/radixin/moesin [Biomphalaria gl... 48 0.002
gi|7242943|dbj|BAA92532.1| KIAA1294 protein [Homo sapiens] 48 0.002
gi|47221712|emb|CAG10184.1| unnamed protein product [Tetraodon n... 48 0.002
gi|45382077|ref|NP_990082.1| radixin [Gallus gallus] >gnl|BL_ORD... 48 0.002
gi|17505679|ref|NP_491587.1| FERM domain (protein 4.1-ezrin-radi... 48 0.002
gi|50403803|sp|Q9P2Q2|FRM4_HUMAN FERM domain containing protein 4 48 0.002
gi|34858776|ref|XP_215844.2| similar to chromosome 20 open readi... 47 0.002
gi|27807067|ref|NP_777015.1| protein tyrosine phosphatase, non-r... 47 0.002
gi|50750658|ref|XP_422083.1| PREDICTED: similar to Band4.1-like5... 47 0.002
gi|29436484|gb|AAH49479.1| Msn protein [Danio rerio] 47 0.002
gi|30698168|ref|NP_851276.1| kinesin-like calmodulin-binding pro... 47 0.002
gi|30698170|ref|NP_569022.2| kinesin-like calmodulin-binding pro... 47 0.002
gi|49903353|gb|AAH76691.1| Unknown (protein for IMAGE:6982511) [... 47 0.002
gi|50418251|gb|AAH77819.1| Unknown (protein for MGC:80470) [Xeno... 47 0.002
gi|20072914|gb|AAH26416.1| Myo7b protein [Mus musculus] 47 0.003
gi|17505677|ref|NP_491586.1| FERM domain (protein 4.1-ezrin-radi... 47 0.003
gi|17564928|ref|NP_506628.1| pleckstrin-like, UNCoordinated loco... 47 0.003
gi|48096008|ref|XP_392377.1| similar to ENSANGP00000006015 [Apis... 47 0.003
gi|39589851|emb|CAE60849.1| Hypothetical protein CBG04558 [Caeno... 47 0.003
gi|7022113|dbj|BAA91492.1| unnamed protein product [Homo sapiens] 47 0.003
gi|45382429|ref|NP_990216.1| ezrin [Gallus gallus] >gnl|BL_ORD_I... 47 0.004
gi|47717352|gb|AAR97566.1| frizzled-8 associated multidomain pro... 47 0.004
gi|50746555|ref|XP_420550.1| PREDICTED: similar to protein tyros... 47 0.004
gi|14161694|ref|NP_115770.1| myosin VIIb [Mus musculus] >gnl|BL_... 47 0.004
gi|20151933|gb|AAM11326.1| GH01330p [Drosophila melanogaster] 46 0.005
gi|32450442|gb|AAH54026.1| Moe protein [Danio rerio] 46 0.005
gi|2586157|gb|AAC49901.1| kinesin-like calmodulin-binding protei... 46 0.005
gi|47207135|emb|CAF90714.1| unnamed protein product [Tetraodon n... 46 0.005
gi|1237102|gb|AAC37475.1| calmodulin-binding protein >gnl|BL_ORD... 46 0.006
gi|39997746|ref|NP_953697.1| methyl-accepting chemotaxis protein... 46 0.006
gi|29829400|ref|NP_824034.1| putative M protein [Streptomyces av... 46 0.006
gi|32189724|ref|NP_859454.1| hypothetical protein Chr3_0210 [Lei... 46 0.006
gi|48095943|ref|XP_392367.1| similar to ENSANGP00000019858 [Apis... 46 0.006
gi|14195008|sp|Q9JI55|PLE1_CRIGR Plectin 1 (PLTN) (PCN) (300-kDa... 45 0.008
gi|17647629|ref|NP_523413.1| CG14228-PA [Drosophila melanogaster... 45 0.008
gi|49068184|ref|XP_398381.1| hypothetical protein UM00766.1 [Ust... 45 0.008
gi|29243976|ref|NP_808274.1| expressed sequence AI256725 [Mus mu... 45 0.008
gi|50511259|dbj|BAD32615.1| mKIAA2028 protein [Mus musculus] 45 0.008
gi|47229266|emb|CAG04018.1| unnamed protein product [Tetraodon n... 45 0.010
gi|47226236|emb|CAG08383.1| unnamed protein product [Tetraodon n... 45 0.010
gi|37360188|dbj|BAC98072.1| mKIAA1013 protein [Mus musculus] 45 0.010
gi|48136060|ref|XP_393357.1| similar to ENSANGP00000010755 [Apis... 45 0.010
gi|17380674|gb|AAL36167.1| putative kinesin calmodulin-binding p... 45 0.010
gi|16588846|gb|AAL26916.1| GRP1 binding protein GRSP1 [Mus muscu... 45 0.010
gi|16588849|gb|AAL26917.1| GRP1 binding protein GRSP1 [Mus muscu... 45 0.010
gi|21553103|ref|NP_660130.1| GRP1-binding protein GRSP1; Golgi-a... 45 0.010
gi|21283053|ref|NP_646141.1| ORFID:MW1324~hypothetical protein, ... 45 0.013
gi|34861537|ref|XP_219540.2| similar to cDNA sequence BC032204 [... 45 0.013
gi|47225817|emb|CAF98297.1| unnamed protein product [Tetraodon n... 45 0.013
gi|48857657|ref|ZP_00311646.1| COG0840: Methyl-accepting chemota... 45 0.013
gi|41053841|ref|NP_957198.1| hypothetical protein MGC64101 [Dani... 45 0.013
gi|24418903|ref|NP_722490.1| cDNA sequence BC032204 [Mus musculu... 45 0.013
gi|37590285|gb|AAH59329.1| MGC69069 protein [Xenopus laevis] 45 0.013
gi|15292569|gb|AAK93553.1| SD07967p [Drosophila melanogaster] 44 0.018
gi|47227379|emb|CAF96928.1| unnamed protein product [Tetraodon n... 44 0.018
gi|47219895|emb|CAF97165.1| unnamed protein product [Tetraodon n... 44 0.018
gi|42733836|gb|AAS38754.1| hypothetical protein [Dictyostelium d... 44 0.018
gi|41281905|ref|NP_848537.1| UNC-112 related protein 2 long form... 44 0.018
gi|34869626|ref|XP_214148.2| similar to mitogen inducible gene m... 44 0.018
gi|28626504|ref|NP_113659.3| UNC-112 related protein 2 short for... 44 0.018
gi|21752646|dbj|BAC04220.1| unnamed protein product [Homo sapiens] 44 0.018
gi|31203141|ref|XP_310519.1| ENSANGP00000023320 [Anopheles gambi... 44 0.023
gi|49523130|gb|AAH75273.1| Unknown (protein for MGC:88900) [Xeno... 44 0.023
gi|49483625|ref|YP_040849.1| very large surface anchored protein... 44 0.023
gi|13540714|ref|NP_071796.1| plectin [Rattus norvegicus] >gnl|BL... 44 0.030
gi|40849906|gb|AAR95665.1| plectin 11 [Rattus norvegicus] 44 0.030
gi|40849900|gb|AAR95662.1| plectin 8 [Rattus norvegicus] 44 0.030
gi|40849886|gb|AAR95655.1| plectin 1 [Rattus norvegicus] 44 0.030
gi|40849888|gb|AAR95656.1| plectin 2 [Rattus norvegicus] 44 0.030
gi|40849892|gb|AAR95658.1| plectin 4 [Rattus norvegicus] >gnl|BL... 44 0.030
gi|40849896|gb|AAR95660.1| plectin 6 [Rattus norvegicus] 44 0.030
gi|40849890|gb|AAR95657.1| plectin 3 [Rattus norvegicus] 44 0.030
gi|47223930|emb|CAG06107.1| unnamed protein product [Tetraodon n... 44 0.030
gi|40849904|gb|AAR95664.1| plectin 10 [Rattus norvegicus] 44 0.030
gi|40849898|gb|AAR95661.1| plectin 7 [Rattus norvegicus] 44 0.030
gi|32363162|sp|Q8HZQ5|EZRI_RABIT Ezrin (p81) (Cytovillin) (Villi... 43 0.039
gi|37549668|ref|XP_114303.2| GRP1-binding protein GRSP1 [Homo sa... 43 0.039
gi|14916855|sp|Q9Y2L6|YA13_HUMAN Hypothetical protein KIAA1013 >... 43 0.039
gi|34866136|ref|XP_234332.2| similar to mKIAA1200 protein [Rattu... 43 0.051
gi|7549210|gb|AAF63787.1| 200 kDa antigen p200 [Babesia bigemina] 43 0.051
gi|41056121|ref|NP_956383.1| erythrocyte membrane protein band 4... 43 0.051
gi|46849979|gb|AAT02412.1| mosaic eyes [Danio rerio] 43 0.051
gi|24582545|ref|NP_723294.1| CG6976-PB [Drosophila melanogaster]... 42 0.067
gi|7513061|pir||T00363 hypothetical protein KIAA0674 - human (fr... 42 0.067
gi|46366086|ref|ZP_00228489.1| COG3599: Cell division initiation... 42 0.067
gi|42659249|ref|XP_376903.1| KIAA0674 protein [Homo sapiens] 42 0.067
gi|11359838|pir||A59233 myosin VII-like protein - fruit fly (Dro... 42 0.067
gi|24582549|ref|NP_652630.2| CG6976-PA [Drosophila melanogaster]... 42 0.067
gi|15790077|ref|NP_279901.1| Htr15 transducer; Htr15 [Halobacter... 42 0.067
gi|9229886|dbj|BAB00616.1| ezrin/radixin/moesin (ERM)-like prote... 42 0.067
gi|48101428|ref|XP_392673.1| similar to schwannomin [Apis mellif... 42 0.087
gi|47228015|emb|CAF97644.1| unnamed protein product [Tetraodon n... 42 0.087
gi|30584405|gb|AAP36455.1| Homo sapiens myosin regulatory light ... 42 0.087
gi|34876034|ref|XP_213997.2| similar to protein Tyr phosphatase ... 42 0.087
gi|38788243|ref|NP_037394.2| myosin regulatory light chain inter... 42 0.087
gi|10834718|gb|AAG23789.1| PP5242 [Homo sapiens] >gnl|BL_ORD_ID|... 42 0.087
gi|22122535|ref|NP_666166.1| pleckstrin homology domain containi... 42 0.11
gi|25395273|pir||F87775 protein C24A11.8 [imported] - Caenorhabd... 42 0.11
gi|47222611|emb|CAG02976.1| unnamed protein product [Tetraodon n... 42 0.11
gi|44890398|gb|AAH66803.1| BC032204 protein [Mus musculus] 42 0.11
gi|41471985|gb|AAS07420.1| unknown [Homo sapiens] 41 0.15
gi|13431606|sp|O00522|KRT1_HUMAN Krev interaction trapped 1 (Kri... 41 0.15
gi|6678571|ref|NP_033536.1| villin 2 [Mus musculus] >gnl|BL_ORD_... 41 0.15
gi|32363497|sp|P26040|EZRI_MOUSE Ezrin (p81) (Cytovillin) (Villi... 41 0.15
gi|12832989|dbj|BAB22341.1| unnamed protein product [Mus musculus] 41 0.15
gi|23510054|ref|NP_702720.1| hypothetical protein [Plasmodium fa... 41 0.15
gi|29165636|ref|NP_049403.2| putative tail component protein [St... 41 0.15
gi|46365836|ref|ZP_00228265.1| COG1196: Chromosome segregation A... 41 0.15
gi|50733631|ref|XP_418932.1| PREDICTED: similar to PP5242 [Gallu... 41 0.15
gi|6601394|gb|AAF18974.1| myosin regulatory light chain interact... 41 0.15
gi|12044278|gb|AAG47774.1| krev interaction trapped 1 [Homo sapi... 41 0.15
gi|31581522|ref|NP_004903.2| krev interaction trapped 1; ankyrin... 41 0.15
gi|37577187|gb|AAQ94072.1| Krev interaction trapped 1 variant [H... 41 0.15
gi|17553794|ref|NP_498303.1| FERM domain (protein 4.1-ezrin-radi... 41 0.15
gi|47564094|ref|NP_001001166.1| krit1 protein [Bos taurus] >gnl|... 41 0.15
gi|49114816|gb|AAH72760.1| Unknown (protein for IMAGE:5073172) [... 41 0.19
gi|21614499|ref|NP_003370.2| villin 2; ezrin; cytovillin [Homo s... 41 0.19
gi|46249758|gb|AAH68458.1| Villin 2 [Homo sapiens] 41 0.19
gi|119717|sp|P15311|EZRI_HUMAN Ezrin (p81) (Cytovillin) (Villin ... 41 0.19
gi|11276938|pir||T47177 hypothetical protein DKFZp762H157.1 - hu... 41 0.19
gi|26333997|dbj|BAC30716.1| unnamed protein product [Mus musculus] 41 0.19
gi|340217|gb|AAA61278.1| cytovillin 2 41 0.19
gi|18312645|ref|NP_559312.1| hypothetical protein PAE1451 [Pyrob... 41 0.19
gi|16307334|gb|AAH10206.1| Myosin regulatory light chain interac... 41 0.19
gi|28948869|pdb|1NI2|A Chain A, Structure Of The Active Ferm Dom... 41 0.19
gi|30841031|ref|NP_722484.2| myosin regulatory light chain inter... 41 0.19
gi|31199365|ref|XP_308630.1| ENSANGP00000007560 [Anopheles gambi... 40 0.25
gi|41724186|ref|ZP_00151052.1| COG0810: Periplasmic protein TonB... 40 0.25
gi|6330407|dbj|BAA86514.1| KIAA1200 protein [Homo sapiens] 40 0.25
gi|32564748|ref|NP_494788.2| putative cytoplasmic protein, with ... 40 0.25
gi|48848267|ref|ZP_00302513.1| COG1530: Ribonucleases G and E [N... 40 0.25
gi|34874052|ref|XP_225220.2| similar to myosin regulatory light ... 40 0.25
gi|27806351|ref|NP_776642.1| villin 2; ezrin [Bos taurus] >gnl|B... 40 0.25
gi|42660304|ref|XP_375087.1| pleckstrin homology domain containi... 40 0.25
gi|41018567|gb|AAR98175.1| ORF080 virion core protein [Orf virus] 39 0.27
gi|28521592|ref|XP_126961.3| RIKEN cDNA D630024D12 gene [Mus mus... 40 0.33
gi|28972660|dbj|BAC65746.1| mKIAA1200 protein [Mus musculus] 40 0.33
gi|18858631|ref|NP_571298.1| erythrocyte protein band 4.1-like 4... 40 0.33
gi|38174278|gb|AAH60893.1| Epb4.1l4 protein [Danio rerio] 40 0.33
