Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= K11C4_2
(6774 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|17562506|ref|NP_504748.1| beta-G spectrin, UNCoordinated loco... 4323 0.0
gi|17976528|gb|AAK77612.2| Uncoordinated protein 70, isoform b [... 4302 0.0
gi|5734146|gb|AAD49858.1| beta-G spectrin [Caenorhabditis elegans] 4302 0.0
gi|7505762|pir||T29140 hypothetical protein K11C4.3 - Caenorhabd... 4259 0.0
gi|39594389|emb|CAE71967.1| Hypothetical protein CBG19038 [Caeno... 4217 0.0
gi|25154697|ref|NP_504749.2| beta-G spectrin, UNCoordinated loco... 4065 0.0
gi|15213122|gb|AAK85734.1| beta-G spectrin [Brugia malayi] 3386 0.0
gi|17647191|ref|NP_523388.1| CG5870-PA [Drosophila melanogaster]... 2502 0.0
gi|423777|pir||A46147 spectrin beta chain - fruit fly (Drosophil... 2502 0.0
gi|31201697|ref|XP_309796.1| ENSANGP00000012507 [Anopheles gambi... 2487 0.0
gi|48101779|ref|XP_395212.1| similar to ENSANGP00000012507 [Apis... 2453 0.0
gi|31201699|ref|XP_309797.1| ENSANGP00000023406 [Anopheles gambi... 2414 0.0
gi|4507195|ref|NP_003119.1| spectrin, beta, non-erythrocytic 1 i... 2241 0.0
gi|33303722|gb|AAQ02380.1| non-erythroid spectrin beta [Rattus n... 2214 0.0
gi|30348966|ref|NP_787030.1| spectrin beta 2 isoform 1; beta-spe... 2206 0.0
gi|34879632|ref|XP_240072.2| similar to Spectrin beta chain, bra... 2196 0.0
gi|50738496|ref|XP_419291.1| PREDICTED: similar to Spectrin beta... 2171 0.0
gi|30315658|ref|NP_842565.1| spectrin, beta, non-erythrocytic 1 ... 2162 0.0
gi|7106421|ref|NP_033286.1| spectrin beta 2 isoform 2; beta-spec... 2159 0.0
gi|448251|prf||1916380A beta spectrin (beta fodrin) 2145 0.0
gi|18859423|ref|NP_571600.1| spectrin, beta, erythrocytic; beta-... 2013 0.0
gi|47209542|emb|CAF96656.1| unnamed protein product [Tetraodon n... 1970 0.0
gi|47227240|emb|CAG00602.1| unnamed protein product [Tetraodon n... 1949 0.0
gi|5902122|ref|NP_008877.1| spectrin, beta, non-erythrocytic 2 [... 1919 0.0
gi|17367415|sp|Q9QWN8|SPCP_RAT Spectrin beta chain, brain 2 (Spe... 1916 0.0
gi|9507135|ref|NP_062040.1| beta-spectrin 3 [Rattus norvegicus] ... 1910 0.0
gi|11066461|gb|AAG28596.1| spectrin-like protein GTRAP41 [Rattus... 1907 0.0
gi|38084794|ref|XP_129130.3| spectrin beta 3 [Mus musculus] 1899 0.0
gi|27413156|ref|NP_000338.2| spectrin, beta, erythrocytic (inclu... 1886 0.0
gi|134798|sp|P11277|SPCB_HUMAN Spectrin beta chain, erythrocyte ... 1882 0.0
gi|338440|gb|AAA60578.1| spectrin Rouen (beta-220-218) mutant co... 1874 0.0
gi|47058982|ref|NP_997687.1| erythroid spectrin beta [Rattus nor... 1868 0.0
gi|50300486|ref|NP_038703.2| spectrin beta 1; beta-spectrin 1; s... 1863 0.0
gi|34866100|ref|XP_234322.2| similar to Spectrin beta chain, ery... 1863 0.0
gi|2506246|sp|P15508|SPCB_MOUSE Spectrin beta chain, erythrocyte... 1838 0.0
gi|47221201|emb|CAG13137.1| unnamed protein product [Tetraodon n... 1833 0.0
gi|40216167|gb|AAR82828.1| AT24411p [Drosophila melanogaster] 1634 0.0
gi|30794220|ref|NP_115999.1| spectrin beta 4; beta-spectrin 4; q... 1546 0.0
gi|11992162|gb|AAG42473.1| spectrin beta IV [Homo sapiens] 1541 0.0
gi|17368942|sp|Q9H254|SPCQ_HUMAN Spectrin beta chain, brain 3 (S... 1541 0.0
gi|16117405|gb|AAK38731.1| beta4-spectrin [Mus musculus] >gnl|BL... 1539 0.0
gi|13435161|ref|NP_079489.1| spectrin, beta, non-erythrocytic 4 ... 1533 0.0
gi|40353204|ref|NP_066022.1| spectrin, beta, non-erythrocytic 4 ... 1531 0.0
gi|11602890|gb|AAF93173.1| betaIV spectrin isoform sigma4 [Homo ... 1528 0.0
gi|34855389|ref|XP_218364.2| similar to betaIV-spectrin sigma1 [... 1417 0.0
gi|33340563|gb|AAQ14859.1| beta spectrin IV [Homo sapiens] 1387 0.0
gi|50510447|dbj|BAD32209.1| mKIAA0302 protein [Mus musculus] 1334 0.0
gi|476928|pir||A47213 beta-fodrin - human (fragment) >gnl|BL_ORD... 1164 0.0
gi|28277312|gb|AAH46267.1| LOC398511 protein [Xenopus laevis] 1072 0.0
gi|10047361|dbj|BAB13468.1| KIAA1642 protein [Homo sapiens] 1061 0.0
gi|47210379|emb|CAF95574.1| unnamed protein product [Tetraodon n... 1059 0.0
gi|47221024|emb|CAG12718.1| unnamed protein product [Tetraodon n... 1031 0.0
gi|24656802|ref|NP_523900.1| CG12008-PA [Drosophila melanogaster... 989 0.0
gi|45552923|ref|NP_995988.1| CG12008-PB [Drosophila melanogaster... 989 0.0
gi|45552921|ref|NP_995987.1| CG12008-PC [Drosophila melanogaster... 989 0.0
gi|50748191|ref|XP_421149.1| PREDICTED: similar to Spectrin beta... 980 0.0
gi|226515|prf||1516310A beta spectrin 966 0.0
gi|11602887|gb|AAF93171.1| betaIV spectrin isoform sigma2 [Homo ... 936 0.0
gi|338330|gb|AAA63259.1| muscle beta spectrin 924 0.0
gi|48136657|ref|XP_396777.1| similar to ENSANGP00000017034 [Apis... 904 0.0
gi|39592126|emb|CAE75346.1| Hypothetical protein CBG23326 [Caeno... 883 0.0
gi|7706190|ref|NP_057726.1| spectrin, beta, non-erythrocytic 5; ... 844 0.0
gi|31209523|ref|XP_313728.1| ENSANGP00000017034 [Anopheles gambi... 830 0.0
gi|7655|emb|CAA37939.1| betaH spectrin [Drosophila melanogaster] 730 0.0
gi|103502|pir||A37792 spectrin beta-H chain - fruit fly (Drosoph... 718 0.0
gi|34856723|ref|XP_238278.2| similar to Spectrin beta chain, bra... 698 0.0
gi|25155104|ref|NP_741632.1| SMAll body size SMA-1, betaH chain ... 691 0.0
gi|7506776|pir||T23630 hypothetical protein R31.1 - Caenorhabdit... 691 0.0
gi|47477769|gb|AAH70885.1| Spna2 protein [Rattus norvegicus] 660 0.0
gi|18481635|gb|AAL73492.1| beta I spectrin form betaI sigma3 [Ho... 648 0.0
gi|31565122|gb|AAH53521.1| SPTAN1 protein [Homo sapiens] 644 0.0
gi|11602888|gb|AAF93172.1| betaIV spectrin isoform sigma3 [Homo ... 603 e-170
gi|444793|prf||1908227A beta spectrin 578 e-163
gi|420115|pir||S29854 spectrin beta chain - dog (fragment) >gnl|... 572 e-161
gi|18147604|dbj|BAB83244.1| betaIV-spectrin sigma6-A [Mus muscul... 565 e-159
gi|31218879|ref|XP_316724.1| ENSANGP00000002653 [Anopheles gambi... 560 e-157
gi|17136504|ref|NP_476739.1| CG1977-PA [Drosophila melanogaster]... 549 e-154
gi|103399|pir||A33733 spectrin alpha chain - fruit fly (Drosophi... 549 e-154
gi|31543764|ref|NP_741984.2| alpha-spectrin 2; alpha-fodrin; noe... 544 e-152
gi|34852958|ref|XP_346648.1| hypothetical protein XP_346647 [Rat... 544 e-152
gi|17380501|sp|P16086|SPCN_RAT Spectrin alpha chain, brain (Spec... 544 e-152
gi|1805280|gb|AAB41498.1| alpha II spectrin [Homo sapiens] 542 e-152
gi|50757376|ref|XP_415495.1| PREDICTED: similar to spectrin alph... 540 e-151
gi|4507191|ref|NP_003118.1| spectrin, alpha, non-erythrocytic 1 ... 539 e-151
gi|134800|sp|P07751|SPCN_CHICK Spectrin alpha chain, brain (Spec... 537 e-150
gi|1334744|emb|CAA32663.1| spectrin alpha chain [Gallus gallus] 531 e-148
gi|38075670|ref|XP_141326.3| similar to Spectrin beta chain, bra... 516 e-144
gi|38074607|ref|XP_207079.2| spectrin alpha 2 [Mus musculus] 515 e-144
gi|34880958|ref|XP_222913.2| similar to erythroid alpha-spectrin... 511 e-143
gi|19526481|ref|NP_035595.2| spectrin alpha 1; alpha-spectrin 1,... 506 e-141
gi|17380523|sp|P08032|SPCA_MOUSE Spectrin alpha chain, erythrocy... 503 e-140
gi|29179635|gb|AAH48851.1| Similar to beta-spectrin 3 [Mus muscu... 482 e-134
gi|39597692|emb|CAE68383.1| Hypothetical protein CBG14139 [Caeno... 471 e-131
gi|50803149|ref|XP_424262.1| PREDICTED: similar to spectrin, bet... 470 e-130
gi|17569483|ref|NP_508537.1| spectrin (spc-1) [Caenorhabditis el... 468 e-129
gi|50747531|ref|XP_426369.1| PREDICTED: similar to unc93 homolog... 457 e-126
gi|7512790|pir||T14790 hypothetical protein DKFZp564P0562.1 - hu... 443 e-122
gi|33303718|gb|AAQ02378.1| erythroid spectrin alpha [Rattus norv... 441 e-122
gi|46577681|sp|P16546|SPCN_MOUSE Spectrin alpha chain, brain (Sp... 436 e-120
gi|4507189|ref|NP_003117.1| spectrin, alpha, erythrocytic 1 (ell... 426 e-117
gi|1174412|sp|P02549|SPCA_HUMAN Spectrin alpha chain, erythrocyt... 426 e-117
gi|11992164|gb|AAG42474.1| spectrin beta IV [Homo sapiens] 422 e-116
gi|20380003|gb|AAH27791.1| Spna2 protein [Mus musculus] 417 e-114
gi|11230802|ref|NP_068695.1| actinin alpha 4 [Mus musculus] >gnl... 415 e-114
gi|47211130|emb|CAF90368.1| unnamed protein product [Tetraodon n... 414 e-113
gi|12025678|ref|NP_004915.2| actinin, alpha 4 [Homo sapiens] >gn... 414 e-113
gi|41054603|ref|NP_955880.1| actinin alpha 4; wu:fb53f05 [Danio ... 414 e-113
gi|50418010|gb|AAH77918.1| Unknown (protein for MGC:80841) [Xeno... 414 e-113
gi|45384104|ref|NP_990457.1| alpha-actinin [Gallus gallus] >gnl|... 414 e-113
gi|2804273|dbj|BAA24447.1| alpha actinin 4 [Homo sapiens] 414 e-113
gi|13123941|sp|Q9QXQ0|AAC4_RAT Alpha-actinin 4 (Non-muscle alpha... 413 e-113
gi|38197444|gb|AAH61788.1| Actn4 protein [Rattus norvegicus] 412 e-113
gi|49903350|gb|AAH76687.1| Unknown (protein for MGC:79707) [Xeno... 412 e-113
gi|539494|pir||A42162 alpha-actinin 1 - chicken >gnl|BL_ORD_ID|5... 411 e-112
gi|31242387|ref|XP_321624.1| ENSANGP00000011796 [Anopheles gambi... 411 e-112
gi|13124665|sp|P05094|AAC1_CHICK Alpha-actinin 1 (Alpha-actinin ... 410 e-112
gi|47124694|gb|AAH70594.1| MGC81191 protein [Xenopus laevis] 409 e-112
gi|24639240|ref|NP_726784.1| CG4376-PB [Drosophila melanogaster]... 408 e-112
gi|49903986|gb|AAH76640.1| Unknown (protein for MGC:78775) [Xeno... 408 e-112
gi|13591902|ref|NP_112267.1| actinin, alpha 1; non-muscle alpha-... 408 e-111
gi|32449722|gb|AAH43995.2| ACTN1 protein [Xenopus laevis] 408 e-111
gi|38018016|gb|AAR08137.1| brain-specific alpha actinin 1 isofor... 408 e-111
gi|17565034|ref|NP_506128.1| actinin (104.1 kD) (atn-1) [Caenorh... 408 e-111
gi|49256643|gb|AAH74001.1| Actn1 protein [Rattus norvegicus] 408 e-111
gi|45387533|ref|NP_991107.1| Unknown (protein for MGC:77243); wu... 407 e-111
gi|25992501|gb|AAN77132.1| alpha-actinin [Danio rerio] >gnl|BL_O... 407 e-111
gi|46395721|sp|Q7TPR4|AAC1_MOUSE Alpha-actinin 1 (Alpha-actinin ... 406 e-111
gi|8186|emb|CAA36042.1| unnamed protein product [Drosophila mela... 406 e-111
gi|47169151|pdb|1SJJ|A Chain A, Cryo-Em Structure Of Chicken Giz... 406 e-111
gi|45383852|ref|NP_989458.1| actinin, alpha 1 [Gallus gallus] >g... 406 e-111
gi|1070611|pir||FAFFAA alpha-actinin - fruit fly (Drosophila mel... 406 e-111
gi|4501891|ref|NP_001093.1| actinin, alpha 1 [Homo sapiens] >gnl... 405 e-111
gi|625303|pir||FAHUAA alpha-actinin 1 - human >gnl|BL_ORD_ID|674... 405 e-111
gi|50417651|gb|AAH77752.1| Unknown (protein for MGC:79035) [Xeno... 405 e-111
gi|30585329|gb|AAP36937.1| Homo sapiens actinin, alpha 1 [synthe... 405 e-111
gi|24639238|ref|NP_477484.2| CG4376-PA [Drosophila melanogaster]... 405 e-111
gi|4501893|ref|NP_001094.1| actinin, alpha 2 [Homo sapiens] >gnl... 405 e-111
gi|34876265|ref|XP_214499.2| similar to actinin, alpha 2 [Rattus... 405 e-111
gi|4557241|ref|NP_001095.1| skeletal muscle specific actinin, al... 405 e-111
gi|31981445|ref|NP_150371.2| actinin alpha 2 [Mus musculus] >gnl... 405 e-111
gi|39592275|emb|CAE75496.1| Hypothetical protein CBG23504 [Caeno... 404 e-110
gi|19173800|ref|NP_596915.1| actinin alpha 3 [Rattus norvegicus]... 404 e-110
gi|7304855|ref|NP_038484.1| actinin alpha 3 [Mus musculus] >gnl|... 404 e-110
gi|47212235|emb|CAF96202.1| unnamed protein product [Tetraodon n... 404 e-110
gi|47939926|gb|AAH72105.1| MGC79034 protein [Xenopus laevis] >gn... 404 e-110
gi|6446579|gb|AAA21249.2| beta-heavy-spectrin [Drosophila melano... 404 e-110
gi|63389|emb|CAA32079.1| fibroblast alpha actinin [Gallus gallus] 404 e-110
gi|46048687|ref|NP_990654.1| alpha-actinin [Gallus gallus] >gnl|... 403 e-110
gi|20853961|gb|AAM26632.1| truncated alpha-actinin [Rattus norve... 402 e-110
gi|49899924|gb|AAH76938.1| Unknown (protein for MGC:89234) [Xeno... 402 e-110
gi|47155482|dbj|BAD18923.1| alpha 3 actinin [Equus caballus] 402 e-110
gi|28193204|emb|CAD62344.1| unnamed protein product [Homo sapiens] 401 e-109
gi|32766313|gb|AAH54911.1| Zgc:63559 protein [Danio rerio] 400 e-109
gi|23394914|gb|AAN31639.1| alpha-actinin [Biomphalaria glabrata] 400 e-109
gi|13123947|sp|Q9JI91|AAC2_MOUSE Alpha-actinin 2 (Alpha actinin ... 398 e-108
gi|3157976|gb|AAC17470.1| alpha actinin [Homo sapiens] 398 e-108
gi|13928936|ref|NP_113863.1| alpha actinin 4; alpha actinin 4, b... 396 e-108
gi|37362178|gb|AAQ91217.1| actinin, alpha 2 [Danio rerio] 396 e-108
gi|17137758|ref|NP_477485.1| CG4376-PC [Drosophila melanogaster]... 395 e-108
gi|13124689|sp|P18091|AACT_DROME Alpha-actinin, sarcomeric (F-ac... 394 e-107
gi|47224786|emb|CAG06356.1| unnamed protein product [Tetraodon n... 391 e-106
gi|17565036|ref|NP_506127.1| actinin (107.2 kD) (atn-1) [Caenorh... 385 e-105
gi|47218150|emb|CAG10070.1| unnamed protein product [Tetraodon n... 385 e-104
gi|477205|pir||A48403 alpha-actinin - Caenorhabditis elegans (fr... 384 e-104
gi|555419|gb|AAA48566.1| alpha-actinin 382 e-104
gi|7441355|pir||S61217 spectrin alpha II chain - rat (fragment) 374 e-101
gi|31242389|ref|XP_321625.1| ENSANGP00000023605 [Anopheles gambi... 372 e-101
gi|21429122|gb|AAM50280.1| LP04011p [Drosophila melanogaster] 367 3e-99
gi|6690788|gb|AAF24343.1| Short stop/Kakapo long isoform [Drosop... 364 2e-98
gi|24653491|ref|NP_725337.1| CG18076-PE [Drosophila melanogaster... 363 3e-98
gi|47206713|emb|CAF90950.1| unnamed protein product [Tetraodon n... 357 3e-96
gi|26342072|dbj|BAC34698.1| unnamed protein product [Mus musculus] 355 9e-96
gi|3758911|emb|CAA09870.1| Kakapo [Drosophila melanogaster] 352 6e-95
gi|24653489|ref|NP_725336.1| CG18076-PB [Drosophila melanogaster... 351 1e-94
gi|24653487|ref|NP_725335.1| CG18076-PG [Drosophila melanogaster... 351 1e-94
gi|178426|gb|AAA51702.1| alpha-fodrin >gnl|BL_ORD_ID|114424 gi|5... 350 2e-94
gi|7511951|pir||T13714 kakapo gene protein - fruit fly (Drosophi... 350 3e-94
gi|47155480|dbj|BAD18922.1| alpha 2 actinin [Equus caballus] 350 4e-94
gi|24653493|ref|NP_523733.2| CG18076-PA [Drosophila melanogaster... 349 6e-94
gi|2345081|gb|AAC02791.1| beta-spectrin [Homo sapiens] 349 6e-94
gi|48123513|ref|XP_393253.1| similar to Alpha-actinin, sarcomeri... 348 8e-94
gi|92758|pir||A32612 spectrin alpha chain, nonerythroid - rat (f... 347 3e-93
gi|31227668|ref|XP_317923.1| ENSANGP00000011373 [Anopheles gambi... 336 4e-90
gi|112957|sp|P05095|AACT_DICDI Alpha-actinin, non-muscular (F-ac... 333 5e-89
gi|2655084|gb|AAB87867.1| beta-H spectrin [Drosophila melanogaster] 331 2e-88
gi|29387027|gb|AAH48220.1| LOC398587 protein [Xenopus laevis] 304 2e-80
gi|41322908|ref|NP_958781.1| plectin 1 isoform 3; hemidesmosomal... 304 2e-80
gi|47211129|emb|CAF90367.1| unnamed protein product [Tetraodon n... 304 2e-80
gi|47208193|emb|CAF95915.1| unnamed protein product [Tetraodon n... 304 2e-80
gi|47607492|ref|NP_000436.2| plectin 1 isoform 1; hemidesmosomal... 303 3e-80
gi|7442004|pir||G02520 plectin - human >gnl|BL_ORD_ID|215627 gi|... 303 4e-80
gi|41322910|ref|NP_958783.1| plectin 1 isoform 7; hemidesmosomal... 302 7e-80
gi|41322912|ref|NP_958780.1| plectin 1 isoform 2; hemidesmosomal... 302 9e-80
gi|41322904|ref|NP_035247.1| plectin 1 isoform 1 [Mus musculus] ... 301 2e-79
gi|41322921|ref|NP_958788.1| plectin 1 isoform 3 [Mus musculus] ... 301 2e-79
gi|41322914|ref|NP_958785.1| plectin 1 isoform 10; hemidesmosoma... 300 2e-79
gi|41322919|ref|NP_958784.1| plectin 1 isoform 8; hemidesmosomal... 300 2e-79
gi|41322923|ref|NP_958786.1| plectin 1 isoform 11; hemidesmosoma... 300 2e-79
gi|41322916|ref|NP_958782.1| plectin 1 isoform 6; hemidesmosomal... 300 2e-79
gi|14195007|sp|Q15149|PLE1_HUMAN Plectin 1 (PLTN) (PCN) (Hemides... 300 3e-79
gi|41322933|ref|NP_958792.1| plectin 1 isoform 7 [Mus musculus] ... 300 4e-79
gi|11276931|pir||T42694 hypothetical protein DKFZp434J0328.1 - h... 300 4e-79
gi|40849890|gb|AAR95657.1| plectin 3 [Rattus norvegicus] 299 6e-79
gi|41322925|ref|NP_958787.1| plectin 1 isoform 2 [Mus musculus] ... 299 6e-79
gi|40849886|gb|AAR95655.1| plectin 1 [Rattus norvegicus] 299 6e-79
gi|38074605|ref|XP_355324.1| similar to Spectrin alpha chain, br... 298 1e-78
gi|40849898|gb|AAR95661.1| plectin 7 [Rattus norvegicus] 298 1e-78
gi|41322939|ref|NP_958795.1| plectin 1 isoform 10 [Mus musculus]... 298 2e-78
gi|41322931|ref|NP_958791.1| plectin 1 isoform 6 [Mus musculus] ... 298 2e-78
gi|40849888|gb|AAR95656.1| plectin 2 [Rattus norvegicus] 298 2e-78
gi|41322941|ref|NP_958796.1| plectin 1 isoform 11 [Mus musculus]... 298 2e-78
gi|41322935|ref|NP_958793.1| plectin 1 isoform 8 [Mus musculus] ... 298 2e-78
gi|239922|gb|AAB20540.1| beta-spectrin subunit [mice, brain, Pep... 296 4e-78
gi|40849904|gb|AAR95664.1| plectin 10 [Rattus norvegicus] 296 5e-78
gi|40849906|gb|AAR95665.1| plectin 11 [Rattus norvegicus] 296 5e-78
gi|40849900|gb|AAR95662.1| plectin 8 [Rattus norvegicus] 296 5e-78
gi|40849896|gb|AAR95660.1| plectin 6 [Rattus norvegicus] 296 5e-78
gi|14195014|sp|Q9QXS1|PLE1_MOUSE Plectin 1 (PLTN) (PCN) >gnl|BL_... 291 1e-76
gi|38077809|ref|XP_354920.1| similar to plectin [Mus musculus] 291 1e-76
gi|13540714|ref|NP_071796.1| plectin [Rattus norvegicus] >gnl|BL... 291 2e-76
gi|6578747|gb|AAF18074.1| plectin isoform plec 0,1c [Mus musculus] 286 5e-75
gi|929034|emb|CAA27855.1| unnamed protein product [Dictyostelium... 284 2e-74
gi|27923959|sp|Q03001|BPA1_HUMAN Bullous pemphigoid antigen 1 is... 283 3e-74
gi|6578743|gb|AAF18072.1| plectin isoform plec 1b [Mus musculus] 283 4e-74
gi|161334|gb|AAA30008.1| alpha-spectrin 283 4e-74
gi|30315911|sp||Q60824_1 [Segment 1 of 2] Bullous pemphigoid ant... 282 9e-74
gi|2135049|pir||I39160 dystonin isoform 1 - human (fragment) >gn... 281 2e-73
gi|34577047|ref|NP_899236.1| bullous pemphigoid antigen 1 isofor... 281 2e-73
gi|19882221|ref|NP_604443.1| dystonin isoform b; bullous pemphig... 280 5e-73
gi|2137272|pir||I49290 dystonin - mouse (fragment) >gnl|BL_ORD_I... 280 5e-73
gi|19882219|ref|NP_598594.1| dystonin isoform a; bullous pemphig... 280 5e-73
gi|6578741|gb|AAF18071.1| plectin isoform plec 1b,2alpha [Mus mu... 277 3e-72
gi|26336595|dbj|BAC31980.1| unnamed protein product [Mus musculus] 276 4e-72
gi|6578745|gb|AAF18073.1| plectin isoform plec 0,1c,2alpha,3alph... 276 7e-72
gi|6273778|gb|AAF06360.1| trabeculin-alpha [Homo sapiens] 269 8e-70
gi|47209281|emb|CAF94415.1| unnamed protein product [Tetraodon n... 269 8e-70
gi|46125813|ref|XP_387460.1| hypothetical protein FG07284.1 [Gib... 268 2e-69
gi|19115207|ref|NP_594295.1| hypothetical protein [Schizosacchar... 267 3e-69
gi|14285345|sp|Q9UPN3|MACF_HUMAN Microtubule-actin crosslinking ... 265 1e-68
gi|5821434|dbj|BAA83821.1| actin binding protein ABP620 [Homo sa... 265 1e-68
gi|33188445|ref|NP_036222.3| microfilament and actin filament cr... 265 1e-68
gi|39588961|emb|CAE69591.1| Hypothetical protein CBG15813 [Caeno... 263 4e-68
gi|25021548|ref|XP_110503.2| microtubule-actin crosslinking fact... 262 8e-68
gi|109157|pir||S17548 alpha-actinin - rabbit (fragment) >gnl|BL_... 261 1e-67
gi|7513586|pir||T30847 actin binding protein ACF7, neural isofor... 260 3e-67
gi|14285343|sp|Q9QXZ0|MACF_MOUSE Microtubule-actin crosslinking ... 260 3e-67
gi|6005938|ref|NP_009055.1| utrophin; dystrophin-related protein... 260 4e-67
gi|836669|gb|AAB60364.1| alpha II spectrin [Homo sapiens] 259 6e-67
gi|5032281|ref|NP_000100.2| dystrophin Dp427c isoform; dystrophi... 258 2e-66
gi|11360345|pir||T42725 actin binding protein ACF7, neural isofo... 258 2e-66
gi|5032287|ref|NP_004000.1| dystrophin Dp427p1 isoform; dystroph... 258 2e-66
gi|32411607|ref|XP_326284.1| hypothetical protein [Neurospora cr... 256 4e-66
gi|6681203|ref|NP_031894.1| dystrophin, muscular dystrophy; Duch... 256 5e-66
gi|1169358|sp|P11531|DMD_MOUSE Dystrophin >gnl|BL_ORD_ID|327534 ... 256 5e-66
gi|38110842|gb|EAA56504.1| hypothetical protein MG06475.4 [Magna... 256 5e-66
gi|118685|sp|P11532|DMD_HUMAN Dystrophin 255 1e-65
gi|5032283|ref|NP_003997.1| dystrophin Dp427m isoform; dystrophi... 255 1e-65
gi|87340|pir||A27605 dystrophin, muscle - human >gnl|BL_ORD_ID|8... 255 1e-65
gi|30846|emb|CAA32479.1| unnamed protein product [Homo sapiens] 255 1e-65
gi|46575908|ref|NP_035812.2| utrophin; G-utrophin [Mus musculus]... 252 1e-64
gi|2134687|pir||S66292 actin-crosslinking protein ACF7 - human (... 251 2e-64
gi|17511185|ref|NP_492998.1| VAB-10A protein family member, Vari... 249 9e-64
gi|27801760|emb|CAD44516.1| VAB-10B protein [Caenorhabditis eleg... 248 1e-63
gi|50470589|emb|CAH04759.1| Hypothetical protein ZK1151.1g [Caen... 248 1e-63
gi|27763989|emb|CAD44324.1| VAB-10B protein [Caenorhabditis eleg... 248 1e-63
gi|27763987|emb|CAD44323.1| VAB-10A protein [Caenorhabditis eleg... 248 1e-63
gi|27801758|emb|CAD44515.1| VAB-10A protein [Caenorhabditis eleg... 248 1e-63
gi|27801756|emb|CAD44514.1| VAB-10A protein [Caenorhabditis eleg... 248 1e-63
gi|33300472|emb|CAD90188.2| Hypothetical protein ZK1151.1c [Caen... 248 1e-63
gi|50507817|emb|CAH04710.1| Hypothetical protein ZK1151.1f [Caen... 248 1e-63
gi|6981696|ref|NP_037202.1| utrophin; utrophin (homologous to dy... 246 4e-63
gi|7510924|pir||T22552 hypothetical protein ZK1151.1 - Caenorhab... 244 2e-62
gi|14195008|sp|Q9JI55|PLE1_CRIGR Plectin 1 (PLTN) (PCN) (300-kDa... 244 3e-62
gi|49111879|ref|XP_411844.1| hypothetical protein AN7707.2 [Aspe... 240 3e-61
gi|49075768|ref|XP_401927.1| hypothetical protein UM04312.1 [Ust... 239 9e-61
gi|24653495|ref|NP_725338.1| CG18076-PC [Drosophila melanogaster... 238 1e-60
gi|47550975|ref|NP_999661.1| dystrophin-like protein [Strongyloc... 236 6e-60
gi|13430206|gb|AAK25769.1| non-erythrocyte beta-spectrin [Rattus... 235 1e-59
gi|33357326|pdb|1MB8|A Chain A, Crystal Structure Of The Actin B... 234 2e-59
gi|49258991|pdb|1SH5|A Chain A, Crystal Structure Of Actin-Bindi... 234 3e-59
gi|41322927|ref|NP_958789.1| plectin 1 isoform 4 [Mus musculus] ... 233 5e-59
gi|40849892|gb|AAR95658.1| plectin 4 [Rattus norvegicus] >gnl|BL... 231 1e-58
gi|85771|pir||S01092 fodrin alpha chain (clone alpha-2) - Africa... 229 9e-58
gi|24653497|ref|NP_725339.1| CG18076-PH [Drosophila melanogaster... 224 2e-56
gi|482422|pir||A45929 spectrin beta chain - mouse (fragment) 223 7e-56
gi|554276|gb|AAA40126.1| beta-spectrin 221 3e-55
gi|30315803|emb|CAD67584.1| putative dystrophin [Takifugu rubripes] 220 3e-55
gi|2345079|gb|AAC02789.1| beta-spectrin [Homo sapiens] 220 4e-55
gi|50555435|ref|XP_505126.1| hypothetical protein [Yarrowia lipo... 220 4e-55
gi|50507816|emb|CAH04709.1| Hypothetical protein ZK1151.1e [Caen... 219 1e-54
gi|6578761|gb|AAF18081.1| plectin isoform plec 1h [Mus musculus]... 218 1e-54
gi|47218666|emb|CAG04995.1| unnamed protein product [Tetraodon n... 218 2e-54
gi|338409|gb|AAA60575.1| alpha-I spectrin 218 2e-54
gi|38328187|gb|AAH62163.1| Utrn protein [Mus musculus] 217 3e-54
gi|29504772|gb|AAH50183.1| Utrn protein [Mus musculus] 217 3e-54
gi|33874355|gb|AAH09242.1| DMD protein [Homo sapiens] 216 6e-54
gi|50259305|gb|EAL21978.1| hypothetical protein CNBC1180 [Crypto... 214 2e-53
gi|8569559|pdb|1DXX|A Chain A, N-Terminal Actin-Binding Domain O... 213 7e-53
gi|48143056|ref|XP_397404.1| similar to dystrophin-like protein ... 211 3e-52
gi|45384284|ref|NP_990630.1| dystrophin [Gallus gallus] >gnl|BL_... 211 3e-52
gi|17862818|gb|AAL39886.1| LP06350p [Drosophila melanogaster] 210 3e-52
gi|26348245|dbj|BAC37762.1| unnamed protein product [Mus musculus] 209 8e-52
gi|17865660|sp|O97592|DMD_CANFA Dystrophin >gnl|BL_ORD_ID|139613... 209 1e-51
gi|2511779|gb|AAC79502.1| beta III spectrin [Homo sapiens] 209 1e-51
gi|33621012|gb|AAK71387.2| Hypothetical protein M116.5 [Caenorha... 208 2e-51
gi|26340344|dbj|BAC33835.1| unnamed protein product [Mus musculus] 207 3e-51
gi|19173149|ref|NP_596952.1| similarity to NON-MUSCLE ALPHA ACTI... 207 4e-51
gi|48425543|pdb|1S35|A Chain A, Crystal Structure Of Repeats 8 A... 206 8e-51
gi|29497|emb|CAA42098.1| beta-spectrin [Homo sapiens] 205 1e-50
gi|50507815|emb|CAH04708.1| Hypothetical protein ZK1151.1d [Caen... 205 1e-50
gi|50741767|ref|XP_419629.1| PREDICTED: similar to Utrophin (Dys... 204 3e-50
gi|34304492|gb|AAQ63200.1| beta-spectrin [Canis familiaris] 203 4e-50
gi|29839561|sp|Q8NF91|SNE1_HUMAN Nesprin 1 (Nuclear envelope spe... 203 4e-50
gi|28192628|gb|AAO23669.1| spectrin-like protein [Homo sapiens] 203 5e-50
gi|383575|prf||1903296A utrophin N-terminal region 203 5e-50
gi|34849883|tpg|DAA01060.1| TPA: spectrin-like protein of the nu... 203 5e-50
gi|6730445|pdb|1QAG|A Chain A, Actin Binding Region Of The Dystr... 202 9e-50
gi|41281987|ref|NP_892006.1| nesprin 1 longest; synaptic nuclei ... 201 2e-49
gi|37725371|gb|AAO24757.1| dystrophin [Danio rerio] 201 3e-49
gi|32441707|emb|CAD67583.1| putative utrophin [Takifugu rubripes] 200 5e-49
gi|50798042|ref|XP_428326.1| PREDICTED: similar to Spectrin beta... 200 5e-49
gi|17541596|ref|NP_501432.1| calponin-like actin-binding and Gro... 199 1e-48
gi|47221248|emb|CAG13184.1| unnamed protein product [Tetraodon n... 198 1e-48
gi|23097308|ref|NP_149062.1| nesprin 1 isoform longer; synaptic ... 197 2e-48
gi|85770|pir||S01091 fodrin alpha chain (clone alpha-1) - Africa... 195 1e-47
gi|2345080|gb|AAC02790.1| beta-spectrin [Homo sapiens] 193 6e-47
gi|26333295|dbj|BAC30365.1| unnamed protein product [Mus musculus] 192 1e-46
gi|21754454|dbj|BAC04506.1| unnamed protein product [Homo sapiens] 189 8e-46
gi|24417711|gb|AAN60443.1| nesprin-2 [Homo sapiens] 189 8e-46
gi|33624848|ref|NP_055995.3| synaptic nuclei expressed gene 2 is... 189 8e-46
gi|17016967|gb|AAL33548.1| NUANCE [Homo sapiens] 189 8e-46
gi|29839588|sp|Q8WXH0|SNE2_HUMAN Nesprin 2 (Nuclear envelope spe... 189 8e-46
gi|2119257|pir||I50420 nonerythroid alpha-spectrin - chicken (fr... 188 1e-45
gi|3660036|pdb|1BKR|A Chain A, Calponin Homology (Ch) Domain Fro... 187 3e-45
gi|2914153|pdb|1AA2| Calponin Homology (Ch) Domain From Human B... 187 3e-45
gi|22597200|gb|AAN03487.1| enaptin165 short isoform [Mus musculus] 186 7e-45
gi|26336499|dbj|BAC31932.1| unnamed protein product [Mus musculus] 185 2e-44
gi|24648200|ref|NP_732427.1| CG31175-PC [Drosophila melanogaster... 184 3e-44
gi|13183552|gb|AAK15256.1| dystrophin-like protein DLP2 [Drosoph... 184 3e-44
gi|24648198|ref|NP_524405.2| CG31175-PA [Drosophila melanogaster... 184 3e-44
gi|47224613|emb|CAG03597.1| unnamed protein product [Tetraodon n... 183 6e-44
gi|29841082|gb|AAP06095.1| similar to NP_506127 alpha-actinin in... 183 6e-44
gi|2345082|gb|AAC02792.1| beta-spectrin [Homo sapiens] 182 1e-43
gi|34865470|ref|XP_216738.2| similar to nesprin-2 [Rattus norveg... 181 2e-43
gi|17016969|gb|AAL33549.1| NUANCE [Mus musculus] 181 2e-43
gi|24528464|gb|AAN62853.1| MSP-300 [Drosophila melanogaster] 180 5e-43
gi|5640028|emb|CAB51571.1| putative alpha-spectrin [Gallus gallus] 180 5e-43
gi|34577049|ref|NP_056363.2| bullous pemphigoid antigen 1 isofor... 177 2e-42
gi|28892755|ref|NP_795919.1| RIKEN cDNA 6820443O06 gene [Mus mus... 177 4e-42
gi|26351073|dbj|BAC39173.1| unnamed protein product [Mus musculus] 177 4e-42
gi|50807536|ref|XP_428917.1| PREDICTED: similar to betaIV-spectr... 176 5e-42
gi|3859891|gb|AAC72899.1| alpha-actinin [Trichomonas vaginalis] 176 7e-42
gi|18157651|gb|AAL62061.1| bullous pemphigoid antigen 1 eA [Homo... 176 9e-42
gi|27923958|sp|O94833|BPEA_HUMAN Bullous pemphigoid antigen 1, i... 175 1e-41
gi|422301|pir||S32565 actin-binding protein - slime mold (Physar... 175 2e-41
gi|4102751|gb|AAD01566.1| beta spectrin homolog [Mus musculus] 174 2e-41
gi|3551777|gb|AAC62318.1| alpha actinin [Trichomonas vaginalis] 174 3e-41
gi|47216755|emb|CAG03759.1| unnamed protein product [Tetraodon n... 173 5e-41
gi|21753085|dbj|BAC04284.1| unnamed protein product [Homo sapiens] 173 6e-41
gi|19923599|ref|NP_079010.2| calponin like transmembrane domain ... 172 8e-41
gi|7512693|pir||T17288 hypothetical protein DKFZp434P1550.1 - hu... 172 8e-41
gi|10437695|dbj|BAB15087.1| unnamed protein product [Homo sapiens] 172 8e-41
gi|46250005|gb|AAH68482.1| Calponin like transmembrane domain pr... 172 1e-40
gi|50742570|ref|XP_419679.1| PREDICTED: similar to Nesprin 1 (Nu... 171 2e-40
gi|224115|prf||1010302A spectrin alpha fragment 170 4e-40
gi|50796692|ref|XP_428221.1| PREDICTED: similar to beta4-spectri... 170 5e-40
gi|47224606|emb|CAG03590.1| unnamed protein product [Tetraodon n... 169 7e-40
gi|16716443|ref|NP_444385.1| calmin [Mus musculus] >gnl|BL_ORD_I... 168 2e-39
gi|32699547|sp|Q8C5W0|CLMN_MOUSE Calmin >gnl|BL_ORD_ID|1891163 g... 168 2e-39
gi|14278935|dbj|BAB59009.1| calmin alpha [Mus musculus] 168 2e-39
gi|14289185|dbj|BAB59120.1| calmin gamma [Mus musculus] 168 2e-39
gi|7489885|pir||T14867 interaptin - slime mold (Dictyostelium di... 167 4e-39
gi|6690782|gb|AAF24340.1| Short stop/Kakapo isoform C [Drosophil... 166 6e-39
gi|50809216|ref|XP_429009.1| PREDICTED: similar to Spectrin beta... 166 1e-38
gi|2239268|gb|AAB62275.1| cortexillin I [Dictyostelium discoideum] 162 8e-38
gi|14719556|pdb|1HCI|A Chain A, Crystal Structure Of The Rod Dom... 162 1e-37
gi|338334|gb|AAA60572.1| erythrocyte beta-spectrin 162 1e-37
gi|48101374|ref|XP_395113.1| similar to CG18076-PH [Apis mellifera] 161 2e-37
gi|11137614|emb|CAC15920.1| dJ562N20.1.1 (trabeculin alpha (acti... 161 2e-37
gi|33188443|ref|NP_149033.2| microfilament and actin filament cr... 161 2e-37
gi|30316105|sp|Q96PK2|MAC4_HUMAN Microtubule-actin crosslinking ... 160 5e-37
gi|33874637|gb|AAH15620.2| ACTN4 protein [Homo sapiens] 158 2e-36
gi|27503168|gb|AAH42134.1| SYNE2 protein [Homo sapiens] >gnl|BL_... 158 2e-36
gi|47215103|emb|CAF98177.1| unnamed protein product [Tetraodon n... 158 2e-36
gi|34874618|ref|XP_237042.2| similar to bullous pemphigoid antig... 158 2e-36
gi|31202361|ref|XP_310129.1| ENSANGP00000019967 [Anopheles gambi... 157 4e-36
gi|48095516|ref|XP_392311.1| similar to Short stop/Kakapo long i... 156 6e-36
gi|17016965|gb|AAL33547.1| NUANCE-N-33 [Homo sapiens] 156 8e-36
gi|38090354|ref|XP_358299.1| synaptic nuclear envelope 1 [Mus mu... 155 1e-35
gi|2239266|gb|AAB62274.1| cortexillin II [Dictyostelium discoide... 155 2e-35
gi|109842|pir||A43769 fodrin alpha chain - mouse (fragment) 154 4e-35
gi|930145|emb|CAA31289.1| alpha-fodrin (382 AA) [Mus musculus] 154 4e-35
gi|5107216|gb|AAD40020.1| cortexillin I [Polysphondylium pallidum] 153 5e-35
gi|24581873|ref|NP_524924.2| CG18251-PB [Drosophila melanogaster... 151 2e-34
gi|29893185|gb|AAP03079.1| antigen [Taenia cellulosae] 151 2e-34
gi|88622|pir||B27671 spectrin alpha chain, nonerythroid - human ... 150 4e-34
gi|34328014|dbj|BAA32310.3| KIAA0465 protein [Homo sapiens] 149 7e-34
gi|189071|gb|AAA59904.1| alpha-spectrin 149 1e-33
gi|50759862|ref|XP_417817.1| PREDICTED: similar to microfilament... 147 3e-33
gi|5032285|ref|NP_003998.1| dystrophin Dp427l isoform; dystrophi... 147 4e-33
gi|47228910|emb|CAG09425.1| unnamed protein product [Tetraodon n... 147 5e-33
gi|47208842|emb|CAF94383.1| unnamed protein product [Tetraodon n... 147 5e-33
gi|92757|pir||A27671 spectrin alpha chain, nonerythroid - rat (f... 146 8e-33
gi|5107218|gb|AAD40021.1| cortexillin II [Polysphondylium pallidum] 145 1e-32
gi|47214147|emb|CAG07924.1| unnamed protein product [Tetraodon n... 145 1e-32
gi|17426164|gb|AAL39000.1| macrophin 1 isoform 2 [Homo sapiens] 145 2e-32
gi|17426161|gb|AAL38997.1| macrophin 1 isoform 4 [Homo sapiens] 145 2e-32
gi|7511874|pir||T13734 groovin gene protein - fruit fly (Drosoph... 144 2e-32
gi|50744842|ref|XP_419901.1| PREDICTED: similar to Bullous pemph... 144 2e-32
gi|48120804|ref|XP_393229.1| similar to CG18251-PB [Apis mellifera] 144 2e-32
gi|34534467|dbj|BAC87016.1| unnamed protein product [Homo sapiens] 143 7e-32
gi|121115|sp|P13466|GELA_DICDI Gelation factor (Actin binding pr... 142 1e-31
gi|38083712|ref|XP_284175.2| RIKEN cDNA 1110055E19 [Mus musculus] 141 2e-31
gi|34867695|ref|XP_234500.2| similar to calmin alpha [Rattus nor... 141 2e-31
gi|38084042|ref|XP_355766.1| similar to gamma-filamin [Mus muscu... 141 2e-31
gi|38086441|ref|XP_356341.1| similar to dystrophin major muscle ... 140 6e-31
gi|8885790|gb|AAF80245.1| filamin 2 [Homo sapiens] 140 6e-31
gi|7677526|gb|AAF67190.1| gamma-filamin [Homo sapiens] 140 6e-31
gi|4557597|ref|NP_001449.1| gamma filamin; filamin 2; filamin C,... 139 7e-31
gi|32129530|sp|Q14315|FLNC_HUMAN Filamin C (Gamma-filamin) (Fila... 139 7e-31
gi|34870961|ref|XP_342907.1| similar to macrophin 1 isoform 4 [R... 137 3e-30
gi|7513587|pir||T30849 actin binding protein ACF7, neural isofor... 136 6e-30
gi|12847774|dbj|BAB27703.1| unnamed protein product [Mus musculus] 135 1e-29
gi|45383035|ref|NP_989905.1| filamin [Gallus gallus] >gnl|BL_ORD... 135 1e-29
gi|31227672|ref|XP_317924.1| ENSANGP00000011363 [Anopheles gambi... 134 2e-29
gi|5419655|emb|CAB46442.1| filamin, muscle isoform [Homo sapiens] 134 3e-29
gi|39985523|gb|AAR36862.1| filamin [Hirudo medicinalis] 134 4e-29
gi|1695889|gb|AAB40944.1| EhABP [Entamoeba histolytica] 133 7e-29
gi|47224453|emb|CAG08703.1| unnamed protein product [Tetraodon n... 132 9e-29
gi|26354418|dbj|BAC40837.1| unnamed protein product [Mus musculus] 132 1e-28
gi|1203969|gb|AAA92644.1| filamin [Homo sapiens] 132 1e-28
gi|38086405|ref|XP_207130.3| filamin, alpha [Mus musculus] 132 1e-28
gi|38087063|ref|XP_289920.2| similar to filamin [Mus musculus] >... 132 1e-28
gi|4503745|ref|NP_001447.1| filamin 1 (actin-binding protein-280... 132 1e-28
gi|34881882|ref|XP_238167.2| similar to FLJ00343 protein [Rattus... 132 1e-28
gi|21748542|dbj|BAC03408.1| FLJ00343 protein [Homo sapiens] 132 1e-28
gi|20521141|dbj|BAA34448.2| KIAA0728 protein [Homo sapiens] 132 2e-28
gi|34869526|ref|XP_224561.2| similar to actin-binding protein ho... 130 4e-28
gi|6716516|gb|AAF26672.1| nonerythroid alpha-spectrin [Homo sapi... 130 4e-28
gi|38257404|sp|Q80X90|FLNB_MOUSE Filamin B (FLN-B) (Beta-filamin... 130 4e-28
gi|38075551|ref|XP_127565.4| filamin B, beta [Mus musculus] 130 4e-28
gi|3282771|gb|AAC33845.1| actin-binding protein homolog ABP-278 ... 130 6e-28
gi|4503747|ref|NP_001448.1| filamin B, beta (actin binding prote... 130 6e-28
gi|4514645|dbj|BAA75471.1| cgABP260 actin-binding domain [Gallus... 129 1e-27
gi|45383033|ref|NP_989904.1| cgABP260 [Gallus gallus] >gnl|BL_OR... 129 1e-27
gi|28723|emb|CAA38970.1| alpha-actinin [Homo sapiens] 127 4e-27
gi|45549223|ref|NP_524383.2| CG3937-PA [Drosophila melanogaster]... 127 5e-27
gi|6707288|gb|AAF25614.1| filamin1 [Drosophila melanogaster] 127 5e-27
gi|45553391|ref|NP_996224.1| CG3937-PD [Drosophila melanogaster]... 127 5e-27
gi|1079404|pir||A49551 filamin, Muller cell - chicken >gnl|BL_OR... 126 6e-27
gi|91302|pir||A05283 spectrin alpha chain - mouse (fragment) >gn... 126 8e-27
gi|553648|gb|AAA60569.1| erythrocyte alpha-spectrin 125 1e-26
gi|34855625|ref|XP_346542.1| hypothetical protein XP_346541 [Rat... 124 2e-26
gi|17543920|ref|NP_499912.1| filamin (118.6 kD) (4B124) [Caenorh... 124 2e-26
gi|6118392|gb|AAF04108.1| filamin A [Drosophila melanogaster] 124 2e-26
gi|12002996|gb|AAG43431.1| filamin isoform A [Drosophila melanog... 124 2e-26
gi|27227735|emb|CAD59068.1| alpha-actinin [Salmo salar] 124 4e-26
gi|30314556|dbj|BAC76052.1| retina filamin [Gallus gallus] 124 4e-26
gi|224116|prf||1010302B spectrin beta fragment 121 2e-25
gi|21756268|dbj|BAC04848.1| unnamed protein product [Homo sapiens] 121 2e-25
gi|50748800|ref|XP_421410.1| PREDICTED: similar to NUANCE [Gallu... 121 3e-25
gi|39580924|emb|CAE65554.1| Hypothetical protein CBG10542 [Caeno... 121 3e-25
gi|7512993|pir||T00079 hypothetical protein KIAA0465 - human (fr... 121 3e-25
gi|50768125|ref|XP_426985.1| PREDICTED: similar to erythroid spe... 120 4e-25
gi|2501851|gb|AAC02793.1| beta-spectrin [Homo sapiens] 119 8e-25
gi|28839555|gb|AAH47798.1| Zgc:55983 protein [Danio rerio] 117 3e-24
gi|30407952|gb|AAP30027.1| cardiomyocyte alpha-spectrin [Canis f... 117 4e-24
gi|39596188|emb|CAE69825.1| Hypothetical protein CBG16146 [Caeno... 117 5e-24
gi|627059|pir||A45592 liver stage antigen LSA-1 - malaria parasi... 115 1e-23
gi|17550566|ref|NP_509579.1| filamin (XK23) [Caenorhabditis eleg... 114 3e-23
gi|31209293|ref|XP_313613.1| ENSANGP00000003616 [Anopheles gambi... 114 3e-23
gi|26345844|dbj|BAC36573.1| unnamed protein product [Mus musculus] 113 6e-23
gi|48101343|ref|XP_395105.1| similar to ENSANGP00000017034 [Apis... 113 7e-23
gi|47218915|emb|CAF98113.1| unnamed protein product [Tetraodon n... 112 1e-22
gi|48116937|ref|XP_396410.1| similar to CG11259-PA [Apis mellifera] 110 6e-22
gi|47220085|emb|CAG12233.1| unnamed protein product [Tetraodon n... 109 8e-22
gi|37360066|dbj|BAC98011.1| mKIAA0728 protein [Mus musculus] 108 1e-21
gi|13096618|pdb|1G8X|A Chain A, Structure Of A Genetically Engin... 108 2e-21
gi|49115489|gb|AAH73402.1| Unknown (protein for MGC:80860) [Xeno... 108 2e-21
gi|34871286|ref|XP_221956.2| similar to FLJ23471 protein [Rattus... 107 4e-21
gi|47211990|emb|CAF95266.1| unnamed protein product [Tetraodon n... 107 5e-21
gi|31324577|ref|NP_203744.1| molecule interacting with Rab13; MI... 106 9e-21
gi|6572155|emb|CAB62979.1| dJ1014D13.2 (novel protein similar to... 106 9e-21
gi|31044222|tpg|DAA01346.1| TPA: MICAL-like 2 [Homo sapiens] 105 1e-20
gi|32189724|ref|NP_859454.1| hypothetical protein Chr3_0210 [Lei... 105 1e-20
gi|33667117|ref|NP_891554.1| MICAL-like 2 isoform 1 [Homo sapien... 105 1e-20
gi|31208417|ref|XP_313175.1| ENSANGP00000013969 [Anopheles gambi... 105 1e-20
gi|18676484|dbj|BAB84894.1| FLJ00139 protein [Homo sapiens] 105 1e-20
gi|50728756|ref|XP_416269.1| PREDICTED: similar to mKIAA1668 pro... 104 3e-20
gi|38077847|ref|XP_354923.1| DNA Segment, Chr 15 Massachusetts I... 104 3e-20
gi|37360502|dbj|BAC98229.1| mKIAA1668 protein [Mus musculus] 104 3e-20
gi|34866936|ref|XP_343289.1| similar to CG11259-PA [Rattus norve... 104 3e-20
gi|6137376|pdb|1CUN|A Chain A, Crystal Structure Of Repeats 16 A... 104 3e-20
gi|46397868|sp|Q8BGT6|MI13_MOUSE Molecule interacting with Rab13... 104 3e-20
gi|42415519|ref|NP_963879.1| zgc:55358; wu:fd16d06; ORFNames=wu:... 104 3e-20
gi|47211761|emb|CAG12329.1| unnamed protein product [Tetraodon n... 103 4e-20
gi|2511781|gb|AAC79503.1| beta III spectrin [Homo sapiens] 103 4e-20
gi|47228911|emb|CAG09426.1| unnamed protein product [Tetraodon n... 103 4e-20
gi|4389302|pdb|1BHD|A Chain A, Second Calponin Homology Domain F... 103 4e-20
gi|39594084|emb|CAE70194.1| Hypothetical protein CBG16668 [Caeno... 103 4e-20
>gi|17562506|ref|NP_504748.1| beta-G spectrin, UNCoordinated
locomotion UNC-70 (262.2 kD) (unc-70) [Caenorhabditis
elegans]
gi|5734148|gb|AAD49859.1| beta-G spectrin [Caenorhabditis elegans]
gi|8118453|gb|AAF72996.1| beta-spectrin [Caenorhabditis elegans]
gi|15011760|gb|AAK77611.1| Uncoordinated protein 70, isoform a
[Caenorhabditis elegans]
Length = 2257
Score = 4323 bits (11213), Expect = 0.0
Identities = 2181/2245 (97%), Positives = 2181/2245 (97%)
Frame = +1
Query: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 180
MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK
Sbjct: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 60
Query: 181 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 360
VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG
Sbjct: 61 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 120
Query: 361 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 540
SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN
Sbjct: 121 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 180
Query: 541 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 720
VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE
Sbjct: 181 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 240
Query: 721 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 900
DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL
Sbjct: 241 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 300
Query: 901 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 1080
LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR
Sbjct: 301 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 360
Query: 1081 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 1260
ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR
Sbjct: 361 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 420
Query: 1261 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYH 1440
ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEER NYH
Sbjct: 421 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYH 480
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
DQAKINERKENV ARRVRLELSMAIQKIFH IKSRLLSE
Sbjct: 481 DQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSE 540
Query: 1621 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 1800
DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID
Sbjct: 541 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 600
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI
Sbjct: 601 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 660
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK
Sbjct: 661 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 720
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH
Sbjct: 721 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 780
