Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= Y56A3A_24
(2280 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17555378|ref|NP_499558.1| TOPoisomerase (85.4 kD) (top-3) [Ca... 1360 0.0
gi|39584856|emb|CAE67751.1| Hypothetical protein CBG13326 [Caeno... 1202 0.0
gi|49115195|gb|AAH73221.1| Unknown (protein for MGC:80537) [Xeno... 635 e-180
gi|1292913|gb|AAB03695.1| DNA topoisomerase III 632 e-179
gi|10835218|ref|NP_004609.1| topoisomerase (DNA) III alpha; topo... 632 e-179
gi|6678403|ref|NP_033436.1| topoisomerase (DNA) III alpha; topoi... 627 e-178
gi|24585251|ref|NP_523602.2| CG10123-PA [Drosophila melanogaster... 600 e-170
gi|7960302|gb|AAF71288.1| DNA topoisomerase III alpha [Drosophil... 600 e-170
gi|26325928|dbj|BAC26718.1| unnamed protein product [Mus musculus] 550 e-155
gi|50755615|ref|XP_414821.1| PREDICTED: similar to topoisomerase... 523 e-147
gi|46124677|ref|XP_386892.1| hypothetical protein FG06716.1 [Gib... 521 e-146
gi|49094462|ref|XP_408692.1| hypothetical protein AN4555.2 [Aspe... 518 e-145
gi|49072148|ref|XP_400363.1| hypothetical protein UM02748.1 [Ust... 497 e-139
gi|50255655|gb|EAL18388.1| hypothetical protein CNBJ3110 [Crypto... 486 e-136
gi|15237561|ref|NP_201197.1| DNA topoisomerase III alpha, putati... 481 e-134
gi|47211975|emb|CAF95297.1| unnamed protein product [Tetraodon n... 479 e-133
gi|19569875|gb|AAL92194.1| similar to DNA Topoisomerase III; Top... 478 e-133
gi|19113553|ref|NP_596761.1| dna topoisomerase iii [Schizosaccha... 475 e-132
gi|50427029|ref|XP_462119.1| unnamed protein product [Debaryomyc... 466 e-130
gi|45200996|ref|NP_986566.1| AGL101Cp [Eremothecium gossypii] >g... 460 e-128
gi|46445011|gb|EAL04282.1| hypothetical protein CaO19.13355 [Can... 454 e-126
gi|32403108|ref|XP_322167.1| hypothetical protein [Neurospora cr... 448 e-124
gi|48098355|ref|XP_394050.1| similar to topoisomerase (DNA) III ... 425 e-117
gi|50288605|ref|XP_446732.1| unnamed protein product [Candida gl... 422 e-116
gi|6323263|ref|NP_013335.1| DNA Topoisomerase III; Top3p [Saccha... 421 e-116
gi|34871530|ref|XP_220527.2| similar to topoisomerase III [Rattu... 412 e-113
gi|50311957|ref|XP_456010.1| unnamed protein product [Kluyveromy... 405 e-111
gi|50556688|ref|XP_505752.1| hypothetical protein [Yarrowia lipo... 398 e-109
gi|28422192|gb|AAH46848.1| MGC53016 protein [Xenopus laevis] 383 e-104
gi|42569543|ref|NP_180760.2| DNA topoisomerase family protein [A... 382 e-104
gi|31209141|ref|XP_313537.1| ENSANGP00000018921 [Anopheles gambi... 377 e-103
gi|6755851|ref|NP_035754.1| topoisomerase (DNA) III beta; Topo I... 373 e-102
gi|4507635|ref|NP_003926.1| topoisomerase (DNA) III beta; topois... 371 e-101
gi|12803239|gb|AAH02432.1| Topoisomerase (DNA) III beta [Homo sa... 369 e-100
gi|50756221|ref|XP_415066.1| PREDICTED: similar to topoisomerase... 368 e-100
gi|19074185|ref|NP_584791.1| DNA TOPOISOMERASE III [Encephalitoz... 366 1e-99
gi|34902572|ref|NP_912632.1| Putative DNA topoisomerase III [Ory... 361 4e-98
gi|31235063|ref|XP_319175.1| ENSANGP00000011926 [Anopheles gambi... 359 2e-97
gi|4235475|gb|AAD13219.1| topoisomerase III [Drosophila melanoga... 357 5e-97
gi|24640096|ref|NP_511059.2| CG3458-PA [Drosophila melanogaster]... 357 5e-97
gi|34869837|ref|XP_213564.2| similar to topoisomerase III beta [... 342 2e-92
gi|32398820|emb|CAD98530.1| DNA topoisomerase III beta-1, probab... 342 2e-92
gi|32563869|ref|NP_496822.2| TOPRIM and DNA topoisomerase I (2N6... 334 6e-90
gi|39591301|emb|CAE73354.1| Hypothetical protein CBG20786 [Caeno... 333 1e-89
gi|7510001|pir||T31599 hypothetical protein Y48C3A.q - Caenorhab... 323 8e-87
gi|2114264|dbj|BAA20009.1| topoisomerase-III [Homo sapiens] 313 9e-84
gi|48101757|ref|XP_395206.1| similar to ENSANGP00000006676 [Apis... 302 2e-80
gi|27882184|gb|AAH43953.1| MGC53016 protein [Xenopus laevis] 301 6e-80
gi|8918930|dbj|BAA97984.1| unnamed protein product [Mus musculus] 290 1e-76
gi|23485425|gb|EAA20423.1| DNA topoisomerase iii [Plasmodium yoe... 283 2e-74
gi|20090640|ref|NP_616715.1| DNA topoisomerase, type I [Methanos... 282 3e-74
gi|48839180|ref|ZP_00296114.1| COG0550: Topoisomerase IA [Methan... 281 4e-74
gi|21226285|ref|NP_632207.1| DNA topoisomerase III [Methanosarci... 281 5e-74
gi|46142693|ref|ZP_00149453.2| COG0550: Topoisomerase IA [Methan... 277 9e-73
gi|18313747|ref|NP_560414.1| DNA topoisomerase (topA) [Pyrobacul... 277 9e-73
gi|23619395|ref|NP_705357.1| DNA topoisomerase III, putative [Pl... 273 1e-71
gi|25408202|pir||G84727 probable DNA topoisomerase III beta [imp... 271 5e-71
gi|29248890|gb|EAA40413.1| GLP_43_17393_20314 [Giardia lamblia A... 261 5e-68
gi|20091341|ref|NP_617416.1| DNA topoisomerase, type I [Methanos... 255 3e-66
gi|21229178|ref|NP_635100.1| DNA topoisomerase I [Methanosarcina... 246 2e-63
gi|48838406|ref|ZP_00295350.1| COG0550: Topoisomerase IA [Methan... 244 7e-63
gi|41719184|ref|ZP_00148098.1| COG0550: Topoisomerase IA [Methan... 243 1e-62
gi|11499394|ref|NP_070633.1| DNA topoisomerase I (topA) [Archaeo... 242 3e-62
gi|16554466|ref|NP_444190.1| DNA topoisomerase I [Halobacterium ... 242 3e-62
gi|13540850|ref|NP_110538.1| DNA topoisomerase IA [Thermoplasma ... 241 6e-62
gi|46105814|ref|ZP_00186167.2| COG0550: Topoisomerase IA [Rubrob... 228 4e-58
gi|48477819|ref|YP_023525.1| DNA topoisomerase I [Picrophilus to... 223 1e-56
gi|16081238|ref|NP_393542.1| DNA topoisomerase III beta related ... 220 1e-55
gi|15669848|ref|NP_248662.1| DNA topoisomerase I [Methanocaldoco... 205 4e-51
gi|14521628|ref|NP_127104.1| DNA topoisomerase I [Pyrococcus aby... 195 5e-48
gi|45358519|ref|NP_988076.1| DNA topoisomerase I [Methanococcus ... 194 8e-48
