Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= Y108G3AL_5
(2334 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17566422|ref|NP_503151.1| cullin (90.2 kD) (cul-3) [Caenorhab... 1511 0.0
gi|1381138|gb|AAC47122.1| CUL-3 1503 0.0
gi|39592741|emb|CAE62355.1| Hypothetical protein CBG06434 [Caeno... 1292 0.0
gi|34876967|ref|XP_217454.2| similar to cullin 3 [Rattus norvegi... 712 0.0
gi|40788303|dbj|BAA31592.2| KIAA0617 protein [Homo sapiens] 711 0.0
gi|50418207|gb|AAH77239.1| Unknown (protein for MGC:79108) [Xeno... 711 0.0
gi|4503165|ref|NP_003581.1| cullin 3 [Homo sapiens] >gnl|BL_ORD_... 711 0.0
gi|39104526|dbj|BAC97984.2| mKIAA0617 protein [Mus musculus] 711 0.0
gi|7710014|ref|NP_057925.1| cullin 3 [Mus musculus] >gnl|BL_ORD_... 711 0.0
gi|40807151|gb|AAH65357.1| Cullin 3 [Danio rerio] 708 0.0
gi|41055488|ref|NP_955985.1| cullin 3 [Danio rerio] >gnl|BL_ORD_... 708 0.0
gi|49116945|gb|AAH73186.1| Unknown (protein for MGC:80402) [Xeno... 708 0.0
gi|31223774|ref|XP_317352.1| ENSANGP00000010476 [Anopheles gambi... 702 0.0
gi|17737421|ref|NP_523573.1| CG11861-PA [Drosophila melanogaster... 696 0.0
gi|33286088|gb|AAQ01660.1| cullin 3 isoform [Homo sapiens] 696 0.0
gi|50752026|ref|XP_422620.1| PREDICTED: similar to mKIAA0617 pro... 692 0.0
gi|3139079|gb|AAC36682.1| cullin 3 [Homo sapiens] 689 0.0
gi|46390116|dbj|BAD15552.1| putative cullin 3 [Oryza sativa (jap... 590 e-167
gi|40253773|dbj|BAD05712.1| putative cullin 3B [Oryza sativa (ja... 586 e-166
gi|38344878|emb|CAD41901.2| OSJNBa0033G05.2 [Oryza sativa (japon... 570 e-161
gi|15223361|ref|NP_174005.1| cullin, putative [Arabidopsis thali... 570 e-161
gi|15222412|ref|NP_177125.1| cullin, putative [Arabidopsis thali... 563 e-159
gi|1381146|gb|AAC50546.1| Hs-CUL-3 506 e-142
gi|47228293|emb|CAG07688.1| unnamed protein product [Tetraodon n... 462 e-128
gi|34481807|emb|CAC87839.1| cullin 3B [Arabidopsis thaliana] 455 e-126
gi|26376563|dbj|BAB28222.2| unnamed protein product [Mus musculus] 448 e-124
gi|50746004|ref|XP_420335.1| PREDICTED: similar to cullin 4B [Ga... 447 e-124
gi|29501811|ref|NP_082564.2| cullin 4B [Mus musculus] >gnl|BL_OR... 446 e-123
gi|31873759|emb|CAD97843.1| hypothetical protein [Homo sapiens] 444 e-123
gi|20521131|dbj|BAA31670.2| KIAA0695 protein [Homo sapiens] 444 e-123
gi|38176424|gb|AAR13073.1| cullin 4B [Homo sapiens] 443 e-123
gi|28372493|ref|NP_003579.2| cullin 4B; Cullin-4B [Homo sapiens]... 443 e-123
gi|13124703|sp|Q13620|CU4B_HUMAN Cullin homolog 4B (CUL-4B) 442 e-122
gi|34932780|ref|XP_228689.2| similar to cullin 4B; Cullin-4B [Ra... 441 e-122
gi|13259127|gb|AAK16812.1| cullin CUL4B [Homo sapiens] 439 e-121
gi|38176422|gb|AAR13072.1| cullin 4A [Homo sapiens] 429 e-118
gi|19113861|ref|NP_592949.1| cullin 3 homolog [Schizosaccharomyc... 416 e-114
gi|47230564|emb|CAF99757.1| unnamed protein product [Tetraodon n... 414 e-114
gi|39584719|emb|CAE72472.1| Hypothetical protein CBG19647 [Caeno... 414 e-114
gi|30524962|emb|CAC85265.1| cullin 4 [Arabidopsis thaliana] 409 e-112
gi|20268719|gb|AAM14063.1| putative cullin [Arabidopsis thaliana] 409 e-112
gi|18422645|ref|NP_568658.1| cullin, putative [Arabidopsis thali... 409 e-112
gi|2130361|pir||S62405 hypothetical protein SPAC24H6.03 - fissio... 407 e-112
gi|39104458|dbj|BAC41443.3| mKIAA0695 protein [Mus musculus] 400 e-110
gi|30584077|gb|AAP36287.1| Homo sapiens cullin 4A [synthetic con... 400 e-109
gi|11140811|ref|NP_003580.1| cullin 4A [Homo sapiens] >gnl|BL_OR... 400 e-109
gi|50355720|gb|AAT75245.1| putative cullin protein [Oryza sativa... 399 e-109
gi|31198403|ref|XP_308149.1| ENSANGP00000021534 [Anopheles gambi... 397 e-109
gi|13278441|gb|AAH04026.1| Cul4b protein [Mus musculus] 396 e-108
gi|48102664|ref|XP_392800.1| similar to ENSANGP00000021534 [Apis... 396 e-108
gi|24586500|ref|NP_610352.2| CG8711-PA [Drosophila melanogaster]... 393 e-107
gi|22164790|ref|NP_666319.1| cullin 4A [Mus musculus] >gnl|BL_OR... 384 e-105
gi|49093230|ref|XP_408076.1| hypothetical protein AN3939.2 [Aspe... 380 e-104
gi|50257156|gb|EAL19869.1| hypothetical protein CNBG0120 [Crypto... 378 e-103
gi|46105462|ref|XP_380535.1| hypothetical protein FG00359.1 [Gib... 376 e-102
gi|2340104|gb|AAB67315.1| Very similar and perhaps identical to ... 370 e-101
gi|47226214|emb|CAG08361.1| unnamed protein product [Tetraodon n... 369 e-100
gi|18848235|gb|AAH24113.1| Cul4a protein [Mus musculus] 361 5e-98
gi|9757989|dbj|BAB08502.1| cullin [Arabidopsis thaliana] 358 3e-97
gi|32425427|gb|AAH31844.1| CUL3 protein [Homo sapiens] 357 5e-97
gi|32422507|ref|XP_331697.1| hypothetical protein [Neurospora cr... 355 3e-96
gi|22550314|gb|AAL27655.2| putative cullin protein [Olea europaea] 343 1e-92
gi|41056097|ref|NP_957321.1| similar to cullin 4A [Danio rerio] ... 340 1e-91
gi|34481801|emb|CAC87836.1| cullin 1B [Nicotiana tabacum] 335 4e-90
gi|34914728|ref|NP_918711.1| cullin-like protein [Oryza sativa (... 334 6e-90
gi|34914732|ref|NP_918713.1| cullin-like protein [Oryza sativa (... 333 1e-89
gi|50545850|ref|XP_500463.1| hypothetical protein [Yarrowia lipo... 332 3e-89
gi|38107256|gb|EAA53454.1| hypothetical protein MG07731.4 [Magna... 331 5e-89
gi|34481799|emb|CAC87835.1| cullin 1A [Nicotiana tabacum] 331 5e-89
gi|3599676|dbj|BAA33146.1| cullin-4A [Homo sapiens] 330 1e-88
gi|34879447|ref|XP_341465.1| similar to KIAA0695 protein [Rattus... 329 2e-88
gi|22335691|dbj|BAC10548.1| cullin-like protein1 [Pisum sativum] 329 2e-88
gi|15291607|gb|AAK93072.1| GM14815p [Drosophila melanogaster] 324 5e-87
gi|18411983|ref|NP_567243.1| cullin family protein [Arabidopsis ... 323 1e-86
gi|1381142|gb|AAC50544.1| Hs-CUL-1 322 3e-86
gi|3093747|gb|AAC15412.1| CulA [Dictyostelium discoideum] 320 1e-85
gi|14091836|gb|AAK53839.1| Putative cullin [Oryza sativa] 319 2e-85
gi|47087291|ref|NP_998660.1| zgc:55483 [Danio rerio] >gnl|BL_ORD... 315 4e-84
gi|32307161|ref|NP_003583.2| cullin 1 [Homo sapiens] >gnl|BL_ORD... 313 2e-83
gi|7549752|ref|NP_036172.1| cullin 1 [Mus musculus] >gnl|BL_ORD_... 313 2e-83
gi|31873320|emb|CAD97651.1| hypothetical protein [Homo sapiens] 313 2e-83
gi|21466059|pdb|1LDJ|A Chain A, Structure Of The Cul1-Rbx1-Skp1-... 313 2e-83
gi|7489049|pir||T07163 probable cullin protein - tomato >gnl|BL_... 313 2e-83
gi|42820698|emb|CAF32011.1| scf complex protein, putative [Asper... 310 8e-83
gi|45433528|ref|NP_955953.2| cullin 1; wu:fc13a10 [Danio rerio] ... 310 1e-82
gi|32408159|ref|XP_324561.1| hypothetical protein [Neurospora cr... 307 8e-82
gi|28277699|gb|AAH45445.1| Cullin 1 [Danio rerio] 306 1e-81
gi|34855616|ref|XP_342680.1| similar to SCF complex protein cul-... 305 2e-81
gi|4959733|gb|AAD34471.1| cullin 1 [Mus musculus] 301 4e-80
gi|46136201|ref|XP_389792.1| hypothetical protein FG09616.1 [Gib... 301 4e-80
gi|38111175|gb|EAA56790.1| hypothetical protein MG07145.4 [Magna... 300 1e-79
gi|37589402|gb|AAH59348.1| MGC69167 protein [Xenopus laevis] 298 5e-79
gi|30962109|emb|CAC85344.1| cullin 3a [Arabidopsis thaliana] 297 9e-79
gi|19482174|ref|NP_003582.2| cullin 2 [Homo sapiens] >gnl|BL_ORD... 295 3e-78
gi|19577357|emb|CAD28438.1| putative scf complex protein [Asperg... 295 3e-78
gi|1923243|gb|AAC51190.1| CUL-2 [Homo sapiens] 295 3e-78
gi|34876224|ref|XP_341543.1| similar to Cul2 protein [Rattus nor... 294 6e-78
gi|49086180|ref|XP_405156.1| conserved hypothetical protein [Asp... 293 1e-77
gi|3360457|gb|AAC28621.1| cul-3 [Homo sapiens] 292 2e-77
gi|49083854|ref|XP_404174.1| hypothetical protein AN0037.2 [Aspe... 292 2e-77
gi|38257755|sp|Q9D4H8|CUL2_MOUSE Cullin homolog 2 (CUL-2) >gnl|B... 292 3e-77
gi|7498211|pir||T20365 hypothetical protein D2045.6 - Caenorhabd... 291 5e-77
gi|17552768|ref|NP_499309.1| cullin, a negative cell cycle regul... 291 5e-77
gi|46122285|ref|XP_385696.1| hypothetical protein FG05520.1 [Gib... 290 8e-77
gi|46440433|gb|EAK99739.1| hypothetical protein CaO19.7497 [Cand... 289 2e-76
gi|1381148|gb|AAC50547.1| Hs-CUL-4A 287 9e-76
gi|50733451|ref|XP_418878.1| PREDICTED: similar to Cullin homolo... 287 9e-76
gi|1381144|gb|AAC50545.1| Hs-CUL-2 286 2e-75
gi|1146334|gb|AAA85085.1| lin19 protein 283 1e-74
gi|17647593|ref|NP_523655.1| CG1877-PD [Drosophila melanogaster]... 283 2e-74
gi|11359308|pir||T43398 SCF complex protein cul-1 - fission yeas... 282 2e-74
gi|13172230|gb|AAK14056.1| SCF complex protein cul-1 homolog [Em... 281 4e-74
gi|22329305|ref|NP_171797.2| cullin family protein [Arabidopsis ... 280 8e-74
gi|19115171|ref|NP_594259.1| pcu1 [Schizosaccharomyces pombe] >g... 280 1e-73
gi|39580485|emb|CAE70455.1| Hypothetical protein CBG17038 [Caeno... 280 1e-73
gi|48098335|ref|XP_394044.1| similar to Cullin homolog 1 (CUL-1)... 279 2e-73
gi|39591886|emb|CAE71464.1| Hypothetical protein CBG18382 [Caeno... 278 5e-73
gi|38099188|gb|EAA46566.1| hypothetical protein MG08909.4 [Magna... 276 2e-72
gi|32403490|ref|XP_322358.1| hypothetical protein [Neurospora cr... 275 5e-72
gi|7484879|pir||T01092 cullin-like protein T10P11.14.1 - Arabido... 270 1e-70
gi|49068826|ref|XP_398702.1| hypothetical protein UM01087.1 [Ust... 268 6e-70
gi|4887184|gb|AAD32222.1| CulB [Dictyostelium discoideum] 266 2e-69
gi|31224586|ref|XP_317457.1| ENSANGP00000011859 [Anopheles gambi... 263 1e-68
gi|49078958|ref|XP_403178.1| hypothetical protein UM05563.1 [Ust... 263 2e-68
gi|31208797|ref|XP_313365.1| ENSANGP00000011815 [Anopheles gambi... 262 2e-68
gi|50550551|ref|XP_502748.1| hypothetical protein [Yarrowia lipo... 261 5e-68