Query: 2341 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 2520
DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS
Sbjct: 781 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 840
Query: 2521 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 2700
LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND
Sbjct: 841 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 900
Query: 2701 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 2880
LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW
Sbjct: 901 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 960
Query: 2881 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 3060
IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA
Sbjct: 961 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 1020
Query: 3061 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 3240
QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE
Sbjct: 1021 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 1080
Query: 3241 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 3420
PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG
Sbjct: 1081 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 1140
Query: 3421 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 3600
WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR
Sbjct: 1141 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 1200
Query: 3601 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 3780
HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK
Sbjct: 1201 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 1260
Query: 3781 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 3960
LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL
Sbjct: 1261 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 1320
Query: 3961 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA
Sbjct: 1321 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 1380
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID H
Sbjct: 1381 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELH 1440
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK
Sbjct: 1441 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 1500
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL
Sbjct: 1501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 1560
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ
Sbjct: 1561 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 1620
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQD
Sbjct: 1621 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKER 1680
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI
Sbjct: 1681 RKRLEETLELYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 1740
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF
Sbjct: 1741 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 1800
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL
Sbjct: 1801 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 1860
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV
Sbjct: 1861 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 1920
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK
Sbjct: 1921 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 1980
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE
Sbjct: 1981 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 2040
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 6300
ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST
Sbjct: 2041 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 2100
Query: 6301 PAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDP 6480
PAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDP
Sbjct: 2101 PAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDP 2160
Query: 6481 KHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL 6660
KHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL
Sbjct: 2161 KHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL 2220
Query: 6661 QVATGQAQLEEASRSQTLPAEGSAT 6735
QVATGQAQLEEASRSQTLPAEGSAT
Sbjct: 2221 QVATGQAQLEEASRSQTLPAEGSAT 2245
>gi|17976528|gb|AAK77612.2| Uncoordinated protein 70, isoform b
[Caenorhabditis elegans]
Length = 2302
Score = 4302 bits (11157), Expect = 0.0
Identities = 2181/2290 (95%), Positives = 2181/2290 (95%), Gaps = 45/2290 (1%)
Frame = +1
Query: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 180
MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK
Sbjct: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 60
Query: 181 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 360
VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG
Sbjct: 61 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 120
Query: 361 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 540
SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN
Sbjct: 121 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 180
Query: 541 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 720
VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE
Sbjct: 181 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 240
Query: 721 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 900
DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL
Sbjct: 241 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 300
Query: 901 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 1080
LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR
Sbjct: 301 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 360
Query: 1081 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 1260
ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR
Sbjct: 361 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 420
Query: 1261 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYH 1440
ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEER NYH
Sbjct: 421 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYH 480
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
DQAKINERKENV ARRVRLELSMAIQKIFH IKSRLLSE
Sbjct: 481 DQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSE 540
Query: 1621 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 1800
DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID
Sbjct: 541 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 600
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI
Sbjct: 601 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 660
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK
Sbjct: 661 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 720
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH
Sbjct: 721 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 780
Query: 2341 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 2520
DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS
Sbjct: 781 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 840
Query: 2521 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 2700
LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND
Sbjct: 841 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 900
Query: 2701 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 2880
LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW
Sbjct: 901 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 960
Query: 2881 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 3060
IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA
Sbjct: 961 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 1020
Query: 3061 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 3240
QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE
Sbjct: 1021 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 1080
Query: 3241 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 3420
PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG
Sbjct: 1081 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 1140
Query: 3421 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 3600
WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR
Sbjct: 1141 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 1200
Query: 3601 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 3780
HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK
Sbjct: 1201 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 1260
Query: 3781 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 3960
LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL
Sbjct: 1261 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 1320
Query: 3961 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA
Sbjct: 1321 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 1380
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID H
Sbjct: 1381 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELH 1440
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK
Sbjct: 1441 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 1500
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL
Sbjct: 1501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 1560
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ
Sbjct: 1561 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 1620
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQD
Sbjct: 1621 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKER 1680
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI
Sbjct: 1681 RKRLEETLELYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 1740
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF
Sbjct: 1741 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 1800
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL
Sbjct: 1801 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 1860
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV
Sbjct: 1861 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 1920
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK
Sbjct: 1921 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 1980
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE
Sbjct: 1981 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 2040
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 6300
ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST
Sbjct: 2041 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 2100
Query: 6301 PAAETSFGAQDD---------------------------------------------GAK 6345
PAAETSFGAQDD GAK
Sbjct: 2101 PAAETSFGAQDDDADITHSSLEGHRKSSHEKRLAHSESSSWRKSLARAAKFDSKDPKGAK 2160
Query: 6346 QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMAL 6525
QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMAL
Sbjct: 2161 QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMAL 2220
Query: 6526 PGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRS 6705
PGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRS
Sbjct: 2221 PGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRS 2280
Query: 6706 QTLPAEGSAT 6735
QTLPAEGSAT
Sbjct: 2281 QTLPAEGSAT 2290
>gi|5734146|gb|AAD49858.1| beta-G spectrin [Caenorhabditis elegans]
Length = 2302
Score = 4302 bits (11157), Expect = 0.0
Identities = 2181/2290 (95%), Positives = 2181/2290 (95%), Gaps = 45/2290 (1%)
Frame = +1
Query: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 180
MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK
Sbjct: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 60
Query: 181 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 360
VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG
Sbjct: 61 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 120
Query: 361 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 540
SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN
Sbjct: 121 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 180
Query: 541 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 720
VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE
Sbjct: 181 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 240
Query: 721 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 900
DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL
Sbjct: 241 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 300
Query: 901 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 1080
LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR
Sbjct: 301 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 360
Query: 1081 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 1260
ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR
Sbjct: 361 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 420
Query: 1261 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYH 1440
ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEER NYH
Sbjct: 421 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYH 480
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
DQAKINERKENV ARRVRLELSMAIQKIFH IKSRLLSE
Sbjct: 481 DQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSE 540
Query: 1621 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 1800
DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID
Sbjct: 541 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 600
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI
Sbjct: 601 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 660
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK
Sbjct: 661 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 720
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH
Sbjct: 721 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 780
Query: 2341 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 2520
DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS
Sbjct: 781 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 840
Query: 2521 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 2700
LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND
Sbjct: 841 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 900
Query: 2701 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 2880
LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW
Sbjct: 901 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 960
Query: 2881 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 3060
IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA
Sbjct: 961 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 1020
Query: 3061 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 3240
QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE
Sbjct: 1021 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 1080
Query: 3241 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 3420
PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG
Sbjct: 1081 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 1140
Query: 3421 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 3600
WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR
Sbjct: 1141 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 1200
Query: 3601 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 3780
HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK
Sbjct: 1201 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 1260
Query: 3781 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 3960
LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL
Sbjct: 1261 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 1320
Query: 3961 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA
Sbjct: 1321 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 1380
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID H
Sbjct: 1381 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELH 1440
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK
Sbjct: 1441 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 1500
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL
Sbjct: 1501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 1560
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ
Sbjct: 1561 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 1620
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQD
Sbjct: 1621 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKER 1680
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI
Sbjct: 1681 RKRLEETLELYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 1740
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF
Sbjct: 1741 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 1800
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL
Sbjct: 1801 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 1860
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV
Sbjct: 1861 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 1920
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK
Sbjct: 1921 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 1980
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE
Sbjct: 1981 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 2040
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 6300
ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST
Sbjct: 2041 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 2100
Query: 6301 PAAETSFGAQDD---------------------------------------------GAK 6345
PAAETSFGAQDD GAK
Sbjct: 2101 PAAETSFGAQDDDADITHSSLEGHRKSSHEKRLAHSESSSWRKSLARAPKFDSKDPKGAK 2160
Query: 6346 QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMAL 6525
QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMAL
Sbjct: 2161 QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMAL 2220
Query: 6526 PGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRS 6705
PGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRS
Sbjct: 2221 PGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRS 2280
Query: 6706 QTLPAEGSAT 6735
QTLPAEGSAT
Sbjct: 2281 QTLPAEGSAT 2290
>gi|7505762|pir||T29140 hypothetical protein K11C4.3 - Caenorhabditis
elegans
Length = 2326
Score = 4259 bits (11047), Expect = 0.0
Identities = 2148/2216 (96%), Positives = 2149/2216 (96%)
Frame = +1
Query: 88 RIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKP 267
R + L DERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKP
Sbjct: 99 RFRGLRDERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKP 158
Query: 268 TPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDIT 447
TPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDIT
Sbjct: 159 TPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDIT 218
Query: 448 FEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYD 627
FEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYD
Sbjct: 219 FEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYD 278
Query: 628 NLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQD 807
NLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQD
Sbjct: 279 NLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQD 338
Query: 808 NIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTE 987
NIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTE
Sbjct: 339 NIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTE 398
Query: 988 FNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAE 1167
FNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAE
Sbjct: 399 FNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAE 458
Query: 1168 HERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKK 1347
HERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKK
Sbjct: 459 HERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKK 518
Query: 1348 HEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVR 1527
HEAIETDIFAYEER NYHDQAKINERKENV ARRVR
Sbjct: 519 HEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVR 578
Query: 1528 LELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGER 1707
LELSMAIQKIFH IKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGER
Sbjct: 579 LELSMAIQKIFHDMLLTLDLMDDIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGER 638
Query: 1708 VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKR 1887
VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKR
Sbjct: 639 VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKR 698
Query: 1888 LCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDV 2067
LCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDV
Sbjct: 699 LCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDV 758
Query: 2068 SGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRY 2247
SGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRY
Sbjct: 759 SGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRY 818
Query: 2248 LYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPD 2427
LYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPD
Sbjct: 819 LYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPD 878
Query: 2428 IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGR 2607
IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGR
Sbjct: 879 IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGR 938
Query: 2608 DIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQ 2787
DIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQ
Sbjct: 939 DIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQ 998
Query: 2788 LRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLS 2967
LRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLS
Sbjct: 999 LRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLS 1058
Query: 2968 MMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLD 3147
MMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLD
Sbjct: 1059 MMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLD 1118
Query: 3148 EAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYK 3327
EAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYK
Sbjct: 1119 EAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYK 1178
Query: 3328 KMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAK 3507
KMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAK
Sbjct: 1179 KMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAK 1238
Query: 3508 QAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDG 3687
QAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDG
Sbjct: 1239 QAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDG 1298
Query: 3688 HYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQ 3867
HYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQ
Sbjct: 1299 HYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQ 1358
Query: 3868 DETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELA 4047
DETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELA
Sbjct: 1359 DETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELA 1418
Query: 4048 TQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAM 4227
TQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAM
Sbjct: 1419 TQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAM 1478
Query: 4228 QKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRR 4407
QKQHLIETEMIKKAQHID HPDELENIKAHRLAVQEQLQRLQAPLDDRR
Sbjct: 1479 QKQHLIETEMIKKAQHIDQLMEMEPQLEELHPDELENIKAHRLAVQEQLQRLQAPLDDRR 1538
Query: 4408 KALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHE 4587
KALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHE
Sbjct: 1539 KALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHE 1598
Query: 4588 PWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLY 4767
PWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLY
Sbjct: 1599 PWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLY 1658
Query: 4768 DCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFV 4947
DCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFV
Sbjct: 1659 DCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFV 1718
Query: 4948 EEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEV 5127
EEKSPLTEQIQVRQAQIEKLYAGLQD YALHREIDDLLQWIADKEV
Sbjct: 1719 EEKSPLTEQIQVRQAQIEKLYAGLQDLSKERRKRLEETLELYALHREIDDLLQWIADKEV 1778
Query: 5128 VAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALW 5307
VAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALW
Sbjct: 1779 VAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALW 1838
Query: 5308 KDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSV 5487
KDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSV
Sbjct: 1839 KDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSV 1898
Query: 5488 GALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGL 5667
GALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGL
Sbjct: 1899 GALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGL 1958
Query: 5668 CDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAE 5847
CDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAE
Sbjct: 1959 CDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAE 2018
Query: 5848 IDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEV 6027
IDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEV
Sbjct: 2019 IDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEV 2078
Query: 6028 YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 6207
YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL
Sbjct: 2079 YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 2138
Query: 6208 TTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHT 6387
TTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHT
Sbjct: 2139 TTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHT 2198
Query: 6388 YESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKK 6567
YESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKK
Sbjct: 2199 YESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKK 2258
Query: 6568 KNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPAEGSAT 6735
KNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPAEGSAT
Sbjct: 2259 KNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPAEGSAT 2314
>gi|39594389|emb|CAE71967.1| Hypothetical protein CBG19038
[Caenorhabditis briggsae]
Length = 2299
Score = 4217 bits (10938), Expect = 0.0
Identities = 2130/2287 (93%), Positives = 2161/2287 (94%), Gaps = 45/2287 (1%)
Frame = +1
Query: 10 VDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQD 189
VD NSGAY Q+EDYDDNSSARLFERSRI+ALA+ERELVQKKTFTKWVNSHLVRVSCKVQD
Sbjct: 1 VDVNSGAYNQEEDYDDNSSARLFERSRIQALANERELVQKKTFTKWVNSHLVRVSCKVQD 60
Query: 190 LYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHD 369
LYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHD
Sbjct: 61 LYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHD 120
Query: 370 IVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKN 549
IVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKN
Sbjct: 121 IVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKN 180
Query: 550 FSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVN 729
FSTSWRDGLAFNALIHKHR DLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVN
Sbjct: 181 FSTSWRDGLAFNALIHKHRSDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVN 240
Query: 730 VDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEW 909
VDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLL+W
Sbjct: 241 VDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLDW 300
Query: 910 INAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANN 1089
I+AKIQLLN+RHFENNLEGVQ+QLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANN
Sbjct: 301 IHAKIQLLNDRHFENNLEGVQKQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANN 360
Query: 1090 QRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETW 1269
QRPFVPREGKLIADINRAWQSLEKAEHEREL LKEELIRQEKLEQLAARFNRKAEMRETW
Sbjct: 361 QRPFVPREGKLIADINRAWQSLEKAEHERELALKEELIRQEKLEQLAARFNRKAEMRETW 420
Query: 1270 LTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQA 1449
LTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEER NYHDQA
Sbjct: 421 LTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQA 480
Query: 1450 KINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLG 1629
KINERKENV ARRVRLELSMAIQKIFH I+SRLLSEDLG
Sbjct: 481 KINERKENVLKLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIRSRLLSEDLG 540
Query: 1630 AHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERS 1809
AHLMDVEDLLQKHALLESDINIIGERVNNSIAQ+QRFRN DGPDGSGYKPVEPGTIDER
Sbjct: 541 AHLMDVEDLLQKHALLESDINIIGERVNNSIAQSQRFRNEDGPDGSGYKPVEPGTIDERC 600
Query: 1810 DVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTV 1989
D LQ++YKELL+LAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTV
Sbjct: 601 DTLQQKYKELLELAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTV 660
Query: 1990 SHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELS 2169
SHLLAKHKNAENNLRDLEKYLDRLDVSG+ELQDE+IPGSDNIPPRLAEIRDYINKLKELS
Sbjct: 661 SHLLAKHKNAENNLRDLEKYLDRLDVSGRELQDENIPGSDNIPPRLAEIRDYINKLKELS 720
Query: 2170 ASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDEL 2349
A+RKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDV DEL
Sbjct: 721 AARKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVTDEL 780
Query: 2350 QNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYK 2529
QNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTL+QKAELENL+QLRKQRLIDALSLYK
Sbjct: 781 QNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLRQKAELENLAQLRKQRLIDALSLYK 840
Query: 2530 LYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLAR 2709
LYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKV NVNDLAR
Sbjct: 841 LYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVANVNDLAR 900
Query: 2710 QLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIED 2889
QLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIED
Sbjct: 901 QLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIED 960
Query: 2890 KTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAI 3069
KTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAI
Sbjct: 961 KTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAI 1020
Query: 3070 REDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQS 3249
REDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQS
Sbjct: 1021 REDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQS 1080
Query: 3250 LAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEE 3429
LAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEE
Sbjct: 1081 LAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEE 1140
Query: 3430 LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQD 3609
LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDD+PQSLEQAENQLKRHQD
Sbjct: 1141 LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDVPQSLEQAENQLKRHQD 1200
Query: 3610 FITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKD 3789
FITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKD
Sbjct: 1201 FITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKD 1260
Query: 3790 ALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL 3969
ALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL
Sbjct: 1261 ALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL 1320
Query: 3970 KHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK 4149
KHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK
Sbjct: 1321 KHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK 1380
Query: 4150 EWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDE 4329
EWATQLENEMTREDQP DLTTVNVAMQKQHLIETEMIKKAQHID HP+E
Sbjct: 1381 EWATQLENEMTREDQPADLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELHPEE 1440
Query: 4330 LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQN 4509
LENI+AHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLA+AQN
Sbjct: 1441 LENIRAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLARAQN 1500
Query: 4510 LGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSA 4689
LGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELR+A
Sbjct: 1501 LGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRAA 1560
Query: 4690 WQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKK 4869
WQELK+AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKK
Sbjct: 1561 WQELKDAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKK 1620
Query: 4870 HERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXX 5049
HERLQSDIDKFADTIRALATKAHKFVEEKSPL+EQI VRQAQIEKLYAGLQD
Sbjct: 1621 HERLQSDIDKFADTIRALATKAHKFVEEKSPLSEQITVRQAQIEKLYAGLQDLSKERRKR 1680
Query: 5050 XXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSE 5229
YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSE
Sbjct: 1681 LEETLELYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSE 1740
Query: 5230 RVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHD 5409
RVANANDGCD+LI HGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHD
Sbjct: 1741 RVANANDGCDSLIAHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHD 1800
Query: 5410 CRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDG 5589
CRDCLSRIMEKTHAMP+DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDG
Sbjct: 1801 CRDCLSRIMEKTHAMPEDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDG 1860
Query: 5590 YAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKRE 5769
YAGDKALDIGSRESEVVKAWRHLRGLCDARTSRL+DTSDLFKFMNMVRDLLLWMDEVKRE
Sbjct: 1861 YAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLVDTSDLFKFMNMVRDLLLWMDEVKRE 1920
Query: 5770 MNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLI 5949
MNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLI
Sbjct: 1921 MNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLI 1980
Query: 5950 KLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETI 6129
KLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLIS+EYGRNLEETI
Sbjct: 1981 KLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISREYGRNLEETI 2040
Query: 6130 KLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRSTPAA 6309
KLIKKHEAFEKSA AQEERFLALEKLTTFELKE QHREEET KRRGPAHIGSPSRSTPAA
Sbjct: 2041 KLIKKHEAFEKSALAQEERFLALEKLTTFELKENQHREEETQKRRGPAHIGSPSRSTPAA 2100
Query: 6310 ETSFGAQDD---------------------------------------------GAKQGE 6354
ETSFGAQDD GAKQGE
Sbjct: 2101 ETSFGAQDDDADITHSSLESHRKTSHEKRLAHSESSSWRKSLARAPKFDNKDPKGAKQGE 2160
Query: 6355 AFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGC 6534
AFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNEL+FYKDPKHRDESVHGEPPMALPGC
Sbjct: 2161 AFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELAFYKDPKHRDESVHGEPPMALPGC 2220
Query: 6535 SVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTL 6714
SVNVASDYQKKKNVLSLRLP+GAEYL QCGSEEDMQRWLTELQVATGQAQLEEASRSQTL
Sbjct: 2221 SVNVASDYQKKKNVLSLRLPVGAEYLLQCGSEEDMQRWLTELQVATGQAQLEEASRSQTL 2280
Query: 6715 PAEGSAT 6735
P +GSAT
Sbjct: 2281 PEQGSAT 2287
>gi|25154697|ref|NP_504749.2| beta-G spectrin, UNCoordinated
locomotion UNC-70 (260.7 kD) (unc-70) [Caenorhabditis
elegans]
Length = 2239
Score = 4065 bits (10543), Expect = 0.0
Identities = 2062/2169 (95%), Positives = 2071/2169 (95%), Gaps = 4/2169 (0%)
Frame = +1
Query: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 180
MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK
Sbjct: 1 MATVDGNSGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCK 60
Query: 181 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 360
VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG
Sbjct: 61 VQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLG 120
Query: 361 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 540
SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN
Sbjct: 121 SHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVN 180
Query: 541 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 720
VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE
Sbjct: 181 VKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAE 240
Query: 721 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 900
DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL
Sbjct: 241 DVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDL 300
Query: 901 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 1080
LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR
Sbjct: 301 LEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMR 360
Query: 1081 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 1260
ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR
Sbjct: 361 ANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMR 420
Query: 1261 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYH 1440
ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEER NYH
Sbjct: 421 ETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYH 480
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
DQAKINERKENV ARRVRLELSMAIQKIFH IKSRLLSE
Sbjct: 481 DQAKINERKENVLQLWNYLFQLLLARRVRLELSMAIQKIFHDMLLTLDLMDDIKSRLLSE 540
Query: 1621 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 1800
DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID
Sbjct: 541 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 600
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI
Sbjct: 601 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 660
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK
Sbjct: 661 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 720
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH
Sbjct: 721 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 780
Query: 2341 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 2520
DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS
Sbjct: 781 DELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALS 840
Query: 2521 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 2700
LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND
Sbjct: 841 LYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVND 900
Query: 2701 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 2880
LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW
Sbjct: 901 LARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTW 960
Query: 2881 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 3060
IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA
Sbjct: 961 IEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEA 1020
Query: 3061 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 3240
QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE
Sbjct: 1021 QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEE 1080
Query: 3241 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 3420
PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG
Sbjct: 1081 PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 1140
Query: 3421 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 3600
WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR
Sbjct: 1141 WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKR 1200
Query: 3601 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 3780
HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK
Sbjct: 1201 HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK 1260
Query: 3781 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 3960
LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL
Sbjct: 1261 LKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL 1320
Query: 3961 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA
Sbjct: 1321 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 1380
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID H
Sbjct: 1381 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDQLMEMEPQLEELH 1440
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK
Sbjct: 1441 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 1500
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL
Sbjct: 1501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 1560
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ
Sbjct: 1561 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 1620
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQD
Sbjct: 1621 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDLSKER 1680
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI
Sbjct: 1681 RKRLEETLELYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 1740
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF
Sbjct: 1741 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 1800
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL
Sbjct: 1801 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 1860
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV
Sbjct: 1861 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 1920
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK
Sbjct: 1921 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 1980
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE
Sbjct: 1981 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 2040
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 6300
ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST
Sbjct: 2041 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRST 2100
Query: 6301 PAAETSFGAQDDGAK-QGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKD 6477
PAAETSFGAQDD A + EG RK ++E + + SW K A + + ++
Sbjct: 2101 PAAETSFGAQDDDADITHSSLEGH--RKSSHEKRLAHSESSSWRKSLARAQSSTARIQRE 2158
Query: 6478 P---KHRDE 6495
P KH E
Sbjct: 2159 PNKEKHSKE 2167
Score = 181 bits (458), Expect = 3e-43
Identities = 82/82 (100%), Positives = 82/82 (100%)
Frame = +2
Query: 6338 EPNKEKHSKERLSESTLTRVSTGKRLTAHGRNFTQCCGRMNCHSTKIRSIEMNLCMESHQ 6517
EPNKEKHSKERLSESTLTRVSTGKRLTAHGRNFTQCCGRMNCHSTKIRSIEMNLCMESHQ