gi|14590513|ref|NP_142581.1| DNA topoisomerase I [Pyrococcus hor... 193 2e-47
gi|48852330|ref|ZP_00306518.1| COG0550: Topoisomerase IA [Ferrop... 191 7e-47
gi|15679619|ref|NP_276736.1| DNA topoisomerase I [Methanothermob... 189 3e-46
gi|25409341|pir||B84194 DNA topoisomerase I [imported] - Halobac... 172 4e-41
gi|14601630|ref|NP_148170.1| DNA topoisomerase [Aeropyrum pernix... 166 2e-39
gi|42781053|ref|NP_978300.1| DNA topoisomerase III [Bacillus cer... 162 3e-38
gi|21399784|ref|NP_655769.1| Topoisom_bac, DNA topoisomerase [Ba... 161 7e-38
gi|49481155|ref|YP_036076.1| DNA topoisomerase I [Bacillus thuri... 160 9e-38
gi|30019974|ref|NP_831605.1| DNA topoisomerase I [Bacillus cereu... 160 1e-37
gi|14423990|sp|Q9X3X7|TOP1_ZYMMO DNA topoisomerase I (Omega-prot... 151 7e-35
gi|29248910|gb|EAA40433.1| GLP_43_51656_54346 [Giardia lamblia A... 148 6e-34
gi|15615949|ref|NP_244253.1| DNA topoisomerase III [Bacillus hal... 147 8e-34
gi|23114967|ref|ZP_00100244.1| COG0550: Topoisomerase IA [Desulf... 146 2e-33
gi|47206372|emb|CAF93528.1| unnamed protein product [Tetraodon n... 146 2e-33
gi|46113460|ref|ZP_00182895.2| COG0550: Topoisomerase IA [Exiguo... 143 2e-32
gi|18310490|ref|NP_562424.1| DNA topoisomerase III [Clostridium ... 143 2e-32
gi|15604194|ref|NP_220709.1| DNA TOPOISOMERASE I (topA) [Rickett... 141 8e-32
gi|39997644|ref|NP_953595.1| DNA topoisomerase I [Geobacter sulf... 140 1e-31
gi|28493663|ref|NP_787824.1| DNA topoisomerase I [Tropheryma whi... 140 2e-31
gi|28572856|ref|NP_789636.1| DNA topoisomerase I [Tropheryma whi... 140 2e-31
gi|49237021|ref|ZP_00331076.1| COG0550: Topoisomerase IA [Moorel... 139 4e-31
gi|15792989|ref|NP_282812.1| DNA topoisomerase I [Campylobacter ... 139 4e-31
gi|48846768|ref|ZP_00301027.1| COG0550: Topoisomerase IA [Geobac... 138 5e-31
gi|15615030|ref|NP_243333.1| DNA topoisomerase I [Bacillus halod... 138 5e-31
gi|15643028|ref|NP_228071.1| DNA topoisomerase [Thermotoga marit... 138 5e-31
gi|16760166|ref|NP_455783.1| DNA topoisomerase I, omega protein ... 137 9e-31
gi|46120624|ref|ZP_00171807.2| COG0550: Topoisomerase IA [Methyl... 136 2e-30
gi|23099001|ref|NP_692467.1| DNA topoisomerase I [Oceanobacillus... 136 2e-30
gi|7245299|pdb|1CY1|A Chain A, Complex Of E.Coli Dna Topoisomera... 135 4e-30
gi|26988863|ref|NP_744288.1| DNA topoisomerase I [Pseudomonas pu... 135 4e-30
gi|16129235|ref|NP_415790.1| DNA topoisomerase type I, omega pro... 135 4e-30
gi|18310684|ref|NP_562618.1| DNA topoisomerase I [Clostridium pe... 135 6e-30
gi|26247605|ref|NP_753645.1| DNA topoisomerase I [Escherichia co... 135 6e-30
gi|1127274|pdb|1ECL| Amino Terminal 67kda Domain Of Escherichia... 135 6e-30
gi|42557740|emb|CAF28714.1| putative DNA topoisomerase I [uncult... 135 6e-30
gi|30062796|ref|NP_836967.1| DNA topoisomerase type I, omega pro... 135 6e-30
gi|15801905|ref|NP_287925.1| DNA topoisomerase type I, omega pro... 135 6e-30
gi|38232948|ref|NP_938715.1| DNA topoisomerase I [Corynebacteriu... 134 7e-30
gi|23100045|ref|NP_693511.1| DNA topoisomerase III [Oceanobacill... 134 9e-30
gi|15598207|ref|NP_251701.1| DNA topoisomerase I [Pseudomonas ae... 134 9e-30
gi|23103218|ref|ZP_00089705.1| COG0550: Topoisomerase IA [Azotob... 133 2e-29
gi|20095040|ref|NP_614887.1| Topoisomerase IA [Methanopyrus kand... 133 2e-29
gi|34580624|ref|ZP_00142104.1| DNA topoisomerase I [Rickettsia s... 133 2e-29
gi|32028922|ref|ZP_00132025.1| COG0550: Topoisomerase IA [Haemop... 132 3e-29
gi|13470988|ref|NP_102557.1| DNA topoisomerase I [Mesorhizobium ... 132 3e-29
gi|46129865|ref|ZP_00164495.2| COG0550: Topoisomerase IA [Synech... 132 4e-29
gi|47212929|emb|CAF90301.1| unnamed protein product [Tetraodon n... 132 4e-29
gi|50121214|ref|YP_050381.1| DNA topoisomerase I [Erwinia caroto... 132 4e-29
gi|33152456|ref|NP_873809.1| DNA topoisomerase I [Haemophilus du... 132 4e-29
gi|38492440|pdb|1MW8|X Chain X, Crystal Structure Of A Complex B... 132 4e-29
gi|48859233|ref|ZP_00313170.1| COG0550: Topoisomerase IA [Clostr... 132 5e-29
gi|28870675|ref|NP_793294.1| DNA topoisomerase I [Pseudomonas sy... 131 6e-29
gi|28210156|ref|NP_781100.1| DNA topoisomerase I [Clostridium te... 131 6e-29
gi|34540543|ref|NP_905022.1| DNA topoisomerase I [Porphyromonas ... 131 6e-29
gi|23467279|ref|ZP_00122862.1| COG0550: Topoisomerase IA [Haemop... 131 6e-29
gi|23472236|ref|ZP_00127563.1| COG0550: Topoisomerase IA [Pseudo... 131 8e-29
gi|15892372|ref|NP_360086.1| DNA topoisomerase I [EC:5.99.1.2] [... 131 8e-29
gi|15673212|ref|NP_267386.1| DNA topoisomerase I [Lactococcus la... 131 8e-29
gi|19551559|ref|NP_599561.1| topoisomerase IA [Corynebacterium g... 131 8e-29
gi|22537165|ref|NP_688016.1| DNA topoisomerase I [Streptococcus ... 130 1e-28
gi|25011094|ref|NP_735489.1| Unknown [Streptococcus agalactiae N... 130 2e-28
gi|15895061|ref|NP_348410.1| Topoisomerase I [Clostridium acetob... 129 2e-28
gi|20807896|ref|NP_623067.1| Topoisomerase IA [Thermoanaerobacte... 129 2e-28
gi|15793183|ref|NP_283005.1| DNA topoisomerase I [Neisseria meni... 129 2e-28
gi|24112671|ref|NP_707181.1| DNA topoisomerase type I, omega pro... 129 2e-28
gi|25026863|ref|NP_736917.1| putative DNA topoisomerase I [Coryn... 129 3e-28
gi|48730034|ref|ZP_00263783.1| COG0550: Topoisomerase IA [Pseudo... 129 3e-28
gi|15921479|ref|NP_377148.1| 664aa long hypothetical DNA topoiso... 129 3e-28
gi|50083732|ref|YP_045242.1| DNA topoisomerase type I, omega pro... 129 4e-28
gi|48766242|ref|ZP_00270792.1| COG0550: Topoisomerase IA [Rhodos... 128 5e-28
gi|15676046|ref|NP_273176.1| DNA topoisomerase I [Neisseria meni... 128 5e-28
gi|16122447|ref|NP_405760.1| DNA topoisomerase I [Yersinia pesti... 128 7e-28