gi|48831929|ref|ZP_00288976.1| COG0840: Methyl-accepting chemota... 40 0.33
gi|47229971|emb|CAG10385.1| unnamed protein product [Tetraodon n... 40 0.33
gi|1709073|sp|P52962|MOES_LYTVA Moesin >gnl|BL_ORD_ID|1052388 gi... 40 0.33
gi|39998367|ref|NP_954318.1| hypothetical protein GSU3278 [Geoba... 40 0.43
gi|7507086|pir||T25859 hypothetical protein T04C9.6 - Caenorhabd... 40 0.43
gi|22024255|ref|NP_611787.2| CG3493-PA [Drosophila melanogaster]... 40 0.43
gi|18447644|gb|AAL68382.1| SD05887p [Drosophila melanogaster] 40 0.43
gi|9634660|ref|NP_038334.1| ORF33 [Streptococcus thermophilus ba... 40 0.43
gi|47198317|emb|CAF88083.1| unnamed protein product [Tetraodon n... 40 0.43
gi|47223921|emb|CAG06098.1| unnamed protein product [Tetraodon n... 40 0.43
gi|39589692|emb|CAE66927.1| Hypothetical protein CBG12316 [Caeno... 40 0.43
gi|39582082|emb|CAE63725.1| Hypothetical protein CBG08250 [Caeno... 39 0.57
gi|17902245|gb|AAL47844.1| EZRIN [Rattus norvegicus] 39 0.57
gi|48858617|ref|ZP_00312567.1| COG0840: Methyl-accepting chemota... 39 0.57
gi|10505380|gb|AAG18456.1| KRIT1 [Mus musculus] 39 0.57
gi|38565534|gb|AAR24089.1| krev interaction trapped-1A [Mus musc... 39 0.57
gi|47204860|emb|CAF96115.1| unnamed protein product [Tetraodon n... 39 0.74
gi|31239145|ref|XP_319986.1| ENSANGP00000005315 [Anopheles gambi... 39 0.74
gi|26327089|dbj|BAC27288.1| unnamed protein product [Mus musculus] 39 0.74
gi|47228933|emb|CAG09448.1| unnamed protein product [Tetraodon n... 39 0.74
gi|39590564|emb|CAE64934.1| Hypothetical protein CBG09764 [Caeno... 39 0.74
gi|23473946|ref|ZP_00129241.1| COG0840: Methyl-accepting chemota... 39 0.74
gi|47219438|emb|CAG10802.1| unnamed protein product [Tetraodon n... 39 0.97
gi|482955|pir||B32491 myosin heavy chain 2, muscle - fruit fly (... 39 0.97
gi|48735073|gb|AAH72328.1| Unknown (protein for MGC:83142) [Xeno... 39 0.97
gi|482280|pir||A32491 myosin heavy chain 1, muscle - fruit fly (... 39 0.97
gi|34859473|ref|XP_218972.2| nuclear mitotic apparatus protein 1... 39 0.97
gi|28829087|gb|AAO51651.1| similar to Dictyostelium discoideum (... 39 0.97
gi|8843977|gb|AAF80198.1| Cag-Y [Helicobacter pylori] 39 0.97
gi|1351383|sp|P22865|US45_LACLC Secreted 45 kDa protein precurso... 39 0.97
gi|21233389|ref|NP_639306.1| TonB-like protein [Xanthomonas camp... 39 0.97
gi|48846637|ref|ZP_00300897.1| COG0840: Methyl-accepting chemota... 39 0.97
gi|40789071|dbj|BAA06542.2| KIAA0064 [Homo sapiens] 38 1.3
gi|46366850|ref|ZP_00229032.1| COG0419: ATPase involved in DNA r... 38 1.3
gi|7661890|ref|NP_055563.1| sorting nexin 17 [Homo sapiens] >gnl... 38 1.3
gi|39584919|emb|CAE64343.1| Hypothetical protein CBG09029 [Caeno... 38 1.3
gi|15924425|ref|NP_371959.1| hypothetical protein SAV1435 [Staph... 38 1.3
gi|28175281|gb|AAH45228.1| Snx17-prov protein [Xenopus laevis] 38 1.3
gi|34868524|ref|XP_345536.1| similar to Protein tyrosine phospha... 38 1.3
gi|39995862|ref|NP_951813.1| methyl-accepting chemotaxis protein... 38 1.3
gi|13994219|ref|NP_109600.1| cerebral cavernous malformations 1 ... 38 1.3
gi|30583777|gb|AAP36137.1| Homo sapiens sorting nexin 17 [synthe... 38 1.3
gi|13543795|gb|AAH06045.1| Plekhh1 protein [Mus musculus] 38 1.6
gi|21220850|ref|NP_626629.1| putative secreted protein [Streptom... 38 1.6
gi|4249701|gb|AAD13772.1| myosin heavy chain [Rana catesbeiana] 38 1.6
gi|34869451|ref|XP_233129.2| similar to hypothetical protein FLJ... 38 1.6
gi|48769508|ref|ZP_00273853.1| COG0532: Translation initiation f... 38 1.6
gi|22137360|gb|AAH28900.1| Plekhh1 protein [Mus musculus] 38 1.6
gi|30064871|ref|NP_839042.1| putative alpha helix chain [Shigell... 38 1.6
gi|15235483|ref|NP_193013.1| auxilin-related [Arabidopsis thalia... 38 1.6
gi|34915026|ref|NP_918860.1| P0458A05.18 [Oryza sativa (japonica... 38 1.6
gi|26250600|ref|NP_756640.1| DNA recombination protein rmuC [Esc... 38 1.6
gi|15804424|ref|NP_290464.1| putative alpha helix chain [Escheri... 38 1.6
gi|148230|gb|AAA67627.1| o475 38 1.6
gi|50758979|ref|XP_417502.1| PREDICTED: similar to Docking prote... 38 1.6
gi|26006145|dbj|BAC41415.1| mKIAA0320 protein [Mus musculus] 37 2.1
gi|34880493|ref|XP_213902.2| similar to laminin gamma 2 chain pr... 37 2.1
gi|15487212|emb|CAC37150.2| hypothetical predicted protein P1046... 37 2.1
gi|37538193|gb|AAQ92980.1| KRIT1B [Mus musculus] 37 2.1
gi|32474271|ref|NP_867265.1| probable IgA-specific metalloendope... 37 2.1
gi|34854305|ref|XP_342635.1| similar to krev interaction trapped... 37 2.1
gi|31217814|ref|XP_316511.1| ENSANGP00000013488 [Anopheles gambi... 37 2.1
gi|26334581|dbj|BAC30991.1| unnamed protein product [Mus musculus] 37 2.1
gi|50254628|gb|EAL17376.1| hypothetical protein CNBN0060 [Crypto... 37 2.8
gi|48832090|ref|ZP_00289133.1| COG0840: Methyl-accepting chemota... 37 2.8
gi|49079844|ref|XP_403522.1| hypothetical protein UM05907.1 [Ust... 37 2.8
gi|47498024|ref|NP_998873.1| hypothetical protein MGC69341 [Xeno... 37 2.8
gi|46364565|ref|ZP_00227167.1| COG0840: Methyl-accepting chemota... 37 2.8
gi|48109856|ref|XP_396252.1| similar to CG10701-PD [Apis mellifera] 37 2.8
gi|12643676|sp|P76072|STFR_ECOLI Side tail fiber protein homolog... 37 2.8
gi|47219137|emb|CAG01800.1| unnamed protein product [Tetraodon n... 37 2.8
gi|23016517|ref|ZP_00056272.1| COG0840: Methyl-accepting chemota... 37 2.8
gi|16129333|ref|NP_415890.1| side tail fiber protein homolog fro... 37 2.8
gi|47228169|emb|CAF97798.1| unnamed protein product [Tetraodon n... 37 3.7
gi|15674211|ref|NP_268386.1| hypothetical protein L96658 [Lactoc... 37 3.7
gi|31235885|ref|XP_319316.1| ENSANGP00000023510 [Anopheles gambi... 37 3.7
gi|88200|pir||A23767 myosin heavy chain, fast skeletal muscle - ... 37 3.7
gi|50732471|ref|XP_418651.1| PREDICTED: similar to krev interact... 37 3.7
gi|50749468|ref|XP_421649.1| PREDICTED: similar to FERM and PDZ ... 37 3.7
gi|97960|pir||JN0097 secreted 45K protein precursor - Lactococcu... 37 3.7
gi|42523931|ref|NP_969311.1| MCP methyl chemotaxis protein [Bdel... 36 4.8
gi|20455497|sp|P05661|MYSA_DROME Myosin heavy chain, muscle 36 4.8
gi|157891|gb|AAA28686.1| myosin heavy chain 36 4.8
gi|24584710|ref|NP_724007.1| CG17927-PB [Drosophila melanogaster... 36 4.8
gi|47204348|emb|CAF90769.1| unnamed protein product [Tetraodon n... 36 4.8
gi|47208044|emb|CAF92932.1| unnamed protein product [Tetraodon n... 36 4.8
gi|103256|pir||A35815 myosin heavy chain 1, muscle - fruit fly (... 36 4.8
gi|26346711|dbj|BAC37004.1| unnamed protein product [Mus musculus] 36 4.8
gi|45527406|ref|ZP_00178606.1| COG0840: Methyl-accepting chemota... 36 4.8
gi|24211031|ref|NP_710147.1| sorting nexin 17 [Mus musculus] >gn... 36 4.8
gi|46199918|ref|YP_005585.1| phage shock protein A [Thermus ther... 36 4.8
gi|24584714|ref|NP_724009.1| CG17927-PL [Drosophila melanogaster... 36 4.8
gi|21355155|ref|NP_651209.1| CG5429-PA [Drosophila melanogaster]... 36 4.8
gi|24584716|ref|NP_724010.1| CG17927-PM [Drosophila melanogaster... 36 4.8
gi|24584712|ref|NP_724008.1| CG17927-PK [Drosophila melanogaster... 36 4.8
gi|50734574|ref|XP_419000.1| PREDICTED: similar to myosin X [Gal... 36 4.8
gi|12855414|dbj|BAB30329.1| unnamed protein product [Mus musculus] 36 4.8
gi|103259|pir||C35815 myosin heavy chain 3, muscle - fruit fly (... 36 4.8
gi|9366705|emb|CAB95467.1| DNAJ-like protein, possible [Trypanos... 36 4.8
gi|50750571|ref|XP_426587.1| PREDICTED: similar to myosin X [Gal... 36 4.8
gi|48836108|ref|ZP_00293105.1| COG2268: Uncharacterized protein ... 36 4.8
gi|50753294|ref|XP_413944.1| PREDICTED: similar to FERM domain c... 36 4.8
gi|28972399|dbj|BAC65653.1| mKIAA0799 protein [Mus musculus] 36 6.3
gi|19354084|gb|AAH24692.1| Myo10 protein [Mus musculus] 36 6.3
gi|46091559|dbj|BAD13998.1| cag pathogenicity island protein [He... 36 6.3
gi|50428778|gb|AAT77099.1| myosin 10 [Xenopus laevis] 36 6.3
gi|24581873|ref|NP_524924.2| CG18251-PB [Drosophila melanogaster... 36 6.3
gi|39594956|emb|CAE70824.1| Hypothetical protein CBG17595 [Caeno... 36 6.3
gi|24640670|ref|NP_525082.2| CG10701-PD [Drosophila melanogaster... 36 6.3
gi|11362271|pir||T47237 myosin II heavy chain [imported] - Naegl... 36 6.3
gi|49085444|ref|XP_404843.1| hypothetical protein AN0706.2 [Aspe... 36 6.3
gi|45554605|ref|NP_996387.1| CG10701-PJ [Drosophila melanogaster... 36 6.3
gi|45552221|ref|NP_995633.1| CG18251-PC [Drosophila melanogaster... 36 6.3
gi|31414576|dbj|BAC77268.1| UsoAp [Emericella nidulans] 36 6.3
gi|34855017|ref|XP_226874.2| similar to myosin X [Rattus norvegi... 36 6.3
gi|31208097|ref|XP_313015.1| ENSANGP00000011297 [Anopheles gambi... 36 6.3
gi|34868447|ref|XP_342847.1| similar to mKIAA0674 protein [Rattu... 35 8.2
gi|7503548|pir||T22298 hypothetical protein F46C3.3 - Caenorhabd... 35 8.2
gi|49078010|ref|XP_402801.1| hypothetical protein UM05186.1 [Ust... 35 8.2
gi|20810395|gb|AAH29093.1| 5830467P10Rik protein [Mus musculus] 35 8.2
gi|25149984|ref|NP_509914.2| heavy chain, Unconventional Myosin ... 35 8.2
gi|47228857|emb|CAG09372.1| unnamed protein product [Tetraodon n... 35 8.2
gi|454796|gb|AAA50581.1| antigen II/3 35 8.2
gi|38258879|sp|P56674|HH_DROHY Hedgehog protein precursor 35 8.2
gi|45682710|ref|ZP_00194145.1| COG1196: Chromosome segregation A... 35 8.2
gi|21234196|ref|NP_639800.1| hypothetical protein [Streptomyces ... 35 8.2
gi|999397|gb|AAB34104.1| hedgehog hh protein homolog [Drosophila... 35 8.2
gi|9506909|ref|NP_062345.1| myosin X; myosin-X [Mus musculus] >g... 35 8.2
gi|23102768|ref|ZP_00089267.1| COG0810: Periplasmic protein TonB... 35 8.2
gi|32404446|ref|XP_322836.1| hypothetical protein [Neurospora cr... 35 8.2
>gi|14916397|gb|AAK73910.1| Hypothetical protein Y71G12B.11b
[Caenorhabditis elegans]
Length = 996
Score = 1815 bits (4702), Expect = 0.0
Identities = 928/996 (93%), Positives = 928/996 (93%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS 180
MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS
Sbjct: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS 60
Query: 181 LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI 360
LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI
Sbjct: 61 LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI 120
Query: 361 GISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMRK 540
GISNYEEYSLVRDDILM STWNL IYGTMRK
Sbjct: 121 GISNYEEYSLVRDDILMQNGGGGGGGGGQNGGSTWNLKEKESRSKSSDRGGGGIYGTMRK 180