Sbjct: 2158 EPNKEKHSKERLSESTLTRVSTGKRLTAHGRNFTQCCGRMNCHSTKIRSIEMNLCMESHQ 2217
Query: 6518 WHCQDALSTWHQTIKRRRTYCR 6583
WHCQDALSTWHQTIKRRRTYCR
Sbjct: 2218 WHCQDALSTWHQTIKRRRTYCR 2239
>gi|15213122|gb|AAK85734.1| beta-G spectrin [Brugia malayi]
Length = 2339
Score = 3386 bits (8780), Expect = 0.0
Identities = 1706/2314 (73%), Positives = 1923/2314 (82%), Gaps = 78/2314 (3%)
Frame = +1
Query: 22 SGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMD 201
+G E+YD+NSSARLFERSRIKALADERE VQKKTFTKWVNSHL+ V+CK+ DLYMD
Sbjct: 13 NGRIEDYEEYDENSSARLFERSRIKALADERENVQKKTFTKWVNSHLLPVNCKIHDLYMD 72
Query: 202 MRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDG 381
MRDGKML+RLL VLSGERLPKPT G+MRIHCLENV+KGLQFLR+QHVHLENLGSHD+VDG
Sbjct: 73 MRDGKMLIRLLEVLSGERLPKPTRGRMRIHCLENVDKGLQFLRDQHVHLENLGSHDVVDG 132
Query: 382 NSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTS 561
N RLTLGLIWTIILRFQIQDITFEDADN ETRSAKEALLLWCQMKTAGYPNVNV+NFSTS
Sbjct: 133 NPRLTLGLIWTIILRFQIQDITFEDADNQETRSAKEALLLWCQMKTAGYPNVNVRNFSTS 192
Query: 562 WRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQP 741
WRDGLAFNALIHKHRPDL++Y+ LQKSNALYNL +AF+ AE QLGL KFLD EDVN+D P
Sbjct: 193 WRDGLAFNALIHKHRPDLIEYEKLQKSNALYNLSNAFEIAEQQLGLIKFLDPEDVNIDMP 252
Query: 742 DEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVI-NELMENDKMINRYETLSSDLLEWINA 918
DEKSIITYVVTYYHYFNK+KQ+ IQGKRIGKV+ NEL+EN+K+IN YE LSSDLLEWI
Sbjct: 253 DEKSIITYVVTYYHYFNKMKQETIQGKRIGKVVVNELVENEKLINNYERLSSDLLEWIRQ 312
Query: 919 KIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRP 1098
I+ LN+RHF N+L GVQ+QL EFN+YRTQEKPPKF+EKGELEVLLFT++S MRANNQRP
Sbjct: 313 TIESLNDRHFVNSLNGVQKQLAEFNNYRTQEKPPKFNEKGELEVLLFTIRSRMRANNQRP 372
Query: 1099 FVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTE 1278
++PR+GKLIADINRAW++LE+AEHEREL LKEE+IRQEKLEQLAARF+RKA MRETWL+E
Sbjct: 373 YLPRDGKLIADINRAWENLERAEHERELALKEEIIRQEKLEQLAARFDRKASMRETWLSE 432
Query: 1279 NQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKIN 1458
NQRLVSQDNFG DL+SVEAATKKHEAIETDI+AYEER NYHD +IN
Sbjct: 433 NQRLVSQDNFGTDLASVEAATKKHEAIETDIYAYEERVQAVVAVAGELEAENYHDIDRIN 492
Query: 1459 ERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHL 1638
+RKENV ARRVRLELSMA+Q+IFH IK RLLSEDLG HL
Sbjct: 493 DRKENVLRLWNYLLELLLARRVRLELSMAVQRIFHEMVYVLDWCDEIKVRLLSEDLGQHL 552
Query: 1639 MDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVL 1818
MDVEDLLQKH+LLESDINI+G RV N +QA++F P+GPDGSGYKPVEP ++ER +L
Sbjct: 553 MDVEDLLQKHSLLESDINIVGNRVKNVNSQAEKFALPNGPDGSGYKPVEPSLVEERMQIL 612
Query: 1819 QKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHL 1998
RY EL +LA ERKRRLEDNKRLCQFWWDV ELEH +K+ EQVL+S DTGRD+V+VS L
Sbjct: 613 LDRYAELNELAVERKRRLEDNKRLCQFWWDVDELEHNLKDMEQVLTSPDTGRDMVSVSLL 672
Query: 1999 LAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASR 2178
LAKHKNAE +L + K LD L+ G++LQ+E IPG++ I RLA IRDY NKLKEL+A R
Sbjct: 673 LAKHKNAEQSLDIVGKRLDDLENEGQQLQEEKIPGAEAINSRLATIRDYFNKLKELAAER 732
Query: 2179 KERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNF 2358
RL+GGV YYQFF DADDVD YL DTLR++ SEDVGKDEGTVQLL+KKHDDV D+L F
Sbjct: 733 HVRLSGGVNYYQFFNDADDVDAYLVDTLRLVGSEDVGKDEGTVQLLIKKHDDVSDDLLKF 792
Query: 2359 DQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYS 2538
+++IK LH +AESLP EAREHPD+R+RLD T ++KAELE L++LRKQRL+DALSLYKL+S
Sbjct: 793 EENIKQLHMQAESLPPEAREHPDVRRRLDMTERRKAELEELARLRKQRLLDALSLYKLFS 852
Query: 2539 DADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLL 2718
DAD +E+WIDEKGKLLATLVP D+EEVEIMKHRF+TLE DM NQ AKV VN+LARQLL
Sbjct: 853 DADIIEAWIDEKGKLLATLVPTDDLEEVEIMKHRFETLEADMNNQAAKVATVNELARQLL 912
Query: 2719 NVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTR 2898
+V+HPNSD+IL RQNKLNARWAQLRDMVDQKR+EL++AHRLETFRIDCQETV+WIEDKTR
Sbjct: 913 HVDHPNSDEILQRQNKLNARWAQLRDMVDQKRSELDQAHRLETFRIDCQETVSWIEDKTR 972
Query: 2899 VLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIRED 3078
VLED+D LTNDL+GVMKLQRRLSMMERDLGAIQAKLDSL KEA +IE+E+P +A IRED
Sbjct: 973 VLEDADELTNDLTGVMKLQRRLSMMERDLGAIQAKLDSLQKEASEIEKEKPADAAQIRED 1032
Query: 3079 IKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAE 3258
IKRIH WDILN++VREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASE+EPQSLA+
Sbjct: 1033 IKRIHIAWDILNRRVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEDEPQSLAD 1092
Query: 3259 AEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQR 3438
AEQLLNQHAAIREEIDGYAEDY KMRAMGDRVTQDQTDPQYMFLRQRL GL+EGWEELQR
Sbjct: 1093 AEQLLNQHAAIREEIDGYAEDYVKMRAMGDRVTQDQTDPQYMFLRQRLVGLEEGWEELQR 1152
Query: 3439 MWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFIT 3618
MWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYL+KD+ P SLEQAEN LKRHQDF+T
Sbjct: 1153 MWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLSKDETPTSLEQAENMLKRHQDFLT 1212
Query: 3619 TMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALS 3798
TMDANDEKI+AV FGDQLC DGHY+ADKIHKKARNI+ERR ANREKA KLKD+L+
Sbjct: 1213 TMDANDEKIKAVVSFGDQLCSDGHYSADKIHKKARNIEERREANREKAVLSFNKLKDSLA 1272
Query: 3799 LQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHA 3978
LQQFLSDC+ELREWIEEKMIRAQDETYRDAKTITSKF+RHQAFQSEL +N+ERL QL+HA
Sbjct: 1273 LQQFLSDCEELREWIEEKMIRAQDETYRDAKTITSKFMRHQAFQSELQSNRERLVQLRHA 1332
Query: 3979 AINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWA 4158
A+ L ++KPE+ GTIDPQI +L+ QW++LEKTTEEKGQKLFDANRQQLYVQSI+DMK+WA
Sbjct: 1333 AVRLAEEKPEFLGTIDPQIADLSIQWEQLEKTTEEKGQKLFDANRQQLYVQSISDMKDWA 1392
Query: 4159 TQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELEN 4338
QL+ +MT ED DLTTVNVAMQKQ +IE+EM+K+A ID HP+E+E
Sbjct: 1393 EQLQQQMTVEDTGQDLTTVNVAMQKQQMIESEMVKRAAQIDSLQQMEPQLEEMHPEEVEA 1452
Query: 4339 IKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGE 4518
IKAHRLAVQEQLQRLQAPLDDRR+ LERKK A+QF RDV+DEKLW +ERL L +AQ +GE
Sbjct: 1453 IKAHRLAVQEQLQRLQAPLDDRRRQLERKKRAYQFLRDVEDEKLWCAERLPLTQAQEIGE 1512
Query: 4519 SLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQE 4698
+L DC+RLQK +Q L +EIDNHEPWI +IC NG+E+IDEGH + F++KI EL WQ
Sbjct: 1513 NLFDCNRLQKKMQSLKHEIDNHEPWIEKICQNGREMIDEGHEHRSEFQQKIDELMKIWQN 1572
Query: 4699 LKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHER 4878
LK+ + RK L ESE+AHQFLYDC EAEAWMSEQELYMMQDERGKDEFST+NQIK HER
Sbjct: 1573 LKDCLDARKEHLAESERAHQFLYDCNEAEAWMSEQELYMMQDERGKDEFSTENQIKNHER 1632
Query: 4879 LQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXX 5058
LQ DI+++ADTIR LAT+A KFV+EK PL E I VRQAQIEKLYAGLQD
Sbjct: 1633 LQQDINQYADTIRNLATQAQKFVDEKRPLWEHINVRQAQIEKLYAGLQDLCKERRKRLDE 1692
Query: 5059 XXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVA 5238
Y LHREIDDLLQWIADKE+VAGSQE GQDYEHVQML ERF QFARDTENIG +RVA
Sbjct: 1693 TLQLYELHREIDDLLQWIADKELVAGSQEPGQDYEHVQMLIERFLQFARDTENIGLDRVA 1752
Query: 5239 NANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
NAND CD LI GH+DAPT+ALWKDSLNEAWENLLEL+DTR Q+LEASR+LHKF+HDCRD
Sbjct: 1753 NANDACDHLIATGHSDAPTVALWKDSLNEAWENLLELIDTRMQMLEASRMLHKFFHDCRD 1812
Query: 5419 CLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAG 5598
CLSRI+EK H++P+DLGRDSSSVGAL RKHQN+LKDI AIG+QVAQIERDA ELRD YAG
Sbjct: 1813 CLSRILEKNHSIPEDLGRDSSSVGALKRKHQNFLKDIEAIGQQVAQIERDALELRDAYAG 1872
Query: 5599 DKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNS 5778
D+A++IG+RE+EV KAWR LR +CDAR+ RL DTSDLF+FM MVRDLLLWM+EVKREM S
Sbjct: 1873 DRAIEIGAREAEVQKAWRQLRAVCDARSMRLGDTSDLFRFMIMVRDLLLWMNEVKREMTS 1932
Query: 5779 QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT 5958
QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT
Sbjct: 1933 QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT 1992
Query: 5959 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWL AQEPYL+SKEYGRNLEETIKLI
Sbjct: 1993 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLMAQEPYLVSKEYGRNLEETIKLI 2052
Query: 6139 KKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRG----------------- 6267
KKHEAFEKSA AQEERFLALEKLTTFELKE Q R+ E +RR
Sbjct: 2053 KKHEAFEKSANAQEERFLALEKLTTFELKEMQRRDMEEVERRALSGPSGDVRRGTLQRTS 2112
Query: 6268 -------PAHIGSPSRSTPAAETSFGAQD-DGAKQGEAFEGTLIRKHTY----------- 6390
PA P P FG ++ GTL++K Y
Sbjct: 2113 TAAAGERPAEAALPMERGPQTSDDFGDENLHDTTMSSCDSGTLLQKTRYIAERNSRLMAS 2172
Query: 6391 ---------------------------------------ESLDRKAANRSWEKLYAVLRQ 6453
ESLDRKA++RSWEK+Y VLR
Sbjct: 2173 ESSGWRLSLSRSARFDIHDLRGVDVGGAFEGVLIRKHTYESLDRKASSRSWEKVYTVLRG 2232
Query: 6454 NELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGS 6627
++L+F+KD KH +E++ H E P+ L GCSV+VA++Y KKKNVLSL+ P GAEYL Q S
Sbjct: 2233 SQLAFFKDQKHMEENILFHAEEPLNLEGCSVSVAAEYTKKKNVLSLKSPTGAEYLLQTAS 2292
Query: 6628 EEDMQRWLTELQVATGQAQLEEASRSQTLPAEGS 6729
+EDM+RWL LQ+ATGQ+Q E +RSQTLP EGS
Sbjct: 2293 DEDMERWLRRLQLATGQSQGEVVARSQTLPVEGS 2326
>gi|17647191|ref|NP_523388.1| CG5870-PA [Drosophila melanogaster]
gi|14286182|sp|Q00963|SPCB_DROME Spectrin beta chain
gi|7293373|gb|AAF48751.1| CG5870-PA [Drosophila melanogaster]
Length = 2291
Score = 2502 bits (6485), Expect = 0.0
Identities = 1269/2263 (56%), Positives = 1650/2263 (72%), Gaps = 28/2263 (1%)
Frame = +1
Query: 16 GNSGAYTQDEDYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDL 192
G Y + +YD NSS+RLFERSRIKALA+ERE VQKKTFTKWVNSHL RV+C++ DL
Sbjct: 15 GPGNEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADL 74
Query: 193 YMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDI 372
Y+DMRDGK L++LL VLSGERLPKPT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDI
Sbjct: 75 YVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDI 134
Query: 373 VDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNF 552
VDGN+ L LGLIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF
Sbjct: 135 VDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNF 194
Query: 553 STSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNV 732
+TSWRDGLAFNA+IHKHRPDLV ++ L K+NA++NL +AFD AE++LGLAK LDAEDV V
Sbjct: 195 TTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFV 254
Query: 733 DQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWI 912
+ PDEKSIITYVVTYYHYF+KLKQ+ +QGKRIGKV+ MENDKM++ YE +SDLL+WI
Sbjct: 255 EHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWI 314
Query: 913 NAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQ 1092
IQ L ER FEN+L GVQ QL +F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ
Sbjct: 315 ETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQ 374
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
+P+ P+EGK+I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARF+RKA MRETWL
Sbjct: 375 KPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWL 434
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
+ENQRLVSQDNFG DL++VEAA KKHEAIETDIFAYEER YHD +
Sbjct: 435 SENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKR 494
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I RK+NV ARR+RLE+S+ +Q+ F IK L+++D G
Sbjct: 495 ILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGK 554
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HLM VEDLLQKH+L+E+DINI+GERV + +Q+F + D YKP +P I R
Sbjct: 555 HLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLS---DDPESYKPCDPEIIVSRVQ 611
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
L+ Y EL+ LA ER+ RLE++++L QF+WD A+ E+ IKE+EQ++S+ + G D+ TV+
Sbjct: 612 QLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVN 671
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSA 2172
+L+KHK E+ + + L + G EL E G+D I RL EI + + L +L+
Sbjct: 672 LMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTK 731
Query: 2173 SRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQ 2352
R++RL VEY+Q F DADDVD ++ DTLR++SSEDVG+DE VQ LLKKH DV DEL+
Sbjct: 732 YRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELK 791
Query: 2353 NFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKL 2532
N+ + I LH +AESL E ++ +RL+ + EL L++LRKQRL+DALSLYKL
Sbjct: 792 NYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKL 851
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
S+AD VE WI EK K+L T+ PG+DIE+VEIMKHRF+ +++M ++V VN LARQ
Sbjct: 852 MSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQ 911
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
LL+VEHPNSD+IL RQN LN W+ LR+ + K ++L+ AH ++TF I+C+ET++WIEDK
Sbjct: 912 LLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDK 971
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
R+L ++D+L DL+GVM LQRRLS M+RDL AIQAKL SL +EA+ IE E P+EA+ IR
Sbjct: 972 KRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIR 1031
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
E I +I +W+ L + ++E ++KL+EAGDL RFLRDLDHFQ WLT TQ VASE+ P SL
Sbjct: 1032 ERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSL 1091
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD---QTDPQYMFLRQRLAGLQEGW 3423
EAE+LLNQH +IREEID Y EDYK M G+R+T + DPQYMFLR+RL L++GW
Sbjct: 1092 PEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGW 1151
Query: 3424 EELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRH 3603
EEL +MW+NRQ LLSQ L+ Q+F RDA+Q EV+LSQQE++L+KDD P +LEQAENQLKRH
Sbjct: 1152 EELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRH 1211
Query: 3604 QDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKL 3783
+ F+TTM+AND+KI + D L + H+ ADKI K+A NI RR NR++A + +KL
Sbjct: 1212 EAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKL 1271
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLD 3963
K+ + L +FL D +EL EW++EK +QDE+YR AKTI SK+ RHQAF++E+AANKERL
Sbjct: 1272 KNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLF 1331
Query: 3964 QLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIAD 4143
+ + +A L +KPE+ I+P+++ELA Q+D+LE T+EKG LFDANR+ L Q+ D
Sbjct: 1332 EAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDD 1391
Query: 4144 MKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
+ + T LE ++ D DLT+VN+ MQKQ +I+T+M KA+ ++ P
Sbjct: 1392 IDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVP 1451
Query: 4324 DE-LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
+E +E I + AV E+ ++++APL +R+KALE+KK AFQF RDV+DEKLWI E+L +A
Sbjct: 1452 EEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPVAN 1511
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
+ + G SL + H L+K Q L+ EIDNHEP IN ICNNG++LIDEGH + FE I +L
Sbjct: 1512 SPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDL 1571
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
WQELK+A+++R+ L ESEK Q+ +D EAE+WMSEQELYMM ++RGKDE S +N
Sbjct: 1572 TQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDEISAQNL 1631
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
+KKHE L+ ++ +A+TIR L A +F + + + V+Q+Q++KLYAGL+D
Sbjct: 1632 MKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGER 1691
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
+ L RE+DDL QWI D+EVVAGSQE GQD++HV +L ERF +FARDTE +
Sbjct: 1692 RARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAV 1751
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
G ERVA N D LI GH+D+ TIA WKD+LNE+W++LLEL++TR Q+L ASR LHKF
Sbjct: 1752 GGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKF 1811
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
+HDC+D L RI+EK H + D+LGRD+ SV L RKH N+L+D+ + QV QI+ ++A+L
Sbjct: 1812 FHDCKDVLGRILEKQHGVSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKL 1871
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
+D YAGDKA +I +RE EV+ AW +L+ +CDAR +L DT DLF+F NMVR L++WM+++
Sbjct: 1872 QDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDL 1931
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
R+MN+ E+P+DVSGVELLMNNHQSLKAEID RE+NF ACISLG++LL R HYAS++I+
Sbjct: 1932 VRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKD 1991
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
+L+ L+ R ++RRWE+RWE LQLILEVYQFARDAAVAE+WL AQEPYL+S E G ++
Sbjct: 1992 RLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTID 2051
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREE--ETAKRRGPAHIGSPSR 6294
E LIKKHEAFEKSA AQEERF ALE+LTTFELKE + R+E E A+R+
Sbjct: 2052 EVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKRRQELAEEAERQRIKEEQEAKA 2111
Query: 6295 STPAAE-----------TSFGAQDDGAKQ------GEAFEGTLIRKHTYESLDRKAANRS 6423
++ AAE GA D +++ GE EG + RKH ++S +KA+NRS
Sbjct: 2112 ASEAAEQAKREAERRDDVDVGASHDDSERGGTPGAGEGHEGYVTRKHEWDSTTKKASNRS 2171
Query: 6424 WEKLYAVLRQNELSFYKDPK----HRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRL 6591
W+K+Y + +SFYKD K + + + GEP L ++ +ASDY KKK+VL ++L
Sbjct: 2172 WDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKL 2231
Query: 6592 PIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPA 6720
GA +L Q + +M +W+T L+ A + ASRSQTLPA
Sbjct: 2232 ANGALFLLQAHDDTEMSQWVTSLK-AQSDSTAVAASRSQTLPA 2273
>gi|423777|pir||A46147 spectrin beta chain - fruit fly (Drosophila
melanogaster)
gi|157020|gb|AAA28399.1| beta-spectrin
Length = 2291
Score = 2502 bits (6485), Expect = 0.0
Identities = 1269/2263 (56%), Positives = 1650/2263 (72%), Gaps = 28/2263 (1%)
Frame = +1
Query: 16 GNSGAYTQDEDYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDL 192
G Y + +YD NSS+RLFERSRIKALA+ERE VQKKTFTKWVNSHL RV+C++ DL
Sbjct: 15 GPGNEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADL 74
Query: 193 YMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDI 372
Y+DMRDGK L++LL VLSGERLPKPT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDI
Sbjct: 75 YVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDI 134
Query: 373 VDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNF 552
VDGN+ L LGLIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF
Sbjct: 135 VDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNF 194
Query: 553 STSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNV 732
+TSWRDGLAFNA+IHKHRPDLV ++ L K+NA++NL +AFD AE++LGLAK LDAEDV V
Sbjct: 195 TTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFV 254
Query: 733 DQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWI 912
+ PDEKSIITYVVTYYHYF+KLKQ+ +QGKRIGKV+ MENDKM++ YE +SDLL+WI
Sbjct: 255 EHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWI 314
Query: 913 NAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQ 1092
IQ L ER FEN+L GVQ QL +F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ
Sbjct: 315 ETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQ 374
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
+P+ P+EGK+I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARF+RKA MRETWL
Sbjct: 375 KPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWL 434
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
+ENQRLVSQDNFG DL++VEAA KKHEAIETDIFAYEER YHD +
Sbjct: 435 SENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKR 494
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I RK+NV ARR+RLE+S+ +Q+ F IK L+++D G
Sbjct: 495 ILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGK 554
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HLM VEDLLQKH+L+E+DINI+GERV + +Q+F + D YKP +P I R
Sbjct: 555 HLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLS---DDPESYKPCDPEIIVSRVQ 611
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
L+ Y EL+ LA ER+ RLE++++L QF+WD A+ E+ IKE+EQ++S+ + G D+ TV+
Sbjct: 612 QLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVN 671
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSA 2172
+L+KHK E+ + + L + G EL E G+D I RL EI + + L +L+
Sbjct: 672 LMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTK 731
Query: 2173 SRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQ 2352
R++RL VEY+Q F DADDVD ++ DTLR++SSEDVG+DE VQ LLKKH DV DEL+
Sbjct: 732 YRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELK 791
Query: 2353 NFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKL 2532
N+ + I LH +AESL E ++ +RL+ + EL L++LRKQRL+DALSLYKL
Sbjct: 792 NYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKL 851
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
S+AD VE WI EK K+L T+ PG+DIE+VEIMKHRF+ +++M ++V VN LARQ
Sbjct: 852 MSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQ 911
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
LL+VEHPNSD+IL RQN LN W+ LR+ + K ++L+ AH ++TF I+C+ET++WIEDK
Sbjct: 912 LLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDK 971
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
R+L ++D+L DL+GVM LQRRLS M+RDL AIQAKL SL +EA+ IE E P+EA+ IR
Sbjct: 972 KRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIR 1031
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
E I +I +W+ L + ++E ++KL+EAGDL RFLRDLDHFQ WLT TQ VASE+ P SL
Sbjct: 1032 ERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSL 1091
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD---QTDPQYMFLRQRLAGLQEGW 3423
EAE+LLNQH +IREEID Y EDYK M G+R+T + DPQYMFLR+RL L++GW
Sbjct: 1092 PEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGW 1151
Query: 3424 EELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRH 3603
EEL +MW+NRQ LLSQ L+ Q+F RDA+Q EV+LSQQE++L+KDD P +LEQAENQLKRH
Sbjct: 1152 EELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRH 1211
Query: 3604 QDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKL 3783
+ F+TTM+AND+KI + D L + H+ ADKI K+A NI RR NR++A + +KL
Sbjct: 1212 EAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKL 1271
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLD 3963
K+ + L +FL D +EL EW++EK +QDE+YR AKTI SK+ RHQAF++E+AANKERL
Sbjct: 1272 KNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLF 1331
Query: 3964 QLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIAD 4143
+ + +A L +KPE+ I+P+++ELA Q+D+LE T+EKG LFDANR+ L Q+ D
Sbjct: 1332 EAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDD 1391
Query: 4144 MKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
+ + T LE ++ D DLT+VN+ MQKQ +I+T+M KA+ ++ P
Sbjct: 1392 IDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVP 1451
Query: 4324 DE-LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
+E +E I + AV E+ ++++APL +R+KALE+KK AFQF RDV+DEKLWI E+L +A
Sbjct: 1452 EEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPVAN 1511
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
+ + G SL + H L+K Q L+ EIDNHEP IN ICNNG++LIDEGH + FE I +L
Sbjct: 1512 SPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDL 1571
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
WQELK+A+++R+ L ESEK Q+ +D EAE+WMSEQELYMM ++RGKDE S +N
Sbjct: 1572 TQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDEISAQNL 1631
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
+KKHE L+ ++ +A+TIR L A +F + + + V+Q+Q++KLYAGL+D
Sbjct: 1632 MKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGER 1691
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
+ L RE+DDL QWI D+EVVAGSQE GQD++HV +L ERF +FARDTE +
Sbjct: 1692 RARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAV 1751
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
G ERVA N D LI GH+D+ TIA WKD+LNE+W++LLEL++TR Q+L ASR LHKF
Sbjct: 1752 GGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKF 1811
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
+HDC+D L RI+EK H + D+LGRD+ SV L RKH N+L+D+ + QV QI+ ++A+L
Sbjct: 1812 FHDCKDVLGRILEKQHGVSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKL 1871
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
+D YAGDKA +I +RE EV+ AW +L+ +CDAR +L DT DLF+F NMVR L++WM+++
Sbjct: 1872 QDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDL 1931
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
R+MN+ E+P+DVSGVELLMNNHQSLKAEID RE+NF ACISLG++LL R HYAS++I+
Sbjct: 1932 VRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKD 1991
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
+L+ L+ R ++RRWE+RWE LQLILEVYQFARDAAVAE+WL AQEPYL+S E G ++
Sbjct: 1992 RLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTID 2051
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREE--ETAKRRGPAHIGSPSR 6294
E LIKKHEAFEKSA AQEERF ALE+LTTFELKE + R+E E A+R+
Sbjct: 2052 EVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKRRQELAEEAERQRIKEEQEAKA 2111
Query: 6295 STPAAE-----------TSFGAQDDGAKQ------GEAFEGTLIRKHTYESLDRKAANRS 6423
++ AAE GA D +++ GE EG + RKH ++S +KA+NRS
Sbjct: 2112 ASEAAEQAKREAERRDDVDVGASHDDSERGGTPGAGEGHEGYVTRKHEWDSTTKKASNRS 2171
Query: 6424 WEKLYAVLRQNELSFYKDPK----HRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRL 6591
W+K+Y + +SFYKD K + + + GEP L ++ +ASDY KKK+VL ++L
Sbjct: 2172 WDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKL 2231
Query: 6592 PIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPA 6720
GA +L Q + +M +W+T L+ A + ASRSQTLPA
Sbjct: 2232 ANGALFLLQAHDDTEMSQWVTSLK-AQSDSTAVAASRSQTLPA 2273
>gi|31201697|ref|XP_309796.1| ENSANGP00000012507 [Anopheles gambiae]
gi|30178367|gb|EAA05634.2| ENSANGP00000012507 [Anopheles gambiae str.
PEST]
Length = 2296
Score = 2487 bits (6447), Expect = 0.0
Identities = 1255/2270 (55%), Positives = 1638/2270 (71%), Gaps = 35/2270 (1%)
Frame = +1
Query: 16 GNSGAYTQDEDYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDL 192
G + +D +YD NSS+RLFERSRIKALA+ERE VQKKTFTKWVNSHLVRV+ ++DL
Sbjct: 15 GPGNEFIEDIEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLVRVNSPIKDL 74
Query: 193 YMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDI 372
Y+DMRDGK L++LL VLSGERLP+PT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDI
Sbjct: 75 YVDMRDGKNLIKLLEVLSGERLPRPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDI 134
Query: 373 VDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNF 552
VDGN+ L LGLIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF
Sbjct: 135 VDGNASLNLGLIWTIILRFQIQDITIEETDNKETKSAKDALLLWCQMKTAGYHNVNVRNF 194
Query: 553 STSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNV 732
+TSWRDGLAFNA+IHKHRPDL+ +D L K+N + NL +AF+ AE +LGL K LDAED+ V
Sbjct: 195 TTSWRDGLAFNAIIHKHRPDLIQFDKLSKTNPIQNLNNAFNVAEEKLGLTKLLDAEDIFV 254
Query: 733 DQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWI 912
D PDEKSIITYVVTYYHYF+KLKQ+ +QGKRIGKV+ M+ND+MIN YE+L+S+LL+WI
Sbjct: 255 DHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMDNDRMINEYESLTSELLKWI 314
Query: 913 NAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQ 1092
I L +RHF N+L GVQ+QL +F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ
Sbjct: 315 EVTIVQLGDRHFVNSLVGVQQQLAQFSNYRTVEKPPKFVEKGNLEVLLFTLQSKMRANNQ 374
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
+P+ P+EGK+I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARFNRKA MRETWL
Sbjct: 375 KPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFNRKATMRETWL 434
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
+ENQRLVS DNFG DL++VEAA KKHEAIETDIFAYEER YHD +
Sbjct: 435 SENQRLVSTDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCNELEAEKYHDIER 494
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I RK+NV ARR+RLE S+ +Q+ F IK RLL++D G
Sbjct: 495 IAARKDNVLRLWNYLIELLRARRMRLEFSIQLQQNFQEMIYILDSMEEIKQRLLTDDYGK 554
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HLM VEDLLQKH+L+E+DIN++G+RV + +Q+F + YKP +P I +R
Sbjct: 555 HLMGVEDLLQKHSLVEADINVLGDRVKQVVQNSQKFL---VDEEDNYKPCDPSIIVDRVQ 611
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
L+ Y EL LA ER+ RLE+N++L QF+WD+A+ E+ IKE+EQ++S+ + G D+ TV+
Sbjct: 612 RLEDAYAELCKLAVERRSRLEENRKLWQFYWDMADEENWIKEKEQIVSADEIGHDLTTVN 671
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSA 2172
LL+KHK E+ ++ E L + G EL G+D I RL EI + L+EL+
Sbjct: 672 LLLSKHKALESEIQSHEPQLMAVSEVGDELVRRGHFGADRIDERLKEILAMWSNLRELTE 731
Query: 2173 SRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQ 2352
R++RL V+Y+Q F DADD+D ++ D LR++SSEDVG+DE VQ LLKKH DV DEL+
Sbjct: 732 YRRKRLEDAVDYFQLFADADDIDNWMLDALRLVSSEDVGRDEANVQSLLKKHKDVADELK 791
Query: 2353 NFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKL 2532
N+ + I+ LHA+A+ L E + +RL + EL L++LRKQRL+DALSLYKL
Sbjct: 792 NYAETIEQLHAQAKRLTLNEPEQERVNERLAAIDNRYRELMELAKLRKQRLLDALSLYKL 851
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
S++D VE WI EK ++L T+VPG+DIE+VEIMKHR+D +++M ++V VN LARQ
Sbjct: 852 ISESDGVEQWIGEKERMLQTMVPGKDIEDVEIMKHRYDGFDKEMNANASRVAVVNQLARQ 911
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
LL+VEHPNS +I+ RQN LN W++LR+ + KR++L+ AH ++TF I+C+ETV+WIEDK
Sbjct: 912 LLHVEHPNSPEIIERQNHLNNSWSKLREQAESKRDDLKSAHGVQTFYIECRETVSWIEDK 971
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
R+L ++D+L DL+GVM LQRRLS MERDL AIQAKL +L EAD IE + P+EA IR
Sbjct: 972 KRILTETDSLQMDLTGVMTLQRRLSGMERDLAAIQAKLTALENEADAIEGDHPEEAALIR 1031
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
E + I +W+ L + ++E ++KL+EAGDL RFLRDLDHFQAWLT TQ VASE+ P SL
Sbjct: 1032 ERVATIQTIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQAWLTKTQTDVASEDTPTSL 1091
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQT---DPQYMFLRQRLAGLQEGW 3423
EAE+LLNQH +IREEID Y EDYKKM G+ +T + T DPQYMFLR+RL L++GW
Sbjct: 1092 PEAEKLLNQHQSIREEIDNYTEDYKKMMDYGEGLTSEPTQTEDPQYMFLRERLKALKDGW 1151
Query: 3424 EELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRH 3603
EEL +MW+NRQ LLSQGL+ Q+F RDA+QAEV+LSQQE+ L+KDD P +LEQAENQLKRH
Sbjct: 1152 EELHQMWENRQVLLSQGLDQQLFNRDARQAEVLLSQQEHVLSKDDTPVNLEQAENQLKRH 1211
Query: 3604 QDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKL 3783
+ F+TTM+ANDEK + Q+ H+ ADKI K+A +I RR NR +A E+ +KL
Sbjct: 1212 EAFLTTMEANDEKFNTIVQVAGQMTSKDHFDADKITKRAESIAHRRDDNRNRALELHEKL 1271
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLD 3963
K+ + L +FL D +EL EW++EK I AQD+TYR AKT+ SK+ RHQAF++E+AANKERL
Sbjct: 1272 KNQVKLHEFLQDIEELTEWVQEKYITAQDDTYRSAKTVHSKWTRHQAFEAEIAANKERLH 1331
Query: 3964 QLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIAD 4143
+ K AA L +KPE+ I+P++ +L+ +DELE +T+EKG LFDA R+ + QS+ D
Sbjct: 1332 EAKKAAQELMVEKPEFKEIIEPKLTDLSKNFDELETSTKEKGALLFDAKREVIVQQSVDD 1391
Query: 4144 MKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
+ W LE ++ D DLT+VN+ MQKQ +I+T+M KA+ ++ P
Sbjct: 1392 IDSWMDDLEKQIINTDTGNDLTSVNILMQKQQIIQTQMAVKARQVEELDKQTEVLTKTAP 1451
Query: 4324 -DELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
D LE I + AV + ++++APL +R++ LE+KK AFQF RDV+DEKLWI E++ LA+
Sbjct: 1452 SDVLEPIVEKKTAVNARFEKIKAPLLERQRQLEKKKEAFQFRRDVEDEKLWIDEKMPLAE 1511
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
+ G SL + H L+K Q L+ EIDNHEP I ICNNGQ+LIDEGH + ++ I +L
Sbjct: 1512 STEYGNSLFNVHVLKKKHQSLNTEIDNHEPRIMTICNNGQKLIDEGHEDAGSYADLISQL 1571
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
WQELK+AV++R L +SEK Q+ +D EAE+WMSEQELYMM ++RGKDE S +N
Sbjct: 1572 TQKWQELKDAVENRHRQLDQSEKVQQYFFDAAEAESWMSEQELYMMVEDRGKDETSAQNL 1631
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
+KKHE L+ ++ +ADTIR L A + E+ ++Q+ V+Q+Q++KLYAGL+D
Sbjct: 1632 MKKHESLEQSVEDYADTIRQLGETARQLTTEQHAYSDQVSVKQSQLDKLYAGLKDLAGER 1691
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
+ L RE+DDL QWI D+EVVAGS E GQDY+H+ +L ERF +FA+DT +
Sbjct: 1692 RARLDEALQLFMLSREVDDLEQWITDREVVAGSHELGQDYDHITLLWERFNEFAQDTATV 1751
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
GSERVA AN D LI GH+D+ TIA WKD LNE+W++LLEL++TR +L ASR LHKF
Sbjct: 1752 GSERVAKANGIADDLIHAGHSDSATIAEWKDGLNESWQDLLELIETRKAMLAASRELHKF 1811
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
+HDC+D L RI EK H + ++LGRD+ V AL RKHQN+++D+ + QV QI+ ++A+L
Sbjct: 1812 FHDCKDVLGRINEKQHGVSEELGRDAGVVSALQRKHQNFIQDLMTLHSQVQQIQEESAKL 1871
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
+ YAG+KA +I +RE EV+ AW HL+ +C+ R +L DT DLFKF NMVR L+LWM++V
Sbjct: 1872 QAAYAGEKAREITNREHEVLNAWAHLQSMCEERRGKLADTGDLFKFFNMVRTLMLWMEDV 1931
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
R+MN+ E+P+DVSGVELLMNNHQSLKAEID RE+NF+AC++LG++LL+R HYAS++I+
Sbjct: 1932 VRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFSACLALGKELLSRNHYASADIKD 1991
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
+L++LT R ++ RWE+RWE LQLILEVYQFARDAAVAE+WL AQEPYL+S E G ++
Sbjct: 1992 RLLQLTNSRNALLHRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLMSTELGHTID 2051
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHRE------------------- 6243
E LIKKHEAFEKSA AQEERF ALE+LTTFELKE + R+
Sbjct: 2052 EVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKRRQDAAEEAERQRLEAEAAAAR 2111
Query: 6244 -----EETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRK 6408
E A R+ A + P + S Q+ G A EG L RKH +ES +K
Sbjct: 2112 AAAEAEAEAIRQQEAAAARDAADAPGSPHSTREQESGGADEGAQEGILTRKHEWESTTKK 2171
Query: 6409 AANRSWEKLYAVLRQNELSFYKDPKHR----DESVHGEPPMALPGCSVNVASDYQKKKNV 6576
A+NRSW+K+Y V R L+F+KD + +++ GEPP+ L G + +ASDY KKK+V
Sbjct: 2172 ASNRSWDKVYCVARSGRLTFFKDQRSAKSVPEQTFRGEPPLELKGAQIEIASDYTKKKHV 2231
Query: 6577 LSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEA--SRSQTLPA 6720
++L G E+L QC + +MQ+W+T L+ Q +L+ + RS TLPA
Sbjct: 2232 FRIKLSNGGEFLLQCHDDAEMQQWVTALK---AQCELDASGEGRSLTLPA 2278
>gi|48101779|ref|XP_395212.1| similar to ENSANGP00000012507 [Apis
mellifera]
Length = 2465
Score = 2453 bits (6357), Expect = 0.0
Identities = 1229/2118 (58%), Positives = 1588/2118 (74%), Gaps = 15/2118 (0%)
Frame = +1
Query: 46 DYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKML 222
+YD NSS+RLFERSRIKALA ERELVQKKTF KWVNSHLVR SC++ DLY+D+RDGKML
Sbjct: 25 EYDGGNSSSRLFERSRIKALAGERELVQKKTFQKWVNSHLVRCSCRIGDLYVDLRDGKML 84
Query: 223 LRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLG 402
++LL +LSGERLP+PT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDIVDGN RL+LG
Sbjct: 85 IKLLEILSGERLPRPTKGKMRIHCLENVDKALQFLREQRVHLENMGSHDIVDGNPRLSLG 144
Query: 403 LIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAF 582
LIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF+TSWRDGLAF
Sbjct: 145 LIWTIILRFQIQDITIEETDNQETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAF 204
Query: 583 NALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIIT 762
NA+IHKHRPDL+ ++ L KSNA+YNL +AF+ AE++LGL K LDAED+ VD PDEKSIIT
Sbjct: 205 NAIIHKHRPDLIQFEKLSKSNAIYNLNNAFNVAEDKLGLTKLLDAEDIFVDHPDEKSIIT 264
Query: 763 YVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNER 942
YVVTYYHYF+K+KQ+ +QGKRIGKV+ MEND+MI+ YE+L+SDLL WI I+ L +R
Sbjct: 265 YVVTYYHYFSKMKQETVQGKRIGKVVGIAMENDRMIHEYESLTSDLLRWIEGTIEALGDR 324
Query: 943 HFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKL 1122
F N+L GVQ QL++F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ+P+ P+EGK+
Sbjct: 325 RFANSLVGVQSQLSQFSNYRTVEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKM 384
Query: 1123 IADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQD 1302
I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARFNRKA MRETWL+ENQRLVSQD
Sbjct: 385 ISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFNRKASMRETWLSENQRLVSQD 444
Query: 1303 NFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXX 1482
NFG DL++VEAA KKHEAIETDIFAYEER NYHD +IN RK+NV
Sbjct: 445 NFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVMAVSQELEAENYHDIERINARKDNVLR 504
Query: 1483 XXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQ 1662
ARR+RLELS+ +Q+ F IK RLL++D G HLM VEDLLQ
Sbjct: 505 LWNYLLELLRARRMRLELSLQLQQNFQEMLYILDSMEEIKMRLLTDDYGKHLMGVEDLLQ 564
Query: 1663 KHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELL 1842
KH+L+E+DIN++GERV + Q+QRF + G GY+P +P I ER L+ Y EL+
Sbjct: 565 KHSLVEADINVLGERVKAVVQQSQRFLD----HGEGYRPCDPAIIVERVQQLEDAYAELV 620
Query: 1843 DLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAE 2022
LA ER+ RLE++++L QF+WD+A+ E+ IKE+EQ++S+ D G D+ T++ LL+KHK E
Sbjct: 621 RLAVERRARLEESRKLWQFYWDMADEENWIKEKEQIVSTGDIGHDLTTINLLLSKHKALE 680
Query: 2023 NNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGV 2202
N ++ E L + G EL + GSD I RL EI N L +L+A R++RL V
Sbjct: 681 NEIQSHEPQLMSVAAVGDELVRQKHFGSDRIQERLHEILGMWNHLLDLAAFRRKRLEEAV 740
Query: 2203 EYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLH 2382
+Y+Q F DADD+D ++ DTLR++SSEDVG+DE VQ LLKKH DV DEL+N+ I LH
Sbjct: 741 DYHQLFADADDIDIWMLDTLRLVSSEDVGRDEANVQSLLKKHKDVTDELKNYAATIDQLH 800
Query: 2383 AKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESW 2562
+A SL ++ + P++ +RL + + EL L++LRKQRL+DALSLYKL+S++D VE W
Sbjct: 801 QQASSLGEQDAKSPEVLERLASIDSRYKELMELAKLRKQRLLDALSLYKLFSESDGVEQW 860
Query: 2563 IDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSD 2742
I EK ++L T+VP +DIE+VEIMKHR++ E++M ++V VN LARQLL+VEHPNS+
Sbjct: 861 IGEKNRMLETMVPAKDIEDVEIMKHRYNGFEKEMYANASRVAVVNQLARQLLHVEHPNSE 920
Query: 2743 DILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDAL 2922
I+ RQN+LN +WA+LR+ + KR+EL AH ++TF I+C+ETV+WIEDK R+L+ +D+L
Sbjct: 921 QIVARQNELNQKWAELREKAENKRDELNSAHGVQTFHIECRETVSWIEDKKRILQQTDSL 980
Query: 2923 TNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVW 3102
DL+GVM LQRRLS MERDL AIQAKLD+L EA +I+++ ++ + I+ I +IH +W
Sbjct: 981 EMDLTGVMTLQRRLSGMERDLAAIQAKLDALEMEAQNIQQQNLEDPEVIKGRIDQIHTIW 1040
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
+ L + ++E +AKL+EAGDL RFLRDLDHFQAWLT TQ VASE+ P +LA+AE+LL QH
Sbjct: 1041 EQLTQMLKERDAKLEEAGDLHRFLRDLDHFQAWLTKTQTDVASEDTPTTLADAEKLLTQH 1100
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQD--QTDPQYMFLRQRLAGLQEGWEELQRMWDNRQ 3456
I+EEID Y +DY+KM G+R+T + D QYMFLR+RL L+ GWEEL +MW NR+
Sbjct: 1101 QNIKEEIDNYTDDYQKMMEYGERLTSEAGDGDTQYMFLRERLNALKMGWEELHQMWVNRK 1160
Query: 3457 HLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAND 3636
LLS LNLQ+F RDA+QAEV+LSQQE+ LAKD+ P + EQAE+ +KRH+ F+TTMDAND
Sbjct: 1161 ILLSNSLNLQIFDRDARQAEVLLSQQEHILAKDETPANFEQAEHMIKRHEAFMTTMDAND 1220
Query: 3637 EKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLS 3816
EKI +V + +L +GH+AADK+ +KA +I+ERR NREKA + ++KLKD L LQ FL
Sbjct: 1221 EKINSVVQYAGRLVDEGHFAADKVKRKAESINERRRINREKANQYMEKLKDQLQLQMFLQ 1280
Query: 3817 DCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
DC+EL EW++EK I AQDETYR AKT+ SK+ RHQAF++E+A+NK+RL QL+ AA L
Sbjct: 1281 DCEELGEWVQEKHITAQDETYRSAKTVHSKWTRHQAFEAEIASNKDRLQQLQQAAEELIQ 1340
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENE 4176
KP+ I P++ ELA Q++ELE TT +KG++LFDANR+ L Q+ D+ W +LE +
Sbjct: 1341 QKPDLAEIIKPKVAELADQFEELETTTHDKGERLFDANREVLIHQTCDDIDSWMNELEKQ 1400
Query: 4177 MTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP-DELENIKAHR 4353
+ D DL +VN+ MQKQ +IET+M KA+ + P D++E IK +
Sbjct: 1401 IESTDTGSDLASVNILMQKQQMIETQMAVKARQVTELDKQAEHLQRTVPEDKMEEIKCKK 1460
Query: 4354 LAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
V ++ +L+APL DR++ LE+KK AFQF RDV+DEKLWI+E++ A + G SL +
Sbjct: 1461 EKVAQRFAQLKAPLIDRQRQLEKKKEAFQFRRDVEDEKLWIAEKMPQATSTEYGNSLFNV 1520
Query: 4534 HRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAV 4713
H L+K Q L EI+NHEP IN +CNNGQ+LIDEGH + P F+K I EL W+ELK AV
Sbjct: 1521 HMLKKKNQSLRTEIENHEPRINLVCNNGQKLIDEGHEDSPEFQKLISELTEKWKELKHAV 1580
Query: 4714 KDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDI 4893
DR L ++EKA Q+ +D EAE+WMSEQELYMM ++RGKDE S +N +KKHE L+ +
Sbjct: 1581 DDRNKHLLQNEKAQQYFFDATEAESWMSEQELYMMVEDRGKDEISAQNLMKKHESLEHAV 1640
Query: 4894 DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXY 5073
+ +A+TIR L A + + ++ PL +QI V+Q+Q++KLYAGL+D +
Sbjct: 1641 EDYAETIRQLGETARQLINDQHPLGDQIAVKQSQVDKLYAGLKDLAGERRAKLDEALQLF 1700
Query: 5074 ALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDG 5253
L+RE+DDL QWIA++E+VAGS E GQDY+HV +L ERF++FARDTE IGSERVA N
Sbjct: 1701 MLNREVDDLEQWIAERELVAGSHELGQDYDHVTLLWERFKEFARDTEAIGSERVAAVNGI 1760
Query: 5254 CDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRI 5433
D+LI GH+DA TIA WKD LNE W++LLEL++TR Q+L+ASR LHKF+HDC+D L RI
Sbjct: 1761 ADSLIATGHSDAATIAEWKDGLNEVWQDLLELIETRTQMLQASRELHKFFHDCKDVLGRI 1820
Query: 5434 MEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALD 5613
+EK +AM D+LGRD+ SV AL RKH N+++D++ + QV QI+ ++A+L+ YAGDKA +
Sbjct: 1821 LEKQNAMSDELGRDAGSVSALQRKHANFMQDLSTLQSQVTQIQEESAKLQASYAGDKARE 1880
Query: 5614 IGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPK 5793
I +RE EVV AW +L+ LCDAR ++L DT DLF+F NMVR L++WMD+V R+MN+ E+P+
Sbjct: 1881 ITNREGEVVAAWNNLQSLCDARRTKLEDTGDLFRFFNMVRTLMIWMDDVVRQMNTSEKPR 1940
Query: 5794 DVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAE 5973
DV+GVELLMNNHQSLKAEIDARE+N ACI+LG+DLL R HYASS+I++KL LT R
Sbjct: 1941 DVAGVELLMNNHQSLKAEIDAREDNLMACINLGKDLLARNHYASSQIKEKLAALTDHRNA 2000
Query: 5974 MMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEA 6153
++ RWE+RWE LQLILEVYQFARDAAVAE+WL AQEPYL+S+E G ++E LIKKHEA
Sbjct: 2001 LLHRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLMSQELGHTIDEVENLIKKHEA 2060
Query: 6154 FEKSAFAQEERFLALEKLTTFELKE----TQHREEETAKRRGPAHIGSPSR-------ST 6300
FEKSA AQEERF AL +LTTFELKE Q REEE +++ A +R ++
Sbjct: 2061 FEKSAAAQEERFSALHRLTTFELKEMKRREQEREEEERRKKEEAAAAEAARLAKATPVTS 2120
Query: 6301 PAAETSFGAQDDGAKQGE 6354
P S A+ +G GE
Sbjct: 2121 PDEPPSERAEAEGVPSGE 2138
Score = 103 bits (258), Expect = 4e-20
Identities = 67/183 (36%), Positives = 92/183 (49%), Gaps = 19/183 (10%)
Frame = +1
Query: 6241 EEETAKRRGPAHIGSPSRS--------TPAAETSFGAQDDGAKQGEA-------FEGTLI 6375
E T +R+ + SP RS +P+ + S G DD E FEG L
Sbjct: 2271 ESGTLRRKERSRSKSPFRSFRWRKSAKSPSLDRS-GVSDDERSISEQRSPTDDEFEGVLQ 2329
Query: 6376 RKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHR----DESVHGEPPMALPGCSVN 6543
RKH +ES +KA+NRSW K+Y V+R L Y D K D+ GE P+ L G ++
Sbjct: 2330 RKHEWESTTKKASNRSWHKVYMVVRGQSLFVYTDQKSYKAAPDQPYKGESPLDLRGATIT 2389
Query: 6544 VASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPAE 6723
VASDY KKK+V ++ G+++LFQ + +M W+T L A SR+ TLPA
Sbjct: 2390 VASDYTKKKHVFRVKSQSGSDFLFQAKDDSEMNEWVTVLNQAAQGTSGAGTSRAHTLPAP 2449
Query: 6724 GSA 6732
A
Sbjct: 2450 TQA 2452
>gi|31201699|ref|XP_309797.1| ENSANGP00000023406 [Anopheles gambiae]
gi|30178366|gb|EAA45309.1| ENSANGP00000023406 [Anopheles gambiae str.