gi|19484151|gb|AAH25902.1| Cul2 protein [Mus musculus] 260 9e-68
gi|41393511|gb|AAS02034.1| unknown [Homo sapiens] 260 1e-67
gi|50419313|ref|XP_458181.1| unnamed protein product [Debaryomyc... 258 3e-67
gi|1381140|gb|AAC47123.1| CUL-4 256 2e-66
gi|32563753|ref|NP_495525.2| cullin (96.5 kD) (cul-4) [Caenorhab... 256 2e-66
gi|50287829|ref|XP_446344.1| unnamed protein product [Candida gl... 254 6e-66
gi|49074814|ref|XP_401514.1| hypothetical protein UM03899.1 [Ust... 252 3e-65
gi|17539492|ref|NP_502412.1| cullin (cul-6) [Caenorhabditis eleg... 249 2e-64
gi|32700085|sp|Q17390|CUL2_CAEEL Cullin 2 249 3e-64
gi|25815093|emb|CAB07302.3| C. elegans CUL-2 protein (correspond... 246 2e-63
gi|25815091|emb|CAB70188.2| C. elegans CUL-2 protein (correspond... 246 2e-63
gi|25815092|emb|CAD18893.2| C. elegans CUL-2 protein (correspond... 246 2e-63
gi|50254537|gb|EAL17286.1| hypothetical protein CNBN1130 [Crypto... 245 3e-63
gi|39580486|emb|CAE70456.1| Hypothetical protein CBG17039 [Caeno... 244 9e-63
gi|39582341|emb|CAE67590.1| Hypothetical protein CBG13132 [Caeno... 239 2e-61
gi|47225141|emb|CAF98768.1| unnamed protein product [Tetraodon n... 238 4e-61
gi|19921636|ref|NP_610117.1| CG1512-PB [Drosophila melanogaster]... 238 6e-61
gi|7503458|pir||T16367 hypothetical protein F45E12.3 - Caenorhab... 237 8e-61
gi|38422757|emb|CAD45612.3| Hypothetical protein ZK520.4d [Caeno... 237 8e-61
gi|1381136|gb|AAC47121.1| CUL-2 237 1e-60
gi|25150754|ref|NP_499825.2| cullin (86.0 kD) (cul-2) [Caenorhab... 237 1e-60
gi|50732297|ref|XP_418568.1| PREDICTED: similar to cullin 2 [Gal... 236 1e-60
gi|50421217|ref|XP_459154.1| unnamed protein product [Debaryomyc... 236 2e-60
gi|22832829|gb|AAH34318.1| CUL1 protein [Homo sapiens] 235 3e-60
gi|19482162|ref|NP_083678.1| cullin 2 [Mus musculus] >gnl|BL_ORD... 233 2e-59
gi|50730518|ref|XP_416943.1| PREDICTED: similar to cullin 4A [Ga... 230 1e-58
gi|19115107|ref|NP_594195.1| cullin homolog [Schizosaccharomyces... 229 2e-58
gi|21466062|pdb|1LDK|B Chain B, Structure Of The Cul1-Rbx1-Skp1-... 225 4e-57
gi|46443555|gb|EAL02836.1| hypothetical protein CaO19.9243 [Cand... 221 8e-56
gi|34481803|emb|CAC87837.1| cullin 1C [Nicotiana tabacum] 220 1e-55
gi|7511184|pir||T27884 hypothetical protein ZK520.4 - Caenorhabd... 217 1e-54
gi|25395971|pir||C88618 protein ZK520.4 [imported] - Caenorhabdi... 217 1e-54
gi|39591800|emb|CAE71378.1| Hypothetical protein CBG18282 [Caeno... 213 1e-53
gi|1381150|gb|AAC50548.1| Hs-CUL-4B 211 6e-53
gi|12083629|ref|NP_073174.1| vasopressin-activated calcium-mobil... 208 5e-52
gi|16307595|gb|AAH10347.1| Cul4b protein [Mus musculus] 206 2e-51
gi|40254446|ref|NP_003469.2| Vasopressin-activated calcium-mobil... 206 3e-51
gi|47211879|emb|CAF91175.1| unnamed protein product [Tetraodon n... 204 6e-51
gi|26327761|dbj|BAC27621.1| unnamed protein product [Mus musculus] 204 8e-51
gi|50257187|gb|EAL19900.1| hypothetical protein CNBG0430 [Crypto... 203 1e-50
gi|28076981|ref|NP_082083.1| cullin 5; vasopressin-activated cal... 203 1e-50
gi|1628415|emb|CAA57465.1| vasopressin activated calcium mobiliz... 203 2e-50
gi|2394274|gb|AAB70253.1| vasopressin-activated calcium mobilizi... 202 3e-50
gi|1098008|prf||2115187A Ca-mobilizing receptor VACM-1 201 5e-50
gi|2493912|sp|Q29425|CUL5_RABIT Cullin homolog 5 (CUL-5) (Vasopr... 201 7e-50
gi|50306105|ref|XP_453014.1| unnamed protein product [Kluyveromy... 201 8e-50
gi|45187979|ref|NP_984202.1| ADR106Wp [Eremothecium gossypii] >g... 198 4e-49
gi|39593279|emb|CAE64749.1| Hypothetical protein CBG09538 [Caeno... 196 2e-48
gi|6321440|ref|NP_011517.1| Ubiquitin-protein ligase, member of ... 194 8e-48
gi|24650935|ref|NP_651665.2| CG1401-PA [Drosophila melanogaster]... 194 8e-48
gi|6320070|ref|NP_010150.1| Cullin, structural protein of SCF co... 193 1e-47
gi|31207163|ref|XP_312548.1| ENSANGP00000014259 [Anopheles gambi... 193 2e-47
gi|47191250|emb|CAF91922.1| unnamed protein product [Tetraodon n... 191 7e-47
gi|17946170|gb|AAL49126.1| RE55959p [Drosophila melanogaster] 190 1e-46
gi|48098182|ref|XP_394003.1| similar to ENSANGP00000011815 [Apis... 187 7e-46
gi|50731095|ref|XP_417163.1| PREDICTED: similar to Cullin homolo... 187 1e-45
gi|50310617|ref|XP_455328.1| unnamed protein product [Kluyveromy... 187 1e-45
gi|31224592|ref|XP_317458.1| ENSANGP00000023620 [Anopheles gambi... 184 1e-44
gi|39584626|emb|CAE72379.1| Hypothetical protein CBG19533 [Caeno... 182 3e-44
gi|17559070|ref|NP_505616.1| cullin (cul-5) [Caenorhabditis eleg... 177 1e-42
gi|50291355|ref|XP_448110.1| unnamed protein product [Candida gl... 170 1e-40
gi|11359037|pir||T43406 cullin-3 - fission yeast (Schizosaccharo... 170 1e-40
gi|45199016|ref|NP_986045.1| AFR498Wp [Eremothecium gossypii] >g... 168 6e-40
gi|50543028|ref|XP_499680.1| hypothetical protein [Yarrowia lipo... 152 3e-35
gi|46226834|gb|EAK87800.1| cullin-like protein of probable plant... 150 2e-34
gi|12837964|dbj|BAB24020.1| unnamed protein product [Mus musculus] 140 2e-31
gi|26332879|dbj|BAC30157.1| unnamed protein product [Mus musculus] 132 3e-29
gi|26450880|dbj|BAC42547.1| unknown protein [Arabidopsis thalian... 131 6e-29
gi|47206920|emb|CAF92555.1| unnamed protein product [Tetraodon n... 131 8e-29
gi|21070316|gb|AAM34251.1| cullin 4A [Equus caballus] 130 1e-28
gi|6651015|gb|AAF22129.1| cullin-like protein [Strongyloides ste... 127 9e-28
gi|37926500|pdb|1IUY|A Chain A, Solution Structure Of The Cullin... 127 2e-27
gi|12834824|dbj|BAB23057.1| unnamed protein product [Mus musculus] 126 2e-27
gi|47202555|emb|CAF87432.1| unnamed protein product [Tetraodon n... 126 3e-27
gi|12834494|dbj|BAB22933.1| unnamed protein product [Mus musculus] 126 3e-27
gi|47086627|ref|NP_997871.1| Vasopressin-activated calcium-mobil... 124 8e-27
gi|23612907|ref|NP_704446.1| cullin-like protein, putative [Plas... 122 4e-26
gi|47197064|emb|CAF94781.1| unnamed protein product [Tetraodon n... 117 1e-24
gi|50730516|ref|XP_416942.1| PREDICTED: similar to cullin 4A [Ga... 114 1e-23
gi|50419045|ref|XP_458044.1| unnamed protein product [Debaryomyc... 106 3e-21
gi|23485529|gb|EAA20460.1| hypothetical protein [Plasmodium yoel... 102 5e-20
gi|15218911|ref|NP_176188.1| cullin-related [Arabidopsis thaliana] 97 2e-18
gi|23489725|gb|EAA21664.1| cul-3 protein [Plasmodium yoelii yoelii] 96 4e-18
gi|21355929|ref|NP_648620.1| CG11261-PA [Drosophila melanogaster... 93 2e-17
gi|31194953|ref|XP_306424.1| ENSANGP00000001728 [Anopheles gambi... 92 7e-17
gi|15218925|ref|NP_176189.1| cullin-related [Arabidopsis thaliana] 86 3e-15
gi|47189496|emb|CAF93716.1| unnamed protein product [Tetraodon n... 86 4e-15
gi|34910384|ref|NP_916539.1| cullin-like protein [Oryza sativa (... 83 3e-14
gi|46228145|gb|EAK89044.1| cullin domain containing protein [Cry... 80 3e-13
gi|15451283|dbj|BAB64445.1| hypothetical protein [Macaca fascicu... 79 6e-13
gi|10241616|emb|CAC09456.1| putative cullin 3 protein [Oryza sat... 79 6e-13
gi|26348465|dbj|BAC37872.1| unnamed protein product [Mus musculus] 77 2e-12
gi|25404232|pir||A96622 hypothetical protein F23H11.12 [imported... 74 1e-11
gi|23612375|ref|NP_703955.1| cullin-like protein, putative [Plas... 74 1e-11
gi|15234414|ref|NP_192947.1| expressed protein [Arabidopsis thal... 70 2e-10
gi|38347323|emb|CAE05973.2| OSJNBa0063C18.14 [Oryza sativa (japo... 69 7e-10
gi|34481805|emb|CAC87838.1| cullin 1D [Nicotiana tabacum] 67 1e-09
gi|21314576|gb|AAM47013.1| cullin 4B [Equus caballus] 67 2e-09
gi|26326291|dbj|BAC26889.1| unnamed protein product [Mus musculus] 65 9e-09
gi|29841104|gb|AAP06117.1| similar to GenBank Accession Number A... 62 6e-08
gi|46440229|gb|EAK99537.1| hypothetical protein CaO19.2440 [Cand... 55 1e-05
gi|49533765|gb|AAT66764.1| putative anaphase promoting complex p... 51 1e-04
gi|26451938|dbj|BAC43061.1| unknown protein [Arabidopsis thaliana] 51 1e-04
gi|30678127|ref|NP_178543.2| E3 ubiquitin ligase, putative [Arab... 51 1e-04
gi|38077778|ref|XP_143141.3| similar to cullin 2 [Mus musculus] 49 4e-04
gi|47216548|emb|CAG04726.1| unnamed protein product [Tetraodon n... 49 7e-04
gi|6473961|dbj|BAA87201.1| Hypothetical nuclear protein [Schizos... 49 7e-04
gi|1122247|emb|CAA63850.1| a1 [Coccidioides immitis] 48 0.001
gi|31209907|ref|XP_313920.1| ENSANGP00000021886 [Anopheles gambi... 47 0.003
gi|630679|pir||S44845 K06H7.5 protein - Caenorhabditis elegans 44 0.013
gi|17554086|ref|NP_498762.1| putative cytoplasmic protein, with ... 44 0.013
gi|46108328|ref|XP_381222.1| hypothetical protein FG01046.1 [Gib... 44 0.017
gi|50749857|ref|XP_421786.1| PREDICTED: similar to hypothetical ... 41 0.11
gi|50757486|ref|XP_415533.1| PREDICTED: similar to Anaphase prom... 41 0.15
gi|20130331|ref|NP_611862.1| CG3060-PA [Drosophila melanogaster]... 40 0.19
gi|21757588|dbj|BAC05153.1| unnamed protein product [Homo sapiens] 40 0.19
gi|47222359|emb|CAG05108.1| unnamed protein product [Tetraodon n... 40 0.19
gi|24429578|ref|NP_722517.1| chromosome 10 open reading frame 46... 40 0.19
gi|28460532|emb|CAD67614.1| hypothetical protein [Homo sapiens] 40 0.19
gi|16198245|gb|AAL13946.1| LD45730p [Drosophila melanogaster] 40 0.19
gi|15342006|gb|AAH13270.1| 2700078E11Rik protein [Mus musculus] 40 0.25
gi|20890556|ref|XP_129335.1| RIKEN cDNA 2700078E11 [Mus musculus... 40 0.25
gi|34864857|ref|XP_345053.1| similar to 2700078E11Rik protein [R... 40 0.25
gi|12859308|dbj|BAB31607.1| unnamed protein product [Mus musculus] 40 0.25