Query: 541 KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL 720
KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL
Sbjct: 181 KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL 240
Query: 721 NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEYXXX 900
NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEY
Sbjct: 241 NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEYAKN 300
Query: 901 XXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV 1080
MYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV
Sbjct: 301 KENEKKVVAMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV 360
Query: 1081 NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI 1260
NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI
Sbjct: 361 NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI 420
Query: 1261 QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG 1440
QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG
Sbjct: 421 QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG 480
Query: 1441 VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV 1620
VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV
Sbjct: 481 VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV 540
Query: 1621 EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXXXXXXXXXXE 1800
EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMG E
Sbjct: 541 EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGAATAQVVQWTAVE 600
Query: 1801 EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE 1980
EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE
Sbjct: 601 EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE 660
Query: 1981 TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT 2160
TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT
Sbjct: 661 TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT 720
Query: 2161 ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN 2340
ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN
Sbjct: 721 ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN 780
Query: 2341 NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR 2520
NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR
Sbjct: 781 NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR 840
Query: 2521 TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM 2700
TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM
Sbjct: 841 TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM 900
Query: 2701 ILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAKQTAYDATQ 2880
ILATEQAESQPRQVETEYALRTAAERLG HIMQRLEQAAKQTAYDATQ
Sbjct: 901 ILATEQAESQPRQVETEYALRTAAERLGQVTNETTQEQQEQHIMQRLEQAAKQTAYDATQ 960
Query: 2881 TISAANSAKKKQQEHKRTETTEQLLVDDSHTILRIR 2988
TISAANSAKKKQQEHKRTETTEQLLVDDSHTILRIR
Sbjct: 961 TISAANSAKKKQQEHKRTETTEQLLVDDSHTILRIR 996
>gi|25143518|ref|NP_490886.2| talin (279.1 kD) (1C213) [Caenorhabditis
elegans]
gi|954750|gb|AAA74747.1| talin
gi|16604230|gb|AAK73909.2| Hypothetical protein Y71G12B.11a
[Caenorhabditis elegans]
Length = 2553
Score = 1763 bits (4566), Expect = 0.0
Identities = 901/969 (92%), Positives = 901/969 (92%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS 180
MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS
Sbjct: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS 60
Query: 181 LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI 360
LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI
Sbjct: 61 LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI 120
Query: 361 GISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMRK 540
GISNYEEYSLVRDDILM STWNL IYGTMRK
Sbjct: 121 GISNYEEYSLVRDDILMQNGGGGGGGGGQNGGSTWNLKEKESRSKSSDRGGGGIYGTMRK 180
Query: 541 KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL 720
KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL
Sbjct: 181 KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL 240
Query: 721 NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEYXXX 900
NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEY
Sbjct: 241 NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEYAKN 300
Query: 901 XXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV 1080
MYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV
Sbjct: 301 KENEKKVVAMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV 360
Query: 1081 NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI 1260
NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI
Sbjct: 361 NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI 420
Query: 1261 QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG 1440
QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG
Sbjct: 421 QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG 480
Query: 1441 VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV 1620
VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV
Sbjct: 481 VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV 540
Query: 1621 EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXXXXXXXXXXE 1800
EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMG E
Sbjct: 541 EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGAATAQVVQWTAVE 600
Query: 1801 EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE 1980
EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE
Sbjct: 601 EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE 660
Query: 1981 TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT 2160
TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT
Sbjct: 661 TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT 720
Query: 2161 ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN 2340
ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN
Sbjct: 721 ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN 780
Query: 2341 NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR 2520
NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR
Sbjct: 781 NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR 840
Query: 2521 TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM 2700
TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM
Sbjct: 841 TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM 900
Query: 2701 ILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAKQTAYDATQ 2880
ILATEQAESQPRQVETEYALRTAAERLG HIMQRLEQAAKQTAYDATQ
Sbjct: 901 ILATEQAESQPRQVETEYALRTAAERLGQVTNETTQEQQEQHIMQRLEQAAKQTAYDATQ 960
Query: 2881 TISAANSAK 2907
TISAANSAK
Sbjct: 961 TISAANSAK 969
>gi|39589392|emb|CAE74421.1| Hypothetical protein CBG22153
[Caenorhabditis briggsae]
Length = 990
Score = 1649 bits (4269), Expect = 0.0
Identities = 841/996 (84%), Positives = 880/996 (87%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNANEYGIFRLDENPSKS 180
MGVLSLTVS EKGIKK MQF+PSTL+YDA KLIREKF M D NA+EYG+FR+ P+KS
Sbjct: 1 MGVLSLTVSCQEKGIKKMMQFDPSTLVYDAIKLIREKFGMTDTNAHEYGLFRIGNEPTKS 60
Query: 181 LWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI 360
+WMDNGR+FEHYLVR+KDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI
Sbjct: 61 IWMDNGRSFEHYLVRSKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNKI 120
Query: 361 GISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMRK 540
GISNYEEYSLVRDDILM STWNL +YGTMR+
Sbjct: 121 GISNYEEYSLVRDDILMQNGRDGGGGG-----STWNLKNQENRARSSDRGGG-VYGTMRR 174
Query: 541 KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQL 720
K+E K+EELRKKLHTDEELPWLDH KTLREQ I+EEETL+LRRKYFFSDSNVDSRDPVQL
Sbjct: 175 KDEAKMEELRKKLHTDEELPWLDHQKTLREQAISEEETLVLRRKYFFSDSNVDSRDPVQL 234
Query: 721 NLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFHLDGRDVLPKEYXXX 900
NLLYVQCRDGILRGLHPVEKE A +L ALQSHIQYGDFP+DKPKFHLDGRDVLPKEY
Sbjct: 235 NLLYVQCRDGILRGLHPVEKEKALELGALQSHIQYGDFPHDKPKFHLDGRDVLPKEYAKN 294
Query: 901 XXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV 1080
MYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV
Sbjct: 295 KDNEKKVVAMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRLLGV 354
Query: 1081 NKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIAQLI 1260
NKESVMRVDE +K+ILKEWPLEQVRRWVPS KCF+LDFGDYQDGYYSVQTTDGEKIAQLI
Sbjct: 355 NKESVMRVDEKTKEILKEWPLEQVRRWVPSPKCFTLDFGDYQDGYYSVQTTDGEKIAQLI 414
Query: 1261 QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVAVRG 1440
QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIG+GQHA DGLVAVRG
Sbjct: 415 QGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGNGQHAQDGLVAVRG 474
Query: 1441 VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRAV 1620
VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIR V
Sbjct: 475 VLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTIEATIRTV 534
Query: 1621 EDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXXXXXXXXXXE 1800
E AE ELEAEPQIDIPRFNDD S NRWMEEQ+AVNKENVNERLAAMG E
Sbjct: 535 EQAEEELEAEPQIDIPRFNDDLSANRWMEEQKAVNKENVNERLAAMGAATAQVVQWTAVE 594
Query: 1801 EYDDRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGDLLDATKKLCGAFGKFLNTVNPE 1980
EYDDRVG+AIATIGSNLPDVSRNVRDLGAFME ERGDL+ ATK LCGAFG FL VNPE
Sbjct: 595 EYDDRVGSAIATIGSNLPDVSRNVRDLGAFMEREERGDLVQATKLLCGAFGDFLTAVNPE 654
Query: 1981 TEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKT 2160
RRN+VF AG VGE SQ +IN M+ P++ QQ++D+ LVQ AK+VATSTAQLVLCAKT
Sbjct: 655 QNERRNKVFTAAGRVGEFSQQVINSMDPPSQHQQQYDDYLVQRAKHVATSTAQLVLCAKT 714
Query: 2161 ISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVN 2340
ISA+C+EPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQL+TAATEV+QSVN
Sbjct: 715 ISADCEEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLTTAATEVSQSVN 774
Query: 2341 NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRR 2520
NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKT TTRR+EEEMYNEVLRR
Sbjct: 775 NLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTMTTRRKEEEMYNEVLRR 834
Query: 2521 TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM 2700
TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHR+RLLDAAAKVAHATSEM
Sbjct: 835 TNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEHRDRLLDAAAKVAHATSEM 894
Query: 2701 ILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAKQTAYDATQ 2880
ILATEQAESQPR VETEYALRTAAE LG HIMQRLEQAAKQTAYDATQ
Sbjct: 895 ILATEQAESQPRHVETEYALRTAAENLGKVTNETTKEQQEQHIMQRLEQAAKQTAYDATQ 954
Query: 2881 TISAANSAKKKQQEHKRTETTEQLLVDDSHTILRIR 2988
TISAANS KKKQQEHKRTETTEQLLVDDSHTILRIR
Sbjct: 955 TISAANSTKKKQQEHKRTETTEQLLVDDSHTILRIR 990
>gi|31198901|ref|XP_308398.1| ENSANGP00000019107 [Anopheles gambiae]
gi|21292473|gb|EAA04618.1| ENSANGP00000019107 [Anopheles gambiae str.