gi|48854127|ref|ZP_00308291.1| COG0550: Topoisomerase IA [Cytoph... 127 9e-28
gi|25010460|ref|NP_734855.1| unknown [Streptococcus agalactiae N... 127 1e-27
gi|29376573|ref|NP_815727.1| DNA topoisomerase III [Enterococcus... 127 2e-27
gi|34499724|ref|NP_903939.1| DNA topoisomerase [Chromobacterium ... 127 2e-27
gi|21221962|ref|NP_627741.1| probable DNA topoisomerase I [Strep... 127 2e-27
gi|16126690|ref|NP_421254.1| DNA topoisomerase I [Caulobacter cr... 126 2e-27
gi|49475581|ref|YP_033622.1| DNA topoisomerase I [Bartonella hen... 126 2e-27
gi|16804793|ref|NP_466278.1| similar to DNA topoisomerase ... 126 2e-27
gi|47095564|ref|ZP_00233172.1| DNA topoisomerase III [Listeria m... 126 2e-27
gi|27468400|ref|NP_765037.1| DNA topoisomerase III topB [Staphyl... 125 3e-27
gi|28210945|ref|NP_781889.1| DNA topoisomerase I [Clostridium te... 125 3e-27
gi|23002434|ref|ZP_00046110.1| COG0550: Topoisomerase IA [Lactob... 125 3e-27
gi|15606076|ref|NP_213453.1| topoisomerase I [Aquifex aeolicus V... 125 4e-27
gi|16273275|ref|NP_439516.1| DNA topoisomerase I [Haemophilus in... 125 6e-27
gi|24379442|ref|NP_721397.1| putative DNA topoisomerase I [Strep... 125 6e-27
gi|34849373|gb|AAP58872.1| DNA topoisomerase IA [Spiroplasma kun... 125 6e-27
gi|46133437|ref|ZP_00157201.2| COG0550: Topoisomerase IA [Haemop... 124 8e-27
gi|41406523|ref|NP_959359.1| TopA [Mycobacterium avium subsp. pa... 124 8e-27
gi|33866404|ref|NP_897963.1| Prokaryotic DNA topoisomerase [Syne... 124 1e-26
gi|29655283|ref|NP_820975.1| DNA topoisomerase I [Coxiella burne... 124 1e-26
gi|34763133|ref|ZP_00144102.1| DNA topoisomerase I [Fusobacteriu... 124 1e-26
gi|33863620|ref|NP_895180.1| Prokaryotic DNA topoisomerase [Proc... 124 1e-26
gi|1174735|sp|P43012|TOP1_HAEIN DNA topoisomerase I (Omega-prote... 124 1e-26
gi|48849437|ref|ZP_00303680.1| COG0550: Topoisomerase IA [Novosp... 124 1e-26
gi|15901123|ref|NP_345727.1| DNA topoisomerase I [Streptococcus ... 124 1e-26
gi|21233183|ref|NP_639100.1| DNA topoisomerase I [Xanthomonas ca... 124 1e-26
gi|15903184|ref|NP_358734.1| DNA topoisomerase I [Streptococcus ... 124 1e-26
gi|49474247|ref|YP_032289.1| DNA topoisomerase I [Bartonella qui... 123 2e-26
gi|15924240|ref|NP_371774.1| DNA topoisomerase I topA homologue ... 123 2e-26
gi|21282862|ref|NP_645950.1| DNA topoisomerase I topA homolog~OR... 123 2e-26
gi|2828232|emb|CAA71737.1| topoisomerase I [Helicobacter pylori] 123 2e-26
gi|30018625|ref|NP_830256.1| DNA topoisomerase I [Bacillus cereu... 123 2e-26
gi|45915558|ref|ZP_00194253.2| COG0550: Topoisomerase IA [Mesorh... 123 2e-26
gi|47092646|ref|ZP_00230433.1| DNA topoisomerase III [Listeria m... 123 2e-26
gi|46908943|ref|YP_015332.1| DNA topoisomerase III [Listeria mon... 123 2e-26
gi|29831164|ref|NP_825798.1| putative DNA topoisomerase I [Strep... 123 2e-26
gi|46112809|ref|ZP_00181891.2| COG0550: Topoisomerase IA [Exiguo... 122 3e-26
gi|47570334|ref|ZP_00240979.1| DNA topoisomerase I [Bacillus cer... 122 3e-26
gi|49478403|ref|YP_037894.1| DNA topoisomerase I [Bacillus thuri... 122 4e-26
gi|42782925|ref|NP_980172.1| DNA topoisomerase I [Bacillus cereu... 122 4e-26
gi|15806391|ref|NP_295097.1| DNA topoisomerase I [Deinococcus ra... 122 4e-26
gi|15644746|ref|NP_206916.1| DNA topoisomerase I (topA) [Helicob... 122 4e-26
gi|21244531|ref|NP_644113.1| DNA topoisomerase I [Xanthomonas ax... 122 4e-26
gi|42561447|ref|NP_975898.1| DNA topoisomerase I [Mycoplasma myc... 122 5e-26
gi|42519034|ref|NP_964964.1| DNA topoisomerase I [Lactobacillus ... 122 5e-26
gi|21401816|ref|NP_657801.1| Topoisom_bac, DNA topoisomerase [Ba... 122 5e-26
gi|15896200|ref|NP_349549.1| Topoisomerase B [Clostridium acetob... 122 5e-26
gi|19704404|ref|NP_603966.1| DNA topoisomerase I [Fusobacterium ... 122 5e-26
gi|46445705|ref|YP_007070.1| putative DNA topoisomerase I [Parac... 122 5e-26
gi|30021921|ref|NP_833552.1| DNA topoisomerase I [Bacillus cereu... 122 5e-26
gi|42779565|ref|NP_976812.1| DNA topoisomerase III [Bacillus cer... 122 5e-26
gi|22957761|ref|ZP_00005451.1| COG0550: Topoisomerase IA [Rhodob... 121 6e-26
gi|48894736|ref|ZP_00327845.1| COG0550: Topoisomerase IA [Tricho... 121 6e-26
gi|47567196|ref|ZP_00237910.1| DNA topoisomerase I [Bacillus cer... 121 6e-26
gi|33860993|ref|NP_892554.1| Prokaryotic DNA topoisomerase [Proc... 121 8e-26
gi|48866983|ref|ZP_00320637.1| COG0550: Topoisomerase IA [Haemop... 121 8e-26
gi|29348236|ref|NP_811739.1| DNA topoisomerase I [Bacteroides th... 121 8e-26
gi|49237011|ref|ZP_00331067.1| COG0550: Topoisomerase IA [Moorel... 120 1e-25
gi|23127940|ref|ZP_00109797.1| COG0550: Topoisomerase IA [Nostoc... 120 1e-25
gi|26990724|ref|NP_746149.1| DNA topoisomerase III [Pseudomonas ... 120 1e-25
gi|17230272|ref|NP_486820.1| DNA topoisomerase I [Nostoc sp. PCC... 120 1e-25
gi|15611178|ref|NP_222829.1| DNA TOPOISOMERASE I [Helicobacter p... 120 1e-25
gi|32475123|ref|NP_868117.1| DNA topoisomerase I [Pirellula sp. ... 120 1e-25
gi|18976866|ref|NP_578223.1| DNA topoisomerase I [Pyrococcus fur... 120 1e-25
gi|15618678|ref|NP_224964.1| DNA Topoisomerase I-Fused to SWI Do... 120 1e-25
gi|3309559|gb|AAC26106.1| DNA topoisomerase I [Pyrococcus furiosus] 120 1e-25
gi|30260542|ref|NP_842919.1| DNA topoisomerase III [Bacillus ant... 120 2e-25
gi|28897796|ref|NP_797401.1| DNA topoisomerase I [Vibrio parahae... 120 2e-25
gi|15897795|ref|NP_342400.1| DNA topoisomerase I family A (topA)... 120 2e-25
gi|37526330|ref|NP_929674.1| DNA topoisomerase I (omega protein)... 119 2e-25
gi|15641734|ref|NP_231366.1| DNA topoisomerase I [Vibrio cholera... 119 2e-25
gi|34557838|ref|NP_907653.1| DNA TOPOISOMERASE [Wolinella succin... 119 2e-25