gi|7243193|dbj|BAA92644.1| KIAA1406 protein [Homo sapiens] 39 0.73
gi|39583271|emb|CAE60063.1| Hypothetical protein CBG03579 [Caeno... 39 0.73
gi|16306777|gb|AAH01579.1| ANAPC2 protein [Homo sapiens] 39 0.73
gi|7019327|ref|NP_037498.1| anaphase-promoting complex subunit 2... 39 0.73
gi|20071060|gb|AAH27351.1| Anapc2 protein [Mus musculus] 38 1.2
gi|22477982|gb|AAH37054.1| Cul5 protein [Mus musculus] 38 1.2
gi|34852993|ref|XP_215994.2| similar to anaphase-promoting compl... 38 1.2
gi|37360366|dbj|BAC98161.1| mKIAA1406 protein [Mus musculus] 38 1.2
gi|30424970|ref|NP_780509.1| anaphase-promoting complex subunit ... 38 1.2
gi|38345340|emb|CAE03151.2| OSJNBa0081L15.13 [Oryza sativa (japo... 38 1.2
gi|46143721|ref|ZP_00134569.2| COG3006: Uncharacterized protein ... 37 1.6
gi|38104390|gb|EAA50965.1| hypothetical protein MG04724.4 [Magna... 37 1.6
gi|41350157|gb|AAS00419.1| ObsA [Saccharopolyspora spinosa] 37 1.6
gi|6323102|ref|NP_013174.1| Hypothetical ORF; Ylr073cp [Saccharo... 37 2.1
gi|18402837|ref|NP_565733.1| DNA repair-recombination protein (R... 37 2.1
gi|25301664|pir||D84727 probable RAD50 DNA repair protein [impor... 37 2.8
gi|6323115|ref|NP_013187.1| Subunit of the condensin complex, wh... 37 2.8
gi|32408421|ref|XP_324692.1| hypothetical protein [Neurospora cr... 37 2.8
gi|19921500|ref|NP_609909.1| CG17324-PA [Drosophila melanogaster... 37 2.8
gi|2204269|emb|CAA97648.1| unnamed protein product [Saccharomyce... 37 2.8
gi|23509602|ref|NP_702269.1| hypothetical protein [Plasmodium fa... 36 3.6
gi|45524433|ref|ZP_00175717.1| COG1541: Coenzyme F390 synthetase... 36 3.6
gi|6473935|dbj|BAA87197.1| Hypothetical nuclear protein [Schizos... 36 3.6
gi|47208417|emb|CAF92198.1| unnamed protein product [Tetraodon n... 36 4.7
gi|42560864|ref|NP_975315.1| Conserved hypothetical transmembran... 36 4.7
gi|23510196|ref|NP_702862.1| hypothetical protein [Plasmodium fa... 36 4.7
gi|47226267|emb|CAG09235.1| unnamed protein product [Tetraodon n... 36 4.7
gi|33152623|ref|NP_873976.1| MukF protein [Haemophilus ducreyi 3... 35 6.2
gi|32472966|ref|NP_865960.1| hypothetical protein-transmembrane ... 35 6.2
gi|50748800|ref|XP_421410.1| PREDICTED: similar to NUANCE [Gallu... 35 6.2
gi|49088956|ref|XP_406246.1| hypothetical protein AN2109.2 [Aspe... 35 6.2
gi|22549540|ref|NP_689313.1| bJDP-like protein [Mamestra configu... 35 6.2
gi|23485476|gb|EAA20445.1| hypothetical protein [Plasmodium yoel... 35 6.2
gi|48140126|ref|XP_397083.1| similar to CG1133-PA [Apis mellifera] 35 6.2
gi|15792664|ref|NP_282487.1| hypothetical protein Cj1341c (1318 ... 35 8.1
gi|23491217|gb|EAA22808.1| hypothetical protein [Plasmodium yoel... 35 8.1
gi|50738613|ref|XP_419326.1| PREDICTED: similar to p53-associate... 35 8.1
gi|15234086|ref|NP_192027.1| XH/XS domain-containing protein [Ar... 35 8.1
gi|24641414|ref|NP_572750.2| CG32662-PA [Drosophila melanogaster... 35 8.1
>gi|17566422|ref|NP_503151.1| cullin (90.2 kD) (cul-3) [Caenorhabditis
elegans]
gi|32172452|sp|Q17391|CUL3_CAEEL Cullin 3
gi|14670190|gb|AAK72067.1| Cullin protein 3 [Caenorhabditis elegans]
Length = 777
Score = 1511 bits (3912), Expect = 0.0
Identities = 762/777 (98%), Positives = 762/777 (98%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 60
Query: 181 MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDIL 360
MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDIL
Sbjct: 61 MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDIL 120
Query: 361 MYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHG 540
MYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHG
Sbjct: 121 MYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHG 180
Query: 541 IKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAM 720
IKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAM
Sbjct: 181 IKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAM 240
Query: 721 HDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFR 900
HDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFR
Sbjct: 241 HDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFR 300
Query: 901 IFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSS 1080
IFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSS
Sbjct: 301 IFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSS 360
Query: 1081 LLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDN 1260
LLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDN
Sbjct: 361 LLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDN 420
Query: 1261 VMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMF 1440
VMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMF
Sbjct: 421 VMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMF 480
Query: 1441 RDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT 1620
RDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT
Sbjct: 481 RDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT 540
Query: 1621 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKI 1800
QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASM MKERKPEHKI
Sbjct: 541 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSSSGESMKERKPEHKI 600
Query: 1801 LQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGK 1980
LQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGK
Sbjct: 601 LQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGK 660
Query: 1981 DAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIM 2160
DAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIM
Sbjct: 661 DAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIM 720
Query: 2161 KARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
KARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA
Sbjct: 721 KARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 777
>gi|1381138|gb|AAC47122.1| CUL-3
Length = 780
Score = 1503 bits (3891), Expect = 0.0
Identities = 761/780 (97%), Positives = 761/780 (97%), Gaps = 3/780 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 60
Query: 181 MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDIL 360
MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDIL
Sbjct: 61 MVLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDIL 120
Query: 361 MYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHG 540
MYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHG
Sbjct: 121 MYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHG 180
Query: 541 IKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAM 720
IKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAM
Sbjct: 181 IKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAM 240
Query: 721 HDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFR 900
HDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFR
Sbjct: 241 HDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFR 300
Query: 901 IFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSS 1080
IFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSS
Sbjct: 301 IFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSS 360
Query: 1081 LLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDN 1260
LLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDN
Sbjct: 361 LLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDN 420
Query: 1261 VMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMF 1440
VMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMF
Sbjct: 421 VMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMF 480
Query: 1441 RDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT 1620
RDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT
Sbjct: 481 RDKELWLTLATSFRDWREAQPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT 540
Query: 1621 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKI 1800
QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASM MKERKPEHKI
Sbjct: 541 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMSNEENGPGPSGSGESMKERKPEHKI 600
Query: 1801 LQVNTHQMIILLQFNHHNRISC---QQLMDELKIPERELKRNLQSLALGKASQRILVRKN 1971
LQVNTHQMIILLQ NHHNRISC QQLMDELKIPERELKRNLQSLALGKASQRILVRKN
Sbjct: 601 LQVNTHQMIILLQLNHHNRISCQHEQQLMDELKIPERELKRNLQSLALGKASQRILVRKN 660
Query: 1972 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIV 2151
KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIV
Sbjct: 661 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIV 720
Query: 2152 RIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
RIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA
Sbjct: 721 RIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 780
>gi|39592741|emb|CAE62355.1| Hypothetical protein CBG06434
[Caenorhabditis briggsae]
Length = 778
Score = 1292 bits (3343), Expect = 0.0
Identities = 650/778 (83%), Positives = 701/778 (89%), Gaps = 2/778 (0%)
Frame = +1
Query: 4 SGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTM 183
+G G GGQQKMRIRPFM T+DEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTM
Sbjct: 1 NGGGGGGGQQKMRIRPFMTTVDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTM 60
Query: 184 VLHKHGERLYNGLKDVIQDHMASVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILM 363
VLHKHGERLYNGL++VIQ+HM VR+RIIESM+SG FLET+AE+W DHTVAMVMIRDILM
Sbjct: 61 VLHKHGERLYNGLREVIQEHMEVVRVRIIESMDSGVFLETMAEAWNDHTVAMVMIRDILM 120
Query: 364 YMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGI 543
YMDRIYVAQN VL VYNLGL+++RTEILR NGIGDR+RD+LLELIK DRKSNQINWHGI
Sbjct: 121 YMDRIYVAQNPSVLQVYNLGLESFRTEILRNNGIGDRLRDSLLELIKSDRKSNQINWHGI 180