PEST]
Length = 2362
Score = 2414 bits (6257), Expect = 0.0
Identities = 1242/2337 (53%), Positives = 1630/2337 (69%), Gaps = 102/2337 (4%)
Frame = +1
Query: 16 GNSGAYTQDEDYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDL 192
G + +D +YD NSS+RLFERSRIKALA+ERE VQKKTFTKWVNSHLVRV+ ++DL
Sbjct: 15 GPGNEFIEDIEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLVRVNSPIKDL 74
Query: 193 YMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDI 372
Y+DMRDGK L++LL VLSGERLP+PT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDI
Sbjct: 75 YVDMRDGKNLIKLLEVLSGERLPRPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDI 134
Query: 373 VDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNF 552
VDGN+ L LGLIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF
Sbjct: 135 VDGNASLNLGLIWTIILRFQIQDITIEETDNKETKSAKDALLLWCQMKTAGYHNVNVRNF 194
Query: 553 STSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNV 732
+TSWRDGLAFNA+IHKHRPDL+ +D L K+N + NL +AF+ AE +LGL K LDAED+ V
Sbjct: 195 TTSWRDGLAFNAIIHKHRPDLIQFDKLSKTNPIQNLNNAFNVAEEKLGLTKLLDAEDIFV 254
Query: 733 DQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWI 912
D PDEKSIITYVVTYYHYF+KLKQ+ +QGKRIGKV+ M+ND+MIN YE+L+S+LL+WI
Sbjct: 255 DHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMDNDRMINEYESLTSELLKWI 314
Query: 913 NAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQ 1092
I L +RHF N+L GVQ+QL +F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ
Sbjct: 315 EVTIVQLGDRHFVNSLVGVQQQLAQFSNYRTVEKPPKFVEKGNLEVLLFTLQSKMRANNQ 374
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
+P+ P+EGK+I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARFNRKA MRETWL
Sbjct: 375 KPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFNRKATMRETWL 434
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
+ENQRLVS DNFG DL++VEAA KKHEAIETDIFAYEER YHD +
Sbjct: 435 SENQRLVSTDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCNELEAEKYHDIER 494
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I RK+NV ARR+RLE S+ +Q+ F IK RLL++D G
Sbjct: 495 IAARKDNVLRLWNYLIELLRARRMRLEFSIQLQQNFQEMIYILDSMEEIKQRLLTDDYGK 554
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HLM VEDLLQKH+L+E+DIN++G+RV + +Q+F + + YKP +P I +R
Sbjct: 555 HLMGVEDLLQKHSLVEADINVLGDRVKQVVQNSQKFLVDEEDN---YKPCDPSIIVDRVQ 611
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
L+ Y EL LA ER+ RLE+N++L QF+WD+A+ E+ IKE+EQ++S+ + G D+ TV+
Sbjct: 612 RLEDAYAELCKLAVERRSRLEENRKLWQFYWDMADEENWIKEKEQIVSADEIGHDLTTVN 671
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSA 2172
LL+KHK E+ ++ E L + G EL G+D I RL EI + L+EL+
Sbjct: 672 LLLSKHKALESEIQSHEPQLMAVSEVGDELVRRGHFGADRIDERLKEILAMWSNLRELTE 731
Query: 2173 SRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQ 2352
R++RL V+Y+Q F DADD+D ++ D LR++SSEDVG+DE VQ LLKKH DV DEL+
Sbjct: 732 YRRKRLEDAVDYFQLFADADDIDNWMLDALRLVSSEDVGRDEANVQSLLKKHKDVADELK 791
Query: 2353 NFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKL 2532
N+ + I+ LHA+A+ L E + +RL + EL L++LRKQRL+DALSLYKL
Sbjct: 792 NYAETIEQLHAQAKRLTLNEPEQERVNERLAAIDNRYRELMELAKLRKQRLLDALSLYKL 851
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
S++D VE WI EK ++L T+VPG+DIE+VEIMKHR+D +++M ++V VN LARQ
Sbjct: 852 ISESDGVEQWIGEKERMLQTMVPGKDIEDVEIMKHRYDGFDKEMNANASRVAVVNQLARQ 911
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
LL+VEHPNS +I+ RQN LN W++LR+ + KR++L+ AH ++TF I+C+ETV+WIEDK
Sbjct: 912 LLHVEHPNSPEIIERQNHLNNSWSKLREQAESKRDDLKSAHGVQTFYIECRETVSWIEDK 971
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
R+L ++D+L DL+GVM LQRRLS MERDL AIQAKL +L EAD IE + P+EA IR
Sbjct: 972 KRILTETDSLQMDLTGVMTLQRRLSGMERDLAAIQAKLTALENEADAIEGDHPEEAALIR 1031
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
E + I +W+ L + ++E ++KL+EAGDL RFLRDLDHFQAWLT TQ VASE+ P SL
Sbjct: 1032 ERVATIQTIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQAWLTKTQTDVASEDTPTSL 1091
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQT---DPQYMFLRQRLAGLQEGW 3423
EAE+LLNQH +IREEID Y EDYKKM G+ +T + T DPQYMFLR+RL L++GW
Sbjct: 1092 PEAEKLLNQHQSIREEIDNYTEDYKKMMDYGEGLTSEPTQTEDPQYMFLRERLKALKDGW 1151
Query: 3424 EELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRH 3603
EEL +MW+NRQ LLSQGL+ Q+F RDA+QAEV+LSQQE+ L+KDD P +LEQAENQLKRH
Sbjct: 1152 EELHQMWENRQVLLSQGLDQQLFNRDARQAEVLLSQQEHVLSKDDTPVNLEQAENQLKRH 1211
Query: 3604 QDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKL 3783
+ F+TTM+ANDEK + Q+ H+ ADKI K+A +I RR NR +A E+ +KL
Sbjct: 1212 EAFLTTMEANDEKFNTIVQVAGQMTSKDHFDADKITKRAESIAHRRDDNRNRALELHEKL 1271
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLD 3963
K+ + L +FL D +EL EW++EK I AQD+TYR AKT+ SK+ RHQAF++E+AANKERL
Sbjct: 1272 KNQVKLHEFLQDIEELTEWVQEKYITAQDDTYRSAKTVHSKWTRHQAFEAEIAANKERLH 1331
Query: 3964 QLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIAD 4143
+ K AA L +KPE+ I+P++ +L+ +DELE +T+EKG LFDA R+ + QS+ D
Sbjct: 1332 EAKKAAQELMVEKPEFKEIIEPKLTDLSKNFDELETSTKEKGALLFDAKREVIVQQSVDD 1391
Query: 4144 MKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
+ W LE ++ D DLT+VN+ MQKQ +I+T+M KA+ ++ P
Sbjct: 1392 IDSWMDDLEKQIINTDTGNDLTSVNILMQKQQIIQTQMAVKARQVEELDKQTEVLTKTAP 1451
Query: 4324 -DELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
D LE I + AV + ++++APL +R++ LE+KK AFQF RDV+DEKLWI E++ LA+
Sbjct: 1452 SDVLEPIVEKKTAVNARFEKIKAPLLERQRQLEKKKEAFQFRRDVEDEKLWIDEKMPLAE 1511
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
+ G SL + H L+K Q L+ EIDNHEP I ICNNGQ+LIDEGH + ++ I +L
Sbjct: 1512 STEYGNSLFNVHVLKKKHQSLNTEIDNHEPRIMTICNNGQKLIDEGHEDAGSYADLISQL 1571
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
WQELK+AV++R L +SEK Q+ +D EAE+WMSEQELYMM ++RGKDE S +N
Sbjct: 1572 TQKWQELKDAVENRHRQLDQSEKVQQYFFDAAEAESWMSEQELYMMVEDRGKDETSAQNL 1631
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
+KKHE L+ ++ +ADTIR L A + E+ ++Q+ V+Q+Q++KLYAGL+D
Sbjct: 1632 MKKHESLEQSVEDYADTIRQLGETARQLTTEQHAYSDQVSVKQSQLDKLYAGLKDLAGER 1691
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
+ L RE+DDL QWI D+EVVAGS E GQDY+H+ +L ERF +FA+DT +
Sbjct: 1692 RARLDEALQLFMLSREVDDLEQWITDREVVAGSHELGQDYDHITLLWERFNEFAQDTATV 1751
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
GSERVA AN D LI GH+D+ TIA WKD LNE+W++LLEL++TR +L ASR LHKF
Sbjct: 1752 GSERVAKANGIADDLIHAGHSDSATIAEWKDGLNESWQDLLELIETRKAMLAASRELHKF 1811
Query: 5401 YHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
+HDC+D L RI EK H + ++LGRD+ V AL RKHQN+++D+ + QV QI+ ++A+L
Sbjct: 1812 FHDCKDVLGRINEKQHGVSEELGRDAGVVSALQRKHQNFIQDLMTLHSQVQQIQEESAKL 1871
Query: 5581 RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEV 5760
+ YAG+KA +I +RE EV+ AW HL+ +C+ R +L DT DLFKF NMVR L+LWM++V
Sbjct: 1872 QAAYAGEKAREITNREHEVLNAWAHLQSMCEERRGKLADTGDLFKFFNMVRTLMLWMEDV 1931
Query: 5761 KREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEK 5940
R+MN+ E+P+DVSGVELLMNNHQSLKAEID RE+NF+AC++LG++LL+R HYAS++I+
Sbjct: 1932 VRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFSACLALGKELLSRNHYASADIKD 1991
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNL- 6117
+L++LT R ++ RWE+RWE LQLILEVYQFARDAAVAE+WL AQEPYL+S E G +
Sbjct: 1992 RLLQLTNSRNALLHRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLMSTELGHTID 2051
Query: 6118 -------------------EETIKLIKKHEAFE--------KSAFAQEERFLALEKLTTF 6216
EE +++ FE +A E + L E
Sbjct: 2052 EVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKRRQDAAEEAERQRLEAEAAAAR 2111
Query: 6217 ELKETQH---REEETAKRRGPA------------------------HIGSPS-RSTPAAE 6312
E + R++E A R A H G P RS+ +A
Sbjct: 2112 AAAEAEAEAIRQQEAAAARDAADAPGSPHSTREQESVAGETLVSRRHSGVPKERSSSSAS 2171
Query: 6313 TSFGAQ-----------------------DDGAKQGE------------AFEGTLIRKHT 6387
S G + DDGA + A EG L RKH
Sbjct: 2172 ASAGVKVSRRSRSKSPFRSFRWKRTASKADDGAASDDEDRPSPGGADEGAQEGILTRKHE 2231
Query: 6388 YESLDRKAANRSWEKLYAVLRQNELSFYKDPKHR----DESVHGEPPMALPGCSVNVASD 6555
+ES +KA+NRSW+K+Y V R L+F+KD + +++ GEPP+ L G + +ASD
Sbjct: 2232 WESTTKKASNRSWDKVYCVARSGRLTFFKDQRSAKSVPEQTFRGEPPLELKGAQIEIASD 2291
Query: 6556 YQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEA--SRSQTLPA 6720
Y KKK+V ++L G E+L QC + +MQ+W+T L+ Q +L+ + RS TLPA
Sbjct: 2292 YTKKKHVFRIKLSNGGEFLLQCHDDAEMQQWVTALK---AQCELDASGEGRSLTLPA 2345
>gi|4507195|ref|NP_003119.1| spectrin, beta, non-erythrocytic 1
isoform 1; Spectrin, beta, nonerythrocytic-1
(beta-fodrin) [Homo sapiens]
gi|2493434|sp|Q01082|SPCO_HUMAN Spectrin beta chain, brain 1
(Spectrin, non-erythroid beta chain 1) (Beta-II spectrin)
(Fodrin beta chain)
gi|345765|pir||A44159 spectrin beta-G chain - human
gi|338443|gb|AAA60580.1| beta-spectrin
Length = 2364
Score = 2241 bits (5807), Expect = 0.0
Identities = 1157/2304 (50%), Positives = 1552/2304 (67%), Gaps = 74/2304 (3%)
Frame = +1
Query: 43 EDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
+D+D +NSSARLFERSRIKALADERE VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTL
Sbjct: 88 LIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDG+A
Sbjct: 148 GLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN
Sbjct: 268 TYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNN 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ ++PREGK
Sbjct: 328 RKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQ
Sbjct: 388 LISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL +VEAATKKHEAIETDI AYEER NYHD +I RK+NV
Sbjct: 448 DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVI 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
ARR RLE+++ +QKIF +K +LS+D G HL+ VEDLL
Sbjct: 508 RLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I ERV A AQ+F DG GYKP +P I +R ++ Y+EL
Sbjct: 568 QKHTLVEADIGIQAERVRGVNASAQKFAT----DGEGYKPCDPQVIRDRVAHMEFCYQEL 623
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
LAAER+ RLE+++RL +F+W++AE E I+E+E++LSS D G+D+ +V LL+KH+
Sbjct: 624 CQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAF 683
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ + + ++ G+++ E GS+ I R+ IR+ L++LSA RK+RL
Sbjct: 684 EDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEA 743
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
+QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ N+ + L
Sbjct: 744 SLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTL 803
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
H +A +LPQE E PD+R RL ++ E+ L++LRKQ L D L+LYK++S+AD+ E
Sbjct: 804 HEQASALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACEL 863
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
WIDEK + L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++ HP+
Sbjct: 864 WIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSE 923
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
+I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET +WI +KT+V+E +
Sbjct: 924 KEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQD 983
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L NDL+GVM LQR+L+ MERDL AI+AKL L KEA+ +E E P +AQAI + I V
Sbjct: 984 LGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDV 1043
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W+ + ++ EA L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EAE+LL Q
Sbjct: 1044 WEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQ 1103
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
H I+ EID Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL +MW+NRQ+
Sbjct: 1104 HENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQN 1163
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
LLSQ Q FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TTMDAN+E
Sbjct: 1164 LLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEE 1223
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
KI AV G +L DG+ +D+I +K +ID+R NRE A E+L +LKD LQ+FL D
Sbjct: 1224 KINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQD 1283
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA+NKE LD+++ + L +
Sbjct: 1284 CQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISE 1343
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KPE + ++ L W+ LE TT+ K Q+LFDAN+ +L+ QS AD+ +W LE+++
Sbjct: 1344 KPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQI 1403
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D LT+VN+ ++KQ ++E +M + + I+ + + + RL
Sbjct: 1404 QSDDYGKHLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQ-EGKSTDEVDSKRLT 1462
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
VQ + L PL++R+ L K QF RDV+DE LW+ ER+ LA + + G +L
Sbjct: 1463 VQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQL 1522
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKKIQELRSAWQELKEAVK 4716
L K Q L EI H+P I+ I Q ++ D + A +++ +L+ W L E +
Sbjct: 1523 LIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETE 1582
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
R L E+ +A Q+ +D EAEAWMSEQELYMM +E+ KDE S + +KKH+ L+ ++
Sbjct: 1583 KRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVE 1642
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
+A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D +
Sbjct: 1643 DYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQ 1702
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARDT NIG ERV N
Sbjct: 1703 LNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNHLA 1762
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIM 5436
D LI GH+DA TIA WKD LNEAW +LLEL+DTR QIL AS LHKFYHD ++ RI
Sbjct: 1763 DELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQ 1822
Query: 5437 EKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDI 5616
+K +P++LGRD ++V L R H + DI A+G QV Q++ DAA L+ YAGDKA DI
Sbjct: 1823 DKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDI 1882
Query: 5617 GSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKD 5796
RE+EV++AW+ L C++R RL+DT D F+F +MVRDL+LWM++V R++ +QE+P+D
Sbjct: 1883 QKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRD 1942
Query: 5797 VSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEM 5976
VS VELLMNNHQ +KAEIDAR ++F CI LG+ LL RKHYAS EI++KL++LT +R EM
Sbjct: 1943 VSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEM 2002
Query: 5977 MRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G++++E KLIK+HEAF
Sbjct: 2003 IDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAF 2062
Query: 6157 EKSAFAQEERFLALEKLTTFELKETQHRE------------------------------- 6243
EKSA +ERF ALE+LTT EL E + ++
Sbjct: 2063 EKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSTKVSEEAESQQQWDTS 2122
Query: 6244 --EETAKRRGPAHIGSP--SRSTPAAETSFGAQDDGAKQGEA------------------ 6357
E+ ++ PA GSP + + +E GA + E+
Sbjct: 2123 KGEQVSQNGLPAEQGSPRMAETVDTSEMVNGATEQRTSSKESSPIPSPTSDRKAKTALPA 2182
Query: 6358 -----------------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKH 6486
EG L RKH +E+ ++KA++RSW +Y V+ E+ FYKD K
Sbjct: 2183 QSAATLPARTQETPSAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKT 2242
Query: 6487 RDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL 6660
+ H E P++L VA DY+KKK+V LRL G EYLFQ +E+M W+ +
Sbjct: 2243 AASGIPYHSEVPVSLKEAVCEVALDYKKKKHVFKLRLNDGNEYLFQAKDDEEMNTWIQAI 2302
Query: 6661 QVATGQAQLEEASRSQTLPAEGSA 6732
A + E ++ +Q+ PA A
Sbjct: 2303 SSAISSDKHEVSASTQSTPASSRA 2326
>gi|33303722|gb|AAQ02380.1| non-erythroid spectrin beta [Rattus
norvegicus]
Length = 2358
Score = 2214 bits (5737), Expect = 0.0
Identities = 1164/2315 (50%), Positives = 1541/2315 (66%), Gaps = 85/2315 (3%)
Frame = +1
Query: 43 EDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
+D+D +NSSARLFERSRIKALADERE VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTL
Sbjct: 88 LIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDG+A
Sbjct: 148 GLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN
Sbjct: 268 TYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNN 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ ++PREGK
Sbjct: 328 RKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQ
Sbjct: 388 LISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL +VEAATKKHEAIETDI AYEER +YHD +I RK+NV
Sbjct: 448 DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAESYHDIKRITARKDNVI 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
ARR RLE+++ +QKIF +K LLS+D G HL+ VEDLL
Sbjct: 508 RLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKHAL+E+DI I ERV A AQ+F DG GYKP +P I +R ++ Y+EL
Sbjct: 568 QKHALVEADIAIQAERVRGVNASAQKFAT----DGEGYKPCDPQVIRDRVAHMEFCYQEL 623
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
LAAER+ RLE+++RL +F+W++AE E I+E+E++LSS D G+D+ +V LL+KH+
Sbjct: 624 CQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAF 683
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ + + ++ G+++ E GS+ I R++ IR+ L++LSA RK+RL
Sbjct: 684 EDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERISYIREQWANLEQLSAIRKKRLEEA 743
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
+QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ N+ I L
Sbjct: 744 SLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEISNYRPTIDTL 803
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
H +A +LPQ E PD++ RL ++ E+ L++LRKQ L D L+LYK++S+AD+ E
Sbjct: 804 HEQAGALPQAHAESPDVKGRLAGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACEL 863
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
WIDEK + L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++ HP+
Sbjct: 864 WIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSE 923
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
+I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET +WI +KT+V+E +
Sbjct: 924 KEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQD 983
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L NDL+GVM LQR+L+ MERDL AI+AKL L KEA+ +E E P +AQAI + I V
Sbjct: 984 LGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDV 1043
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W+ + ++ EA L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EAE+LL Q
Sbjct: 1044 WEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQ 1103
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
H I+ EID Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL +MW+NRQ+
Sbjct: 1104 HENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQN 1163
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
LLSQ Q FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TTMDAN+E
Sbjct: 1164 LLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEE 1223
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
KI AV G +L DG+ +D+I +K +ID+R NRE A E+L +LKD LQ+FL D
Sbjct: 1224 KINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQD 1283
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA+NKE LD+++ + L +
Sbjct: 1284 CQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISE 1343
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KPE + ++ L W+ LE TT+ K Q+LFDAN+ +L+ QS AD+ +W LE+++
Sbjct: 1344 KPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQI 1403
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIK----- 4344
+D DLTT AQ+ P I+
Sbjct: 1404 QSDDYGKDLTT-----------------SAQNKVLDGASVFLLMYSCPPRCWRIRWKRGR 1446
Query: 4345 ------AHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQ 4506
+ RL VQ + L PL++R+ L K QF RDV+DE LW+ ER+ LA +
Sbjct: 1447 AQMRVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATST 1506
Query: 4507 NLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKKIQELR 4683
+ G +L L K Q L EI H+P I+ I Q +I D N A +++ +L+
Sbjct: 1507 DHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLK 1566
Query: 4684 SAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQI 4863
W L E + R L E+ KA Q+ +D EAEAWMSEQELYMM +E+ KDE S + +
Sbjct: 1567 QLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSML 1626
Query: 4864 KKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXX 5043
KKH+ L+ ++ +A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D
Sbjct: 1627 KKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERR 1686
Query: 5044 XXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIG 5223
+ L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARDT NIG
Sbjct: 1687 GKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIG 1746
Query: 5224 SERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFY 5403
ERV N D LI GH+DA TIA WKD LNEAW +LLEL+DTR QIL AS LHKFY
Sbjct: 1747 QERVDTVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFY 1806
Query: 5404 HDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELR 5583
HD ++ RI +K +P++LGRD ++V L R H + DI A+G QV Q++ DAA L+
Sbjct: 1807 HDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQ 1866
Query: 5584 DGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVK 5763
YAGDKA DI RE+EV++AW+ L C+ R RL+DT D F+F +MVRDL+LWM++V
Sbjct: 1867 AAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVI 1926
Query: 5764 REMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKK 5943
R++ +QE+P+DVS VELLMNNHQ +KAEIDAR ++F ACI LG+ LL RKHYAS EI++K
Sbjct: 1927 RQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKALLARKHYASEEIKEK 1986
Query: 5944 LIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEE 6123
L++LT +R EM+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G++++E
Sbjct: 1987 LLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDE 2046
Query: 6124 TIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKET---QHREE---------------- 6246
KLIK+HEAFEKSA +ERF ALE+LTT EL E Q EE
Sbjct: 2047 VEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSAKVSE 2106
Query: 6247 -------------ETAKRRGPAHIGSPSRSTPAAETSF---GAQDDGAKQGEA------- 6357
+ ++ PA GSP R ETS GA + E+
Sbjct: 2107 EAESQQWDTSKGDQVSQNGLPAEQGSP-RMAGTMETSEMVNGAAEQRTSSKESSPVPSPT 2165
Query: 6358 ----------------------------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQ 6453
EG L RKH +E+ ++KA++RSW +Y V+
Sbjct: 2166 SDRKAKSALPAQSAATLPARTLETPAAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINN 2225
Query: 6454 NELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGS 6627
E+ FYKD K V H E P++L VA DY+KKK+V LRL G EYLFQ
Sbjct: 2226 QEMGFYKDAKSAASGVPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKD 2285
Query: 6628 EEDMQRWLTELQVATGQAQLEEASRSQTLPAEGSA 6732
+++M W+ + A + + ++ +Q+ PA A
Sbjct: 2286 DDEMNTWIQAITSAISSDKHDTSASTQSTPASSRA 2320
>gi|30348966|ref|NP_787030.1| spectrin beta 2 isoform 1; beta-spectrin
2, non-erythrocytic; beta fodrin; spectrin G; brain
spectrin; non-erythrocytic [Mus musculus]
gi|2493435|sp|Q62261|SPCO_MOUSE Spectrin beta chain, brain 1
(Spectrin, non-erythroid beta chain 1) (Beta-II spectrin)
(Fodrin beta chain)
gi|409226|gb|AAC42040.1| brain beta spectrin [Mus musculus]
Length = 2363
Score = 2206 bits (5715), Expect = 0.0
Identities = 1159/2305 (50%), Positives = 1536/2305 (66%), Gaps = 75/2305 (3%)
Frame = +1
Query: 43 EDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
+D+D +NSSARLFERSRIKALADERE VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTL
Sbjct: 88 LIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDG+A
Sbjct: 148 GLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN
Sbjct: 268 TYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNN 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ ++PREGK
Sbjct: 328 RKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQ
Sbjct: 388 LISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL +VEAATKKHEAIETDI AYEER NYHD +I RK+NV
Sbjct: 448 DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVI 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
ARR RLE+++ +QKIF +K LLS+D G HL+ VEDLL
Sbjct: 508 RLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKHAL+E+DI I ERV A AQ+F DG GYKP +P I +R ++ Y+EL
Sbjct: 568 QKHALVEADIAIQAERVRGVNASAQKFAT----DGEGYKPCDPQVIRDRVAHMEFCYQEL 623
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
LAAER+ RLE+++RL +F+W++AE E I+E+E++LSS D G+D+ +V LL+KH+
Sbjct: 624 CQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAF 683
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ + + ++ G+++ E GS+ I R+ IR+ L++LSA R +RL
Sbjct: 684 EDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRIKRLEEA 743
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
+QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ N+ I L
Sbjct: 744 SLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTL 803
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
H +A +LPQ E PD++ RL ++ E+ L++LRKQ L D L+LYK++S+AD+ E
Sbjct: 804 HEQASALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALRDTLALYKMFSEADACEL 863
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
WIDEK + L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++ HP+
Sbjct: 864 WIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSE 923
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
+I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET +WI +KT+V+E +
Sbjct: 924 KEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQD 983
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L NDL+GVM LQR+L+ MERDL AI+AKL L KEA+ +E E P +AQAI + I V
Sbjct: 984 LGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDV 1043
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W+ + ++ EA L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EAE+LL Q
Sbjct: 1044 WEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQ 1103
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
H I+ EID Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL +MW+NRQ+
Sbjct: 1104 HENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQN 1163
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
LLSQ Q FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TTMDAN+E
Sbjct: 1164 LLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEE 1223
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
KI AV G +L DG+ +D+I +K +ID+R NRE A E+L +LKD LQ+FL D
Sbjct: 1224 KINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQD 1283
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA+NKE LD+++ + L +
Sbjct: 1284 CQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISE 1343
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KPE + ++ L W+ LE TT+ K Q+LFDAN+ +L+ QS AD+ +W LE
Sbjct: 1344 KPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLEKPG 1403
Query: 4180 TREDQPG-DLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ D G DLT + +K + K + + + RL
Sbjct: 1404 FQSDDYGKDLTQSQYSSEKGNRRRRIRWKFGRKRSRNCRPSPGSSRGRAQM--RVDSKRL 1461
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
VQ + L PL +R+ L K QF RDV+DE LW+ ER+ L + + G +L
Sbjct: 1462 TVQTKFMELLEPLSERKHNLLASKEIHQFNRDVEDEILWVGERMPLRTSTDHGHNLQTVQ 1521
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKKIQELRSAWQELKEAV 4713
L K Q L EI H+P I+ I Q +I D N A +++ +L+ W L E
Sbjct: 1522 LLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEET 1581
Query: 4714 KDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDI 4893
+ R L E+ KA Q+ +D EAEAWMSEQELYMM ++R + + S + +KKH+ L+ +
Sbjct: 1582 EKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEKRPRMKQSAVSMLKKHQILEQAV 1641
Query: 4894 DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXY 5073
+ +A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D +
Sbjct: 1642 EDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLF 1701
Query: 5074 ALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDG 5253
L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARDT NIG ERV N+
Sbjct: 1702 QLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNM 1761
Query: 5254 CDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRI 5433
D LI GH+DA TIA WKD LNEAW +LLEL+DTR QIL AS LHKFYHD ++ RI
Sbjct: 1762 ADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRI 1821
Query: 5434 MEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALD 5613
+K +P++LGRD ++V L R H + DI A+G QV Q++ DAA L+ YAGDKA D
Sbjct: 1822 QDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADD 1881
Query: 5614 IGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPK 5793
I RE+EV++AW+ L G C+ R RL+DT D F+F +MVRDL+LWM++V R++ +QE+P+
Sbjct: 1882 IQKRENEVLEAWKSLLGACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPR 1941
Query: 5794 DVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAE 5973
DVS VELLMNNHQ +KAEIDAR ++F ACI LG+ LL RKHYAS EI++KL++LT +R E
Sbjct: 1942 DVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKE 2001
Query: 5974 MMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEA 6153
M+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G++++E KLIK+HEA
Sbjct: 2002 MIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEA 2061
Query: 6154 FEKSAFAQEERFLALEKLTTFELKET---QHREE-------------------------- 6246
FEKSA +ERF ALE+LTT EL E Q EE
Sbjct: 2062 FEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPDPNTKVSEEAESQQWDTS 2121
Query: 6247 ---ETAKRRGPAHIGSPSRSTPAAETSF---GAQDDGAKQGEA----------------- 6357
+ ++ PA GSP R ETS GA + E+
Sbjct: 2122 KGDQVSQNGLPAEQGSP-RMAGTMETSEMVNGAAEQRTSSKESSPVPSPTSDRKAKSALP 2180
Query: 6358 ------------------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPK 6483
EG L RKH +E+ ++KA++RSW +Y V+ E+ FYKD K
Sbjct: 2181 AQSAATLPARTLETPAAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAK 2240
Query: 6484 HRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTE 6657
+ H E P++L VA DY+KKK+V LRL G EYLFQ +E+M W+
Sbjct: 2241 SAASGIPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQA 2300
Query: 6658 LQVATGQAQLEEASRSQTLPAEGSA 6732
+ A + + ++ +Q+ PA A
Sbjct: 2301 ISSAISSDKHDTSASTQSTPASSRA 2325
>gi|34879632|ref|XP_240072.2| similar to Spectrin beta chain, brain 1
(Spectrin, non-erythroid beta chain 1) (Beta-II spectrin)
(Fodrin beta chain) [Rattus norvegicus]
Length = 2407
Score = 2196 bits (5690), Expect = 0.0
Identities = 1150/2320 (49%), Positives = 1534/2320 (65%), Gaps = 109/2320 (4%)
Frame = +1
Query: 100 LADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGK 279
LADERE VQKKTFTKWVNSHL RVSC++ DLY D+RDG+ML++LL VLSGERLPKPT G+
Sbjct: 56 LADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGR 115
Query: 280 MRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDA 459
MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGLIWTIILRFQIQDI+ E
Sbjct: 116 MRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETE 175
Query: 460 DNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQK 639
DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDG+AFNALIHKHRPDL+D+D L+K
Sbjct: 176 DNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKK 235
Query: 640 SNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQG 819
SNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSIITYVVTYYHYF+K+K ++G
Sbjct: 236 SNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEG 295
Query: 820 KRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDY 999
KRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN R F N+L GVQ+QL FN Y
Sbjct: 296 KRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTY 355
Query: 1000 RTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERE 1179
RT EKPPKF EKG LEVLLFT+QS MRANNQ+ ++PREGKLI+DIN+AW+ LEKAEHERE
Sbjct: 356 RTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERE 415
Query: 1180 LVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAI 1359
L L+ ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQDNFG DL +VEAATKKHEAI
Sbjct: 416 LALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAI 475
Query: 1360 ETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELS 1539
ETDI AYEER +YHD +I RK+NV ARR RLE++
Sbjct: 476 ETDIAAYEERVQAVVAVARELEAESYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMN 535
Query: 1540 MAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNS 1719
+ +QKIF +K LLS+D G HL+ VEDLLQKHAL+E+DI I ERV
Sbjct: 536 LGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLLQKHALVEADIAIQAERVRGV 595
Query: 1720 IAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQF 1899
A AQ+F DG GYKP +P I +R ++ Y+EL LAAER+ RLE+++RL +F
Sbjct: 596 NASAQKFAT----DGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKF 651
Query: 1900 WWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKE 2079
+W++AE E I+E+E++LSS D G+D+ +V LL+KH+ E+ + + ++ G++
Sbjct: 652 FWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGED 711
Query: 2080 LQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDT 2259
+ E GS+ I R++ IR+ L++LSA RK+RL +QF DADD+D ++ D
Sbjct: 712 MIAEEHFGSEKIRERISYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDI 771
Query: 2260 LRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQR 2439
L+++SS DVG DE + Q L+KKH DV +E+ N+ I LH +A +LPQ E PD++ R
Sbjct: 772 LKIVSSNDVGHDEYSTQSLVKKHKDVAEEISNYRPTIDTLHEQAGALPQAHAESPDVKGR 831
Query: 2440 LDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEE 2619
L ++ E+ L++LRKQ L D L+LYK++S+AD+ E WIDEK + L + +E+
Sbjct: 832 LAGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLED 891
Query: 2620 VEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDM 2799
+E+++HRF++LE +M NQ ++V VN +ARQL++ HP+ +I +Q+KLN RW+Q R++
Sbjct: 892 LEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIRAQQDKLNTRWSQFREL 951
Query: 2800 VDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMER 2979
VD+K++ L A ++ + ++C ET +WI +KT+V+E + L NDL+GVM LQR+L+ MER
Sbjct: 952 VDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMER 1011
Query: 2980 DLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGD 3159
DL AI+AKL L KEA+ +E E P +AQAI + I VW+ + ++ EA L EA
Sbjct: 1012 DLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASK 1071
Query: 3160 LQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRA 3339
LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EAE+LL QH I+ EID Y EDY+KMR
Sbjct: 1072 LQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRD 1131
Query: 3340 MGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEV 3519
MG+ VTQ QTD QYMFLRQRL L GW EL +MW+NRQ+LLSQ Q FLRD KQAE
Sbjct: 1132 MGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEA 1191
Query: 3520 MLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAA 3699
L+ QE LA ++P +LE AE +K+ +DF+TTMDAN+EKI AV G +L DG+ +
Sbjct: 1192 FLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINS 1251
Query: 3700 DKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY 3879
D+I +K +ID+R NRE A E+L +LKD LQ+FL DC EL WI EKM+ AQD +Y
Sbjct: 1252 DRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSY 1311
Query: 3880 RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWD 4059
+A+ + SK+++HQAF +ELA+NKE LD+++ + L +KPE + ++ L W+
Sbjct: 1312 DEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWE 1371
Query: 4060 ELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQH 4239
LE TT+ K Q+LFDAN+ +L+ QS AD+ +W LE+++ +D DLT+VN+ ++KQ
Sbjct: 1372 VLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQ 1431
Query: 4240 ------------------------------------LIETEMIKKAQHIDXXXXXXXXXX 4311
++E +M + + I+
Sbjct: 1432 ASGQDRILDLVVSSSSLQIQSLCLSSSMRRDFATREMLENQMEVRKKEIEELQSQAQALS 1491
Query: 4312 XXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLV 4491
+ + + RL VQ + L PL++R+ L K QF RDV+DE LW+ ER+
Sbjct: 1492 Q-EGKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMP 1550
Query: 4492 LAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKK 4668
LA + + G +L L K Q L EI H+P I+ I Q +I D N A ++
Sbjct: 1551 LATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQR 1610
Query: 4669 IQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFS 4848
+ +L+ W L E + R L E+ KA Q+ +D EAEAWMSEQELYMM +E+ KDE S
Sbjct: 1611 LADLKQLWGLLIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQS 1670
Query: 4849 TKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDX 5028
+ +KKH+ L+ ++ +A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D
Sbjct: 1671 AVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDL 1730
Query: 5029 XXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARD 5208
+ L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARD
Sbjct: 1731 AEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARD 1790
Query: 5209 TENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRL 5388
T NIG ERV N D LI GH+DA TIA WKD LNEAW +LLEL+DTR QIL AS
Sbjct: 1791 TGNIGQERVDTVNHMADDLINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYE 1850
Query: 5389 LHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERD 5568
LHKFYHD ++ RI +K +P++LGRD ++V L R H + DI A+G QV Q++ D
Sbjct: 1851 LHKFYHDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQED 1910
Query: 5569 AAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLW 5748
AA L+ YAGDKA DI RE+EV++AW+ L C+ R RL+DT D F+F +MVRDL+LW
Sbjct: 1911 AARLQAAYAGDKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLW 1970
Query: 5749 MDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASS 5928
M++V R++ +QE+P+DVS VELLMNNHQ +KAEIDAR ++F ACI LG+ LL RKHYAS
Sbjct: 1971 MEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKALLARKHYASE 2030
Query: 5929 EIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYG 6108
EI++KL++LT +R EM+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G
Sbjct: 2031 EIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIG 2090
Query: 6109 RNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKET---QHREE----------- 6246
++++E KLIK+HEAFEKSA +ERF ALE+LTT EL E Q EE
Sbjct: 2091 QSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPS 2150
Query: 6247 ------------------ETAKRRGPAHIGSPSRSTPAAETSF---GAQDDGAKQGEA-- 6357
+ ++ PA GSP R ETS GA + E+
Sbjct: 2151 AKVSEEAESQQWDTSKGDQVSQNGLPAEQGSP-RMAGTMETSEMVNGAAEQRTSSKESSP 2209
Query: 6358 ---------------------------------FEGTLIRKHTYESLDRKAANRSWEKLY 6438
EG L RKH +E+ ++KA++RSW +Y
Sbjct: 2210 VPSPTSDRKAKSALPAQSAATLPARTLETPAAQMEGFLNRKHEWEAHNKKASSRSWHNVY 2269
Query: 6439 AVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYL 6612
V+ E+ FYKD K V H E P++L VA DY+KKK+V LRL G EYL
Sbjct: 2270 CVINNQEMGFYKDAKSAASGVPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYL 2329
Query: 6613 FQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLPAEGSA 6732
FQ +++M W+ + A + + ++ +Q+ PA A
Sbjct: 2330 FQAKDDDEMNTWIQAITSAISSDKHDTSASTQSTPASSRA 2369
>gi|50738496|ref|XP_419291.1| PREDICTED: similar to Spectrin beta
chain, brain 1 (Spectrin, non-erythroid beta chain 1)
(Beta-II spectrin) (Fodrin beta chain) [Gallus gallus]
Length = 2399
Score = 2171 bits (5626), Expect = 0.0
Identities = 1113/2142 (51%), Positives = 1484/2142 (68%), Gaps = 38/2142 (1%)
Frame = +1
Query: 43 EDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
+D+D +NSSARLFERSRIKALADERE VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTL
Sbjct: 88 LIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDG+A
Sbjct: 148 GLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN
Sbjct: 268 TYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNN 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ ++PREGK
Sbjct: 328 RKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQ
Sbjct: 388 LISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL +VEAATKKHEAIETDI AYEER NYHD +I RK+NV
Sbjct: 448 DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVAKELETENYHDIKRITARKDNVI 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
ARR RLE+++ +QKIF +K LLS+D G HL+ VEDLL
Sbjct: 508 RLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKHAL+E+DI I ERV A AQ+F DG GYKP +P I +R ++ Y+EL
Sbjct: 568 QKHALVEADIAIQAERVRGVNASAQKF----ATDGEGYKPCDPQVIRDRVAHMEFCYQEL 623
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
L+AER+ RLE+++RL +F+W++AE E I+E+EQ+LSS D G+D+ +V L++KHK
Sbjct: 624 CQLSAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSDDYGKDLTSVVRLMSKHKAF 683
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ + + + G+++ E GS+ I R+ +IR+ L++LSA RK+RL
Sbjct: 684 EDEMSGRSGHFQQAIKEGEDMIAEENFGSEKIRERIKDIREQWANLEQLSAIRKKRLEEA 743
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
+QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ ++ I L
Sbjct: 744 SLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEIASYRPTIDSL 803
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
H +A++LPQE PD++ RL ++ E+ L++LRKQ L D L+LYK++S+AD+ E
Sbjct: 804 HEQAKALPQEHAGSPDVQGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACEL 863
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
WIDEK K L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++ HP+
Sbjct: 864 WIDEKEKWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSE 923
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
+I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET +WI +KT+V+E +
Sbjct: 924 KEIKAQQDKLNTRWSQFRELVDRKKDALISALSIQNYHLECNETKSWIREKTKVIESTQD 983
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L NDL+GVM LQR+L+ MERDL AI+AKL L KEA+ +E E P +AQAI + I+ V
Sbjct: 984 LGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEINDV 1043
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W+ + ++ E L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EAE+LL Q
Sbjct: 1044 WEEMKTTLKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQ 1103
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
H I+ EI+ Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL +MW+NRQ+
Sbjct: 1104 HENIKNEINNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQN 1163
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
LLSQ Q+FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TTMDAN+E
Sbjct: 1164 LLSQSHAYQLFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEE 1223
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGA-----------------------N 3750
KI AV G +L DG+ +DKI +K +ID+R A N
Sbjct: 1224 KINAVVETGRRLVSDGNINSDKIQEKVDSIDDRDAAVLVAFGRAAVWAILQPHCAQHRKN 1283
Query: 3751 REKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQ 3930
RE A E+L +LKD LQ+FL DC EL WI EKM+ AQD +Y +A+ + SK+++HQAF
Sbjct: 1284 REAASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFM 1343
Query: 3931 SELAANKERLDQLK--------HA------AINLGDDKPEYHGTIDPQIEELATQWDELE 4068
+ELA+NKE L++++ HA + L +KPE + ++ L W+ELE
Sbjct: 1344 AELASNKEWLEKIEKEFQAAFSHANLMSEEGMQLIAEKPETEAVVKEKLTGLHQMWEELE 1403
Query: 4069 KTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIE 4248
TT+ K Q+LFDAN+ +L+ QS AD+ +W LE+++ +D DLT+VN+ ++KQ ++E
Sbjct: 1404 STTQTKAQRLFDANKAELFTQSCADLDKWLNGLESQIQSDDYGKDLTSVNILLKKQQMLE 1463
Query: 4249 TEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKK 4428
+M + + I+ + + RL V+++ L PL++R+ L K
Sbjct: 1464 NQMDVRKKEIE-ELQSQARALSQEGKSTDEVDGKRLTVEKKFLELLEPLNERKANLLASK 1522
