Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= T01H8_4
(2223 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17508705|ref|NP_492320.1| ribosomal protein S6 kinase (rsk-1)... 1417 0.0
gi|17508707|ref|NP_492319.1| ribosomal protein S6 kinase (rsk-1)... 1404 0.0
gi|33300393|emb|CAB02301.2| Hypothetical protein T01H8.1b [Caeno... 1385 0.0
gi|45645188|sp|Q21734|KS6A_CAEEL Putative ribosomal protein S6 k... 1373 0.0
gi|33300395|emb|CAE17938.1| Hypothetical protein T01H8.1c [Caeno... 1371 0.0
gi|39595602|emb|CAE67103.1| Hypothetical protein CBG12516 [Caeno... 1283 0.0
gi|125692|sp|P18652|K6AA_CHICK Ribosomal protein S6 kinase II al... 862 0.0
gi|29294760|gb|AAH49076.1| Rps6ka1 protein [Mus musculus] 848 0.0
gi|50730201|ref|XP_416804.1| PREDICTED: similar to ribosomal pro... 847 0.0
gi|47086473|ref|NP_997951.1| ribosomal protein S6 kinase polypep... 845 0.0
gi|2117824|pir||I51901 ribosomal protein S6 kinase 2 (EC 2.7.1.-... 845 0.0
gi|20149547|ref|NP_002944.2| ribosomal protein S6 kinase, 90kDa,... 845 0.0
gi|6537166|gb|AAF15553.1| Rsk-2 [Xenopus laevis] 843 0.0
gi|13592065|ref|NP_112369.1| S6 protein kinase (Rsk-1) [Rattus n... 843 0.0
gi|33354095|dbj|BAC81131.1| RPS6KA3 [Homo sapiens] >gnl|BL_ORD_I... 837 0.0
gi|33304069|gb|AAQ02542.1| ribosomal protein S6 kinase, 90kDa, p... 837 0.0
gi|4759050|ref|NP_004577.1| ribosomal protein S6 kinase, 90kDa, ... 837 0.0
gi|22507357|ref|NP_683747.1| ribosomal protein S6 kinase polypep... 837 0.0
gi|6755374|ref|NP_035429.1| ribosomal protein S6 kinase, polypep... 829 0.0
gi|33243964|gb|AAH55331.1| Ribosomal protein S6 kinase, polypept... 827 0.0
gi|12860267|dbj|BAB31901.1| unnamed protein product [Mus musculus] 827 0.0
gi|49256532|gb|AAH71102.1| Unknown (protein for MGC:81220) [Xeno... 825 0.0
gi|13676454|dbj|BAB41150.1| hypothetical protein [Macaca fascicu... 825 0.0
gi|25005142|gb|AAN71007.1| ribosomal protein S6 kinase [Mus musc... 822 0.0
gi|6166243|sp|Q15349|K6A2_HUMAN Ribosomal protein S6 kinase alph... 821 0.0
gi|6677811|ref|NP_033123.1| ribosomal protein S6 kinase polypept... 820 0.0
gi|19923570|ref|NP_066958.2| ribosomal protein S6 kinase, 90kDa,... 820 0.0
gi|13605770|gb|AAK32877.1| 90-kDa ribosomal protein S6 kinase [R... 819 0.0
gi|33303975|gb|AAQ02495.1| ribosomal protein S6 kinase, 90kDa, p... 818 0.0
gi|125693|sp|P10665|K6AA_XENLA Ribosomal protein S6 kinase II al... 814 0.0
gi|47226221|emb|CAG08368.1| unnamed protein product [Tetraodon n... 812 0.0
gi|50745818|ref|XP_420257.1| PREDICTED: similar to Ribosomal pro... 810 0.0
gi|47230027|emb|CAG10441.1| unnamed protein product [Tetraodon n... 809 0.0
gi|41056055|ref|NP_956367.1| Unknown (protein for MGC:66139); wu... 809 0.0
gi|19310195|dbj|BAB85907.1| p90 ribosomal S6 kinase [Asterina pe... 808 0.0
gi|7657526|ref|NP_055311.1| ribosomal protein S6 kinase, 90kDa, ... 791 0.0
gi|33303997|gb|AAQ02506.1| ribosomal protein S6 kinase, 90kDa, p... 791 0.0
gi|49168616|emb|CAG38803.1| RPS6KA6 [Homo sapiens] 785 0.0
gi|31205767|ref|XP_311835.1| ENSANGP00000018211 [Anopheles gambi... 785 0.0
gi|29789163|ref|NP_080225.1| ribosomal protein S6 kinase polypep... 777 0.0
gi|91277|pir||C32571 ribosomal protein S6 kinase II (EC 2.7.-.-)... 760 0.0
gi|34853790|ref|XP_341759.1| ribosomal protein S6 kinase, 90kD, ... 756 0.0
gi|11181910|emb|CAC16111.1| bA54F22.1.1 (ribosomal protein S6 ki... 743 0.0
gi|32450549|gb|AAH54113.1| Rps6ka6 protein [Mus musculus] 742 0.0
gi|125694|sp|P10666|K6AB_XENLA Ribosomal protein S6 kinase II be... 742 0.0
gi|24643817|ref|NP_523437.2| CG17596-PA [Drosophila melanogaster... 722 0.0
gi|455163|gb|AAA50509.1| p90 ribosomal S6 kinase 722 0.0
gi|28416327|gb|AAO42636.1| SD05277p [Drosophila melanogaster] 710 0.0
gi|47218726|emb|CAG05698.1| unnamed protein product [Tetraodon n... 702 0.0
gi|401774|gb|AAC82495.1| ribosomal protein S6 kinase 3 [Homo sap... 672 0.0
gi|34881194|ref|XP_228473.2| similar to Ribosomal protein S6 kin... 654 0.0
gi|401772|gb|AAC82496.1| ribosomal protein S6 kinase 2 [Homo sap... 618 e-175
gi|50741701|ref|XP_419611.1| PREDICTED: similar to ribosomal pro... 598 e-169
gi|28300431|gb|AAO37581.1| RPS6KA2 [Mus musculus] 566 e-160
gi|33638111|gb|AAQ24165.1| ribosomal protein S6 kinase splice va... 488 e-136
gi|32528295|ref|NP_004746.2| ribosomal protein S6 kinase, 90kDa,... 488 e-136
gi|50748598|ref|XP_421318.1| PREDICTED: similar to ribosomal pro... 488 e-136
gi|26328137|dbj|BAC27809.1| unnamed protein product [Mus musculus] 484 e-135
gi|15277982|gb|AAH12964.1| Ribosomal protein S6 kinase, polypept... 483 e-134
gi|9910454|ref|NP_064308.1| ribosomal protein S6 kinase, polypep... 482 e-134
gi|47221231|emb|CAG13167.1| unnamed protein product [Tetraodon n... 481 e-134
gi|4506735|ref|NP_003933.1| ribosomal protein S6 kinase, 90kDa, ... 481 e-134
gi|3818592|gb|AAC69577.1| ribosome S6 protein kinase [Homo sapiens] 479 e-133
gi|47221835|emb|CAG08889.1| unnamed protein product [Tetraodon n... 476 e-132
gi|34861515|ref|XP_342005.1| similar to ribosomal protein S6 kin... 471 e-131
gi|3411161|gb|AAC67395.1| mitogen- and stress-activated protein ... 465 e-129
gi|48101319|ref|XP_395099.1| similar to ribosomal protein S6 kin... 446 e-123
gi|34935429|ref|XP_234468.2| similar to ribosomal protein S6 kin... 442 e-122
gi|32563675|ref|NP_492204.2| protein kinase and Protein kinase C... 417 e-115
gi|48099894|ref|XP_394955.1| similar to ribosomal protein S6 kin... 412 e-113
gi|39582051|emb|CAE63694.1| Hypothetical protein CBG08209 [Caeno... 412 e-113
gi|7497946|pir||T20232 hypothetical protein C54G4.1 - Caenorhabd... 411 e-113
gi|32528297|ref|NP_872198.1| ribosomal protein S6 kinase, 90kDa,... 367 e-100
gi|31216024|ref|XP_316151.1| ENSANGP00000020399 [Anopheles gambi... 363 9e-99
gi|45430051|ref|NP_991385.1| p70S6K [Bos taurus] >gnl|BL_ORD_ID|... 358 3e-97
gi|12060812|gb|AAG48248.1| p70 ribosomal protein S6 kinase [Arte... 358 4e-97
gi|31418467|gb|AAH53365.1| Unknown (protein for MGC:61512) [Homo... 357 9e-97
gi|26328523|dbj|BAC28000.1| unnamed protein product [Mus musculus] 357 9e-97
gi|109371|pir||S12906 probable ribosomal protein S6 kinase (EC 2... 357 9e-97
gi|23512346|gb|AAH38491.1| Rps6kb1 protein [Mus musculus] 357 9e-97
gi|4506737|ref|NP_003152.1| ribosomal protein S6 kinase, 70kDa, ... 357 9e-97
gi|125695|sp|P23443|K6B1_HUMAN Ribosomal protein S6 kinase (S6K)... 357 9e-97
gi|125696|sp|P21425|K6B1_RAT Ribosomal protein S6 kinase I (S6K)... 357 9e-97
gi|33304209|gb|AAQ02612.1| ribosomal protein S6 kinase, 70kDa, p... 357 9e-97
gi|50758354|ref|XP_415882.1| PREDICTED: similar to Ribosomal pro... 356 1e-96
gi|14010889|ref|NP_114191.1| S6 kinase [Rattus norvegicus] >gnl|... 353 1e-95
gi|47085805|ref|NP_998241.1| zgc:55713 [Danio rerio] >gnl|BL_ORD... 352 2e-95
gi|4582255|emb|CAB40193.1| kinase [Xenopus laevis] 350 6e-95
gi|49118486|gb|AAH73469.1| Rps6kb1-A protein [Xenopus laevis] 350 6e-95
gi|48104993|ref|XP_395876.1| similar to p70 ribosomal protein S6... 350 8e-95
gi|39794417|gb|AAH64239.1| LOC394938 protein [Xenopus tropicalis] 350 1e-94
gi|50415396|gb|AAH78067.1| Unknown (protein for MGC:82916) [Xeno... 348 3e-94
gi|32425471|gb|AAH06106.2| RPS6KB2 protein [Homo sapiens] 343 1e-92
gi|17555946|ref|NP_499447.1| s6 kinase (3M341) [Caenorhabditis e... 342 2e-92
gi|34861393|ref|XP_341980.1| similar to S6 kinase 2 [Rattus norv... 342 2e-92
gi|12643872|sp|Q9UBS0|K6B2_HUMAN Ribosomal protein S6 kinase bet... 342 2e-92
gi|37588972|gb|AAH00094.2| RPS6KB2 protein [Homo sapiens] 342 2e-92
gi|4506739|ref|NP_003943.1| ribosomal protein S6 kinase, 70kDa, ... 342 2e-92
gi|33303901|gb|AAQ02464.1| ribosomal protein S6 kinase, 70kDa, p... 342 2e-92
gi|24658719|ref|NP_523941.2| CG10539-PA [Drosophila melanogaster... 341 4e-92
gi|1778160|gb|AAC47429.1| 70 kDa S6 kinase [Drosophila melanogas... 341 4e-92
gi|10946894|ref|NP_067460.1| ribosomal protein S6 kinase, polype... 340 1e-91
gi|39584758|emb|CAE67653.1| Hypothetical protein CBG13216 [Caeno... 338 2e-91
gi|7434394|pir||JE0377 p70 S6 kinase (EC 2.7.-.-) - human >gnl|B... 338 4e-91
gi|12620233|gb|AAG60621.1| S6 kinase [Aplysia californica] 335 3e-90
gi|23956386|ref|NP_705815.1| ribosomal protein S6 kinase, polype... 333 1e-89
gi|21356509|ref|NP_648432.1| CG6297-PB [Drosophila melanogaster]... 332 2e-89
gi|47210537|emb|CAF90656.1| unnamed protein product [Tetraodon n... 320 7e-86
gi|31242057|ref|XP_321459.1| ENSANGP00000008560 [Anopheles gambi... 306 1e-81
gi|28839796|gb|AAH47896.1| RPS6KA4 protein [Homo sapiens] 300 1e-79
gi|47216837|emb|CAG02728.1| unnamed protein product [Tetraodon n... 298 5e-79
gi|37575481|gb|AAQ93804.1| ribosomal protein S6 kinase [Zea mays] 286 1e-75
gi|7649389|emb|CAB89082.1| S6 ribosomal protein kinase [Asparagu... 285 3e-75
gi|15231959|ref|NP_187484.1| serine/threonine protein kinase (PK... 284 6e-75
gi|464395|sp|P28178|PK2_DICDI Protein kinase 2 >gnl|BL_ORD_ID|12... 283 1e-74
gi|23478593|gb|EAA15636.1| kinase Akt/PKB-related [Plasmodium yo... 283 2e-74
gi|23509142|ref|NP_701810.1| rac-beta serine/threonine protein k... 281 4e-74
gi|2129541|pir||S68463 protein kinase ATPK19 (EC 2.7.1.-) - Arab... 281 4e-74
gi|46909485|gb|AAT06260.1| protein kinase B-like protein [Plasmo... 281 4e-74
gi|1730069|sp|P54644|KRAC_DICDI RAC-family serine/threonine-prot... 278 3e-73
gi|50514024|pdb|1VZO|A Chain A, The Structure Of The N-Terminal ... 278 5e-73
gi|15231960|ref|NP_187485.1| serine/threonine protein kinase (PK... 276 2e-72
gi|21537155|gb|AAM61496.1| putative ribosomal-protein S6 kinase ... 274 7e-72
gi|49067618|ref|XP_398099.1| hypothetical protein UM00484.1 [Ust... 273 2e-71
gi|2760821|gb|AAB95270.1| serine/threonine protein kinase [Entam... 272 3e-71
gi|1362152|pir||S56639 ribosomal protein S6 kinase homolog (clon... 270 1e-70
gi|398924|emb|CAA81204.1| Dakt1 serine-threonine protein kinase ... 269 2e-70
gi|24647358|ref|NP_732114.1| CG4006-PA [Drosophila melanogaster]... 269 2e-70
gi|1079127|pir||A55888 protein kinase (EC 2.7.1.37) akt [similar... 269 2e-70
gi|45551909|ref|NP_732113.2| CG4006-PC [Drosophila melanogaster]... 269 2e-70
gi|17569233|ref|NP_508095.1| protein kinase and Protein kinase C... 268 3e-70
gi|7506247|pir||T16679 hypothetical protein R04A9.5 - Caenorhabd... 268 3e-70
gi|31198165|ref|XP_308030.1| ENSANGP00000019348 [Anopheles gambi... 267 7e-70
gi|8392888|ref|NP_058789.1| murine thymoma viral (v-akt) oncogen... 267 9e-70
gi|21166148|gb|AAM43765.1| similar to Dictyostelium discoideum (... 266 1e-69
gi|50740731|ref|XP_419544.1| PREDICTED: similar to RAC-gamma ser... 266 1e-69
gi|32420379|ref|XP_330633.1| hypothetical protein [Neurospora cr... 266 1e-69
gi|4885549|ref|NP_005456.1| v-akt murine thymoma viral oncogene ... 266 2e-69
gi|11131397|sp|Q9WUA6|AKT3_MOUSE RAC-gamma serine/threonine-prot... 266 2e-69
gi|45433564|ref|NP_035915.2| thymoma viral proto-oncogene 3; PKB... 266 2e-69
gi|33304021|gb|AAQ02518.1| v-akt murine thymoma viral oncogene-l... 266 2e-69
gi|7512664|pir||T17287 protein kinase (EC 2.7.1.37) akt3 short s... 266 2e-69
gi|32307163|ref|NP_859029.1| v-akt murine thymoma viral oncogene... 266 2e-69
gi|47939913|gb|AAH72041.1| MGC78893 protein [Xenopus laevis] 265 3e-69
gi|46107172|ref|XP_380645.1| hypothetical protein FG00469.1 [Gib... 265 3e-69
gi|4502023|ref|NP_001617.1| v-akt murine thymoma viral oncogene ... 265 3e-69
gi|50550707|ref|XP_502826.1| hypothetical protein [Yarrowia lipo... 265 3e-69
gi|13928778|ref|NP_113763.1| thymoma viral proto-oncogene 3; v-a... 265 3e-69
gi|337491|gb|AAA36585.1| rac protein kinase-beta [Homo sapiens] 265 3e-69
gi|50255581|gb|EAL18314.1| hypothetical protein CNBJ2370 [Crypto... 265 5e-69
gi|4249544|dbj|BAA74948.1| p90 S6 kinase [Rattus norvegicus] 264 6e-69
gi|37700244|ref|NP_937789.1| v-akt murine thymoma viral oncogene... 264 8e-69
gi|12539654|gb|AAG59601.1| Akt [Xenopus laevis] 263 1e-68
gi|6680674|ref|NP_031460.1| thymoma viral proto-oncogene 2; RAC-... 263 1e-68
gi|47230282|emb|CAG10696.1| unnamed protein product [Tetraodon n... 263 1e-68
gi|28279352|gb|AAH46261.1| Akt2-prov protein [Xenopus laevis] 263 1e-68
gi|47213969|emb|CAG00660.1| unnamed protein product [Tetraodon n... 263 1e-68
gi|26324816|dbj|BAC26162.1| unnamed protein product [Mus musculus] 263 1e-68
gi|46107178|ref|XP_380648.1| hypothetical protein FG00472.1 [Gib... 263 1e-68
gi|32420385|ref|XP_330636.1| hypothetical protein [Neurospora cr... 263 2e-68
gi|47223805|emb|CAF98575.1| unnamed protein product [Tetraodon n... 263 2e-68
gi|16266771|dbj|BAB69974.1| kinase Akt/PKB [Asterina pectinifera] 263 2e-68
gi|17980212|gb|AAL50556.1| serine-threonine protein kinase PK2 [... 262 2e-68
gi|45384254|ref|NP_990386.1| serine/threonine protein kinase [Ga... 262 2e-68
gi|45187484|ref|NP_983707.1| ADL389Wp [Eremothecium gossypii] >g... 262 3e-68
gi|19075510|ref|NP_588010.1| putative proliferation-associated s... 262 3e-68
gi|30725240|gb|AAP37655.1| serine/threonine protein kinase Akt [... 261 4e-68
gi|47086403|ref|NP_997980.1| v-akt murine thymoma viral oncogene... 261 5e-68
gi|50287865|ref|XP_446362.1| unnamed protein product [Candida gl... 260 9e-68
gi|50420447|ref|XP_458760.1| unnamed protein product [Debaryomyc... 259 1e-67
gi|48138240|ref|XP_396874.1| similar to serine/threonine protein... 259 1e-67
gi|9844082|emb|CAC03748.1| cAMP-dependent protein kinase catalyt... 259 2e-67
gi|38110989|gb|EAA56628.1| hypothetical protein MG06599.4 [Magna... 259 2e-67
gi|732542|gb|AAA64341.1| cAMP-dependent protein kinase 258 3e-67
gi|46122935|ref|XP_386021.1| hypothetical protein FG05845.1 [Gib... 258 3e-67
gi|37926827|pdb|1MRV|A Chain A, Crystal Structure Of An Inactive... 258 4e-67
gi|31615318|pdb|1GZN|A Chain A, Structure Of Pkb Kinase Domain 258 4e-67
gi|19115752|ref|NP_594840.1| serine/threonine protein kinase [Sc... 258 4e-67
gi|31615317|pdb|1GZK|A Chain A, Molecular Mechanism For The Regu... 258 4e-67
gi|227604|prf||1707301A protein kinase 258 6e-67
gi|27066378|pdb|1O6K|A Chain A, Structure Of Activated Form Of P... 258 6e-67
gi|6321999|ref|NP_012075.1| protein kinase involved in growth co... 258 6e-67
gi|4426|emb|CAA31073.1| unnamed protein product [Saccharomyces c... 258 6e-67
gi|27066381|pdb|1O6L|A Chain A, Crystal Structure Of An Activate... 258 6e-67
gi|730723|sp|P11792|SCH9_YEAST Serine/threonine-protein kinase S... 258 6e-67
gi|50552438|ref|XP_503629.1| hypothetical protein [Yarrowia lipo... 257 7e-67
gi|400144|sp|P31750|KRAC_MOUSE RAC-alpha serine/threonine-protei... 257 7e-67
gi|50303505|ref|XP_451694.1| unnamed protein product [Kluyveromy... 256 1e-66
gi|33303885|gb|AAQ02456.1| v-akt murine thymoma viral oncogene h... 256 1e-66
gi|400112|sp|P31748|KAKT_MLVAT AKT kinase transforming protein 256 1e-66
gi|15100164|ref|NP_150233.1| v-akt murine thymoma viral oncogene... 256 1e-66
gi|12653417|gb|AAH00479.1| AKT1 protein [Homo sapiens] 256 1e-66
gi|4885061|ref|NP_005154.1| serine/threonine protein kinase; Mur... 256 1e-66
gi|6753034|ref|NP_033782.1| thymoma viral proto-oncogene 1 [Mus ... 256 1e-66
gi|538540|pir||A40831 gag-akt polyprotein - AKT8 murine leukemia... 256 1e-66
gi|3688803|gb|AAC62398.1| unknown [Xenopus laevis] 256 2e-66
gi|33146662|dbj|BAC80008.1| putative S6 ribosomal protein kinase... 256 2e-66
gi|25168263|ref|NP_005618.2| serum/glucocorticoid regulated kina... 256 2e-66
gi|3914977|sp|O00141|SGK1_HUMAN Serine/threonine-protein kinase ... 256 2e-66
gi|33303865|gb|AAQ02446.1| serum/glucocorticoid regulated kinase... 256 2e-66
gi|49116933|gb|AAH73077.1| Sgk protein [Xenopus laevis] 255 3e-66
gi|13431833|sp|Q9XT18|SGK1_RABIT Serine/threonine-protein kinase... 255 3e-66
gi|477098|pir||A48094 serum and glucocorticoid-regulated kinase ... 255 3e-66
gi|45383215|ref|NP_989807.1| serum- and glucocorticoid-induced k... 255 3e-66
gi|6755490|ref|NP_035491.1| serum/glucocorticoid regulated kinas... 255 4e-66
gi|47124333|gb|AAH70401.1| Sgk protein [Mus musculus] 255 4e-66
gi|46442847|gb|EAL02133.1| hypothetical protein CaO19.829 [Candi... 254 5e-66
gi|38109796|gb|EAA55609.1| hypothetical protein MG01260.4 [Magna... 254 5e-66
gi|38109783|gb|EAA55600.1| hypothetical protein MG01251.4 [Magna... 254 5e-66
gi|47220463|emb|CAG03243.1| unnamed protein product [Tetraodon n... 254 6e-66
gi|9507093|ref|NP_062105.1| serum/glucocorticoid regulated kinas... 253 1e-65
gi|49257650|gb|AAH74305.1| Unknown (protein for MGC:84110) [Xeno... 253 1e-65
gi|26333955|dbj|BAC30695.1| unnamed protein product [Mus musculus] 253 1e-65
gi|32414173|ref|XP_327566.1| hypothetical protein ( (AY029769) p... 253 1e-65
gi|458284|gb|AAA57318.1| serine/threonine protein kinase 253 1e-65
gi|15072452|gb|AAK40343.1| protein kinase 1 [Cryphonectria paras... 253 1e-65
gi|19075330|ref|NP_587830.1| putative protein kinase [Schizosacc... 253 2e-65
gi|49097300|ref|XP_410110.1| hypothetical protein AN5973.2 [Aspe... 253 2e-65
gi|12848541|dbj|BAB27991.1| unnamed protein product [Mus musculus] 251 4e-65
gi|33303995|gb|AAQ02505.1| serum/glucocorticoid regulated kinase... 250 9e-65
gi|20127541|ref|NP_057360.2| serum/glucocorticoid regulated kina... 250 9e-65
gi|3116066|emb|CAA11528.1| s-sgk2 [Squalus acanthias] 250 9e-65
gi|33878427|gb|AAH14037.2| SGK2 protein [Homo sapiens] 250 9e-65
gi|25168261|ref|NP_733794.1| serum/glucocorticoid regulated kina... 250 9e-65
gi|25145932|ref|NP_741614.1| AKT kinase (62.7 kD) (akt-1) [Caeno... 249 2e-64
gi|50292225|ref|XP_448545.1| unnamed protein product [Candida gl... 249 2e-64
gi|40363533|ref|NP_954682.1| serum/glucocorticoid regulated kina... 249 2e-64
gi|35481|emb|CAA43372.1| human protein kinase B [Homo sapiens] 249 3e-64
gi|49093828|ref|XP_408375.1| hypothetical protein AN4238.2 [Aspe... 248 3e-64
gi|27806747|ref|NP_776411.1| v-akt murine thymoma viral oncogene... 248 3e-64
gi|1362234|pir||S55694 protein kinase (EC 2.7.1.37) sck1, cAMP-d... 248 4e-64
gi|19114666|ref|NP_593754.1| cAMP-dependent protein kinase, sck1... 248 4e-64
gi|46433231|gb|EAK92679.1| hypothetical protein CaO19.399 [Candi... 248 4e-64
gi|49067855|ref|XP_398217.1| hypothetical protein UM00602.1 [Ust... 248 4e-64
gi|45185202|ref|NP_982919.1| ABL028Wp [Eremothecium gossypii] >g... 247 7e-64
gi|7305483|ref|NP_038759.1| serum/glucocorticoid regulated kinas... 247 7e-64
gi|34860642|ref|XP_342571.1| serum/glucocorticoid regulated kina... 247 1e-63
gi|50254457|gb|EAL17206.1| hypothetical protein CNBN0340 [Crypto... 246 1e-63
gi|17402861|gb|AAF27051.2| SGK-like protein SGKL [Homo sapiens] 246 1e-63
gi|18959280|ref|NP_573483.1| serum/glucocorticoid regulated kina... 246 2e-63
gi|17390848|gb|AAH18363.1| Sgk3 protein [Mus musculus] 246 2e-63
gi|39593304|emb|CAE64774.1| Hypothetical protein CBG09565 [Caeno... 246 2e-63
gi|17557832|ref|NP_505637.1| AKT kinase (62.2 kD) (akt-1) [Caeno... 246 2e-63
gi|3116064|emb|CAA11527.1| s-sgk1 [Squalus acanthias] 246 2e-63
gi|33303813|gb|AAQ02420.1| serum/glucocorticoid regulated kinase... 245 3e-63
gi|31563382|ref|NP_037389.4| serum/glucocorticoid regulated kina... 245 3e-63
gi|6466010|gb|AAF12758.1| protein kinase [Homo sapiens] >gnl|BL_... 245 3e-63
gi|445069|prf||1908384A protein kinase 245 3e-63
gi|6322723|ref|NP_012796.1| 76.5 kDa Serine/threonine protein ki... 245 3e-63
gi|172181|gb|AAA34880.1| protein kinase 245 3e-63
gi|20072336|gb|AAH26549.1| Serum/glucocorticoid regulated kinase... 245 4e-63
gi|13591549|emb|CAC36348.1| dJ590P13.1 (ribosomal protein S6 kin... 245 4e-63
gi|26327211|dbj|BAC27349.1| unnamed protein product [Mus musculus] 245 4e-63
gi|3114989|emb|CAA73554.1| Serine/Threonine protein kinase [Syco... 244 5e-63
gi|25146870|ref|NP_741871.1| protein kinase C (77.6 kD) (pkc-2) ... 244 8e-63
gi|1778590|gb|AAB40868.1| protein kinase C2 A isoform [Caenorhab... 244 8e-63
gi|13592027|ref|NP_112347.1| protein kinase C-eta [Rattus norveg... 243 1e-62
gi|50731568|ref|XP_418280.1| PREDICTED: similar to Serine/threon... 243 1e-62
gi|7500109|pir||T21523 protein kinase (EC 2.7.1.37) akt-2 long s... 243 1e-62
gi|125563|sp|P23298|KPCL_MOUSE Protein kinase C, eta type (nPKC-... 243 2e-62
gi|228058|prf||1716374A protein kinase C I 242 2e-62
gi|49359177|gb|AAT65503.1| protein kinase C epsilon [Rattus norv... 242 2e-62
gi|31543511|ref|NP_032882.2| protein kinase C, eta [Mus musculus... 242 3e-62
gi|49095312|ref|XP_409117.1| hypothetical protein AN4980.2 [Aspe... 242 3e-62
gi|47230126|emb|CAG10540.1| unnamed protein product [Tetraodon n... 242 3e-62
gi|48097317|ref|XP_391874.1| similar to ENSANGP00000009078 [Apis... 241 4e-62
gi|50291879|ref|XP_448372.1| unnamed protein product [Candida gl... 241 5e-62
gi|6225593|sp|Q16974|KPC1_APLCA Calcium-dependent protein kinase... 241 5e-62
gi|4885563|ref|NP_005391.1| protein kinase C, epsilon [Homo sapi... 241 5e-62
gi|50427081|ref|XP_462147.1| unnamed protein product [Debaryomyc... 241 5e-62
gi|31206439|ref|XP_312175.1| ENSANGP00000022036 [Anopheles gambi... 241 5e-62
gi|39592150|emb|CAE75370.1| Hypothetical protein CBG23354 [Caeno... 241 7e-62
gi|28557781|ref|NP_006246.2| protein kinase C, eta [Homo sapiens... 241 7e-62
gi|50755717|ref|XP_414868.1| PREDICTED: similar to Protein kinas... 241 7e-62
gi|50547917|ref|XP_501428.1| hypothetical protein [Yarrowia lipo... 241 7e-62
gi|47225434|emb|CAG11917.1| unnamed protein product [Tetraodon n... 240 9e-62
gi|1346393|sp|P24723|KPCL_HUMAN Protein kinase C, eta type (nPKC... 240 9e-62
gi|104176|pir||S20964 ribosomal protein S6 kinase (EC 2.7.1.-), ... 240 9e-62
gi|6755084|ref|NP_035234.1| protein kinase C, epsilon [Mus muscu... 240 1e-61
gi|3114956|emb|CAA73553.1| Serine/Threonine protein kinase [Sube... 240 1e-61
gi|2073446|emb|CAA73362.1| protein kinase C [Hydra vulgaris] 240 1e-61
gi|2073444|emb|CAA73363.1| protein kinase C [Hydra vulgaris] 240 1e-61
gi|66734|pir||KIRBCE protein kinase C (EC 2.7.1.-) epsilon - rabbit 239 2e-61
gi|125556|sp|P10830|KPCE_RABIT Protein kinase C, epsilon type (n... 239 2e-61
gi|16648134|gb|AAL25332.1| GH13631p [Drosophila melanogaster] 239 2e-61
gi|39930373|ref|NP_058867.1| protein kinase C, epsilon [Rattus n... 239 2e-61
gi|7504545|pir||T22856 hypothetical protein F57F5.5 - Caenorhabd... 239 2e-61
gi|17562588|ref|NP_506014.1| protein kinase C (80.2 kD) (pkc-1) ... 239 2e-61
gi|50304295|ref|XP_452097.1| unnamed protein product [Kluyveromy... 239 3e-61
gi|4157977|emb|CAA76911.1| protein kinase C [Geodia cydonium] 239 3e-61
gi|50748818|ref|XP_421417.1| PREDICTED: similar to protein kinas... 239 3e-61
gi|24650924|ref|NP_524545.2| CG1954-PA [Drosophila melanogaster]... 238 3e-61
gi|44890402|gb|AAH66842.1| Rps6kb2 protein [Mus musculus] 238 3e-61
gi|125547|sp|P13678|KPC3_DROME Protein kinase C (PKC) (dPKC98F) ... 238 3e-61
gi|630707|pir||A53530 protein kinase C (EC 2.7.1.-) epsilon-rela... 238 3e-61
gi|6016442|sp|Q25378|KPC1_LYTPI Protein kinase C >gnl|BL_ORD_ID|... 238 5e-61
gi|35396778|gb|AAQ84895.1| protein kinase C 1 [Cryptococcus neof... 238 6e-61
gi|50259580|gb|EAL22253.1| hypothetical protein CNBC3910 [Crypto... 238 6e-61
gi|20385903|gb|AAM21494.1| protein kinase Sch9 [Cryptococcus neo... 237 8e-61
gi|47213332|emb|CAF93963.1| unnamed protein product [Tetraodon n... 237 8e-61