gi|27380222|ref|NP_771751.1| DNA topoisomerase I [Bradyrhizobium... 119 3e-25
gi|15616895|ref|NP_240108.1| DNA topoisomerase I [Buchnera aphid... 119 3e-25
gi|46200233|ref|YP_005900.1| DNA topoisomerase I [Thermus thermo... 119 3e-25
gi|45523804|ref|ZP_00175134.1| COG0550: Topoisomerase IA [Crocos... 119 4e-25
gi|29345515|ref|NP_809018.1| DNA topoisomerase I (Omega-protein)... 119 4e-25
gi|24374246|ref|NP_718289.1| DNA topoisomerase I [Shewanella one... 119 4e-25
gi|48865025|ref|ZP_00318892.1| COG0550: Topoisomerase IA [Oenoco... 119 4e-25
gi|16803315|ref|NP_464800.1| highly similar to DNA topoisomerase... 118 5e-25
gi|27467844|ref|NP_764481.1| DNA topoisomerase I topA-like prote... 118 5e-25
gi|42526717|ref|NP_971815.1| DNA topoisomerase I [Treponema dent... 118 5e-25
gi|48866447|ref|ZP_00320303.1| COG0550: Topoisomerase IA [Oenoco... 118 7e-25
gi|16330456|ref|NP_441184.1| DNA topoisomerase I [Synechocystis ... 118 7e-25
gi|46907502|ref|YP_013891.1| DNA topoisomerase I [Listeria monoc... 118 7e-25
gi|16078675|ref|NP_389494.1| DNA topoisomerase I [Bacillus subti... 117 9e-25
gi|50119477|ref|YP_048644.1| putative DNA topoisomerase [Erwinia... 117 9e-25
gi|15602480|ref|NP_245552.1| TopA [Pasteurella multocida Pm70] >... 117 9e-25
gi|16800382|ref|NP_470650.1| highly similar to DNA topoisomerase... 117 9e-25
gi|46105856|ref|ZP_00199710.1| COG0550: Topoisomerase IA [Rubrob... 117 1e-24
gi|42522529|ref|NP_967909.1| DNA topoisomerase I [Bdellovibrio b... 117 1e-24
gi|48856761|ref|ZP_00310918.1| COG0550: Topoisomerase IA [Cytoph... 117 1e-24
gi|47093924|ref|ZP_00231663.1| DNA topoisomerase I [Listeria mon... 117 1e-24
gi|48862061|ref|ZP_00315959.1| COG0550: Topoisomerase IA [Microb... 117 2e-24
gi|45509397|ref|ZP_00161731.1| COG0550: Topoisomerase IA [Anabae... 117 2e-24
gi|32267297|ref|NP_861329.1| DNA topoisomerase I [Helicobacter h... 117 2e-24
gi|45505667|ref|ZP_00158039.1| COG0550: Topoisomerase IA [Anabae... 116 2e-24
gi|27365461|ref|NP_760989.1| DNA topoisomerase I [Vibrio vulnifi... 116 2e-24
gi|15605375|ref|NP_220161.1| DNA Topoisomerase I-Fused to SWI Do... 116 3e-24
gi|22996953|ref|ZP_00041194.1| COG0550: Topoisomerase IA [Xylell... 115 3e-24
gi|23500348|ref|NP_699788.1| DNA topoisomerase I [Brucella suis ... 115 3e-24
gi|48830928|ref|ZP_00288020.1| COG0550: Topoisomerase IA [Magnet... 115 3e-24
gi|45515733|ref|ZP_00167287.1| COG0550: Topoisomerase IA [Ralsto... 115 5e-24
gi|17989011|ref|NP_541644.1| DNA TOPOISOMERASE I [Brucella melit... 115 5e-24
gi|21672896|ref|NP_660961.1| DNA topoisomerase I [Chlorobium tep... 115 5e-24
gi|37680498|ref|NP_935107.1| DNA topoisomerase I [Vibrio vulnifi... 115 5e-24
gi|28199638|ref|NP_779952.1| DNA topoisomerase I [Xylella fastid... 115 6e-24
gi|21910356|ref|NP_664624.1| putative DNA topoisomerase I [Strep... 115 6e-24
gi|48733576|ref|ZP_00267319.1| COG0550: Topoisomerase IA [Pseudo... 114 8e-24
gi|15837522|ref|NP_298210.1| DNA topoisomerase I [Xylella fastid... 114 8e-24
gi|19746110|ref|NP_607246.1| putative DNA topoisomerase I [Strep... 114 8e-24
gi|48825559|ref|ZP_00286803.1| COG0550: Topoisomerase IA [Entero... 114 1e-23
gi|45723572|emb|CAG17853.1| DNA topoisomerase [Lactobacillus pla... 114 1e-23
gi|48788126|ref|ZP_00284105.1| COG0550: Topoisomerase IA [Burkho... 114 1e-23
gi|42520935|ref|NP_966850.1| DNA topoisomerase I [Wolbachia endo... 114 1e-23
gi|22994870|ref|ZP_00039358.1| COG0550: Topoisomerase IA [Xylell... 114 1e-23
gi|10957138|ref|NP_047305.1| trsI protein (traI) [Lactococcus la... 114 1e-23
gi|17230123|ref|NP_486671.1| DNA topoisomerase I [Nostoc sp. PCC... 114 1e-23
gi|15675140|ref|NP_269314.1| putative DNA topoisomerase I [Strep... 113 2e-23
gi|24461748|gb|AAN62317.1| putative DNA topoisomerase III [Pseud... 113 2e-23
gi|21672553|ref|NP_660620.1| DNA topoisomerase I [Buchnera aphid... 113 2e-23
gi|30249913|ref|NP_841983.1| topB; DNA topoisomerase III protein... 113 2e-23
gi|46581790|ref|YP_012598.1| DNA topoisomerase I [Desulfovibrio ... 113 2e-23
gi|16077493|ref|NP_388307.1| DNA topoisomerase III [Bacillus sub... 113 2e-23
gi|23111296|ref|ZP_00096982.1| COG0550: Topoisomerase IA [Desulf... 112 3e-23
gi|23472389|ref|ZP_00127715.1| COG0550: Topoisomerase IA [Pseudo... 112 3e-23
gi|50590174|ref|ZP_00331590.1| COG0550: Topoisomerase IA [Strept... 112 4e-23
gi|48771508|ref|ZP_00275850.1| COG0550: Topoisomerase IA [Ralsto... 112 4e-23
gi|39936187|ref|NP_948463.1| DNA topoisomerase I [Rhodopseudomon... 112 4e-23
gi|48870543|ref|ZP_00323264.1| COG0550: Topoisomerase IA [Pedioc... 112 5e-23
gi|37525022|ref|NP_928366.1| hypothetical protein [Photorhabdus ... 112 5e-23
gi|46200755|ref|ZP_00056434.2| COG0550: Topoisomerase IA [Magnet... 111 7e-23
gi|47458917|ref|YP_015779.1| DNA topoisomerase I [Mycoplasma mob... 111 7e-23
gi|27804881|gb|AAO22915.1| topoisomerase [Myxococcus xanthus] 111 7e-23
gi|50841733|ref|YP_054960.1| DNA topoisomerase I [Propionibacter... 111 7e-23
gi|13508000|ref|NP_109949.1| DNA topoisomerase I [Mycoplasma pne... 111 9e-23
gi|16763007|ref|NP_458624.1| topoisomerase B [Salmonella enteric... 111 9e-23
gi|37522767|ref|NP_926144.1| DNA topoisomerase I [Gloeobacter vi... 110 1e-22
gi|15610782|ref|NP_218163.1| topA [Mycobacterium tuberculosis H3... 110 1e-22
gi|15965053|ref|NP_385406.1| PUTATIVE DNA TOPOISOMERASE I PROTEI... 110 1e-22
gi|32029739|ref|ZP_00132712.1| COG0550: Topoisomerase IA [Haemop... 110 1e-22
gi|48831484|ref|ZP_00288546.1| COG0550: Topoisomerase IA [Magnet... 110 2e-22
gi|15896801|ref|NP_350150.1| Topoisomerase B [Clostridium acetob... 110 2e-22
gi|29376204|ref|NP_815358.1| DNA topoisomerase I [Enterococcus f... 110 2e-22