Query: 4429 AAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQIC 4608
QF RDV+DE LW+ ER+ +A + + G +L L K Q L EI H+P I+ I
Sbjct: 1523 EIHQFNRDVEDEILWVGERMPIATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIF 1582
Query: 4609 NNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEA 4788
Q +I + N A ++++ +L+ W L E + R L ES +A Q+ +D EAEA
Sbjct: 1583 ERSQNIITDSSPNAEAIQQRLADLKQLWNLLIEETEKRHKRLEESHRAQQYYFDAAEAEA 1642
Query: 4789 WMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLT 4968
WMSEQELYMM +E+ KDE S + +KKH+ L+ ++ +A+T+ L+ + V + P +
Sbjct: 1643 WMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRTLVADNHPES 1702
Query: 4969 EQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQEN 5148
E+I +RQ++++KLYAGL+D + L+RE+DDL QWIA++EVVAGS E
Sbjct: 1703 ERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHEL 1762
Query: 5149 GQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEA 5328
GQDYEHV MLQERF++FARDT NIG ERV N D LI GH+DA TIA WKD LNEA
Sbjct: 1763 GQDYEHVTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEA 1822
Query: 5329 WENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKH 5508
W +LLEL+DTR QIL AS LHKFYHD ++ L RI +K +P++LGRD ++V L R H
Sbjct: 1823 WADLLELIDTRTQILAASYELHKFYHDAKEILGRIQDKHKKLPEELGRDQNTVETLQRMH 1882
Query: 5509 QNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSR 5688
+ DI A+G QV Q++ DAA L+ YAGDKA DI RE+EV++AW+ L C+ R R
Sbjct: 1883 TTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKALLDACEGRRVR 1942
Query: 5689 LMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREEN 5868
L+DT D F+F +MVRDL+LWM++V R++ +QE+P+DVS VELLMNNHQ +KAEIDAR ++
Sbjct: 1943 LVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDS 2002
Query: 5869 FNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDA 6048
F CI LG+ LL RKHYAS EI++KL++LT +R EM+ +WEDRWE+L+LILEV+QF+RDA
Sbjct: 2003 FTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDA 2062
Query: 6049 AVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKE 6228
+VAE+WL QEPYL S+E G++++E KLIK+HEAFEKSA +ERF ALE+LTT EL E
Sbjct: 2063 SVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFAALERLTTLELLE 2122
Query: 6229 TQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGE 6354
+ ++EE ++R P +P S AE Q +GE
Sbjct: 2123 VRRQQEEEERKRKPP---TPEPSPKVAEDGGSQQQWDGTKGE 2161
>gi|30315658|ref|NP_842565.1| spectrin, beta, non-erythrocytic 1
isoform 2; Spectrin, beta, nonerythrocytic-1
(beta-fodrin) [Homo sapiens]
gi|27462180|gb|AAO15362.1| beta-spectrin 2 isoform 2 [Homo sapiens]
Length = 2155
Score = 2162 bits (5603), Expect = 0.0
Identities = 1100/2112 (52%), Positives = 1467/2112 (69%), Gaps = 1/2112 (0%)
Frame = +1
Query: 22 SGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMD 201
S AYT Y+ N R K L DERE VQKKTFTKWVNSHL RVSC++ DLY D
Sbjct: 14 SPAYTGQVPYNYNQL-----EGRFKQLQDEREAVQKKTFTKWVNSHLARVSCRITDLYTD 68
Query: 202 MRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDG 381
+RDG+ML++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDG
Sbjct: 69 LRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDG 128
Query: 382 NSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTS 561
N RLTLGLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TS
Sbjct: 129 NHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTS 188
Query: 562 WRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQP 741
WRDG+AFNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD P
Sbjct: 189 WRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHP 248
Query: 742 DEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAK 921
DEKSIITYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI
Sbjct: 249 DEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQT 308
Query: 922 IQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPF 1101
I +LN R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ +
Sbjct: 309 IIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVY 368
Query: 1102 VPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTEN 1281
+PREGKLI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+EN
Sbjct: 369 MPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSEN 428
Query: 1282 QRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINE 1461
QRLVSQDNFG DL +VEAATKKHEAIETDI AYEER NYHD +I
Sbjct: 429 QRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITA 488
Query: 1462 RKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLM 1641
RK+NV ARR RLE+++ +QKIF +K +LS+D G HL+
Sbjct: 489 RKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLL 548
Query: 1642 DVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQ 1821
VEDLLQKH L+E+DI I ERV A AQ+F DG GYKP +P I +R ++
Sbjct: 549 GVEDLLQKHTLVEADIGIQAERVRGVNASAQKFAT----DGEGYKPCDPQVIRDRVAHME 604
Query: 1822 KRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLL 2001
Y+EL LAAER+ RLE+++RL +F+W++AE E I+E+E++LSS D G+D+ +V LL
Sbjct: 605 FCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLL 664
Query: 2002 AKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRK 2181
+KH+ E+ + + ++ G+++ E GS+ I R+ IR+ L++LSA RK
Sbjct: 665 SKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRK 724
Query: 2182 ERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFD 2361
+RL +QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ N+
Sbjct: 725 KRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYR 784
Query: 2362 QHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSD 2541
+ LH +A +LPQE E PD+R RL ++ E+ L++LRKQ L D L+LYK++S+
Sbjct: 785 PTLDTLHEQASALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSE 844
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLN 2721
AD+ E WIDEK + L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++
Sbjct: 845 ADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMH 904
Query: 2722 VEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRV 2901
HP+ +I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET +WI +KT+V
Sbjct: 905 SGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKV 964
Query: 2902 LEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDI 3081
+E + L NDL+GVM LQR+L+ MERDL AI+AKL L KEA+ +E E P +AQAI +
Sbjct: 965 IESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRL 1024
Query: 3082 KRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEA 3261
I VW+ + ++ EA L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EA
Sbjct: 1025 AEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEA 1084
Query: 3262 EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRM 3441
E+LL QH I+ EID Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL +M
Sbjct: 1085 EKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKM 1144
Query: 3442 WDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITT 3621
W+NRQ+LLSQ Q FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TT
Sbjct: 1145 WENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTT 1204
Query: 3622 MDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSL 3801
MDAN+EKI AV G +L DG+ +D+I +K +ID+R NRE A E+L +LKD L
Sbjct: 1205 MDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDL 1264
Query: 3802 QQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAA 3981
Q+FL DC EL WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA+NKE LD+++
Sbjct: 1265 QKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEG 1324
Query: 3982 INLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWAT 4161
+ L +KPE + ++ L W+ LE TT+ K Q+LFDAN+ +L+ QS AD+ +W
Sbjct: 1325 MQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLH 1384
Query: 4162 QLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENI 4341
LE+++ +D LT+VN+ ++KQ ++E +M + + I+ + +
Sbjct: 1385 GLESQIQSDDYGKHLTSVNILLKKQQMLENQMEVRKKEIE-ELQSQAQALSQEGKSTDEV 1443
Query: 4342 KAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGES 4521
+ RL VQ + L PL++R+ L K QF RDV+DE LW+ ER+ LA + + G +
Sbjct: 1444 DSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHN 1503
Query: 4522 LPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKKIQELRSAWQE 4698
L L K Q L EI H+P I+ I Q ++ D + A +++ +L+ W
Sbjct: 1504 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGL 1563
Query: 4699 LKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHER 4878
L E + R L E+ +A Q+ +D EAEAWMSEQELYMM +E+ KDE S + +KKH+
Sbjct: 1564 LIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQI 1623
Query: 4879 LQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXX 5058
L+ ++ +A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D
Sbjct: 1624 LEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDE 1683
Query: 5059 XXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVA 5238
+ L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARDT NIG ERV
Sbjct: 1684 RHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVD 1743
Query: 5239 NANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
N D LI GH+DA TIA WKD LNEAW +LLEL+DTR QIL AS LHKFYHD ++
Sbjct: 1744 TVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKE 1803
Query: 5419 CLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAG 5598
RI +K +P++LGRD ++V L R H + DI A+G QV Q++ DAA L+ YAG
Sbjct: 1804 IFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAG 1863
Query: 5599 DKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNS 5778
DKA DI RE+EV++AW+ L C++R RL+DT D F+F +MVRDL+LWM++V R++ +
Sbjct: 1864 DKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEA 1923
Query: 5779 QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT 5958
QE+P+DVS VELLMNNHQ +KAEIDAR ++F CI LG+ LL RKHYAS EI++KL++LT
Sbjct: 1924 QEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLT 1983
Query: 5959 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
+R EM+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G++++E KLI
Sbjct: 1984 EKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLI 2043
Query: 6139 KKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETS 6318
K+HEAFEKSA +ERF ALE+LTT EL E + ++EE ++R P SP ST +E +
Sbjct: 2044 KRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPP---SPEPSTKVSEEA 2100
Query: 6319 FGAQDDGAKQGE 6354
Q +GE
Sbjct: 2101 ESQQQWDTSKGE 2112
>gi|7106421|ref|NP_033286.1| spectrin beta 2 isoform 2; beta-spectrin
2, non-erythrocytic; beta fodrin; spectrin G; brain
spectrin; non-erythrocytic [Mus musculus]
gi|4102883|gb|AAD01616.1| non-erythrocyte beta spectrin [Mus
musculus]
Length = 2154
Score = 2159 bits (5594), Expect = 0.0
Identities = 1111/2151 (51%), Positives = 1478/2151 (68%), Gaps = 16/2151 (0%)
Frame = +1
Query: 22 SGAYTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMD 201
S AYT Y+ N R K L DERE VQKKTFTKWVNSHL RVSC++ DLY D
Sbjct: 14 SPAYTGQVPYNYNQL-----EGRFKQLQDEREAVQKKTFTKWVNSHLARVSCRITDLYTD 68
Query: 202 MRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDG 381
+RDG+ML++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDG
Sbjct: 69 LRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDG 128
Query: 382 NSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTS 561
N RLTLGLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TS
Sbjct: 129 NHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTS 188
Query: 562 WRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQP 741
WRDG+AFNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD P
Sbjct: 189 WRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHP 248
Query: 742 DEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAK 921
DEKSIITYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YETL+SDLLEWI
Sbjct: 249 DEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYETLASDLLEWIEQT 308
Query: 922 IQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPF 1101
I +LN R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLF +QS MRANNQ+ +
Sbjct: 309 IIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFAIQSKMRANNQKVY 368
Query: 1102 VPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTEN 1281
+PREGKLI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+EN
Sbjct: 369 MPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSEN 428
Query: 1282 QRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINE 1461
QRLVSQDNFG DL +VEAATKKHEAIETDI AYEER NYHD +I
Sbjct: 429 QRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITA 488
Query: 1462 RKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLM 1641
RK+NV ARR RLE+++ +QKIF +K LLS+D G HL+
Sbjct: 489 RKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLL 548
Query: 1642 DVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQ 1821
VEDLLQKHAL+E+DI I ERV A AQ+F DG GYKP +P I +R ++
Sbjct: 549 GVEDLLQKHALVEADIAIQAERVRGVNASAQKFAT----DGEGYKPCDPQVIRDRVAHME 604
Query: 1822 KRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLL 2001
Y+EL LAAER+ RLE+++RL +F+W++AE E I+E+E++LSS D G+D+ +V LL
Sbjct: 605 FCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLL 664
Query: 2002 AKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRK 2181
+KH+ E+ + + ++ G+++ E GS+ I R+ IR+ L++LSA RK
Sbjct: 665 SKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRK 724
Query: 2182 ERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFD 2361
+RL +QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ N
Sbjct: 725 KRLEEASLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNCR 784
Query: 2362 QHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSD 2541
I LH +A +LPQ E PD++ RL ++ E+ L++LRKQ L D L+LYK++S+
Sbjct: 785 PTIDTLHEQASALPQAHAESPDVKGRLAGIEERCKEMAELTRLRKQALQDTLALYKMFSE 844
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLN 2721
AD+ E WIDEK + L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++
Sbjct: 845 ADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMH 904
Query: 2722 VEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRV 2901
HP+ +I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET + I +KT+V
Sbjct: 905 NGHPSEKEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSCIREKTKV 964
Query: 2902 LEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDI 3081
+E + L NDL+GVM LQ +L+ MERDL AI+AKL L KEA+ +E E P +AQAI +
Sbjct: 965 IESTQDLGNDLAGVMALQCKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRL 1024
Query: 3082 KRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEA 3261
I VW+ + ++ EA L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EA
Sbjct: 1025 AEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEA 1084
Query: 3262 EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRM 3441
E+LL QH I+ EID Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL +M
Sbjct: 1085 EKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKM 1144
Query: 3442 WDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITT 3621
W+NRQ+LLSQ Q FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TT
Sbjct: 1145 WENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTT 1204
Query: 3622 MDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSL 3801
MDAN+EKI AV G +L DG+ +D+I +K +ID+R NRE A E+L +LKD L
Sbjct: 1205 MDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDL 1264
Query: 3802 QQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAA 3981
Q+FL DC EL WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA+NKE LD+++
Sbjct: 1265 QKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEG 1324
Query: 3982 INLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWAT 4161
+ L +KPE + ++ L W+ LE TT+ K Q+LFDAN+ +L+ QS AD+ +W
Sbjct: 1325 MQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLH 1384
Query: 4162 QLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENI 4341
LE+++ +D DLT+VN+ ++KQ ++E +M + + I+ + +
Sbjct: 1385 GLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIE-ELQSQAQALSQEGKSTDEV 1443
Query: 4342 KAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGES 4521
+ RL VQ + L PL +R+ L K QF RDV+DE LW+ ER+ LA + + G +
Sbjct: 1444 DSKRLTVQTKFMELLEPLSERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHN 1503
Query: 4522 LPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKKIQELRSAWQE 4698
L L K Q L EI H+P I+ I Q +I D N A +++ +L+ W
Sbjct: 1504 LQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGL 1563
Query: 4699 LKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHER 4878
L E + R L E+ KA Q+ +D EAEAWMSEQELYMM +E+ KDE S + +KKH+
Sbjct: 1564 LIEETEKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQI 1623
Query: 4879 LQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXX 5058
L+ ++ +A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D
Sbjct: 1624 LEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDE 1683
Query: 5059 XXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVA 5238
+ L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARDT NIG ERV
Sbjct: 1684 RHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVD 1743
Query: 5239 NANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
N+ D LI GH+DA TIA WKD LNEAW +LLEL+DTR QIL AS LHKFYHD ++
Sbjct: 1744 TVNNMADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKE 1803
Query: 5419 CLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAG 5598
RI +K +P++LGRD ++V L R H + DI A+G QV Q++ DAA L+ YAG
Sbjct: 1804 IFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAG 1863
Query: 5599 DKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNS 5778
DKA DI RE+EV++AW+ L C+ R RL+DT D F+F +MVRDL+LWM++V R++ +
Sbjct: 1864 DKADDIQKRENEVLEAWKSLLDACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEA 1923
Query: 5779 QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT 5958
QE+P+DVS VELLMNNHQ +KAEIDAR ++F ACI LG+ LL RKHYAS EI++KL++LT
Sbjct: 1924 QEKPRDVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLT 1983
Query: 5959 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
+R EM+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G++++E KLI
Sbjct: 1984 EKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLI 2043
Query: 6139 KKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETS 6318
K+HEAFEKSA +ERF ALE+LTT EL E + ++EE ++R P SP +T +E +
Sbjct: 2044 KRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPP---SPDPNTKVSEEA 2100
Query: 6319 FGAQDDGAKQGEAFEGTL----------IRKHTYESLD-----RKAANRSW 6426
Q D +K + + L R TY++ R A++ SW
Sbjct: 2101 ESQQWDTSKGDQVSQNGLPAEQGSPRVSYRSQTYQNYKNFNSRRTASDHSW 2151
>gi|448251|prf||1916380A beta spectrin (beta fodrin)
Length = 2342
Score = 2145 bits (5558), Expect = 0.0
Identities = 1145/2305 (49%), Positives = 1519/2305 (65%), Gaps = 75/2305 (3%)
Frame = +1
Query: 43 EDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
+D+D +NSSARLFERSRIKALADERE VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTL
Sbjct: 88 LIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDG+A
Sbjct: 148 GLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVVTYYHYF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN
Sbjct: 268 TYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNN 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ EGK
Sbjct: 328 RKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQ------EGK 381
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
LI+DIN+AW+ LEKAEHEREL L+ ELIRQEK +RKA MRETWL+ENQRLVSQ
Sbjct: 382 LISDINKAWERLEKAEHERELALRNELIRQEK--------DRKAAMRETWLSENQRLVSQ 433
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL +VEAATKKHEAIETDI AYEER NYHD +I RK+NV
Sbjct: 434 DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVI 493
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
ARR RLE+++ +QKIF +K LLS+D G HL+ VEDLL
Sbjct: 494 RLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLLLSQDYGKHLLGVEDLL 553
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKHAL+E+DI I ERV A AQ+F DG GYKP I +R ++ Y+EL
Sbjct: 554 QKHALVEADIAIQAERVRGVNASAQKFAT----DGEGYKPC----IRDRVAHMEFCYQEL 605
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
LAAER+ RLE+++RL +F+W++AE E I+E+E++LSS D G+D+ +V LL+KH+
Sbjct: 606 CQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAF 665
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ + + ++ G+++ E GS+ I R+ IR+ L++LSA R +RL
Sbjct: 666 EDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRIKRLEEA 725
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
+QF DADD+D ++ D L+++SS DVG DE + Q L+KKH DV +E+ N+ I L
Sbjct: 726 SLLHQFQADADDIDAWMLDILKIVSSNDVGHDEYSTQSLVKKHKDVAEEITNYRPTIDTL 785
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
H +A +LPQ E PD++ RL ++ E+ L++LRKQ L D L+LYK++S+AD+ E
Sbjct: 786 HEQASALPQAHAESPDVKGRLAGIEERCHEMAELTRLRKQALRDTLALYKMFSEADACEL 845
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
WIDEK + L + +E++E+++HRF++LE +M NQ ++V VN +ARQL++ HP+
Sbjct: 846 WIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHNGHPSE 905
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
+I +Q+KLN RW+Q R++VD+K++ L A ++ + ++C ET +WI +KT+V+E +
Sbjct: 906 KEIRAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQD 965
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L NDL+GVM LQR+L+ MERDL AI+AKL L KEA+ +E E P +AQ + + I V
Sbjct: 966 LGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQILSR-LAEISDV 1024
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W+ + ++ EA L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +L EAE+LL Q
Sbjct: 1025 WEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQ 1084
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
H I+ EID Y EDY+KMR MG+ VTQ QTD QYM LRQRL L GW EL +MW+NRQ+
Sbjct: 1085 HENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYM-LRQRLQALDTGWNELHKMWENRQN 1143
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
LLSQ Q FLRD KQAE L+ QE LA ++P +LE AE +K+ +DF+TTMDAN+E
Sbjct: 1144 LLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEE 1203
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
KI AV G +L DG+ +D+I +K +ID+R NRE A E+L +LKD LQ+FL D
Sbjct: 1204 KINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNREAASELLMRLKDNRDLQKFLQD 1263
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA+NKE LD+++ + L +
Sbjct: 1264 CQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISE 1323
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KPE + ++ L W+ LE TT+ K Q+LFDAN+ +L+ QS AD+ +W LE
Sbjct: 1324 KPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLEKPG 1383
Query: 4180 TREDQPG-DLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ D G DLT + +K + K + + + RL
Sbjct: 1384 FQSDDYGKDLTQSQYSSEKGNRRRRIRWKFGRKRSRNCRPSPGSSRGRAQM--RVDSKRL 1441
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
VQ + L PL +R+ L K QF RDV+DE LW+ ER+ L + + G +L
Sbjct: 1442 TVQTKFMELLEPLSERKHNLLASKEIHQFNRDVEDEILWVGERMPLRTSTDHGHNLQTVQ 1501
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPAFEKKIQELRSAWQELKEAV 4713
L K Q L EI H+P I+ I Q +I D N A +++ +L+ W L E
Sbjct: 1502 LLIKKNQTLQKEIQGHQPRIDDIFERSQNIITDSSSLNAEAIRQRLADLKQLWGLLIEET 1561
Query: 4714 KDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDI 4893
+ R L E+ KA Q+ +D EAEAWMSEQELYMM ++R + + S + +KKH+ L+ +
Sbjct: 1562 EKRHRRLEEAHKAQQYYFDAAEAEAWMSEQELYMMSEKRPRMKQSAVSMLKKHQILEQAV 1621
Query: 4894 DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXY 5073
+ +A+T+ L+ + V + P +E+I +RQ++++KLYAGL+D +
Sbjct: 1622 EDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLF 1681
Query: 5074 ALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDG 5253
L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQERF++FARDT NIG ERV N+
Sbjct: 1682 QLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNNM 1741
Query: 5254 CDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRI 5433
D LI GH+DA IA WKD LNEAW +LLEL+DTR QIL AS LHKFYHD ++ RI
Sbjct: 1742 ADELINSGHSDA-AIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRI 1800
Query: 5434 MEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALD 5613
+K +P++LGRD ++V L R H + DI A+G QV Q++ DAA L+ YAGDKA D
Sbjct: 1801 QDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADD 1860
Query: 5614 IGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPK 5793
I RE+EV++AW+ L G C+ R RL+DT D F+F +MVRDL+LWM++V R++ +QE+P+
Sbjct: 1861 IQKRENEVLEAWKSLLGACEGRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPR 1920
Query: 5794 DVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAE 5973
DVS VELLMNNHQ +KAEIDAR ++F ACI LG+ LL RKHYAS EI++KL++LT +R E
Sbjct: 1921 DVSSVELLMNNHQGIKAEIDARNDSFTACIELGKSLLARKHYASEEIKEKLLQLTEKRKE 1980
Query: 5974 MMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEA 6153
M+ +WEDRWE+L+LILEV+QF+RDA+VAE+WL QEPYL S+E G++++E KLIK+HEA
Sbjct: 1981 MIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEA 2040
Query: 6154 FEKSAFAQEERFLALEKLTTFELKET---QHREE-------------------------- 6246
FEKSA +ERF ALE+LTT EL E Q EE
Sbjct: 2041 FEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPDPNTKVSEEAESQQWDTS 2100
Query: 6247 ---ETAKRRGPAHIGSPSRSTPAAETSF---GAQDDGAKQGEA----------------- 6357
+ ++ PA GSP R ETS GA + E+
Sbjct: 2101 KGDQVSQNGLPAEQGSP-RMAGTMETSEMVNGAAEQRTSSKESSPVPSPTSDRKAKSALP 2159
Query: 6358 ------------------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPK 6483
EG L RKH +E+ ++KA++RSW +Y V+ E+ FYKD K
Sbjct: 2160 AQSAATLPARTLETPAAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAK 2219
Query: 6484 HRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTE 6657
+ H E P++L VA DY+KKK+V LRL G EYLFQ +E+M W+
Sbjct: 2220 SAASGIPYHSEVPVSLKEAICEVALDYKKKKHVFKLRLSDGNEYLFQAKDDEEMNTWIQA 2279
Query: 6658 LQVATGQAQLEEASRSQTLPAEGSA 6732
+ A + + ++ +Q+ PA A
Sbjct: 2280 ISSAISSDKHDTSASTQSTPASSRA 2304
>gi|18859423|ref|NP_571600.1| spectrin, beta, erythrocytic;
beta-spectrin [Danio rerio]
gi|9944861|gb|AAG03012.1| beta-spectrin [Danio rerio]
Length = 2357
Score = 2013 bits (5215), Expect = 0.0
Identities = 1065/2315 (46%), Positives = 1475/2315 (63%), Gaps = 81/2315 (3%)
Frame = +1
Query: 34 TQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDG 213
+ DE +DNSSARLFERSRIKALADERE VQKKTFTKWVNS L RVSC++ DLY+D+RDG
Sbjct: 29 SDDELDNDNSSARLFERSRIKALADEREAVQKKTFTKWVNSILARVSCRISDLYLDLRDG 88
Query: 214 KMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRL 393
+ML++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL
Sbjct: 89 RMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRL 148
Query: 394 TLGLIWTIILRFQIQDITFEDAD-----NHETRSAKEALLLWCQMKTAGYPNVNVKNFST 558
LGLIWTIILRFQIQDI E ETRSAK+ALLLWCQMKTAGYPN+N+ NF+T
Sbjct: 149 ILGLIWTIILRFQIQDIIVETGQADQTGRQETRSAKDALLLWCQMKTAGYPNINITNFTT 208
Query: 559 SWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQ 738
SW+DG+AFNALIHKHRPDLVDY NL++SN +NLQ AF+ AE +LG+ K LD EDV +
Sbjct: 209 SWKDGMAFNALIHKHRPDLVDYGNLKRSNPTHNLQQAFNVAEKKLGVTKLLDPEDVFTEN 268
Query: 739 PDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINA 918
PDEKSIITYVV +YHYF+K+K ++GKRIGKV+++ +E +KMI +YETLSSDLL WI
Sbjct: 269 PDEKSIITYVVAFYHYFSKMKALAVEGKRIGKVLDQAIETEKMIEKYETLSSDLLTWIEQ 328
Query: 919 KIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRP 1098
I +LN R N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+
Sbjct: 329 TIVVLNNRKLANSLTGVQQQLQAFNSYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKV 388
Query: 1099 FVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTE 1278
+ P+EG L++DIN+AW+ LEKAE++RE VL++ELIRQEKLEQ+A RF+RKA MRETWL E
Sbjct: 389 YTPKEGALVSDINKAWERLEKAEYDRERVLRDELIRQEKLEQMARRFDRKAAMRETWLME 448
Query: 1279 NQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKIN 1458
NQRLVSQDNFG DL +VEAA KKH+AIETDI AYEER YHD +I+
Sbjct: 449 NQRLVSQDNFGYDLPAVEAAKKKHDAIETDIAAYEERVQALVALSKELESERYHDAKRID 508
Query: 1459 ERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHL 1638
RK+N+ ARR RL+ ++ +Q+IF +K RLLS D G HL
Sbjct: 509 ARKDNILRLWDYLQELLKARRGRLDKNLTLQRIFQEMLHIISWMDEMKGRLLSPDFGKHL 568
Query: 1639 MDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVL 1818
++VEDLLQKH+L+E+DI + ERV ++ A A +F N G YKP +P I +R L
Sbjct: 569 LEVEDLLQKHSLVEADIAVQAERVKSANAAALKFAN-----GDSYKPCDPQVIRDRVQHL 623
Query: 1819 QKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHL 1998
Y++L LAA+RK RLE ++RL F W++AELE I+E+EQ+ SS D G+D+ +V L
Sbjct: 624 DLCYQQLCALAAQRKARLEQSRRLWNFLWEIAELESWIREREQIFSSLDYGKDLTSVLIL 683
Query: 1999 LAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASR 2178
+KH E+ L L ++ G+ + GS + R+ +++ +L+EL+A R
Sbjct: 684 QSKHSVFEDELAASRDNLKQVMDEGESMIQIKHLGSPKVQQRMNDVQRQWQQLEELAAFR 743
Query: 2179 KERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNF 2358
K+ L ++QF DADD+ +L D +R MSS+DVG DE T Q LLKKH D+ DE
Sbjct: 744 KQNLQDTQRFFQFQGDADDLKAWLVDAMRQMSSDDVGHDEYTTQRLLKKHRDLRDEAAKN 803
Query: 2359 DQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYS 2538
I L +A +LP+E R PDI+ RL+ EL LS LR+++L D ++LY ++S
Sbjct: 804 GATIDALSKQANALPEELRNTPDIQGRLNDIRDMYIELLTLSDLRQKKLDDTMALYTIFS 863
Query: 2539 DADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLL 2718
+ D+ E W+ +K L L ++E++EI+++R L Q+M N + +V NVN A+QL
Sbjct: 864 ETDACELWMGQKETWLVGLETPENLEDLEIVQNRLSILAQEMGNMQTRVDNVNKAAKQLE 923
Query: 2719 NVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTR 2898
+ HP + + Q +LN RW + MV+ K++ ++ A L + +DC ET +WI++KTR
Sbjct: 924 DSRHPQTKQVKDCQIRLNKRWEAFKAMVEDKKHRVDSALSLHNYDLDCDETESWIKEKTR 983
Query: 2899 VLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIRED 3078
V+E + L NDL+ V+ +QR+L MERDL AIQ KL+ L EA + +E P+ A I
Sbjct: 984 VIESTQDLGNDLAAVITIQRKLFGMERDLAAIQDKLNFLRDEAQKLVKEHPENASDILAR 1043
Query: 3079 IKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAE 3258
+ + WD L + +++ E L E LQ FL+D+D FQAWL +Q+ VASE+ P L E
Sbjct: 1044 QEELDAAWDTLKRTLKDREDSLGEVSKLQTFLQDMDDFQAWLFKSQKAVASEDMPDGLPE 1103
Query: 3259 AEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTD-PQYMFLRQRLAGLQEGWEELQ 3435
AEQLLN H A+R ++DG+ EDY +++ G V Q Q D PQY L QRL GL +GW EL
Sbjct: 1104 AEQLLNLHDALRHDMDGHEEDYHRVKDTGAAVIQGQEDDPQYQQLEQRLEGLDKGWGELH 1163
Query: 3436 RMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFI 3615
+MWD+R++ L QGL Q F+RDAKQA+ +L+ QE LA D P +L+ AE LK+H+DF+
Sbjct: 1164 KMWDSRKNFLDQGLGFQQFMRDAKQADAILNNQEYTLAHVDKPDTLDGAEKALKKHEDFV 1223
Query: 3616 TTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDAL 3795
TTMDAN EKI + G +L + + K+ K +I+ER N++KA+EV KLKD
Sbjct: 1224 TTMDANKEKILSTLETGQRLVDSENLYSGKVKDKMSSIEERNKKNQDKAKEVSGKLKDNR 1283
Query: 3796 SLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKH 3975
LQ FL + +L WI EKM+ AQD +Y +A+ + SK+ +HQAF +ELA+NK+ L +
Sbjct: 1284 ELQHFLQNTQDLTLWINEKMLTAQDTSYDEARNLHSKWQKHQAFMAELASNKDWLHNIDK 1343
Query: 3976 AAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEW 4155
L + KPE+ + ++ +L WD+LE TT+EK + LFDANR +L+ QS+AD+K+W
Sbjct: 1344 EGQELMESKPEFEPIVKDRLAKLHELWDKLESTTQEKARLLFDANRSELFDQSLADLKKW 1403
Query: 4156 ATQLENEMTR--EDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDE 4329
+L+ ++ E++ DLT+ N+ ++K + E ++ +A+ ++ D+
Sbjct: 1404 LAELQQQLQGDVEEEVKDLTSANILLKKHQITENQVRDRARELEELQEAVQQHGSLREDQ 1463
Query: 4330 LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQN 4509
E ++ + +Q Q+L PL R+ LE KA QF RD+ DE LW++ERL +A + +
Sbjct: 1464 PE-LEIEQQNLQRDFQKLLTPLSQRKGKLEAAKAVHQFFRDLADEILWVNERLPMAMSDD 1522
Query: 4510 LGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELID--EGHANGPAFEKKIQELR 4683
G +L L K Q L EID H+P I+++ G+ + EG +++++L+
Sbjct: 1523 HGNNLQTVQLLLKKNQSLQKEIDGHQPRIDEVLERGRRMAAAAEGSPEEERMSEEMKKLQ 1582
Query: 4684 SAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQI 4863
W +L+E + R+ L S +A Q+ D ++EAW+ EQELYM+ DE KDE S +
Sbjct: 1583 EVWAQLQEEMAKRRERLYGSNEAQQYYNDADDSEAWIGEQELYMIADEMAKDEQSAMIML 1642
Query: 4864 KKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXX 5043
K+H L+ +D +A +I+ LA +A K + E+ P E I RQ Q++K YAGL++
Sbjct: 1643 KRHLVLKQTVDDYAYSIQQLADRAQKMLAEEHPDGEAIIRRQGQVDKQYAGLKELAEDRK 1702
Query: 5044 XXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIG 5223
+ L RE++DL QWIA+++VVA SQE GQD +HV +L+++F++FAR+T +G
Sbjct: 1703 KKLDHTYHHFLLSREVEDLEQWIAERDVVASSQEMGQDLDHVTILRDKFREFARETGTVG 1762
Query: 5224 SERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFY 5403
ERV N D LI GH+++ T+A WKD +NE+W +LLEL+DTRAQ+L +S L K++
Sbjct: 1763 QERVDTVNRIIDELIEGGHSESATLAEWKDGVNESWADLLELIDTRAQLLTSSYDLLKYF 1822
Query: 5404 HDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELR 5583
+D ++ + I EK + +P+DLG D S + R H + +DI+++G+QV Q + AA L
Sbjct: 1823 YDGKELVGHIEEKKNELPEDLGEDFSKAESFHRMHAAFERDISSLGKQVKQFQETAARLH 1882
Query: 5584 DGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVK 5763
YAGD+A I + E EVV+AW+ L C R +L +T+D F+F MVRDL+ WM+ +
Sbjct: 1883 AQYAGDQATAIQATEKEVVEAWKGLLDACAGRRKQLEETADKFRFFTMVRDLMAWMESIL 1942
Query: 5764 REMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKK 5943
+++ +QE+P+DVS VELLM HQ ++AEI+ R FN C+ LG+ LL RKH S+EI++K
Sbjct: 1943 QQIETQEKPRDVSSVELLMKYHQGIRAEIETRGPKFNQCVQLGQALLERKHKDSAEIKEK 2002
Query: 5944 LIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEE 6123
L++L +R EMM +W+DRW++L+L+LEV QFARDA+VAE+WL AQEPY+ SK+ G+ ++E
Sbjct: 2003 LMQLVEKRKEMMLKWDDRWDWLRLLLEVCQFARDASVAEAWLIAQEPYVASKDVGQTVDE 2062
Query: 6124 TIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHRE----------EETAKRRGPA 6273
KL+K+HEAFEKS EERF ALE+LTT EL E + ++ E+ ++R
Sbjct: 2063 VEKLLKRHEAFEKSTATWEERFSALERLTTLELLEIRKQQQEIQQYRQEAEKESRREDTG 2122
Query: 6274 HIGSPSRSTPAAETSFGA-----QDDGAKQGEA--------------------------- 6357
S+ P E S G G A
Sbjct: 2123 FAEESSQLYPTEEQSLSGLGVIEPSSGGVDGTAGESTVPLISEMQESVSLELDPSTSIQV 2182
Query: 6358 ---------------------FEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYK 6474
EGTL RKH E ++KA NRSW LY VL+ LS YK
Sbjct: 2183 TKETEKAASLPTESTQVQPVLMEGTLARKHELEGPNKKAPNRSWNNLYCVLKPGHLSIYK 2242
Query: 6475 DPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRW 6648
D K SV HGE P+ L S + ++Y+KKK V LRL G+EYLFQC EE++Q W
Sbjct: 2243 DAKSFSHSVTFHGEEPLTLTNSSCEILTNYKKKKQVFKLRLGDGSEYLFQCKDEEELQNW 2302
Query: 6649 LTELQVATGQAQLEE------ASRSQTLPAEGSAT 6735
++ A Q Q+EE ++ +LP S T
Sbjct: 2303 TQAIEQA-AQVQIEEPVAGPSGVKALSLPPPSSTT 2336
>gi|47209542|emb|CAF96656.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2275
Score = 1970 bits (5103), Expect = 0.0
Identities = 1038/2139 (48%), Positives = 1400/2139 (64%), Gaps = 94/2139 (4%)
Frame = +1
Query: 79 ERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERL 258
+ R ++ DERE VQKKTFTKWVNSHL RVSC++ DLYMD+RDG+ML++LL VLSGE+L
Sbjct: 155 QSQRSFSVGDEREAVQKKTFTKWVNSHLSRVSCRITDLYMDLRDGRMLIKLLEVLSGEKL 214
Query: 259 -----PKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIIL 423
PKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGLIWTIIL
Sbjct: 215 VGPKLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIIL 274
Query: 424 RFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKH 603
RFQ + MKTAGY NVN+ NF+TSWRDG+AFNA+IHKH
Sbjct: 275 RFQGR-----------------------LMKTAGYSNVNIHNFTTSWRDGMAFNAIIHKH 311
Query: 604 RPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYH 783
RPDL+D+D L+KSNA YNLQ+AF+ AE LGL K LD ED++VD PDEKSIITYVVTYYH
Sbjct: 312 RPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYH 371
Query: 784 YFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLE 963
YF+K+K ++GKRIGKV++ +E +KMI +YE+L+SDLLEWI I +LN R F N+L
Sbjct: 372 YFSKMKALKVEGKRIGKVLDHAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLV 431
Query: 964 GVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRA 1143
GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ F PREGKLI+DIN+A
Sbjct: 432 GVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVFTPREGKLISDINKA 491
Query: 1144 WQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLS 1323
W+ LE+AEHEREL L+ ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQDNFG DL
Sbjct: 492 WERLERAEHERELALRTELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGCDLQ 551
Query: 1324 SVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXX 1503
+VEAATKKHEAIETDI AYEER +YHD ++ RK+NV
Sbjct: 552 AVEAATKKHEAIETDIAAYEERVQAVVAVAKELEAESYHDIKRVTARKDNVTRLWEYLLE 611
Query: 1504 XXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLES 1683
ARR RLE+++ +Q++F +K LLS+D G HL+ VEDLLQKHAL+E+
Sbjct: 612 LLKARRQRLEMNLGLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGVEDLLQKHALVEA 671
Query: 1684 DINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERK 1863
DI I +RV N + AQ+F D GY+P +P I +R + Y+EL LAAER+
Sbjct: 672 DIGIQADRVRNVNSNAQKF----AMDVEGYRPCDPQVIQDRVTHMDFCYQELSQLAAERR 727
Query: 1864 RRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLE 2043
RLE+++RL +F+W++AE E I+E+EQ+LSS D G+D+ LL++HK E+ +
Sbjct: 728 ARLEESRRLWKFFWEMAEEEGWIREKEQILSSEDHGKDLTGALRLLSQHKALEDEMSGRA 787
Query: 2044 KYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFT 2223
+L + G+EL G+D I R+ +I+ +L+ LSA RK RL +QF
Sbjct: 788 GHLQQTIRQGEELVANHHFGADKIKERIQDIQAQWAELERLSAVRKSRLQEACNKHQFQA 847
Query: 2224 DADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLP 2403
DADD+D ++ D LR++SS DVG DE + Q L+KKH DV +E+ ++ I LH ++ +LP
Sbjct: 848 DADDIDTWMLDILRIVSSVDVGHDEFSTQALVKKHKDVAEEMGSYRPVIDALHEQSRALP 907
Query: 2404 QEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKL 2583
+ + +++ RL ++ E+ L++LRKQ L DAL+LYK++S+A++ E+WIDEK +
Sbjct: 908 VDGADSEEVQNRLAGIEERYKEVVELTRLRKQALQDALTLYKMFSEANACEAWIDEKEQW 967
Query: 2584 LATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQN 2763
L ++ +E++E+++HRF++LE +M NQ ++V VN +ARQL++ HP+ +I +Q+
Sbjct: 968 LNSMDIPEKLEDLEVVQHRFESLEPEMNNQASRVAVVNQVARQLIHSGHPSEKEIKSQQD 1027
Query: 2764 KLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGV 2943
KLN RW+Q RD+ DQK++ L A ++ + ++C ET +WI++KT+V+E + L NDL+GV
Sbjct: 1028 KLNTRWSQFRDLADQKKDALNSALGVQNYHLECNETKSWIKEKTKVIESTQELGNDLAGV 1087
Query: 2944 MKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKV 3123
M LQR+L+ MERDL AI+ KL L KEA+ + E P ++Q I+ + I VW + +
Sbjct: 1088 MALQRKLTGMERDLVAIEDKLGDLGKEAERLASEHPDQSQTIKGRLAEITHVWGEMKDTM 1147
Query: 3124 REHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEI 3303
+ E L EA LQ+FLRDLD FQ+WL+ TQ +ASE+ P +LAEAE+LL QH I+ EI
Sbjct: 1148 KNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAEKLLAQHEGIKNEI 1207
Query: 3304 DGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNL 3483
Y EDY+KMR MG+ VTQ QTD QYMFLRQRL L GW EL RMW+NRQ+LLSQ +
Sbjct: 1208 RNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHRMWENRQNLLSQSHSY 1267
Query: 3484 QMFLRDAKQAEVMLSQ------------------------------------QENYLAKD 3555
Q+FLRD KQAE L+ QE LA
Sbjct: 1268 QLFLRDTKQAEAFLNNQVSAANQTVLLSSQTGNGFGQVNPAAESHTAASPVFQEYVLAHT 1327
Query: 3556 DIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDE 3735
++P +LE AE +K+ +DF+TTMDAN+EKI V G +L DG+ +++I +K +ID+
Sbjct: 1328 EMPTTLEAAEASIKKQEDFMTTMDANEEKIIGVVDAGRRLVADGNINSERIQEKVDSIDQ 1387
Query: 3736 RRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVR 3915
R R A E+L +LKD LQ+FL DC EL WI EKM+ AQD TY +A+ + SK+++
Sbjct: 1388 RHKKTRAAAVELLDRLKDNRDLQKFLQDCQELSLWIGEKMLTAQDMTYDEARNLHSKWLK 1447
Query: 3916 HQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQK 4095
HQAF +EL +NKE LD++ L +KP+ + ++ L + W ELE TT+ K +
Sbjct: 1448 HQAFMAELQSNKEWLDKIDKDGQTLMLEKPDTEAMVQEKLAWLKSTWAELESTTQTKAKC 1507
Query: 4096 LFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQH 4275
LFDAN+ +L+ QS AD+ +W LE ++ ++ DLT+VN+ ++KQ ++E+++ + +
Sbjct: 1508 LFDANKAELFTQSCADLDKWLGSLEAQLQSDEYGKDLTSVNILLKKQQILESQVEVRQKE 1567
Query: 4276 IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDV 4455
++ E + R++V+ + L PL RR L + QF RDV
Sbjct: 1568 VEELQNQSQVLSQEGKGS-EEVDGQRVSVERKFHLLLEPLKKRRDNLMVSREIHQFNRDV 1626
Query: 4456 DDE---KLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQEL 4626
+DE LW+ ERL +A + + G +L L K Q L EI H+P + I Q +
Sbjct: 1627 EDEIVSLLWVEERLPVAMSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRYDDIFERSQHV 1686
Query: 4627 IDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQE 4806
+ E +++ EL S WQ + E + R L E+ +A Q+ +D EAEAWMSEQE
Sbjct: 1687 LREDGPTAQLIGQRLAELTSLWQRIGEEAEKRHERLSEAHRAQQYYFDAAEAEAWMSEQE 1746
Query: 4807 LYMMQDERGK----------------------DEFSTKNQIKKHERLQSDIDKFADTIRA 4920
LYMM +E+ K DE S+ +KKH+ L+ ++ +ADT+
Sbjct: 1747 LYMMSEEKAKVRWDAAAAVGLLDRAYRFVSLQDEQSSVFMLKKHQILEQAVEDYADTVHQ 1806
Query: 4921 LATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDL 5100
L+ + V P +E+I +RQ+Q++KLYAGL+D + L+RE+DDL
Sbjct: 1807 LSATSRGLVAAGHPESERIGMRQSQVDKLYAGLKDLSEERRGKLDERFRLFQLNREVDDL 1866
Query: 5101 LQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGH 5280
QWIA++EVVAGS E GQDYEHV MLQERF++FARDT IG ERV N D LI GH
Sbjct: 1867 EQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGTIGQERVDAVNRQADELINAGH 1926
Query: 5281 TDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD 5460
+DA TIA WKD LNEAW +LLEL+DTR QIL AS LH+FYHD ++ LSRI++K +P+
Sbjct: 1927 SDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHQFYHDAKEILSRILDKHKKLPE 1986
Query: 5461 DLGRDSSSVGALSRKHQNYLKDIAAIGEQVA----------------------------Q 5556
+LGRD ++V L R H + DI A+G QVA Q
Sbjct: 1987 ELGRDQNTVETLQRMHTAFEHDIQALGTQVATLARLERLLRALPGTAGLRSDSSLFQVRQ 2046
Query: 5557 IERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRD 5736
++ DA L+ YAGDKA DI RE+EV++AW++L + R +L+DT D F+F +MVRD
Sbjct: 2047 LQEDATRLQAAYAGDKADDIQKREAEVLEAWKNLLEAVEGRRLKLVDTGDKFRFFSMVRD 2106
Query: 5737 LLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKH 5916
L+LWM++V R + +QE P+DVS VELLMNNHQ +KAEIDAR ++F CI LG+ LL RKH
Sbjct: 2107 LMLWMEDVIRLIEAQENPRDVSSVELLMNNHQGIKAEIDARNDSFTCCIELGKTLLARKH 2166
Query: 5917 YASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLIS 6096
YAS EI++KL++LT +R EM+ +WEDRWE+L+L+LEV+QF+RDA+VAESWL QEPYL S
Sbjct: 2167 YASEEIKEKLLQLTDKRKEMIDKWEDRWEWLRLVLEVHQFSRDASVAESWLLGQEPYLSS 2226
Query: 6097 KEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
+E G+N +E KLIK+HEAFEKSA EERF ALE+LTT
Sbjct: 2227 REVGQNADEVEKLIKRHEAFEKSAATWEERFSALERLTT 2265
Score = 197 bits (500), Expect = 4e-48
Identities = 246/1302 (18%), Positives = 505/1302 (37%), Gaps = 90/1302 (6%)
Frame = +1
Query: 2626 IMKHRFDTLEQDM---KNQEAKVTNVNDLARQLL-----------NVEHPNSDDIL---- 2751
I KHR D ++ D N + N +LA Q L +V+HP+ I+
Sbjct: 308 IHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVV 367
Query: 2752 ---HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDAL 2922
H +K+ A + + + + +E +E + + + WIE +T ++ ++
Sbjct: 368 TYYHYFSKMKALKVEGKRIGKVLDHAIETEKMIEKYESLASDLLEWIE-QTIIILNNRKF 426
Query: 2923 TNDLSGVMKLQRRLSMMER--------DLGAIQAKLDSLHKE--ADDIERERPQEAQAIR 3072