gi|25146791|ref|NP_510357.2| AKT kinase (55.8 kD) (akt-2) [Caeno... 237 8e-61
gi|41053359|ref|NP_957323.1| similar to Protein C kinase 53E [Da... 237 1e-60
gi|39585528|emb|CAE65288.1| Hypothetical protein CBG10201 [Caeno... 237 1e-60
gi|6981398|ref|NP_036845.1| protein kinase C, beta; protein kina... 237 1e-60
gi|125540|sp|P04410|KPCB_MOUSE Protein kinase C, beta type (PKC-... 237 1e-60
gi|2822146|gb|AAB97933.1| Protein kinase C beta (5' partial) spl... 236 2e-60
gi|47157322|ref|NP_997700.1| protein kinase C, beta isoform 1; p... 236 2e-60
gi|125539|sp|P05772|KPCB_RABIT Protein kinase C, beta type (PKC-... 236 2e-60
gi|66721|pir||KIRTC1 protein kinase C (EC 2.7.1.-) beta-I - rat ... 236 2e-60
gi|631936|pir||S41099 protein kinase (EC 2.7.1.37), cAMP-depende... 235 3e-60
gi|32566197|ref|NP_741872.2| protein kinase C (78.0 kD) (pkc-2) ... 235 3e-60
gi|1778592|gb|AAB40869.1| protein kinase C2 B isoform [Caenorhab... 235 3e-60
gi|507141|gb|AAA19440.1| cAMP-dependent protein kinase catalytic... 235 3e-60
gi|7511603|pir||T15903 protein kinase C homolog - Caenorhabditis... 235 3e-60
gi|50555624|ref|XP_505220.1| hypothetical protein [Yarrowia lipo... 235 3e-60
gi|545623|gb|AAB30032.1| cAMP-dependent protein kinase C subunit... 235 3e-60
gi|21392563|gb|AAA68709.2| Protein kinase c protein 2, isoform c... 235 3e-60
gi|39596192|emb|CAE69829.1| Hypothetical protein CBG16150 [Caeno... 235 4e-60
gi|125552|sp|P05696|KPCA_RAT Protein kinase C, alpha type (PKC-a... 235 4e-60
gi|66717|pir||KIMSCA protein kinase C (EC 2.7.1.-) alpha - mouse... 235 4e-60
gi|125551|sp|P10102|KPCA_RABIT Protein kinase C, alpha type (PKC... 235 4e-60
gi|4506067|ref|NP_002728.1| protein kinase C, alpha; protein kin... 235 4e-60
gi|47224245|emb|CAG09091.1| unnamed protein product [Tetraodon n... 235 4e-60
gi|303941|dbj|BAA03268.1| protein kinase [Schizosaccharomyces po... 235 4e-60
gi|19112742|ref|NP_595950.1| protein kinase c-like 2 [Schizosacc... 235 4e-60
gi|50740446|ref|XP_419464.1| PREDICTED: similar to Protein kinas... 235 4e-60
gi|34874121|ref|XP_343976.1| protein kinase C, alpha [Rattus nor... 235 4e-60
gi|27806089|ref|NP_776860.1| protein kinase, C alpha [Bos taurus... 234 5e-60
gi|41055807|ref|NP_957272.1| similar to protein kinase C, beta [... 234 5e-60
gi|24654282|ref|NP_725626.1| CG6622-PB [Drosophila melanogaster]... 234 7e-60
gi|35396780|gb|AAQ84896.1| protein kinase C 1 [Cryptococcus neof... 234 7e-60
gi|17136402|ref|NP_476682.1| CG6622-PA [Drosophila melanogaster]... 234 7e-60
gi|6016444|sp|Q16975|KPC2_APLCA Calcium-independent protein kina... 234 9e-60
gi|50303809|ref|XP_451851.1| unnamed protein product [Kluyveromy... 234 9e-60
gi|104168|pir||B37237 protein kinase C (EC 2.7.1.-) II - African... 233 1e-59
gi|6323751|ref|NP_013822.1| protein kinase; Ypk2p [Saccharomyces... 233 1e-59
gi|227491|prf||1704381B protein kinase C II 233 1e-59
gi|37702159|gb|AAR00731.1| protein kinase C type beta [Schistoso... 233 1e-59
gi|55132|emb|CAA36907.1| protein kinase C [Mus musculus] >gnl|BL... 233 2e-59
gi|125550|sp|P20444|KPCA_MOUSE Protein kinase C, alpha type (PKC... 232 3e-59
gi|6755078|ref|NP_035231.1| protein kinase C, alpha [Mus musculu... 232 3e-59
gi|445070|prf||1908384B protein kinase 232 3e-59
gi|1085218|pir||S53726 protein kinase PKN - African clawed frog ... 232 3e-59
gi|206189|gb|AAA41875.1| protein kinase C type II 231 4e-59
gi|6679345|ref|NP_032881.1| protein kinase C, beta [Mus musculus... 231 4e-59
gi|22023043|emb|CAD30698.1| protein kinase C, alpha type [Takifu... 231 4e-59
gi|3114991|emb|CAA73557.1| Serine/Threonine protein kinase [Syco... 231 6e-59
gi|2144416|pir||OKBYC1 protein kinase (EC 2.7.1.37), cAMP-depend... 231 6e-59
gi|27807061|ref|NP_777012.1| protein kinase C, beta 1 polypeptid... 231 7e-59
gi|66724|pir||KIRTC2 protein kinase C (EC 2.7.1.-) beta-II - rat... 231 7e-59
gi|66725|pir||KIRBC2 protein kinase C (EC 2.7.1.-) beta-II - rab... 231 7e-59
gi|20127450|ref|NP_002729.2| protein kinase C, beta isoform 2; p... 231 7e-59
gi|462434|sp|P34099|KAPC_DICDI cAMP-dependent protein kinase cat... 231 7e-59
gi|32411229|ref|XP_326095.1| hypothetical protein ( (AF264760) c... 231 7e-59
gi|48096660|ref|XP_394743.1| similar to CG10524-PA [Apis mellifera] 231 7e-59
gi|2822147|gb|AAB97934.1| Protein kinase C beta (5' partial) spl... 231 7e-59
gi|17570293|ref|NP_510647.1| serum and Glucocorticoid inducible ... 230 9e-59
gi|22085162|gb|AAM90321.1| putative protein kinase C epsilon [Li... 230 9e-59
gi|28558156|sp|Q8R4U9|SGK2_RAT Serine/threonine-protein kinase S... 230 9e-59
gi|47224750|emb|CAG00344.1| unnamed protein product [Tetraodon n... 229 2e-58
gi|49119294|gb|AAH73353.1| Unknown (protein for MGC:80770) [Xeno... 229 2e-58
gi|125208|sp|P06244|KAPA_YEAST cAMP-dependent protein kinase typ... 229 2e-58
gi|104167|pir||A37237 protein kinase C (EC 2.7.1.-) I - African ... 229 3e-58
gi|38197376|gb|AAH61836.1| Protein kinase C-like 1 [Rattus norve... 229 3e-58
gi|34860837|ref|XP_215718.2| similar to protein kinase C-like 2 ... 228 5e-58
gi|39596252|emb|CAE69890.1| Hypothetical protein CBG16239 [Caeno... 228 5e-58
gi|4150896|emb|CAA73682.1| serine /threonine protein kinase [Rha... 228 5e-58
gi|50604098|gb|AAH78065.1| Unknown (protein for MGC:82897) [Xeno... 228 5e-58
gi|50288647|ref|XP_446753.1| unnamed protein product [Candida gl... 228 5e-58
gi|6322682|ref|NP_012755.1| Involved in nutrient control of cell... 228 5e-58
gi|32813439|ref|NP_796236.2| protein kinase N1; serine/threonine... 228 5e-58
gi|6322297|ref|NP_012371.1| putative catalytic subunit of cAMP-d... 228 5e-58
gi|2911462|gb|AAC04357.1| serine/threonine protein kinase [Colle... 228 6e-58
gi|47221653|emb|CAF97918.1| unnamed protein product [Tetraodon n... 228 6e-58
gi|2996092|gb|AAC08427.1| rac serine-threonine kinase homolog [T... 228 6e-58
gi|50751352|ref|XP_422357.1| PREDICTED: similar to protein kinas... 228 6e-58
gi|50548799|ref|XP_501869.1| hypothetical protein [Yarrowia lipo... 228 6e-58
gi|16905491|gb|AAL31374.1| cardiolipin/protease-activated protei... 228 6e-58
gi|14719777|pdb|1FOT|A Chain A, Structure Of The Unliganded Camp... 227 8e-58
gi|50757861|ref|XP_415682.1| PREDICTED: similar to Protein kinas... 227 8e-58
gi|543444|pir||JC2130 protein kinase (EC 2.7.1.37) - rat 227 8e-58
gi|8394047|ref|NP_058871.1| protein kinase C-like 1; protein kin... 227 8e-58
gi|34303892|dbj|BAC82421.1| hypothetical protein [Entamoeba hist... 227 8e-58
gi|39596349|emb|CAE69987.1| Hypothetical protein CBG16386 [Caeno... 227 8e-58
gi|173013|gb|AAA35166.1| cAMP-dependent protein kinase subunit (... 227 1e-57
gi|9716257|emb|CAC01625.1| protein kinase C homologue [Tuber bor... 227 1e-57
gi|9858805|gb|AAG01142.1| protein kinase A [Blumeria graminis] 226 1e-57
gi|1170687|sp|P43057|KPC1_CANAL Protein kinase C-like 1 (PKC 1) ... 226 1e-57
gi|50308473|ref|XP_454238.1| unnamed protein product [Kluyveromy... 226 1e-57
gi|47212674|emb|CAF94155.1| unnamed protein product [Tetraodon n... 226 2e-57
gi|46444978|gb|EAL04249.1| hypothetical protein CaO19.13322 [Can... 226 2e-57
gi|6174910|sp|Q16512|PKL1_HUMAN Protein kinase C-like 1 (Protein... 226 2e-57
gi|47132589|ref|NP_002732.3| protein kinase N1 isoform 2; serine... 226 2e-57
gi|1093486|prf||2104208A protein kinase C-related kinase:ISOTYPE... 226 2e-57
gi|47132591|ref|NP_998725.1| protein kinase N1 isoform 1; serine... 226 2e-57
gi|33303981|gb|AAQ02498.1| protein kinase C-like 2 [synthetic co... 225 3e-57
gi|5453974|ref|NP_006247.1| protein kinase N2; protein kinase C-... 225 3e-57
gi|25304069|gb|AAH40061.1| Protein kinase C-like 1, isoform 2 [H... 225 3e-57
gi|2586064|gb|AAC13357.1| protein kinase C-related kinase 2 [Xen... 225 3e-57
gi|7522131|pir||T28666 protein kinase C-related kinase PRKSD - S... 225 3e-57
gi|11493219|emb|CAC17575.1| dJ905H16.1 (protein kinase C-like 2)... 225 3e-57
gi|18056644|gb|AAL58094.1| protein kinase A catalytic subunit [T... 225 4e-57
gi|629915|pir||S47220 protein kinase C (EC 2.7.1.-) PKC1 - yeast... 225 4e-57
gi|30354738|gb|AAH52073.1| Pkn2 protein [Mus musculus] 224 5e-57
gi|26350541|dbj|BAC38910.1| unnamed protein product [Mus musculus] 224 5e-57
gi|7511605|pir||T33399 protein kinase C homolog tpa-1, splice fo... 223 1e-56
gi|17542634|ref|NP_499861.1| tetradecanoyl Phorbol Acetate resis... 223 1e-56
gi|17542632|ref|NP_499860.1| tetradecanoyl Phorbol Acetate resis... 223 1e-56
gi|28629057|gb|AAO49460.1| protein kinase C [Leptosphaeria macul... 223 1e-56
gi|50294600|ref|XP_449711.1| unnamed protein product [Candida gl... 223 1e-56
gi|303529|dbj|BAA03556.1| TPA-1 [Caenorhabditis elegans] 223 1e-56
gi|30172014|gb|AAP20604.1| protein kinase C [Pichia pastoris] 223 2e-56
gi|49084020|ref|XP_404243.1| KPC1_ASPNG Protein kinase C-like [A... 223 2e-56
gi|1085381|pir||S48705 serine/threonine protein kinase - human >... 223 2e-56
gi|31198671|ref|XP_308283.1| ENSANGP00000010728 [Anopheles gambi... 223 2e-56
gi|31198669|ref|XP_308282.1| ENSANGP00000022695 [Anopheles gambi... 223 2e-56
gi|30520013|ref|NP_848769.1| serine/threonine kinase 7; protein ... 223 2e-56
gi|38524427|dbj|BAD02338.1| protein kinase C [Emericella nidulans] 223 2e-56
gi|6225860|sp|O08874|PKL2_RAT Protein kinase C-like 2 (Protein-k... 223 2e-56
gi|2499576|sp|Q00078|KPC1_ASPNG Protein kinase C-like >gnl|BL_OR... 223 2e-56
gi|45190492|ref|NP_984746.1| AEL115Cp [Eremothecium gossypii] >g... 222 3e-56
gi|18859259|ref|NP_571930.1| protein kinase C, iota [Danio rerio... 222 3e-56
gi|28502762|gb|AAH47164.1| Prkci protein [Danio rerio] 222 3e-56
gi|49899150|gb|AAH75736.1| Prkci protein [Danio rerio] 222 3e-56
gi|103330|pir||A32545 protein kinase C (EC 2.7.1.-) - fruit fly ... 222 3e-56
gi|4938231|emb|CAA28890.2| protein kinase C [Drosophila melanoga... 222 3e-56
gi|6456802|emb|CAB61490.1| cAMP-dependent protein kinase A catal... 222 3e-56
gi|4587211|dbj|BAA76665.1| cAMP-dependent protein kinase catalyt... 222 3e-56
gi|241277|gb|AAB20716.1| serine/threonine protein kinase [Dictyo... 222 3e-56
gi|6016441|sp|O42632|KPC1_COCHE Protein kinase C-like >gnl|BL_OR... 222 3e-56
gi|50548247|ref|XP_501593.1| hypothetical protein [Yarrowia lipo... 222 3e-56
gi|46125747|ref|XP_387427.1| hypothetical protein FG07251.1 [Gib... 222 3e-56
gi|45185877|ref|NP_983593.1| ACR191Cp [Eremothecium gossypii] >g... 221 4e-56
gi|31240263|ref|XP_320545.1| ENSANGP00000008680 [Anopheles gambi... 221 4e-56
gi|50294680|ref|XP_449751.1| unnamed protein product [Candida gl... 221 4e-56
gi|39587559|emb|CAE58497.1| Hypothetical protein CBG01645 [Caeno... 221 6e-56
gi|28573943|ref|NP_788292.1| CG2049-PF [Drosophila melanogaster]... 221 6e-56
gi|28573947|ref|NP_788294.1| CG2049-PE [Drosophila melanogaster]... 221 6e-56
gi|38110717|gb|EAA56397.1| hypothetical protein MG06368.4 [Magna... 221 6e-56
gi|15292295|gb|AAK93416.1| LD45949p [Drosophila melanogaster] 221 6e-56
gi|28573941|ref|NP_788291.1| CG2049-PC [Drosophila melanogaster]... 221 6e-56
gi|28573939|ref|NP_788290.1| CG2049-PB [Drosophila melanogaster]... 221 6e-56
gi|17136716|ref|NP_476863.1| CG6518-PA [Drosophila melanogaster]... 221 7e-56
gi|125558|sp|P05128|KPCG_BOVIN Protein kinase C, gamma type (PKC... 221 7e-56
gi|125560|sp|P10829|KPCG_RABIT Protein kinase C, gamma type (PKC... 221 7e-56
gi|6755080|ref|NP_035232.1| protein kinase C, gamma [Mus musculu... 221 7e-56
gi|35497|emb|CAA78820.1| protein kinase C gamma [Homo sapiens] 221 7e-56
gi|13384594|ref|NP_002730.1| protein kinase C, gamma; Protein ki... 221 7e-56
gi|34856774|ref|XP_342224.1| protein kinase C, lambda [Rattus no... 220 1e-55
gi|34880556|ref|XP_343789.1| similar to ribosomal protein S6 kin... 220 1e-55
gi|631750|pir||A53758 protein kinase C (EC 2.7.1.-) lambda - mouse 220 1e-55
gi|6679349|ref|NP_032883.1| protein kinase C, lambda [Mus muscul... 220 1e-55
gi|516040|gb|AAA93199.1| cAMP-dependent protein kinase catalytic... 220 1e-55
gi|48255885|ref|NP_002731.3| protein kinase C, iota; atypical pr... 220 1e-55
gi|4325024|gb|AAD17221.1| cAMP-dependent protein kinase catalyti... 220 1e-55
gi|33304197|gb|AAQ02606.1| protein kinase C, iota [synthetic con... 220 1e-55
gi|46445417|gb|EAL04686.1| hypothetical protein CaO19.12357 [Can... 220 1e-55
gi|4996216|dbj|BAA78372.1| PKC lambda [Rattus norvegicus] 220 1e-55
gi|38707442|dbj|BAD04044.1| catalytic subunit of cAMP-dependent ... 220 1e-55
gi|45198429|ref|NP_985458.1| AFL090Wp [Eremothecium gossypii] >g... 220 1e-55
gi|50757368|ref|XP_415491.1| PREDICTED: similar to protein kinas... 220 1e-55
gi|30585051|gb|AAP36798.1| Homo sapiens protein kinase C, zeta [... 220 1e-55
gi|6319363|ref|NP_009445.1| Protein Kinase C; Pkc1p [Saccharomyc... 220 1e-55
gi|172177|gb|AAA34878.1| protein kinase C-like protein (PKC1) 220 1e-55
gi|14165515|gb|AAH08058.1| Protein kinase C, zeta [Homo sapiens]... 220 1e-55
gi|10864650|ref|NP_002735.2| protein kinase C, zeta [Homo sapien... 220 1e-55
gi|4558499|gb|AAD22633.1| protein kinase C; serine/threonine pro... 220 1e-55
gi|35501|emb|CAA78813.1| protein kinase C zeta [Homo sapiens] 220 1e-55
gi|83398|pir||S22258 probable protein kinase KIN82 (EC 2.7.1.-) ... 219 2e-55
gi|33589302|gb|AAQ22418.1| RH55776p [Drosophila melanogaster] 219 2e-55
gi|50425563|ref|XP_461377.1| unnamed protein product [Debaryomyc... 219 2e-55
gi|48141855|ref|XP_397273.1| similar to ENSANGP00000008680 [Apis... 219 2e-55
gi|50415747|ref|XP_457493.1| unnamed protein product [Debaryomyc... 219 2e-55
gi|50752484|ref|XP_422798.1| PREDICTED: similar to Protein kinas... 219 2e-55
gi|46436399|gb|EAK95762.1| hypothetical protein CaO19.9817 [Cand... 219 2e-55
gi|11596395|gb|AAG38600.1| cAMP-dependent protein kinase catalyt... 219 2e-55
gi|6016443|sp|P87253|KPC1_NEUCR Protein kinase C-like >gnl|BL_OR... 219 2e-55
gi|24641525|ref|NP_511171.2| CG10524-PA [Drosophila melanogaster... 219 2e-55
gi|12698444|gb|AAK01549.1| cAMP-dependent protein kinase catalyt... 219 2e-55
gi|6102720|emb|CAB59301.1| protein kinase C [Botryotinia fuckeli... 219 2e-55
gi|7578502|gb|AAF64072.1| protein kinase A [Candida albicans] 219 2e-55
gi|18314569|gb|AAH22016.1| Protein kinase C, iota [Homo sapiens] 219 3e-55
gi|50306467|ref|XP_453207.1| unnamed protein product [Kluyveromy... 219 3e-55
gi|478322|pir||JN0877 protein kinase C (EC 2.7.1.-) zeta - human... 219 3e-55
gi|206195|gb|AAA41878.1| protein kinase C zeta subspecies 218 4e-55
gi|32411837|ref|XP_326399.1| PROTEIN KINASE C-LIKE [Neurospora c... 218 4e-55
gi|24418929|ref|NP_722500.1| protein kinase N3; hypothetical pro... 218 4e-55
gi|173011|gb|AAA35165.1| cAMP-dependent protein kinase subunit (... 218 4e-55
gi|2911458|gb|AAC04355.1| cAMP-dependent protein kinase catalyti... 218 4e-55
gi|10383810|ref|NP_010015.2| Putative serine/threonine protein k... 218 4e-55
gi|11968080|ref|NP_071952.1| protein kinase C, zeta; 14 - 3 - 3 ... 218 4e-55
gi|6679355|ref|NP_032886.1| protein kinase C, zeta [Mus musculus... 218 4e-55
gi|3024076|sp|O19111|KPCZ_RABIT Protein kinase C, zeta type (nPK... 218 4e-55
gi|31158356|dbj|BAC76975.1| protein kinase C-zeta 2 [Mus musculus] 218 4e-55
gi|50758633|ref|XP_417346.1| PREDICTED: similar to serum/glucoco... 218 5e-55
gi|6325053|ref|NP_015121.1| Involved in nutrient control of cell... 218 5e-55
gi|4322298|gb|AAD16003.1| cAMP-dependent protein kinase catalyti... 218 5e-55
gi|46136289|ref|XP_389836.1| hypothetical protein FG09660.1 [Gib... 218 6e-55
gi|10334453|emb|CAC10200.1| bA563J2.2 (protein kinase C theta ) ... 218 6e-55
gi|32480481|dbj|BAC79120.1| protein kinase-delta2 [Xenopus laevis] 218 6e-55
>gi|17508705|ref|NP_492320.1| ribosomal protein S6 kinase (rsk-1)
[Caenorhabditis elegans]
gi|7506916|pir||T24340 hypothetical protein T01H8.1b - Caenorhabditis
elegans
Length = 740
Score = 1417 bits (3667), Expect = 0.0
Identities = 717/740 (96%), Positives = 717/740 (96%)
Frame = -1
Query: 2223 MLILAXXXXXXXXXXEQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGK 2044
MLILA EQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGK
Sbjct: 1 MLILAEVEEFAENEIEQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGK 60
Query: 2043 VFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEG 1864
VFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEG
Sbjct: 61 VFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEG 120
Query: 1863 KLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILL 1684
KLYLILDFLRGGDLFTRLSKEVMFTEDDVKFY LGIVYRDLKPENILL
Sbjct: 121 KLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILL 180
Query: 1683 DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEM 1504
DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEM
Sbjct: 181 DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEM 240
Query: 1503 LTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEI 1324
LTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEI
Sbjct: 241 LTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEI 300
Query: 1323 KRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI 1144
KRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI
Sbjct: 301 KRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI 360
Query: 1143 FRGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATR 964
FRGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATR
Sbjct: 361 FRGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATR 420
Query: 963 RKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKL 784
RKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKL
Sbjct: 421 RKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKL 480
Query: 783 VNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGF 604
VNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGF
Sbjct: 481 VNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGF 540
Query: 603 AKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND 424
AKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND
Sbjct: 541 AKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND 600
Query: 423 TPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEA 244
TPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEA
Sbjct: 601 TPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEA 660
Query: 243 LPDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT 64
LPDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT
Sbjct: 661 LPDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT 720
Query: 63 KNVSANAWCVFFLQCRWLLS 4
KNVSANAWCVFFLQCRWLLS
Sbjct: 721 KNVSANAWCVFFLQCRWLLS 740
>gi|17508707|ref|NP_492319.1| ribosomal protein S6 kinase (rsk-1)
[Caenorhabditis elegans]
gi|7506915|pir||T23927 hypothetical protein T01H8.1a - Caenorhabditis
elegans
Length = 797
Score = 1404 bits (3635), Expect = 0.0
Identities = 707/720 (98%), Positives = 707/720 (98%)
Frame = -1
Query: 2163 KTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKV 1984
KTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKV
Sbjct: 78 KTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKV 137
Query: 1983 LKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK 1804
LKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK
Sbjct: 138 LKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK 197
Query: 1803 EVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDS 1624
EVMFTEDDVKFY LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDS
Sbjct: 198 EVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDS 257
Query: 1623 EKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL 1444
EKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL
Sbjct: 258 EKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL 317
Query: 1443 KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 1264
KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID
Sbjct: 318 KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 377
Query: 1263 PPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAK 1084
PPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAK
Sbjct: 378 PPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAK 437
Query: 1083 SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD 904
SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD
Sbjct: 438 SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD 497
Query: 903 ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLL 724
ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLL
Sbjct: 498 ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLL 557
Query: 723 NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF 544
NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF
Sbjct: 558 NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF 617
Query: 543 VAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV 364
VAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV
Sbjct: 618 VAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV 677
Query: 363 WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK 184
WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK
Sbjct: 678 WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK 737
Query: 183 VALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANAWCVFFLQCRWLLS 4
VALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANAWCVFFLQCRWLLS
Sbjct: 738 VALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANAWCVFFLQCRWLLS 797
>gi|33300393|emb|CAB02301.2| Hypothetical protein T01H8.1b
[Caenorhabditis elegans]
Length = 727
Score = 1385 bits (3585), Expect = 0.0
Identities = 704/727 (96%), Positives = 704/727 (96%)
Frame = -1
Query: 2223 MLILAXXXXXXXXXXEQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGK 2044
MLILA EQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGK
Sbjct: 1 MLILAEVEEFAENEIEQGEEKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGK 60
Query: 2043 VFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEG 1864
VFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEG
Sbjct: 61 VFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEG 120
Query: 1863 KLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILL 1684
KLYLILDFLRGGDLFTRLSKEVMFTEDDVKFY LGIVYRDLKPENILL
Sbjct: 121 KLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILL 180
Query: 1683 DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEM 1504
DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEM
Sbjct: 181 DADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEM 240
Query: 1503 LTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEI 1324
LTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEI
Sbjct: 241 LTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEI 300
Query: 1323 KRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI 1144
KRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI
Sbjct: 301 KRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEI 360
Query: 1143 FRGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATR 964
FRGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATR
Sbjct: 361 FRGFSFVSNAVMEERKLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATR 420
Query: 963 RKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKL 784
RKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKL
Sbjct: 421 RKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKL 480
Query: 783 VNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGF 604
VNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGF
Sbjct: 481 VNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGF 540
Query: 603 AKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND 424
AKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND
Sbjct: 541 AKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPND 600
Query: 423 TPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEA 244
TPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEA
Sbjct: 601 TPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEA 660
Query: 243 LPDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT 64
LPDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT
Sbjct: 661 LPDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT 720
Query: 63 KNVSANA 43
KNVSANA
Sbjct: 721 KNVSANA 727
>gi|45645188|sp|Q21734|KS6A_CAEEL Putative ribosomal protein S6 kinase
alpha
gi|33300394|emb|CAB02302.2| Hypothetical protein T01H8.1a
[Caenorhabditis elegans]
gi|33300451|emb|CAA99896.2| Hypothetical protein T01H8.1a
[Caenorhabditis elegans]
Length = 784
Score = 1373 bits (3553), Expect = 0.0
Identities = 694/707 (98%), Positives = 694/707 (98%)
Frame = -1
Query: 2163 KTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKV 1984
KTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKV
Sbjct: 78 KTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKV 137
Query: 1983 LKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK 1804
LKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK
Sbjct: 138 LKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSK 197
Query: 1803 EVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDS 1624
EVMFTEDDVKFY LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDS
Sbjct: 198 EVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDS 257
Query: 1623 EKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL 1444
EKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL
Sbjct: 258 EKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQIL 317
Query: 1443 KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 1264
KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID
Sbjct: 318 KAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEID 377
Query: 1263 PPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAK 1084
PPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAK
Sbjct: 378 PPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAK 437
Query: 1083 SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD 904
SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD
Sbjct: 438 SVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVD 497
Query: 903 ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLL 724
ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLL
Sbjct: 498 ILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLL 557
Query: 723 NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF 544
NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF
Sbjct: 558 NAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQF 617
Query: 543 VAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV 364
VAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV
Sbjct: 618 VAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPV 677
Query: 363 WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK 184
WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK
Sbjct: 678 WDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVK 737
Query: 183 VALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANA 43
VALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANA
Sbjct: 738 VALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANA 784
>gi|33300395|emb|CAE17938.1| Hypothetical protein T01H8.1c
[Caenorhabditis elegans]
gi|33300452|emb|CAE17895.1| Hypothetical protein T01H8.1c
[Caenorhabditis elegans]
Length = 745
Score = 1371 bits (3548), Expect = 0.0
Identities = 693/706 (98%), Positives = 693/706 (98%)
Frame = -1
Query: 2160 TDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
TDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL
Sbjct: 40 TDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 99
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
Sbjct: 100 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 159
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTEDDVKFY LGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE
Sbjct: 160 VMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 219
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK
Sbjct: 220 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 279
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP
Sbjct: 280 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 339
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 1081
PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS
Sbjct: 340 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 399
Query: 1080 VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI 901
VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI
Sbjct: 400 VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI 459
Query: 900 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 721
LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN
Sbjct: 460 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 519
Query: 720 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 541
AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV
Sbjct: 520 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 579
Query: 540 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 361
APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW
Sbjct: 580 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 639
Query: 360 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 181
DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV
Sbjct: 640 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 699
Query: 180 ALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANA 43
ALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANA
Sbjct: 700 ALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYTKNVSANA 745
>gi|39595602|emb|CAE67103.1| Hypothetical protein CBG12516
[Caenorhabditis briggsae]
Length = 807
Score = 1283 bits (3321), Expect = 0.0
Identities = 647/709 (91%), Positives = 675/709 (94%), Gaps = 1/709 (0%)
Frame = -1
Query: 2166 EKTDSSSETEIDIGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMK 1987
+K S+SETEIDIGDVRKCGEKAD +QFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMK
Sbjct: 76 KKESSASETEIDIGDVRKCGEKADRQQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMK 135
Query: 1986 VLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS 1807
VLKKATLK+RDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS
Sbjct: 136 VLKKATLKIRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLS 195
Query: 1806 KEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAID 1627
KEVMFTEDDVKFY LGIVYRDLKPENILLDADGHIKVTDFGLSKEAID
Sbjct: 196 KEVMFTEDDVKFYLAELTLALEHLHSLGIVYRDLKPENILLDADGHIKVTDFGLSKEAID 255
Query: 1626 SEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQI 1447
SEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTM QI
Sbjct: 256 SEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMNQI 315
Query: 1446 LKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEI 1267
LKAKLSMPHFLTQEAQSLLRALFKRNS NRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEI
Sbjct: 316 LKAKLSMPHFLTQEAQSLLRALFKRNSHNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEI 375
Query: 1266 DPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIA 1087
DPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV+EERKLI
Sbjct: 376 DPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVIEERKLIQ 435
Query: 1086 KSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEV 907
KS+RSVPTAKT+PFTDDYEILEKIGNGAHSVVHKCQMKAT R+YAVKIVKKAVFDATEEV
Sbjct: 436 KSIRSVPTAKTHPFTDDYEILEKIGNGAHSVVHKCQMKATPRRYAVKIVKKAVFDATEEV 495
Query: 906 DILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANL 727
DILLRHSH QF+VKLFDVYEDETAIYM+EELCEGGELLD+LVNK++LGSEKEVA++M+NL
Sbjct: 496 DILLRHSHQQFIVKLFDVYEDETAIYMVEELCEGGELLDRLVNKRALGSEKEVASLMSNL 555
Query: 726 LNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQ 547
L AVQYLHSQQVAHRDLTAANILFA KDGDP+SLRIVDFGFAKQSRAENGMLMTPCYTAQ
Sbjct: 556 LYAVQYLHSQQVAHRDLTAANILFASKDGDPNSLRIVDFGFAKQSRAENGMLMTPCYTAQ 615
Query: 546 FVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHP 367
FVAPEVLRKQGYDRSCDVWSLGVLLHTMLTG TPFAMGPNDTPDQILQRVGDGKI+MT P
Sbjct: 616 FVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGFTPFAMGPNDTPDQILQRVGDGKITMTQP 675
Query: 366 VWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNV 187
VWDTIS++AKDLV+KMLDVDPNRRVTAKQALQHKW G+KE+LPDRPIQ E +LDM +V
Sbjct: 676 VWDTISEDAKDLVKKMLDVDPNRRVTAKQALQHKWFGRKESLPDRPIQ-ENGEKLDMTDV 734
Query: 186 KVALEQTYKAIASAPSVQLRPVGSSALAKRRMKEILYANYT-KNVSANA 43
K AL+QTYKAI+SAPSV LRPVGSSALAKRRMK+ILYANYT KNVSANA
Sbjct: 735 KTALDQTYKAISSAPSVTLRPVGSSALAKRRMKDILYANYTKKNVSANA 783
>gi|125692|sp|P18652|K6AA_CHICK Ribosomal protein S6 kinase II alpha
(S6KII-alpha) (P90-RSK) (MAP kinase-activated protein
kinase 1) (MAPK-activated protein kinase 1) (MAPKAP
kinase 1) (MAPKAPK-1)
gi|86432|pir||A32571 ribosomal protein S6 kinase II (EC 2.7.1.-)
alpha chain homolog - chicken
gi|551556|gb|AAA21877.1| ribosomal protein S6 kinase
Length = 752
Score = 862 bits (2226), Expect = 0.0
Identities = 434/686 (63%), Positives = 527/686 (76%), Gaps = 6/686 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QFELLKVLGQGSFGKVFLVRK+ DS H+YAMKVLKKATLKVRDR RT
Sbjct: 68 VKEGSEKADPSQFELLKVLGQGSFGKVFLVRKITPPDSNHLYAMKVLKKATLKVRDRVRT 127
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+ILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+DVKFY
Sbjct: 128 KIERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 187
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSFCGTVEYM
Sbjct: 188 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 247
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NR+GHS +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP FL+ EA
Sbjct: 248 APEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSAEA 307
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLRALFKRN NRLG+GPDG EEIKRH F++ ID+ KL +EI PPFKPA+ D T
Sbjct: 308 QSLLRALFKRNPANRLGSGPDGAEEIKRHPFYSTIDWNKLYRREIKPPFKPAVGQPDDTF 367
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKL-----IAKSVRSVPTAK 1057
YFD EFT RTPKDSP +P SA H++FRGFSFV+ +ME+ K+ SV K
Sbjct: 368 YFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDSKVKPAQPPLHSVVQQLHGK 427
Query: 1056 TNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F+D Y + E IG G++SV +C K T +YAVK++ K+ D +EE++ILLR+ H
Sbjct: 428 NIQFSDGYVVKEAIGVGSYSVCKRCIHKTTNMEYAVKVIDKSKRDPSEEIEILLRYGQHP 487
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L DVY+D +Y++ EL GGELLDK++ +K SE+E ++++ + V+YLHSQ
Sbjct: 488 NIITLKDVYDDGKYVYLVTELMRGGELLDKILRQKFF-SEREASSVLHTICKTVEYLHSQ 546
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCYTA FVAPEVL++Q
Sbjct: 547 GVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQ 606
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD CD+WSLGVLL+TML GCTPFA GP+DTP++IL R+G GK S+ WDTISD AK
Sbjct: 607 GYDEGCDIWSLGVLLYTMLAGCTPFANGPSDTPEEILTRIGGGKFSVNGGNWDTISDVAK 666
Query: 336 DLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKA 157
DLV KML VDP++R+TAKQ LQH WI QK++LP Q+ D+Q VK A+ TY A
Sbjct: 667 DLVSKMLHVDPHQRLTAKQVLQHPWITQKDSLP-----QSQLNYQDVQLVKGAMAATYSA 721
Query: 156 I-ASAPSVQLRPVGSSALAKRRMKEI 82
+ +S PS QL+P+ SS LA+RR+K++
Sbjct: 722 LNSSKPSPQLKPIESSILAQRRVKKL 747
>gi|29294760|gb|AAH49076.1| Rps6ka1 protein [Mus musculus]
Length = 773
Score = 848 bits (2192), Expect = 0.0
Identities = 431/700 (61%), Positives = 530/700 (75%), Gaps = 8/700 (1%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D + EI I K G EKADP QFELLKVLGQGSFGKVFLVRKV DSGH+YAMKVL
Sbjct: 75 DEAILKEISITHHVKAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVL 134
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKATLKVRDR RTK+ER+ILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
Sbjct: 135 KKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 194
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID E
Sbjct: 195 VMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHE 254
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KK YSFCGTVEYMAPEV+NR+GH+ +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILK
Sbjct: 255 KKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILK 314
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ EAQSLLRALFKRN NRLG+GPDG EEIKRH F++ ID+ KL +EI P
Sbjct: 315 AKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKP 374
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE------R 1099
PFKPA++ D T YFD EFT RTP+DSP +P SA H++FRGFSFV+ +ME+
Sbjct: 375 PFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRTT 434
Query: 1098 KLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDA 919
+ SV K F+D Y + E IG G++SV +C KAT +YAVK++ K+ D
Sbjct: 435 QAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDP 494
Query: 918 TEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAI 739
+EE++ILLR+ H ++ L DVY+D +Y++ EL GGELLDK++ +K SE+E + +
Sbjct: 495 SEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFF-SEREASFV 553
Query: 738 MANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPC 559
+ + V+YLHSQ V HRDL +NIL+ + G+P LRI DFGFAKQ RAENG+LMTPC
Sbjct: 554 LHTISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPC 613
Query: 558 YTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKIS 379
YTA FVAPEVL++QGYD CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +
Sbjct: 614 YTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFT 673
Query: 378 MTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELD 199
++ W+T+S+ AKDLV KML VDP++R+TAKQ LQH WI QK+ LP Q+ D
Sbjct: 674 LSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLP-----QSQLSHQD 728
Query: 198 MQNVKVALEQTYKAI-ASAPSVQLRPVGSSALAKRRMKEI 82
+Q VK A+ TY A+ +S P+ QL+P+ SS LA+RR++++
Sbjct: 729 LQLVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKL 768
>gi|50730201|ref|XP_416804.1| PREDICTED: similar to ribosomal protein
S6 kinase 2 [Gallus gallus]
Length = 1153
Score = 847 bits (2189), Expect = 0.0
Identities = 431/700 (61%), Positives = 525/700 (74%), Gaps = 7/700 (1%)
Frame = -1
Query: 2172 GEEKTDSSSETEID----IGDVRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSG 2005
GE+ + +E EI V++ EKADP QFELLKVLGQGSFGKVFLV+K+ G D+
Sbjct: 449 GEDDINPQNEEEIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDAR 508
Query: 2004 HVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGD 1825
+YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD
Sbjct: 509 QLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGD 568
Query: 1824 LFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGL 1645
LFTRLSKEVMFTEDDVKFY LGI+YRDLKPENILLD +GHIK+TDFGL
Sbjct: 569 LFTRLSKEVMFTEDDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGL 628
Query: 1644 SKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRN 1465
SKE+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR
Sbjct: 629 SKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRK 688
Query: 1464 DTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVK 1285
+TMT ILKAKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH FF+KID+ K
Sbjct: 689 ETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHPFFSKIDWNK 748
Query: 1284 LLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVME 1105
L +EI PPFKPA + T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+ A +
Sbjct: 749 LYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAIASDD 808
Query: 1104 E-RKLIAKSVRSVPTAKTN--PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK 934
E + + V S+ N FTD YE+ E IG G++S+ +C KA+ +YAVKI+ K
Sbjct: 809 ESQSMQTVGVHSIVQLHRNSIQFTDGYEVKEDIGVGSYSICKRCVHKASNMEYAVKIIDK 868
Query: 933 AVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEK 754
+ D TEE++ILLR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K SE+
Sbjct: 869 SKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF-SER 927
Query: 753 EVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGM 574
E +A++ + V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+
Sbjct: 928 EASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGL 987
Query: 573 LMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVG 394
LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP+DTP++IL R+G
Sbjct: 988 LMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIG 1047
Query: 393 DGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQ 214
GK S++ W+T+SD AKDLV KML VDP++R+TA Q L H WI + LP + +
Sbjct: 1048 SGKFSLSGGYWNTVSDTAKDLVSKMLHVDPHQRLTAAQVLSHPWIVHCDQLPQYQLNRQD 1107
Query: 213 VGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
L VK A+ TY A+ S L PVG S LA+RR
Sbjct: 1108 APHL----VKGAMAATYSALNRNQSPVLEPVGRSTLAQRR 1143
>gi|47086473|ref|NP_997951.1| ribosomal protein S6 kinase polypeptide
3; id:ibd1103 [Danio rerio]
gi|28279650|gb|AAH45856.1| Ribosomal protein S6 kinase polypeptide 3
[Danio rerio]
Length = 732
Score = 845 bits (2184), Expect = 0.0
Identities = 430/694 (61%), Positives = 523/694 (74%), Gaps = 6/694 (0%)
Frame = -1
Query: 2157 DSSSETEIDIGD-VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D S EI I V++ EKADPRQFEL KVLGQGSFGKVFLV+K+ G D+G +YAMKVL
Sbjct: 34 DEGSVKEISITHHVKEGSEKADPRQFELRKVLGQGSFGKVFLVKKISGPDAGQLYAMKVL 93
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
Sbjct: 94 KKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 153
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGI+YRDLKPENILLD DGHI++TDFGLSKE+ID E
Sbjct: 154 VMFTEEDVKFYLAELALALDHLHGLGIIYRDLKPENILLDDDGHIELTDFGLSKESIDHE 213
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
K YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILK
Sbjct: 214 NKAYSFCGTVEYMAPEVVNRRGHTQSADWWSYGVLMFEMLTGALPFQGKDRKETMTMILK 273
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVE IKRH+FF +ID+ KL KE+ P
Sbjct: 274 AKLGMPQFLSPEAQSLLRNLFKRNPGNRLGAGPDGVEGIKRHSFFTRIDWNKLFRKEVPP 333
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 1081
PFKPA+ D T YFD EFT +TP+DSP +P SAN H++FRGFSFV+ V EE + +S
Sbjct: 334 PFKPAIKKPDDTFYFDSEFTAKTPRDSPGVPPSANAHQLFRGFSFVATGVEEESQSPIQS 393
Query: 1080 VRSVPT-----AKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT 916
++ + T FTD YE+ E IG G++SV +C K+T YAVKI+KK D T
Sbjct: 394 NINMSSILQSHRSTLQFTDAYEVKEDIGVGSYSVCKRCVQKSTGMDYAVKIIKKERRDPT 453
Query: 915 EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIM 736
EEV+ILLR+ H ++ L DV++D ++Y++ EL +GGELLDK++ +K SE+E +A++
Sbjct: 454 EEVEILLRYGQHPNIITLKDVFDDGRSVYLVTELMKGGELLDKILRQKFF-SEREASAVL 512
Query: 735 ANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 556
+ V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCY
Sbjct: 513 YTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCY 572
Query: 555 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 376
TA FVAPEVL+KQGYD +CD+WSLGVLL+TMLTG TPFA GP DTP++IL R+G GK S+
Sbjct: 573 TANFVAPEVLKKQGYDAACDIWSLGVLLYTMLTGFTPFANGPEDTPEEILARIGSGKFSL 632
Query: 375 THPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDM 196
T W+++S +AKDLV KML VDP++R+TA Q L+H WI K+ LP + + L
Sbjct: 633 TGGYWNSVSHDAKDLVSKMLHVDPHKRLTAAQVLRHPWIINKDQLPKYQLNRQDAPHL-- 690
Query: 195 QNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
VK A+ TY A+ S L PVG S LA+RR
Sbjct: 691 --VKGAMAATYSALNRNVSPVLDPVGCSTLAQRR 722
>gi|2117824|pir||I51901 ribosomal protein S6 kinase 2 (EC 2.7.1.-) 1 -
human
gi|292457|gb|AAC82497.1| ribosomal protein S6 kinase 1 [Homo sapiens]
gi|741749|prf||2008108A rsk HU-1 protein (ribosomal protein S6
kinase)
Length = 735
Score = 845 bits (2183), Expect = 0.0
Identities = 429/694 (61%), Positives = 526/694 (74%), Gaps = 8/694 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EI I K G EKADP FELLKVLGQGSFGKVFLVRKV DSGH+YAMKVLKKATLK
Sbjct: 43 EISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLK 102
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR RTK+ER+ILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 103 VRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 162
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSF
Sbjct: 163 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSF 222
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGTVEYMAPEV+NR+GHS +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP
Sbjct: 223 CGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMP 282
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLG+GPDG EEIKRH F++ ID+ KL +EI PPFKPA+
Sbjct: 283 QFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREITPPFKPAV 342
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE------RKLIAKS 1081
+ D T YFD EFT RTPKDSP +P SA H++FRGFSFV+ +ME+ + S
Sbjct: 343 AQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHS 402
Query: 1080 VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI 901
V K F+D Y + E IG G++S +C KAT +YAVK++ K+ D +EE++I
Sbjct: 403 VVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI 462
Query: 900 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 721
LLR+ H ++ L DVY+D +Y++ EL GGELLDK++ +K SE+E + ++ +
Sbjct: 463 LLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFF-SEREASFVLHTIGK 521
Query: 720 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 541
V+YLHSQ V HRDL +NIL+ + G+P LRI DFGFAKQ RAENG+LMTPCYTA FV
Sbjct: 522 TVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFV 581
Query: 540 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 361
APEVL++QGYD CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +++ W
Sbjct: 582 APEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW 641
Query: 360 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 181
+T+S+ AKDLV KML VDP++R+TAKQ LQH W+ QK+ LP Q+ D+Q VK
Sbjct: 642 NTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLP-----QSQLSHQDLQLVKG 696
Query: 180 ALEQTYKAI-ASAPSVQLRPVGSSALAKRRMKEI 82
A+ TY A+ +S P+ QL+P+ SS LA+RR++++
Sbjct: 697 AMAATYSALNSSKPTPQLKPIESSILAQRRVRKL 730
>gi|20149547|ref|NP_002944.2| ribosomal protein S6 kinase, 90kDa,
polypeptide 1; ribosomal protein S6 kinase, 90kD,
polypeptide 1; Ribosomal protein S6 kinase, 90kD, 1 [Homo
sapiens]
gi|20178306|sp|Q15418|K6A1_HUMAN Ribosomal protein S6 kinase alpha 1
(S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1)
(p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1)
gi|15929013|gb|AAH14966.1| Ribosomal protein S6 kinase, 90kDa,
polypeptide 1 [Homo sapiens]
Length = 735
Score = 845 bits (2183), Expect = 0.0
Identities = 429/694 (61%), Positives = 526/694 (74%), Gaps = 8/694 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EI I K G EKADP FELLKVLGQGSFGKVFLVRKV DSGH+YAMKVLKKATLK
Sbjct: 43 EISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVLKKATLK 102
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR RTK+ER+ILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 103 VRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 162
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSF
Sbjct: 163 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSF 222
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGTVEYMAPEV+NR+GHS +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP
Sbjct: 223 CGTVEYMAPEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMP 282
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLG+GPDG EEIKRH F++ ID+ KL +EI PPFKPA+
Sbjct: 283 QFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHVFYSTIDWNKLYRREIKPPFKPAV 342
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE------RKLIAKS 1081
+ D T YFD EFT RTPKDSP +P SA H++FRGFSFV+ +ME+ + S
Sbjct: 343 AQPDDTFYFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRAPQAPLHS 402
Query: 1080 VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI 901
V K F+D Y + E IG G++S +C KAT +YAVK++ K+ D +EE++I
Sbjct: 403 VVQQLHGKNLVFSDGYVVKETIGVGSYSECKRCVHKATNMEYAVKVIDKSKRDPSEEIEI 462
Query: 900 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 721
LLR+ H ++ L DVY+D +Y++ EL GGELLDK++ +K SE+E + ++ +
Sbjct: 463 LLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFF-SEREASFVLHTIGK 521
Query: 720 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 541
V+YLHSQ V HRDL +NIL+ + G+P LRI DFGFAKQ RAENG+LMTPCYTA FV
Sbjct: 522 TVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFV 581
Query: 540 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 361
APEVL++QGYD CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +++ W
Sbjct: 582 APEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFTLSGGNW 641
Query: 360 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 181
+T+S+ AKDLV KML VDP++R+TAKQ LQH W+ QK+ LP Q+ D+Q VK
Sbjct: 642 NTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWVTQKDKLP-----QSQLSHQDLQLVKG 696
Query: 180 ALEQTYKAI-ASAPSVQLRPVGSSALAKRRMKEI 82
A+ TY A+ +S P+ QL+P+ SS LA+RR++++
Sbjct: 697 AMAATYSALNSSKPTPQLKPIESSILAQRRVRKL 730
>gi|6537166|gb|AAF15553.1| Rsk-2 [Xenopus laevis]
Length = 737
Score = 843 bits (2178), Expect = 0.0
Identities = 430/699 (61%), Positives = 523/699 (74%), Gaps = 5/699 (0%)
Frame = -1
Query: 2175 QGEEKTDSSSETEIDIGD-VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHV 1999
+ E D + EI I V++ EKADP QFELLKVLGQGSFGKVFLVRK+ G D+G +
Sbjct: 34 EDNENNDEGNINEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVRKISGTDAGQL 93
Query: 1998 YAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLF 1819
YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLF
Sbjct: 94 YAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLF 153
Query: 1818 TRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSK 1639
TRLSKEVMFTE+DVK+Y LGI+YRDLKPENILLD +GHIK+TDFGLSK
Sbjct: 154 TRLSKEVMFTEEDVKYYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSK 213
Query: 1638 EAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDT 1459
E+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +T
Sbjct: 214 ESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKET 273
Query: 1458 MTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLL 1279
MT ILKAKL MP FLT EAQSLLR LFKRN NRLGAGPDGVEEIKRH FF ID+ KL
Sbjct: 274 MTMILKAKLGMPQFLTPEAQSLLRMLFKRNPTNRLGAGPDGVEEIKRHPFFVTIDWNKLF 333
Query: 1278 NKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEER 1099
+EI PPFKPA + T YFDPEFT +TPKDSP +PASAN H++FRGFSFV+ + +E
Sbjct: 334 RREIQPPFKPATGGPEDTFYFDPEFTAKTPKDSPGIPASANAHQLFRGFSFVAISSEDEN 393
Query: 1098 KLI-AKSVRSVPTAKTN--PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAV 928
+ + V ++ N FTD YE+ E IG G++S+ +C K T +YAVKI+ K+
Sbjct: 394 QAMQTVGVHAIVPLHRNSIQFTDGYELKEDIGVGSYSICKRCIHKGTNMEYAVKIIDKSK 453
Query: 927 FDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEV 748
D TEE++ILLR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K SE+E
Sbjct: 454 RDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYLVTELMKGGELLDKILRQKFF-SEREA 512
Query: 747 AAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLM 568
+A++ + +YLHSQ V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LM
Sbjct: 513 SAVLHTITKTAEYLHSQWVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLM 572
Query: 567 TPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDG 388
TPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP DTP++IL R+G G
Sbjct: 573 TPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPEDTPEEILARIGSG 632
Query: 387 KISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVG 208
K S++ W+++SD AKDLV KML VDP++R+TA Q L+H WI + LP + +
Sbjct: 633 KFSLSGGYWNSVSDIAKDLVSKMLHVDPHQRLTAAQVLKHPWIVHCDQLPQFQLNRQDAP 692
Query: 207 ELDMQNVKVALEQTYKAIASAP-SVQLRPVGSSALAKRR 94
L VK A+ TY A+ P S L PVG S LA+RR
Sbjct: 693 HL----VKGAMAATYSALNLNPMSPVLAPVGRSTLAQRR 727
>gi|13592065|ref|NP_112369.1| S6 protein kinase (Rsk-1) [Rattus
norvegicus]
gi|11132671|sp|Q63531|K6A1_RAT Ribosomal protein S6 kinase alpha 1
(S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1)
(p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1)
(MAP kinase-activated protein kinase 1a) (MAPKAPK1A)
gi|2117822|pir||A53300 ribosomal protein S6 kinase (EC 2.7.-.-) II -
rat
gi|206772|gb|AAA02872.1| S6 protein kinase
Length = 735
Score = 843 bits (2177), Expect = 0.0
Identities = 427/694 (61%), Positives = 526/694 (75%), Gaps = 8/694 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EI I K G EKADP FELLKVLGQGSFGKVFLVRKV D+GH+YAMKVLKKATLK
Sbjct: 43 EISITHHVKAGSEKADPSHFELLKVLGQGSFGKVFLVRKVTRPDNGHLYAMKVLKKATLK 102
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR RTK+ER+ILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 103 VRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 162
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSF
Sbjct: 163 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSF 222
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGTVEYMAPEV+NR+GH+ +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP
Sbjct: 223 CGTVEYMAPEVVNRQGHTHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMP 282
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLG+GPDG EEIKRH F++ ID+ KL +EI PPFKPA+
Sbjct: 283 QFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKPPFKPAV 342
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE------RKLIAKS 1081
+ D T YFD EFT RTP+DSP +P SA H++FRGFSFV+ +ME+ + S
Sbjct: 343 AQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDSKPRATQAPLHS 402
Query: 1080 VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI 901
V K F+D Y + E IG G++SV +C KAT +YAVK++ K+ D +EE++I
Sbjct: 403 VVQQLHGKNLVFSDGYIVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDPSEEIEI 462
Query: 900 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 721
LLR+ H ++ L DVY+D +Y++ EL GGELLDK++ +K SE+E + ++ +
Sbjct: 463 LLRYGQHPNIITLKDVYDDSKHVYLVTELMRGGELLDKILRQKFF-SEREASFVLYTISK 521
Query: 720 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 541
V+YLHSQ V HRDL +NIL+ + G+P LRI DFGFAKQ RAENG+LMTPCYTA FV
Sbjct: 522 TVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPCYTANFV 581
Query: 540 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 361
APEVL++QGYD CD+WSLGVLL+TML G TPFA GP+DTP++IL R+ GK +++ W
Sbjct: 582 APEVLKRQGYDEGCDIWSLGVLLYTMLAGYTPFANGPSDTPEEILTRISSGKFTLSGGNW 641
Query: 360 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 181
+T+S+ AKDLV KML VDP++R+TAKQ LQH WI QK+ LP Q+ D+Q VK
Sbjct: 642 NTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLP-----QSQLSHQDLQLVKG 696
Query: 180 ALEQTYKAIASA-PSVQLRPVGSSALAKRRMKEI 82
+ TY A++S+ P+ QL+P+ SS LA+RR++++
Sbjct: 697 GMAATYSALSSSKPTPQLKPIESSILAQRRVRKL 730
>gi|33354095|dbj|BAC81131.1| RPS6KA3 [Homo sapiens]
gi|33354097|dbj|BAC81132.1| RPS6KA3 [Pan troglodytes]
gi|33354099|dbj|BAC81133.1| RPS6KA3 [Pongo pygmaeus]
Length = 726
Score = 837 bits (2161), Expect = 0.0
Identities = 426/703 (60%), Positives = 526/703 (74%), Gaps = 10/703 (1%)
Frame = -1
Query: 2172 GEEKTDSSSETEIDIGD------VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRD 2011
GEE+ + +E E+ I + V++ EKADP QFELLKVLGQGSFGKVFLV+K+ G D
Sbjct: 20 GEEEINPQTE-EVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSD 78
Query: 2010 SGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRG 1831
+ +YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRG
Sbjct: 79 ARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRG 138
Query: 1830 GDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDF 1651
GDLFTRLSKEVMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDF
Sbjct: 139 GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDF 198
Query: 1650 GLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRD 1471
GLSKE+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+D
Sbjct: 199 GLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKD 258
Query: 1470 RNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDF 1291
R +TMT ILKAKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+
Sbjct: 259 RKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 318
Query: 1290 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV 1111
KL +EI PPFKPA + T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+
Sbjct: 319 NKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITS 378
Query: 1110 MEERKLI----AKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKI 943
+E + + S+ + FTD YE+ E IG G++SV +C KAT ++AVKI
Sbjct: 379 DDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKI 438
Query: 942 VKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLG 763
+ K+ D TEE++ILLR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K
Sbjct: 439 IDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF- 497
Query: 762 SEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAE 583
SE+E +A++ + V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAE
Sbjct: 498 SEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAE 557
Query: 582 NGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQ 403
NG+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP+DTP++IL
Sbjct: 558 NGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILA 617
Query: 402 RVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQ 223
R+G GK S++ W+++SD AKDLV KML VDP++R+TA L+H WI + LP +
Sbjct: 618 RIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLN 677
Query: 222 SEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
+ L VK A+ TY A+ S L PVG S LA+RR
Sbjct: 678 RQDAPHL----VKGAMAATYSALNRNQSPVLEPVGRSTLAQRR 716
>gi|33304069|gb|AAQ02542.1| ribosomal protein S6 kinase, 90kDa,
polypeptide 3 [synthetic construct]
Length = 741
Score = 837 bits (2161), Expect = 0.0
Identities = 426/703 (60%), Positives = 526/703 (74%), Gaps = 10/703 (1%)
Frame = -1
Query: 2172 GEEKTDSSSETEIDIGD------VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRD 2011
GEE+ + +E E+ I + V++ EKADP QFELLKVLGQGSFGKVFLV+K+ G D
Sbjct: 34 GEEEINPQTE-EVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSD 92
Query: 2010 SGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRG 1831
+ +YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRG
Sbjct: 93 ARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRG 152
Query: 1830 GDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDF 1651
GDLFTRLSKEVMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDF
Sbjct: 153 GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDF 212
Query: 1650 GLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRD 1471
GLSKE+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+D
Sbjct: 213 GLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKD 272
Query: 1470 RNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDF 1291
R +TMT ILKAKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+
Sbjct: 273 RKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 332
Query: 1290 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV 1111
KL +EI PPFKPA + T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+
Sbjct: 333 NKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITS 392
Query: 1110 MEERKLI----AKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKI 943
+E + + S+ + FTD YE+ E IG G++SV +C KAT ++AVKI
Sbjct: 393 DDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKI 452
Query: 942 VKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLG 763
+ K+ D TEE++ILLR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K
Sbjct: 453 IDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF- 511
Query: 762 SEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAE 583
SE+E +A++ + V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAE
Sbjct: 512 SEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAE 571
Query: 582 NGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQ 403
NG+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP+DTP++IL
Sbjct: 572 NGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILA 631
Query: 402 RVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQ 223
R+G GK S++ W+++SD AKDLV KML VDP++R+TA L+H WI + LP +
Sbjct: 632 RIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLN 691
Query: 222 SEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
+ L VK A+ TY A+ S L PVG S LA+RR
Sbjct: 692 RQDAPHL----VKGAMAATYSALNRNQSPVLEPVGRSTLAQRR 730
>gi|4759050|ref|NP_004577.1| ribosomal protein S6 kinase, 90kDa,
polypeptide 3; ribosomal protein S6 kinase, 90kD,
polypeptide 3 [Homo sapiens]
gi|1730070|sp|P51812|K6A3_HUMAN Ribosomal protein S6 kinase alpha 3
(S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3)
(p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
(Insulin-stimulated protein kinase 1) (ISPK-1)
gi|2117821|pir||I38556 ribosomal protein S6 kinase 2 (EC 2.7.1.-) 3 -
human
gi|475588|gb|AAA81952.1| insulin-stimulated protein kinase 1
Length = 740
Score = 837 bits (2161), Expect = 0.0
Identities = 426/703 (60%), Positives = 526/703 (74%), Gaps = 10/703 (1%)
Frame = -1
Query: 2172 GEEKTDSSSETEIDIGD------VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRD 2011
GEE+ + +E E+ I + V++ EKADP QFELLKVLGQGSFGKVFLV+K+ G D
Sbjct: 34 GEEEINPQTE-EVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSD 92
Query: 2010 SGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRG 1831
+ +YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRG
Sbjct: 93 ARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRG 152
Query: 1830 GDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDF 1651
GDLFTRLSKEVMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDF
Sbjct: 153 GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDF 212
Query: 1650 GLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRD 1471
GLSKE+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+D
Sbjct: 213 GLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKD 272
Query: 1470 RNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDF 1291
R +TMT ILKAKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+
Sbjct: 273 RKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 332
Query: 1290 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV 1111
KL +EI PPFKPA + T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+
Sbjct: 333 NKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITS 392
Query: 1110 MEERKLI----AKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKI 943
+E + + S+ + FTD YE+ E IG G++SV +C KAT ++AVKI
Sbjct: 393 DDESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKI 452
Query: 942 VKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLG 763
+ K+ D TEE++ILLR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K
Sbjct: 453 IDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF- 511
Query: 762 SEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAE 583
SE+E +A++ + V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAE
Sbjct: 512 SEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAE 571
Query: 582 NGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQ 403
NG+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP+DTP++IL
Sbjct: 572 NGLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILA 631
Query: 402 RVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQ 223
R+G GK S++ W+++SD AKDLV KML VDP++R+TA L+H WI + LP +
Sbjct: 632 RIGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLN 691
Query: 222 SEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
+ L VK A+ TY A+ S L PVG S LA+RR
Sbjct: 692 RQDAPHL----VKGAMAATYSALNRNQSPVLEPVGRSTLAQRR 730
>gi|22507357|ref|NP_683747.1| ribosomal protein S6 kinase polypeptide
3; ribosomal protein S6 kinase 2 [Mus musculus]
gi|29337212|sp|P18654|K6A3_MOUSE Ribosomal protein S6 kinase alpha 3
(S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3)
(p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
(MAP kinase-activated protein kinase 1b) (MAPKAPK1B)
gi|21280793|gb|AAM00022.1| ribosomal protein S6 kinase 2 [Mus
musculus]
Length = 740
Score = 837 bits (2161), Expect = 0.0
Identities = 428/702 (60%), Positives = 525/702 (73%), Gaps = 9/702 (1%)
Frame = -1
Query: 2172 GEEK----TDSSSETEIDIGD-VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDS 2008
GEE+ T+ S EI I V++ EKADP QFELLKVLGQGSFGKVFLV+K+ G D+
Sbjct: 34 GEEEINPQTEEGSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSDA 93
Query: 2007 GHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGG 1828
+YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGG
Sbjct: 94 RQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGG 153
Query: 1827 DLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFG 1648
DLFTRLSKEVMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDFG
Sbjct: 154 DLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFG 213
Query: 1647 LSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDR 1468
LSKE+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR
Sbjct: 214 LSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDR 273
Query: 1467 NDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFV 1288
+TMT ILKAKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+
Sbjct: 274 KETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWN 333
Query: 1287 KLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVM 1108
KL +EI PPFKPA + T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+
Sbjct: 334 KLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSD 393
Query: 1107 EERKLI----AKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIV 940
+E + + S+ + FTD YE+ E IG G++SV +C KAT ++AVKI+
Sbjct: 394 DESQAMQTVGVHSIVQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKII 453
Query: 939 KKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGS 760
K+ D TEE++ILLR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K S
Sbjct: 454 DKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF-S 512
Query: 759 EKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAEN 580
E+E +A++ + V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAEN
Sbjct: 513 EREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAEN 572
Query: 579 GMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQR 400
G+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP+DTP++IL R
Sbjct: 573 GLLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILAR 632
Query: 399 VGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQS 220
+G GK S++ W+++SD AKDLV KML VDP++R+TA L+H WI + LP +
Sbjct: 633 IGSGKFSLSGGYWNSVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNR 692
Query: 219 EQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
+ L VK A+ TY A+ S L PVG S LA+RR
Sbjct: 693 QDAPHL----VKGAMAATYSALNRNQSPVLEPVGRSTLAQRR 730
>gi|6755374|ref|NP_035429.1| ribosomal protein S6 kinase, polypeptide
2; ribosomal protein S6 kinase, 90kD, polypeptide 2 [Mus
musculus]
gi|20897181|ref|XP_123003.1| similar to Ribosomal protein S6 kinase
alpha 2 (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase
2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
[Mus musculus]
gi|11133183|sp|Q9WUT3|K6A2_MOUSE Ribosomal protein S6 kinase alpha 2
(S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2)
(p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
(Protein-tyrosine kinase Mpk-9) (MAP kinase-activated
protein kinase 1c) (MAPKAPK1C)
gi|5019544|emb|CAB44492.1| ribosomal protein S6 kinase 3 [Mus
musculus]
gi|27696717|gb|AAH43064.1| Ribosomal protein S6 kinase, polypeptide 2
[Mus musculus]
gi|29835158|gb|AAH51079.1| Ribosomal protein S6 kinase, polypeptide 2
[Mus musculus]
gi|34785208|gb|AAH56946.1| Ribosomal protein S6 kinase, polypeptide 2
[Mus musculus]
Length = 733
Score = 829 bits (2141), Expect = 0.0
Identities = 426/695 (61%), Positives = 521/695 (74%), Gaps = 13/695 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI + K G EKADP QFELLKVLGQGS+GKVFLVRKV G D+G +YAMKVLKKATLK
Sbjct: 40 EIDISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLK 99
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 100 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 159
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEA D +K+ YSF
Sbjct: 160 DVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSF 219
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 220 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 279
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ KL KEI PPFKPA+
Sbjct: 280 QFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAV 339
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E S + VP
Sbjct: 340 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLVQE-----PSQQDVPK 394
Query: 1062 AKTNP-----------FTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT 916
A +P FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +
Sbjct: 395 APIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPS 454
Query: 915 EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIM 736
EE++ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++
Sbjct: 455 EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCF-SEREASDVL 513
Query: 735 ANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 556
+ + YLHSQ V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCY
Sbjct: 514 YTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCY 573
Query: 555 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 376
TA FVAPEVL++QGYD +CDVWSLG+LL+TML G TPFA GP+DTP++IL R+G GK ++
Sbjct: 574 TANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633
Query: 375 THPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDM 196
+ WD+ISD AKD+V KML VDP +R+TA Q L+H WI +E L Q+ D+
Sbjct: 634 SGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYL-----SQNQLSRQDV 688
Query: 195 QNVKVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
VK A+ TY A+ P +L PV SS+LA+RR
Sbjct: 689 HLVKGAMAATYFALNRTPQAPRLEPVLSSSLAQRR 723
>gi|33243964|gb|AAH55331.1| Ribosomal protein S6 kinase, polypeptide 2
[Mus musculus]
Length = 733
Score = 827 bits (2137), Expect = 0.0
Identities = 425/695 (61%), Positives = 520/695 (74%), Gaps = 13/695 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI + K G EKADP QFELLKVLGQGS+GKVFLVRKV G D+G +Y MKVLKKATLK
Sbjct: 40 EIDISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYTMKVLKKATLK 99
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 100 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 159
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEA D +K+ YSF
Sbjct: 160 DVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSF 219
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 220 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 279
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ KL KEI PPFKPA+