Query: 544 KNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMH 723
KNAC+ML+SLGID+R VYE+EFE+PLLKET +YYR+VC+ L+G+NDACFYL QVE A+H
Sbjct: 181 KNACEMLVSLGIDNRKVYEEEFEKPLLKETCEYYREVCETLLAGENDACFYLEQVETAIH 240
Query: 724 DEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRI 903
DEA+RASRYLDK TE KILQVMDDVMVA H+ TIVYM NGGVKFML+HK++EDLTRIFRI
Sbjct: 241 DEANRASRYLDKETEVKILQVMDDVMVANHMSTIVYMPNGGVKFMLQHKRVEDLTRIFRI 300
Query: 904 FKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSL 1083
FKRI +S VP GLK LLKAVSEYL ETG+NIVKNEDLLK PV FVNELLQLKDYFSSL
Sbjct: 301 FKRITESPAVPVSGLKVLLKAVSEYLTETGTNIVKNEDLLKAPVQFVNELLQLKDYFSSL 360
Query: 1084 LTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNV 1263
LTTAF DDR+FKNRFQHDFETFLNSNRQSPEFVA YMDDMLRSGLKCVSDAEMDNKLDNV
Sbjct: 361 LTTAFGDDREFKNRFQHDFETFLNSNRQSPEFVAHYMDDMLRSGLKCVSDAEMDNKLDNV 420
Query: 1264 MILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFR 1443
MILFRYLQEKDVFEKYFKQYLAKRLLLDKS SDDVEKALLAKLKTECGCQFTQ+LENMFR
Sbjct: 421 MILFRYLQEKDVFEKYFKQYLAKRLLLDKSSSDDVEKALLAKLKTECGCQFTQRLENMFR 480
Query: 1444 DKELWLTLATSFRDWREA-QPTKMSIDISLRVLTAGVWPTVQCNPVVLPQELSVAYEMFT 1620
DKELWL LA SFRDWRE Q K+++DISLRVLTAGVWPTVQC PVVLPQEL++AY+MFT
Sbjct: 481 DKELWLNLANSFRDWREGPQGHKLTMDISLRVLTAGVWPTVQCTPVVLPQELALAYDMFT 540
Query: 1621 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKI 1800
+YTEKHTGRKLTINTLLGNADVKATFYPPPKAS KERKPE+KI
Sbjct: 541 AFYTEKHTGRKLTINTLLGNADVKATFYPPPKASQSNEENGPGPSNAGGEPKERKPENKI 600
Query: 1801 LQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKN-KG 1977
LQV THQMIILLQFNH ISCQQL+D+LKIPE+ELKR LQSLAL K+SQRIL RK KG
Sbjct: 601 LQVTTHQMIILLQFNHRKVISCQQLLDDLKIPEKELKRCLQSLALSKSSQRILNRKGPKG 660
Query: 1978 KDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRI 2157
+D IDMSDEF VNDNFQSKLTRVKVQMV+GKVESEPEI+ETRQKVEDDRKLEVEAAIVRI
Sbjct: 661 RDMIDMSDEFIVNDNFQSKLTRVKVQMVSGKVESEPEIKETRQKVEDDRKLEVEAAIVRI 720
Query: 2158 MKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
MKARK+LNHNNLV EVTQQLRHRFMPSP IIKQRIETLIEREYL RDE DHR+Y YIA
Sbjct: 721 MKARKRLNHNNLVTEVTQQLRHRFMPSPTIIKQRIETLIEREYLQRDEQDHRSYSYIA 778
>gi|34876967|ref|XP_217454.2| similar to cullin 3 [Rattus norvegicus]
Length = 768
Score = 712 bits (1839), Expect = 0.0
Identities = 376/781 (48%), Positives = 533/781 (68%), Gaps = 4/781 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 4 LSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 63
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDI
Sbjct: 64 MVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDI 122
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWH 537
LMYMDR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++
Sbjct: 123 LMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRG 181
Query: 538 GIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIA 717
I+NAC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE
Sbjct: 182 AIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEAR 240
Query: 718 MHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIF 897
+++E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++
Sbjct: 241 INEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMY 300
Query: 898 RIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFS 1077
++F R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F
Sbjct: 301 KLFSRVPN-------GLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFD 353
Query: 1078 SLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLD 1257
L +F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++ LD
Sbjct: 354 RFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILD 413
Query: 1258 NVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENM 1437
M+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE M
Sbjct: 414 KAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGM 473
Query: 1438 FRDKELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYE 1611
FRD + T FR +A + +D+++RVLT G WPT P +P A+E
Sbjct: 474 FRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFE 533
Query: 1612 MFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPE 1791
+F ++Y KH+GR+LT+ +G+AD+ ATFY P K ++
Sbjct: 534 IFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH--- 590
Query: 1792 HKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKN 1971
ILQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++
Sbjct: 591 --ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEP 648
Query: 1972 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAI 2148
K K+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAI
Sbjct: 649 KSKE-IESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAI 707
Query: 2149 VRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYI 2328
VRIMK+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+
Sbjct: 708 VRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYV 767
Query: 2329 A 2331
A
Sbjct: 768 A 768
>gi|40788303|dbj|BAA31592.2| KIAA0617 protein [Homo sapiens]
Length = 786
Score = 711 bits (1836), Expect = 0.0
Identities = 376/781 (48%), Positives = 533/781 (68%), Gaps = 4/781 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 22 LSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 81
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDI
Sbjct: 82 MVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDI 140
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWH 537
LMYMDR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++
Sbjct: 141 LMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRG 199
Query: 538 GIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIA 717
I+NAC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE
Sbjct: 200 AIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEAR 258
Query: 718 MHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIF 897
+++E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++
Sbjct: 259 INEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMY 318
Query: 898 RIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFS 1077
++F R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F
Sbjct: 319 KLFSRVPN-------GLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFD 371
Query: 1078 SLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLD 1257
L +F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++ LD
Sbjct: 372 RFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILD 431
Query: 1258 NVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENM 1437
M+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE M
Sbjct: 432 KAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGM 491
Query: 1438 FRDKELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYE 1611
FRD + T FR +A + +D+++RVLT G WPT P +P A+E
Sbjct: 492 FRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFE 551
Query: 1612 MFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPE 1791
+F ++Y KH+GR+LT+ +G+AD+ ATFY P K ++
Sbjct: 552 IFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH--- 608
Query: 1792 HKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKN 1971
ILQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++
Sbjct: 609 --ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEP 666
Query: 1972 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAI 2148
K K+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAI
Sbjct: 667 KSKE-IENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAI 725
Query: 2149 VRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYI 2328
VRIMK+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+
Sbjct: 726 VRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYV 785
Query: 2329 A 2331
A
Sbjct: 786 A 786
>gi|50418207|gb|AAH77239.1| Unknown (protein for MGC:79108) [Xenopus
laevis]
Length = 768
Score = 711 bits (1836), Expect = 0.0
Identities = 374/777 (48%), Positives = 533/777 (68%), Gaps = 4/777 (0%)
Frame = +1
Query: 13 SGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLH 192
+G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYTMVLH
Sbjct: 8 TGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLH 67
Query: 193 KHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYM 369
KHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDILMYM
Sbjct: 68 KHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYM 126
Query: 370 DRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKN 549
DR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++ I+N
Sbjct: 127 DRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRN 185
Query: 550 ACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDE 729
AC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE +++E
Sbjct: 186 ACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEARINEE 244
Query: 730 ASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFK 909
R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++++F
Sbjct: 245 IERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFS 304
Query: 910 RIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLT 1089
R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F L
Sbjct: 305 RVPN-------GLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQ 357
Query: 1090 TAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMI 1269
+F++DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E+++ LD M+
Sbjct: 358 ESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMV 417
Query: 1270 LFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDK 1449
LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE MFRD
Sbjct: 418 LFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDM 477
Query: 1450 ELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQ 1623
+ T FR + + +D+++RVLT G WPT P +P A+E+F +
Sbjct: 478 SISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRR 537
Query: 1624 YYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKIL 1803
+Y KH+GR+LT+ +G+AD+ ATFY P K ++ IL
Sbjct: 538 FYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH-----IL 592
Query: 1804 QVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKD 1983
QV+T QM IL+ FN+ ++ + +++ E IPEREL R LQSLA GK +QR+L ++ K K+
Sbjct: 593 QVSTFQMTILMLFNNRDKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKE 652
Query: 1984 AIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAIVRIM 2160
I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAIVRIM
Sbjct: 653 -IESGHMFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIM 711
Query: 2161 KARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
K+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+A
Sbjct: 712 KSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768
>gi|4503165|ref|NP_003581.1| cullin 3 [Homo sapiens]
gi|12643396|sp|Q13618|CUL3_HUMAN Cullin homolog 3 (CUL-3)
gi|3639052|gb|AAC36304.1| cullin 3 [Homo sapiens]
gi|24660078|gb|AAH39598.1| Cullin 3 [Homo sapiens]
Length = 768
Score = 711 bits (1836), Expect = 0.0
Identities = 376/781 (48%), Positives = 533/781 (68%), Gaps = 4/781 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 4 LSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 63
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDI
Sbjct: 64 MVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDI 122
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWH 537
LMYMDR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++
Sbjct: 123 LMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRG 181
Query: 538 GIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIA 717
I+NAC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE
Sbjct: 182 AIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEAR 240
Query: 718 MHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIF 897
+++E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++
Sbjct: 241 INEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMY 300
Query: 898 RIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFS 1077
++F R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F
Sbjct: 301 KLFSRVPN-------GLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFD 353
Query: 1078 SLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLD 1257
L +F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++ LD
Sbjct: 354 RFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILD 413
Query: 1258 NVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENM 1437
M+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE M
Sbjct: 414 KAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGM 473
Query: 1438 FRDKELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYE 1611
FRD + T FR +A + +D+++RVLT G WPT P +P A+E
Sbjct: 474 FRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFE 533
Query: 1612 MFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPE 1791
+F ++Y KH+GR+LT+ +G+AD+ ATFY P K ++
Sbjct: 534 IFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH--- 590
Query: 1792 HKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKN 1971
ILQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++
Sbjct: 591 --ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEP 648
Query: 1972 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAI 2148
K K+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAI
Sbjct: 649 KSKE-IENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAI 707
Query: 2149 VRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYI 2328
VRIMK+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+
Sbjct: 708 VRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYV 767
Query: 2329 A 2331
A
Sbjct: 768 A 768
>gi|39104526|dbj|BAC97984.2| mKIAA0617 protein [Mus musculus]
Length = 792
Score = 711 bits (1835), Expect = 0.0
Identities = 376/781 (48%), Positives = 533/781 (68%), Gaps = 4/781 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 28 LSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 87
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDI
Sbjct: 88 MVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDI 146
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWH 537
LMYMDR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++
Sbjct: 147 LMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRG 205
Query: 538 GIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIA 717
I+NAC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE
Sbjct: 206 AIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEAR 264
Query: 718 MHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIF 897
+++E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++
Sbjct: 265 INEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMY 324
Query: 898 RIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFS 1077
++F R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F
Sbjct: 325 KLFSRVPN-------GLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFD 377
Query: 1078 SLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLD 1257
L +F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++ LD
Sbjct: 378 RFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILD 437
Query: 1258 NVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENM 1437
M+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE M
Sbjct: 438 KAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGM 497
Query: 1438 FRDKELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYE 1611
FRD + T FR +A + +D+++RVLT G WPT P +P A+E
Sbjct: 498 FRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFE 557
Query: 1612 MFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPE 1791
+F ++Y KH+GR+LT+ +G+AD+ ATFY P K ++
Sbjct: 558 IFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH--- 614
Query: 1792 HKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKN 1971
ILQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++
Sbjct: 615 --ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEP 672
Query: 1972 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAI 2148
K K+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAI
Sbjct: 673 KSKE-IESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAI 731
Query: 2149 VRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYI 2328
VRIMK+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+
Sbjct: 732 VRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYV 791
Query: 2329 A 2331
A
Sbjct: 792 A 792
>gi|7710014|ref|NP_057925.1| cullin 3 [Mus musculus]
gi|13124074|sp|Q9JLV5|CUL3_MOUSE Cullin homolog 3 (CUL-3)
gi|7108617|gb|AAF36500.1| cullin 3 [Mus musculus]
gi|20071136|gb|AAH27304.1| Cullin 3 [Mus musculus]
Length = 768
Score = 711 bits (1835), Expect = 0.0
Identities = 376/781 (48%), Positives = 533/781 (68%), Gaps = 4/781 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 4 LSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 63
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDI
Sbjct: 64 MVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDI 122
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWH 537
LMYMDR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++
Sbjct: 123 LMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRG 181
Query: 538 GIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIA 717
I+NAC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE
Sbjct: 182 AIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEAR 240
Query: 718 MHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIF 897
+++E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++
Sbjct: 241 INEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMY 300
Query: 898 RIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFS 1077
++F R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F
Sbjct: 301 KLFSRVPN-------GLKTMCECMSCYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFD 353
Query: 1078 SLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLD 1257
L +F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++ LD
Sbjct: 354 RFLQESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILD 413
Query: 1258 NVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENM 1437
M+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE M
Sbjct: 414 KAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGM 473
Query: 1438 FRDKELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYE 1611
FRD + T FR +A + +D+++RVLT G WPT P +P A+E
Sbjct: 474 FRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFE 533
Query: 1612 MFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPE 1791
+F ++Y KH+GR+LT+ +G+AD+ ATFY P K ++
Sbjct: 534 IFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH--- 590
Query: 1792 HKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKN 1971
ILQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++
Sbjct: 591 --ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEP 648
Query: 1972 KGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAI 2148
K K+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAI
Sbjct: 649 KSKE-IESGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAI 707