PEST]
Length = 2717
Score = 706 bits (1822), Expect = 0.0
Identities = 411/1004 (40%), Positives = 587/1004 (57%), Gaps = 12/1004 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMH-DVNANEYGIFRLDENPSK 177
M LSL +S + KT+QF+PST ++DA ++I++KFA A E+G+F D++ +
Sbjct: 1 MSTLSLRISLEGGRVTKTIQFDPSTTVFDACRIIKDKFAEAVQGQAQEFGLFLADDDTRQ 60
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ R +Y++ N D +EY++K R L+VRMLDGAVKTI VD+SQPVSQLM+ +C K
Sbjct: 61 GVWLEPARNLGYYMLHNHDVLEYRQKHRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTK 120
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N+EEY LVR+D +T L
Sbjct: 121 IGITNHEEYGLVRED-----PEAQNENQPDNRSNTGTLTLRRKA--------------QE 161
Query: 538 KKNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQ 717
K+ + K+E LRKKL TD+E+ W+D KTLREQGI E+ET++LRRK+F+SD N+DSRDPVQ
Sbjct: 162 KERDAKMESLRKKLRTDDEINWVDVGKTLREQGIDEQETVLLRRKFFYSDQNIDSRDPVQ 221
Query: 718 LNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDK--PKFHLDGRDVLPKEY 891
LNLLYVQ RD IL G HPV ++ A + A +Q IQ+GD K P F LD R+ LP Y
Sbjct: 222 LNLLYVQARDAILDGTHPVTQDKACEFAGIQVQIQFGDHNEAKHRPGF-LDLREFLPASY 280
Query: 892 XXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPRL 1071
+++ G S+LDAK +Y R L TYGVTFF+VKEK+ GKNKLVPRL
Sbjct: 281 VRTKNIERKIFAEHRKHVGLSDLDAKYEYTKTARELPTYGVTFFLVKEKMTGKNKLVPRL 340
Query: 1072 LGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKIA 1251
LGV K+SV+R+DE +K+ILK WPL VRRW S F+LDFGDY D YYSVQTT+ E+I
Sbjct: 341 LGVTKDSVLRLDETTKEILKSWPLTTVRRWGASPNTFTLDFGDYADSYYSVQTTEAEQIV 400
Query: 1252 QLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLVA 1431
QLI GY+DIILKKK+ +DH GIEGDEGSTM+E+ VAP+KAT + H + G +A
Sbjct: 401 QLIAGYIDIILKKKQAKDHFGIEGDEGSTMVEESVAPSKATFLQHEETNKGGKVETHSIA 460
Query: 1432 VRGVLRTPQGGQGYG---INGAQYGAVSGEIT-SQELARAQRLRYQDMYQHPQRALIGTI 1599
++R G + YG + QYGA+ G++ + + Q+ R + PQRAL+G I
Sbjct: 461 KPAIMRGTDGERSYGTGEMQSIQYGAIVGQVNLAHQPPMLQQTRISSVLSEPQRALLGYI 520
Query: 1600 EATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXXXX 1779
A A+ AE +LE+ ++ +P D +W EE +K+ V LA M
Sbjct: 521 SAGQDALNRAEKDLES--KVQLPPLGTDPGSLQWREETLDTSKQTVTTHLATMNAATAQV 578
Query: 1780 XXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD-LLDATKKLCGAFG 1953
+E D + VG A++ I ++P+V++ VR + A M+ GD LL+AT+KLC AF
Sbjct: 579 VTASQPDEIDHEAVGAAVSQITQSIPEVTKEVRLIAALMDDDCTGDKLLEATRKLCNAFS 638
Query: 1954 KFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNVATST 2133
L + PE++ R + A VGE S +++ + + ++ + L+ AK VA +T
Sbjct: 639 DLLRSAEPESKEPRQNLLNAATRVGEASGQVLSTIGEESVESRELHDMLLGLAKAVANTT 698
Query: 2134 AQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTA 2313
A LVL AK+I+A ++ + +VI +A++CA ATSQLVACARVV PTI + AC++QL A
Sbjct: 699 AALVLKAKSIAAVTEDEATRNKVIGAASQCALATSQLVACARVVGPTIQSPACREQLEAA 758
Query: 2314 ATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEE 2493
A EV ++V +L A Q D+ AA+ V+ +L LLEH K S + + R E E
Sbjct: 759 AREVAKAVAHLAEVCNEATDNQQLRGDLTAAAKDVSKSLTDLLEHIKLSAREKARRVENE 818
Query: 2494 EMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRPEH--RERLLDA 2667
+ VL T+ +V P E + R+A+++ + + L + + EA + + + +LL+A
Sbjct: 819 NPVDNVLVATDILVSSSDPQE-MIRQAQQLGKATAQLIQSIKGEAESQHDSNMQRKLLEA 877
Query: 2668 AAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXX-XXXXHIMQRLE 2844
A ++A AT+ M+ A P + LRTAAE L ++ RLE
Sbjct: 878 AKQLADATARMVEAARLCAGNPHDSGHQEMLRTAAEELRVITTSTANTPAIKRQLIGRLE 937
Query: 2845 QAAKQTAYDATQTISAANSAKKKQQEHKRTETTEQLLVDDSHTI 2976
Q A+Q A ATQ I+AA ++ H T+++L+ D +
Sbjct: 938 QCARQAASSATQCITAAQNS----LIHSNDVQTKEILLQDCQAV 977
Score = 42.7 bits (99), Expect = 0.051
Identities = 36/123 (29%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +1
Query: 2068 NEGQQKFDERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLV 2247
N+ Q K E L+Q + VA +LV K A D+P Q +I +A +Q+
Sbjct: 962 NDVQTK--EILLQDCQAVADQIPRLVAGVKGTHARPDDPNAQLCLIDAAEMFLEPGAQMA 1019
Query: 2248 ACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHA--VYQQSSLTDIHEAARQVT 2421
AR + PT+ + A QQL ++ +T ++++L A A + L EA R +
Sbjct: 1020 GSARELQPTVMDQAAGQQLGRSSVNLTHAIHDLRLAAHRAREACGGNELDAALEAVRNLR 1079
Query: 2422 SAL 2430
S L
Sbjct: 1080 SVL 1082
>gi|21355751|ref|NP_648238.1| CG6831-PA [Drosophila melanogaster]
gi|7295073|gb|AAF50399.1| CG6831-PA [Drosophila melanogaster]
gi|10764668|gb|AAG22814.1| talin [Drosophila melanogaster]
Length = 2836
Score = 687 bits (1774), Expect = 0.0
Identities = 412/1011 (40%), Positives = 578/1011 (56%), Gaps = 16/1011 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMH-DVNANEYGIFRLDENPSK 177
M LSL + + KT+QF+P+T ++DA K+IR+KFA +EYG+F DE +
Sbjct: 1 MSTLSLRIQLEGGRVTKTIQFQPNTTVFDACKVIRDKFAEAVQGQPSEYGLFISDEQNQQ 60
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ GRT +Y++ N+D +EY+RK R L+VRMLDGAVKTI VD+SQPVSQLM+ +C K
Sbjct: 61 GVWLEPGRTLGYYILHNQDTLEYRRKTRTLRVRMLDGAVKTILVDDSQPVSQLMVVICTK 120
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N+EEY LVR+D N M
Sbjct: 121 IGITNHEEYGLVRED---------------------NEAQNENLPDNKFGTLTLKRKIME 159
Query: 538 KKNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDSRDPVQ 717
K + K+E LRKKL TD+E+ W+D ++TLREQGI E ET++LRR++FFSD N+DSRDPVQ
Sbjct: 160 KDRDAKMESLRKKLKTDDEMNWVDVSRTLREQGIDEAETVLLRRRFFFSDQNIDSRDPVQ 219
Query: 718 LNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKFH---LDGRDVLPKE 888
LNLLYVQ RD IL G HPV ++ A + A +Q HIQ+G P+++ K LD +D LP+
Sbjct: 220 LNLLYVQARDAILDGTHPVTQDKACEFAGIQVHIQFG--PHNEAKHKTGFLDLKDFLPQS 277
Query: 889 YXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKLVPR 1068
Y +++ SE+DAK Y R L TYGVTFF+VKEK+ GKNKLVPR
Sbjct: 278 YVRTKGIEKKIFSEHRKHVDLSEIDAKVLYTKTARELPTYGVTFFLVKEKMNGKNKLVPR 337
Query: 1069 LLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDGEKI 1248
LLGV K+SV+R+DE++K+IL WPL VRRW S F+LDFGDY + YYSVQTT+ E+I
Sbjct: 338 LLGVTKDSVLRLDEHTKEILISWPLTTVRRWGASPNTFTLDFGDYANQYYSVQTTEAEQI 397
Query: 1249 AQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATDGLV 1428
QLI GY+DIILKKK+T+DH GIEGDEGSTM+E+ VAP+KAT + H Q + L
Sbjct: 398 VQLIAGYIDIILKKKQTKDHFGIEGDEGSTMVEESVAPSKATFLQHETNRMEQLNVESL- 456
Query: 1429 AVRGVLRTPQGGQGY---GINGAQYGAVSGEIT-SQELARAQRLRYQDM-YQHPQRALIG 1593
A G++R G + Y + QYGA G++ + + + +R + PQRAL+G
Sbjct: 457 AHPGIMRPYDGERSYMENEVQTVQYGAFVGQVNHAHQPPTTKEVRISSVNLTEPQRALLG 516
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXX 1773
I A + A+ EL + I D W E +K+ V+ +A M
Sbjct: 517 YISAGQDVLIRADEELRTKAPIQ--ELGSDLRSIEWRENTLDTSKQAVSSHVATMSAATA 574
Query: 1774 XXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD-LLDATKKLCGA 1947
+E D + + +++ I +P+V++ VR + A ME+ GD LL+A + LC A
Sbjct: 575 QIITASHPDEVDTEAISASVSQIAQTIPEVTKEVRLIAALMENDTSGDQLLEAARNLCSA 634
Query: 1948 FGKFLNTVNPETEARRNEVFRTAGHVGETSQHLIN-VMEAPNEGQQKFDERLVQSAKNVA 2124
F L PE++ + A VGE + H+++ + E + + L+ AK VA
Sbjct: 635 FSDLLKAAEPESKEPPQHLINAASRVGEATTHVLSTIAEEEVPENRDLHDMLLALAKAVA 694
Query: 2125 TSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQL 2304
+TA LVL AK I+A CD+ Q + RVI +A++CA ATSQLVACA+VVAPT+ N AC++QL
Sbjct: 695 NTTAALVLRAKNIAASCDDEQARNRVIGAASQCALATSQLVACAKVVAPTLHNAACREQL 754
Query: 2305 STAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRR 2484
AA V ++VN+L A D+ AAR V+ +L +LEH K S + R
Sbjct: 755 EAAAKNVARAVNSLCEVCNEASNDPKLKADLLAAARDVSKSLTDMLEHVKLSSREHANRT 814
Query: 2485 EEE-EMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQR--PEHRER 2655
E V+ T+ +V P E + R AR + + + L + + EA Q+ + +
Sbjct: 815 STELSPVENVIIGTDILVSTHDPQE-MVRHARTLGQTTAQLIQSIKGEADQQQDADMKRH 873
Query: 2656 LLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXH-IM 2832
LL AA ++A AT++++ A S P + + ALR AAE L ++
Sbjct: 874 LLSAAKQLADATAKLVEAARLCSSNPHDSDNQNALRKAAEELREITTTAANTPAMKRGLI 933
Query: 2833 QRLEQAAKQTAYDATQTISAANSAKKKQQEHKRTETTEQLLVDDSHTILRI 2985
QRLE +KQ A ATQ ISAA +A + Q+H+ ET Q + TI R+
Sbjct: 934 QRLEFCSKQAASAATQCISAAQNAVQHSQDHQTKETLLQDCKRVADTIPRL 984
Score = 47.0 bits (110), Expect = 0.003
Identities = 32/106 (30%), Positives = 52/106 (48%)
Frame = +1
Query: 2050 NVMEAPNEGQQKFDERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAF 2229
N ++ + Q K E L+Q K VA + +LV KT A+ D+P Q +I++A +
Sbjct: 956 NAVQHSQDHQTK--ETLLQDCKRVADTIPRLVTSLKTTRAQPDDPNAQLNLIEAAEQFIE 1013
Query: 2230 ATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHA 2367
Q+ +R + PT+ + QLS A + Q V+ L A+ A
Sbjct: 1014 PALQVSKSSRALQPTVTDIPSATQLSKGALHLGQCVSELHSVAQRA 1059
Score = 44.3 bits (103), Expect = 0.018
Identities = 39/164 (23%), Positives = 68/164 (40%), Gaps = 5/164 (3%)
Frame = +1
Query: 1960 LNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNE-----GQQKFDERLVQSAKNVA 2124
+NT NP +NE A V + L+ ++A E +++ + L+++ K V
Sbjct: 1524 MNTSNP---VAKNEFIVLAKQVATATSDLVQDIKAIEEQSAGGSRERLVDPLLEAVKAVR 1580
Query: 2125 TSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQL 2304
+ + + + QE VIQ+ ++V A+ +A T DN QQL
Sbjct: 1581 QYASSSEFSSVPAKISAEGRKAQEPVIQAGRGVIDGVVEMVKAAKSLALTPDNPPVWQQL 1640
Query: 2305 STAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDS 2436
S +T V++SV L+ + Q+ + T LDS
Sbjct: 1641 SMHSTPVSESVKRLVDNIRDKAPGQAQCEQVLHTLGTCTRELDS 1684
>gi|6739602|gb|AAF27330.1| talin [Homo sapiens]
Length = 2540
Score = 663 bits (1710), Expect = 0.0
Identities = 397/985 (40%), Positives = 576/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ I GT+R
Sbjct: 119 IGITNHDEYSLVRE--------------------------------LMEEKKEEITGTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFD--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGSGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDALMQLAK 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 47.4 bits (111), Expect = 0.002
Identities = 60/269 (22%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Frame = +1
Query: 2065 PNEGQQKFDERLVQSAKNVATSTAQLV--------------------------LCAKTIS 2166
P E +K + L S K V+++ AQL+ A+ ++
Sbjct: 1080 PGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVA 1139
Query: 2167 AECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNL 2346
A +P VQ V+ +A+ S L+ A+ A + QQ+L+ A VTQ++N
Sbjct: 1140 ALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN-- 1197
Query: 2347 LHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTN 2526
V D+ A R V A LL + P + T +E + NE N
Sbjct: 1198 -----RCVSCLPGQRDVDNALRAVGDASKRLLSDS--LPPSTGTFQEAQSRLNEAAAGLN 1250
Query: 2527 RMVVH-----QGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRERLLDAAAKVAH 2685
+ +G +DL R + + + E A Q P E R +++ ++
Sbjct: 1251 QAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISM 1310
Query: 2686 ATSEMILATEQAESQPRQVETEYALRTAA 2772
++S+++LA + + P + L AA
Sbjct: 1311 SSSKLLLAAKALSTDPAAPNLKSQLAAAA 1339
Score = 43.9 bits (102), Expect = 0.023
Identities = 59/241 (24%), Positives = 95/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEVKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V V QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
Score = 35.4 bits (80), Expect = 8.2
Identities = 67/304 (22%), Positives = 119/304 (39%), Gaps = 34/304 (11%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTI-SAECDEPQVQERVIQSA------TKCAFATS-QLVA 2250
+ VQSAK VA STA LV K + A +E + Q R + AFA++ + +
Sbjct: 1524 QFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSS 1583
Query: 2251 CARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVY---QQSSLTDIHEAARQVT 2421
++P + A + + +A + +S L+ A S + + +R V+
Sbjct: 1584 IPAQISP--EGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVS 1641
Query: 2422 SALDSLLEHAKCSPKTQTTRREEEEMYNEVLR---RTNRMVVHQ--GPSEDLTREARKVV 2586
++ L+ + Q N LR + + V Q P E +++EA
Sbjct: 1642 DSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA---- 1697
Query: 2587 RHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------ILATEQAESQP 2733
H+Q+LT Q +H A+++ H S+M + A + S P
Sbjct: 1698 LHTQMLT-AVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHP 1756
Query: 2734 RQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTAYDATQTISA 2892
+Q+ +T+ +A + L H + LE+A + + D T T++
Sbjct: 1757 QQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNE 1816
Query: 2893 ANSA 2904
A SA
Sbjct: 1817 AASA 1820
>gi|20521736|dbj|BAA82979.2| KIAA1027 protein [Homo sapiens]
Length = 2550
Score = 663 bits (1710), Expect = 0.0
Identities = 397/985 (40%), Positives = 576/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 10 MVALSLKISIGN--VVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 67
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 68 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 127