gi|15828942|ref|NP_326302.1| DNA TOPOISOMERASE I (OMEGA-PROTEIN)... 109 3e-22
gi|32470416|ref|NP_863632.1| putative topoisomerase TraI [Staphy... 109 3e-22
gi|21242947|ref|NP_642529.1| DNA topoisomerase III [Xanthomonas ... 109 3e-22
gi|33239884|ref|NP_874826.1| Topoisomerase IA [Prochlorococcus m... 109 3e-22
gi|16549049|emb|CAC81788.1| Exc protein [Bacteroides sp.] >gnl|B... 109 3e-22
gi|15834637|ref|NP_296396.1| DNA topoisomerase I [Chlamydia muri... 108 4e-22
gi|27262274|gb|AAN87418.1| DNA topoisomerase I [Heliobacillus mo... 108 6e-22
gi|48836060|ref|ZP_00293057.1| COG0550: Topoisomerase IA [Thermo... 108 6e-22
gi|15888629|ref|NP_354310.1| AGR_C_2398p [Agrobacterium tumefaci... 108 6e-22
gi|23473122|ref|ZP_00128418.1| COG0551: Zn-finger domain associa... 108 6e-22
gi|50365469|ref|YP_053894.1| DNA topoisomerase I [Mesoplasma flo... 108 6e-22
gi|17544785|ref|NP_518187.1| PROBABLE DNA TOPOISOMERASE III PROT... 108 6e-22
gi|39938765|ref|NP_950531.1| topoisomerase IA [Onion yellows phy... 107 1e-21
gi|48733258|ref|ZP_00267001.1| COG0550: Topoisomerase IA [Pseudo... 107 1e-21
gi|46364537|ref|ZP_00227140.1| COG0550: Topoisomerase IA [Kineoc... 107 1e-21
gi|15838651|ref|NP_299339.1| conjugal transfer protein [Xylella ... 107 1e-21
gi|48824911|ref|ZP_00286232.1| COG0550: Topoisomerase IA [Entero... 107 1e-21
gi|28869671|ref|NP_792290.1| DNA topoisomerase III [Pseudomonas ... 107 1e-21
gi|1395205|gb|AAC44599.1| topoisomerase I 107 2e-21
gi|26553866|ref|NP_757800.1| DNA topoisomerase I [Mycoplasma pen... 106 2e-21
gi|29423771|gb|AAO73480.1| DNA topoisomerase I [Sulfolobus acido... 106 3e-21
gi|29347734|ref|NP_811237.1| DNA topoisomerase III [Bacteroides ... 106 3e-21
gi|22299424|ref|NP_682671.1| DNA topoisomerase I [Thermosynechoc... 106 3e-21
gi|23468684|ref|ZP_00124019.1| COG0550: Topoisomerase IA [Pseudo... 105 4e-21
gi|15827005|ref|NP_301268.1| putative DNA topoisomerase I [Mycob... 105 4e-21
gi|23106374|ref|ZP_00092828.1| COG0550: Topoisomerase IA [Azotob... 105 5e-21
gi|29840743|ref|NP_829849.1| DNA topoisomerase I [Chlamydophila ... 105 5e-21
gi|29348054|ref|NP_811557.1| DNA topoisomerase I [Bacteroides th... 105 5e-21
gi|48786298|ref|ZP_00282432.1| COG0550: Topoisomerase IA [Burkho... 105 5e-21
gi|23111667|ref|ZP_00097269.1| COG0550: Topoisomerase IA [Desulf... 105 6e-21
gi|24461623|gb|AAN62194.1| putative DNA topoisomerase III [Pseud... 104 8e-21
gi|14601370|ref|NP_147906.1| reverse gyrase [Aeropyrum pernix K1... 104 1e-20
gi|2145593|pir||S68603 hypothetical protein gamma - Streptococcu... 103 1e-20
gi|41614841|ref|NP_963339.1| NEQ045 [Nanoarchaeum equitans Kin4-... 103 2e-20
gi|37520589|ref|NP_923966.1| DNA topoisomerase I [Gloeobacter vi... 103 2e-20
gi|7531209|sp|O34204|TOP1_FERIS DNA topoisomerase I (Omega-prote... 103 2e-20
gi|28898923|ref|NP_798528.1| DNA topoisomerase III [Vibrio parah... 103 2e-20
gi|28378508|ref|NP_785400.1| DNA topoisomerase [Lactobacillus pl... 103 2e-20
gi|16764649|ref|NP_460264.1| DNA topoisomerase III [Salmonella t... 102 3e-20
gi|47572213|ref|ZP_00242258.1| COG0550: Topoisomerase IA [Rubriv... 102 4e-20
gi|7109696|gb|AAF36767.1| DNA topoisomerase I [Mycoplasma gallis... 102 4e-20
gi|15595173|ref|NP_212962.1| DNA topoisomerase I (topA) [Borreli... 102 5e-20
gi|31544838|ref|NP_853416.1| TopA [Mycoplasma gallisepticum R] >... 102 5e-20
gi|46322778|ref|ZP_00223145.1| COG0550: Topoisomerase IA [Burkho... 102 5e-20
gi|46914079|emb|CAG20859.1| putative DNA topoisomerase I [Photob... 102 5e-20
gi|10955488|ref|NP_065340.1| DNA topoisomerase III [Escherichia ... 102 5e-20
gi|47568294|ref|ZP_00238996.1| DNA topoisomerase III [Bacillus c... 101 7e-20
gi|46308445|ref|ZP_00210638.1| COG0550: Topoisomerase IA [Ehrlic... 101 9e-20
gi|15639385|ref|NP_218834.1| DNA topoisomerase I (topA) [Trepone... 101 9e-20
gi|3023050|gb|AAC38606.1| type I topoisomerase [Enterococcus fae... 101 9e-20
gi|48766910|ref|ZP_00271285.1| COG0550: Topoisomerase IA [Ralsto... 100 1e-19
gi|16129717|ref|NP_416277.1| DNA topoisomerase III; DNA topoisom... 100 1e-19
gi|30062974|ref|NP_837145.1| DNA topoisomerase III [Shigella fle... 100 1e-19
gi|24112840|ref|NP_707350.1| DNA topoisomerase III [Shigella fle... 100 1e-19
gi|45441766|ref|NP_993305.1| DNA topoisomerase III [Yersinia pes... 100 2e-19
gi|12044974|ref|NP_072784.1| DNA topoisomerase I (topA) [Mycopla... 100 2e-19
gi|41615107|ref|NP_963605.1| NEQ318 [Nanoarchaeum equitans Kin4-... 100 2e-19
gi|15838376|ref|NP_299064.1| DNA topoisomerase III [Xylella fast... 100 2e-19
gi|16122397|ref|NP_405710.1| DNA topoisomerase III [Yersinia pes... 100 3e-19
gi|28212484|gb|AAF19045.2| DNA topoisomerase I [Mycoplasma galli... 100 3e-19
gi|33591673|ref|NP_879317.1| DNA topoisomerase iii [Bordetella p... 100 3e-19
gi|15802174|ref|NP_288196.1| DNA topoisomerase III [Escherichia ... 100 3e-19
gi|22126044|ref|NP_669467.1| DNA topoisomerase III [Yersinia pes... 100 3e-19
gi|26248020|ref|NP_754060.1| DNA topoisomerase III [Escherichia ... 99 3e-19
gi|50877506|emb|CAG37346.1| probable DNA topoisomerase III [Desu... 99 3e-19
gi|37526442|ref|NP_929786.1| DNA topoisomerase III [Photorhabdus... 99 3e-19
gi|14719499|pdb|1I7D|A Chain A, Noncovalent Complex Of E.Coli Dn... 99 3e-19
gi|16760597|ref|NP_456214.1| DNA topoisomerase III [Salmonella e... 99 3e-19
gi|32455810|ref|NP_862462.1| TraE protein [Pseudomonas sp. ADP] ... 99 3e-19
gi|46140996|ref|ZP_00152772.2| COG0550: Topoisomerase IA [Dechlo... 99 4e-19
gi|32469836|ref|NP_863308.1| TopA [Campylobacter jejuni] >gnl|BL... 99 4e-19
gi|46311010|ref|ZP_00211623.1| COG0550: Topoisomerase IA [Burkho... 99 4e-19