N L GV + + + + G ++ L ++ + A++ + P+E + I
Sbjct: 427 ANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVFTPREGKLIS 486
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDL----------QRFLRDLDHFQAWLTATQRQ 3222
+ I++ W+ L + EHE +L +L +RF R + WL+ QR
Sbjct: 487 D----INKAWERLERA--EHERELALRTELIRQEKLEQLARRFDRKAAMRETWLSENQRL 540
Query: 3223 VASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRL 3402
V+ + L E +H AI +I Y E + + A+ + + ++ + R
Sbjct: 541 VSQDNFGCDLQAVEAATKKHEAIETDIAAYEERVQAVVAVAKEL-EAESYHDIKRVTARK 599
Query: 3403 AGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQA 3582
+ WE L + R+ L L LQ ++ + + + L D + L
Sbjct: 600 DNVTRLWEYLLELLKARRQRLEMNLGLQRVFQEMLYIMDWMDEMKMLLLSQDYGKHLLGV 659
Query: 3583 ENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQD--GHYAADK--IHKKARNIDERRGAN 3750
E+ L++H + +++R V + D G+ D I + ++D
Sbjct: 660 EDLLQKHALVEADIGIQADRVRNVNSNAQKFAMDVEGYRPCDPQVIQDRVTHMDFCYQEL 719
Query: 3751 REKAQEVLKKLKDALSLQQFLSDCDELREWIEEK-MIRAQDETYRDAKTITSKFVRHQAF 3927
+ A E +L+++ L +F + E WI EK I + ++ +D +H+A
Sbjct: 720 SQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEQILSSEDHGKDLTGALRLLSQHKAL 779
Query: 3928 QSELAANKERLDQLKHAAINLGDDKPEYH----GTIDPQIEELATQWDELEKTTEEKGQK 4095
+ E++ L Q I G++ H I +I+++ QW ELE+ + + +
Sbjct: 780 EDEMSGRAGHLQQ----TIRQGEELVANHHFGADKIKERIQDIQAQWAELERLSAVRKSR 835
Query: 4096 LFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQH 4275
L +A + + D+ W + ++ D D + ++K + EM
Sbjct: 836 LQEACNKHQFQADADDIDTWMLDILRIVSSVDVGHDEFSTQALVKKHKDVAEEMGSYRPV 895
Query: 4276 IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDV 4455
ID D E ++ ++E+ + + R++AL+ ++ +
Sbjct: 896 IDALHEQSRALPVDGADS-EEVQNRLAGIEERYKEVVELTRLRKQALQDALTLYKMFSEA 954
Query: 4456 DDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDE 4635
+ + WI E+ + ++ E L D +Q + L E++N + + ++LI
Sbjct: 955 NACEAWIDEKEQWLNSMDIPEKLEDLEVVQHRFESLEPEMNNQASRVAVVNQVARQLIHS 1014
Query: 4636 GHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQ-ELY 4812
GH + + + +L + W + ++ +K L + + +C E ++W+ E+ ++
Sbjct: 1015 GHPSEKEIKSQQDKLNTRWSQFRDLADQKKDALNSALGVQNYHLECNETKSWIKEKTKVI 1074
Query: 4813 MMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQA 4992
E G D +K ++ D+ D + L +A + E ++ I+ R A
Sbjct: 1075 ESTQELGNDLAGVMALQRKLTGMERDLVAIEDKLGDLGKEAERLASEHPDQSQTIKGRLA 1134
Query: 4993 QIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQ 5172
+I ++ ++D R++DD W++ + S++ +
Sbjct: 1135 EITHVWGEMKDTMKNREESLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLAEAE 1194
Query: 5173 MLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWK--DSLNEAWENLLE 5346
L + + + N + + G ++ G TDA + L + +L+ W L
Sbjct: 1195 KLLAQHEGIKNEIRNYEEDYQKMRDMG--EMVTQGQTDAQYMFLRQRLQALDTGWNELHR 1252
Query: 5347 LMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHA------MPDDLGRDSSSVGALSRKH 5508
+ + R +L S F D + + + + A + G V + H
Sbjct: 1253 MWENRQNLLSQSHSYQLFLRDTKQAEAFLNNQVSAANQTVLLSSQTGNGFGQVNPAAESH 1312
Query: 5509 QN----YLKDIAAIGEQVAQIERDAAELRDGY------------------AGDKALDIGS 5622
+ + + A E +E A ++ AG + + G+
Sbjct: 1313 TAASPVFQEYVLAHTEMPTTLEAAEASIKKQEDFMTTMDANEEKIIGVVDAGRRLVADGN 1372
Query: 5623 RESEVVKA------WRH--LRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNS 5778
SE ++ RH R RL D DL KF+ ++L LW+ E + + +
Sbjct: 1373 INSERIQEKVDSIDQRHKKTRAAAVELLDRLKDNRDLQKFLQDCQELSLWIGE--KMLTA 1430
Query: 5779 QERPKDVS-GVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKL 5955
Q+ D + + HQ+ AE+ + +E + G+ L+ K + +++KL L
Sbjct: 1431 QDMTYDEARNLHSKWLKHQAFMAELQSNKEWLDKIDKDGQTLMLEKPDTEAMVQEKLAWL 1490
Query: 5956 TTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKL 6135
+ AE+ + + + L + F + A + WL + E L S EYG++L L
Sbjct: 1491 KSTWAELESTTQTKAKCLFDANKAELFTQSCADLDKWLGSLEAQLQSDEYGKDLTSVNIL 1550
Query: 6136 IKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
+KK + E +++ L+ + +E + EE +R
Sbjct: 1551 LKKQQILESQVEVRQKEVEELQNQSQVLSQEGKGSEEVDGQR 1592
Score = 81.6 bits (200), Expect = 2e-13
Identities = 91/459 (19%), Positives = 171/459 (36%), Gaps = 22/459 (4%)
Frame = +1
Query: 1096 PFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLT 1275
P R G + +++ + L+ ER L E +L QL NR+ + E W+
Sbjct: 1820 PESERIGMRQSQVDKLYAGLKDLSEERRGKLDERF----RLFQL----NREVDDLEQWIA 1871
Query: 1276 ENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAY-EERXXXXXXXXXXXXXXNYHDQAK 1452
E + + G D V ++ D +ER + D A
Sbjct: 1872 EREVVAGSHELGQDYEHVTMLQERFREFARDTGTIGQERVDAVNRQADELINAGHSDAAT 1931
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I E K+ + R L S + + +H K + L E+LG
Sbjct: 1932 IAEWKDGLNEAWADLLELIDTRTQILAASYELHQFYHDAKEILSRILD-KHKKLPEELGR 1990
Query: 1633 HLMDVEDLLQKHALLESDINIIGERV---------------------NNSIAQAQRFRNP 1749
VE L + H E DI +G +V ++S+ Q ++ +
Sbjct: 1991 DQNTVETLQRMHTAFEHDIQALGTQVATLARLERLLRALPGTAGLRSDSSLFQVRQLQED 2050
Query: 1750 DGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHG 1929
+ Y + I +R + + +K LL+ R+ +L D +F+ V +L
Sbjct: 2051 ATRLQAAYAGDKADDIQKREAEVLEAWKNLLEAVEGRRLKLVDTGDKFRFFSMVRDLMLW 2110
Query: 1930 IKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSD 2109
+++ +++ + + RD+ +V L+ H+ + + GK L S+
Sbjct: 2111 MEDVIRLIEAQENPRDVSSVELLMNNHQGIKAEIDARNDSFTCCIELGKTLLARKHYASE 2170
Query: 2110 NIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVG 2289
I +L ++ D ++ + R E L +E +QF DA + +L +SS +VG
Sbjct: 2171 EIKEKLLQLTDKRKEMIDKWEDRWEWLRLVLEVHQFSRDASVAESWLLGQEPYLSSREVG 2230
Query: 2290 KDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQ 2406
++ V+ L+K+H+ +++ L PQ
Sbjct: 2231 QNADEVEKLIKRHEAFEKSAATWEERFSALERLTTVRPQ 2269
Score = 42.7 bits (99), Expect = 0.12
Identities = 48/200 (24%), Positives = 89/200 (44%), Gaps = 16/200 (8%)
Frame = +1
Query: 5713 KFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLM---NNHQSLKAEIDAREE-NFNAC 5880
K+ ++ DLL W+++ +N+++ + GV+ + N +++++ E+ N
Sbjct: 402 KYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVL 461
Query: 5881 ISLGRDLL---NRKHYAS------SEIEKKLIKLTTERAEMMRRWEDRWEYLQ---LILE 6024
+ + + N+K + S+I K +L ERAE R R E ++ L
Sbjct: 462 LFTIQSKMRANNQKVFTPREGKLISDINKAWERL--ERAEHERELALRTELIRQEKLEQL 519
Query: 6025 VYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
+F R AA+ E+WL + + +G +L+ KKHEA E A EER A+
Sbjct: 520 ARRFDRKAAMRETWLSENQRLVSQDNFGCDLQAVEAATKKHEAIETDIAAYEERVQAVVA 579
Query: 6205 LTTFELKETQHREEETAKRR 6264
+ E+ H + R+
Sbjct: 580 VAKELEAESYHDIKRVTARK 599
Score = 37.7 bits (86), Expect = 3.9
Identities = 19/31 (61%), Positives = 24/31 (77%)
Frame = +1
Query: 13 DGNSGAYTQDEDYDDNSSARLFERSRIKALA 105
DG + + D+ ++NSSARLFERSRIKALA
Sbjct: 18 DGVNNRWDADDWDNENSSARLFERSRIKALA 48
>gi|47227240|emb|CAG00602.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2413
Score = 1949 bits (5050), Expect = 0.0
Identities = 1021/2114 (48%), Positives = 1376/2114 (64%), Gaps = 37/2114 (1%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALA------------------------------------D 108
+ D+D +NSSARLFERSRIKALA D
Sbjct: 29 ETDWDNENSSARLFERSRIKALAAMDWDHRNREPSLSPAAFVNQVQYANILEGRFKQLQD 88
Query: 109 ERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRI 288
ERE VQKKTFTKWVNSHL RV+C++ DLY D+RDG+ML+RLL VLSGE+LP+PT G+MRI
Sbjct: 89 EREAVQKKTFTKWVNSHLGRVTCRIGDLYTDLRDGRMLIRLLEVLSGEQLPRPTKGRMRI 148
Query: 289 HCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNH 468
HCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGLIWTIILRFQIQDI+ E DN
Sbjct: 149 HCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNK 208
Query: 469 ETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNA 648
E +SAK+ALLLWCQMKTAGYPNVN+ NF+TSWRDGLAFNA++HKHRPDL+D++NL++SNA
Sbjct: 209 EKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGLAFNAIVHKHRPDLIDFENLKRSNA 268
Query: 649 LYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRI 828
YNLQ+AF+ AE +LGL K LD EDVNVDQPDEKSIITYV YYHYF+K+K ++GKRI
Sbjct: 269 HYNLQNAFNVAEKELGLTKLLDPEDVNVDQPDEKSIITYVAPYYHYFSKMKALAVEGKRI 328
Query: 829 GKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQ 1008
GKV++ +E D++I +YETL+S+LL+WI I LN+R N+L VQ QL FN YRT
Sbjct: 329 GKVLDYAIEADQLIEKYETLASELLQWIEQTIVTLNDRQLANSLSAVQNQLQAFNSYRTV 388
Query: 1009 EKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVL 1188
EKPPKF EKG LEVLLFT+QS MRANNQ+ ++P+EGKLI+DIN+AW+ LEKAEHEREL L
Sbjct: 389 EKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPKEGKLISDINKAWERLEKAEHERELAL 448
Query: 1189 KEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETD 1368
+ ELIRQEKLE LAARF+RKA MRETWL+ENQRLVSQDNFG +L +VEAAT+KHEAIETD
Sbjct: 449 RNELIRQEKLEMLAARFDRKAAMRETWLSENQRLVSQDNFGTNLGAVEAATRKHEAIETD 508
Query: 1369 IFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAI 1548
I AY ER YHD +I R++NV ARR RL +
Sbjct: 509 IGAYWERVAAVQAVARELEAEGYHDVRRILARRDNVLRLWEYLKELLAARRERLNAHRDL 568
Query: 1549 QKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQ 1728
Q++F +K RL S D G HL DV DLLQKH L+E+D + ER+
Sbjct: 569 QRLFQEMRYIMDWMGDMKGRLQSPDSGKHLHDVLDLLQKHTLVEADSSAQAERIKAVQGA 628
Query: 1729 AQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWD 1908
AQRF + + YKP EPG + E+ D+L + Y+EL LA +R+ +LED++RL QF WD
Sbjct: 629 AQRFTSYE----QAYKPCEPGLVSEKVDLLGQAYEELGQLAVKRREQLEDSRRLWQFLWD 684
Query: 1909 VAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQD 2088
V E I+EQEQ+L+S D GRD+ + HLL+KH+ + + L G+ L
Sbjct: 685 VGEEAAWIREQEQILASGDCGRDLTSALHLLSKHEAFRDEMAARYGPLSNSIAVGEALIK 744
Query: 2089 ESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRV 2268
E G+ + R+ +IR + L+E S R++ L V +QF TDA+D++ ++ +T R
Sbjct: 745 EGHFGAPEVRERIEDIRGQWSHLEETSQLREQSLKESVALHQFQTDANDMEAWIMETFRQ 804
Query: 2269 MSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDT 2448
+SS++VG DE + Q L +K ++ +E+++ I LH +A++LPQ P++ RL
Sbjct: 805 VSSQEVGHDEFSTQTLARKQREIEEEIKSHRPLIDSLHEQAQALPQAYVNFPEVDGRLPA 864
Query: 2449 TLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEI 2628
++ ELE+LS R+Q L AL+LY+++S+A + W++EK + L + +E++E+
Sbjct: 865 IEQRYEELESLSVARRQALEGALALYRMFSEAGACLVWVEEKEQRLHGMEIPTKLEDLEV 924
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
++ RF+TLE +M N A+VT VN A QLL+ + N D I +++LN RW + + Q
Sbjct: 925 VQQRFETLEPEMNNLGARVTYVNQKAEQLLSSDSCNKDQIHQTRDQLNDRWKEFEQLAGQ 984
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
K+ +LE A ++ + ++C E TW+++KT+V+E + L NDL+GVM LQR+L+ MERDL
Sbjct: 985 KKQDLESALNIQNYHLECNEIQTWMKEKTKVIESTQGLGNDLAGVMALQRKLTGMERDLE 1044
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
AIQ KLD L EA+ + RE P +A I+ + I +VW+ LN ++ E L EA LQ
Sbjct: 1045 AIQGKLDDLRNEAEKLAREHPDQAGEIQGRLTEIQEVWEDLNDTMKRREESLGEASKLQG 1104
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
FLRDLD FQ WL+ TQ VASE+ P SL EAE LL QH +I+ E+D Y EDY+KMRA+G+
Sbjct: 1105 FLRDLDDFQTWLSRTQTAVASEDIPTSLPEAESLLAQHESIKNEVDNYKEDYEKMRAVGE 1164
Query: 3349 RVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLS 3528
VTQ QTD Q+MFL QRL L GW EL+RMW+NR LL+Q + Q FLRDAKQAE L+
Sbjct: 1165 EVTQGQTDAQHMFLAQRLQALDTGWHELRRMWENRHSLLAQAFDFQTFLRDAKQAETFLN 1224
Query: 3529 QQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKI 3708
QE L+ ++P SL+ AE +K+H+DF+TT +A++EKI +V G +L D + +DKI
Sbjct: 1225 SQEYVLSHTEMPTSLQGAEEAIKKHEDFLTTTEASEEKINSVVESGRRLINDCNANSDKI 1284
Query: 3709 HKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDA 3888
+K +I ER N+E A E+L KLKD LQ FL D EL WI EKM+ AQD +Y +A
Sbjct: 1285 QEKVDSILERHRKNKEAANELLAKLKDNRELQHFLQDGQELTLWINEKMLTAQDMSYDEA 1344
Query: 3889 KTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELE 4068
+ + SK+ +HQAF +ELA+NK+ LD++ L +KPE ++ +++L QW+ELE
Sbjct: 1345 RNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVAEKPELKPVVEQTLQDLQRQWEELE 1404
Query: 4069 KTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIE 4248
TT+ K Q LFDANR +L+ QS + + W LE ++ +D DLT+VN+ ++K ++E
Sbjct: 1405 GTTQTKAQCLFDANRAELFTQSCSALDVWLKNLEGQLQSDDYGKDLTSVNILLKKHQMLE 1464
Query: 4249 TEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKK 4428
+M + + + L + + V + LQ PL+ RR+ L K
Sbjct: 1465 HQMEVREKEVQSLQSQALALSQEDAG-LTEVDGQQRRVTDNFSNLQEPLNLRRQRLLASK 1523
Query: 4429 AAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQIC 4608
A QF RD++DE LW+ ER+ LA + + G+ LP L K Q L EI H+P I+ I
Sbjct: 1524 EAHQFNRDLEDEILWVKERMPLATSTDHGKDLPTVQLLIKKNQTLQKEIQGHQPRIDDIH 1583
Query: 4609 NNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEA 4788
+ E+++ EL+ W L R L E+ +A QF D EAEA
Sbjct: 1584 RRSKTQSQVDGERQSVQEERLCELQDLWSHLIAETDKRHTRLIEANRAQQFYADAAEAEA 1643
Query: 4789 WMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLT 4968
WM EQEL+M+ +E+ KDE S +KKH+ L+ ++ +A TI LA + V ++P +
Sbjct: 1644 WMGEQELHMLSEEKAKDEQSALVMLKKHQSLEQALEDYAQTIHQLANSSRLMVNSENPES 1703
Query: 4969 EQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQEN 5148
E+I +RQAQ++KLYAGL+D L RE+DDL QWIA++EVVAGS E
Sbjct: 1704 ERITLRQAQVDKLYAGLKDLAEERRGQLQESLRLTQLKREVDDLEQWIAEREVVAGSHEL 1763
Query: 5149 GQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEA 5328
GQDYEHV ML+++F++FARDT IG ERV N D LI GH + +IA WKD LNEA
Sbjct: 1764 GQDYEHVTMLRDKFREFARDTSTIGQERVDGVNALADDLIESGHIENISIAEWKDGLNEA 1823
Query: 5329 WENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKH 5508
W +LLEL+DTR Q+L AS LH+F+ D + L RI EK +P DLGRD + V L R+H
Sbjct: 1824 WADLLELIDTRTQMLAASYELHRFHQDAMEVLGRIKEKREGLPSDLGRDLNKVQHLHRQH 1883
Query: 5509 QNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSR 5688
+ DI A+ QV Q++ DAA L+ YAG+KA DI E V+ AW L AR
Sbjct: 1884 NTFENDIQALSGQVNQVQDDAARLQKAYAGEKADDIHRSEHAVISAWEGLLEAGQARRVL 1943
Query: 5689 LMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREEN 5868
L+DT + F+F NMVRDL+LWMD V ++++ + P+DVS L++ NHQ +K+EI+ R ++
Sbjct: 1944 LVDTVEKFRFFNMVRDLMLWMDGVNLQIDAHDSPRDVSSAGLVIANHQDIKSEIETRADS 2003
Query: 5869 FNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDA 6048
F ACI +G LLN HYAS EI +KL +L +R ++ ++W+D+ ++LQ++LEV QF RDA
Sbjct: 2004 FTACIEMGNTLLNNNHYASDEIREKLKQLQEKREKIDKKWQDKMDHLQIVLEVLQFGRDA 2063
Query: 6049 AVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKE 6228
+AESWL QEP + + E G N++E LIK+HEAFEK A E+RF+ LEKLTT E +E
Sbjct: 2064 YIAESWLAGQEPLVRAAELGANVDEVESLIKRHEAFEKLAAGWEDRFVLLEKLTTLEEQE 2123
Query: 6229 TQHREEETAKRRGP 6270
Q R EE + R P
Sbjct: 2124 MQRRREEEERARRP 2137
Score = 357 bits (915), Expect = 3e-96
Identities = 435/2071 (21%), Positives = 835/2071 (40%), Gaps = 70/2071 (3%)
Frame = +1
Query: 715 AEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKM---INRYET 885
A + V P E +I+ + + K + + R NEL+ +K+ R++
Sbjct: 413 ANNQKVYMPKEGKLISDINKAWERLEKAEHERELALR-----NELIRQEKLEMLAARFDR 467
Query: 886 LSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTL 1065
++ W++ +L+++ +F NL V+ + T + ++ ++ + L
Sbjct: 468 KAAMRETWLSENQRLVSQDNFGTNLGAVEAATRKHEAIET-DIGAYWERVAAVQAVAREL 526
Query: 1066 QSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNR 1245
++ + +R R+ L R W+ L++ R +E L L++L
Sbjct: 527 EAEGYHDVRRILARRDNVL-----RLWEYLKELLAAR----RERLNAHRDLQRLFQ---- 573
Query: 1246 KAEMRET--WLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXX 1419
EMR W+ + + + + G L V +KH +E D A ER
Sbjct: 574 --EMRYIMDWMGDMKGRLQSPDSGKHLHDVLDLLQKHTLVEADSSAQAERIKAVQGAAQR 631
Query: 1420 XXXXNYH----DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXX 1587
+ ++E+ + + RR +LE S + +
Sbjct: 632 FTSYEQAYKPCEPGLVSEKVDLLGQAYEELGQLAVKRREQLEDSRRLWQFLWDVGEEAAW 691
Query: 1588 XXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGS 1767
+ L S D G L LL KH ++ ++NSIA + +G G+
Sbjct: 692 IREQEQILASGDCGRDLTSALHLLSKHEAFRDEMAARYGPLSNSIAVGEALIK-EGHFGA 750
Query: 1768 GYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQ 1947
+ ER + ++ ++ L + + R++ L+++ L QF D ++E I E +
Sbjct: 751 P-------EVRERIEDIRGQWSHLEETSQLREQSLKESVALHQFQTDANDMEAWIMETFR 803
Query: 1948 VLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRL 2127
+SS + G D + L K + E ++ +D L + L + + RL
Sbjct: 804 QVSSQEVGHDEFSTQTLARKQREIEEEIKSHRPLIDSLHEQAQALPQAYV-NFPEVDGRL 862
Query: 2128 AEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTV 2307
I +L+ LS +R++ L G + Y+ F++A ++ + + + ++ +
Sbjct: 863 PAIEQRYEELESLSVARRQALEGALALYRMFSEAGACLVWVEEKEQRLHGMEIPTKLEDL 922
Query: 2308 QLLLKKHDDVHDELQNFDQHIKVLHAKAESL-PQEAREHPDIRQRLDTTLKQKAELENLS 2484
+++ ++ + + E+ N + ++ KAE L ++ I Q D + E E L+
Sbjct: 923 EVVQQRFETLEPEMNNLGARVTYVNQKAEQLLSSDSCNKDQIHQTRDQLNDRWKEFEQLA 982
Query: 2485 QLRKQRLIDALSLYKLYSDADSVESWIDEKGKLL-ATLVPGRDIEEVEIMKHRFDTLEQD 2661
+KQ L AL++ + + + +++W+ EK K++ +T G D+ V ++ + +E+D
Sbjct: 983 GQKKQDLESALNIQNYHLECNEIQTWMKEKTKVIESTQGLGNDLAGVMALQRKLTGMERD 1042
Query: 2662 MKNQEAKVTNVNDLARQLLNVEHPN-SDDILHRQNKLNARWAQLRDMVDQKRNELERAHR 2838
++ + K+ ++ + A +L EHP+ + +I R ++ W L D + ++ L A +
Sbjct: 1043 LEAIQGKLDDLRNEAEKLAR-EHPDQAGEIQGRLTEIQEVWEDLNDTMKRREESLGEASK 1101
Query: 2839 LETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLH 3018
L+ F D + TW+ +T+ S+ + L L + ++ ++ + + +
Sbjct: 1102 LQGFLRDLDDFQTWLS-RTQTAVASEDIPTSLPEAESLLAQHESIKNEVDNYKEDYEKMR 1160
Query: 3019 KEADDIER-ERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQ 3195
+++ + + + + + ++ + W L + + L +A D Q FLRD +
Sbjct: 1161 AVGEEVTQGQTDAQHMFLAQRLQALDTGWHELRRMWENRHSLLAQAFDFQTFLRDAKQAE 1220
Query: 3196 AWLTATQRQVASEEEPQSLAEAEQLLNQHA-------AIREEIDGYAEDYKKM----RAM 3342
+L + + ++ E P SL AE+ + +H A E+I+ E +++ A
Sbjct: 1221 TFLNSQEYVLSHTEMPTSLQGAEEAIKKHEDFLTTTEASEEKINSVVESGRRLINDCNAN 1280
Query: 3343 GDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVM 3522
D++ Q++ D L + + E L ++ DNR+ LQ FL+D ++ +
Sbjct: 1281 SDKI-QEKVDS---ILERHRKNKEAANELLAKLKDNRE--------LQHFLQDGQELTLW 1328
Query: 3523 LSQQENYLAKDDIPQSLEQAEN---QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHY 3693
++ E L D+ S ++A N + ++HQ F+ + +N + + + G L +
Sbjct: 1329 IN--EKMLTAQDM--SYDEARNLHSKWQKHQAFMAELASNKDWLDKIDKEGQALVAEKPE 1384
Query: 3694 AADKIHKKARNI----DERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIR 3861
+ + +++ +E G + KAQ L DA + F C L W++ +
Sbjct: 1385 LKPVVEQTLQDLQRQWEELEGTTQTKAQ----CLFDANRAELFTQSCSALDVWLKNLEGQ 1440
Query: 3862 AQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIE 4038
Q + Y +D ++ +HQ + ++ ++ + L+ A+ L + +D Q
Sbjct: 1441 LQSDDYGKDLTSVNILLKKHQMLEHQMEVREKEVQSLQSQALALSQEDAGLT-EVDGQQR 1499
Query: 4039 ELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVN 4218
+ + L++ + Q+L + + + + D W + T D DL TV
Sbjct: 1500 RVTDNFSNLQEPLNLRRQRLLASKEAHQFNRDLEDEILWVKERMPLATSTDHGKDLPTVQ 1559
Query: 4219 VAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA-VQEQLQRLQAPL 4395
+ ++K ++ E+ ID E ++++ RL +Q+ L A
Sbjct: 1560 LLIKKNQTLQKEIQGHQPRIDDIHRRSKTQSQVD-GERQSVQEERLCELQDLWSHLIAET 1618
Query: 4396 DDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEI 4575
D R L A QF D + + W+ E+ + ++ + + K Q L +
Sbjct: 1619 DKRHTRLIEANRAQQFYADAAEAEAWMGEQELHMLSEEKAKDEQSALVMLKKHQSLEQAL 1678
Query: 4576 DNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAH 4755
+++ I+Q+ N+ + +++ + + ++ + LK+ ++R+G L ES +
Sbjct: 1679 EDYAQTIHQLANSSRLMVNSENPESERITLRQAQVDKLYAGLKDLAEERRGQLQESLRLT 1738
Query: 4756 QFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKA 4935
Q + + E W++E+E+ E G+D +E + DKF + R +T
Sbjct: 1739 QLKREVDDLEQWIAEREVVAGSHELGQD----------YEHVTMLRDKFREFARDTSTIG 1788
Query: 4936 HKFVEEKSPLTEQI----QVRQAQIEKLYAGLQ----DXXXXXXXXXXXXXXXYALHREI 5091
+ V+ + L + + + I + GL D Y LHR
Sbjct: 1789 QERVDGVNALADDLIESGHIENISIAEWKDGLNEAWADLLELIDTRTQMLAASYELHRFH 1848
Query: 5092 DDLLQWIAD-KEVVAGSQEN-GQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTL 5265
D ++ + KE G + G+D VQ L + F D + + + +D
Sbjct: 1849 QDAMEVLGRIKEKREGLPSDLGRDLNKVQHLHRQHNTFENDIQALSGQVNQVQDDAARLQ 1908
Query: 5266 IGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKT 5445
+ A I + ++ AWE LLE R +L + +F++ RD L M+
Sbjct: 1909 KAYAGEKADDIHRSEHAVISAWEGLLEAGQARRVLLVDTVEKFRFFNMVRD-LMLWMDGV 1967
Query: 5446 HAMPD--DLGRDSSSVGALSRKHQNYLKDIAAIGEQ-VAQIERDAAELRDG-YAGDKALD 5613
+ D D RD SS G + HQ+ +I + A IE L + YA D+
Sbjct: 1968 NLQIDAHDSPRDVSSAGLVIANHQDIKSEIETRADSFTACIEMGNTLLNNNHYASDEI-- 2025
Query: 5614 IGSRESEVVKAWRHLRGLCDARTSRLMDTSDL-FKFMNMVRDLLL---WMDEVKREMNSQ 5781
E +K + R D + MD + + + RD + W+ + + +
Sbjct: 2026 -----REKLKQLQEKREKIDKKWQDKMDHLQIVLEVLQFGRDAYIAESWLAGQEPLVRAA 2080
Query: 5782 ERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTT 5961
E +V VE L+ H++ + E+ F L KLTT
Sbjct: 2081 ELGANVDEVESLIKRHEAFEKLAAGWEDRFVL----------------------LEKLTT 2118
Query: 5962 -ERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEET--IK 6132
E EM RR E+ E + AE + E + I R E+
Sbjct: 2119 LEEQEMQRRREEE--------ERARRPPTPPPAEEAVDMTESH-IHDSAARPCEQARLFP 2169
Query: 6133 LIKKHEAFE-------KSAFAQEERFLALEKLTTFEL-KETQHREEETAKRRGPAHIGSP 6288
K H+ F SA + + + F L Q E E+ GP
Sbjct: 2170 PSKFHDGFSHLPVIGCSSARSHPSSYRVFSRSPPFTLFLRPQGSESESVN--GPGRDSGL 2227
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
+ S A + + + EA EG L RK ES +KAA RSW+ +Y VLR+ L F
Sbjct: 2228 ASSRLEASATLPNRGGAESEPEAMEGMLCRKQEMESHSKKAATRSWQNVYCVLRKGSLGF 2287
Query: 6469 YKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K + HGE P++L VA DY+K+K+V LRL G EYLFQ E +M
Sbjct: 2288 YKDGKSASNGIPYHGEVPISLAEAVCEVAHDYKKRKHVFKLRLGDGKEYLFQAKDEAEMG 2347
Query: 6643 RWLTEL--QVATGQAQL----EEASRSQTLP 6717
W+ + V +G SR+ T+P
Sbjct: 2348 SWIRSILGSVPSGSGDSPGGPRVLSRAMTMP 2378
>gi|5902122|ref|NP_008877.1| spectrin, beta, non-erythrocytic 2 [Homo
sapiens]
gi|17367904|sp|O15020|SPCP_HUMAN Spectrin beta chain, brain 2
(Spectrin, non-erythroid beta chain 2) (Beta-III
spectrin)
gi|3550977|dbj|BAA32700.1| beta-spectrin III [Homo sapiens]
Length = 2390
Score = 1919 bits (4971), Expect = 0.0
Identities = 1001/2095 (47%), Positives = 1373/2095 (64%), Gaps = 4/2095 (0%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGK 216
D D+D D+SSARLFERSRIKALADERE VQKKTFTKWVNSHL RV+C+V DLY D+RDG+
Sbjct: 30 DSDWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGR 89
Query: 217 MLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLT 396
LLRLL VLSGE LPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLT
Sbjct: 90 NLLRLLEVLSGEILPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLT 149
Query: 397 LGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGL 576
LGL+WTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVNV NF+TSWRDGL
Sbjct: 150 LGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGL 209
Query: 577 AFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSI 756
AFNA++HKHRPDL+D+++L+K NA YNLQ+AF+ AE +LGL K LD EDVNVDQPDEKSI
Sbjct: 210 AFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSI 269
Query: 757 ITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLN 936
ITYV TYYHYF+K+K ++GKRIGKV++ ME ++++ +YE+L+S+LL+WI I LN
Sbjct: 270 ITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAERLVEKYESLASELLQWIEQTIVTLN 329
Query: 937 ERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREG 1116
+R N+L GVQ QL FN YRT EKPPKF EKG LEVLLFT+QS +RANNQ+ + PREG
Sbjct: 330 DRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREG 389
Query: 1117 KLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVS 1296
+LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLAARF+RKA MRETWL+ENQRLVS
Sbjct: 390 RLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVS 449
Query: 1297 QDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENV 1476
QDNFG +L++VEAA +KHEAIETDI AY R YHD +I R+ NV
Sbjct: 450 QDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAERYHDIKRIAARQHNV 509
Query: 1477 XXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDL 1656
ARR RL L++ +QK+F +K RL S+DLG HL VEDL
Sbjct: 510 ARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMEEMKGRLQSQDLGRHLAGVEDL 569
Query: 1657 LQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
LQ H L+E+DI + ERV A A RF NP G Y+P +P + ER L++ Y+
Sbjct: 570 LQLHELVEADIAVQAERVRAVSASALRFCNP----GKEYRPCDPQLVSERVAKLEQSYEA 625
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L +LAA R+ RLE+++RL +F W+V E E ++EQ+ +L+S DTGRD+ LL KH
Sbjct: 626 LCELAAARRARLEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGALRLLNKHTA 685
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
+ L G++L E PG+ R AE++ +L+ L+ R +RLA
Sbjct: 686 LRGEMSGRLGPLKLTLEQGQQLVAEGHPGASQASARAAELQAQWERLEALAEERAQRLAQ 745
Query: 2197 GVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKV 2376
YQF DA+D++ +L D LR++SS ++G DE + Q L ++H + +E+++ +
Sbjct: 746 AASLYQFQADANDMEAWLVDALRLVSSPELGHDEFSTQALARQHRALEEEIRSHRPTLDA 805
Query: 2377 LHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVE 2556
L +A +LP P+++ R+ T + EL+ + R + L AL+LY + S+A +
Sbjct: 806 LREQAAALPPTLSRTPEVQGRVPTLERHYEELQARAGERARALEAALALYTMLSEAGACG 865
Query: 2557 SWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN 2736
W++EK + L L +E++E+++ RF+TLE +M A++T VND+A QLL P
Sbjct: 866 LWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNTLAAQITAVNDIAEQLLKANPPG 925
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
D I++ Q +LN RW Q R + D K+ L A ++ + ++C ET W+ +KT+V+E +
Sbjct: 926 KDRIVNTQEQLNHRWQQFRRLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQ 985
Query: 2917 ALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQ 3096
L NDL+GV+ LQR+L+ ERDL AI A++ L +EA+ + P +A AI ++ +
Sbjct: 986 GLGNDLAGVLALQRKLAGTERDLEAIAARVGELTREANALAAGHPAQAVAINARLREVQT 1045
Query: 3097 VWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLN 3276
W+ L +R E L EA LQ FLR LD FQAWL TQ VASEE P +L EAE LL
Sbjct: 1046 GWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLA 1105
Query: 3277 QHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQ 3456
QHAA+R E++ +Y ++RA+G+ VT+DQ DPQ +FLRQRL L GWEEL RMW++RQ
Sbjct: 1106 QHAALRGEVERAQSEYSRLRALGEEVTRDQADPQCLFLRQRLEALGTGWEELGRMWESRQ 1165
Query: 3457 HLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAND 3636
L+Q Q FLRDA+QAE +LS QE L+ ++P +L+ A+ +K+ +DF++TMDAN
Sbjct: 1166 GRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTLQAADAAIKKLEDFMSTMDANG 1225
Query: 3637 EKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLS 3816
E+I + G QL +G+ ADKI +KA +I+ R N++ AQ+ L +L+D Q FL
Sbjct: 1226 ERIHGLLEAGRQLVSEGNIHADKIREKADSIERRHKKNQDAAQQFLGRLRDNREQQHFLQ 1285
Query: 3817 DCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
DC EL+ WI+EKM+ AQD +Y +A+ + +K+ +HQAF +ELAANK+ LD++ L
Sbjct: 1286 DCHELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTL 1345
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENE 4176
+KPE + ++ +L +WDELE TT+ K + LFDANR +L+ QS ++ W L+ +
Sbjct: 1346 EKPELKALVSEKLRDLHRRWDELETTTQAKARSLFDANRAELFAQSCCALESWLESLQAQ 1405
Query: 4177 MTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ +D DLT+VN+ ++KQ ++E EM + + ++ E + R
Sbjct: 1406 LHSDDYGKDLTSVNILLKKQQMLEWEMAVREKEVEAIQAQAKALAQEDQGAGEVERTSR- 1464
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
AV+E+ + L P+ +R + L+ + QF RDV+DE LW++ERL +A + G+ LP
Sbjct: 1465 AVEEKFRALCQPMRERCRRLQASREQHQFHRDVEDEILWVTERLPMASSMEHGKDLPSVQ 1524
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVK 4716
L K Q L EI HEP I + + L A GP ++ EL+ W+ L ++
Sbjct: 1525 LLMKKNQTLQKEIQGHEPRIADLRERQRAL--GAAAAGP----ELAELQEMWKRLGHELE 1578
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
R L ++ +A QF D EAEAWM EQEL+MM E+ KDE S + ++KKH+ L+ +
Sbjct: 1579 LRGKRLEDALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALA 1638
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
+A TI LA + ++ + P + +I +RQAQ++KLYAGL++
Sbjct: 1639 DYAQTIHQLAASSQDMIDHEHPESTRISIRQAQVDKLYAGLKELAGERRERLQEHLRLCQ 1698
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
L RE+DDL QWI ++EVVA S E GQDYEHV ML+++F++F+RDT IG ERV +AN
Sbjct: 1699 LRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALA 1758
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIM 5436
+ LI GH T+A WKDSLNEAW +LLEL+DTR Q+L A+ L +F H R L+R+
Sbjct: 1759 NGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQ 1818
Query: 5437 EKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDI 5616
K +PD GRD ++ AL R+H Y DI A+ QV Q++ D L+ YAGDKA +I
Sbjct: 1819 HKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSPQVQQVQDDGHRLQKAYAGDKAEEI 1878
Query: 5617 GSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKD 5796
G V +AW L+G AR L+DT+D F+F VR+L+LWMDEV +M++QERP+D
Sbjct: 1879 GRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDEVNLQMDAQERPRD 1938
Query: 5797 VSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEM 5976
VS +L++ N Q +KAEI+AR + F++CI +G++LL R HYA+ EI +KL +L R E
Sbjct: 1939 VSSADLVIKNQQGIKAEIEARADRFSSCIDMGKELLARSHYAAEEISEKLSQLQARRQET 1998
Query: 5977 MRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+W+++ ++LQL+LEV F RDA +AE+WL +QEP + S E G ++E LIK+HEAF
Sbjct: 1999 AEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAF 2058
Query: 6157 EKSAFAQEERFLALEKLTTFELKETQH---REEETAKRRGPAHIGSPSRSTPAAE 6312
+KSA A EERF ALEKLT E +E + REEE +++ PA P+ S P +
Sbjct: 2059 QKSAVAWEERFCALEKLTALEEREKERKRKREEEERRKQPPA--PEPTASVPPGD 2111
Score = 103 bits (258), Expect = 4e-20
Identities = 63/152 (41%), Positives = 80/152 (52%), Gaps = 4/152 (2%)
Frame = +1
Query: 6238 REEETAKRRGPAHIGSP-SRSTPAAETS-FGAQDDGAKQGEAFEGTLIRKHTYESLDRKA 6411
R E + RGPA P SRST +A + + E EG L RK E+ +KA
Sbjct: 2179 RGERQTRTRGPAPSAMPQSRSTESAHAATLPPRGPEPSAQEQMEGMLCRKQEMEAFGKKA 2238
Query: 6412 ANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSL 6585
ANRSW+ +Y VLR+ L FYKD K V HGE P++L +VA DY+K+K+V L
Sbjct: 2239 ANRSWQNVYCVLRRGSLGFYKDAKAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKL 2298
Query: 6586 RLPIGAEYLFQCGSEEDMQRWLTELQVATGQA 6681
L G EYLFQ E +M WL + A A
Sbjct: 2299 GLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 2330
>gi|17367415|sp|Q9QWN8|SPCP_RAT Spectrin beta chain, brain 2
(Spectrin, non-erythroid beta chain 2) (Beta-III
spectrin) (SPNB-3) (Beta SpIII sigma 1) (Spectrin-like
protein GTRAP41)
gi|3550975|dbj|BAA32699.1| beta-spectrin III [Rattus norvegicus]
Length = 2388
Score = 1916 bits (4963), Expect = 0.0
Identities = 1006/2113 (47%), Positives = 1381/2113 (64%), Gaps = 3/2113 (0%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGK 216
D D+D D+SSARLFERSRIKALADERE VQKKTFTKWVNSHL RV+C+V DLY D+RDG+
Sbjct: 30 DSDWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGR 89
Query: 217 MLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLT 396
LLRLL VLSGE LPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLT
Sbjct: 90 NLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLT 149
Query: 397 LGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGL 576
LGL+WTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVNV NF+TSWRDGL
Sbjct: 150 LGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGL 209
Query: 577 AFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSI 756
AFNA++HKHRPDL+D+++L+K NA YNLQ+AF+ AE +LGL K LD EDVNVDQPDEKSI
Sbjct: 210 AFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSI 269
Query: 757 ITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLN 936
ITYV TYYHYF+K+K ++GKRIGKV++ ME + ++ +YE+L+S+LL+WI I LN
Sbjct: 270 ITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAEHLVEKYESLASELLQWIEQTIVTLN 329
Query: 937 ERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREG 1116
+R N+L GVQ QL FN YRT EKPPKF EKG LEVLLFT+QS +RANNQ+ + PREG
Sbjct: 330 DRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREG 389
Query: 1117 KLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVS 1296
+LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLAARF+RKA MRETWL+ENQRLVS
Sbjct: 390 RLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVS 449
Query: 1297 QDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENV 1476
QDNFG +L++VEAA +KHEAIETDI AY R +YHD +I R+ NV
Sbjct: 450 QDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAEHYHDIKRIAARQNNV 509
Query: 1477 XXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDL 1656
ARR RL L++ +QK+F +K RL S+DLG HL VEDL
Sbjct: 510 ARLWDFLREMVAARRERLLLNLELQKVFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDL 569
Query: 1657 LQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
LQ H L+E+DI + ERV A A RF +P G Y+P +P + ER L++ Y+
Sbjct: 570 LQLHELVEADIAVQAERVRAVSASALRFCDP----GKEYRPCDPQLVSERVATLEQSYEA 625
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L +LAA R+ RLE+++RL +F W+V E E ++EQ+ +L+S +TGRD+ V LL KH
Sbjct: 626 LCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVLRLLNKHTA 685
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
+ L G++L E PG++ R AE++ +L+ L+ R +RLA
Sbjct: 686 LRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERAQRLAQ 745
Query: 2197 GVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKV 2376
YQF DA+D++ +L D LR++SS +VG DE + Q L ++H + +E++ +
Sbjct: 746 AASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDA 805
Query: 2377 LHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVE 2556
L +A +LP P+++ R+ T + EL+ + R + L AL+ Y + S+A +
Sbjct: 806 LREQAAALPPALSHTPEVQGRVPTLEQHYEELQARAGERARALEAALAFYTMLSEAGACG 865
Query: 2557 SWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN 2736
W++EK + L L +E++E+++ RF+TLE +M A+VT V+D+A QLL P
Sbjct: 866 LWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVSDIAEQLLKASPPG 925
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
D I+ Q +LN RW Q R + D K+ L A ++ + ++C ET W+ +KT+V+E +
Sbjct: 926 KDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQ 985
Query: 2917 ALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQ 3096
L NDL+GV+ LQR+L+ ERDL AI A++ L +EA+ + P +A AI + +
Sbjct: 986 DLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAINTRLGEVQT 1045
Query: 3097 VWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLN 3276
W+ L +R E L EA LQ FLR LD FQAWL TQ VASEE P +L EAE LL
Sbjct: 1046 GWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLA 1105
Query: 3277 QHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQ 3456
QHAA+R E++ +Y ++R +G+ VT+DQ DPQ +FLRQRL L GWEEL RMW++RQ
Sbjct: 1106 QHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRLEALGTGWEELGRMWESRQ 1165
Query: 3457 HLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAND 3636
L+Q Q FLRDA+QAE +LS QE +L+ ++P +L+ A+ +K+ +DF++TMDAN
Sbjct: 1166 GRLAQAHGFQGFLRDARQAEGVLSSQEYFLSHTEMPGTLQAADAAIKKLEDFMSTMDANG 1225
Query: 3637 EKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLS 3816
E+IR + G QL G+ A+KI +KA +I++R N+E Q++L +L+D Q FL
Sbjct: 1226 ERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQ 1285
Query: 3817 DCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
DC EL+ WI+EKM+ AQD +Y +A+ + +K+ +HQAF +ELAANK+ LD++ L
Sbjct: 1286 DCQELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTL 1345
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENE 4176
+KPE + ++E+L +WDELE TT+ K + LFDANR +L+ QS + ++ W L+ +
Sbjct: 1346 EKPELKVLVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQ 1405
Query: 4177 MTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ +D DLT+VN+ ++KQ ++E EM + + ++ E + R
Sbjct: 1406 LHSDDYGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAKALAQEDQSAGEVERTSR- 1464
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
AV+E+ + L P+ DR + L+ + QF RDV+DE LW++ERL +A + G+ LP
Sbjct: 1465 AVEEKFRALCQPMKDRCRRLQASREQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQ 1524
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVK 4716
L K Q L EI HEP I + + L A GP ++ EL+ W+ L ++
Sbjct: 1525 LLMKKNQTLQKEIQGHEPRIADLKERQRTL--GTAAAGP----ELAELQEMWKRLSHELE 1578
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
R L E+ +A QF D EAEAWM EQEL+MM E+ KDE S + ++KKH+ L+ +
Sbjct: 1579 LRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALA 1638
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
+A TI+ LA + ++ + P + ++ +RQAQ++KLYAGL++
Sbjct: 1639 DYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQ 1698
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
L RE+DDL QWI ++EVVA S E GQDYEHV ML+++F++F+RDT IG ERV +AN
Sbjct: 1699 LRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALA 1758
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIM 5436
+ LI GH T+A WKDSLNEAW +LLEL+DTR Q+L A+ L +F H R L+R+
Sbjct: 1759 NGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQ 1818
Query: 5437 EKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDI 5616
K +PD GRD ++ AL R+H Y DI A+ QV Q++ D L+ YAGDKA +I
Sbjct: 1819 HKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEI 1878
Query: 5617 GSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKD 5796
G V +AW L+G AR L+DT+D F+F VR+L+LWMD + +M++QERP+D
Sbjct: 1879 GRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRD 1938
Query: 5797 VSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEM 5976
VS +L++ N Q +KAEI+AR + F+ACI +G++LL R HYA+ EI +KL +L + R E
Sbjct: 1939 VSSADLVIKNQQGIKAEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQET 1998
Query: 5977 MRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+W+++ ++LQL+LEV F RDA +AE+WL +QEP + S E G ++E LIK+HEAF
Sbjct: 1999 AEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAF 2058
Query: 6157 EKSAFAQEERFLALEKLTTFELKET-QHREEETAKRRGPAHIGSPSRSTPAAETSFGAQD 6333
+KSA A EERF ALEKLT E +E Q R+ E +RR P S P A G+
Sbjct: 2059 QKSAVAWEERFSALEKLTALEERENEQKRKREEEERR-----KQPPTSEPMASQPEGSLV 2113
Query: 6334 DGAK-QGEAFEGT 6369
DG + A++GT
Sbjct: 2114 DGQRVLDTAWDGT 2126
Score = 320 bits (820), Expect = 3e-85
Identities = 406/1903 (21%), Positives = 753/1903 (39%), Gaps = 52/1903 (2%)
Frame = +1
Query: 1129 DINRAWQSLEK--AEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQD 1302
++ R W L + A L+L EL Q+ + L + AEM+ RL SQD
Sbjct: 508 NVARLWDFLREMVAARRERLLLNLEL--QKVFQDLLYLMDWMAEMKG-------RLQSQD 558
Query: 1303 NFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYH----DQAKINERKE 1470
G L+ VE + HE +E DI ER D ++ER
Sbjct: 559 -LGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCDPGKEYRPCDPQLVSERVA 617
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+ RR RLE S + + + L S + G L V
Sbjct: 618 TLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVL 677
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
LL KH L +++ + ++ Q Q+ P + R+ LQ ++
Sbjct: 678 RLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGAN--------QASTRAAELQAQW 729
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKH 2010
+ L LA ER +RL L QF D ++E + + +++SS + G D + L +H
Sbjct: 730 ERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQH 789
Query: 2011 KNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERL 2190
+ E +R LD L L ++ + + R+ + + +L+ + R L
Sbjct: 790 RALEEEIRAHRPTLDALREQAAALPP-ALSHTPEVQGRVPTLEQHYEELQARAGERARAL 848
Query: 2191 AGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHI 2370
+ +Y ++A ++ + + ++ + + ++++ ++ + + E+ +
Sbjct: 849 EAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARV 908
Query: 2371 KVLHAKAESLPQEAREHPDIRQRLDTTLKQK-AELENLSQLRKQRLIDALSLYKLYSDAD 2547
+ AE L + + D L Q+ + +L+ +K L ALS+ + +
Sbjct: 909 TAVSDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECT 968
Query: 2548 SVESWIDEKGKLL-ATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNV 2724
++W+ EK K++ +T G D+ V ++ + E+D++ A+V + A L
Sbjct: 969 ETQAWMREKTKVIESTQDLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAG 1028
Query: 2725 EHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVL 2904
+ I R ++ W LR + ++ L A RL+ F + W+ +T+
Sbjct: 1029 HPAQAPAINTRLGEVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWL-GRTQTA 1087
Query: 2905 EDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQ-EAQAIREDI 3081
S+ L L + + + ++ Q++ L +++ R++ + +R+ +
Sbjct: 1088 VASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRL 1147
Query: 3082 KRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEA 3261
+ + W+ L + + +L +A Q FLRD + L++ + ++ E P +L A
Sbjct: 1148 EALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYFLSHTEMPGTLQAA 1207
Query: 3262 -------EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 3420
E ++ A E I G E +++ + G+ + ++ + + +R QE
Sbjct: 1208 DAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGN-IHAEKIQEKADSIEKRHRKNQEA 1266
Query: 3421 WEELQ-RMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN--- 3588
++L R+ DNR+ Q FL+D ++ ++ + E L D+ S ++A N
Sbjct: 1267 VQQLLGRLRDNREQ--------QHFLQDCQELKLWID--EKMLTAQDV--SYDEARNLHT 1314
Query: 3589 QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
+ ++HQ F+ + AN + + V G +L + + +K ++ R Q
Sbjct: 1315 KWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVLVSEKLEDLHRRWDELETTTQA 1374
Query: 3769 VLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAA 3945
+ L DA + F C L W+E + + Y +D ++ + Q + E+A
Sbjct: 1375 KARSLFDANRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAV 1434
Query: 3946 NKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLY 4125
++ ++ ++ A L + + G ++ + ++ L + +++ ++L + Q +
Sbjct: 1435 REKEVEAIQAQAKALAQED-QSAGEVERTSRAVEEKFRALCQPMKDRCRRLQASREQHQF 1493
Query: 4126 VQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHI-DXXXXXXX 4302
+ + D W T+ + + DL +V + M+K ++ E+ I D
Sbjct: 1494 HRDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLKERQRT 1553
Query: 4303 XXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISE 4482
EL + QE +RL L+ R K LE A QF RD + + W+ E
Sbjct: 1554 LGTAAAGPELAEL-------QEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGE 1606
Query: 4483 RLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFE 4662
+ + Q + K Q+L + ++ I Q+ + Q++ID H
Sbjct: 1607 QELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLT 1666
Query: 4663 KKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDE 4842
+ ++ + LKE +R+ L E + Q + + E W+ E+E+ E G+D
Sbjct: 1667 IRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQD- 1725
Query: 4843 FSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQI----QVRQAQI---- 4998
+E + DKF + R +T + V+ + L + +A +
Sbjct: 1726 ---------YEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWK 1776
Query: 4999 EKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQE----NGQDYEH 5166
+ L D Y L R + Q +A V Q+ G+D
Sbjct: 1777 DSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALA--RVQHKQQQLPDGTGRDLNA 1834
Query: 5167 VQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLE 5346
+ LQ R + D + + ++ +DG + A I ++ EAW L
Sbjct: 1835 AEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEIGRHMQAVAEAWAQLQG 1894
Query: 5347 LMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD--DLGRDSSSVGALSRKHQNYL 5520
R Q+L + +F+ R+ L M+ + D + RD SS + + Q
Sbjct: 1895 SSAARRQLLLDTTDKFRFFKAVRE-LMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIK 1953