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ I GT+R
Sbjct: 128 IGITNHDEYSLVRE--------------------------------LMEEKKEEITGTLR 155
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 156 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 215
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 216 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 275
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 276 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 334
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 335 VPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 394
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 395 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 453
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 454 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 506
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 507 TINSSMQAVQAAQATLDDFD--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 564
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G LL A K
Sbjct: 565 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGSGRPLLQAAKG 623
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 624 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDALMQLAK 682
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 683 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 742
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 743 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 802
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 803 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 862
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 863 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 922
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 923 VQRLEHAAKQAAASATQTIAAAQHA 947
Score = 47.4 bits (111), Expect = 0.002
Identities = 60/269 (22%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Frame = +1
Query: 2065 PNEGQQKFDERLVQSAKNVATSTAQLV--------------------------LCAKTIS 2166
P E +K + L S K V+++ AQL+ A+ ++
Sbjct: 1089 PGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVA 1148
Query: 2167 AECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNL 2346
A +P VQ V+ +A+ S L+ A+ A + QQ+L+ A VTQ++N
Sbjct: 1149 ALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN-- 1206
Query: 2347 LHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTN 2526
V D+ A R V A LL + P + T +E + NE N
Sbjct: 1207 -----RCVSCLPGQRDVDNALRAVGDASKRLLSDS--LPPSTGTFQEAQSRLNEAAAGLN 1259
Query: 2527 RMVVH-----QGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRERLLDAAAKVAH 2685
+ +G +DL R + + + E A Q P E R +++ ++
Sbjct: 1260 QAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISM 1319
Query: 2686 ATSEMILATEQAESQPRQVETEYALRTAA 2772
++S+++LA + + P + L AA
Sbjct: 1320 SSSKLLLAAKALSTDPAAPNLKSQLAAAA 1348
Score = 43.9 bits (102), Expect = 0.023
Identities = 59/241 (24%), Positives = 95/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 961 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1020
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1021 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEVKA 1078
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V V QG AR V +
Sbjct: 1079 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLR 1138
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1139 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVA 1198
Query: 2773 E 2775
+
Sbjct: 1199 K 1199
Score = 35.4 bits (80), Expect = 8.2
Identities = 67/304 (22%), Positives = 119/304 (39%), Gaps = 34/304 (11%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTI-SAECDEPQVQERVIQSA------TKCAFATS-QLVA 2250
+ VQSAK VA STA LV K + A +E + Q R + AFA++ + +
Sbjct: 1533 QFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSS 1592
Query: 2251 CARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVY---QQSSLTDIHEAARQVT 2421
++P + A + + +A + +S L+ A S + + +R V+
Sbjct: 1593 IPAQISP--EGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVS 1650
Query: 2422 SALDSLLEHAKCSPKTQTTRREEEEMYNEVLR---RTNRMVVHQ--GPSEDLTREARKVV 2586
++ L+ + Q N LR + + V Q P E +++EA
Sbjct: 1651 DSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA---- 1706
Query: 2587 RHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------ILATEQAESQP 2733
H+Q+LT Q +H A+++ H S+M + A + S P
Sbjct: 1707 LHTQMLT-AVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHP 1765
Query: 2734 RQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTAYDATQTISA 2892
+Q+ +T+ +A + L H + LE+A + + D T T++
Sbjct: 1766 QQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNE 1825
Query: 2893 ANSA 2904
A SA
Sbjct: 1826 AASA 1829
>gi|27552808|gb|AAH42923.1| Talin 1 [Homo sapiens]
Length = 2541
Score = 663 bits (1710), Expect = 0.0
Identities = 397/985 (40%), Positives = 576/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ I GT+R
Sbjct: 119 IGITNHDEYSLVRE--------------------------------LMEEKKEEITGTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFD--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGSGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDALMQLAK 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 47.4 bits (111), Expect = 0.002
Identities = 60/269 (22%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Frame = +1
Query: 2065 PNEGQQKFDERLVQSAKNVATSTAQLV--------------------------LCAKTIS 2166
P E +K + L S K V+++ AQL+ A+ ++
Sbjct: 1080 PGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVA 1139
Query: 2167 AECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNL 2346
A +P VQ V+ +A+ S L+ A+ A + QQ+L+ A VTQ++N
Sbjct: 1140 ALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN-- 1197
Query: 2347 LHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTN 2526
V D+ A R V A LL + P + T +E + NE N
Sbjct: 1198 -----RCVSCLPGQRDVDNALRAVGDASKRLLSDS--LPPSTGTFQEAQSRLNEAAAGLN 1250
Query: 2527 RMVVH-----QGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRERLLDAAAKVAH 2685
+ +G +DL R + + + E A Q P E R +++ ++
Sbjct: 1251 QAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISM 1310
Query: 2686 ATSEMILATEQAESQPRQVETEYALRTAA 2772
++S+++LA + + P + L AA
Sbjct: 1311 SSSKLLLAAKALSTDPAAPNLKSQLAAAA 1339
Score = 43.9 bits (102), Expect = 0.023
Identities = 59/241 (24%), Positives = 95/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEVKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V V QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
Score = 35.4 bits (80), Expect = 8.2
Identities = 67/304 (22%), Positives = 119/304 (39%), Gaps = 34/304 (11%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTI-SAECDEPQVQERVIQSA------TKCAFATS-QLVA 2250
+ VQSAK VA STA LV K + A +E + Q R + AFA++ + +
Sbjct: 1524 QFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSS 1583
Query: 2251 CARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVY---QQSSLTDIHEAARQVT 2421
++P + A + + +A + +S L+ A S + + +R V+
Sbjct: 1584 IPAQISP--EGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVS 1641
Query: 2422 SALDSLLEHAKCSPKTQTTRREEEEMYNEVLR---RTNRMVVHQ--GPSEDLTREARKVV 2586
++ L+ + Q N LR + + V Q P E +++EA
Sbjct: 1642 DSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA---- 1697
Query: 2587 RHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------ILATEQAESQP 2733
H+Q+LT Q +H A+++ H S+M + A + S P
Sbjct: 1698 LHTQMLT-AVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHP 1756
Query: 2734 RQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTAYDATQTISA 2892
+Q+ +T+ +A + L H + LE+A + + D T T++
Sbjct: 1757 QQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNE 1816
Query: 2893 ANSA 2904
A SA
Sbjct: 1817 AASA 1820
>gi|49022858|dbj|BAC65702.4| mKIAA1027 protein [Mus musculus]
Length = 2564
Score = 662 bits (1709), Expect = 0.0
Identities = 399/985 (40%), Positives = 578/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ N++G+F D++P K
Sbjct: 24 MVALSLKISIGN--VVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKK 81
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 82 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 141
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ LM GT+R
Sbjct: 142 IGITNHDEYSLVRE--LMEEKKDEGT------------------------------GTLR 169
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 170 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 229
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 230 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 289
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 290 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 348
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 349 VPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 408
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 409 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 467
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 468 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 520
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 521 TINSSMQAVQAAQATLDDFE--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 578
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G+ LL A K
Sbjct: 579 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGNGRPLLQAAKG 637
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 638 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDVLMQLAK 696
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 697 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 756
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 757 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 816
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 817 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 876
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 877 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 936
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 937 VQRLEHAAKQAAASATQTIAAAQHA 961
Score = 43.5 bits (101), Expect = 0.030
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 975 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1034
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1035 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEIKA 1092
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V + QG AR V +
Sbjct: 1093 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYAGIAARDVAGGLR 1152
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1153 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVA 1212
Query: 2773 E 2775
+
Sbjct: 1213 K 1213
Score = 36.2 bits (82), Expect = 4.8
Identities = 60/295 (20%), Positives = 115/295 (38%), Gaps = 11/295 (3%)
Frame = +1
Query: 1912 DLLDATKKLCGAFGKFLNTVNPETEARRNEVFR-TAGHVGETSQHLINVMEAPNEGQQKF 2088
DL ++TK + A K L + E R AG + +Q V ++
Sbjct: 1113 DLGNSTKAVSSAIAKLLGEIAQGNENYAGIAARDVAGGLRSLAQAARGVAALTSD--PAV 1170
Query: 2089 DERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVA 2268
++ +A +V + L+ AK S +P+ Q+R+ Q A A ++ V+C
Sbjct: 1171 QAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVAKAVTQALNRCVSCL---- 1226
Query: 2269 PTIDNNACQQQLSTAATEVTQSVNNLLHDA---EHAVYQQSSLTDIHEAARQVTSALDSL 2439
Q+ + A V + LL D+ +Q++ + ++EAA + A L
Sbjct: 1227 ------PGQRDVDNALRAVGDASKRLLSDSLPPSTGTFQEAQ-SRLNEAAAGLNQAATEL 1279
Query: 2440 LEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVR------HSQL 2601
++ ++ +P+ + Q PS++ + +++ L
Sbjct: 1280 VQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSILKGISMSSSKLL 1339
Query: 2602 LTEQFQHEAHQRPEHRERLLDAAAKVAHATSEMI-LATEQAESQPRQVETEYALR 2763
L + P + +L AA V + +++I + T+QA P Q E + ALR
Sbjct: 1340 LAAKALSTDPASPNLKSQLAAAARAVTDSINQLITMCTQQA---PGQKECDNALR 1391
Score = 35.4 bits (80), Expect = 8.2
Identities = 63/313 (20%), Positives = 112/313 (35%), Gaps = 43/313 (13%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPT 2274
+ VQSAK VA STA LV K + + E ++ +C AT+ L+ ++
Sbjct: 1547 QFVQSAKEVANSTANLVKTIKALDGDFTE--------ENRAQCRAATAPLLEAVDNLSAF 1598
Query: 2275 IDN--------------NACQQQLSTAATEVTQSVNNLLHDA-----------EHAVYQQ 2379
N A + + +A + +S L+ A +V
Sbjct: 1599 ASNPEFSSVPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAG 1658
Query: 2380 SSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSED 2559
S T + +TS D +C ++ L ++ + P E
Sbjct: 1659 HSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQL---APREG 1715
Query: 2560 LTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------IL 2706