gi|47571360|ref|ZP_00241417.1| COG0550: Topoisomerase IA [Rubriv... 98 8e-19
gi|33598857|ref|NP_886500.1| DNA topoisomerase iii [Bordetella p... 98 8e-19
gi|33603934|ref|NP_891494.1| DNA topoisomerase iii [Bordetella b... 98 8e-19
gi|45657928|ref|YP_002014.1| DNA topoisomerase I protein [Leptos... 98 1e-18
gi|24214421|ref|NP_711902.1| DNA topoisomerase I [Leptospira int... 97 1e-18
gi|47573912|ref|ZP_00243949.1| COG0550: Topoisomerase IA [Rubriv... 97 1e-18
gi|34541162|ref|NP_905641.1| DNA topoisomerase III [Porphyromona... 97 2e-18
gi|29376814|ref|NP_815968.1| DNA topoisomerase III [Enterococcus... 96 4e-18
gi|27366396|ref|NP_761924.1| Topoisomerase IA [Vibrio vulnificus... 96 4e-18
gi|13358155|ref|NP_078429.1| DNA topoisomerase I [Ureaplasma par... 95 6e-18
gi|29347499|ref|NP_811002.1| DNA topoisomerase III [Bacteroides ... 95 6e-18
gi|8100667|gb|AAF72351.1| DNA topoisomerase III-like protein [En... 95 6e-18
gi|37679339|ref|NP_933948.1| topoisomerase IA [Vibrio vulnificus... 95 8e-18
gi|23467166|ref|ZP_00122750.1| COG0550: Topoisomerase IA [Haemop... 95 8e-18
gi|15081527|ref|NP_150040.1| type I topoisomease [Clostridium pe... 94 1e-17
gi|10956714|ref|NP_061659.1| topoisomerase I [Xylella fastidiosa... 94 2e-17
gi|27468746|ref|NP_765383.1| DNA topoisomerase III topB [Staphyl... 94 2e-17
gi|48862690|ref|ZP_00316585.1| COG0550: Topoisomerase IA [Microb... 94 2e-17
gi|15606221|ref|NP_213599.1| reverse gyrase [Aquifex aeolicus VF... 94 2e-17
gi|46323909|ref|ZP_00224272.1| COG0550: Topoisomerase IA [Burkho... 93 2e-17
gi|37955683|gb|AAP22522.1| putative TopA topoisomerase [Pseudomo... 92 4e-17
gi|47097418|ref|ZP_00234967.1| DNA topoisomerase I [Listeria mon... 92 5e-17
gi|34539972|ref|NP_904451.1| DNA topoisomerase III [Porphyromona... 92 5e-17
gi|18310965|ref|NP_562899.1| DNA topoisomerase III-like protein ... 91 9e-17
gi|49484470|ref|YP_041694.1| putative DNA topoisomerase [Staphyl... 91 1e-16
gi|15925244|ref|NP_372778.1| DNA topoisomerase III topB [Staphyl... 91 1e-16
gi|42567296|ref|NP_194849.2| DNA topoisomerase family protein [A... 91 1e-16
gi|15602072|ref|NP_245144.1| TopB [Pasteurella multocida Pm70] >... 91 1e-16
gi|32481703|gb|AAP84217.1| topoisomerase I [Pseudomonas aeruginosa] 91 1e-16
gi|37703913|gb|AAR01278.1| DNA topoisomerase I [Pseudomonas aeru... 90 3e-16
gi|11498629|ref|NP_069857.1| reverse gyrase (top-RG) [Archaeoglo... 90 3e-16
gi|28211475|ref|NP_782419.1| DNA topoisomerase I [Clostridium te... 90 3e-16
gi|46143239|ref|ZP_00135618.2| COG0550: Topoisomerase IA [Actino... 90 3e-16
gi|50121265|ref|YP_050432.1| DNA topoisomerase III [Erwinia caro... 90 3e-16
gi|23465075|ref|NP_695678.1| DNA topoisomerase I [Bifidobacteriu... 89 5e-16
gi|42559430|sp|P74759|RGYR_SULSH Reverse gyrase [Includes: Helic... 89 5e-16
gi|46190552|ref|ZP_00121375.2| COG0550: Topoisomerase IA [Bifido... 89 5e-16
gi|464903|sp|P34184|TOP1_BACPF DNA topoisomerase I (Omega-protei... 89 6e-16
gi|16769908|gb|AAL29173.1| SD10251p [Drosophila melanogaster] 88 8e-16
gi|23127262|ref|ZP_00109136.1| COG0550: Topoisomerase IA [Nostoc... 87 1e-15
gi|42632068|ref|ZP_00157606.1| COG0550: Topoisomerase IA [Haemop... 87 2e-15
gi|16751934|ref|NP_444518.1| TraB protein [Plasmid pIPO2T] >gnl|... 87 2e-15
gi|16272392|ref|NP_438605.1| DNA topoisomerase III [Haemophilus ... 87 2e-15
gi|7524019|pir||S23866 probable DNA topoisomerase (EC 5.99.1.2) ... 86 3e-15
gi|14521467|ref|NP_126943.1| reverse gyrase [Pyrococcus abyssi G... 86 4e-15
gi|20149846|pdb|1GL9|B Chain B, Archaeoglobus Fulgidus Reverse G... 86 4e-15
gi|20149845|pdb|1GKU|B Chain B, Reverse Gyrase From Archaeoglobu... 86 4e-15
gi|32039770|ref|ZP_00138042.1| COG0550: Topoisomerase IA [Pseudo... 86 4e-15
gi|23023617|ref|ZP_00062850.1| COG0550: Topoisomerase IA [Leucon... 86 5e-15
gi|42629901|ref|ZP_00155446.1| COG0550: Topoisomerase IA [Haemop... 86 5e-15
gi|15919991|ref|NP_361051.1| TraB protein [Plasmid pSB102] >gnl|... 86 5e-15
gi|33152358|ref|NP_873711.1| DNA topoisomerase III [Haemophilus ... 85 9e-15
gi|42630741|ref|ZP_00156280.1| COG0550: Topoisomerase IA [Haemop... 85 9e-15
gi|18312412|ref|NP_559079.1| reverse gyrase [Pyrobaculum aerophi... 85 9e-15
gi|18976867|ref|NP_578224.1| reverse gyrase [Pyrococcus furiosus... 84 1e-14
gi|38491975|gb|AAR22322.1| topoisomerase I [Helicobacter pylori] 82 4e-14
gi|7484926|pir||T04488 DNA topoisomerase homolog F8F16.30 - Arab... 82 4e-14
gi|1698674|gb|AAB49283.1| reverse gyrase [Pyrococcus furiosus] 82 4e-14
gi|15606410|ref|NP_213790.1| reverse gyrase [Aquifex aeolicus VF... 82 6e-14
gi|42559341|sp|O67226|RGY2_AQUAE Reverse gyrase 2 [Includes: Hel... 82 6e-14
gi|15897842|ref|NP_342447.1| Reverse gyrase (topR-2) [Sulfolobus... 82 6e-14
gi|48823790|ref|ZP_00285277.1| COG0550: Topoisomerase IA [Entero... 82 7e-14
gi|39979738|gb|AAR29581.1| cpp49 [Campylobacter jejuni] 82 7e-14
gi|39979688|gb|AAR29532.1| cpp49 [Campylobacter coli] 82 7e-14
gi|44004479|ref|NP_982147.1| DNA topoisomerase I [Bacillus cereu... 81 1e-13
gi|15897352|ref|NP_341957.1| Reverse gyrase (topR-1) [Sulfolobus... 81 1e-13
gi|464904|sp|P34185|TOP1_SYNP7 DNA topoisomerase I (Omega-protei... 80 2e-13
gi|1085753|pir||S41543 DNA topoisomerase (EC 5.99.1.2) - Bacillu... 80 2e-13
gi|10956388|ref|NP_052837.1| pXO1-142 [Bacillus anthracis] >gnl|... 80 2e-13
gi|15611996|ref|NP_223648.1| topoisomerase I [Helicobacter pylor... 80 2e-13
gi|15642947|ref|NP_227988.1| reverse gyrase [Thermotoga maritima... 80 2e-13
gi|79965|pir||PQ0259 hypothetical protein I - Enterococcus faeca... 77 2e-12
gi|22973723|ref|ZP_00020247.1| hypothetical protein [Chloroflexu... 77 2e-12