Sbjct: 280 QFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAV 339
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E S + VP
Sbjct: 340 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLVQE-----PSQQDVPK 394
Query: 1062 AKTNP-----------FTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT 916
A +P FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +
Sbjct: 395 APIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPS 454
Query: 915 EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIM 736
EE++ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++
Sbjct: 455 EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCF-SEREASDVL 513
Query: 735 ANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 556
+ + YLHSQ V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCY
Sbjct: 514 YTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCY 573
Query: 555 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 376
TA FVAPEVL++QGYD +CDVWSLG+LL+TML G TPFA GP+DTP++IL R+G GK ++
Sbjct: 574 TANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633
Query: 375 THPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDM 196
+ WD+ISD AKD+V KML VDP +R+TA Q L+H WI +E L Q+ D+
Sbjct: 634 SGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYL-----SQNQLSRQDV 688
Query: 195 QNVKVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
VK A+ TY A+ P +L PV SS+LA+RR
Sbjct: 689 HLVKGAMAATYFALNRTPQAPRLEPVLSSSLAQRR 723
>gi|12860267|dbj|BAB31901.1| unnamed protein product [Mus musculus]
Length = 733
Score = 827 bits (2137), Expect = 0.0
Identities = 425/695 (61%), Positives = 521/695 (74%), Gaps = 13/695 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI + K G EKADP QFELLKVLGQGS+G+VFLVRKV G D+G +YAMKVLKKATLK
Sbjct: 40 EIDISNHVKEGFEKADPSQFELLKVLGQGSYGEVFLVRKVTGSDAGQLYAMKVLKKATLK 99
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 100 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 159
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEA D +K+ YSF
Sbjct: 160 DVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSF 219
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 220 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 279
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ KL KEI PPFKPA+
Sbjct: 280 QFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAV 339
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E S + VP
Sbjct: 340 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLVQE-----PSQQDVPK 394
Query: 1062 AKTNP-----------FTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT 916
A +P FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +
Sbjct: 395 APIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPS 454
Query: 915 EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIM 736
EE++ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++
Sbjct: 455 EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCF-SEREASDVL 513
Query: 735 ANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 556
+ + YLHSQ V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCY
Sbjct: 514 YTIARTMDYLHSQGVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCY 573
Query: 555 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 376
TA FVAPEVL++QGYD +CDVWSLG+LL+TML G TPFA GP+DTP++IL R+G GK ++
Sbjct: 574 TANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYAL 633
Query: 375 THPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDM 196
+ WD+ISD AKD+V KML VDP +R+TA Q L+H WI +E L Q+ D+
Sbjct: 634 SGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYL-----SQNQLSRQDV 688
Query: 195 QNVKVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
VK A+ TY A+ P +L PV SS+LA+RR
Sbjct: 689 HLVKGAMAATYFALNRTPQAPRLEPVLSSSLAQRR 723
>gi|49256532|gb|AAH71102.1| Unknown (protein for MGC:81220) [Xenopus
laevis]
Length = 733
Score = 825 bits (2132), Expect = 0.0
Identities = 414/685 (60%), Positives = 520/685 (75%), Gaps = 5/685 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKAD F LLKVLGQGSFGKVFLVRK+ D+ +YAMKVLKKATLKVRDR RT
Sbjct: 50 VKEGAEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRT 109
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+ILA + HPF+V+LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+DVKFY
Sbjct: 110 KMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 169
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSFCGTVEYM
Sbjct: 170 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NR+GHS AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP FL+ EA
Sbjct: 230 APEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEA 289
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLRALFKRN+ NRLG+G +G EE+KRH FF+ ID+ KL +E+ PPFKP+++ D T
Sbjct: 290 QSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPPFKPSVTQPDDTY 349
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE--RKLIAKSVRSVPT--AKT 1054
YFD EFT RTPKDSP +P SA H++FRGFSFV+ ++EE +K + V SVP +K
Sbjct: 350 YFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPVLVEEDAKKTSSPPVLSVPKTHSKN 409
Query: 1053 NPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQF 874
FTD Y + E IG G++SV +C K T +YAVK++ K+ D +EE++IL R+ H
Sbjct: 410 VLFTDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKSKRDPSEEIEILRRYGQHPN 469
Query: 873 VVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQ 694
++ L DVYE+ +IY++ EL GGELLD+++ +K SE+E +++ + V+YLHSQ
Sbjct: 470 IITLKDVYEECNSIYLVTELMRGGELLDRILRQKFF-SEREACSVLFTVCKTVEYLHSQG 528
Query: 693 VAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQG 514
V HRDL +NIL+ + GDP S+RI DFGF+KQ RAENG+LMTPCYTA FVAPEVL++QG
Sbjct: 529 VVHRDLKPSNILYVDESGDPESIRICDFGFSKQLRAENGLLMTPCYTANFVAPEVLKRQG 588
Query: 513 YDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKD 334
YD CD+WSLG+LL+TML G TPFA GP DTP++IL R+G GK ++ W+T+S AKD
Sbjct: 589 YDEGCDIWSLGILLYTMLAGYTPFANGPGDTPEEILARIGSGKFTLRGGNWNTVSAAAKD 648
Query: 333 LVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKAI 154
LV +ML VDP++R+ AKQ LQH+WI +++ LP Q+ D+ VK A+ TY A+
Sbjct: 649 LVSRMLHVDPHQRLNAKQVLQHEWITKRDMLP-----QSQLNRQDVHLVKGAMAATYSAL 703
Query: 153 -ASAPSVQLRPVGSSALAKRRMKEI 82
+S P+ QL+P+ SS LA+RR+K++
Sbjct: 704 NSSKPTPQLQPIKSSVLAQRRVKKL 728
>gi|13676454|dbj|BAB41150.1| hypothetical protein [Macaca
fascicularis]
Length = 758
Score = 825 bits (2131), Expect = 0.0
Identities = 420/690 (60%), Positives = 517/690 (74%), Gaps = 8/690 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI K G EKADP QFELLKVLGQGS+GKVFLVRKV+G D+G +YAMKVLKKATLK
Sbjct: 65 EIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLK 124
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 125 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 184
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID +K+ YSF
Sbjct: 185 DVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSF 244
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 245 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 304
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ KL KEI PPFKPA+
Sbjct: 305 QFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNKLFRKEIKPPFKPAV 364
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE------RKLIAKS 1081
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E K+
Sbjct: 365 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPSQQDLHKVAVHP 424
Query: 1080 VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDI 901
+ FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +EE++I
Sbjct: 425 IVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEIEI 484
Query: 900 LLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLN 721
LLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++ +
Sbjct: 485 LLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILQQRYF-SEREASDVLCTITK 543
Query: 720 AVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFV 541
+ YLHSQ V HRDL +NIL+ + G P S+R+ DFGFAKQ RA NG+LMTPCYTA FV
Sbjct: 544 TMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTANFV 603
Query: 540 APEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVW 361
APEVL++QGYD +CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +++ W
Sbjct: 604 APEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNW 663
Query: 360 DTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKV 181
D+ISD AKD+V KML VDP++R+TA Q L+H W+ +E L Q+ D+ VK
Sbjct: 664 DSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYL-----SQNQLSRQDVHLVKC 718
Query: 180 ALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
A+ TY A+ AP +L PV SS LA+RR
Sbjct: 719 AMAATYFALNRAPQAPRLEPVLSSNLAQRR 748
>gi|25005142|gb|AAN71007.1| ribosomal protein S6 kinase [Mus musculus]
Length = 708
Score = 822 bits (2122), Expect = 0.0
Identities = 426/703 (60%), Positives = 521/703 (73%), Gaps = 21/703 (2%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI + K G EKADP QFELLKVLGQGS+GKVFLVRKV G D+G +YAMKVLKKATLK
Sbjct: 7 EIDISNHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLK 66
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 67 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 126
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEA D +K+ YSF
Sbjct: 127 DVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEATDHDKRAYSF 186
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 187 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 246
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ KL KEI PPFKPA+
Sbjct: 247 QFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAV 306
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E S + VP
Sbjct: 307 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLVQE-----PSQQDVPK 361
Query: 1062 AKTNP-----------FTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT 916
A +P FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +
Sbjct: 362 APIHPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPS 421
Query: 915 EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIM 736
EE++ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++
Sbjct: 422 EEIEILLRYGQHPNIITLKDVYDDGKYVYLVMELMRGGELLDRILRQRCF-SEREASDVL 480
Query: 735 ANLLNAVQYLHSQ--------QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAEN 580
+ + YLHSQ V HRDL +NIL+ + G+P S+RI DFGFAKQ RAEN
Sbjct: 481 YTIARTMDYLHSQGVGLPALPVVVHRDLKPSNILYMDESGNPESIRICDFGFAKQLRAEN 540
Query: 579 GMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQR 400
G+LMTPCYTA FVAPEVL++QGYD +CDVWSLG+LL+TML G TPFA GP+DTP++IL R
Sbjct: 541 GLLMTPCYTANFVAPEVLKRQGYDAACDVWSLGILLYTMLAGFTPFANGPDDTPEEILAR 600
Query: 399 VGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQS 220
+G GK +++ WD+ISD AKD+V KML VDP +R+TA Q L+H WI +E L
Sbjct: 601 IGSGKYALSGGNWDSISDAAKDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYL-----SQ 655
Query: 219 EQVGELDMQNVKVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
Q+ D+ VK A+ TY A+ P +L PV SS+LA+RR
Sbjct: 656 NQLSRQDVHLVKGAMAATYFALNRTPQAPRLEPVLSSSLAQRR 698
>gi|6166243|sp|Q15349|K6A2_HUMAN Ribosomal protein S6 kinase alpha 2
(S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2)
(p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
gi|2117823|pir||A57459 ribosomal protein S6 kinase 2 (EC 2.7.1.-) 2 -
human
gi|1033033|emb|CAA59427.1| ribosomal S6 kinase [Homo sapiens]
Length = 733
Score = 821 bits (2120), Expect = 0.0
Identities = 420/692 (60%), Positives = 516/692 (73%), Gaps = 10/692 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI K G EKADP QFELLKVLGQGS+GKVFLVRKV+G D+G +YAMKVLKKATLK
Sbjct: 40 EIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLK 99
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 100 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 159
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID +K+ YSF
Sbjct: 160 DVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSF 219
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 220 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 279
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ L KEI PPFKPAL
Sbjct: 280 QFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAL 339
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E + + VP
Sbjct: 340 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPS--QQDLHKVPV 397
Query: 1062 --------AKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEV 907
FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +EE+
Sbjct: 398 HPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEI 457
Query: 906 DILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANL 727
+ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++ +
Sbjct: 458 EILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYF-SEREASDVLCTI 516
Query: 726 LNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQ 547
+ YLHSQ V HRDL +NIL+ + G P S+R+ DFGFAKQ RA NG+LMTPCYTA
Sbjct: 517 TKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTAN 576
Query: 546 FVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHP 367
FVAPEVL++QGYD +CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +++
Sbjct: 577 FVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGG 636
Query: 366 VWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNV 187
WD+ISD AKD+V KML VDP++R+TA Q L+H W+ +E L Q+ D+ V
Sbjct: 637 NWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYL-----SPNQLSRQDVHLV 691
Query: 186 KVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
K A+ TY A+ P +L PV SS LA+RR
Sbjct: 692 KGAMAATYFALNRTPQAPRLEPVLSSNLAQRR 723
>gi|6677811|ref|NP_033123.1| ribosomal protein S6 kinase polypeptide 1
[Mus musculus]
gi|125690|sp|P18653|K6A1_MOUSE Ribosomal protein S6 kinase alpha 1
(S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1)
(p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1)
(MAP kinase-activated protein kinase 1a) (MAPKAPK1A)
gi|91276|pir||B32571 ribosomal protein S6 kinase II (EC 2.7.1.-)
alpha chain homolog (clone Mu6A) - mouse
gi|556322|gb|AAA50300.1| ribosomal protein S6 kinase
Length = 724
Score = 820 bits (2118), Expect = 0.0
Identities = 421/700 (60%), Positives = 520/700 (74%), Gaps = 8/700 (1%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D + EI I K G EKADP QFELLKVLGQGSFGKVFLVRKV DSGH+YAMKVL
Sbjct: 37 DEAILKEISITHHVKAGSEKADPSQFELLKVLGQGSFGKVFLVRKVTRPDSGHLYAMKVL 96
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKATLKVRDR RTK+ER+ILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
Sbjct: 97 KKATLKVRDRVRTKMERDILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 156
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID E
Sbjct: 157 VMFTEEDVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHE 216
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KK YSFCGTVEYMAPEV+NR+GH+ +AD+WS GVLM G+DR +TMT ILK
Sbjct: 217 KKAYSFCGTVEYMAPEVVNRQGHTHSADWWSYGVLM-----------GKDRKETMTLILK 265
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ EAQSLLRALFKRN NRLG+GPDG EEIKRH F++ ID+ KL +EI P
Sbjct: 266 AKLGMPQFLSTEAQSLLRALFKRNPANRLGSGPDGAEEIKRHIFYSTIDWNKLYRREIKP 325
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE------R 1099
PFKPA++ D T YFD EFT RTP+DSP +P SA H++FRGFSFV+ +ME+
Sbjct: 326 PFKPAVAQPDDTFYFDTEFTSRTPRDSPGIPPSAGAHQLFRGFSFVATGLMEDDGKPRTT 385
Query: 1098 KLIAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDA 919
+ SV K F+D Y + E IG G++SV +C KAT +YAVK++ K+ D
Sbjct: 386 QAPLHSVVQQLHGKNLVFSDGYVVKETIGVGSYSVCKRCVHKATNMEYAVKVIDKSKRDP 445
Query: 918 TEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAI 739
+EE++ILLR+ H ++ L DVY+D +Y++ EL GGELLDK++ +K SE+E + +
Sbjct: 446 SEEIEILLRYGQHPNIITLKDVYDDGKHVYLVTELMRGGELLDKILRQKFF-SEREASFV 504
Query: 738 MANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPC 559
+ + V+YLHSQ V HRDL +NIL+ + G+P LRI DFGFAKQ RAENG+LMTPC
Sbjct: 505 LHTISKTVEYLHSQGVVHRDLKPSNILYVDESGNPECLRICDFGFAKQLRAENGLLMTPC 564
Query: 558 YTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKIS 379
YTA FVAPEVL++QGYD CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +
Sbjct: 565 YTANFVAPEVLKRQGYDEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRIGSGKFT 624
Query: 378 MTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELD 199
++ W+T+S+ AKDLV KML VDP++R+TAKQ LQH WI QK+ LP Q+ D
Sbjct: 625 LSGGNWNTVSETAKDLVSKMLHVDPHQRLTAKQVLQHPWITQKDKLP-----QSQLSHQD 679
Query: 198 MQNVKVALEQTYKAI-ASAPSVQLRPVGSSALAKRRMKEI 82
+Q VK A+ TY A+ +S P+ QL+P+ SS LA+RR++++
Sbjct: 680 LQLVKGAMAATYSALNSSKPTPQLKPIESSILAQRRVRKL 719
>gi|19923570|ref|NP_066958.2| ribosomal protein S6 kinase, 90kDa,
polypeptide 2; ribosomal protein S6 kinase, 90kD,
polypeptide 2; Ribosomal protein S6 kinase, 90kD, 2 [Homo
sapiens]
gi|12803119|gb|AAH02363.1| Ribosomal protein S6 kinase, 90kDa,
polypeptide 2 [Homo sapiens]
Length = 733
Score = 820 bits (2117), Expect = 0.0
Identities = 419/692 (60%), Positives = 516/692 (74%), Gaps = 10/692 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI K G EKADP QFELLKVLGQGS+GKVFLVRKV+G D+G +YAMKVLKKATLK
Sbjct: 40 EIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLK 99
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 100 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 159
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID +K+ YSF
Sbjct: 160 DVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSF 219
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 220 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 279
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ L KEI PPFKPA+
Sbjct: 280 QFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAV 339
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E + + VP
Sbjct: 340 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPS--QQDLHKVPV 397
Query: 1062 --------AKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEV 907
FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +EE+
Sbjct: 398 HPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEI 457
Query: 906 DILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANL 727
+ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ SE+E + ++ +
Sbjct: 458 EILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYF-SEREASDVLCTI 516
Query: 726 LNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQ 547
+ YLHSQ V HRDL +NIL+ + G P S+R+ DFGFAKQ RA NG+LMTPCYTA
Sbjct: 517 TKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTAN 576
Query: 546 FVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHP 367
FVAPEVL++QGYD +CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +++
Sbjct: 577 FVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGG 636
Query: 366 VWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNV 187
WD+ISD AKD+V KML VDP++R+TA Q L+H W+ +E L Q+ D+ V
Sbjct: 637 NWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYL-----SPNQLSRQDVHLV 691
Query: 186 KVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
K A+ TY A+ P +L PV SS LA+RR
Sbjct: 692 KGAMAATYFALNRTPQAPRLEPVLSSNLAQRR 723
>gi|13605770|gb|AAK32877.1| 90-kDa ribosomal protein S6 kinase [Rana
dybowskii]
Length = 733
Score = 819 bits (2116), Expect = 0.0
Identities = 412/684 (60%), Positives = 515/684 (75%), Gaps = 4/684 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKAD F LLKVLGQGSFGKVFLVRK+ D+ +YAMKVLKKATLKVRDR RT
Sbjct: 51 VKEGSEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDNNQLYAMKVLKKATLKVRDRVRT 110
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+ILA + HPF+V+LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+DVKFY
Sbjct: 111 KMERDILAEVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 170
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGI+YRDLKPENILLD +GHIK+TDFGLSKE+ID EKK YSFCGTVEYM
Sbjct: 171 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYM 230
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NR+GHS +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP FL+ EA
Sbjct: 231 APEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSSEA 290
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
Q LLR+LFKRN NRLG+G DG EE+KRH+FF+ ID+ KL +EI PPFKPA+S + T
Sbjct: 291 QGLLRSLFKRNPANRLGSGIDGAEELKRHSFFSTIDWNKLYRREISPPFKPAVSQPEDTY 350
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV-MEERKLIAKSVRSVPTA--KTN 1051
YFD EFT RTPKDSP +P SA H++FRGFSFV+ E+R SVP K
Sbjct: 351 YFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPPFGGEDRPSSTSPSLSVPKMLNKNV 410
Query: 1050 PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQFV 871
FTD Y + E IG G++SV +C K T +YAVKI+ K+ D +EE++IL R+ H +
Sbjct: 411 AFTDVYTLRESIGVGSYSVCKRCVHKGTNMEYAVKIIDKSKKDPSEEIEILRRYGQHPNI 470
Query: 870 VKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQV 691
+ L DVYE+ ++Y++ +L GGELLD+++ +K SE+E A++ + V+YLHSQ V
Sbjct: 471 IALKDVYEEGNSVYLVTDLMRGGELLDRILRQKFF-SEREACAVLLTMCKTVEYLHSQGV 529
Query: 690 AHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGY 511
+RDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCYTA FVAPEVL++QGY
Sbjct: 530 VNRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGY 589
Query: 510 DRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDL 331
D CD+WSLG+LL+TML G TPFA GP DTPD+IL R+G GK ++ W+T+SD AKDL
Sbjct: 590 DEGCDIWSLGILLYTMLAGYTPFANGPEDTPDEILARIGSGKFTLKGGNWNTVSDSAKDL 649
Query: 330 VRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKAI- 154
V +ML VDP+RR+TA+Q + H+WI +++ LP + + D Q VK A+ TY A+
Sbjct: 650 VSRMLHVDPHRRLTARQVMHHEWITKRDLLPQSHLNRQ-----DAQLVKGAMVATYSALN 704
Query: 153 ASAPSVQLRPVGSSALAKRRMKEI 82
+S P+ QL+P+ SS LA+RR+K++
Sbjct: 705 SSKPTPQLQPIKSSILAQRRVKKL 728
>gi|33303975|gb|AAQ02495.1| ribosomal protein S6 kinase, 90kDa,
polypeptide 2 [synthetic construct]
Length = 734
Score = 818 bits (2113), Expect = 0.0
Identities = 418/692 (60%), Positives = 516/692 (74%), Gaps = 10/692 (1%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI K G EKADP QFELLKVLGQGS+GKVFLVRKV+G D+G +YAMKVLKKATLK
Sbjct: 40 EIDISHHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVKGSDAGQLYAMKVLKKATLK 99
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 100 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 159
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID +K+ YSF
Sbjct: 160 DVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSF 219
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 220 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 279
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ L KEI PPFKPA+
Sbjct: 280 QFLSGEAQSLLRALFKRNPCNRLGAGIDGVEEIKRHPFFVTIDWNTLYRKEIKPPFKPAV 339
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPT 1063
+ T +FDPEFT RTP DSP +P SAN H +FRGFSFV++++++E + + VP
Sbjct: 340 GRPEDTFHFDPEFTARTPTDSPGVPPSANAHHLFRGFSFVASSLIQEPS--QQDLHKVPV 397
Query: 1062 --------AKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEV 907
FTD YEI E IG G++SV +C KAT +YAVKI+ K+ D +EE+
Sbjct: 398 HPIVQQLHGNNIHFTDGYEIKEDIGVGSYSVCKRCVHKATDTEYAVKIIDKSKRDPSEEI 457
Query: 906 DILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANL 727
+ILLR+ H ++ L DVY+D +Y++ EL GGELLD+++ ++ S++E + ++ +
Sbjct: 458 EILLRYGQHPNIITLKDVYDDGKFVYLVMELMRGGELLDRILRQRYF-SKREASDVLCTI 516
Query: 726 LNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQ 547
+ YLHSQ V HRDL +NIL+ + G P S+R+ DFGFAKQ RA NG+LMTPCYTA
Sbjct: 517 TKTMDYLHSQGVVHRDLKPSNILYRDESGSPESIRVCDFGFAKQLRAGNGLLMTPCYTAN 576
Query: 546 FVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHP 367