+++EA H+Q+LT Q +H A+++ H S+M +
Sbjct: 1716 ISQEA----LHTQMLT-AVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVG 1770
Query: 2707 ATEQAESQPRQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTA 2865
A + S P+Q+ +T+ +A + L H + LE+A + +
Sbjct: 1771 AASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAV 1830
Query: 2866 YDATQTISAANSA 2904
D T T++ A SA
Sbjct: 1831 EDLTTTLNEAASA 1843
>gi|6755809|ref|NP_035732.1| talin [Mus musculus]
gi|135290|sp|P26039|TLN1_MOUSE Talin 1
gi|111127|pir||S11661 talin - mouse
gi|54258|emb|CAA39588.1| talin [Mus musculus]
Length = 2541
Score = 660 bits (1704), Expect = 0.0
Identities = 398/985 (40%), Positives = 577/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ N++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ LM GT+R
Sbjct: 119 IGITNHDEYSLVRE--LMEEKKDEGT------------------------------GTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFE--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G+ LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGNGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q A
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDVLMQLAN 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 43.5 bits (101), Expect = 0.030
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEIKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V + QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
Score = 35.4 bits (80), Expect = 8.2
Identities = 63/313 (20%), Positives = 112/313 (35%), Gaps = 43/313 (13%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPT 2274
+ VQSAK VA STA LV K + + E ++ +C AT+ L+ ++
Sbjct: 1524 QFVQSAKEVANSTANLVKTIKALDGDFTE--------ENRAQCRAATAPLLEAVDNLSAF 1575
Query: 2275 IDN--------------NACQQQLSTAATEVTQSVNNLLHDA-----------EHAVYQQ 2379
N A + + +A + +S L+ A +V
Sbjct: 1576 ASNPEFSSVPAQISPEGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPRWSVLAG 1635
Query: 2380 SSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSED 2559
S T + +TS D +C ++ L ++ + P E
Sbjct: 1636 HSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQL---APREG 1692
Query: 2560 LTREARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------IL 2706
+++EA H+Q+LT Q +H A+++ H S+M +
Sbjct: 1693 ISQEA----LHTQMLT-AVQEISHLIEPLASAARAEASQLGHKVSQMAQYFEPLTLAAVG 1747
Query: 2707 ATEQAESQPRQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTA 2865
A + S P+Q+ +T+ +A + L H + LE+A + +
Sbjct: 1748 AASKTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAV 1807
Query: 2866 YDATQTISAANSA 2904
D T T++ A SA
Sbjct: 1808 EDLTTTLNEAASA 1820
>gi|227256|prf||1617167A talin
Length = 2541
Score = 660 bits (1704), Expect = 0.0
Identities = 398/985 (40%), Positives = 577/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ N++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRMIRERIPEALAGPPNDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ LM GT+R
Sbjct: 119 IGITNHDEYSLVRE--LMEEKKDEGT------------------------------GTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFE--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G+ LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGNGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q A
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDVLMQLAN 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 43.5 bits (101), Expect = 0.030
Identities = 58/241 (24%), Positives = 95/241 (39%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEIKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V + QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKASGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
>gi|4235275|gb|AAD13152.1| talin [Homo sapiens]
Length = 2541
Score = 660 bits (1703), Expect = 0.0
Identities = 396/985 (40%), Positives = 575/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ I GT+R
Sbjct: 119 IGITNHDEYSLVRE--------------------------------LMEEKKEEITGTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFD--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGSGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDALMQLAK 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ +AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVGQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 47.0 bits (110), Expect = 0.003
Identities = 60/269 (22%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Frame = +1
Query: 2065 PNEGQQKFDERLVQSAKNVATSTAQLV--------------------------LCAKTIS 2166
P E +K + L S K V+++ AQL+ A+ ++
Sbjct: 1080 PGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVA 1139
Query: 2167 AECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNL 2346
A +P VQ V+ +A+ S L+ A+ A + QQ+L+ A VTQ++N
Sbjct: 1140 ALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN-- 1197
Query: 2347 LHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTN 2526
V D+ A R V A LL + P + T +E + NE N
Sbjct: 1198 -----RCVSCLPGQRDVDNALRAVGDASKRLL--SDLLPPSTGTFQEAQSRLNEAAAGLN 1250
Query: 2527 RMVVH-----QGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRERLLDAAAKVAH 2685
+ +G +DL R + + + E A Q P E R +++ ++
Sbjct: 1251 QAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISM 1310
Query: 2686 ATSEMILATEQAESQPRQVETEYALRTAA 2772
++S+++LA + + P + L AA
Sbjct: 1311 SSSKLLLAAKALSTDPAAPNLKSQLAAAA 1339
Score = 43.9 bits (102), Expect = 0.023
Identities = 59/241 (24%), Positives = 95/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEVKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V V QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
Score = 35.8 bits (81), Expect = 6.3
Identities = 69/310 (22%), Positives = 118/310 (37%), Gaps = 40/310 (12%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPT 2274
+ VQSAK VA STA LV KTI A D P +E + +C AT+ L+ ++
Sbjct: 1524 QFVQSAKEVANSTANLV---KTIKA-LDGPFTEE----NRAQCRAATAPLLEAVDNLSAF 1575
Query: 2275 IDN--------------NACQQQLSTAATEVTQSVNNLLHDAEHAVY---QQSSLTDIHE 2403
N A + + +A + +S L+ A S + +
Sbjct: 1576 ASNPEFSSIPAQISPEGRAAMEPIVISAQTMLESAGGLIQTARALAVNPRDPPSWSVLAG 1635
Query: 2404 AARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLR---RTNRMVVHQ--GPSEDLTR 2568
+R V+ ++ L+ + Q N LR + + V Q P E +++
Sbjct: 1636 HSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQ 1695
Query: 2569 EARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------ILATE 2715
EA H+++LT Q +H A+++ H S+M + A
Sbjct: 1696 EA----LHTEMLT-AVQEISHLIEPLAHAARAEASQLGHKVSQMAQYFEPLTLAAVGAAS 1750
Query: 2716 QAESQPRQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTAYDA 2874
+ S P+Q+ +T+ +A + L H + LE+A + + D
Sbjct: 1751 KTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDL 1810
Query: 2875 TQTISAANSA 2904
T T++ A SA
Sbjct: 1811 TTTLNEAASA 1820
>gi|16753233|ref|NP_006280.2| talin 1 [Homo sapiens]
Length = 2541
Score = 660 bits (1703), Expect = 0.0
Identities = 396/985 (40%), Positives = 575/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ I GT+R
Sbjct: 119 IGITNHDEYSLVRE--------------------------------LMEEKKEEITGTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFD--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGSGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDALMQLAK 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ +AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVGQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 47.4 bits (111), Expect = 0.002
Identities = 60/269 (22%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Frame = +1
Query: 2065 PNEGQQKFDERLVQSAKNVATSTAQLV--------------------------LCAKTIS 2166
P E +K + L S K V+++ AQL+ A+ ++
Sbjct: 1080 PGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVA 1139
Query: 2167 AECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNL 2346
A +P VQ V+ +A+ S L+ A+ A + QQ+L+ A VTQ++N
Sbjct: 1140 ALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN-- 1197
Query: 2347 LHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTN 2526
V D+ A R V A LL + P + T +E + NE N
Sbjct: 1198 -----RCVSCLPGQRDVDNALRAVGDASKRLLSDS--LPPSTGTFQEAQSRLNEAAAGLN 1250
Query: 2527 RMVVH-----QGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRERLLDAAAKVAH 2685
+ +G +DL R + + + E A Q P E R +++ ++
Sbjct: 1251 QAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISM 1310
Query: 2686 ATSEMILATEQAESQPRQVETEYALRTAA 2772
++S+++LA + + P + L AA
Sbjct: 1311 SSSKLLLAAKALSTDPAAPNLKSQLAAAA 1339
Score = 43.9 bits (102), Expect = 0.023
Identities = 59/241 (24%), Positives = 95/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEVKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V V QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
Score = 35.4 bits (80), Expect = 8.2
Identities = 67/304 (22%), Positives = 119/304 (39%), Gaps = 34/304 (11%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTI-SAECDEPQVQERVIQSA------TKCAFATS-QLVA 2250
+ VQSAK VA STA LV K + A +E + Q R + AFA++ + +
Sbjct: 1524 QFVQSAKEVANSTANLVKTIKALDGAFTEENRAQCRAATAPLLEAVDNLSAFASNPEFSS 1583
Query: 2251 CARVVAPTIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVY---QQSSLTDIHEAARQVT 2421
++P + A + + +A + +S L+ A S + + +R V+
Sbjct: 1584 IPAQISP--EGRAAMEPIVISAKTMLESAGGLIQTARALAVNPRDPPSWSVLAGHSRTVS 1641
Query: 2422 SALDSLLEHAKCSPKTQTTRREEEEMYNEVLR---RTNRMVVHQ--GPSEDLTREARKVV 2586
++ L+ + Q N LR + + V Q P E +++EA
Sbjct: 1642 DSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQEA---- 1697
Query: 2587 RHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------ILATEQAESQP 2733
H+Q+LT Q +H A+++ H S+M + A + S P
Sbjct: 1698 LHTQMLT-AVQEISHLIEPLANAARAEASQLGHKVSQMAQYFEPLTLAAVGAASKTLSHP 1756
Query: 2734 RQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTAYDATQTISA 2892
+Q+ +T+ +A + L H + LE+A + + D T T++
Sbjct: 1757 QQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDLTTTLNE 1816
Query: 2893 ANSA 2904
A SA
Sbjct: 1817 AASA 1820
>gi|14916725|sp|Q9Y490|TLN1_HUMAN Talin 1
gi|6682361|gb|AAF23322.1| talin [Homo sapiens]
Length = 2541
Score = 660 bits (1703), Expect = 0.0
Identities = 396/985 (40%), Positives = 575/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRIIRERIPEAPAGPPSDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ I GT+R
Sbjct: 119 IGITNHDEYSLVRE--------------------------------LMEEKKEEITGTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWNLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKVEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A +ITS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQITSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D + W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQATLDDFD--TLPPLGQDAASKAWRKNKMDESKHEIHSQVDAITAGTA 555
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G LL A K
Sbjct: 556 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGSGRPLLQAAKG 614
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 615 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDALMQLAK 673
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 674 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 733
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 734 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 793
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ +AR + + + L + +A E+
Sbjct: 794 PAGRYDQATDTILTVTENIFSSMGDAGEMVGQARILAQATSDLVNAIKADAEGESDLENS 853
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 854 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 913
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 914 VQRLEHAAKQAAASATQTIAAAQHA 938
Score = 47.4 bits (111), Expect = 0.002
Identities = 60/269 (22%), Positives = 104/269 (38%), Gaps = 33/269 (12%)
Frame = +1
Query: 2065 PNEGQQKFDERLVQSAKNVATSTAQLV--------------------------LCAKTIS 2166
P E +K + L S K V+++ AQL+ A+ ++
Sbjct: 1080 PGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLRSLAQAARGVA 1139
Query: 2167 AECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQLSTAATEVTQSVNNL 2346
A +P VQ V+ +A+ S L+ A+ A + QQ+L+ A VTQ++N
Sbjct: 1140 ALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVAKAVTQALN-- 1197
Query: 2347 LHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLRRTN 2526
V D+ A R V A LL + P + T +E + NE N
Sbjct: 1198 -----RCVSCLPGQRDVDNALRAVGDASKRLLSDS--LPPSTGTFQEAQSRLNEAAAGLN 1250
Query: 2527 RMVVH-----QGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRERLLDAAAKVAH 2685
+ +G +DL R + + + E A Q P E R +++ ++