gi|21392886|ref|NP_652966.1| DNA topoisomerase I [Bacillus anthr... 76 3e-12
gi|33152093|ref|NP_873446.1| DNA topoisomerase III [Haemophilus ... 76 3e-12
gi|23475952|ref|ZP_00131206.1| COG0550: Topoisomerase IA [Desulf... 76 3e-12
gi|21398326|ref|NP_654311.1| Topoisom_bac, DNA topoisomerase [Ba... 75 7e-12
gi|50755617|ref|XP_414822.1| PREDICTED: similar to topoisomerase... 75 7e-12
gi|47197825|emb|CAF88212.1| unnamed protein product [Tetraodon n... 74 2e-11
gi|20808164|ref|NP_623335.1| Reverse gyrase [Thermoanaerobacter ... 73 3e-11
gi|7245304|pdb|1CY9|A Chain A, Crystal Structure Of The 30 Kda F... 72 8e-11
gi|586108|sp|Q08582|RGYR_SULAC Reverse gyrase [Includes: Helicas... 71 1e-10
gi|15611986|ref|NP_223637.1| topoisomerase I [Helicobacter pylor... 70 3e-10
gi|39937196|ref|NP_949472.1| possible DNA topoisomerase [Rhodops... 70 3e-10
gi|46191286|ref|ZP_00206745.1| COG0550: Topoisomerase IA [Bifido... 69 4e-10
gi|23466025|ref|NP_696628.1| DNA topoisomerase III [Bifidobacter... 69 4e-10
gi|32394536|gb|AAM93966.1| DNA topoisomerase III [Griffithsia ja... 69 4e-10
gi|10955240|ref|NP_044269.1| TraE [Enterobacter aerogenes] >gnl|... 68 8e-10
gi|48858650|ref|ZP_00312599.1| COG0550: Topoisomerase IA [Clostr... 67 1e-09
gi|15921555|ref|NP_377224.1| 1156aa long hypothetical reverse gy... 66 4e-09
gi|46324250|ref|ZP_00224611.1| COG0550: Topoisomerase IA [Burkho... 66 4e-09
gi|22974428|ref|ZP_00020679.1| hypothetical protein [Chloroflexu... 66 4e-09
gi|15669706|ref|NP_248519.1| reverse gyrase, intein containing (... 65 9e-09
gi|15645068|ref|NP_207238.1| DNA topoisomerase I (topA) [Helicob... 64 1e-08
gi|14601344|ref|NP_147880.1| reverse gyrase [Aeropyrum pernix K1... 63 3e-08
gi|20093729|ref|NP_613576.1| Reverse gyrase [Methanopyrus kandle... 62 8e-08
gi|22993740|ref|ZP_00038290.1| COG0550: Topoisomerase IA [Xylell... 60 2e-07
gi|21398325|ref|NP_654310.1| Topoisom_bac, DNA topoisomerase [Ba... 60 2e-07
gi|1173901|gb|AAA96962.1| reverse gyrase A subunit 60 2e-07
gi|12956997|emb|CAC29167.1| putative topoisomerase I [Enterococc... 59 5e-07
gi|28198920|ref|NP_779234.1| truncated conjugal transfer protein... 58 1e-06
gi|41689086|ref|ZP_00145621.1| COG0551: Zn-finger domain associa... 58 1e-06
gi|22993739|ref|ZP_00038289.1| COG0550: Topoisomerase IA [Xylell... 58 1e-06
gi|48866792|ref|ZP_00320512.1| COG0550: Topoisomerase IA [Haemop... 57 1e-06
gi|47568295|ref|ZP_00238997.1| DNA topoisomerase III [Bacillus c... 57 3e-06
gi|22994238|ref|ZP_00038750.1| COG0550: Topoisomerase IA [Xylell... 57 3e-06
gi|10956466|ref|NP_053231.1| pXO2-77 [Bacillus anthracis] >gnl|B... 55 7e-06
gi|49532704|dbj|BAD26706.1| reverse gyrase [Thermococcus kodakar... 54 2e-05
gi|23024757|ref|ZP_00063954.1| COG0550: Topoisomerase IA [Leucon... 52 5e-05
gi|10956211|ref|NP_053003.1| ORF3 [Streptococcus agalactiae] >gn... 52 6e-05
gi|10956465|ref|NP_053230.1| pXO2-76 [Bacillus anthracis] >gnl|B... 51 1e-04
gi|48864820|ref|ZP_00318693.1| COG0550: Topoisomerase IA [Oenoco... 50 2e-04
gi|14590668|ref|NP_142736.1| reverse gyrase [Pyrococcus horikosh... 50 2e-04
gi|23127263|ref|ZP_00109137.1| COG0550: Topoisomerase IA [Nostoc... 50 2e-04
gi|49477338|ref|YP_035921.1| DNA topoisomerase I [Bacillus thuri... 49 5e-04
gi|39485|emb|CAA78485.1| DNA topoisomerase I [Bacillus firmus] 49 5e-04
gi|48823737|ref|ZP_00285244.1| COG0550: Topoisomerase IA [Entero... 49 5e-04
gi|47227488|emb|CAG04636.1| unnamed protein product [Tetraodon n... 48 0.001
gi|12956994|emb|CAC29165.1| putative topoisomerase I [Enterococc... 48 0.001
gi|19353217|gb|AAH24921.1| Putative DNA glycosylase [Mus musculus] 47 0.002
gi|22122759|ref|NP_666320.1| putative DNA glycosylase [Mus muscu... 47 0.002
gi|38016158|ref|NP_619643.2| prematurely terminated mRNA decay f... 47 0.002
gi|46580721|ref|YP_011529.1| DNA topoisomerase III [Desulfovibri... 47 0.002
gi|34878386|ref|XP_224835.2| similar to putative DNA glycosylase... 46 0.003
gi|34859985|ref|XP_227717.2| similar to hypothetical protein FLJ... 46 0.004
gi|50746881|ref|XP_426326.1| PREDICTED: similar to prematurely t... 45 0.010
gi|19684059|gb|AAH25954.1| DNA glycosylase hFPG2 [Homo sapiens] 44 0.017
gi|8922722|ref|NP_060718.1| DNA glycosylase hFPG2 [Homo sapiens]... 44 0.017
gi|41053341|ref|NP_956318.1| DEAH (Asp-Glu-Ala-His) box polypept... 44 0.017
gi|22004059|dbj|BAC06479.1| hypothetical protein [Homo sapiens] 44 0.017
gi|50746841|ref|XP_426306.1| PREDICTED: similar to DNA glycosyla... 43 0.038
gi|31983879|ref|NP_858487.1| Type 1 DNA topoisomerase [Rhodococc... 42 0.049
gi|10956649|ref|NP_066785.1| type 1 DNA topoisomerase-like prote... 42 0.084
gi|27675350|ref|XP_223499.1| similar to apurinic/apyrimidinic en... 42 0.084
gi|32420515|ref|XP_330701.1| predicted protein [Neurospora crass... 42 0.084
gi|38102777|gb|EAA49574.1| predicted protein [Magnaporthe grisea... 40 0.19
gi|5410346|gb|AAD43041.1| APE2 protein [Homo sapiens] 40 0.24
gi|18375507|ref|NP_055296.2| apurinic/apyrimidinic endonuclease ... 40 0.24
gi|47206818|emb|CAF91198.1| unnamed protein product [Tetraodon n... 40 0.32
gi|42453584|ref|ZP_00153491.1| hypothetical protein Rick043901 [... 40 0.32
gi|26354044|dbj|BAC40652.1| unnamed protein product [Mus musculus] 39 0.42
>gi|17555378|ref|NP_499558.1| TOPoisomerase (85.4 kD) (top-3)
[Caenorhabditis elegans]
gi|6686028|sp|O61660|TOP3_CAEEL DNA topoisomerase III
gi|11270818|pir||T43031 DNA topoisomerase (EC 5.99.1.2) III -
Caenorhabditis elegans
gi|3047013|gb|AAC13567.1| DNA topoisomerase III [Caenorhabditis
elegans]
gi|14530655|emb|CAB60518.2| Hypothetical protein Y56A3A.27
[Caenorhabditis elegans]
Length = 759
Score = 1360 bits (3519), Expect = 0.0