Query: 2149 VRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYI 2328
VRIMK+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+
Sbjct: 708 VRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYV 767
Query: 2329 A 2331
A
Sbjct: 768 A 768
>gi|40807151|gb|AAH65357.1| Cullin 3 [Danio rerio]
Length = 766
Score = 708 bits (1828), Expect = 0.0
Identities = 375/778 (48%), Positives = 531/778 (68%), Gaps = 4/778 (0%)
Frame = +1
Query: 10 RSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVL 189
+ G KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYTMVL
Sbjct: 5 KPGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVL 64
Query: 190 HKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMY 366
HKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDILMY
Sbjct: 65 HKHGEKLYTGLREVVTEHLINKVREDVLHSLNN-NFLQTLNQAWNDHQTAMVMIRDILMY 123
Query: 367 MDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIK 546
MDR+YV QNN V VYNLGL +R +++R I D +R LL++I +R+ ++ I+
Sbjct: 124 MDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERRGEVVDRGAIR 182
Query: 547 NACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHD 726
NAC ML+ LG++ R+VYE++FE P L ++++++ + +L+ +N A Y+ +VE +++
Sbjct: 183 NACQMLMVLGLEGRSVYEEDFEIPFLDMSAEFFQMESQKFLA-ENSASVYIKKVEARINE 241
Query: 727 EASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIF 906
E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++++F
Sbjct: 242 EIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLF 301
Query: 907 KRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLL 1086
R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F L
Sbjct: 302 GRVPN-------GLKTMCECMSWYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFL 354
Query: 1087 TTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVM 1266
+F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E+++ LD M
Sbjct: 355 QESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAM 414
Query: 1267 ILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRD 1446
+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE MFRD
Sbjct: 415 VLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRD 474
Query: 1447 KELWLTLATSFR-DWREAQPTKMSIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFT 1620
+ T FR + +Q + +D+++RVLT G WPT P +P A+E+F
Sbjct: 475 MSISNTTMDEFRHHLQTSQVSLCGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFR 534
Query: 1621 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKI 1800
++Y KH+GR+LT+ +G+AD+ ATFY P K ++ I
Sbjct: 535 RFYLAKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSDVGVGGALLTGSNTRKH-----I 589
Query: 1801 LQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGK 1980
LQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++ K K
Sbjct: 590 LQVSTFQMTILMLFNNREKFTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSK 649
Query: 1981 DAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAIVRI 2157
+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAIVRI
Sbjct: 650 E-IESGHVFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI 708
Query: 2158 MKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
MK+RKK+ HN LVAEVTQQLR RF+PSP++IK+RIE LIEREYLAR D + Y Y+A
Sbjct: 709 MKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 766
>gi|41055488|ref|NP_955985.1| cullin 3 [Danio rerio]
gi|37682167|gb|AAQ98010.1| cullin 3 [Danio rerio]
Length = 766
Score = 708 bits (1828), Expect = 0.0
Identities = 376/778 (48%), Positives = 530/778 (67%), Gaps = 4/778 (0%)
Frame = +1
Query: 10 RSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVL 189
+ G KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYTMVL
Sbjct: 5 KPGTKKDTKMRIRAFPMTMDEKYVNNIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVL 64
Query: 190 HKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMY 366
HKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDILMY
Sbjct: 65 HKHGEKLYTGLREVVTEHLINKVREDVLHSLNN-NFLQTLNQAWNDHQTAMVMIRDILMY 123
Query: 367 MDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIK 546
MDR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++ I+
Sbjct: 124 MDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIR 182
Query: 547 NACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHD 726
NAC ML+ LG+ R+VYE++FE P L ++++++ + +L+ +N A Y+ +VE +++
Sbjct: 183 NACQMLMVLGLKGRSVYEEDFEIPFLDMSAEFFQMESQKFLA-ENSASVYIKKVEARINE 241
Query: 727 EASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIF 906
E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++++F
Sbjct: 242 EIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLF 301
Query: 907 KRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLL 1086
R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F L
Sbjct: 302 GRVPN-------GLKTMCECMSWYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFL 354
Query: 1087 TTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVM 1266
+F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E+++ LD M
Sbjct: 355 QESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAM 414
Query: 1267 ILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRD 1446
+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE MFRD
Sbjct: 415 VLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRD 474
Query: 1447 KELWLTLATSFR-DWREAQPTKMSIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFT 1620
+ T FR + +Q + +D+++RVLT G WPT P +P A+E+F
Sbjct: 475 MSISNTTMDEFRHHLQTSQVSLCGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEVFR 534
Query: 1621 QYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKI 1800
++Y KH+GR+LT+ +G+AD+ ATFY P K ++ I
Sbjct: 535 RFYLAKHSGRQLTLQHHMGSADLNATFYGPIKKEDGSDVGVGGALLTGSNTRKH-----I 589
Query: 1801 LQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGK 1980
LQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++ K K
Sbjct: 590 LQVSTFQMTILMLFNNREKFTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSK 649
Query: 1981 DAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAIVRI 2157
+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAIVRI
Sbjct: 650 E-IESGHVFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRI 708
Query: 2158 MKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
MK+RKK+ HN LVAEVTQQLR RF+PSP++IK+RIE LIEREYLAR D + Y Y+A
Sbjct: 709 MKSRKKMQHNVLVAEVTQQLRARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 766
>gi|49116945|gb|AAH73186.1| Unknown (protein for MGC:80402) [Xenopus
laevis]
Length = 768
Score = 708 bits (1828), Expect = 0.0
Identities = 373/777 (48%), Positives = 531/777 (68%), Gaps = 4/777 (0%)
Frame = +1
Query: 13 SGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLH 192
+G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYTMVLH
Sbjct: 8 TGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLH 67
Query: 193 KHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYM 369
KHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDILMYM
Sbjct: 68 KHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYM 126
Query: 370 DRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKN 549
DR+YV QNN V VYNLGL +R +++R I D +R LL++I +RK ++ I+N
Sbjct: 127 DRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRN 185
Query: 550 ACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDE 729
AC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE +++E
Sbjct: 186 ACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEARINEE 244
Query: 730 ASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFK 909
R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++++F
Sbjct: 245 IERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFS 304
Query: 910 RIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLT 1089
R+ + GLK + + +S YL E G +V E KNPV+++ LL LK F L
Sbjct: 305 RVPN-------GLKTMCECMSLYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQ 357
Query: 1090 TAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMI 1269
+F++DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E+++ LD M+
Sbjct: 358 ESFSNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVESILDKAMV 417
Query: 1270 LFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDK 1449
LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE MFRD
Sbjct: 418 LFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDM 477
Query: 1450 ELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQ 1623
+ T FR + + +D+++RVLT G WPT P +P A+E+F +
Sbjct: 478 SISNTTMDEFRQHLQTTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPSPRHAFEIFRR 537
Query: 1624 YYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKIL 1803
+Y KH+GR+LT+ +G+AD+ ATFY K ++ IL
Sbjct: 538 FYLAKHSGRQLTLQHHMGSADLNATFYGAVKKEDGSEVGVGGAQVTGSNTRKH-----IL 592
Query: 1804 QVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKD 1983
QV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++ K K+
Sbjct: 593 QVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKE 652
Query: 1984 AIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAIVRIM 2160
I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAIVRIM
Sbjct: 653 -IESGHMFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIM 711
Query: 2161 KARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
K+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+A
Sbjct: 712 KSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 768
>gi|31223774|ref|XP_317352.1| ENSANGP00000010476 [Anopheles gambiae]
gi|21300201|gb|EAA12346.1| ENSANGP00000010476 [Anopheles gambiae str.