Sbjct: 1251 QAATELVQASRGTPQDLARASGRFGQDFSTFLEAGVEMAGQAPSQEDRAQVVSNLKGISM 1310
Query: 2686 ATSEMILATEQAESQPRQVETEYALRTAA 2772
++S+++LA + + P + L AA
Sbjct: 1311 SSSKLLLAAKALSTDPAAPNLKSQLAAAA 1339
Score = 43.9 bits (102), Expect = 0.023
Identities = 59/241 (24%), Positives = 95/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 952 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1011
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1012 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEVKA 1069
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V V QG AR V +
Sbjct: 1070 AARDGKLKPLPGETMEKCTQDLGNSTKAVSSAIAQLLGEVAQGNENYAGIAARDVAGGLR 1129
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ V S +I ++A P E++ L A
Sbjct: 1130 SLAQAARGVAALTSDPAVQAIVLDTASDVLDKASSLIEEAKKAAGHPGDPESQQRLAQVA 1189
Query: 2773 E 2775
+
Sbjct: 1190 K 1190
Score = 35.8 bits (81), Expect = 6.3
Identities = 69/310 (22%), Positives = 118/310 (37%), Gaps = 40/310 (12%)
Frame = +1
Query: 2095 RLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPT 2274
+ VQSAK VA STA LV KTI A D P +E + +C AT+ L+ ++
Sbjct: 1524 QFVQSAKEVANSTANLV---KTIKA-LDGPFTEE----NRAQCRAATAPLLEAVDNLSAF 1575
Query: 2275 IDN--------------NACQQQLSTAATEVTQSVNNLLHDAEHAVY---QQSSLTDIHE 2403
N A + + +A + +S L+ A S + +
Sbjct: 1576 ASNPEFSSIPAQISPEGRAAMEPIVISAQTMLESAGGLIQTARALAVNPRDPPSWSVLAG 1635
Query: 2404 AARQVTSALDSLLEHAKCSPKTQTTRREEEEMYNEVLR---RTNRMVVHQ--GPSEDLTR 2568
+R V+ ++ L+ + Q N LR + + V Q P E +++
Sbjct: 1636 HSRTVSDSIKKLITSMRDKAPGQLECETAIAALNSCLRDLDQASLAAVSQQLAPREGISQ 1695
Query: 2569 EARKVVRHSQLLTEQFQHEAHQRPEHRERLLDAAAKVAHATSEM-----------ILATE 2715
EA H+++LT Q +H A+++ H S+M + A
Sbjct: 1696 EA----LHTEMLT-AVQEISHLIEPLAHAARAEASQLGHKVSQMAQYFEPLTLAAVGAAS 1750
Query: 2716 QAESQPRQV----ETEYALRTAAERLGXXXXXXXXXXXXXHIMQRLEQAAK---QTAYDA 2874
+ S P+Q+ +T+ +A + L H + LE+A + + D
Sbjct: 1751 KTLSHPQQMALLDQTKTLAESALQLLYTAKEAGGNPKQAAHTQEALEEAVQMMTEAVEDL 1810
Query: 2875 TQTISAANSA 2904
T T++ A SA
Sbjct: 1811 TTTLNEAASA 1820
>gi|45383127|ref|NP_989854.1| talin [Gallus gallus]
gi|26000436|gb|AAN75275.1| talin [Gallus gallus]
Length = 2541
Score = 660 bits (1702), Expect = 0.0
Identities = 396/983 (40%), Positives = 567/983 (57%), Gaps = 15/983 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ + N++G+F DE+P K
Sbjct: 1 MVALSLKISIGN--VVKTMQFEPSTMVYDACRMIRERVPEAQMGQPNDFGLFLSDEDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EYK+K R LK+RMLDG VKT+ VD+S+ V+ ++ T+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYKKKQRPLKIRMLDGTVKTVMVDDSKTVTDMLTTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+NY+EYSLVR+ + + GT++
Sbjct: 119 IGITNYDEYSLVREIM--------------------------------EEKKEEVTGTLK 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQGI + ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGIDDNETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPK-FHLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K L+ +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGYQCQIQFGPHNEQKHKPGFLELKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYIKQKGERKIFMA-HKNCGNMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATD 1419
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T V Q A
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKST-VLQQQFNRVGKAEL 444
Query: 1420 GLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIGTI 1599
G VA+ ++RT GG G A +ITS ++ R + Q+AL GTI
Sbjct: 445 GSVALPAIMRTGAGGPENFQVGTMPQA-QMQITSGQMHRG----HMPPLTSAQQALTGTI 499
Query: 1600 EATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXXXX 1779
++++AV A+ L+ +P D + W + + +K ++ + A+
Sbjct: 500 NSSMQAVNAAQATLDDFE--TLPPLGQDAASKAWRKNKMDESKHEIHSQADAITAGTASV 557
Query: 1780 XXXXXXEEYD---DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKKLC 1941
+ D VG A+ TI SNL ++S+ V+ L A ME E G+ LL A K L
Sbjct: 558 VNLTAGDPADTDYTAVGCAVTTISSNLTEMSKGVKLLAALMED-EGGNGRQLLQAAKNLA 616
Query: 1942 GAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKNV 2121
A L T P + R + + AG VG+TS L+ + ++ +F + L+Q AK V
Sbjct: 617 SAVSDLLKTAQPASAEPRQNLLQAAGLVGQTSGELLQQI-GESDTDPRFQDMLMQLAKAV 675
Query: 2122 ATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQQ 2301
A++ A LVL AK ++ + ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ+Q
Sbjct: 676 ASAAAALVLKAKNVAQKTEDSALQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQEQ 735
Query: 2302 LSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTTR 2481
L A V +S + ++ A L + AA VT AL+ LL+H K
Sbjct: 736 LIEAGKLVAKSAEGCVEASKAATNDDQLLKQVGVAATAVTQALNDLLQHIKQHATGGQPI 795
Query: 2482 REEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHRER 2655
++ + +L T + G + ++ R+AR + + + L + +A E+ +
Sbjct: 796 GRYDQATDTILNVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGETDLENSRK 855
Query: 2656 LLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIMQ 2835
LL AA +A AT++M+ A + A + P E + LR AAE L ++
Sbjct: 856 LLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKLVH 915
Query: 2836 RLEQAAKQTAYDATQTISAANSA 2904
+LE AAKQ A ATQTI+AA A
Sbjct: 916 KLEHAAKQAAASATQTIAAAQHA 938
Score = 47.4 bits (111), Expect = 0.002
Identities = 53/243 (21%), Positives = 106/243 (42%), Gaps = 15/243 (6%)
Frame = +1
Query: 2092 ERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAP 2271
++LVQS K VA LV + ++ D P Q +I ++ ++VA A+ P
Sbjct: 949 QQLVQSCKVVADQIPMLVQGVRGSQSQPDSPSAQLALIAASQNFLQPGGKMVAAAKATVP 1008
Query: 2272 TIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHA 2451
TI + A QLS A + ++ L A+ A Q++ ++A + +L+ L+ A
Sbjct: 1009 TITDQASAMQLSQCAKNLAAALAELRTAAQKA--QEACGPLEIDSALGLVQSLERDLKEA 1066
Query: 2452 KCSPKT--------QTTRREEEEMYNEVLRRTNRMV-----VHQGPSEDLTREARKVVRH 2592
K + + +T + +++ N T+ + V QG AR+V +
Sbjct: 1067 KAAARDGKLKPLPGETMEKCAQDLGNSTKAVTSAIAHLLGEVAQGNENYTGIAAREVAQA 1126
Query: 2593 SQLLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRT 2766
+ L++ + A P+ + +L+ A+ V + +I +A ++P +++ L
Sbjct: 1127 LRSLSQAARGVAANSSDPQAQNAMLECASDVMDKANNLIEEARKAVAKPGDPDSQQRLVQ 1186
Query: 2767 AAE 2775
A+
Sbjct: 1187 VAK 1189
Score = 35.8 bits (81), Expect = 6.3
Identities = 27/81 (33%), Positives = 43/81 (52%), Gaps = 2/81 (2%)
Frame = +1
Query: 2050 NVMEAPNEGQQKF--DERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKC 2223
N+ EA N Q +E+L+ SAK VA STAQL++ K + A+ D + +R+ +
Sbjct: 2405 NLCEAANAAVQGHASEEKLISSAKQVAASTAQLLVACK-VKADHDS-EAMKRLQAAGNAV 2462
Query: 2224 AFATSQLVACARVVAPTIDNN 2286
A+ LV A+ A D++
Sbjct: 2463 KRASDNLVKAAQKAAAFQDHD 2483
>gi|34864297|ref|XP_236367.2| similar to talin 2 [Rattus norvegicus]
Length = 2660
Score = 658 bits (1698), Expect = 0.0
Identities = 393/1008 (38%), Positives = 574/1008 (55%), Gaps = 16/1008 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVN-ANEYGIFRLDENPSK 177
M LSL + + KTMQFEPST +YDA ++IRE+ A++YG+F DE+P K
Sbjct: 3 MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK 62
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ GRT ++Y++RN D +EYK+K R K+RMLDG+VKT+ VD+S+ V +L++T+C++
Sbjct: 63 GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR 122
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+NYEEYSL+++ I GT+R
Sbjct: 123 IGITNYEEYSLIQETIEEKKEEGT--------------------------------GTLR 150
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L+ KLHTD++L WLDH++T REQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 151 KDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDS 210
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPK-FHLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV E A + Q+ IQ+G K K LD ++ L
Sbjct: 211 RDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFL 270
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK KYV L R L+TYGV+FF+VKEK+ GKNKL
Sbjct: 271 PKEYIKQRGAEKRIFQEHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKL 330
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ K+SVMRVDE +K++L+EWPL V+RW S K F+LDFG+YQ+ YYSVQTT+G
Sbjct: 331 VPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEG 390
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATD 1419
E+I+QLI GY+DIILKKK+++D G+EGDE STMLE+ V+P K+T++ Q A
Sbjct: 391 EQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ-QFNRTGKAEH 449
Query: 1420 GLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLR-YQDMYQHPQRALIGT 1596
G VA+ V+R+ G + S Q++ Q R + Q+AL+GT
Sbjct: 450 GSVALPAVMRSGSSGP------ETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGT 503
Query: 1597 IEATIRAVEDAEIELEAEPQID-IPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXX 1773
I ++ AV+ A+ +L ++D +P D + W++ + +K ++ ++ A+
Sbjct: 504 INTSMHAVQQAQDDLS---ELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTA 560
Query: 1774 XXXXXXXXEEYD---DRVGTAIATIGSNLPDVSRNVRDLGAFMEH--RERGDLLDATKKL 1938
+ D VG AI TI SNL ++S+ V+ L A M+ DLL A + L
Sbjct: 561 SVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDDVGSGEDLLRAARTL 620
Query: 1939 CGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKN 2118
GA L V P + R V AG +G+ S L+ + NE ++F + L+ AK
Sbjct: 621 AGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQI-GENETDERFQDVLMSLAKA 679
Query: 2119 VATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQ 2298
VA + A LVL AK ++ ++ +Q RVI +AT+CA +TSQLVACA+VV+PTI + CQ+
Sbjct: 680 VANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQE 739
Query: 2299 QLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTT 2478
QL A V +SV N + + A L + AA V+ AL LL+H +
Sbjct: 740 QLIEAGKLVDRSVENCVRACQAATGDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEP 799
Query: 2479 RREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQR--PEHRE 2652
++ + ++ T + G + ++ R+AR + + + L + +A E+ +
Sbjct: 800 IGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSK 859
Query: 2653 RLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIM 2832
+LL AA +A +T+ M+ A + A + P + + LR AAE L I+
Sbjct: 860 KLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIV 919
Query: 2833 QRLEQAAKQTAYDATQTISAANSAKKKQQEHKRTETTEQLLVDDSHTI 2976
RLE AAKQ A ATQTI+A+ +A + + +Q LV T+
Sbjct: 920 NRLEVAAKQAAAAATQTIAASQNAAIS----NKNPSAQQQLVQSCKTV 963
Score = 51.6 bits (122), Expect = 1e-04
Identities = 64/292 (21%), Positives = 113/292 (37%), Gaps = 2/292 (0%)
Frame = +1
Query: 2092 ERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAP 2271
++LVQS K VA QLV + A+ ++ Q +I S+ S++V+ A+ P
Sbjct: 954 QQLVQSCKTVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVP 1013
Query: 2272 TIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHA 2451
T+ + A QLS A + S+ L A ++ +I ++A L S L+ A
Sbjct: 1014 TVSDQAAAMQLSQCAKNLATSLAE-LRTASQKAHEACGPMEI-DSALNTVQTLKSELQDA 1071
Query: 2452 KCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKV-VRHSQLLTEQFQHEA 2628
K + + + + E L + ++DL ++ V +QLLT Q
Sbjct: 1072 KMA----AAESQLKPLPGETLEKC---------AQDLGSTSKGVGSSMAQLLTCAAQGNE 1118
Query: 2629 HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXX 2808
H A +A A + +T E+ +++ + + L
Sbjct: 1119 HYTGVAARETAQALKTLAQAARGVAASTNDPEAAHAMLDSARDVMEGSAMLIQEAKQALI 1178
Query: 2809 XXXXXHIMQRLEQAAKQTAYDATQTISAANSAKKKQQEHKRT-ETTEQLLVD 2961
QRL Q AK ++ ++ K K E++++LLVD
Sbjct: 1179 APGDTESQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVD 1230
>gi|22035665|ref|NP_055874.1| talin 2 [Homo sapiens]
gi|26400725|sp|Q9Y4G6|TLN2_HUMAN Talin 2
Length = 2542
Score = 658 bits (1697), Expect = 0.0
Identities = 388/984 (39%), Positives = 566/984 (57%), Gaps = 16/984 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVN-ANEYGIFRLDENPSK 177
M LSL + + KTMQFEPST +YDA ++IRE+ A++YG+F DE+P K
Sbjct: 1 MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK 60
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ GRT ++Y++RN D +EYK+K R K+RMLDG+VKT+ VD+S+ V +L++T+C++
Sbjct: 61 GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR 120
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+NYEEYSL+++ I GT++
Sbjct: 121 IGITNYEEYSLIQETIEEKKEEGT--------------------------------GTLK 148
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L+ KLHTD++L WLDH++T REQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 149 KDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDS 208
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPK-FHLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV E A + Q+ IQ+G K K LD ++ L
Sbjct: 209 RDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFL 268
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK KYV L R L+TYGV+FF+VKEK+ GKNKL
Sbjct: 269 PKEYIKQRGAEKRIFQAHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKL 328