Query: 5521 KDIAAIGEQVAQIERDAAEL--RDGYAGD----KALDIGSRESEVVKAWRHLRGLCDART 5682
+I A ++ + EL R+ YA + K + SR E + W+ +
Sbjct: 1954 AEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQETAEKWQE-------KM 2006
Query: 5683 SRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDARE 5862
L ++ F W+ + + S E V VE L+ H++ + A E
Sbjct: 2007 DWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWE 2066
Query: 5863 ENFNACISLG--RDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
E F+A L + N + E E++ T+E M + E Q +L+
Sbjct: 2067 ERFSALEKLTALEERENEQKRKREEEERRKQPPTSE--PMASQPEGSLVDGQRVLDT--- 2121
Query: 6037 ARDAAVAESWLFAQEPYL----ISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
A D ++ Q P + E + L E +L + + + +E
Sbjct: 2122 AWDGTQSKLPPSTQAPSINGVCTDTESSQPLLEQQRLEQSNVPEGPGSGTGDE------- 2174
Query: 6205 LTTFELKETQHREEETAKRRGPAHIGSP-SRSTPAAETS-FGAQDDGAKQGEAFEGTLIR 6378
+ R E RGPA P SRS+ +A + A+ E EGTL R
Sbjct: 2175 -------SSGPRGERQTLPRGPAPSPMPQSRSSESAHVATLPARGAELSAQEQMEGTLCR 2227
Query: 6379 KHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVAS 6552
K E+ ++KAANRSW+ +Y VLR+ L FYKD + V HGE P++L +VA
Sbjct: 2228 KQEMEAFNKKAANRSWQNVYCVLRRGSLGFYKDARAASAGVPYHGEVPVSLARAQGSVAF 2287
Query: 6553 DYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQA 6681
DY+K+K+V L L G EYLFQ E +M WL + A A
Sbjct: 2288 DYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 2330
>gi|9507135|ref|NP_062040.1| beta-spectrin 3 [Rattus norvegicus]
gi|7441357|pir||JE0271 beta spectrin, beta_SpIII_sigma1 - rat
gi|3452553|dbj|BAA32473.1| brain beta 3 spectrin [Rattus norvegicus]
Length = 2388
Score = 1910 bits (4947), Expect = 0.0
Identities = 1004/2113 (47%), Positives = 1378/2113 (64%), Gaps = 3/2113 (0%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGK 216
D D+D D+SSARLFERSRIKALADERE VQKKTFTKWVNSHL RV+C+V DLY D+RDG+
Sbjct: 30 DSDWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGR 89
Query: 217 MLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLT 396
LLRLL VLSGE LPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLT
Sbjct: 90 NLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLT 149
Query: 397 LGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGL 576
LGL+WTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVNV NF+TSWRDGL
Sbjct: 150 LGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGL 209
Query: 577 AFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSI 756
AFNA++HKHRPDL+D+++L+K NA YNLQ+AF+ AE +LGL K LD EDVNVDQPDEKSI
Sbjct: 210 AFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSI 269
Query: 757 ITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLN 936
ITYV TYYHYF+K+K ++GKRIGKV++ ME + ++ +YE+L+S+LL+WI I LN
Sbjct: 270 ITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAEHLVEKYESLASELLQWIEQTIVTLN 329
Query: 937 ERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREG 1116
+R N+L GVQ QL FN YRT EKPPKF EKG LEVLLFT+QS +RANNQ+ + PREG
Sbjct: 330 DRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREG 389
Query: 1117 KLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVS 1296
+LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLAARF+RKA MRETWL+ENQRLVS
Sbjct: 390 RLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVS 449
Query: 1297 QDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENV 1476
QDNFG +L++VEAA +KHEAIETDI AY R +YHD +I R+ NV
Sbjct: 450 QDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAEHYHDIKRIAARQNNV 509
Query: 1477 XXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDL 1656
ARR RL L++ +QK+F +K RL S+DLG HL VEDL
Sbjct: 510 ARLWDFLREMVAARRERLLLNLELQKVFQDLLYFMDWMAEMKGRLQSQDLGKHLAGVEDL 569
Query: 1657 LQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
LQ H L+E+DI + ERV A A RF +P G Y+P +P + ER L++ Y+
Sbjct: 570 LQLHELVEADIAVQAERVRAVSASALRFCDP----GKEYRPCDPQLVSERVATLEQSYEA 625
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L +LAA R+ RLE+++RL +F W+V E E ++EQ+ +L+S +TGRD+ V LL KH
Sbjct: 626 LCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVLRLLNKHTA 685
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
+ L G++L E PG++ R AE++ +L+ L+ R +RLA
Sbjct: 686 LRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERAQRLAQ 745
Query: 2197 GVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKV 2376
YQF DA+D++ +L D LR++SS +VG DE + Q L ++H + +E++ +
Sbjct: 746 AASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDA 805
Query: 2377 LHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVE 2556
L +A +LP P+++ R+ T + EL+ + R + L AL+ Y + S+A +
Sbjct: 806 LREQAAALPPALSHTPEVQGRVPTLEQHYEELQARAGERARALEAALAFYTMLSEAGACG 865
Query: 2557 SWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN 2736
W++EK + L L +E++E+++ RF+TLE +M A+VT V+D+A QLL P
Sbjct: 866 LWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVSDIAEQLLKASPPG 925
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
D I+ Q +LN RW Q R + D K+ L A ++ + ++C ET W+ +KT+V+E +
Sbjct: 926 KDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQ 985
Query: 2917 ALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQ 3096
L NDL+GV+ LQR+L+ ERDL AI A++ L +EA+ + P +A AI + +
Sbjct: 986 DLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAINTRLGEVQT 1045
Query: 3097 VWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLN 3276
W+ L +R E L EA LQ FLR LD FQAWL TQ VASEE P +L EAE LL
Sbjct: 1046 GWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLA 1105
Query: 3277 QHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQ 3456
QHAA+R E++ +Y ++R +G+ VT+DQ DPQ +FLRQRL L GWE RMW++RQ
Sbjct: 1106 QHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRLEALGTGWEGAGRMWESRQ 1165
Query: 3457 HLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAND 3636
L+Q Q FLRDA+QAE +LS QE L+ ++P +L+ A+ +K+ +DF++TMDAN
Sbjct: 1166 GRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTLQAADAAIKKLEDFMSTMDANG 1225
Query: 3637 EKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLS 3816
E+IR + G QL G+ A+KI +KA +I++R N+E Q++L +L+D Q FL
Sbjct: 1226 ERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQ 1285
Query: 3817 DCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
DC EL+ WI+EKM+ AQD +Y +A+ + +K+ +HQAF +ELAANK+ LD++ L
Sbjct: 1286 DCQELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTL 1345
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENE 4176
+KPE + ++E+L +WDELE TT+ K + LFDANR +L+ QS + ++ W L+ +
Sbjct: 1346 EKPELKVLVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQ 1405
Query: 4177 MTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ +D DLT+VN+ ++KQ ++E EM + + ++ E + R
Sbjct: 1406 LHSDDYGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAKALAQEDQSAGEVERTSR- 1464
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
AV+E+ + L P+ DR + L+ + QF RDV+DE LW++ERL +A + G+ LP
Sbjct: 1465 AVEEKFRALCQPMKDRCRRLQASREQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQ 1524
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVK 4716
L K Q L EI HEP I + + L A GP ++ EL+ W+ L ++
Sbjct: 1525 LLMKKNQTLQKEIQGHEPRIADLKERQRTL--GTAAAGP----ELAELQEMWKRLSHELE 1578
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
R L E+ +A QF D EAEAWM EQEL+MM E+ KDE S + ++KKH+ L+ +
Sbjct: 1579 LRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALA 1638
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
+A TI+ LA + ++ + P + ++ +RQAQ++KLYAGL++
Sbjct: 1639 DYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQ 1698
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
L RE+DDL QWI ++EVVA S E GQDYEHV ML+++F++F+RDT IG ERV +AN
Sbjct: 1699 LRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALA 1758
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIM 5436
+ LI GH T+A WKDSLNEAW +LLEL+DTR Q+L A+ L +F H R L+R+
Sbjct: 1759 NGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQ 1818
Query: 5437 EKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDI 5616
K +PD GRD ++ AL R+H Y DI A+ QV Q++ D L+ YAGDKA +I
Sbjct: 1819 HKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEI 1878
Query: 5617 GSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKD 5796
G V +AW L+G AR L+DT+D F+F VR+L+LWMD + +M++QERP+D
Sbjct: 1879 GRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRD 1938
Query: 5797 VSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEM 5976
VS +L++ N Q +KAEI+AR + F+ACI +G++LL R HYA+ EI +KL +L + R E
Sbjct: 1939 VSSADLVIKNQQGIKAEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQET 1998
Query: 5977 MRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+W+++ ++LQL+LEV F RDA +AE+WL +QEP + S E G ++E LIK+HEAF
Sbjct: 1999 AEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAF 2058
Query: 6157 EKSAFAQEERFLALEKLTTFELKET-QHREEETAKRRGPAHIGSPSRSTPAAETSFGAQD 6333
+KSA A EERF ALEKLT E +E Q R+ E +RR P S P A G+
Sbjct: 2059 QKSAVAWEERFSALEKLTALEERENEQKRKREEEERR-----KQPPTSEPMASQPEGSLV 2113
Query: 6334 DGAK-QGEAFEGT 6369
DG + A++GT
Sbjct: 2114 DGQRVLDTAWDGT 2126
Score = 318 bits (814), Expect = 2e-84
Identities = 405/1903 (21%), Positives = 752/1903 (39%), Gaps = 52/1903 (2%)
Frame = +1
Query: 1129 DINRAWQSLEK--AEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQD 1302
++ R W L + A L+L EL Q+ + L + AEM+ RL SQD
Sbjct: 508 NVARLWDFLREMVAARRERLLLNLEL--QKVFQDLLYFMDWMAEMKG-------RLQSQD 558
Query: 1303 NFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYH----DQAKINERKE 1470
G L+ VE + HE +E DI ER D ++ER
Sbjct: 559 -LGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCDPGKEYRPCDPQLVSERVA 617
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+ RR RLE S + + + L S + G L V
Sbjct: 618 TLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVL 677
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
LL KH L +++ + ++ Q Q+ P + R+ LQ ++
Sbjct: 678 RLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGAN--------QASTRAAELQAQW 729
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKH 2010
+ L LA ER +RL L QF D ++E + + +++SS + G D + L +H
Sbjct: 730 ERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQH 789
Query: 2011 KNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERL 2190
+ E +R LD L L ++ + + R+ + + +L+ + R L
Sbjct: 790 RALEEEIRAHRPTLDALREQAAALPP-ALSHTPEVQGRVPTLEQHYEELQARAGERARAL 848
Query: 2191 AGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHI 2370
+ +Y ++A ++ + + ++ + + ++++ ++ + + E+ +
Sbjct: 849 EAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARV 908
Query: 2371 KVLHAKAESLPQEAREHPDIRQRLDTTLKQK-AELENLSQLRKQRLIDALSLYKLYSDAD 2547
+ AE L + + D L Q+ + +L+ +K L ALS+ + +
Sbjct: 909 TAVSDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECT 968
Query: 2548 SVESWIDEKGKLL-ATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNV 2724
++W+ EK K++ +T G D+ V ++ + E+D++ A+V + A L
Sbjct: 969 ETQAWMREKTKVIESTQDLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAG 1028
Query: 2725 EHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVL 2904
+ I R ++ W LR + ++ L A RL+ F + W+ +T+
Sbjct: 1029 HPAQAPAINTRLGEVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWL-GRTQTA 1087
Query: 2905 EDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQ-EAQAIREDI 3081
S+ L L + + + ++ Q++ L +++ R++ + +R+ +
Sbjct: 1088 VASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRL 1147
Query: 3082 KRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEA 3261
+ + W+ + + +L +A Q FLRD + L++ + ++ E P +L A
Sbjct: 1148 EALGTGWEGAGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTLQAA 1207
Query: 3262 -------EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG 3420
E ++ A E I G E +++ + G+ + ++ + + +R QE
Sbjct: 1208 DAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGN-IHAEKIQEKADSIEKRHRKNQEA 1266
Query: 3421 WEELQ-RMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN--- 3588
++L R+ DNR+ Q FL+D ++ ++ + E L D+ S ++A N
Sbjct: 1267 VQQLLGRLRDNREQ--------QHFLQDCQELKLWID--EKMLTAQDV--SYDEARNLHT 1314
Query: 3589 QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
+ ++HQ F+ + AN + + V G +L + + +K ++ R Q
Sbjct: 1315 KWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVLVSEKLEDLHRRWDELETTTQA 1374
Query: 3769 VLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAA 3945
+ L DA + F C L W+E + + Y +D ++ + Q + E+A
Sbjct: 1375 KARSLFDANRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAV 1434
Query: 3946 NKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLY 4125
++ ++ ++ A L + + G ++ + ++ L + +++ ++L + Q +
Sbjct: 1435 REKEVEAIQAQAKALAQED-QSAGEVERTSRAVEEKFRALCQPMKDRCRRLQASREQHQF 1493
Query: 4126 VQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHI-DXXXXXXX 4302
+ + D W T+ + + DL +V + M+K ++ E+ I D
Sbjct: 1494 HRDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLKERQRT 1553
Query: 4303 XXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISE 4482
EL + QE +RL L+ R K LE A QF RD + + W+ E
Sbjct: 1554 LGTAAAGPELAEL-------QEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGE 1606
Query: 4483 RLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFE 4662
+ + Q + K Q+L + ++ I Q+ + Q++ID H
Sbjct: 1607 QELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLT 1666
Query: 4663 KKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDE 4842
+ ++ + LKE +R+ L E + Q + + E W+ E+E+ E G+D
Sbjct: 1667 IRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQD- 1725
Query: 4843 FSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQI----QVRQAQI---- 4998
+E + DKF + R +T + V+ + L + +A +
Sbjct: 1726 ---------YEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAARATVAEWK 1776
Query: 4999 EKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQE----NGQDYEH 5166
+ L D Y L R + Q +A V Q+ G+D
Sbjct: 1777 DSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALA--RVQHKQQQLPDGTGRDLNA 1834
Query: 5167 VQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLE 5346
+ LQ R + D + + ++ +DG + A I ++ EAW L
Sbjct: 1835 AEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEIGRHMQAVAEAWAQLQG 1894
Query: 5347 LMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD--DLGRDSSSVGALSRKHQNYL 5520
R Q+L + +F+ R+ L M+ + D + RD SS + + Q
Sbjct: 1895 SSAARRQLLLDTTDKFRFFKAVRE-LMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIK 1953
Query: 5521 KDIAAIGEQVAQIERDAAEL--RDGYAGD----KALDIGSRESEVVKAWRHLRGLCDART 5682
+I A ++ + EL R+ YA + K + SR E + W+ +
Sbjct: 1954 AEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQETAEKWQE-------KM 2006
Query: 5683 SRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDARE 5862
L ++ F W+ + + S E V VE L+ H++ + A E
Sbjct: 2007 DWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWE 2066
Query: 5863 ENFNACISLG--RDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
E F+A L + N + E E++ T+E M + E Q +L+
Sbjct: 2067 ERFSALEKLTALEERENEQKRKREEEERRKQPPTSE--PMASQPEGSLVDGQRVLDT--- 2121
Query: 6037 ARDAAVAESWLFAQEPYL----ISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
A D ++ Q P + E + L E +L + + + +E
Sbjct: 2122 AWDGTQSKLPPSTQAPSINGVCTDTESSQPLLEQQRLEQSNVPEGPGSGTGDE------- 2174
Query: 6205 LTTFELKETQHREEETAKRRGPAHIGSP-SRSTPAAETS-FGAQDDGAKQGEAFEGTLIR 6378
+ R E RGPA P SRS+ +A + A+ E EGTL R
Sbjct: 2175 -------SSGPRGERQTLPRGPAPSPMPQSRSSESAHVATLPARGAELSAQEQMEGTLCR 2227
Query: 6379 KHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVAS 6552
K E+ ++KAANRSW+ +Y VLR+ L FYKD + V HGE P++L +VA
Sbjct: 2228 KQEMEAFNKKAANRSWQNVYCVLRRGSLGFYKDARAASAGVPYHGEVPVSLARAQGSVAF 2287
Query: 6553 DYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQA 6681
DY+K+K+V L L G EYLFQ E +M WL + A A
Sbjct: 2288 DYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 2330
>gi|11066461|gb|AAG28596.1| spectrin-like protein GTRAP41 [Rattus
norvegicus]
Length = 2388
Score = 1907 bits (4940), Expect = 0.0
Identities = 1003/2113 (47%), Positives = 1376/2113 (64%), Gaps = 3/2113 (0%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGK 216
D D+D D+SSARLFERSRIKALADERE VQKKTFTKWVNSHL RV+C+V DLY D+RDG+
Sbjct: 30 DSDWDNDSSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRVGDLYSDLRDGR 89
Query: 217 MLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLT 396
LLRLL VLSGE LPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLT
Sbjct: 90 NLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLT 149
Query: 397 LGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGL 576
LGL+WTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVNV NF+TSWRDGL
Sbjct: 150 LGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGL 209
Query: 577 AFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSI 756
AFNA++HKHRPDL+D+++L+K NA YNLQ+AF+ AE +LGL K LD EDVNVDQPDEKSI
Sbjct: 210 AFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKELGLTKLLDPEDVNVDQPDEKSI 269
Query: 757 ITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLN 936
ITYV TYYHYF+K+K ++GKRIGKV++ ME + ++ +YE+L+S+LL+WI I N
Sbjct: 270 ITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAEHLVEKYESLASELLQWIEQTIGTFN 329
Query: 937 ERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREG 1116
+R N+L GVQ QL FN YRT EKPPKF EKG LEVLLFT+QS +RANNQ+ + PREG
Sbjct: 330 DRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVLLFTIQSKLRANNQKVYTPREG 389
Query: 1117 KLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVS 1296
+LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLAARF+RKA MRETWL+ENQRLVS
Sbjct: 390 RLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAARFDRKAAMRETWLSENQRLVS 449
Query: 1297 QDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENV 1476
QDNFG +L++VEAA +KHEAIETDI AY R +YHD +I R+ NV
Sbjct: 450 QDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVAAELAAEHYHDIKRIAARQNNV 509
Query: 1477 XXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDL 1656
ARR RL L++ +QK+F +K RL S+DLG HL VEDL
Sbjct: 510 ARLWDFLREMVAARRERLLLNLELQKVFQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDL 569
Query: 1657 LQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
LQ H L+E+DI + ERV A A RF +P G Y+P P + ER L++ Y+
Sbjct: 570 LQLHELVEADIAVQAERVRAVSASALRFCDP----GKEYRPCGPQLVSERVATLEQSYEA 625
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L +LAA R+ RLE+++RL +F W+V E E ++EQ+ +L+S +TGRD+ V LL KH
Sbjct: 626 LCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRDLTGVLRLLNKHTA 685
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
+ L G++L E PG++ R AE++ +L+ L+ R +RLA
Sbjct: 686 LRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERAQRLAQ 745
Query: 2197 GVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKV 2376
YQF DA+D++ +L D LR++SS +VG DE + Q L ++H + +E++ +
Sbjct: 746 AASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRPTLDA 805
Query: 2377 LHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVE 2556
L +A +LP P+++ R+ T + EL+ + R + L AL+ Y + S+A +
Sbjct: 806 LREQAAALPPALSHTPEVQGRVPTLEQHYEELQARAGERARALEAALAFYTMLSEAGACG 865
Query: 2557 SWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN 2736
W++EK + L L +E+ E+++ RF+TLE +M A++T V+D+A QLL P
Sbjct: 866 LWVEEKEQWLNGLALPERLEDPEVVQQRFETLEPEMNALAARITAVSDIAEQLLKASPPG 925
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
D I+ Q +LN RW Q R + K+ L A ++ + ++C ET W+ +KT+V+E +
Sbjct: 926 KDRIIGTQEQLNQRWQQFRSLAGGKKAALTSALSIQNYHLECTETQAWMREKTKVIESTQ 985
Query: 2917 ALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQ 3096
L NDL+GV+ LQR+L+ ERDL AI A++ L +EA+ + P +A AI + +
Sbjct: 986 DLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHPAQAPAINTRLGEVQT 1045
Query: 3097 VWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLN 3276
W+ L +R E L EA LQ FLR LD FQAWL TQ VASEE P +L EAE LL
Sbjct: 1046 GWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVASEEGPATLPEAEALLA 1105
Query: 3277 QHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQ 3456
QHAA+R E++ +Y ++R +G+ VT+DQ DPQ +FLRQRL L GWEEL RMW++RQ
Sbjct: 1106 QHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRLEALGTGWEELGRMWESRQ 1165
Query: 3457 HLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAND 3636
L+Q Q FLRDA+QAE +LS QE L+ ++P +L+ A+ +K+ +DF++TMDAN
Sbjct: 1166 GRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTLQAADAAIKKLEDFMSTMDANG 1225
Query: 3637 EKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLS 3816
E+IR + G QL G+ A+KI +KA +I++R N+E Q++L +L+D Q FL
Sbjct: 1226 ERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQ 1285
Query: 3817 DCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
DC EL+ WI+EKM+ AQD +Y +A+ + +K+ +HQAF +ELAANK+ LD++ L
Sbjct: 1286 DCQELKLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTL 1345
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENE 4176
+KPE + ++E+L +WDELE TT+ K + LFDANR +L+ QS + ++ W L+ +
Sbjct: 1346 EKPELKVLVSEKLEDLHRRWDELETTTQAKARSLFDANRAELFAQSCSALESWLESLQAQ 1405
Query: 4177 MTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ +D DLT+VN+ ++KQ ++E EM + + ++ E + R
Sbjct: 1406 LHSDDYGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAKALAQEDQSAGEVERTSR- 1464
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
AV+E+ + L P+ DR + L+ + QF RDV+DE LW++ERL +A + G+ LP
Sbjct: 1465 AVEEKFRALCQPMKDRCRRLQASREQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQ 1524
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVK 4716
L K Q L EI HEP I + + L A GP ++ EL+ W+ L ++
Sbjct: 1525 LLMKKNQTLQKEIQGHEPRIADLKERQRTL--RTAAAGP----ELAELQEMWKRLSHELE 1578
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
R L E+ +A QF D EAEAWM EQEL+MM E+ KDE S + ++KKH+ L+ +
Sbjct: 1579 LRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALA 1638
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
+A TI+ LA + ++ + P + ++ +RQAQ++KLYAGL++
Sbjct: 1639 DYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQ 1698
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
L RE+DDL QWI ++EVVA S E GQDYEHV ML+++F++F+RDT IG ERV +AN
Sbjct: 1699 LRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFREFSRDTSTIGQERVDSANALA 1758
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIM 5436
+ LI GH T+A WKDSLNEAW +LLEL+DTR Q+L A+ L +F H R L+R+
Sbjct: 1759 NGLIAGGHAAWATVAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALARVQ 1818
Query: 5437 EKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDI 5616
K +PD GRD ++ AL R+H Y DI A+ QV Q++ D L+ YAGDKA +I
Sbjct: 1819 HKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEI 1878
Query: 5617 GSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKD 5796
G V +AW L+G AR L+DT+D F+F VR+L+LWMD + +M++QERP+D
Sbjct: 1879 GRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRD 1938
Query: 5797 VSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEM 5976
VS +L++ N Q +KAEI+AR + F+ACI +G++LL R HYA+ EI +KL +L + R E
Sbjct: 1939 VSSADLVIKNQQGIKAEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQET 1998
Query: 5977 MRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+W+++ ++LQL+LEV F RDA +AE+WL +QEP + S E G ++E LIK+HEAF
Sbjct: 1999 AEKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAF 2058
Query: 6157 EKSAFAQEERFLALEKLTTFELKET-QHREEETAKRRGPAHIGSPSRSTPAAETSFGAQD 6333
+KSA A EERF ALEKLT E +E Q R+ E +RR P S P A G+
Sbjct: 2059 QKSAVAWEERFSALEKLTALEERENEQKRKREEEERR-----KQPPTSEPMASQPEGSLV 2113
Query: 6334 DGAK-QGEAFEGT 6369
DG + A++GT
Sbjct: 2114 DGQRVLDTAWDGT 2126
Score = 316 bits (810), Expect = 4e-84
Identities = 408/1908 (21%), Positives = 753/1908 (39%), Gaps = 57/1908 (2%)
Frame = +1
Query: 1129 DINRAWQSLEK--AEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQD 1302
++ R W L + A L+L EL Q+ + L + AEM+ RL SQD
Sbjct: 508 NVARLWDFLREMVAARRERLLLNLEL--QKVFQDLLYLMDWMAEMKG-------RLQSQD 558
Query: 1303 NFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK---------I 1455
G L+ VE + HE +E DI ER + D K +
Sbjct: 559 -LGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASAL-----RFCDPGKEYRPCGPQLV 612
Query: 1456 NERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAH 1635
+ER + RR RLE S + + + L S + G
Sbjct: 613 SERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLLASAETGRD 672
Query: 1636 LMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDV 1815
L V LL KH L +++ + ++ Q Q+ P + R+
Sbjct: 673 LTGVLRLLNKHTALRGEMSGRLGPLKLTLEQGQQLVAEGHPGAN--------QASTRAAE 724
Query: 1816 LQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSH 1995
LQ +++ L LA ER +RL L QF D ++E + + +++SS + G D +
Sbjct: 725 LQAQWERLEALAEERAQRLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQA 784
Query: 1996 LLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSAS 2175
L +H+ E +R LD L L ++ + + R+ + + +L+ +
Sbjct: 785 LARQHRALEEEIRAHRPTLDALREQAAALPP-ALSHTPEVQGRVPTLEQHYEELQARAGE 843
Query: 2176 RKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQN 2355
R L + +Y ++A ++ + + ++ + + +++ ++ + + E+
Sbjct: 844 RARALEAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDPEVVQQRFETLEPEMNA 903
Query: 2356 FDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQK-AELENLSQLRKQRLIDALSLYKL 2532
I + AE L + + D L Q+ + +L+ +K L ALS+
Sbjct: 904 LAARITAVSDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLAGGKKAALTSALSIQNY 963
Query: 2533 YSDADSVESWIDEKGKLL-ATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLAR 2709
+ + ++W+ EK K++ +T G D+ V ++ + E+D++ A+V + A
Sbjct: 964 HLECTETQAWMREKTKVIESTQDLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEAN 1023
Query: 2710 QLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIED 2889
L + I R ++ W LR + ++ L A RL+ F + W+
Sbjct: 1024 ALAAGHPAQAPAINTRLGEVQTGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWL-G 1082
Query: 2890 KTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQ-EAQA 3066
+T+ S+ L L + + + ++ Q++ L +++ R++ +
Sbjct: 1083 RTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLF 1142
Query: 3067 IREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQ 3246
+R+ ++ + W+ L + + +L +A Q FLRD + L++ + ++ E P
Sbjct: 1143 LRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPG 1202
Query: 3247 SLAEA-------EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLA 3405
+L A E ++ A E I G E +++ + G+ + ++ + + +R
Sbjct: 1203 TLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGN-IHAEKIQEKADSIEKRHR 1261
Query: 3406 GLQEGWEELQ-RMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQA 3582
QE ++L R+ DNR+ Q FL+D ++ ++ + E L D+ S ++A
Sbjct: 1262 KNQEAVQQLLGRLRDNREQ--------QHFLQDCQELKLWID--EKMLTAQDV--SYDEA 1309
Query: 3583 EN---QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANR 3753
N + ++HQ F+ + AN + + V G +L + + +K ++ R
Sbjct: 1310 RNLHTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVLVSEKLEDLHRRWDELE 1369
Query: 3754 EKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQ 3930
Q + L DA + F C L W+E + + Y +D ++ + Q +
Sbjct: 1370 TTTQAKARSLFDANRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLE 1429
Query: 3931 SELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDAN 4110
E+A ++ ++ ++ A L + + G ++ + ++ L + +++ ++L +
Sbjct: 1430 REMAVREKEVEAIQAQAKALAQED-QSAGEVERTSRAVEEKFRALCQPMKDRCRRLQASR 1488
Query: 4111 RQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHI-DXX 4287
Q + + + D W T+ + + DL +V + M+K ++ E+ I D
Sbjct: 1489 EQHQFHRDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLK 1548
Query: 4288 XXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEK 4467
EL + QE +RL L+ R K LE A QF RD + +
Sbjct: 1549 ERQRTLRTAAAGPELAEL-------QEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAE 1601
Query: 4468 LWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHAN 4647
W+ E+ + Q + K Q+L + ++ I Q+ + Q++ID H
Sbjct: 1602 AWMGEQELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPE 1661
Query: 4648 GPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDE 4827
+ ++ + LKE +R+ L E + Q + + E W+ E+E+ E
Sbjct: 1662 STRLTIRQAQVDKLYAGLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHE 1721
Query: 4828 RGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQI----QVRQAQ 4995
G+D +E + DKF + R +T + V+ + L + A
Sbjct: 1722 LGQD----------YEHVTMLRDKFREFSRDTSTIGQERVDSANALANGLIAGGHAAWAT 1771
Query: 4996 I----EKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQE----NG 5151
+ + L D Y L R + Q +A V Q+ G
Sbjct: 1772 VAEWKDSLNEAWADLLELLDTRGQVLAAAYELQRFLHGARQALA--RVQHKQQQLPDGTG 1829
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
+D + LQ R + D + + ++ +DG + A I ++ EAW
Sbjct: 1830 RDLNAAEALQRRHCAYEHDIQALSTQVQQVQDDGLRLQKAYAGDKAEEIGRHMQAVAEAW 1889
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD--DLGRDSSSVGALSRK 5505
L R Q+L + +F+ R+ L M+ + D + RD SS + +
Sbjct: 1890 AQLQGSSAARRQLLLDTTDKFRFFKAVRE-LMLWMDGINLQMDAQERPRDVSSADLVIKN 1948
Query: 5506 HQNYLKDIAAIGEQVAQIERDAAEL--RDGYAGD----KALDIGSRESEVVKAWRHLRGL 5667
Q +I A ++ + EL R+ YA + K + SR E + W+
Sbjct: 1949 QQGIKAEIEARADRFSACIDMGQELLARNHYAAEEISEKLSQLQSRRQETAEKWQE---- 2004
Query: 5668 CDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAE 5847
+ L ++ F W+ + + S E V VE L+ H++ +
Sbjct: 2005 ---KMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKS 2061
Query: 5848 IDAREENFNACISLG--RDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLIL 6021
A EE F+A L + N + E E++ T+E M + E Q +L
Sbjct: 2062 AVAWEERFSALEKLTALEERENEQKRKREEEERRKQPPTSE--PMASQPEGSLVDGQRVL 2119
Query: 6022 EVYQFARDAAVAESWLFAQEPYL----ISKEYGRNLEETIKLIKKHEAFEKSAFAQEERF 6189
+ A D ++ Q P + E + L E +L + + + +E
Sbjct: 2120 DT---AWDGTQSKLPPSTQAPSINGVCTDTESSQPLLEQQRLEQSNVPEGPGSGTGDE-- 2174
Query: 6190 LALEKLTTFELKETQHREEETAKRRGPAHIGSP-SRSTPAAETS-FGAQDDGAKQGEAFE 6363
+ R E RGPA P SRS+ +A + A+ E E
Sbjct: 2175 ------------SSGPRGERQTLPRGPAPSPMPQSRSSESAHVATLPARGAELSAQEQME 2222
Query: 6364 GTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCS 6537
GTL RK E+ ++KAANRSW+ +Y VLR+ L FYKD + V HGE P++L
Sbjct: 2223 GTLCRKQEMEAFNKKAANRSWQNVYCVLRRGSLGFYKDARAASAGVPYHGEVPVSLARAQ 2282
Query: 6538 VNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQA 6681
+VA DY+K+K+V L L G EYLFQ E +M WL + A A
Sbjct: 2283 GSVAFDYRKRKHVFKLGLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 2330
>gi|38084794|ref|XP_129130.3| spectrin beta 3 [Mus musculus]
Length = 2409
Score = 1899 bits (4919), Expect = 0.0
Identities = 1003/2136 (46%), Positives = 1380/2136 (63%), Gaps = 26/2136 (1%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALA---------------------DERELVQKKTFTKWVN 153
D D+D D+SSARLFERSRIKALA DERE VQKKTFTKWVN
Sbjct: 30 DSDWDNDSSSARLFERSRIKALAAAFINPAQYASVLEGRFKQLQDEREAVQKKTFTKWVN 89
Query: 154 SHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRN 333
SHL RV+C+V DLY D+RDG+ LLRLL VLSGE LPKPT G+MRIHCLENV+K LQFL+
Sbjct: 90 SHLARVTCRVGDLYSDLRDGRNLLRLLEVLSGETLPKPTKGRMRIHCLENVDKALQFLKE 149
Query: 334 QHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQM 513
Q VHLEN+GSHDIVDGN RLTLGL+WTIILRFQIQDI+ E DN E +SAK+ALLLWCQM
Sbjct: 150 QKVHLENMGSHDIVDGNHRLTLGLVWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQM 209
Query: 514 KTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQL 693
KTAGYPNVNV NF+TSWRDGLAFNA++HKHRPDL+D+++L+K NA YNLQ+AF+ AE +L
Sbjct: 210 KTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQNAFNLAEKEL 269
Query: 694 GLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMIN 873
GL K LD EDVNVDQPDEKSIITYV TYYHYF+K+K ++GKRIGKV++ ME + ++
Sbjct: 270 GLTKLLDPEDVNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIGKVLDHAMEAEHLVE 329
Query: 874 RYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVL 1053
+YE+L+S+LL+WI I LN+R N+L GVQ QL FN YRT EKPPKF EKG LEVL
Sbjct: 330 KYESLASELLQWIEQTIVTLNDRQLANSLSGVQNQLQSFNSYRTVEKPPKFTEKGNLEVL 389
Query: 1054 LFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAA 1233
LFT+QS +RANNQ+ + PREG+LI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLAA
Sbjct: 390 LFTIQSKLRANNQKVYTPREGRLISDINKAWERLEKAEHERELALRTELIRQEKLEQLAA 449
Query: 1234 RFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXX 1413
RF+RKA MRETWL+ENQRLVSQDNFG +L++VEAA +KHEAIETDI AY R
Sbjct: 450 RFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVAYSGRVQAVDAVA 509
Query: 1414 XXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXX 1593
+YHD +I R+ NV ARR RL L++ +QK+F
Sbjct: 510 AELAAEHYHDIKRIAARQNNVARLWDFLRQMVAARRERLLLNLELQKVFQDLLYLMDWMA 569
Query: 1594 XIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGY 1773
+K RL S+DLG HL VEDLLQ H L+E+DI + ERV A A RF +P G Y
Sbjct: 570 EMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALRFCDP----GKEY 625
Query: 1774 KPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVL 1953
+P +P + ER L++ Y+ L +LAA R+ RLE+++RL +F W+V E E ++EQ+ +L
Sbjct: 626 RPCDPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGEAEAWVREQQHLL 685
Query: 1954 SSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAE 2133
+S DTGRD+ V LL KH + L G++L E PG++ R AE
Sbjct: 686 ASADTGRDLTGVLRLLNKHAALRGEMSGRLGPLKLTLEQGQQLVAEGHPGANQASTRAAE 745
Query: 2134 IRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQL 2313
++ +L+ L+ R ++LA YQF DA+D++ +L D LR++SS +VG DE + Q
Sbjct: 746 LQAQWERLEALAEERAQQLAQAASLYQFQADANDMEAWLVDALRLVSSPEVGHDEFSTQA 805
Query: 2314 LLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLR 2493
L ++H + +E++ + L +A +LP P+++ R+ T + EL+ + R
Sbjct: 806 LARQHRALEEEIRAHRPTLDALREQAAALPPALSHTPEVQGRVPTLEQHYEELQARAGER 865
Query: 2494 KQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQ 2673
+ L AL+ Y + S+A + W++EK + L L +E++E+++ RF+TLE +M
Sbjct: 866 ARALEAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNAL 925
Query: 2674 EAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFR 2853
A+VT VND+A QLL P D I+ Q +LN RW Q R + D K+ L A ++ +
Sbjct: 926 AARVTAVNDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYH 985
Query: 2854 IDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADD 3033
++C ET W+ +KT+V+E + L NDL+GV+ LQR+L+ ERDL AI A++ L +EA+
Sbjct: 986 LECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANA 1045
Query: 3034 IERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTAT 3213
+ P +A AI + + W+ L +R E L EA LQ FLR LD FQAWL T
Sbjct: 1046 LAAGHPAQAPAINTRLGEVQAGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRT 1105
Query: 3214 QRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLR 3393
Q VASEE P +L EAE LL QHAA+R E++ +Y ++R +G+ VT+DQ DPQ +FLR
Sbjct: 1106 QTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLR 1165
Query: 3394 QRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSL 3573
QRL L GWEEL RMW++RQ L+Q Q FLRDA+QAE +LS QE L+ ++P +L
Sbjct: 1166 QRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPGTL 1225
Query: 3574 EQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANR 3753
+ A+ +K+ +DF++TMDAN E+IR + G QL G+ A+KI +KA +I++R N+
Sbjct: 1226 QAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQ 1285
Query: 3754 EKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQS 3933
E Q++L +L+D Q FL DC ELR WI+EKM+ AQD +Y +A+ + +K+ +HQAF +
Sbjct: 1286 EAVQQLLGRLRDNREQQHFLQDCQELRLWIDEKMLTAQDVSYDEARNLHTKWQKHQAFMA 1345
Query: 3934 ELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANR 4113
ELAANK+ LD++ L +KPE + ++E+L +WDELE TT+ K + LFDANR
Sbjct: 1346 ELAANKDWLDKVDKEGRELTLEKPELKVVVSEKLEDLHRRWDELETTTQAKARSLFDANR 1405
Query: 4114 QQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXX 4293
+L+ QS + ++ W L+ ++ +D DLT+VN+ ++KQ ++E EM + + ++
Sbjct: 1406 AELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAVREKEVEAIQA 1465
Query: 4294 XXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLW 4473
E + R AV+E+ + L P+ +R + L + QF RDV+DE LW
Sbjct: 1466 QAQALAQEDQSAGEVERTSR-AVEEKFRALCQPMKERCRRLHASREQHQFHRDVEDEILW 1524
Query: 4474 ISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGP 4653
++ERL +A + G+ LP L K Q L EI HEP I + + L A GP
Sbjct: 1525 VTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLKERQRTL--GTAAAGP 1582
Query: 4654 AFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERG 4833
++ EL+ W+ L ++ R L E+ +A QF D EAEAWM EQEL+MM E+
Sbjct: 1583 ----ELAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMGEQELHMMGQEKA 1638
Query: 4834 KDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYA 5013
KDE S + ++KKH+ L+ + +A TI+ LA + ++ + P + ++ +RQAQ++KLYA
Sbjct: 1639 KDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLTIRQAQVDKLYA 1698
Query: 5014 GLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQ 5193
L++ L RE+DDL QWI ++EVVA S E GQDYEHV ML+++F+
Sbjct: 1699 SLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVTMLRDKFR 1758
Query: 5194 QFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQIL 5373
+F++DT IG ERV +AN + LI GH T+A WKDSLNEAW +LLEL+DTR Q+L
Sbjct: 1759 EFSKDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLELLDTRGQVL 1818
Query: 5374 EASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVA 5553
A+ L +F H R L+R+ K +PD GRD ++ AL R+H Y DI A+ QV
Sbjct: 1819 AAAYELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAYEHDIQALSTQVQ 1878
Query: 5554 QIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVR 5733
Q++ D L+ YAGDKA +IG V +AW L+G AR L+DT+D F+F VR
Sbjct: 1879 QVQDDGQRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLDTTDKFRFFKAVR 1938
Query: 5734 DLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRK 5913
+L+LWMD + +M++QERP+DVS +L++ N Q +KAEI+AR + F++CI +G++LL R
Sbjct: 1939 ELMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSSCIDMGQELLARS 1998
Query: 5914 HYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLI 6093
HYA+ EI +KL +L + R E +W+++ ++LQL+LEV F RDA +AE+WL +QEP +
Sbjct: 1999 HYAAEEISEKLSQLQSRRQETADKWQEKMDWLQLVLEVLVFGRDAGMAEAWLCSQEPLVR 2058
Query: 6094 SKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQH---REEETAKRR 6264
S E G ++E LIK+HEAF+KSA A EERF ALEKLT E +E + REEE +++
Sbjct: 2059 SAELGCTVDEVESLIKRHEAFQKSAVAWEERFSALEKLTALEERENERKRKREEEERRKQ 2118
Query: 6265 GPAHIGSPSRSTPAAETSFGAQDDGAKQGE-AFEGT 6369
P S P A G+ DG + + A++GT
Sbjct: 2119 -------PPTSEPMASQPEGSLVDGQRVPDTAWDGT 2147
Score = 100 bits (250), Expect = 4e-19
Identities = 62/152 (40%), Positives = 80/152 (51%), Gaps = 4/152 (2%)
Frame = +1
Query: 6238 REEETAKRRGPAHIGSP-SRSTPAAE-TSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKA 6411
R E RGPA P SRS+ AA + + E EG L RK E+ ++KA
Sbjct: 2200 RGERQTLPRGPAPSPMPQSRSSEAAHGATLPTRGPELSAQEQMEGMLCRKQEMEAFNKKA 2259
Query: 6412 ANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSL 6585
ANRSW+ +Y VLR+ L FYKD + V HGE P++L +VA DY+K+K+V L
Sbjct: 2260 ANRSWQNVYCVLRRGSLGFYKDARAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKL 2319
Query: 6586 RLPIGAEYLFQCGSEEDMQRWLTELQVATGQA 6681
L G EYLFQ E +M WL + A A
Sbjct: 2320 GLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 2351
>gi|27413156|ref|NP_000338.2| spectrin, beta, erythrocytic (includes
spherocytosis, clinical type I); Spectrin, beta,
erythrocytic; spectrin, beta, erythrocytic (includes
sperocytosis, clinical type I) [Homo sapiens]
gi|338441|gb|AAA60579.1| beta-spectrin
Length = 2137
Score = 1886 bits (4885), Expect = 0.0
Identities = 974/2102 (46%), Positives = 1373/2102 (64%), Gaps = 12/2102 (0%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +DNSSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LPKPT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + ETRSAK+ALLLWCQMKTAGYP+VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AF+ AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+A + REL L+ ELIRQEKLEQLA RF+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAGYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLNENQRLVAQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I RK+N+
Sbjct: 448 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVRALEDLAQELEKENYHDQKRITARKDNIL 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ LLS + G HL++VEDLL
Sbjct: 508 RLWSYLQELLQSRRQRLETTLALQKLFQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ ++EL
Sbjct: 568 QKHKLMEADIAIQGDKVKAITAATLKF-----TEGKGYQPCDPQVIQDRMSHLEQCFEEL 622
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA + +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 623 SNMAAGARTQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 682
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L+++ + G I R+ E+ ++LK+L+A K+ L
Sbjct: 683 EDELRGLDAHLEQIFQEAHGMVARKQFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDA 742
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH D +EL+ ++ L
Sbjct: 743 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHL 802
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL + ++ + LR+QRL +AL LY ++ + D+ E
Sbjct: 803 EQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACEL 862
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EK K LA + +E++E+++HRFD L+Q+MK ++ VN A L+ HP S
Sbjct: 863 WMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRS 922
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q+ LN RW + +V ++R ++ A R+ T +DC+ET WI DKT+V+E +
Sbjct: 923 REVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHTLCVDCEETSKWITDKTKVVESTKD 982
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L DL+G++ +QR+LS +ERD+ AIQA++D+L +E+ + P++ + I + K + ++
Sbjct: 983 LGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQLMDSHPEQKENIGQRQKHLEEL 1042
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L + ++ E L E LQ FL+DLD FQAWL+ TQ+ VASE+ P+SL EAEQLL Q
Sbjct: 1043 WQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQ 1102
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HA I++EIDG+ + Y++++ G++V Q QTDP+Y+ L QRL GL GW+ L RMW++R H
Sbjct: 1103 HAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWDALGRMWESRSH 1162
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SLE AE +++ +DF+ +M+ N +
Sbjct: 1163 TLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRD 1222
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K+ + G++L +G+ +DKI +K + I++R N EKAQE L+D L LQ FL +
Sbjct: 1223 KVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQN 1282
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ +QD +Y +A+ + +K+++HQAF +ELA+++ L+ + L D+
Sbjct: 1283 CQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDE 1342
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L WDEL+ TT+EK Q L A L +Q+ AD+ +W + +E+++
Sbjct: 1343 KPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQL 1402
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLT+VN + K +E ++ + + + P E L+
Sbjct: 1403 RSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQV-------PSMGEEGGDADLS 1455