Identities = 692/759 (91%), Positives = 692/759 (91%)
Frame = -1
Query: 2280 MKRALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGH 2101
MKRALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGH
Sbjct: 1 MKRALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGH 60
Query: 2100 MMNFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDRE 1921
MMNFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDRE
Sbjct: 61 MMNFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDRE 120
Query: 1920 GEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDL 1741
GEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDL
Sbjct: 121 GEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDL 180
Query: 1740 RIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFW 1561
RIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFW
Sbjct: 181 RIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFW 240
Query: 1560 KLIVEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALD 1381
KLIVEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALD
Sbjct: 241 KLIVEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALD 300
Query: 1380 TVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNI 1201
TVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNI
Sbjct: 301 TVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNI 360
Query: 1200 WGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQ 1021
WGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQ
Sbjct: 361 WGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQ 420
Query: 1020 DAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKI 841
DAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKI
Sbjct: 421 DAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKI 480
Query: 840 GDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLA 661
GDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLA
Sbjct: 481 GDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLA 540
Query: 660 LVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVL 481
LVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVL
Sbjct: 541 LVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVL 600
Query: 480 SQSLQRYLDKNNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKS 301
SQSLQRYLDKNNQ KS
Sbjct: 601 SQSLQRYLDKNNQAGGGPGGPGGGGGPPRGPGGGGGGGPTGPPAPPKPPAKPRGRPPRKS 660
Query: 300 ISPAVKNGHDDPENDTIVTLSEVFGSMSNXXXXXXXXXXXXXXXXKXXXXXXEVFCQCPE 121
ISPAVKNGHDDPENDTIVTLSEVFGSMSN K EVFCQCPE
Sbjct: 661 ISPAVKNGHDDPENDTIVTLSEVFGSMSNPKPARKPRAPRKSAAPKEQEEEEEVFCQCPE 720
Query: 120 PMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKWA 4
PMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKWA
Sbjct: 721 PMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKWA 759
>gi|39584856|emb|CAE67751.1| Hypothetical protein CBG13326
[Caenorhabditis briggsae]
Length = 753
Score = 1202 bits (3110), Expect = 0.0
Identities = 608/758 (80%), Positives = 649/758 (85%)
Frame = -1
Query: 2280 MKRALFVAEKNDVAKGVAAILSNGTANRREGRSKFNKIYTLNTELFGQQTAISVTSVSGH 2101
MKRALFVAEKNDVAKGVAAILSNGT+NR+EG+SKFNKIYTLN+ELFGQ+ AISVTSVSGH
Sbjct: 1 MKRALFVAEKNDVAKGVAAILSNGTSNRKEGKSKFNKIYTLNSELFGQRAAISVTSVSGH 60
Query: 2100 MMNFQFHENMSNWQTASMVELFRAPVRHVVTPEMKLIEQTLREQAQRHDILVVWTDCDRE 1921
+MN+QFHENMSNWQT SMVELF APVRHVVTP+MKLIE+TLRE+AQRHD+LVVWTDCDRE
Sbjct: 61 LMNWQFHENMSNWQTTSMVELFEAPVRHVVTPDMKLIEKTLREEAQRHDVLVVWTDCDRE 120
Query: 1920 GEAIGAEIVKVCRDSNRRLDIFRARFSEITKAAITRAARNLIRLDEKTVAAVDCRSELDL 1741
GEAIGAEIVKVCR+SNRR+DI+RARFSEITKAAITRAARNLIRLDEK VAAVDCRSELDL
Sbjct: 121 GEAIGAEIVKVCRESNRRIDIYRARFSEITKAAITRAARNLIRLDEKIVAAVDCRSELDL 180
Query: 1740 RIGSAFTRLQTLHLRNRFRDLLGQNDTSQVISYGSCQFPTLGFVTDRYKMIENFVSEPFW 1561
RIGSAFTRLQTLHLRNRF LLGQ+D+S+VISYGSCQFPTLGFVTDRYK+IENF+SEPFW
Sbjct: 181 RIGSAFTRLQTLHLRNRFSSLLGQSDSSKVISYGSCQFPTLGFVTDRYKLIENFISEPFW 240
Query: 1560 KLIVEHTRESHKVEFLWDRNRLFDRDTVDILHDECKETKEAHVEKVAKKPKSKWRPQALD 1381
KL VEHTRE HKVEFLWDRNRLFDRD VDILHDECKE KEAHVEKV KKPKSKWRPQALD
Sbjct: 241 KLAVEHTREGHKVEFLWDRNRLFDRDVVDILHDECKEAKEAHVEKVTKKPKSKWRPQALD 300
Query: 1380 TVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPAGLNLTPLVQQQTQSNI 1201
TVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFP GLNLTPLV+QQ QS
Sbjct: 301 TVELEKLGISKLRMSAKQTMQVAEKLYSKGFISYPRTETNKFPPGLNLTPLVEQQVQSTT 360
Query: 1200 WGDFANEVLQNGVNPRNGRKSDEAHPPIHPLKFTEKHQLQGDDWKVYELVVRHFLACVSQ 1021
WGDFA EVLQ GV PRNG KSDEAHPPIHPL F +K+ L GDDWKVYELVVRHFLACVSQ
Sbjct: 361 WGDFATEVLQKGVTPRNGHKSDEAHPPIHPLTFADKNTLHGDDWKVYELVVRHFLACVSQ 420
Query: 1020 DAQGEETMVNLTVGTEKFHASGLRIRDMGYLKVYVYEKWGNRLLPTYTEGERFTDFELKI 841
DAQGEETMVNL VG+EKFH+SGLRIRDMGYLKVYVYEKWGNRLLPTY +GERF+D++LKI
Sbjct: 421 DAQGEETMVNLRVGSEKFHSSGLRIRDMGYLKVYVYEKWGNRLLPTYNQGERFSDYKLKI 480
Query: 840 GDGKTQAPDFLTEADLISLMDKYGIGTDATHAEHIEKIKTREYIGVRPDGKLIPSFLGLA 661
GDGKTQ PD LTEADLI+LMDK+GIGTDATHAEHIEKIKTREYIGV+PDGKLIPSFLGLA
Sbjct: 481 GDGKTQPPDLLTEADLIALMDKFGIGTDATHAEHIEKIKTREYIGVKPDGKLIPSFLGLA 540
Query: 660 LVDGYDDMGFAMSKPDLRANLEIGLKEICDGRRQKQEVLDEQIGKYRAIFVESERKIGVL 481
LVDGYDDMGFAMSKPDLRANLE+GLK+ICDGRRQKQEVLDEQIGKY++IFVESER I VL
Sbjct: 541 LVDGYDDMGFAMSKPDLRANLEMGLKDICDGRRQKQEVLDEQIGKYKSIFVESERNIEVL 600
Query: 480 SQSLQRYLDKNNQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKS 301
SQSLQRYL+KN Q KS
Sbjct: 601 SQSLQRYLNKNQQ---AGGGGGGGGGPPRGPGGGGGGGGSRGSGPPKPPPKPRGRQSKKS 657
Query: 300 ISPAVKNGHDDPENDTIVTLSEVFGSMSNXXXXXXXXXXXXXXXXKXXXXXXEVFCQCPE 121
SPA KN +NDTIVTLSEV GS++N EV C CPE
Sbjct: 658 KSPA-KNDDAGEDNDTIVTLSEVLGSLTN-PKPRKPRAPRKNGPNGLENEEEEVMCTCPE 715
Query: 120 PMRAVTKVVQKEGPNKGKKFYTCSLPYTSSEKCNFFKW 7
PM+AV KVVQKEGPNKGKKFYTCSLPYTSS+KCNFFKW
Sbjct: 716 PMKAVVKVVQKEGPNKGKKFYTCSLPYTSSDKCNFFKW 753