FVAPEVL++QGYD +CD+WSLG+LL+TML G TPFA GP+DTP++IL R+G GK +++
Sbjct: 577 FVAPEVLKRQGYDAACDIWSLGILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGG 636
Query: 366 VWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNV 187
WD+ISD AKD+V KML VDP++R+TA Q L+H W+ +E L Q+ D+ V
Sbjct: 637 NWDSISDAAKDVVSKMLHVDPHQRLTAMQVLKHPWVVNREYL-----SPNQLSRQDVHLV 691
Query: 186 KVALEQTYKAIASAPSV-QLRPVGSSALAKRR 94
K A+ TY A+ P +L PV SS LA+RR
Sbjct: 692 KGAMAATYFALNRTPQAPRLEPVLSSNLAQRR 723
>gi|125693|sp|P10665|K6AA_XENLA Ribosomal protein S6 kinase II alpha
(S6KII-alpha) (P90-RSK) (MAP kinase-activated protein
kinase 1) (MAPK-activated protein kinase 1) (MAPKAP
kinase 1) (MAPKAPK-1)
gi|85847|pir||B30001 ribosomal protein S6 kinase (EC 2.7.1.-) II
alpha chain - African clawed frog
gi|214787|gb|AAA49958.1| S6 kinase II
gi|50414706|gb|AAH77262.1| Unknown (protein for MGC:79981) [Xenopus
laevis]
Length = 733
Score = 814 bits (2103), Expect = 0.0
Identities = 412/685 (60%), Positives = 517/685 (75%), Gaps = 5/685 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKAD F LLKVLGQGSFGKVFLVRK+ D+ +YAMKVLKKATLKVRDR RT
Sbjct: 50 VKEGSEKADQSDFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRT 109
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+ILA + HPF+V+LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+DVKFY
Sbjct: 110 KMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 169
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSFCGTVEYM
Sbjct: 170 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NR+GHS +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP FL+ EA
Sbjct: 230 APEVVNRQGHSHSADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEA 289
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLRALFKRN NRLG+ +G EEIKR FF+ ID+ KL +E+ PPFKPA++ D T
Sbjct: 290 QSLLRALFKRNPTNRLGSAMEGAEEIKRQPFFSTIDWNKLFRREMSPPFKPAVTQADDTY 349
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE--RKLIAKSVRSVPT--AKT 1054
YFD EFT RTPKDSP +P SA H++FRGFSFV+ A++EE +K + V SVP +K
Sbjct: 350 YFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPALVEEDAKKTSSPPVLSVPKTHSKN 409
Query: 1053 NPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQF 874
F D Y + E IG G++SV +C K T +YAVK++ K D +EE++IL R+ H
Sbjct: 410 ILFMDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKTKRDPSEEIEILRRYGQHPN 469
Query: 873 VVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQ 694
++ L DVY++ +IY++ EL GGELLD+++ +K SE+E ++++ + V+ LHSQ
Sbjct: 470 IIALKDVYKEGNSIYVVTELMRGGELLDRILRQKFF-SEREASSVLFTVCKTVENLHSQG 528
Query: 693 VAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQG 514
V HRDL +NIL+ + GDP S+RI DFGFAKQ RA+NG+LMTPCYTA FVAPEVL++QG
Sbjct: 529 VVHRDLKPSNILYVDESGDPESIRICDFGFAKQLRADNGLLMTPCYTANFVAPEVLKRQG 588
Query: 513 YDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKD 334
YD CD+WSLG+LL+TML G TPFA G DTP++IL R+G GK ++ W+T+S AKD
Sbjct: 589 YDEGCDIWSLGILLYTMLAGYTPFANGLGDTPEEILARIGSGKFTLRGGNWNTVSAAAKD 648
Query: 333 LVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKAI 154
LV +ML VDP++R+TAKQ LQH+WI +++ALP Q+ D+ VK A+ TY A+
Sbjct: 649 LVSRMLHVDPHKRLTAKQVLQHEWITKRDALP-----QSQLNRQDVHLVKGAMAATYSAL 703
Query: 153 -ASAPSVQLRPVGSSALAKRRMKEI 82
+S P+ L+P+ SS LA+RR+K++
Sbjct: 704 NSSKPTPLLQPIKSSILAQRRVKKL 728
>gi|47226221|emb|CAG08368.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 719
Score = 812 bits (2097), Expect = 0.0
Identities = 417/699 (59%), Positives = 520/699 (73%), Gaps = 7/699 (1%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D + EI I K G EKADP QFELLKVLGQGSFGKVFLVRK+ G D+G +YAMKVL
Sbjct: 22 DEGTYKEIPITHHVKEGCEKADPSQFELLKVLGQGSFGKVFLVRKILGPDAGQLYAMKVL 81
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKA+LKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKE
Sbjct: 82 KKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKE 141
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGIVYRDLKPENILLD GHIK+TDFGLSKE++D++
Sbjct: 142 VMFTEEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDAD 201
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KK YSFCGTVEYMAPEV+NRRGH+ +AD+WSLGVLMFEMLTG LPFQG+DRN+TM ILK
Sbjct: 202 KKAYSFCGTVEYMAPEVVNRRGHTQSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMILK 261
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+ KL +E+ P
Sbjct: 262 AKLGMPQFLSLEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRRELQP 321
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 1081
PFKPA D T FDPEFT +TPKDSP +P SAN H++F+GFSFV+ A M+E K +
Sbjct: 322 PFKPAAGKPDDTFCFDPEFTAKTPKDSPGIPPSANAHQLFKGFSFVAPAPMDENK-GSPL 380
Query: 1080 VRSVPTAKTN----PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATE 913
+ +P + + F+D YE+ E IG G++S+ +C + + YAVKI+ K D +E
Sbjct: 381 LSILPIVQMHGGSAKFSDLYELQEDIGVGSYSICKRCVHRVSAVDYAVKIIDKIKRDPSE 440
Query: 912 EVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA 733
E++IL+R+ H ++ L DVY++ +Y++ EL +GGELLDK++ +K SE+E +A++
Sbjct: 441 EIEILMRYGQHPNIITLKDVYDEGRYVYLVMELMKGGELLDKILRQKFF-SEREASAVLY 499
Query: 732 NLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYT 553
+ V YLH Q V HRDL +NIL+ G+P S+RI DFGFAKQ R NG+L+TPCYT
Sbjct: 500 TITKTVHYLHCQGVVHRDLKPSNILYMDDSGNPDSIRICDFGFAKQLRGGNGLLLTPCYT 559
Query: 552 AQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMT 373
A FVAPEVL +QGYD +CD+WSLGVLL+TML G TPFA GPNDTP++IL R+G GK S+T
Sbjct: 560 ANFVAPEVLMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLT 619
Query: 372 HPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQ 193
WDT+SD +KDL+ ML VDP++R +A+Q L+H WI ++ LP + L
Sbjct: 620 GGNWDTVSDTSKDLLSHMLHVDPHQRYSAEQVLKHSWITCRDTLPHFQLTRHDAPHL--- 676
Query: 192 NVKVALEQTYKAIASAPSVQ-LRPVGSSALAKRR-MKEI 82
VK A+ TY A++ S L PV +S+LA+RR MK++
Sbjct: 677 -VKGAMAATYSALSQKTSQPVLEPVAASSLAQRRSMKKL 714
>gi|50745818|ref|XP_420257.1| PREDICTED: similar to Ribosomal protein
S6 kinase alpha 6 (S6K-alpha 6) (90 kDa ribosomal protein
S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4)
(pp90RSK4) [Gallus gallus]
Length = 757
Score = 810 bits (2093), Expect = 0.0
Identities = 418/700 (59%), Positives = 514/700 (72%), Gaps = 8/700 (1%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D S EI I K G EKADP QFELLKVLGQGSFGKVFLVRK+ G D+G +YAMKVL
Sbjct: 59 DEGSVKEIPITHHVKEGCEKADPAQFELLKVLGQGSFGKVFLVRKIIGPDAGQLYAMKVL 118
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKA+LKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKE
Sbjct: 119 KKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKE 178
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGIVYRDLKPENILLD GHIK+TDFGLSKE++D E
Sbjct: 179 VMFTEEDVKFYLAELALALDHLHSLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDQE 238
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILK
Sbjct: 239 KKAYSFCGTVEYMAPEVVNRRGHNQSADWWSFGVLMFEMLTGTLPFQGKDRNETMNMILK 298
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ EAQSLLR LFKRN NRLGAG DGVEEIKRH FF+ +D+ KL +EI P
Sbjct: 299 AKLGMPQFLSPEAQSLLRMLFKRNPSNRLGAGSDGVEEIKRHPFFSTVDWNKLFRREIQP 358
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 1081
PFKPA + T FDPEFT +TPKDSP +P SAN H++F+GFSFV+ E+ K I+
Sbjct: 359 PFKPASGKPEDTFCFDPEFTAKTPKDSPGVPPSANAHQLFKGFSFVATTAAEDHK-ISPL 417
Query: 1080 VRSVPTAK-----TNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDAT 916
+P + + FTD YE+ E IG G++SV +C AT ++AVKI+ K+ D +
Sbjct: 418 TNILPIVQQLHGNSAQFTDVYELKEDIGVGSYSVCKRCIHIATNMEFAVKIIDKSKRDPS 477
Query: 915 EEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIM 736
EE++IL+R+ H ++ L DVY+D IY++ EL +GGELLD+++ +K SE+E +A++
Sbjct: 478 EEIEILMRYGQHPNIITLKDVYDDGRFIYLVTELMKGGELLDRILRQKFF-SEREASAVL 536
Query: 735 ANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCY 556
+ V YLH Q V HRDL +NIL+ + S+RI DFGFAKQ R ENG+L+TPCY
Sbjct: 537 YTITKTVDYLHCQGVVHRDLKPSNILYTDDSNNADSIRICDFGFAKQLRGENGLLLTPCY 596
Query: 555 TAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISM 376
TA FVAPEVL +QGYD +CD+WSLGVLL+TML G TPFA GPNDTP++IL R+G GK S+
Sbjct: 597 TANFVAPEVLMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILVRIGSGKFSL 656
Query: 375 THPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDM 196
+ WDT+SD AKDL+ ML VDP++R TA+Q L+H WI ++ LP + + L
Sbjct: 657 SGGNWDTVSDAAKDLLSHMLHVDPHQRYTAEQVLKHSWIACRDQLPHYQLNRQDAPHL-- 714
Query: 195 QNVKVALEQTYKAIASAP-SVQLRPVGSSALAKRR-MKEI 82
VK A+ TY A+ L PV +S+LA+RR MK++
Sbjct: 715 --VKGAMAATYSALNHKTFQPVLEPVAASSLAQRRSMKKL 752
>gi|47230027|emb|CAG10441.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 732
Score = 809 bits (2089), Expect = 0.0
Identities = 416/722 (57%), Positives = 525/722 (72%), Gaps = 36/722 (4%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EI+I V K G EKAD QFELLKVLGQGSFGKVFLVRKV D+ +YAMKVLKKATLK
Sbjct: 8 EINITHVVKEGSEKADASQFELLKVLGQGSFGKVFLVRKVTPPDANQLYAMKVLKKATLK 67
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR RTK+ERNILA ++HPF+VKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 68 VRDRVRTKMERNILADVNHPFVVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 127
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGL KEAID EKK YSF
Sbjct: 128 DVKFYLAELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLCKEAIDHEKKAYSF 187
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGTVEYMAPEV+NR+GH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKA+L MP
Sbjct: 188 CGTVEYMAPEVVNRQGHTHSADWWSFGVLMFEMLTGALPFQGKDRKETMNLILKARLGMP 247
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLG+G DG EEIKRH FF+ ID+ KL +E+ PPF+PA+
Sbjct: 248 QFLSAEAQSLLRALFKRNPANRLGSGADGAEEIKRHGFFSTIDWNKLFRREMKPPFRPAV 307
Query: 1242 STVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERK----------- 1096
+ D T YFD EFT RTPKDSP +P SA H++FRGFSF+++ ++EE
Sbjct: 308 ARPDDTFYFDSEFTSRTPKDSPGVPPSAGAHQLFRGFSFIASTLLEEEGSEEQVKPQPHP 367
Query: 1095 ---------LIAKSVRSVPTAKTNP---------FTDDYEILEKIGNGAHSVVHKCQMKA 970
+ + + + T + +P F+D Y + E IG G+ SV +C KA
Sbjct: 368 VVQVGPWVWVGSPAAAAAATTRLSPQQLHGKNLLFSDGYVLKEDIGMGSFSVCKRCIHKA 427
Query: 969 TRRKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLD 790
T +YAVK++ K D +EE++ILLR+ H ++ L DVY++ ++++ EL GGELLD
Sbjct: 428 TNTEYAVKMIDKTSTDPSEEIEILLRYGQHPNIITLKDVYDNGKQVFLVTELMRGGELLD 487
Query: 789 KLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDF 610
+++ +K SE+E +A++ + V+YLHSQ V HRDL +NIL+ G+P S+RI DF
Sbjct: 488 RILKQKFF-SEREASAVLHTITRTVEYLHSQGVVHRDLKPSNILYVDDSGNPESIRICDF 546
Query: 609 GFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGP 430
GFAKQ RA NG+LMTPCYTA FVAPEVL++QGYD CD+WSLGVLL+TML G TPFA GP
Sbjct: 547 GFAKQLRANNGLLMTPCYTANFVAPEVLKRQGYDEGCDIWSLGVLLYTMLAGFTPFANGP 606
Query: 429 NDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQK 250
DTPD+IL R+G+G S+ WDT+SD AKDLV KML VDP++R+TA+Q L+H WI +
Sbjct: 607 EDTPDEILNRIGNGHFSLGGGNWDTVSDAAKDLVSKMLHVDPHQRLTARQVLRHPWIVHR 666
Query: 249 EALPDRPIQSE-----QVGELDMQNVKVALEQTYKAIA-SAPSVQLRPVGSSALAKRRMK 88
+ LP+ + +V +LD + + A+ TY A+ S P+ +L+P+ SS LA+RR++
Sbjct: 667 DKLPNSQLPHHDPKLVKVIQLD-EPIGGAMAATYSALKNSQPTPELKPIESSFLAQRRVR 725
Query: 87 EI 82
++
Sbjct: 726 KL 727
>gi|41056055|ref|NP_956367.1| Unknown (protein for MGC:66139);
wu:fj94b02 [Danio rerio]
gi|34785761|gb|AAH57467.1| Unknown (protein for MGC:66139) [Danio
rerio]
Length = 740
Score = 809 bits (2089), Expect = 0.0
Identities = 414/699 (59%), Positives = 516/699 (73%), Gaps = 7/699 (1%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D + EI I K G EKADP QFELLKVLGQGSFGKVFLVRK+ G D+G +YAMKVL
Sbjct: 42 DEGAYKEIPITHHVKEGCEKADPSQFELLKVLGQGSFGKVFLVRKLMGPDAGQLYAMKVL 101
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKA+LKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKE
Sbjct: 102 KKASLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKE 161
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGIVYRDLKPENILLD GHIK+TDFGLSKE++D +
Sbjct: 162 VMFTEEDVKFYLAELALALDHLHNLGIVYRDLKPENILLDEAGHIKLTDFGLSKESVDQD 221
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KK YSFCGTVEYMAPEV+NRRGH+ +AD+WSLGVLMFEMLTG LPFQG+DRN+TM ILK
Sbjct: 222 KKAYSFCGTVEYMAPEVVNRRGHTQSADWWSLGVLMFEMLTGTLPFQGKDRNETMNMILK 281
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ EAQ LLR LFKRN NRLGAGPDGVEEIKRH FF+ ID+ KL +E+ P
Sbjct: 282 AKLGMPQFLSLEAQGLLRMLFKRNPSNRLGAGPDGVEEIKRHTFFSTIDWNKLYRRELQP 341
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 1081
PFKPA D T FDPEFT +TPKDSP +P SAN H++F+GFSFV+ +EE K A
Sbjct: 342 PFKPASGKPDDTFCFDPEFTAKTPKDSPGIPPSANAHQLFKGFSFVAPVSLEESK-SAPL 400
Query: 1080 VRSVPTAKTN----PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATE 913
V +P + + F+D YE+ E IG G++S+ +C + T ++AVKI+ K+ D +E
Sbjct: 401 VNILPIVQVHGSSAQFSDVYELKEDIGVGSYSICKRCIHRVTAMEFAVKIIDKSKRDPSE 460
Query: 912 EVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMA 733
E++IL+R+ H ++ L DVY++ +Y++ EL +GGELLDK++ +K SE+E +A++
Sbjct: 461 EIEILMRYGQHPNIITLKDVYDEGRFVYLVTELMKGGELLDKILRQKFF-SEREASAVLY 519
Query: 732 NLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYT 553
+ V YLH Q V HRDL +NIL+ G+P S+RI DFGFAKQ R +NG+L+TPCYT
Sbjct: 520 TITKTVDYLHCQGVVHRDLKPSNILYMDDSGNPDSIRICDFGFAKQLRGDNGLLLTPCYT 579
Query: 552 AQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMT 373
A FVAPEVL +QGYD +CD+WSLGVLL+TML G TPFA GPNDTP++IL R+G GK S++
Sbjct: 580 ANFVAPEVLMRQGYDAACDIWSLGVLLYTMLAGYTPFANGPNDTPEEILLRIGSGKFSLS 639
Query: 372 HPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQ 193
WD++SD +KDL+ ML VDP+ R TA+Q L+H WI ++ P + + L
Sbjct: 640 GGNWDSVSDSSKDLLSHMLHVDPHHRYTAEQVLKHSWIACRDQNPHFQLTRHEAPHL--- 696
Query: 192 NVKVALEQTYKAI-ASAPSVQLRPVGSSALAKRR-MKEI 82
VK A+ TY A+ L PV +S+LA+RR MK++
Sbjct: 697 -VKGAMAATYSALNHKTCKPVLEPVAASSLAQRRNMKKL 734
>gi|19310195|dbj|BAB85907.1| p90 ribosomal S6 kinase [Asterina
pectinifera]
Length = 738
Score = 808 bits (2088), Expect = 0.0
Identities = 423/710 (59%), Positives = 519/710 (72%), Gaps = 18/710 (2%)
Frame = -1
Query: 2169 EEKTDSSSETE------IDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRD 2011
E DS++ETE I+I + G +K+DP QFELLKVLGQGSFGKVFLVRKV G D
Sbjct: 26 EMLVDSTNETEDQEMREINITSMAAEGLQKSDPSQFELLKVLGQGSFGKVFLVRKVFGED 85
Query: 2010 SGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRG 1831
SG +YAMKVLKKATLKVRDR RTK+ERNIL ++HPFIVKLHYAFQTEGKLYLILDFLRG
Sbjct: 86 SGTLYAMKVLKKATLKVRDRMRTKMERNILVDVNHPFIVKLHYAFQTEGKLYLILDFLRG 145
Query: 1830 GDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDF 1651
GDLFTRLSKEVMFTEDD K Y LGI+YRDLKPENILLDA GHIK+TDF
Sbjct: 146 GDLFTRLSKEVMFTEDDAKLYPAELALALDHLHSLGIIYRDLKPENILLDASGHIKLTDF 205
Query: 1650 GLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRD 1471
GLSKE++D+ K TYSFCGTVEYMAPEV+NRRGH+ AAD+WS GVLMFEMLTG LPFQG+
Sbjct: 206 GLSKESVDNSK-TYSFCGTVEYMAPEVVNRRGHTTAADWWSFGVLMFEMLTGALPFQGQH 264
Query: 1470 RNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDF 1291
R +TM I KAKL MP FL+ EAQSLLR LFKRN NRLGA +GVE+IK+HAFFA IDF
Sbjct: 265 RKETMAMIPKAKLGMPQFLSPEAQSLLRQLFKRNPANRLGAAENGVEDIKKHAFFAHIDF 324
Query: 1290 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV 1111
KLL KEI PPFKPA+S D T YFD EFT RTPKDSP LP SA+ H++FRGFS+++ +
Sbjct: 325 EKLLRKEISPPFKPAVSNADDTFYFDTEFTSRTPKDSPGLPPSASAHQLFRGFSYIAPVL 384
Query: 1110 MEERKL----------IAKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRR 961
++E ++ AK V A+ ++YE+ + IG G+ S +C K++ +
Sbjct: 385 LQEDEMKAATNNTHTQPAKETLPVKHARVTSIAEEYELQDVIGLGSFSKCLRCLHKSSGQ 444
Query: 960 KYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLV 781
+YAVKI+KK + EE++++LR+ HH ++ L DVY+D +YM+ EL +GGELLDK++
Sbjct: 445 QYAVKIIKKGKKEVQEEIEVMLRYGHHPNIITLRDVYDDGQNVYMVMELMKGGELLDKIL 504
Query: 780 NKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFA 601
KK L SE+E IM + V YLH Q+V HRDL +NIL+A G+PSSLRI DFGFA
Sbjct: 505 KKKCL-SEREACEIMHVVTKTVDYLHQQRVVHRDLKPSNILYADDSGNPSSLRISDFGFA 563
Query: 600 KQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDT 421
KQ RA+NGMLMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+TML G TPFA GP D+
Sbjct: 564 KQMRADNGMLMTPCYTANFVAPEVLKRQGYDAACDIWSLGVLLYTMLAGYTPFAHGPEDS 623
Query: 420 PDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEAL 241
+ IL R+G+GK + WD +S A++LVR ML VDP +R +A + LQH W+ E+L
Sbjct: 624 AEIILARIGEGKFPLNGGNWDHVSPMAEELVRWMLHVDPFKRPSAAKVLQHPWMQHCESL 683
Query: 240 PDRPIQSEQVGELDMQNVKVALEQTYKAIASAPSVQ-LRPVGSSALAKRR 94
+ ++ D VK A++ TY A+ + P V+ L PV SS LA+RR
Sbjct: 684 SQNRLTTQ-----DYDLVKGAMKATYLALNNQPKVENLEPVTSSMLAQRR 728
>gi|7657526|ref|NP_055311.1| ribosomal protein S6 kinase, 90kDa,
polypeptide 6; ribosomal protein S6 kinase, 90kD,
polypeptide 6 [Homo sapiens]
gi|11133131|sp|Q9UK32|K6A6_HUMAN Ribosomal protein S6 kinase alpha 6
(S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6)
(p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)
gi|6467562|gb|AAF13190.1| ribosomal S6 kinase [Homo sapiens]
Length = 745
Score = 791 bits (2043), Expect = 0.0
Identities = 405/682 (59%), Positives = 504/682 (73%), Gaps = 6/682 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QFELLKVLGQGSFGKVFLVRK G D+G +YAMKVLKKA+LKVRDR RT
Sbjct: 61 VKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRT 120
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKEV+FTE+DVKFY
Sbjct: 121 KMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 180
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 181 ELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 240
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRRGHS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP FL+ EA
Sbjct: 241 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 300
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEEIKRH FFA ID+ KL +E+ PPFKPA D T
Sbjct: 301 QSLLRMLFKRNPANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTF 358
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPKDSP LPASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 359 CFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGN 418
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F + YE+ E IG G++SV +C T ++AVKI+ K+ D +EE++IL+R+ H
Sbjct: 419 AAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHP 478
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L DV++D +Y++ +L +GGELLD+++ +K SE+E + I+ + V YLH Q
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCF-SEREASDILYVISKTVDYLHCQ 537
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + S+RI DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQ 597
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVL +TML G TPFA GPNDTP++IL R+G+GK S++ WD ISD AK
Sbjct: 598 GYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAK 657
Query: 336 DLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKA 157
DL+ ML +DP++R TA+Q L+H WI ++ LP+ + V + VK A+ TY A
Sbjct: 658 DLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHV----VKGAMVATYSA 713
Query: 156 IASAP-SVQLRPVGSSALAKRR 94
+ L PV +S+LA+RR
Sbjct: 714 LTHKTFQPVLEPVAASSLAQRR 735
>gi|33303997|gb|AAQ02506.1| ribosomal protein S6 kinase, 90kDa,
polypeptide 6 [synthetic construct]
Length = 746
Score = 791 bits (2043), Expect = 0.0
Identities = 405/682 (59%), Positives = 504/682 (73%), Gaps = 6/682 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QFELLKVLGQGSFGKVFLVRK G D+G +YAMKVLKKA+LKVRDR RT
Sbjct: 61 VKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRT 120
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKEV+FTE+DVKFY
Sbjct: 121 KMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 180
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 181 ELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 240
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRRGHS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP FL+ EA
Sbjct: 241 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 300
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEEIKRH FFA ID+ KL +E+ PPFKPA D T
Sbjct: 301 QSLLRMLFKRNPANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTF 358
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPKDSP LPASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 359 CFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGN 418
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F + YE+ E IG G++SV +C T ++AVKI+ K+ D +EE++IL+R+ H
Sbjct: 419 AAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHP 478
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L DV++D +Y++ +L +GGELLD+++ +K SE+E + I+ + V YLH Q
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCF-SEREASDILYVISKTVDYLHCQ 537
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + S+RI DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQ 597
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVL +TML G TPFA GPNDTP++IL R+G+GK S++ WD ISD AK
Sbjct: 598 GYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAK 657
Query: 336 DLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKA 157
DL+ ML +DP++R TA+Q L+H WI ++ LP+ + V + VK A+ TY A
Sbjct: 658 DLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHV----VKGAMVATYSA 713
Query: 156 IASAP-SVQLRPVGSSALAKRR 94
+ L PV +S+LA+RR
Sbjct: 714 LTHKTFQPVLEPVAASSLAQRR 735
>gi|49168616|emb|CAG38803.1| RPS6KA6 [Homo sapiens]
Length = 745
Score = 785 bits (2026), Expect = 0.0
Identities = 403/682 (59%), Positives = 501/682 (73%), Gaps = 6/682 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QFELLKVLGQGSFGKVFLVRK G D+G +YAMKVLKKA+LKVR R RT
Sbjct: 61 VKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRGRVRT 120
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKEV+FTE+DVKFY
Sbjct: 121 KMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 180
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 181 ELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 240
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRRGHS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP L+ EA
Sbjct: 241 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQLLSAEA 300
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEEIKRH FFA ID+ KL E+ PPFKPA D T
Sbjct: 301 QSLLRMLFKRNPANRLGS--EGVEEIKRHLFFANIDWDKLYKGEVQPPFKPASGKPDDTF 358
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPKDSP LPASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 359 CFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGN 418
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F + YE+ E IG G++SV +C T ++AVKI+ K+ D +EE++IL+R+ H
Sbjct: 419 AAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHP 478
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L DV++D +Y++ +L +GGELLD+++ +K SE+E + I+ + V YLH Q
Sbjct: 479 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCF-SEREASDILYVISKTVDYLHCQ 537
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + S+RI DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 538 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQ 597
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVL +TML G TPFA GPNDTP++IL R+G+GK S++ WD ISD AK
Sbjct: 598 GYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAK 657
Query: 336 DLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQTYKA 157
DL+ ML +DP++R TA+Q L+H WI ++ LP+ + V + VK A+ TY A
Sbjct: 658 DLLSHMLHMDPHQRYTAEQILKHSWITHRDQLPNDQPKRNDVSHV----VKGAMVATYSA 713
Query: 156 IASAP-SVQLRPVGSSALAKRR 94
+ L PV +S+LA+RR
Sbjct: 714 LTHKTFQPVLEPVAASSLAQRR 735
>gi|31205767|ref|XP_311835.1| ENSANGP00000018211 [Anopheles gambiae]
gi|21295747|gb|EAA07892.1| ENSANGP00000018211 [Anopheles gambiae str.