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ K+SVMRVDE +K++L+EWPL V+RW S K F+LDFG+YQ+ YYSVQTT+G
Sbjct: 329 VPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEG 388
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATD 1419
E+I+QLI GY+DIILKKK+++D G+EGDE STMLE+ V+P K+T++ Q A
Sbjct: 389 EQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ-QFNRTGKAEH 447
Query: 1420 GLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLR-YQDMYQHPQRALIGT 1596
G VA+ V+R+ G + S Q++ Q R + Q+AL+GT
Sbjct: 448 GSVALPAVMRSGSSGP------ETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGT 501
Query: 1597 IEATIRAVEDAEIELEAEPQID-IPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXX 1773
I ++ AV+ A+ +L ++D +P D + W++ + +K ++ ++ A+
Sbjct: 502 INTSMHAVQQAQDDLS---ELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTA 558
Query: 1774 XXXXXXXXEEYD---DRVGTAIATIGSNLPDVSRNVRDLGAFMEHR--ERGDLLDATKKL 1938
+ D VG AI TI SNL ++S+ V+ L A M+ DLL A + L
Sbjct: 559 SVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDEVGSGEDLLRAARTL 618
Query: 1939 CGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKN 2118
GA L V P + R V AG +G+ S L+ + NE ++F + L+ AK
Sbjct: 619 AGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQI-GENETDERFQDVLMSLAKA 677
Query: 2119 VATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQ 2298
VA + A LVL AK ++ ++ +Q RVI +AT+CA +TSQLVACA+VV+PTI + CQ+
Sbjct: 678 VANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQE 737
Query: 2299 QLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTT 2478
QL A V +SV N + + A L + AA V+ AL LL+H +
Sbjct: 738 QLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEP 797
Query: 2479 RREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQR--PEHRE 2652
++ + ++ T + G + ++ R+AR + + + L + +A E+ +
Sbjct: 798 IGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSK 857
Query: 2653 RLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIM 2832
+LL AA +A +T+ M+ A + A + P + + LR AAE L I+
Sbjct: 858 KLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIV 917
Query: 2833 QRLEQAAKQTAYDATQTISAANSA 2904
RLE AAKQ A ATQTI+A+ +A
Sbjct: 918 NRLEVAAKQAAAAATQTIAASQNA 941
Score = 48.1 bits (113), Expect = 0.001
Identities = 64/296 (21%), Positives = 115/296 (38%), Gaps = 6/296 (2%)
Frame = +1
Query: 2092 ERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAP 2271
++LVQS K VA QLV + A+ ++ Q +I S+ S++V+ A+ P
Sbjct: 952 QQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVP 1011
Query: 2272 TIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAA--RQVTSALDSL-- 2439
T+ + A QLS A + S+ L ++ A HEA ++ SAL+++
Sbjct: 1012 TVSDQAAAMQLSQCAKNLATSLAELRTASQKA----------HEACGPMEIDSALNTVQT 1061
Query: 2440 LEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKV-VRHSQLLTEQF 2616
L++ K + + + E L + ++DL ++ V +QLLT
Sbjct: 1062 LKNELQDAKMAAVESQLKPLPGETLEKC---------AQDLGSTSKAVGSSMAQLLTCAA 1112
Query: 2617 QHEAHQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXX 2796
Q H A +A A + +T + +++ + + L
Sbjct: 1113 QGNEHYTGVAARETAQALKTLAQAARGVAASTTDPAAAHAMLDSARDVMEGSAMLIQEAK 1172
Query: 2797 XXXXXXXXXHIMQRLEQAAKQTAYDATQTISAANSAKKKQQEHKRT-ETTEQLLVD 2961
QRL Q AK ++ ++ K K E++++LLVD
Sbjct: 1173 QALIAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVD 1228
>gi|21666571|gb|AAM73764.1| talin 2 [Homo sapiens]
Length = 2542
Score = 658 bits (1697), Expect = 0.0
Identities = 388/984 (39%), Positives = 566/984 (57%), Gaps = 16/984 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVN-ANEYGIFRLDENPSK 177
M LSL + + KTMQFEPST +YDA ++IRE+ A++YG+F DE+P K
Sbjct: 1 MVALSLKICVRHCNVVKTMQFEPSTAVYDACRVIRERVPEAQTGQASDYGLFLSDEDPRK 60
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ GRT ++Y++RN D +EYK+K R K+RMLDG+VKT+ VD+S+ V +L++T+C++
Sbjct: 61 GIWLEAGRTLDYYMLRNGDILEYKKKQRPQKIRMLDGSVKTVMVDDSKTVGELLVTICSR 120
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+NYEEYSL+++ I GT++
Sbjct: 121 IGITNYEEYSLIQETIEEKKEEGT--------------------------------GTLK 148
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L+ KLHTD++L WLDH++T REQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 149 KDRTLLRDERKMEKLKAKLHTDDDLNWLDHSRTFREQGVDENETLLLRRKFFYSDQNVDS 208
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPK-FHLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV E A + Q+ IQ+G K K LD ++ L
Sbjct: 209 RDPVQLNLLYVQARDDILNGSHPVSFEKACEFGGFQAQIQFGPHVEHKHKPGFLDLKEFL 268
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK KYV L R L+TYGV+FF+VKEK+ GKNKL
Sbjct: 269 PKEYIKQRGAEKRIFQAHKNCGEMSEIEAKVKYVKLARSLRTYGVSFFLVKEKMKGKNKL 328
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ K+SVMRVDE +K++L+EWPL V+RW S K F+LDFG+YQ+ YYSVQTT+G
Sbjct: 329 VPRLLGITKDSVMRVDEKTKEVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEG 388
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLVAHGQIGSGQHATD 1419
E+I+QLI GY+DIILKKK+++D G+EGDE STMLE+ V+P K+T++ Q A
Sbjct: 389 EQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQ-QFNRTGKAEH 447
Query: 1420 GLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLR-YQDMYQHPQRALIGT 1596
G VA+ V+R+ G + S Q++ Q R + Q+AL+GT
Sbjct: 448 GSVALPAVMRSGSSGP------ETFNVGSMPSPQQQVMVGQMHRGHMPPLTSAQQALMGT 501
Query: 1597 IEATIRAVEDAEIELEAEPQID-IPRFNDDYSQNRWMEEQQAVNKENVNERLAAMGXXXX 1773
I ++ AV+ A+ +L ++D +P D + W++ + +K ++ ++ A+
Sbjct: 502 INTSMHAVQQAQDDLS---ELDSLPPLGQDMASRVWVQNKVDESKHEIHSQVDAITAGTA 558
Query: 1774 XXXXXXXXEEYD---DRVGTAIATIGSNLPDVSRNVRDLGAFMEHR--ERGDLLDATKKL 1938
+ D VG AI TI SNL ++S+ V+ L A M+ DLL A + L
Sbjct: 559 SVVNLTAGDPADTDYTAVGCAITTISSNLTEMSKGVKLLAALMDDEVGSGEDLLRAARTL 618
Query: 1939 CGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAKN 2118
GA L V P + R V AG +G+ S L+ + NE ++F + L+ AK
Sbjct: 619 AGAVSDLLKAVQPTSGEPRQTVLTAAGSIGQASGDLLRQI-GENETDERFQDVLMSLAKA 677
Query: 2119 VATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQQ 2298
VA + A LVL AK ++ ++ +Q RVI +AT+CA +TSQLVACA+VV+PTI + CQ+
Sbjct: 678 VANAAAMLVLKAKNVAQVAEDTVLQNRVIAAATQCALSTSQLVACAKVVSPTISSPVCQE 737
Query: 2299 QLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQTT 2478
QL A V +SV N + + A L + AA V+ AL LL+H +
Sbjct: 738 QLIEAGKLVDRSVENCVRACQAATTDSELLKQVSAAASVVSQALHDLLQHVRQFASRGEP 797
Query: 2479 RREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQR--PEHRE 2652
++ + ++ T + G + ++ R+AR + + + L + +A E+ +
Sbjct: 798 IGRYDQATDTIMCVTESIFSSMGDAGEMVRQARVLAQATSDLVNAMRSDAEAEIDMENSK 857
Query: 2653 RLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHIM 2832
+LL AA +A +T+ M+ A + A + P + + LR AAE L I+
Sbjct: 858 KLLAAAKLLADSTARMVEAAKGAAANPENEDQQQRLREAAEGLRVATNAAAQNAIKKKIV 917
Query: 2833 QRLEQAAKQTAYDATQTISAANSA 2904
RLE AAKQ A ATQTI+A+ +A
Sbjct: 918 NRLEVAAKQAAAAATQTIAASQNA 941
Score = 48.1 bits (113), Expect = 0.001
Identities = 64/296 (21%), Positives = 115/296 (38%), Gaps = 6/296 (2%)
Frame = +1
Query: 2092 ERLVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAP 2271
++LVQS K VA QLV + A+ ++ Q +I S+ S++V+ A+ P
Sbjct: 952 QQLVQSCKAVADHIPQLVQGVRGSQAQAEDLSAQLALIISSQNFLQPGSKMVSSAKAAVP 1011
Query: 2272 TIDNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAA--RQVTSALDSL-- 2439
T+ + A QLS A + S+ L ++ A HEA ++ SAL+++
Sbjct: 1012 TVSDQAAAMQLSQCAKNLATSLAELRTASQKA----------HEACGPMEIDSALNTVQT 1061
Query: 2440 LEHAKCSPKTQTTRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKV-VRHSQLLTEQF 2616
L++ K + + + E L + ++DL ++ V +QLLT
Sbjct: 1062 LKNELQDAKMAAVESQLKPLPGETLEKC---------AQDLGSTSKAVGSSMAQLLTCAA 1112
Query: 2617 QHEAHQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXX 2796
Q H A +A A + +T + +++ + + L
Sbjct: 1113 QGNEHYTGVAARETAQALKTLAQAARGVAASTTDPAAAHAMLDSARDVMEGSAMLIQEAK 1172
Query: 2797 XXXXXXXXXHIMQRLEQAAKQTAYDATQTISAANSAKKKQQEHKRT-ETTEQLLVD 2961
QRL Q AK ++ ++ K K E++++LLVD
Sbjct: 1173 QALIAPGDAERQQRLAQVAKAVSHSLNNCVNCLPGQKDVDVALKSIGESSKKLLVD 1228
>gi|34867875|ref|XP_242982.2| similar to talin [Rattus norvegicus]
Length = 2539
Score = 655 bits (1690), Expect = 0.0
Identities = 397/985 (40%), Positives = 577/985 (58%), Gaps = 17/985 (1%)
Frame = +1
Query: 1 MGVLSLTVSSAEKGIKKTMQFEPSTLIYDAAKLIREKFAMHDVNA-NEYGIFRLDENPSK 177
M LSL +S + KTMQFEPST++YDA ++IRE+ +++G+F D++P K
Sbjct: 1 MVALSLRISIGN--VVKTMQFEPSTMVYDACRMIRERIPEALAGPPSDFGLFLSDDDPKK 58
Query: 178 SLWMDNGRTFEHYLVRNKDEIEYKRKIRLLKVRMLDGAVKTISVDESQPVSQLMMTVCNK 357
+W++ G+ ++Y++RN D +EY++K R LK+RMLDG VKTI VD+S+ V+ ++MT+C +
Sbjct: 59 GIWLEAGKALDYYMLRNGDTMEYRKKQRPLKIRMLDGTVKTIMVDDSKTVTDMLMTICAR 118
Query: 358 IGISNYEEYSLVRDDILMXXXXXXXXXXXXXXXSTWNLXXXXXXXXXXXXXXXXIYGTMR 537
IGI+N++EYSLVR+ LM GT+R
Sbjct: 119 IGITNHDEYSLVRE--LMEEKKDEGT------------------------------GTLR 146
Query: 538 K-----KNEQKLEELRKKLHTDEELPWLDHTKTLREQGITEEETLILRRKYFFSDSNVDS 702
K ++E+K+E+L++KLHTD+EL WLDH +TLREQG+ E ETL+LRRK+F+SD NVDS
Sbjct: 147 KDKTLLRDEKKMEKLKQKLHTDDELNWLDHGRTLREQGVEEHETLLLRRKFFYSDQNVDS 206
Query: 703 RDPVQLNLLYVQCRDGILRGLHPVEKETAFQLAALQSHIQYGDFPYDKPKF-HLDGRDVL 879
RDPVQLNLLYVQ RD IL G HPV + A + A Q IQ+G K K LD +D L
Sbjct: 207 RDPVQLNLLYVQARDDILNGSHPVSFDKACEFAGFQCQIQFGPHNEQKHKAGFLDLKDFL 266
Query: 880 PKEYXXXXXXXXXXXXMYKELSGTSELDAKSKYVHLCRGLKTYGVTFFVVKEKLPGKNKL 1059
PKEY +K SE++AK +YV L R LKTYGV+FF+VKEK+ GKNKL
Sbjct: 267 PKEYVKQKGERKIFQA-HKNCGQMSEIEAKVRYVKLARSLKTYGVSFFLVKEKMKGKNKL 325
Query: 1060 VPRLLGVNKESVMRVDENSKQILKEWPLEQVRRWVPSAKCFSLDFGDYQDGYYSVQTTDG 1239
VPRLLG+ KE VMRVDE +K++++EW L ++RW S K F+LDFGDYQDGYYSVQTT+G
Sbjct: 326 VPRLLGITKECVMRVDEKTKEVIQEWSLTNIKRWAASPKSFTLDFGDYQDGYYSVQTTEG 385
Query: 1240 EKIAQLIQGYVDIILKKKRTQDHQGIEGDEGSTMLEDMVAPAKATLV--AHGQIGSGQHA 1413
E+IAQLI GY+DIILKKK+++DH G+EGDE STMLED V+P K+T++ + ++G +H
Sbjct: 386 EQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSVSPKKSTVLQQQYNRVGKAEH- 444
Query: 1414 TDGLVAVRGVLRTPQGGQGYGINGAQYGAVSGEITSQELARAQRLRYQDMYQHPQRALIG 1593
G VA+ ++R+ G G+ A ++TS ++ R + Q+AL G
Sbjct: 445 --GSVALPAIMRSGASGPENFQVGSMPPA-QQQVTSGQMHRG----HMPPLTSAQQALTG 497
Query: 1594 TIEATIRAVEDAEIELEAEPQIDIPRFNDDYSQNRWMEEQQAVNKENVNERLAAM--GXX 1767
TI ++++AV+ A+ L+ +P D W + + +K ++ ++ A+ G
Sbjct: 498 TINSSMQAVQAAQAALDDFDA--LPPLGQD--AVTWRKNKMDESKHEIHSQVDAITAGTA 553
Query: 1768 XXXXXXXXXXEEYD-DRVGTAIATIGSNLPDVSRNVRDLGAFMEHRERGD---LLDATKK 1935
E D VG A+ TI SNL ++SR V+ L A +E E G+ LL A K
Sbjct: 554 SVVNLTAGDPAETDYTAVGCAVTTISSNLTEMSRGVKLLAALLED-EGGNGRPLLQAAKG 612
Query: 1936 LCGAFGKFLNTVNPETEARRNEVFRTAGHVGETSQHLINVMEAPNEGQQKFDERLVQSAK 2115
L GA + L + P + R + + AG+VG+ S L+ + ++ F + L+Q AK
Sbjct: 613 LAGAVSELLRSAQPASAEPRQNLLQAAGNVGQASGELLQQI-GESDTDPHFQDILMQLAK 671
Query: 2116 NVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTIDNNACQ 2295
VA++ A LVL AK+++ ++ +Q +VI +AT+CA +TSQLVAC +VVAPTI + CQ
Sbjct: 672 AVASAAAALVLKAKSVAQRTEDSGLQTQVIAAATQCALSTSQLVACTKVVAPTISSPVCQ 731
Query: 2296 QQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKCSPKTQT 2475
+QL A V ++V + ++ A L + AA VT AL+ LL+H K
Sbjct: 732 EQLVEAGRLVAKAVEGCVSASQAATEDGQLLRGVGAAATAVTQALNELLQHVKAHATGAG 791
Query: 2476 TRREEEEMYNEVLRRTNRMVVHQGPSEDLTREARKVVRHSQLLTEQFQHEAHQRP--EHR 2649
++ + +L T + G + ++ R+AR + + + L + +A E+
Sbjct: 792 PAGRYDQATDTILTVTENIFSSMGDAGEMVRQARILAQATSDLVNAIKADAEGESDLENS 851
Query: 2650 ERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAAERLGXXXXXXXXXXXXXHI 2829
+LL AA +A AT++M+ A + A + P E + LR AAE L +
Sbjct: 852 RKLLSAAKILADATAKMVEAAKGAAAHPDSEEQQQRLREAAEGLRMATNAAAQNAIKKKL 911
Query: 2830 MQRLEQAAKQTAYDATQTISAANSA 2904
+QRLE AAKQ A ATQTI+AA A
Sbjct: 912 VQRLEHAAKQAAASATQTIAAAQHA 936
Score = 41.6 bits (96), Expect = 0.11
Identities = 57/241 (23%), Positives = 94/241 (38%), Gaps = 15/241 (6%)
Frame = +1
Query: 2098 LVQSAKNVATSTAQLVLCAKTISAECDEPQVQERVIQSATKCAFATSQLVACARVVAPTI 2277
LVQS K VA LV + A+ D P Q +I ++ ++VA A+ PTI
Sbjct: 950 LVQSCKAVAEQIPLLVQGVRGSQAQPDSPSAQLALIAASQSFLQPGGKMVAAAKASVPTI 1009
Query: 2278 DNNACQQQLSTAATEVTQSVNNLLHDAEHAVYQQSSLTDIHEAARQVTSALDSLLEHAKC 2457
+ A QLS A + ++ L A+ A Q++ ++A V L+ L+ K
Sbjct: 1010 QDQASAMQLSQCAKNLGTALAELRTAAQKA--QEACGPLEMDSALSVVQNLEKDLQEIKA 1067
Query: 2458 SP---KTQTTRREEEEMYNEVLRRTNRMV----------VHQGPSEDLTREARKVVRHSQ 2598
+ K + E E + L + + V + QG AR V +
Sbjct: 1068 AAREGKLKPLPGETMEKCTQDLGNSTKAVSSAIAKLLGEIAQGNENYAGIAARDVAGGLR 1127
Query: 2599 LLTEQFQHEA--HQRPEHRERLLDAAAKVAHATSEMILATEQAESQPRQVETEYALRTAA 2772
L + + A P + +LD A+ S +I ++A P E++ L A
Sbjct: 1128 SLAQAARGVAALTTDPAVQAIVLDTASDALDKASSLIEEAKKASGHPGDPESQQRLAQVA 1187
Query: 2773 E 2775
+
Sbjct: 1188 K 1188