PEST]
Length = 779
Score = 702 bits (1812), Expect = 0.0
Identities = 375/789 (47%), Positives = 523/789 (65%), Gaps = 12/789 (1%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
MS S + KMRIR F T+DE+YV W LLK AIQEIQ+KNNSGLSFEELYRNAYT
Sbjct: 1 MSRVSTQKKEGKMRIRAFPMTMDEKYVESIWSLLKNAIQEIQKKNNSGLSFEELYRNAYT 60
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGERLY+GLK+V+ H+ S VR ++ S N +FL+T+ + W DH +MVMIRDI
Sbjct: 61 MVLHKHGERLYSGLKEVVTHHLESKVREEVLRSFNC-NFLQTLNQCWNDHQTSMVMIRDI 119
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWH 537
LMYMDR+YV QN+ V VYNLGL+ +R +++R I D +R+ LL ++ +RK I+
Sbjct: 120 LMYMDRVYVQQND-VDNVYNLGLNIFRDQVVRYPRIRDHMRETLLNMVMCERKGEAIDHI 178
Query: 538 GIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIA 717
IKNAC ML+ LGI+ R VYE++FERP L +++ +Y+ + +L+ +N A Y+ +VE
Sbjct: 179 AIKNACQMLMVLGINQRWVYEEDFERPFLTQSAAFYKLESQKFLA-ENSASVYIRRVEAR 237
Query: 718 MHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIF 897
+ +EA RA YLD+ TE++I++V++D ++ +H++TIV M+N GV +ML++ K EDL +
Sbjct: 238 ITEEAERAKLYLDESTESRIVEVVEDELIKKHMRTIVEMENSGVVYMLQNTKTEDLACMH 297
Query: 898 RIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDL-LKNPVNFVNELLQLKDYF 1074
++F R+ GGLK + VS+ L G ++VK E+ NP+ FV LL LKD
Sbjct: 298 KLFSRVS-------GGLKTIADCVSQNLRSLGRDLVKEEENGSTNPITFVQNLLDLKDRS 350
Query: 1075 SSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKL 1254
L +F +D+ FKN DFE FLN N +SPE+++L++DD L+ G K +S+ E++ L
Sbjct: 351 DHFLYHSFNNDKTFKNMISSDFEHFLNLNSKSPEYLSLFIDDKLKKGCKGMSEQEIETIL 410
Query: 1255 DNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLEN 1434
D M+LFRYLQEKDVFE+Y+K +LAKRLLL+KS SDD EK +++KLKTECGCQFT KLE
Sbjct: 411 DKTMVLFRYLQEKDVFERYYKAHLAKRLLLNKSVSDDSEKNMISKLKTECGCQFTSKLEG 470
Query: 1435 MFRDKELWLTLATSFRDWREAQPTKMS-IDISLRVLTAGVWPTVQCNPVV-LPQELSVAY 1608
MF+D + T+ F++ + + +++++R+LT G WPT P +P A+
Sbjct: 471 MFKDMSVSNTVMEEFKNHINNDNSALEGVELTVRILTTGFWPTQSVTPNCNIPAAPRKAF 530
Query: 1609 EMFTQYYTEKHTGRKLTINTLLGNADVKATFY--------PPPKASMXXXXXXXXXXXXX 1764
E F ++Y KH+GR+LT+ LG + A FY S
Sbjct: 531 ETFKRFYLAKHSGRQLTLQPQLGTVYMNAEFYGVKAEKEKTEGNCSSTAPSAGSSSAPTG 590
Query: 1765 XXMKERKPEHKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKA 1944
P+ +LQ++T+QM +L+ FN+ R++ + + E IP ++L R LQSL++GK
Sbjct: 591 GAASLDAPKRHVLQLSTYQMCVLMLFNNRERMTYEDIQQETDIPSKDLIRALQSLSMGKQ 650
Query: 1945 SQRILVRKNKGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDR 2124
QR+LVR K I +DEF VND F SK +VK+Q V K ESEPE +ETR KV++DR
Sbjct: 651 QQRLLVRTPKTSKEIVSTDEFYVNDAFVSKFHKVKIQTVAAKGESEPERKETRSKVDEDR 710
Query: 2125 KLEVEAAIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEH 2304
K E+EAAIVRIMKARK++ HN LV++VT QL+ RF+PSP+IIK+RIE LIEREYLAR
Sbjct: 711 KHEIEAAIVRIMKARKRMPHNLLVSDVTSQLKSRFLPSPVIIKKRIEGLIEREYLARTPE 770
Query: 2305 DHRAYQYIA 2331
D + Y Y+A
Sbjct: 771 DRKIYVYLA 779
>gi|17737421|ref|NP_523573.1| CG11861-PA [Drosophila melanogaster]
gi|24584423|ref|NP_723907.1| CG11861-PB [Drosophila melanogaster]
gi|45550981|ref|NP_723908.2| CG11861-PC [Drosophila melanogaster]
gi|7287895|gb|AAF44933.1| symbol=gft; synonym=BG:DS07851.2;
cDNA=method:''sim4'', score:''1000.0'', desc:''LD10516 LD
Drosophila melanogaster embryo BlueScript Drosophila
melanogaster cDNA clone, full length mRNA sequence from
BDGP''; match=method:''BLASTX'', version:''2.0a19MP-WashU
[05-Feb-1998] [Build sol2.5-ultra 01:47:30
05-Feb-1998]'', score:''832.0'',
desc:''trEMBL::d1032553:KIAA0617 PROTEIN. organism:HOMO
SAPIENS (HUMAN). dbxref:GenBank; AB014517; d1032553;
-.'', species:''HOMO SAPIENS
gi|7298217|gb|AAF53450.1| CG11861-PA [Drosophila melanogaster]
gi|7298218|gb|AAF53451.1| CG11861-PB [Drosophila melanogaster]
gi|45445143|gb|AAN10895.2| CG11861-PC [Drosophila melanogaster]
Length = 773
Score = 696 bits (1797), Expect = 0.0
Identities = 371/774 (47%), Positives = 526/774 (67%), Gaps = 8/774 (1%)
Frame = +1
Query: 34 KMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLY 213
KMRIR F A++DE+YV W LK AIQEIQ+KNNSGLSFE+LYRNAY MVLHKHG RLY
Sbjct: 13 KMRIRAFPASMDEKYVETIWASLKNAIQEIQKKNNSGLSFEQLYRNAYNMVLHKHGNRLY 72
Query: 214 NGLKDVIQDHMA-SVRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQ 390
GL++V+ +H+ VR ++E+++S +FL + ++W DH +MVMIRDILMYMDR+YV Q
Sbjct: 73 YGLREVVSEHLEHKVRADVLEALHS-NFLPKLNQAWTDHQTSMVMIRDILMYMDRVYV-Q 130
Query: 391 NNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLIS 570
V VYNLGL +R +++R + I +R+ LL ++ +R IN IKNAC MLI+
Sbjct: 131 QREVDNVYNLGLILFRDQVVRYSEIQKALREKLLGMVMEERHGEAINHLAIKNACSMLIT 190
Query: 571 LGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRY 750
LGI+SRTVYE++FE+P L +++ +Y+ +N+L+ +N+A Y+ +VE + +E+SRA+ Y
Sbjct: 191 LGINSRTVYEEDFEKPFLAQSAAFYKFESQNFLA-ENNAGVYIKKVEARITEESSRAALY 249
Query: 751 LDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVT 930
LDK TE +I++V+++ ++ +H++ IV M+N GV +M+++ K EDL +++F R+ +
Sbjct: 250 LDKDTEPRIVRVVEEELIKKHMRPIVEMENSGVVYMIKNSKTEDLACTYKLFSRLKEE-- 307
Query: 931 VPGGGLKALLKAVSEYLNETGSNIVKNEDLLK-NPVNFVNELLQLKDYFSSLLTTAFADD 1107
GLK + +S YL E G +VK E+ NP+ FV LL LKD F L +FA+D
Sbjct: 308 ----GLKVIADTMSAYLREQGRMLVKEEENGNTNPITFVQNLLDLKDRFDQFLVHSFAND 363
Query: 1108 RDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQ 1287
R FKN DFE FLN N +SPE+++L++DD L+ G K +S+ E+++ LD M+LFR+L
Sbjct: 364 RIFKNVISSDFEHFLNLNNKSPEYLSLFIDDKLKKGGKGMSEQEIESILDKTMVLFRFLL 423
Query: 1288 EKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTL 1467
EKDVFE+Y+K +LAKRLLL+KS SDD EK +++KLKTECGCQFT KLE MF+D + T+
Sbjct: 424 EKDVFERYYKTHLAKRLLLNKSVSDDFEKNMISKLKTECGCQFTSKLEGMFKDMSVSNTI 483
Query: 1468 ATSFRDWREAQPTKM-SIDISLRVLTAGVWP----TVQCNPVVLPQELSVAYEMFTQYYT 1632
F+++ + +++++R+LT G WP T CN P+E A+++F +Y
Sbjct: 484 MDEFKNFVNNNNLSLGGVELTVRILTTGFWPTQTATPNCNIPAAPRE---AFDIFKNFYL 540
Query: 1633 EKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKILQVN 1812
KH+GR+LT+ +G A + A FY + +H ILQV+
Sbjct: 541 NKHSGRQLTLQPQMGTAYINAVFYGRKAVESEKDKDAPSSSSSGCGVPTTTRKH-ILQVS 599
Query: 1813 THQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDA-I 1989
T+QM +LL FN+ + ++ + E IPEREL R LQSL++GK +QR+LVR +K K I
Sbjct: 600 TYQMCVLLLFNNRDVLTYDDIHQETDIPERELVRALQSLSMGKPAQRLLVRNSKTKTKDI 659
Query: 1990 DMSDEFAVNDNFQSKLTRVKVQMVTGKVESEPEIRETRQKVEDDRKLEVEAAIVRIMKAR 2169
+ +DEF VND F SK RVK+Q V K ESEPE +ETR KV++DRK E+EAAIVRIMKAR
Sbjct: 660 EPTDEFYVNDAFNSKFHRVKIQTVAAKGESEPERKETRGKVDEDRKHEIEAAIVRIMKAR 719
Query: 2170 KKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
K+L HN LV++VT QL+ RF+PSP+ IK+RIE LIEREYL R D + Y Y+A
Sbjct: 720 KRLAHNLLVSDVTSQLKSRFLPSPVFIKKRIEGLIEREYLQRSPEDRKVYNYLA 773
>gi|33286088|gb|AAQ01660.1| cullin 3 isoform [Homo sapiens]
Length = 744
Score = 696 bits (1797), Expect = 0.0
Identities = 367/760 (48%), Positives = 520/760 (68%), Gaps = 4/760 (0%)
Frame = +1
Query: 64 IDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGERLYNGLKDVIQDH 243
+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYTMVLHKHGE+LY GL++V+ +H
Sbjct: 1 MDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYTMVLHKHGEKLYTGLREVVTEH 60
Query: 244 MAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVAQNNHVLPVYNL 420
+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDILMYMDR+YV QNN V VYNL
Sbjct: 61 LINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQQNN-VENVYNL 118
Query: 421 GLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLISLGIDSRTVYE 600
GL +R +++R I D +R LL++I +RK ++ I+NAC ML+ LG++ R+VYE
Sbjct: 119 GLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLMILGLEGRSVYE 178
Query: 601 DEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASRYLDKMTEAKIL 780
++FE P L+ ++++++ + +L+ +N A Y+ +VE +++E R LDK TE I+
Sbjct: 179 EDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEARINEEIERVMHCLDKSTEEPIV 237
Query: 781 QVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSVTVPGGGLKALL 960
+V++ ++++H++TIV M+N G+ ML++ K EDL ++++F R+ + GLK +
Sbjct: 238 KVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGCMYKLFSRVPN-------GLKTMC 290
Query: 961 KAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADDRDFKNRFQHDF 1140
+ +S YL E G +V E KNPV+++ LL LK F L +F +DR FK DF
Sbjct: 291 ECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLLESFNNDRLFKQTIAGDF 350
Query: 1141 ETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQEKDVFEKYFKQ 1320
E FLN N +SPE+++L++DD L G+K +++ E++ LD M+LFR++QEKDVFE+Y+KQ
Sbjct: 351 EYFLNLNSRSPEYLSLFIDDKLTKGVKGLTEQEVETILDKAMVLFRFMQEKDVFERYYKQ 410
Query: 1321 YLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTLATSFRDWREAQ 1500
+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE MFRD + T FR +A
Sbjct: 411 HLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISTTTMDEFRQHLQAT 470
Query: 1501 PTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQYYTEKHTGRKLTINTLL 1674
+ +D+++RVLT G WPT P +P A+E+F ++Y KH+GR+LT+ +
Sbjct: 471 GVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKHSGRQLTLQHHM 530
Query: 1675 GNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKILQVNTHQMIILLQFNHHN 1854
G+AD+ ATFY P K ++ ILQV+T QM IL+ FN+
Sbjct: 531 GSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH-----ILQVSTFQMTILMLFNNRE 585
Query: 1855 RISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSDEFAVNDNFQSK 2034
+ + +++ E IPEREL R LQSLA GK +QR+L ++ K K+ I+ F VND F SK
Sbjct: 586 KYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKE-IENGHIFTVNDQFISK 644
Query: 2035 LTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKLNHNNLVAEVTQ 2211
L RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAIVRIMK+RKK+ HN LVAEVTQ
Sbjct: 645 LHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKMQHNVLVAEVTQ 704
Query: 2212 QLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
QL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+A
Sbjct: 705 QLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 744
>gi|50752026|ref|XP_422620.1| PREDICTED: similar to mKIAA0617 protein
[Gallus gallus]
Length = 862
Score = 692 bits (1785), Expect = 0.0
Identities = 375/831 (45%), Positives = 533/831 (64%), Gaps = 54/831 (6%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 48 LSKGTGSRKDTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 107
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS------------------------------------ 252
MVLHKHGE+LY GL++V+ +H+ +
Sbjct: 108 MVLHKHGEKLYTGLREVVTEHLINKCDVEDDVLQYCIKLLVLTVWAAALPWPGPTCAYCQ 167
Query: 253 ---------------VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDILMYMDRIYVA 387
VR ++ S+N+ +FL+T+ ++W DH AMVMIRDILMYMDR+YV
Sbjct: 168 KRSLKLMGRTNQLKKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDILMYMDRVYVQ 226
Query: 388 QNNHVLPVYNLGLDAYRTEILRQNGIGDRIRDALLELIKLDRKSNQINWHGIKNACDMLI 567
QNN V VYNLGL +R +++R I D +R LL++I +RK ++ I+NAC ML+
Sbjct: 227 QNN-VENVYNLGLIIFRDQVVRYGCIRDHLRQTLLDMIARERKGEVVDRGAIRNACQMLM 285
Query: 568 SLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVEIAMHDEASRASR 747
LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE +++E R
Sbjct: 286 ILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVEARINEEIERVMH 344
Query: 748 YLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTRIFRIFKRIGDSV 927
LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL ++++F R+ +
Sbjct: 345 CLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLACMYKLFSRVPN-- 402
Query: 928 TVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDYFSSLLTTAFADD 1107
GLK + + +S YL E G +V E KNPV+++ LL LK F L +F +D
Sbjct: 403 -----GLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSRFDRFLQESFNND 457
Query: 1108 RDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNKLDNVMILFRYLQ 1287
R FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++ LD M+LFR++Q
Sbjct: 458 RLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETILDKAMVLFRFMQ 517
Query: 1288 EKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLENMFRDKELWLTL 1467
EKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE MFRD + T
Sbjct: 518 EKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLEGMFRDMSISNTT 577
Query: 1468 ATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVAYEMFTQYYTEKH 1641
FR ++ + +D+++RVLT G WPT P +P A+E+F ++Y KH
Sbjct: 578 MDEFRQHLQSTGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHAFEIFRRFYLAKH 637
Query: 1642 TGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERKPEHKILQVNTHQ 1821
+GR+LT+ +G+AD+ ATFY P K ++ ILQV+T Q
Sbjct: 638 SGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH-----ILQVSTFQ 692
Query: 1822 MIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVRKNKGKDAIDMSD 2001
M IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L ++ K K+ I+
Sbjct: 693 MTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTKEPKSKE-IENGH 751
Query: 2002 EFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEAAIVRIMKARKKL 2178
F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EAAIVRIMK+RKK+
Sbjct: 752 IFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEAAIVRIMKSRKKM 811
Query: 2179 NHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQYIA 2331
HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y Y+A
Sbjct: 812 QHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYTYVA 862
>gi|3139079|gb|AAC36682.1| cullin 3 [Homo sapiens]
Length = 768
Score = 689 bits (1779), Expect = 0.0
Identities = 372/783 (47%), Positives = 530/783 (67%), Gaps = 6/783 (0%)
Frame = +1
Query: 1 MSGRSGNGGQQKMRIRPFMATIDEQYVTQTWELLKRAIQEIQRKNNSGLSFEELYRNAYT 180
+S +G+ KMRIR F T+DE+YV W+LLK AIQEIQRKNNSGLSFEELYRNAYT
Sbjct: 4 LSKGTGSRKGTKMRIRAFPMTMDEKYVNSIWDLLKNAIQEIQRKNNSGLSFEELYRNAYT 63
Query: 181 MVLHKHGERLYNGLKDVIQDHMAS-VRIRIIESMNSGSFLETVAESWADHTVAMVMIRDI 357
MVLHKHGE+LY GL++V+ +H+ + VR ++ S+N+ +FL+T+ ++W DH AMVMIRDI
Sbjct: 64 MVLHKHGEKLYTGLREVVTEHLINKVREDVLNSLNN-NFLQTLNQAWNDHQTAMVMIRDI 122
Query: 358 LMYMDRIYVAQNNHVLPVYNLGLDAYRTEILRQNGI-GDRIRDAL-LELIKLDRKSNQIN 531
LMYMDR+YV QNN V VYNLGL +R +++R I G +++ + + +R+S
Sbjct: 123 LMYMDRVYVQQNN-VENVYNLGLIIFRDQVVRYGCIRGSSTANSIGYDCKRAERRSRSRG 181
Query: 532 WHGIKNACDMLISLGIDSRTVYEDEFERPLLKETSDYYRDVCKNWLSGDNDACFYLAQVE 711
I+NAC ML+ LG++ R+VYE++FE P L+ ++++++ + +L+ +N A Y+ +VE
Sbjct: 182 --AIRNACQMLMILGLEGRSVYEEDFEAPFLEMSAEFFQMESQKFLA-ENSASVYIKKVE 238
Query: 712 IAMHDEASRASRYLDKMTEAKILQVMDDVMVAEHIQTIVYMQNGGVKFMLEHKKIEDLTR 891
+++E R LDK TE I++V++ ++++H++TIV M+N G+ ML++ K EDL
Sbjct: 239 ARINEEIERVMHCLDKSTEEPIVKVVERELISKHMKTIVEMENSGLVHMLKNGKTEDLGC 298
Query: 892 IFRIFKRIGDSVTVPGGGLKALLKAVSEYLNETGSNIVKNEDLLKNPVNFVNELLQLKDY 1071
++++F R+ + GLK + + +S YL E G +V E KNPV+++ LL LK
Sbjct: 299 MYKLFSRVPN-------GLKTMCECMSSYLREQGKALVSEEGEGKNPVDYIQGLLDLKSR 351
Query: 1072 FSSLLTTAFADDRDFKNRFQHDFETFLNSNRQSPEFVALYMDDMLRSGLKCVSDAEMDNK 1251
F L +F +DR FK DFE FLN N +SPE+++L++DD L+ G+K +++ E++
Sbjct: 352 FDRFLLESFNNDRLFKQTIAGDFEYFLNLNSRSPEYLSLFIDDKLKKGVKGLTEQEVETI 411
Query: 1252 LDNVMILFRYLQEKDVFEKYFKQYLAKRLLLDKSCSDDVEKALLAKLKTECGCQFTQKLE 1431
LD M+LFR++QEKDVFE+Y+KQ+LA+RLL +KS SDD EK +++KLKTECGCQFT KLE
Sbjct: 412 LDKAMVLFRFMQEKDVFERYYKQHLARRLLTNKSVSDDSEKNMISKLKTECGCQFTSKLE 471
Query: 1432 NMFRDKELWLTLATSFRDWREAQPTKM-SIDISLRVLTAGVWPTVQCNPVV-LPQELSVA 1605
MFRD + T FR +A + +D+++RVLT G WPT P +P A
Sbjct: 472 GMFRDMSISNTTMDEFRQHLQATGVSLGGVDLTVRVLTTGYWPTQSATPKCNIPPAPRHA 531
Query: 1606 YEMFTQYYTEKHTGRKLTINTLLGNADVKATFYPPPKASMXXXXXXXXXXXXXXXMKERK 1785
+E+F ++Y KH+GR+LT+ +G+AD+ ATFY P K ++
Sbjct: 532 FEIFRRFYLAKHSGRQLTLQHHMGSADLNATFYGPVKKEDGSEVGVGGAQVTGSNTRKH- 590
Query: 1786 PEHKILQVNTHQMIILLQFNHHNRISCQQLMDELKIPERELKRNLQSLALGKASQRILVR 1965
ILQV+T QM IL+ FN+ + + +++ E IPEREL R LQSLA GK +QR+L +
Sbjct: 591 ----ILQVSTFQMTILMLFNNREKYTFEEIQQETDIPERELVRALQSLACGKPTQRVLTK 646
Query: 1966 KNKGKDAIDMSDEFAVNDNFQSKLTRVKVQMVTGKV-ESEPEIRETRQKVEDDRKLEVEA 2142
+ K K+ I+ F VND F SKL RVK+Q V K ES+PE +ETRQKV+DDRK E+EA
Sbjct: 647 EPKSKE-IENGHIFTVNDQFTSKLHRVKIQTVAAKQGESDPERKETRQKVDDDRKHEIEA 705
Query: 2143 AIVRIMKARKKLNHNNLVAEVTQQLRHRFMPSPIIIKQRIETLIEREYLARDEHDHRAYQ 2322
AIVRIMK+RKK+ HN LVAEVTQQL+ RF+PSP++IK+RIE LIEREYLAR D + Y
Sbjct: 706 AIVRIMKSRKKMQHNVLVAEVTQQLKARFLPSPVVIKKRIEGLIEREYLARTPEDRKVYT 765
Query: 2323 YIA 2331
Y+A
Sbjct: 766 YVA 768