PEST]
Length = 863
Score = 785 bits (2026), Expect = 0.0
Identities = 402/724 (55%), Positives = 516/724 (70%), Gaps = 32/724 (4%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
+ E EIDI D+ + G EKADP QFELLKVLG+GSFGKVFLVRK+ G D+G +YAMKVL
Sbjct: 140 NGGDEHEIDIKDIIREGHEKADPSQFELLKVLGEGSFGKVFLVRKIVGIDAGTLYAMKVL 199
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKATLKV+DR R+ ERNILA + H FIVKLHYAFQT GKLYLILDFLRGGDLFTRLSKE
Sbjct: 200 KKATLKVKDRVRSTNERNILADVGHAFIVKLHYAFQTPGKLYLILDFLRGGDLFTRLSKE 259
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY +GI+YRDLKPENILLD DGHI +TDFGLSK+ +D
Sbjct: 260 VMFTEEDVKFYLAELALALNHLHSIGIIYRDLKPENILLDQDGHIALTDFGLSKQPLDG- 318
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
KTYSFCGTVEYMAPEV+NR+GH+ AAD+WS GVLMFEMLTG+LPF G +RNDTM QILK
Sbjct: 319 SKTYSFCGTVEYMAPEVVNRKGHTFAADWWSFGVLMFEMLTGNLPFHGSNRNDTMNQILK 378
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
KL MP L+ EAQSLLRALFKRN QNRLGAGP+G+E+IKRH FFA +D+ KE+ P
Sbjct: 379 TKLGMPENLSPEAQSLLRALFKRNPQNRLGAGPNGIEDIKRHEFFANVDWDAFERKEVRP 438
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLIAKS 1081
PF PA+S D YFD E+T ++PKDSP P SA+ HEIFRGFSF++ +++E+ A
Sbjct: 439 PFIPAVSR-DDAFYFDSEYTNKSPKDSPGGPVSASAHEIFRGFSFIAPGLLDEQPNFANG 497
Query: 1080 ---------------VRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVK 946
+P K F D+Y ++E++G G S+ C+ + T++ YAVK
Sbjct: 498 SNMVMQQQPASRSPFSNEIPGVKPVAFGDEYNLMEELGRGTFSICRMCEHRTTKKHYAVK 557
Query: 945 IVKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSL 766
I+ K+ D EEV+ILLR+ +H +V L+ V+ED + +Y++ EL +GGELLD+++ +
Sbjct: 558 IIDKSYHDCREEVEILLRYGNHPNIVTLYGVHEDASYVYLVMELLKGGELLDRILAIHFM 617
Query: 765 GSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRA 586
+E+E +A++ +++AV YLH V HRDL +N+L+A + P SL++ D GFAKQ RA
Sbjct: 618 -AEQEASAVLRTVVSAVAYLHEHGVVHRDLKPSNLLYASVNHTPESLKLCDLGFAKQLRA 676
Query: 585 ENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQIL 406
+NG+LMTPCYTA FVAPEVL+KQGYD +CD+WSLGVLL+ ML G TPFA PND+PD IL
Sbjct: 677 DNGLLMTPCYTANFVAPEVLKKQGYDLACDIWSLGVLLYIMLDGKTPFASTPNDSPDMIL 736
Query: 405 QRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKW------------ 262
R+G GK+ + W TISDE KDL+R+ML + P+RR TA Q L+H W
Sbjct: 737 ARIGSGKVDLETGKWPTISDEVKDLLRQMLHIVPSRRPTAAQILRHPWLSRSGPRLMYNT 796
Query: 261 IGQKEALPDRPI----QSEQVGELDMQNVKVALEQTYKAIASAPSVQLRPVGSSALAKRR 94
+G + A +RP+ Q + ++ + +K A+ T++AI+S + L PVG S LA+RR
Sbjct: 797 VGTQHATSERPMVVEPQDTKPACVNTEAIKGAVHATFRAISSPQAANLGPVGMSDLARRR 856
Query: 93 MKEI 82
M ++
Sbjct: 857 MDKM 860
>gi|29789163|ref|NP_080225.1| ribosomal protein S6 kinase polypeptide
6 [Mus musculus]
gi|26340070|dbj|BAC33698.1| unnamed protein product [Mus musculus]
Length = 766
Score = 777 bits (2007), Expect = 0.0
Identities = 386/633 (60%), Positives = 487/633 (75%), Gaps = 5/633 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QF+LLKVLGQGSFGKVFLVRK G D+G +YAMKVL+KA+LKVRDR RT
Sbjct: 98 VKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRT 157
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHYAFQ+EGKLYLILDFLRGGD+FTRLSKEV+FTE+DVKFY
Sbjct: 158 KMERDILVEVNHPFIVKLHYAFQSEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 217
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 218 ELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 277
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRRGHS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP FL+ EA
Sbjct: 278 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 337
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEE+KRHAFFA ID+ KL +E+ PPF+PA D T
Sbjct: 338 QSLLRMLFKRNPANRLGS--EGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTF 395
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPKDSP LPASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 396 CFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGN 455
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F++ YE+ E IG G++SV +C A+ ++AVKI+ K D +EE++IL+R+ H
Sbjct: 456 AAQFSEAYELKEDIGIGSYSVCKRCIHSASNVEFAVKIIDKNKRDPSEEIEILMRYGQHP 515
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L +V++D +Y++ +L +GGELLD+++ KK SE+E + ++ + V+ LHSQ
Sbjct: 516 NIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCF-SEQEASNVLYVITKTVECLHSQ 574
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + P S++I DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 575 GVVHRDLKPSNILYMDESAHPDSIKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQQ 634
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVLL+TML G TPF+ GPNDTP++IL RVG+G+ S++ +WD IS AK
Sbjct: 635 GYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRVGNGRFSLSGGIWDNISRGAK 694
Query: 336 DLVRKMLDVDPNRRVTAKQALQHKWIGQKEALP 238
DL+ ML +DP++R TA+Q L+H WI Q+E LP
Sbjct: 695 DLLSHMLHMDPHQRYTAEQVLKHPWITQREQLP 727
>gi|91277|pir||C32571 ribosomal protein S6 kinase II (EC 2.7.-.-)
alpha chain homolog (clone Mu7A) - mouse (fragment)
Length = 633
Score = 760 bits (1963), Expect = 0.0
Identities = 381/628 (60%), Positives = 470/628 (74%), Gaps = 4/628 (0%)
Frame = -1
Query: 1965 KVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE 1786
KVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE
Sbjct: 1 KVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE 60
Query: 1785 DDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYS 1606
+DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKE+ID EKK YS
Sbjct: 61 EDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKESIDHEKKAYS 120
Query: 1605 FCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSM 1426
FCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL M
Sbjct: 121 FCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILKAKLGM 180
Query: 1425 PHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPA 1246
P FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+ KL +EI PPFKPA
Sbjct: 181 PQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDWNKLYRREIHPPFKPA 240
Query: 1245 LSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI----AKSV 1078
+ T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+ +E + + S+
Sbjct: 241 TGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSI 300
Query: 1077 RSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDIL 898
+ FTD YE+ E IG G++SV +C KAT ++AVKI+ K+ D TEE++IL
Sbjct: 301 VQQLHRNSIQFTDGYEVKEDIGVGSYSVCKRCIHKATNMEFAVKIIDKSKRDPTEEIEIL 360
Query: 897 LRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNA 718
LR+ H ++ L DVY+D +Y++ EL +GGELLDK++ +K SE+E +A++ +
Sbjct: 361 LRYGQHPNIITLKDVYDDGKYVYVVTELMKGGELLDKILRQKFF-SEREASAVLFTITKT 419
Query: 717 VQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVA 538
V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAENG+LMTPCYTA FVA
Sbjct: 420 VEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVA 479
Query: 537 PEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWD 358
PEVL++QGYD +CD+WSLGVLL+TMLTG TPFA GP+DTP++IL R+G GK S++ W+
Sbjct: 480 PEVLKRQGYDAACDIWSLGVLLYTMLTGYTPFANGPDDTPEEILARIGSGKFSLSGGYWN 539
Query: 357 TISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVA 178
++SD AKDLV KML VDP++R+TA L+H WI + LP + + L VK A
Sbjct: 540 SVSDTAKDLVSKMLHVDPHQRLTAALVLRHPWIVHWDQLPQYQLNRQDAPHL----VKGA 595
Query: 177 LEQTYKAIASAPSVQLRPVGSSALAKRR 94
+ TY A+ S L PVG S LA+RR
Sbjct: 596 MAATYSALNRNQSPVLEPVGRSTLAQRR 623
>gi|34853790|ref|XP_341759.1| ribosomal protein S6 kinase, 90kD,
polypeptide 2 [Rattus norvegicus]
Length = 833
Score = 756 bits (1952), Expect = 0.0
Identities = 390/649 (60%), Positives = 473/649 (72%), Gaps = 48/649 (7%)
Frame = -1
Query: 2139 EIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLK 1963
EIDI K G EKADP QFELLKVLGQGS+GKVFLVRKV G D+G +YAMKVLKKATLK
Sbjct: 29 EIDISSHVKEGFEKADPSQFELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLK 88
Query: 1962 VRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTED 1783
VRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+
Sbjct: 89 VRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEE 148
Query: 1782 DVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSF 1603
DVKFY LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID +K+ YSF
Sbjct: 149 DVKFYLAELALALDHLHGLGIIYRDLKPENILLDEEGHIKITDFGLSKEAIDHDKRAYSF 208
Query: 1602 CGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMP 1423
CGT+EYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+DR +TM ILKAKL MP
Sbjct: 209 CGTIEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILKAKLGMP 268
Query: 1422 HFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPAL 1243
FL+ EAQSLLRALFKRN NRLGAG DGVEEIKRH FF ID+ KL KEI PPFKPA+
Sbjct: 269 QFLSAEAQSLLRALFKRNPCNRLGAGVDGVEEIKRHPFFVTIDWNKLYRKEIKPPFKPAV 328
Query: 1242 STVDSTSYFDPEFTKRTP------------------------------------KDSPAL 1171
+ T +FDPEFT RTP +SP +
Sbjct: 329 GRPEDTFHFDPEFTARTPTGKTKTVVSSKTEVGVSMKIVMLHVTDATVWSAHDSMNSPGV 388
Query: 1170 PASANGHEIFRGFSFVSNAVMEERKLIAKSVRSVPTAKTNP-----------FTDDYEIL 1024
P SAN H +FRGFSFV++++++E S + VP A +P FTD YEI
Sbjct: 389 PPSANAHHLFRGFSFVASSLVQE-----PSQQDVPKAPIHPIVQQLHGNNIHFTDGYEIK 443
Query: 1023 EKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQFVVKLFDVYED 844
E IG G++SV +C KAT +YAVKI+ K+ D +EE++ILLR+ H ++ L DVY+D
Sbjct: 444 EDIGVGSYSVCKRCVHKATDAEYAVKIIDKSKRDPSEEIEILLRYGQHPNIITLKDVYDD 503
Query: 843 ETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAAN 664
+Y++ EL GGELLD+++ ++ SE+E + ++ + + YLHSQ V HRDL +N
Sbjct: 504 GKYVYLVMELMRGGELLDRILRQRCF-SEREASDVLYTIARTMDYLHSQGVVHRDLKPSN 562
Query: 663 ILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSL 484
IL+ + G+P S+RI DFGFAKQ RAENG+LMTPCYTA FVAPEVL++QGYD +CDVWSL
Sbjct: 563 ILYMDESGNPESIRICDFGFAKQLRAENGLLMTPCYTANFVAPEVLKRQGYDAACDVWSL 622
Query: 483 GVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
G+LL+TML G TPFA GP+DTP++IL R+G GK +++ WD+ISD AK
Sbjct: 623 GILLYTMLAGFTPFANGPDDTPEEILARIGSGKYALSGGNWDSISDAAK 671
Score = 115 bits (287), Expect = 6e-24
Identities = 78/259 (30%), Positives = 137/259 (52%), Gaps = 9/259 (3%)
Frame = -1
Query: 1035 YEILEKIGNGAHS---VVHKCQMKATRRKYAVKIVKKAVFDATEEVDI-----LLRHSHH 880
+E+L+ +G G++ +V K + YA+K++KKA + V +L +H
Sbjct: 48 FELLKVLGQGSYGKVFLVRKVTGSDAGQLYAMKVLKKATLKVRDRVRSKMERDILAEVNH 107
Query: 879 QFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHS 700
F+VKL ++ E +Y+I + GG+L +L +K+ + +E++V +A L A+ +LH
Sbjct: 108 PFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL-SKEVMFTEEDVKFYLAELALALDHLHG 166
Query: 699 QQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRK 520
+ +RDL NIL + ++I DFG +K++ + + C T +++APEV+ +
Sbjct: 167 LGIIYRDLKPENILL----DEEGHIKITDFGLSKEAIDHDKRAYSFCGTIEYMAPEVVNR 222
Query: 519 QGYDRSCDVWSLGVLLHTMLTGCTPF-AMGPNDTPDQILQRVGDGKISMTHPVWDTISDE 343
+G+ +S D WS GVL+ MLTG PF +T IL+ K+ M +S E
Sbjct: 223 RGHTQSADWWSFGVLMFEMLTGSLPFQGKDRKETMALILK----AKLGMP----QFLSAE 274
Query: 342 AKDLVRKMLDVDPNRRVTA 286
A+ L+R + +P R+ A
Sbjct: 275 AQSLLRALFKRNPCNRLGA 293
Score = 61.2 bits (147), Expect = 1e-07
Identities = 37/85 (43%), Positives = 50/85 (58%), Gaps = 1/85 (1%)
Frame = -1
Query: 345 EAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQVGELDMQNVKVALEQT 166
E +D+V KML VDP +R+TA Q L+H WI +E L Q+ D+ VK A+ T
Sbjct: 744 EQRDVVSKMLHVDPQQRLTAVQVLKHPWIVNREYL-----SQNQLSRQDVHLVKGAMAAT 798
Query: 165 YKAIASAPSV-QLRPVGSSALAKRR 94
Y A+ P +L PV SS+LA+RR
Sbjct: 799 YFALNRTPQAPRLEPVLSSSLAQRR 823
>gi|11181910|emb|CAC16111.1| bA54F22.1.1 (ribosomal protein S6 kinase,
90kD, polypeptide 6) [Homo sapiens]
Length = 656
Score = 743 bits (1919), Expect = 0.0
Identities = 374/600 (62%), Positives = 457/600 (75%), Gaps = 5/600 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QFELLKVLGQGSFGKVFLVRK G D+G +YAMKVLKKA+LKVRDR RT
Sbjct: 60 VKEGYEKADPAQFELLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLKKASLKVRDRVRT 119
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKEV+FTE+DVKFY
Sbjct: 120 KMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 179
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 180 ELALALDHLHQLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 239
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRRGHS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP FL+ EA
Sbjct: 240 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 299
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEEIKRH FFA ID+ KL +E+ PPFKPA D T
Sbjct: 300 QSLLRMLFKRNPANRLGS--EGVEEIKRHLFFANIDWDKLYKREVQPPFKPASGKPDDTF 357
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPKDSP LPASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 358 CFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGN 417
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F + YE+ E IG G++SV +C T ++AVKI+ K+ D +EE++IL+R+ H
Sbjct: 418 AAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSKRDPSEEIEILMRYGQHP 477
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L DV++D +Y++ +L +GGELLD+++ +K SE+E + I+ + V YLH Q
Sbjct: 478 NIITLKDVFDDGRYVYLVTDLMKGGELLDRILKQKCF-SEREASDILYVISKTVDYLHCQ 536
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + S+RI DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 537 GVVHRDLKPSNILYMDESASADSIRICDFGFAKQLRGENGLLLTPCYTANFVAPEVLMQQ 596
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVL +TML G TPFA GPNDTP++IL R+G+GK S++ WD ISD AK
Sbjct: 597 GYDAACDIWSLGVLFYTMLAGYTPFANGPNDTPEEILLRIGNGKFSLSGGNWDNISDGAK 656
>gi|32450549|gb|AAH54113.1| Rps6ka6 protein [Mus musculus]
Length = 720
Score = 742 bits (1916), Expect = 0.0
Identities = 376/633 (59%), Positives = 475/633 (74%), Gaps = 14/633 (2%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QF+LLKVLGQGSFGKVFLVRK G D+G +YAMKVL+KA+LKVRDR RT
Sbjct: 81 VKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRT 140
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRGGD+FTRLSKEV+FTE+DVKFY
Sbjct: 141 KMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDVFTRLSKEVLFTEEDVKFYLA 200
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 201 ELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 260
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRR HS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP FL+ EA
Sbjct: 261 APEVVNRRAHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 320
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEE+KRHAFFA ID+ KL +E+ PPF+PA D T
Sbjct: 321 QSLLRMLFKRNPANRLGS--EGVEEVKRHAFFASIDWNKLYKREVQPPFRPASGKPDDTF 378
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPKDSP LPASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 379 CFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGN 438
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F++ YE+ E IG G++SV +C A+ ++AVKI+ K D +EE++IL+R+ H
Sbjct: 439 AAQFSEAYELKEDIGIGSYSVCKRCIHSASNVEFAVKIIDKNKRDPSEEIEILMRYGQHP 498
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L +V++D +Y++ +L +GGELLD+++ KK SE+E + ++ + V+ LHSQ
Sbjct: 499 NIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCF-SEQEASNVLYVITKTVECLHSQ 557
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + P S++I DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 558 GVVHRDLKPSNILYMDESAHPDSIKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQQ 617
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVLL+TML G TPF+ GPNDTP++IL R+G+G+ S++ +WD IS AK
Sbjct: 618 GYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAK 677
Query: 336 DLVR---KMLDVDPNRR------VTAKQALQHK 265
+ V +L +PNR VTA + Q +
Sbjct: 678 EAVAAPYSVLARNPNRHHPILEPVTASRLAQRR 710
>gi|125694|sp|P10666|K6AB_XENLA Ribosomal protein S6 kinase II beta
(S6KII-beta) (P90-RSK)
gi|85848|pir||A30001 ribosomal protein S6 kinase (EC 2.7.-.-) II beta
chain - African clawed frog
gi|214789|gb|AAA49959.1| S6 kinase II beta
Length = 629
Score = 742 bits (1916), Expect = 0.0
Identities = 368/580 (63%), Positives = 450/580 (77%), Gaps = 4/580 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKAD F LLKVLGQGSFGKVFLVRK+ D+ +YAMKVLKKATLKVRDR RT
Sbjct: 50 VKEGAEKADQSHFVLLKVLGQGSFGKVFLVRKITPPDANQLYAMKVLKKATLKVRDRVRT 109
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+ILA + HPF+V+LHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTE+DVKFY
Sbjct: 110 KMERDILADVHHPFVVRLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEEDVKFYLA 169
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGI+YRDLKPENILLD +GHIK+TDFGLSKEAID EKK YSFCGTVEYM
Sbjct: 170 ELALGLDHLHSLGIIYRDLKPENILLDEEGHIKLTDFGLSKEAIDHEKKAYSFCGTVEYM 229
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NR+GHS AD+WS GVLMFEMLTG LPFQG+DR +TMT ILKAKL MP FL+ EA
Sbjct: 230 APEVVNRQGHSHGADWWSYGVLMFEMLTGSLPFQGKDRKETMTLILKAKLGMPQFLSNEA 289
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLRALFKRN+ NRLG+G +G EE+KRH FF+ ID+ KL +E+ PPFKP+++ D T
Sbjct: 290 QSLLRALFKRNATNRLGSGVEGAEELKRHPFFSTIDWNKLYRRELSPPFKPSVTQPDDTY 349
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEE--RKLIAKSVRSVPT--AKT 1054
YFD EFT RTPKDSP +P SA H++FRGFSFV+ ++EE +K + V SVP +K
Sbjct: 350 YFDTEFTSRTPKDSPGIPPSAGAHQLFRGFSFVAPVLVEEDAKKTSSPPVLSVPKTHSKN 409
Query: 1053 NPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQF 874
FTD Y + E IG G++SV +C K T +YAVK++ K+ D +EE++IL R+ H
Sbjct: 410 VLFTDVYTVRETIGVGSYSVCKRCVHKGTNMEYAVKVIDKSKRDPSEEIEILRRYGQHPN 469
Query: 873 VVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQ 694
++ L DVYE+ +IY++ EL GGELLD+++ +K SE+E +++ + V+YLHSQ
Sbjct: 470 IITLKDVYEECNSIYLVTELMRGGELLDRILRQKFF-SEREACSVLFTVCKTVEYLHSQG 528
Query: 693 VAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQG 514
V HRDL +NIL+ + GDP S+RI DFGF+KQ RAENG+LMTPCYTA FVAPEVL++QG
Sbjct: 529 VVHRDLKPSNILYVDESGDPESIRICDFGFSKQLRAENGLLMTPCYTANFVAPEVLKRQG 588
Query: 513 YDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVG 394
YD CD+WSLG+LL+TML G TPFA GP DTP++IL R+G
Sbjct: 589 YDEGCDIWSLGILLYTMLAGYTPFANGPGDTPEEILARIG 628
>gi|24643817|ref|NP_523437.2| CG17596-PA [Drosophila melanogaster]
gi|7295638|gb|AAF50945.1| CG17596-PA [Drosophila melanogaster]
Length = 911
Score = 722 bits (1864), Expect = 0.0
Identities = 381/733 (51%), Positives = 505/733 (67%), Gaps = 45/733 (6%)
Frame = -1
Query: 2148 SETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKA 1972
+E E ++ +V K G +KADP QFELL+VLG+GSFGKVFLVRK+ G+D+G +YAMKVLKKA
Sbjct: 177 TENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKA 236
Query: 1971 TLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMF 1792
TLKV+DR R+ ER ILA + H FIV+LHYAFQT GKLYLILDFLRGGDLFTRLSKEVMF
Sbjct: 237 TLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMF 296
Query: 1791 TEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKT 1612
TE+DVKFY LGI+YRDLKPENILLD GHI +TDFGLSK+ +D KT
Sbjct: 297 TEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDG-SKT 355
Query: 1611 YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKL 1432
YSFCGTVEYMAPE++NR+GH AAD+WS GVLM+EMLTG+LPF G+ R +TM QIL++KL
Sbjct: 356 YSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKL 415
Query: 1431 SMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFK 1252
MP L+ EAQSLLRALFKRN QNRLGAG G+ +IK H FFA ID+V+L K++ PPF
Sbjct: 416 GMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFI 475
Query: 1251 PALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEER----KLIAK 1084
PA+S D YFD E+T ++P+DSP P SA+ HEIFRGFSFV+ ++E + + +
Sbjct: 476 PAVSR-DDAFYFDVEYTSKSPRDSPGGPISASAHEIFRGFSFVAPVLLEGQCAGSNMCST 534
Query: 1083 SV-----------------RSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKY 955
S R++P F +Y +L+++G G SV C+ +A+++ Y
Sbjct: 535 SASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHY 594
Query: 954 AVKIVKKAVF---------DATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGG 802
AVK+++KA D EEV+I+LR+ +H +V L+ VYED + Y++ EL +GG
Sbjct: 595 AVKVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGG 654
Query: 801 ELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLR 622
ELLD+++ + E E +A++ + +AV YLH V HRDL +N+++A P +L+
Sbjct: 655 ELLDRILAVGQM-CESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLK 713
Query: 621 IVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPF 442
+ D GFAKQ RA+NG+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+ ML+G TPF
Sbjct: 714 LCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPF 773
Query: 441 AMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKW 262
A PND+PD IL+R+G G+I T W IS AK+L+R+ML + P R TA + L+H W
Sbjct: 774 ASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARILEHDW 833
Query: 261 IGQKEA----LPDRPI----------QSEQVGELDMQNVKVALEQTYKAIASAPSVQLRP 124
+ ++ A L + + Q +Q + M ++ A++ T++AIA + + P
Sbjct: 834 LREQFAGGVQLTEYAVAPGSQLSLGAQQQQQNHISMA-LRGAVDATFRAIAIPQAANVGP 892
Query: 123 VGSSALAKRRMKE 85
V S LAKRR K+
Sbjct: 893 VELSMLAKRRAKD 905
>gi|455163|gb|AAA50509.1| p90 ribosomal S6 kinase
Length = 910
Score = 722 bits (1864), Expect = 0.0
Identities = 381/733 (51%), Positives = 505/733 (67%), Gaps = 45/733 (6%)
Frame = -1
Query: 2148 SETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKA 1972
+E E ++ +V K G +KADP QFELL+VLG+GSFGKVFLVRK+ G+D+G +YAMKVLKKA
Sbjct: 176 TENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKA 235
Query: 1971 TLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMF 1792
TLKV+DR R+ ER ILA + H FIV+LHYAFQT GKLYLILDFLRGGDLFTRLSKEVMF
Sbjct: 236 TLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMF 295
Query: 1791 TEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKT 1612
TE+DVKFY LGI+YRDLKPENILLD GHI +TDFGLSK+ +D KT
Sbjct: 296 TEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDG-SKT 354
Query: 1611 YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKL 1432
YSFCGTVEYMAPE++NR+GH AAD+WS GVLM+EMLTG+LPF G+ R +TM QIL++KL
Sbjct: 355 YSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKL 414
Query: 1431 SMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFK 1252
MP L+ EAQSLLRALFKRN QNRLGAG G+ +IK H FFA ID+V+L K++ PPF
Sbjct: 415 GMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFI 474
Query: 1251 PALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEER----KLIAK 1084
PA+S D YFD E+T ++P+DSP P SA+ HEIFRGFSFV+ ++E + + +
Sbjct: 475 PAVSR-DDAFYFDVEYTSKSPRDSPGGPISASAHEIFRGFSFVAPVLLEGQCAGSNMCST 533
Query: 1083 SV-----------------RSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKY 955
S R++P F +Y +L+++G G SV C+ +A+++ Y
Sbjct: 534 SASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHY 593
Query: 954 AVKIVKKAVF---------DATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGG 802
AVK+++KA D EEV+I+LR+ +H +V L+ VYED + Y++ EL +GG
Sbjct: 594 AVKVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGG 653
Query: 801 ELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLR 622
ELLD+++ + E E +A++ + +AV YLH V HRDL +N+++A P +L+
Sbjct: 654 ELLDRILAVGQM-CESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLK 712
Query: 621 IVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPF 442
+ D GFAKQ RA+NG+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+ ML+G TPF
Sbjct: 713 LCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPF 772
Query: 441 AMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKW 262
A PND+PD IL+R+G G+I T W IS AK+L+R+ML + P R TA + L+H W
Sbjct: 773 ASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARILEHDW 832
Query: 261 IGQKEA----LPDRPI----------QSEQVGELDMQNVKVALEQTYKAIASAPSVQLRP 124
+ ++ A L + + Q +Q + M ++ A++ T++AIA + + P
Sbjct: 833 LREQFAGGVQLTEYAVAPGSQLSLCAQQQQQNHISMA-LRGAVDATFRAIAIPQAANVGP 891
Query: 123 VGSSALAKRRMKE 85
V S LAKRR K+
Sbjct: 892 VELSMLAKRRAKD 904
>gi|28416327|gb|AAO42636.1| SD05277p [Drosophila melanogaster]
Length = 892
Score = 710 bits (1832), Expect = 0.0
Identities = 373/720 (51%), Positives = 496/720 (68%), Gaps = 45/720 (6%)
Frame = -1
Query: 2148 SETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKA 1972
+E E ++ +V K G +KADP QFELL+VLG+GSFGKVFLVRK+ G+D+G +YAMKVLKKA
Sbjct: 177 TENEFELKEVIKEGHDKADPSQFELLRVLGEGSFGKVFLVRKIIGKDAGTLYAMKVLKKA 236
Query: 1971 TLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMF 1792
TLKV+DR R+ ER ILA + H FIV+LHYAFQT GKLYLILDFLRGGDLFTRLSKEVMF
Sbjct: 237 TLKVKDRVRSTNERKILADVGHAFIVRLHYAFQTPGKLYLILDFLRGGDLFTRLSKEVMF 296
Query: 1791 TEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKT 1612
TE+DVKFY LGI+YRDLKPENILLD GHI +TDFGLSK+ +D KT
Sbjct: 297 TEEDVKFYLAELALAMNHLHTLGIIYRDLKPENILLDEHGHIALTDFGLSKQPLDG-SKT 355
Query: 1611 YSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKL 1432
YSFCGTVEYMAPE++NR+GH AAD+WS GVLM+EMLTG+LPF G+ R +TM QIL++KL
Sbjct: 356 YSFCGTVEYMAPEIVNRKGHDFAADWWSFGVLMYEMLTGNLPFHGQTRQETMNQILRSKL 415
Query: 1431 SMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFK 1252
MP L+ EAQSLLRALFKRN QNRLGAG G+ +IK H FFA ID+V+L K++ PPF
Sbjct: 416 GMPENLSPEAQSLLRALFKRNPQNRLGAGAQGILDIKAHCFFATIDWVRLERKQVRPPFI 475
Query: 1251 PALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEER----KLIAK 1084
PA+S D YFD E+T ++P+DSP P SA+ HEIFRGFSFV+ ++E + + +
Sbjct: 476 PAVSR-DDAFYFDVEYTSKSPRDSPGGPISASAHEIFRGFSFVAPVLLEGQCAGSNMCST 534
Query: 1083 SV-----------------RSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKY 955
S R++P F +Y +L+++G G SV C+ +A+++ Y
Sbjct: 535 SASPLHSIAPIPAAPVGAPRTLPGVLPGNFHAEYNLLQELGRGTFSVCRLCEHRASKKHY 594
Query: 954 AVKIVKKAVF---------DATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGG 802
AVK+++KA D EEV+I+LR+ +H +V L+ VYED + Y++ EL +GG
Sbjct: 595 AVKVIEKAAVAAASTSTSADCWEEVEIMLRYGNHPNIVTLYSVYEDAGSAYLVMELLKGG 654
Query: 801 ELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLR 622
ELLD+++ + E E +A++ + +AV YLH V HRDL +N+++A P +L+
Sbjct: 655 ELLDRILAVGQM-CESEASAVLRTIASAVAYLHEHGVVHRDLKPSNMIYASMRQTPETLK 713
Query: 621 IVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPF 442
+ D GFAKQ RA+NG+LMTPCYTA FVAPEVL++QGYD +CD+WSLGVLL+ ML+G TPF
Sbjct: 714 LCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDLACDIWSLGVLLYIMLSGRTPF 773
Query: 441 AMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKW 262
A PND+PD IL+R+G G+I T W IS AK+L+R+ML + P R TA + L+H W
Sbjct: 774 ASTPNDSPDVILKRIGSGQIDFTSSRWALISVPAKELLRQMLHIVPENRPTAARILEHDW 833
Query: 261 IGQKEA----LPDRPI----------QSEQVGELDMQNVKVALEQTYKAIASAPSVQLRP 124
+ ++ A L + + Q +Q + M ++ A++ T++AIA + + P
Sbjct: 834 LREQFAGGVQLTEYAVAPGSQLSLGAQQQQQNHISMA-LRGAVDATFRAIAIPQAANVGP 892
>gi|47218726|emb|CAG05698.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 694
Score = 702 bits (1813), Expect = 0.0
Identities = 381/728 (52%), Positives = 477/728 (65%), Gaps = 32/728 (4%)
Frame = -1
Query: 2157 DSSSETEIDIGDVRKCG-EKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVL 1981
D S EIDI K G EKADP QF+LLKVLGQGS+GKVFLVRK+RG D G +YAMKVL
Sbjct: 10 DDSILKEIDISHHVKEGCEKADPSQFQLLKVLGQGSYGKVFLVRKIRGVDRGQLYAMKVL 69
Query: 1980 KKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 1801
KKATLKVRDR R+K+ER+ILA ++HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE
Sbjct: 70 KKATLKVRDRVRSKMERDILAEVNHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKE 129
Query: 1800 VMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSE 1621
VMFTE+DVKFY LGI+YRDLKPENILLD DGHIK+TDFGLSKEAID +
Sbjct: 130 VMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEDGHIKITDFGLSKEAIDHD 189
Query: 1620 KKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILK 1441
K+ YSFCGT+EYMAPEV+NRRGH+ +AD+WS GVLM+EMLTG LPFQG+DR +TM ILK
Sbjct: 190 KRAYSFCGTIEYMAPEVVNRRGHTQSADWWSFGVLMYEMLTGSLPFQGKDRKETMALILK 249
Query: 1440 AKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDP 1261
AKL MP FL+ E KL KEI P
Sbjct: 250 AKLGMPQFLSPE---------------------------------------KLYQKEIRP 270
Query: 1260 PFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFV-SNAVMEERKLIAK 1084
PFKP + + T +FDPEFT RTP DSP +P SAN H++FRGFSFV +N + E
Sbjct: 271 PFKPTVGRPEDTFHFDPEFTSRTPTDSPGIPPSANTHQLFRGFSFVATNQIPESTVATVA 330
Query: 1083 SVRSVPTAKTNP----------FTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKK 934
R + NP F+D YE+ E++G SV +C + T +Y+VKI ++
Sbjct: 331 PSRQDVSNPINPISEHLRGDVAFSDVYELKEEVGQTTASVCRRCLHRVTAVEYSVKI-ER 389
Query: 933 AVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEK 754
D +EE++ILLR+ H ++ L DV++D +Y++++L G ELLD+++ +E+
Sbjct: 390 VRKDPSEEIEILLRYGQHPNIINLKDVFDDGQRVYLVQDLLRGEELLDRVLGLPDF-TER 448
Query: 753 EVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGM 574
+ +AIM L V+YLHSQ V HRDL +NI + G P S+RI DF AKQ RAENG+
Sbjct: 449 DASAIMCTLTKTVEYLHSQGVVHRDLKPSNIRYCDDGGLPESIRICDFAVAKQLRAENGL 508
Query: 573 LMTPCYTAQFVAPEVLRKQGYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVG 394
LMTPCYTA F+APE+LRKQGYD +CD+WSLG+LL+TM+ G +PFA DT ++IL ++G
Sbjct: 509 LMTPCYTATFMAPEILRKQGYDAACDIWSLGILLYTMIAGFSPFASSSEDTAEEILAQIG 568
Query: 393 DGKISMTHPVWDTISDEAKDLVRKMLDVDPNRRVTAKQALQHKWIGQKEALPDRPIQSEQ 214
GK+ +T W+ +SD AKD+V KML VDP++R+TA Q L+H WI K L DR + +
Sbjct: 569 SGKVCVTGGNWELVSDAAKDIVTKMLHVDPHQRLTAPQVLRHPWIVDKAQLSDRALTRQ- 627
Query: 213 VGELDMQNVKV-------------------ALEQTYKAI-ASAPSVQLRPVGSSALAKRR 94
D VKV AL TY A+ AP+ L PV +S LA+RR
Sbjct: 628 ----DADTVKVAPSATFSASNGAIVSFHQGALSATYCALRRCAPAPVLEPVQASNLAQRR 683
Query: 93 MKEILYAN 70
+ L +N
Sbjct: 684 GMKNLGSN 691
>gi|401774|gb|AAC82495.1| ribosomal protein S6 kinase 3 [Homo sapiens]
Length = 580
Score = 672 bits (1735), Expect = 0.0
Identities = 344/551 (62%), Positives = 420/551 (75%), Gaps = 10/551 (1%)
Frame = -1
Query: 2172 GEEKTDSSSETEIDIGD------VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRD 2011
GEE+ + +E E+ I + V++ EKADP QFELLKVLGQGSFGKVFLV+K+ G D
Sbjct: 33 GEEEINPQTE-EVSIKEIAITHHVKEGHEKADPSQFELLKVLGQGSFGKVFLVKKISGSD 91
Query: 2010 SGHVYAMKVLKKATLKVRDRQRTKLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRG 1831
+ +YAMKVLKKATLKVRDR RTK+ER+IL ++HPFIVKLHYAFQTEGKLYLILDFLRG
Sbjct: 92 ARQLYAMKVLKKATLKVRDRVRTKMERDILVEVNHPFIVKLHYAFQTEGKLYLILDFLRG 151
Query: 1830 GDLFTRLSKEVMFTEDDVKFYXXXXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDF 1651
GDLFTRLSKEVMFTE+DVKFY LGI+YRDLKPENILLD +GHIK+TDF
Sbjct: 152 GDLFTRLSKEVMFTEEDVKFYLAELALALDHLHSLGIIYRDLKPENILLDEEGHIKLTDF 211
Query: 1650 GLSKEAIDSEKKTYSFCGTVEYMAPEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRD 1471
GLSKE+ID EKK YSFCGTVEYMAPEV+NRRGH+ +AD+WS GVLMFEMLTG LPFQG+D
Sbjct: 212 GLSKESIDHEKKAYSFCGTVEYMAPEVVNRRGHTQSADWWSFGVLMFEMLTGTLPFQGKD 271
Query: 1470 RNDTMTQILKAKLSMPHFLTQEAQSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDF 1291
R +TMT ILKAKL MP FL+ EAQSLLR LFKRN NRLGAGPDGVEEIKRH+FF+ ID+
Sbjct: 272 RKETMTMILKAKLGMPQFLSPEAQSLLRMLFKRNPANRLGAGPDGVEEIKRHSFFSTIDW 331
Query: 1290 VKLLNKEIDPPFKPALSTVDSTSYFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAV 1111
KL +EI PPFKPA + T YFDPEFT +TPKDSP +P SAN H++FRGFSFV+
Sbjct: 332 NKLYRREIHPPFKPATGRPEDTFYFDPEFTAKTPKDSPGIPPSANAHQLFRGFSFVAITS 391
Query: 1110 MEERKLI----AKSVRSVPTAKTNPFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKI 943
+E + + S+ + FTD YE+ E IG G++SV +C KAT ++AVKI
Sbjct: 392 DDESQAMQTVGVHSIVQQLHRNSIQFTDGYELKEDIGVGSYSVCKRCIHKATNMEFAVKI 451
Query: 942 VKKAVFDATEEVDILLRHSHHQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLG 763
+ K+ D TEE++ILLR+ H ++ L DVY+D +Y++ L +GGELLDK++ +K
Sbjct: 452 IDKSKRDPTEEIEILLRYGQHPNIITLNDVYDDGKYVYVV-TLMKGGELLDKILRQKFF- 509
Query: 762 SEKEVAAIMANLLNAVQYLHSQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAE 583
SE+E +A++ + V+YLH+Q V HRDL +NIL+ + G+P S+RI DFGFAKQ RAE
Sbjct: 510 SEREASAVLFTITKTVEYLHAQGVVHRDLKPSNILYVDESGNPESIRICDFGFAKQLRAE 569
Query: 582 NGMLMTPCYTA 550
NG+LMTPCYTA
Sbjct: 570 NGLLMTPCYTA 580
Score = 120 bits (302), Expect = 1e-25
Identities = 82/260 (31%), Positives = 139/260 (52%), Gaps = 10/260 (3%)
Frame = -1
Query: 1035 YEILEKIGNGAHS---VVHKCQMKATRRKYAVKIVKKAVFDATEEV------DILLRHSH 883
+E+L+ +G G+ +V K R+ YA+K++KKA + V DIL+ +
Sbjct: 67 FELLKVLGQGSFGKVFLVKKISGSDARQLYAMKVLKKATLKVRDRVRTKMERDILVE-VN 125
Query: 882 HQFVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLH 703
H F+VKL ++ E +Y+I + GG+L +L +K+ + +E++V +A L A+ +LH
Sbjct: 126 HPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRL-SKEVMFTEEDVKFYLAELALALDHLH 184
Query: 702 SQQVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLR 523
S + +RDL NIL + +++ DFG +K+S + C T +++APEV+
Sbjct: 185 SLGIIYRDLKPENILL----DEEGHIKLTDFGLSKESIDHEKKAYSFCGTVEYMAPEVVN 240
Query: 522 KQGYDRSCDVWSLGVLLHTMLTGCTPF-AMGPNDTPDQILQRVGDGKISMTHPVWDTISD 346
++G+ +S D WS GVL+ MLTG PF +T IL+ K+ M +S
Sbjct: 241 RRGHTQSADWWSFGVLMFEMLTGTLPFQGKDRKETMTMILK----AKLGMP----QFLSP 292
Query: 345 EAKDLVRKMLDVDPNRRVTA 286
EA+ L+R + +P R+ A
Sbjct: 293 EAQSLLRMLFKRNPANRLGA 312
>gi|34881194|ref|XP_228473.2| similar to Ribosomal protein S6 kinase
alpha 6 (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase
6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4)
[Rattus norvegicus]
Length = 659
Score = 654 bits (1688), Expect = 0.0
Identities = 335/600 (55%), Positives = 428/600 (70%), Gaps = 5/600 (0%)
Frame = -1
Query: 2121 VRKCGEKADPRQFELLKVLGQGSFGKVFLVRKVRGRDSGHVYAMKVLKKATLKVRDRQRT 1942
V++ EKADP QF+LLKVLGQGSFGKVFLVRK G D+G +YAMKVL+KA+LKVRDR RT
Sbjct: 99 VKEGYEKADPAQFDLLKVLGQGSFGKVFLVRKKTGPDAGQLYAMKVLRKASLKVRDRVRT 158
Query: 1941 KLERNILAHISHPFIVKLHYAFQTEGKLYLILDFLRGGDLFTRLSKEVMFTEDDVKFYXX 1762
K+ER+IL ++HPFIVKLHY E+DVKFY
Sbjct: 159 KMERDILVEVNHPFIVKLHY-------------------------------EEDVKFYLA 187
Query: 1761 XXXXXXXXXXXLGIVYRDLKPENILLDADGHIKVTDFGLSKEAIDSEKKTYSFCGTVEYM 1582
LGIVYRDLKPENILLD GHIK+TDFGLSKE++D EKK YSFCGTVEYM
Sbjct: 188 ELALALDHLHRLGIVYRDLKPENILLDEIGHIKLTDFGLSKESVDQEKKAYSFCGTVEYM 247
Query: 1581 APEVINRRGHSMAADFWSLGVLMFEMLTGHLPFQGRDRNDTMTQILKAKLSMPHFLTQEA 1402
APEV+NRRGHS +AD+WS GVLMFEMLTG LPFQG+DRN+TM ILKAKL MP FL+ EA
Sbjct: 248 APEVVNRRGHSQSADWWSYGVLMFEMLTGTLPFQGKDRNETMNMILKAKLGMPQFLSAEA 307
Query: 1401 QSLLRALFKRNSQNRLGAGPDGVEEIKRHAFFAKIDFVKLLNKEIDPPFKPALSTVDSTS 1222
QSLLR LFKRN NRLG+ +GVEE+KRHAFF+ ID+ KL +E+ PPF+PA D T
Sbjct: 308 QSLLRMLFKRNPANRLGS--EGVEEVKRHAFFSSIDWNKLYKREVQPPFRPASGKPDDTF 365
Query: 1221 YFDPEFTKRTPKDSPALPASANGHEIFRGFSFVSNAVMEERKLI-AKSVRSVPTAKTN-- 1051
FDPEFT +TPK ASAN H++F+GFSFV+ ++ EE K+ S +P + N
Sbjct: 366 CFDPEFTAKTPK------ASANAHQLFKGFSFVATSIAEEYKITPVTSSNVLPIVQINGN 419
Query: 1050 --PFTDDYEILEKIGNGAHSVVHKCQMKATRRKYAVKIVKKAVFDATEEVDILLRHSHHQ 877
F++ YE+ E IG G++SV +C A+ ++AVKI+ K D +EE++IL+R+ H
Sbjct: 420 AAQFSEAYELKEDIGIGSYSVCKRCIHSASNMEFAVKIIDKNKRDPSEEIEILMRYGQHP 479
Query: 876 FVVKLFDVYEDETAIYMIEELCEGGELLDKLVNKKSLGSEKEVAAIMANLLNAVQYLHSQ 697
++ L +V++D +Y++ +L +GGELLD+++ KK SE+E + ++ + V+YLHSQ
Sbjct: 480 NIISLKEVFDDGKYVYLVTDLMKGGELLDRILKKKCF-SEQEASNVLYVITKTVEYLHSQ 538
Query: 696 QVAHRDLTAANILFALKDGDPSSLRIVDFGFAKQSRAENGMLMTPCYTAQFVAPEVLRKQ 517
V HRDL +NIL+ + G P S++I DFGFAKQ R ENG+L+TPCYTA FVAPEVL +Q
Sbjct: 539 GVVHRDLKPSNILYMDESGHPDSIKICDFGFAKQLRGENGLLLTPCYTANFVAPEVLTQQ 598
Query: 516 GYDRSCDVWSLGVLLHTMLTGCTPFAMGPNDTPDQILQRVGDGKISMTHPVWDTISDEAK 337
GYD +CD+WSLGVLL+TML G TPF+ GPNDTP++IL R+G+G+ S++ +WD IS AK
Sbjct: 599 GYDAACDIWSLGVLLYTMLAGYTPFSNGPNDTPEEILLRIGNGRFSLSGGIWDNISRGAK 658