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE +A Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1456 IEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1515
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + GQ+L++ + E+++ L+S+W L+EA
Sbjct: 1516 FMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAG 1575
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L ++ +A Q+ D EAEAW+ EQELY++ DE KDE +K+H R Q ++
Sbjct: 1576 RLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVED 1635
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA++A + P EQI Q Q++K YAGL+D + L
Sbjct: 1636 YGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQL 1695
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI++KE+VA S E GQD++HV +L+++F+ FAR+T IG ERV N N +
Sbjct: 1696 KRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIE 1755
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LNE W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1756 RLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDE 1815
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +D+ +G QV Q + A L+ YAG+KA I
Sbjct: 1816 KHRELPEDVGLDASTAESFHRVHTAFERDVHLLGVQVQQFQDVATRLQTAYAGEKAEAIQ 1875
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
++E EV AW+ L C R ++L+DT+D F+F +M RDLL WM+ + R++ +QERP+DV
Sbjct: 1876 NKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDV 1935
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELLM HQ + AEI+ R +NF+AC+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1936 SSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMN 1995
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE RWE L+++LEV QF+RDA+VAE+WL AQEPYL S ++G ++ KLIK+HEAFE
Sbjct: 1996 EKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFE 2055
Query: 6160 KSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTP 6303
KS + ERF ALEK TT ELKE Q E ETA +H + R++P
Sbjct: 2056 KSTASWAERFAALEKPTTLELKERQIAERPAEETGPQEEEGETAGEAPVSHHAATERTSP 2115
Query: 6304 AA 6309
+
Sbjct: 2116 VS 2117
>gi|134798|sp|P11277|SPCB_HUMAN Spectrin beta chain, erythrocyte
(Beta-I spectrin)
gi|71568|pir||SJHUB spectrin beta chain - human
Length = 2137
Score = 1882 bits (4874), Expect = 0.0
Identities = 972/2102 (46%), Positives = 1373/2102 (65%), Gaps = 12/2102 (0%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +DNSSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LPKPT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + ETRSAK+ALLLWCQMKTAGYP+VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AF+ AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+A + REL L+ ELIRQEKLEQLA RF+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAGYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLNENQRLVAQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I RK+N+
Sbjct: 448 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVRALEDLAQELEKENYHDQKRITARKDNIL 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ LLS + G HL++VEDLL
Sbjct: 508 RLWSYLQELLQSRRQRLETTLALQKLFQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ ++EL
Sbjct: 568 QKHKLMEADIAIQGDKVKAITAATLKF-----TEGKGYQPCDPQVIQDRMSHLEQCFEEL 622
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA + +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 623 SNMAAGARTQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 682
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L+++ + + G I R+ E+ ++LK+L+A K+ L
Sbjct: 683 EDELRGLDAHLEQIFQEAHGMVARNEFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDA 742
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH D +EL+ ++ L
Sbjct: 743 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHL 802
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL + ++ + LR+QRL +AL LY ++ + D+ E
Sbjct: 803 EQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACEL 862
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EK K LA + +E++E+++HRFD L+Q+MK ++ VN A L+ HP S
Sbjct: 863 WMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRS 922
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q+ LN RW + +V ++R ++ A R+ T +DC+ET WI DKT+V+E +
Sbjct: 923 REVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHTLCVDCEETSKWITDKTKVVESTKD 982
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
DL+G++ +QR+LS +ERD+ AIQA++D+L +E+ + P++ + I + K + ++
Sbjct: 983 PGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQLMDSHPEQKENIGQRQKHLEEL 1042
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L + ++ E L E LQ FL+DLD FQAWL+ TQ+ VASE+ P+SL EAEQLL Q
Sbjct: 1043 WQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQ 1102
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HA I++EIDG+ + Y++++ G++V Q QTDP+Y+ L QRL GL GW+ L RMW++R H
Sbjct: 1103 HAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWDALGRMWESRSH 1162
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SLE AE +++ +DF+ +M+ N +
Sbjct: 1163 TLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRD 1222
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K+ + G++L +G+ +DKI +K + I++R N EKAQE L+D L LQ FL +
Sbjct: 1223 KVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQN 1282
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ +QD +Y +A+ + +K+++HQAF +ELA+++ L+ + L D+
Sbjct: 1283 CQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDE 1342
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L WDEL+ TT+EK Q L A L +Q+ AD+ +W + +E+++
Sbjct: 1343 KPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQL 1402
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLT+VN + K +E ++ + + + P E L+
Sbjct: 1403 RSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQV-------PSMGEEGGDADLS 1455
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE +A Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1456 IEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1515
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + GQ+L++ + E+++ L+S+W L+EA
Sbjct: 1516 FMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAG 1575
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L ++ +A Q+ D EAEAW+ EQELY++ DE KDE +K+H R Q ++
Sbjct: 1576 RLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVED 1635
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA++A + P EQI Q Q++K YAGL+D + L
Sbjct: 1636 YGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQL 1695
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI++KE+VA S E GQD++HV +L+++F+ FAR+T IG ERV N N +
Sbjct: 1696 KRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIE 1755
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LNE W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1756 RLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDE 1815
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +++ +G QV Q + A L+ YAG+KA I
Sbjct: 1816 KHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKAEAIQ 1875
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
++E EV AW+ L C R ++L+DT+D F+F +M RDLL WM+ + R++ +QERP+DV
Sbjct: 1876 NKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDV 1935
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELLM HQ + AEI+ R +NF+AC+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1936 SSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMN 1995
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE RWE L+++LEV QF+RDA+VAE+WL AQEPYL S ++G ++ KLIK+HEAFE
Sbjct: 1996 EKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFE 2055
Query: 6160 KSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTP 6303
KS + ERF ALEK TT ELKE Q E ETA +H + R++P
Sbjct: 2056 KSTASWAERFAALEKPTTLELKERQIAERPAEETGPQEEEGETAGEAPVSHHAATERTSP 2115
Query: 6304 AA 6309
+
Sbjct: 2116 VS 2117
>gi|338440|gb|AAA60578.1| spectrin Rouen (beta-220-218) mutant coding
sequence
Length = 2106
Score = 1874 bits (4854), Expect = 0.0
Identities = 962/2058 (46%), Positives = 1356/2058 (65%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +DNSSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRITDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LPKPT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPKPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + ETRSAK+ALLLWCQMKTAGYP+VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AF+ AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFNVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTITVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLTGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+A + REL L+ ELIRQEKLEQLA RF+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAGYRRELALRNELIRQEKLEQLARRFDRKAAMRETWLNENQRLVAQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I RK+N+
Sbjct: 448 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVRALEDLAQELEKENYHDQKRITARKDNIL 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ LLS + G HL++VEDLL
Sbjct: 508 RLWSYLQELLQSRRQRLETTLALQKLFQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ ++EL
Sbjct: 568 QKHKLMEADIAIQGDKVKAITAATLKF-----TEGKGYQPCDPQVIQDRMSHLEQCFEEL 622
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA + +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 623 SNMAAGARTQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 682
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L+++ + G I R+ E+ ++LK+L+A K+ L
Sbjct: 683 EDELRGLDAHLEQIFQEAHGMVARKQFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDA 742
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH D +EL+ ++ L
Sbjct: 743 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHL 802
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL + ++ + LR+QRL +AL LY ++ + D+ E
Sbjct: 803 EQQAQGFPEEFRDSPDVTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACEL 862
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EK K LA + +E++E+++HRFD L+Q+MK ++ VN A L+ HP S
Sbjct: 863 WMGEKEKWLAEMEMPDTLEDLEVVQHRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRS 922
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q+ LN RW + +V ++R ++ A R+ T +DC+ET WI DKT+V+E +
Sbjct: 923 REVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHTLCVDCEETSKWITDKTKVVESTKD 982
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L DL+G++ +QR+LS +ERD+ AIQA++D+L +E+ + P++ + I + K + ++
Sbjct: 983 LGRDLAGIIAIQRKLSGLERDVAAIQARVDALERESQQLMDSHPEQKENIGQRQKHLEEL 1042
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L + ++ E L E LQ FL+DLD FQAWL+ TQ+ VASE+ P+SL EAEQLL Q
Sbjct: 1043 WQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQ 1102
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HA I++EIDG+ + Y++++ G++V Q QTDP+Y+ L QRL GL GW+ L RMW++R H
Sbjct: 1103 HAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWDALGRMWESRSH 1162
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SLE AE +++ +DF+ +M+ N +
Sbjct: 1163 TLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRD 1222
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K+ + G++L +G+ +DKI +K + I++R N EKAQE L+D L LQ FL +
Sbjct: 1223 KVLSPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQN 1282
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ +QD +Y +A+ + +K+++HQAF +ELA+++ L+ + L D+
Sbjct: 1283 CQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDE 1342
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L WDEL+ TT+EK Q L A L +Q+ AD+ +W + +E+++
Sbjct: 1343 KPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQL 1402
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLT+VN + K +E ++ + + + P E L+
Sbjct: 1403 RSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQV-------PSMGEEGGDADLS 1455
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE +A Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1456 IEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1515
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + GQ+L++ + E+++ L+S+W L+EA
Sbjct: 1516 FMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAG 1575
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L ++ +A Q+ D EAEAW+ EQELY++ DE KDE +K+H R Q ++
Sbjct: 1576 RLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVED 1635
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA++A + P EQI Q Q++K YAGL+D + L
Sbjct: 1636 YGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQL 1695
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI++KE+VA S E GQD++HV +L+++F+ FAR+T IG ERV N N +
Sbjct: 1696 KRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIE 1755
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LNE W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1756 RLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDE 1815
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +D+ +G QV Q + A L+ YAG+KA I
Sbjct: 1816 KHRELPEDVGLDASTAESFHRVHTAFERDVHLLGVQVQQFQDVATRLQTAYAGEKAEAIQ 1875
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
++E EV AW+ L C R ++L+DT+D F+F +M RDLL WM+ + R++ +QERP+DV
Sbjct: 1876 NKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDV 1935
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELLM HQ + AEI+ R +NF+AC+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1936 SSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMN 1995
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE RWE L+++LEV QF+RDA+VAE+WL AQEPYL S ++G ++ KLIK+HEAFE
Sbjct: 1996 EKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFE 2055
Query: 6160 KSAFAQEERFLALEKLTT 6213
KS + ERF ALEK TT
Sbjct: 2056 KSTASWAERFAALEKPTT 2073
Score = 231 bits (588), Expect = 2e-58
Identities = 290/1498 (19%), Positives = 594/1498 (39%), Gaps = 46/1498 (3%)
Frame = +1
Query: 1234 RFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXX 1413
+F + + E+W+ E +++ S ++G DL+SV +KH+A E ++ +
Sbjct: 641 KFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLEQIFQEA 700
Query: 1414 XXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXX 1593
+I R + V + L+ + + F
Sbjct: 701 HGMVARKQFGHPQIEARIKEVSAQWDQLKDLAAFCKKNLQDA---ENFFQFQGDADDLKA 757
Query: 1594 XIKS--RLLS-EDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNP--DGP 1758
++ RLLS ED+G L +KH ++ + + QAQ F D P
Sbjct: 758 WLQDAHRLLSGEDVGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSP 817
Query: 1759 DGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKE 1938
D + R L++ Y++++ A R++RL++ L + + E + E
Sbjct: 818 D-----------VTHRLQALRELYQQVVAQADLRQQRLQEALDLYTVFGETDACELWMGE 866
Query: 1939 QEQVLSST---DTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSD 2109
+E+ L+ DT D+ V H + + ++ L +D ++++ L + P S
Sbjct: 867 KEKWLAEMEMPDTLEDLEVVQH---RFDILDQEMKTLMTQIDGVNLAANSLVESGHPRSR 923
Query: 2110 NIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVM-SSEDV 2286
+ + + L + R+E + + + D ++ +++ D +V+ S++D+
Sbjct: 924 EVKQYQDHLNTRWQAFQTLVSERREAVDSALRVHTLCVDCEETSKWITDKTKVVESTKDL 983
Query: 2287 GKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEARE----HPDIRQRLDTTL 2454
G+D + + +K L ++ + + A+ ++L +E+++ HP+ ++ +
Sbjct: 984 GRDLAGIIAIQRK-------LSGLERDVAAIQARVDALERESQQLMDSHPEQKENIGQRQ 1036
Query: 2455 KQKAEL----ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEV 2622
K EL + Q ++ L + L D D ++W+ K +A+ + E
Sbjct: 1037 KHLEELWQGLQQSLQGQEDLLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEA 1096
Query: 2623 EIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDIL-HRQNKLNARWAQLRDM 2799
E + + ++ ++ + V + +++ + +L R L+ W L M
Sbjct: 1097 EQLLQQHAGIKDEIDGHQDSYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWDALGRM 1156
Query: 2800 VDQKRNELERAHRLETFRIDCQETVTWIEDKTRVL---EDSDALTNDLSGVMKLQRRLSM 2970
+ + + L + + F+ D ++ + ++ L E D+L +G+ K + L
Sbjct: 1157 WESRSHTLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGS 1216
Query: 2971 MERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDE 3150
ME + + + +DS +K + E + I+E ++ I N+K +E L +
Sbjct: 1217 MENNRDKVLSPVDSGNK----LVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRD 1272
Query: 3151 AGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ---HAAIREEIDGYAED 3321
+LQ FL++ W+ + + S++ S EA L N+ H A E+ +
Sbjct: 1273 NLELQNFLQNCQELTLWIN--DKLLTSQDV--SYDEARNLHNKWLKHQAFVAELASHEGW 1328
Query: 3322 YKKMRAMGDRVTQDQTDPQYMFL-RQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLR 3498
+ + A G ++ ++ PQ+ L Q+L L W+ELQ + LS + + L+
Sbjct: 1329 LENIDAEGKQLMDEK--PQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQ 1386
Query: 3499 DAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLC 3678
+S E+ L DD + L L + + ++ E++ + +
Sbjct: 1387 THADLNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMG 1446
Query: 3679 QDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMI 3858
++G A I K+ ++ E G +++ + KL Q D ++ W+EE++
Sbjct: 1447 EEGGDADLSIEKRFLDLLEPLGRRKKQLESSRAKL-------QISRDLEDETLWVEERLP 1499
Query: 3859 RAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQI 4035
AQ Y + +T+ ++Q Q+E+ + R++ + L + ++ ++
Sbjct: 1500 LAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERL 1559
Query: 4036 EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTV 4215
L + WD L + + Q+L DAN Q Y + + W + E + ++ P D
Sbjct: 1560 GHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGA 1619
Query: 4216 NVAMQKQHLIETEMIKK-AQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAP 4392
+ M K+HL + ++ ++I E E I + V + L+
Sbjct: 1620 -IVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDV 1678
Query: 4393 LDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNE 4572
++R++ LE FQ R+ DD + WISE+ ++A + +G+ L+ + + E
Sbjct: 1679 AEERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARE 1738
Query: 4573 --------IDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKG 4728
+DN +I + LID GH+ + L W +L E + R
Sbjct: 1739 TGAIGQERVDNVNAFI-------ERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQ 1791
Query: 4729 DLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDI----- 4893
L S H++ Y E + E+ + +D G D + ++ + H + D+
Sbjct: 1792 LLAASYDLHRYFYTGAEILGLIDEKHRELPEDV-GLDASTAESFHRVHTAFERDVHLLGV 1850
Query: 4894 --DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXX 5067
+F D L T + EK+ E IQ ++ ++ + L D
Sbjct: 1851 QVQQFQDVATRLQTA---YAGEKA---EAIQNKEQEVSAAWQALLDACAGRRTQLVDTAD 1904
Query: 5068 XYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAN 5247
+ DLL W+ +QE +D V++L + Q + E A
Sbjct: 1905 KFRFFSMARDLLSWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLE 1964
Query: 5248 DGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLS 5427
G ++L+ H + I ++ L + E+ + E R+L + RD
Sbjct: 1965 LG-ESLLQRQHQASEEI---REKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASV 2020
Query: 5428 R----IMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDG 5589
I ++ + D G SV L ++H+ + K A+ E+ A +E+ R G
Sbjct: 2021 AEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALEKPTTASRGG 2078
Score = 145 bits (366), Expect = 1e-32
Identities = 130/629 (20%), Positives = 260/629 (40%), Gaps = 8/629 (1%)
Frame = +1
Query: 4402 RRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDN 4581
R++ LE+ A +F R + W++E L N G L +K + + +
Sbjct: 416 RQEKLEQ--LARRFDRKAAMRETWLNENQRLVAQDNFGYDLAAVEAAKKKHEAIETDTAA 473
Query: 4582 HEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQF 4761
+E + + + QEL E + + + + W L+E ++ R+ L + +
Sbjct: 474 YEERVRALEDLAQELEKENYHDQKRITARKDNILRLWSYLQELLQSRRQRLETTLALQKL 533
Query: 4762 LYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHK 4941
D + WM E + +++ E GK ++ ++KH+ +++DI D ++A+ K
Sbjct: 534 FQDMLHSIDWMDEIKAHLLSAEFGKHLLEVEDLLQKHKLMEADIAIQGDKVKAITAATLK 593
Query: 4942 FVEEKS--PLTEQ-IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWI 5112
F E K P Q IQ R + +E+ + L + + E+D+ WI
Sbjct: 594 FTEGKGYQPCDPQVIQDRMSHLEQCFEELSNMAAGARTQLEQSKRLWKFFWEMDEAESWI 653
Query: 5113 ADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGS--ERVANANDGCDTLIGHGHTD 5286
+KE + S + G+D V +LQ + + F + + + E++ G GH
Sbjct: 654 KEKEQIYSSLDYGKDLTSVLILQRKHKAFEDELRGLDAHLEQIFQEAHGMVARKQFGH-- 711
Query: 5287 APTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM--PD 5460
P I ++ W+ L +L + L+ + +F D D L ++ H + +
Sbjct: 712 -PQIEARIKEVSAQWDQLKDLAAFCKKNLQDAENFFQFQGDADD-LKAWLQDAHRLLSGE 769
Query: 5461 DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVV 5640
D+G+D + AL +KH+++L+++ + +E+ A + + D+ R +
Sbjct: 770 DVGQDEGATRALGKKHKDFLEELEESRGVMEHLEQQAQGFPEEFRDSP--DVTHRLQALR 827
Query: 5641 KAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLM 5820
+ ++ + D R RL + DL+ LWM E ++ + E P + +E++
Sbjct: 828 ELYQQVVAQADLRQQRLQEALDLYTVFGETDACELWMGEKEKWLAEMEMPDTLEDLEVVQ 887
Query: 5821 NNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRW 6000
+ L E+ + L+ H S E+++ L T +R
Sbjct: 888 HRFDILDQEMKTLMTQIDGVNLAANSLVESGHPRSREVKQYQDHLNTRWQAFQTLVSERR 947
Query: 6001 EYLQLILEVYQFARDAAVAESWLFAQEPYLIS-KEYGRNLEETIKLIKKHEAFEKSAFAQ 6177
E + L V+ D W+ + + S K+ GR+L I + +K E+ A
Sbjct: 948 EAVDSALRVHTLCVDCEETSKWITDKTKVVESTKDLGRDLAGIIAIQRKLSGLERDVAAI 1007
Query: 6178 EERFLALEKLTTFELKETQHREEETAKRR 6264
+ R ALE+ + +L ++ ++E +R
Sbjct: 1008 QARVDALER-ESQQLMDSHPEQKENIGQR 1035
>gi|47058982|ref|NP_997687.1| erythroid spectrin beta [Rattus
norvegicus]
gi|33303720|gb|AAQ02379.1| erythroid spectrin beta [Rattus
norvegicus]
Length = 2137
Score = 1868 bits (4838), Expect = 0.0
Identities = 970/2102 (46%), Positives = 1368/2102 (64%), Gaps = 12/2102 (0%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +D+SSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDSSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LP+PT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + ETRSAK+ALLLWCQMKTAGYP VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPQVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AFD AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+AE++REL L+ ELIRQEKLEQLA RF+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAEYQRELALRSELIRQEKLEQLARRFDRKAAMRETWLNENQRLVTQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I+ RK N+
Sbjct: 448 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRISARKNNIL 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ +LS + G HL++VEDLL
Sbjct: 508 RLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ + EL
Sbjct: 568 QKHKLMEADIAIQGDKVKTITAATLQF-----TEGKGYQPCDPQVIQDRVSHLEQCFSEL 622
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA RK +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 623 SNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 682
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L ++ +++ + G I R+ E+ + LKEL+A RK+ L
Sbjct: 683 EDELRGLDAHLKQIFQEAEDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDA 742
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH + +EL+ ++ L
Sbjct: 743 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHL 802
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL K ++ ++LR +L +AL LY ++ ++D+ E
Sbjct: 803 ENQAQGFPEEFRDSPDVTNRLQALRKLYQQVMAQAELRGHKLQEALDLYTVFGESDACEL 862
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EKGK L + +E++E+++HRFD L+Q+MK A++ VN A L+ HP S
Sbjct: 863 WMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRS 922
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q++LN RW + +V ++R ++ A R+ + +DC+ET WI DKT+V+E +
Sbjct: 923 GEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIVDKTKVVESTKD 982
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L DL+GV+ +QR+LS +ERD+ AI+ ++ +L +E+ + P + + I + + ++
Sbjct: 983 LGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPDQKEDIGQRQADVEKM 1042
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L ++ E L EA LQ FL+DLD F+AWL+ Q+ VASE+ P+SL EAEQLL Q
Sbjct: 1043 WKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQ 1102
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HAAI+EEID + +DY +++A G++V + QTDP Y L QRL GL W+ L RMW++R +
Sbjct: 1103 HAAIKEEIDAHKDDYHRVKASGEKVIEGQTDPDYQLLGQRLEGLDTDWDALWRMWESRGN 1162
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SL AE +++ +DF+ +M+ N +
Sbjct: 1163 TLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRD 1222
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K+ + G+ L +G+ ++KI +K + I++R N EKAQEV LKD L LQ FL +
Sbjct: 1223 KVLSPVDSGNMLVSEGNLYSNKIKEKVQLIEDRHMKNNEKAQEVTALLKDNLELQNFLQN 1282
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ + D +Y +A+ + +K+++HQAF +ELA+++ L+ + L +
Sbjct: 1283 CKELTLWINDKLLTSPDISYDEARNLHNKWMKHQAFMAELASHQGWLENIVAEGRQLMAE 1342
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L WDEL+ TT+ K ++L A L +Q+ AD+ +W + +E+++
Sbjct: 1343 KPQFTDVVSERLEALHKLWDELQTTTKAKTEQLSAARSSDLRLQTHADLSKWISAMEDQL 1402
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLTTVN + K +E ++ + + ++ D ++
Sbjct: 1403 RSDDLGKDLTTVNRMLVKLKRVEEQVNLRKEELEELFAEAPPLGAEAGDT-------DMS 1455
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE KA Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1456 IEKRFLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1515
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + + GQEL+ + E+++ L+S+W L+EA
Sbjct: 1516 FMKKNQTLQNEILGHAPRVEDVLHRGQELVKAAEIDCQDIEERLGHLQSSWDTLREAAAG 1575
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L E+ +A Q+ D GEAEAW+SEQELY+ DE KDE +K+H R Q +++
Sbjct: 1576 RLQRLREAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEE 1635
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA +A + P EQI Q Q++K YAGL+D + L
Sbjct: 1636 YGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRKLENMYHLFQL 1695
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI +KE+VA SQE GQD++HV ML+++F+ FAR+T IG ERV N N +
Sbjct: 1696 KREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVNSIIE 1755
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LN+ W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1756 RLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDE 1815
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +++ +G QV Q + A L+ YAG+KA I
Sbjct: 1816 KHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQ 1875
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
S+E EV AW+ L C R ++L+DT+D F+F +MVRDLL WM+ + R++ +QERP+DV
Sbjct: 1876 SKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDV 1935
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELL+ HQ +KAEI+ R +NF+ C+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1936 SSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMN 1995
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE R + L ++LEV QF+RDA+VAE+WL AQEPYL S+++G ++ KLIK+HEAFE
Sbjct: 1996 DKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFE 2055
Query: 6160 KSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTP 6303
KS + ERF ALEK TT ELKE Q E ETA H + R++P
Sbjct: 2056 KSTASWAERFAALEKPTTLELKERQTPDRPTEEPGPQEEEGETAGEAPQVHHAATERTSP 2115
Query: 6304 AA 6309
+
Sbjct: 2116 VS 2117
>gi|50300486|ref|NP_038703.2| spectrin beta 1; beta-spectrin 1;
spectrin R; spectrin bata 1 [Mus musculus]
Length = 2137
Score = 1863 bits (4826), Expect = 0.0
Identities = 967/2102 (46%), Positives = 1366/2102 (64%), Gaps = 12/2102 (0%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +DNSSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LP+PT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + E RSAK+ALLLWCQMKTAGYP+VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGREQRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AFD AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+AE++REL L+ ELIRQEKLEQLA RF+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAEYQRELALRSELIRQEKLEQLARRFDRKAAMRETWLNENQRLVTQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I RK+N+
Sbjct: 448 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRIIARKDNIL 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ +LS + G HL++VEDLL
Sbjct: 508 RLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ + EL
Sbjct: 568 QKHKLMEADIAIQGDKVKAITAATLQF-----AEGKGYQPCDPQVIQDRVSHLEQCFSEL 622
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA RK +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 623 SNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 682
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L ++ ++ + G I R+ E+ + LKEL+A RK+ L
Sbjct: 683 EDELRGLDAHLKQIFQEADDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDA 742
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH + +EL+ ++ L
Sbjct: 743 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHL 802
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL K ++ ++LR +L +AL LY ++ ++D+ E
Sbjct: 803 EHQAQGFPEEFRDSPDVTNRLQALRKLYQQVLTQAELRGHKLQEALDLYTVFGESDACEL 862
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EKGK L + +E++E+++HRFD L+Q+MK A++ VN A L+ HP S
Sbjct: 863 WMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRS 922
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q++LN RW + +V ++R ++ A R+ + +DC+ET WI DKT+V+E +
Sbjct: 923 GEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIMDKTKVVESTKD 982
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L DL+GV+ +QR+LS +ERD+ AI+ ++ +L +E+ + P++ + I + + ++
Sbjct: 983 LGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPEQKEDIGQRQADVEKL 1042
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L ++ E L EA LQ FL+DLD F+AWL+ Q+ VASE+ P+SL EAEQLL Q
Sbjct: 1043 WKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQ 1102
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HAAI+EEID + +DY +++A G++V + QTDP Y L QRL GL W+ L+RMW++R +
Sbjct: 1103 HAAIKEEIDAHRDDYHRVKASGEKVIEGQTDPDYQLLGQRLEGLDTDWDALRRMWESRGN 1162
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SL AE +++ +DF+ +M+ N +
Sbjct: 1163 TLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRD 1222
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
KI + G++L +G+ ++KI +K + I++R N EKAQE LKD L LQ FL +
Sbjct: 1223 KILSPVDSGNKLVAEGNLYSNKIMEKVQLIEDRHKKNNEKAQEATVLLKDNLELQNFLQN 1282
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ + D +Y +A+ + +K+++HQAF +ELA+++ L+ + L +
Sbjct: 1283 CKELTLWINDKLLTSPDVSYDEARNLHNKWMKHQAFMAELASHQGWLENIDAEGRQLMAE 1342
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L W+EL+ T + K ++L A L +Q+ AD+ +W +E+++
Sbjct: 1343 KPQFKDVVSERLEALHKLWEELQSTAKAKAEQLSAARSSDLRLQTHADLNKWIGAMEDQL 1402
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLTTVN + K +E ++ + + ++ D ++
Sbjct: 1403 RSDDLGKDLTTVNRMLAKLKRVEEQVNLRKEELEELFADAPSLGAEAGDT-------DMS 1455
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE KA Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1456 IEKRFLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1515
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + GQEL+ + E+++ L+S+W L+EA
Sbjct: 1516 FMKKNQTLQNEILGHAPRVEDVLRRGQELVKAAEIDCQDIEERLGHLQSSWDTLREAAAG 1575
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L ++ +A Q+ D GEAEAW+SEQELY+ DE KDE +K+H R Q +++
Sbjct: 1576 RLQRLRDAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEE 1635
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA +A + P EQI Q Q++K YAGL+D + L
Sbjct: 1636 YGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRRLENMYHLFQL 1695
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI +KE+VA SQE GQD++HV ML+++F+ FAR+T IG ERV N N +
Sbjct: 1696 KREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVNTIIE 1755
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LN+ W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1756 RLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDE 1815
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +++ +G QV Q + A L+ YAG+KA I
Sbjct: 1816 KHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQ 1875
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
S+E EV AW+ L C R ++L+DT+D F+F +MVRDLL WM+ + R++ +QERP+DV
Sbjct: 1876 SKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDV 1935
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELL+ HQ +KAEI+ R +NF+ C+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1936 SSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMN 1995
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE R + L ++LEV QF+RDA+VAE+WL AQEPYL S+++G ++ KLIK+HEAFE
Sbjct: 1996 DKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFE 2055
Query: 6160 KSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTP 6303
KS + ERF ALEK TT ELKE Q E ETA H + R++P
Sbjct: 2056 KSTASWAERFAALEKPTTLELKERQTPERPTEEPGPQEEEGETAGEAPQVHHAATERTSP 2115
Query: 6304 AA 6309
+
Sbjct: 2116 VS 2117
>gi|34866100|ref|XP_234322.2| similar to Spectrin beta chain,
erythrocyte (Beta-I spectrin) [Rattus norvegicus]
Length = 2383
Score = 1863 bits (4825), Expect = 0.0
Identities = 969/2100 (46%), Positives = 1363/2100 (64%), Gaps = 12/2100 (0%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +D+SSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDSSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LP+PT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + ETRSAK+ALLLWCQMKTAGYP VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGRETRSAKDALLLWCQMKTAGYPQVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AFD AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+AE++REL L+ ELIRQEKLEQLA RF+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAEYQRELALRSELIRQEKLEQLARRFDRKAAMRETWLNENQRLVTQ 447
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I+ RK N+
Sbjct: 448 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRISARKNNIL 507
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ +LS + G HL++VEDLL
Sbjct: 508 RLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLL 567
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ + EL
Sbjct: 568 QKHKLMEADIAIQGDKVKTITAATLQF-----TEGKGYQPCDPQVIQDRVSHLEQCFSEL 622
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA RK +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 623 SNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 682
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L ++ +++ + G I R+ E+ + LKEL+A RK+ L
Sbjct: 683 EDELRGLDAHLKQIFQEAEDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDA 742
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH + +EL+ ++ L
Sbjct: 743 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHL 802
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL K ++ ++LR +L +AL LY ++ ++D+ E
Sbjct: 803 ENQAQGFPEEFRDSPDVTNRLQALRKLYQQVMAQAELRGHKLQEALDLYTVFGESDACEL 862
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EKGK L + +E++E+++HRFD L+Q+MK A++ VN A L+ HP S
Sbjct: 863 WMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRS 922
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q++LN RW + +V ++R ++ A R+ + +DC+ET WI DKT+V+E +
Sbjct: 923 GEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIVDKTKVVESTKD 982
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L DL+GV+ +QR+LS +ERD+ AI+ ++ +L +E+ + P + + I + + ++
Sbjct: 983 LGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPDQKEDIGQRQADVEKM 1042
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L ++ E L EA LQ FL+DLD F+AWL+ Q+ VASE+ P+SL EAEQLL Q
Sbjct: 1043 WKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQ 1102
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HAAI+EEID + +DY +++A G++V + QTDP Y L QRL GL W+ L RMW++R +
Sbjct: 1103 HAAIKEEIDAHKDDYHRVKASGEKVIEGQTDPDYQLLGQRLEGLDTDWDALWRMWESRGN 1162
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SL AE +++ +DF+ +M+ N +
Sbjct: 1163 TLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRD 1222
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K+ + G+ L +G+ ++KI +K + I++R N EKAQEV LKD L LQ FL +
Sbjct: 1223 KVLSPVDSGNMLVSEGNLYSNKIKEKVQLIEDRHMKNNEKAQEVTALLKDNLELQNFLQN 1282
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ + D +Y +A+ + +K+++HQAF +ELA+++ L+ + L +
Sbjct: 1283 CKELTLWINDKLLTSPDISYDEARNLHNKWMKHQAFMAELASHQGWLENIVAEGRQLMAE 1342
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L WDEL+ TT+ K ++L A L +Q+ AD+ +W + +E+++
Sbjct: 1343 KPQFTDVVSERLEALHKLWDELQTTTKAKTEQLSAARSSDLRLQTHADLSKWISAMEDQL 1402
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLTTVN M++ + ++ P ++
Sbjct: 1403 RSDDLGKDLTTVN-----------RMLRVEEQVNLRKEELEELFAEAPPLGAEAGDTDMS 1451
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE KA Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1452 IEKRFLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1511
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + + GQEL+ + E+++ L+S+W L+EA
Sbjct: 1512 FMKKNQTLQNEILGHAPRVEDVLHRGQELVKAAEIDCQDIEERLGHLQSSWDTLREAAAG 1571
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L E+ +A Q+ D GEAEAW+SEQELY+ DE KDE +K+H R Q +++
Sbjct: 1572 RLQRLREAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEE 1631
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA +A + P EQI Q Q++K YAGL+D + L
Sbjct: 1632 YGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRKLENMYHLFQL 1691
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI +KE+VA SQE GQD++HV ML+++F+ FAR+T IG ERV N N +
Sbjct: 1692 KREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVNSIIE 1751
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LN+ W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1752 RLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDE 1811
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +++ +G QV Q + A L+ YAG+KA I
Sbjct: 1812 KHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQ 1871
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
S+E EV AW+ L C R ++L+DT+D F+F +MVRDLL WM+ + R++ +QERP+DV
Sbjct: 1872 SKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDV 1931
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELL+ HQ +KAEI+ R +NF+ C+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1932 SSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMN 1991
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE R + L ++LEV QF+RDA+VAE+WL AQEPYL S+++G ++ KLIK+HEAFE
Sbjct: 1992 DKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFE 2051
Query: 6160 KSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTP 6303
KS + ERF ALEK TT ELKE Q E ETA H + R++P
Sbjct: 2052 KSTASWAERFAALEKPTTLELKERQTPDRPTEEPGPQEEEGETAGEAPQVHHAATERTSP 2111
Score = 97.8 bits (242), Expect = 3e-18
Identities = 54/121 (44%), Positives = 75/121 (61%), Gaps = 2/121 (1%)
Frame = +1
Query: 6361 EGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGC 6534
EG L RKH E ++KA+NRSW LY VLR ++L+FYKD K+ V HGE P+AL
Sbjct: 2237 EGYLGRKHDLEGPNKKASNRSWNNLYCVLRNSQLTFYKDAKNLALGVPYHGEEPLALRHA 2296
Query: 6535 SVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTL 6714
+A +Y+KKK+V LRL G+E+LF EE+M WL + A ++Q ++Q+L
Sbjct: 2297 ICEIAVNYKKKKHVFKLRLSNGSEWLFHGKDEEEMLLWLQGMSTAINESQSIRV-KAQSL 2355
Query: 6715 P 6717
P
Sbjct: 2356 P 2356
>gi|2506246|sp|P15508|SPCB_MOUSE Spectrin beta chain, erythrocyte
(Beta-I spectrin)
gi|2119258|pir||I52577 beta-spectrin - mouse
gi|440900|gb|AAB28600.1| beta-spectrin [Mus sp.]
Length = 2128
Score = 1838 bits (4760), Expect = 0.0
Identities = 959/2102 (45%), Positives = 1358/2102 (63%), Gaps = 12/2102 (0%)
Frame = +1
Query: 40 DEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKM 219
DE +DNSSARLFERSRIKALADERE+VQKKTFTKWVNSHL RVSC++ DLY D+RDG+M
Sbjct: 28 DELDNDNSSARLFERSRIKALADEREVVQKKTFTKWVNSHLARVSCRISDLYKDLRDGRM 87
Query: 220 LLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTL 399
L++LL VLSGE LP+PT GKMRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL L
Sbjct: 88 LIKLLEVLSGEMLPRPTKGKMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLVL 147
Query: 400 GLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
GLIWTIILRFQIQDI + + E RSAK+ALLLWCQMKTAGYP+VNV NF++SW+DGLA
Sbjct: 148 GLIWTIILRFQIQDIVVQTQEGREQRSAKDALLLWCQMKTAGYPHVNVTNFTSSWKDGLA 207
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIHKHRPDL+D+D L+ SNA +NL+ AFD AE QLG+ LD EDV + PDEKSII
Sbjct: 208 FNALIHKHRPDLIDFDKLKDSNARHNLEHAFDVAERQLGIIPLLDPEDVFTENPDEKSII 267
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYVV +YHYF+K+K ++GKR+GKVI+ +E +KMI +Y L+SDLL WI I +LN
Sbjct: 268 TYVVAFYHYFSKMKVLAVEGKRVGKVIDHAIETEKMIEKYSGLASDLLTWIEQTISVLNS 327
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L GVQ+QL F+ YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + P +GK
Sbjct: 328 RKFANSLSGVQQQLQAFSTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQKVYTPHDGK 387
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
L++DINRAW+SLE+AE++REL L+ ELIRQE F+RKA MRETWL ENQRLV+Q
Sbjct: 388 LVSDINRAWESLEEAEYQRELALRSELIRQE--------FDRKAAMRETWLNENQRLVTQ 439
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
DNFG DL++VEAA KKHEAIETD AYEER NYHDQ +I RK+N+
Sbjct: 440 DNFGYDLAAVEAAKKKHEAIETDTAAYEERVKALEDLAQELEKENYHDQKRIIARKDNIL 499
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
+RR RLE ++A+QK+F IK+ +LS + G HL++VEDLL
Sbjct: 500 RLWSYLQELLRSRRQRLEATLALQKLFQDMLHSIDWMDEIKAHILSAEFGKHLLEVEDLL 559
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
QKH L+E+DI I G++V A +F +G GY+P +P I +R L++ + EL
Sbjct: 560 QKHKLMEADIAIQGDKVKAITAATLQFA-----EGKGYQPCDPQVIQDRVSHLEQCFSEL 614
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++AA RK +LE +KRL +F+W++ E E IKE+EQ+ SS D G+D+ +V L KHK
Sbjct: 615 SNMAAGRKAQLEQSKRLWKFFWEMDEAESWIKEKEQIYSSLDYGKDLTSVLILQRKHKAF 674
Query: 2020 ENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
E+ LR L+ +L ++ ++ + G I R+ E+ + LKEL+A RK+ L
Sbjct: 675 EDELRGLDAHLKQIFQEADDMVAQKQFGHPQIETRVKEVSAQWDHLKELAAFRKKDLQDA 734
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
++QF DADD+ +L D R++S EDVG+DEG + L KKH + +EL+ ++ L
Sbjct: 735 ENFFQFQGDADDLKAWLQDAHRLLSGEDVGQDEGATRALGKKHKEFLEELEESRGVMEHL 794
Query: 2380 HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVES 2559
+A+ P+E R+ PD+ RL K ++ ++LR +L +AL LY ++ ++D+ E
Sbjct: 795 EHQAQGFPEEFRDSPDVTNRLQALRKLYQQVLTQAELRGHKLQEALDLYTVFGESDACEL 854
Query: 2560 WIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS 2739
W+ EKGK L + +E++E+++HRFD L+Q+MK A++ VN A L+ HP S
Sbjct: 855 WMTEKGKWLDQMDIPNTLEDLEVVQHRFDILDQEMKTLMAQIDGVNLAANNLVESGHPRS 914
Query: 2740 DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDA 2919
++ Q++LN RW + +V ++R ++ A R+ + +DC+ET WI DKT+V+E +
Sbjct: 915 GEVKQYQDRLNKRWQAFQAVVSEQREAVDSALRVNNYCVDCEETSKWIMDKTKVVESTKD 974
Query: 2920 LTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
L DL+GV+ +QR+LS +ERD+ AI+ ++ +L +E+ + P++ + I + + ++
Sbjct: 975 LGQDLAGVIAIQRKLSGLERDVLAIRDRVSALERESQYLMESHPEQKEDIGQRQADVEKL 1034
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L ++ E L EA LQ FL+DLD F+AWL+ Q+ VASE+ P+SL EAEQLL Q
Sbjct: 1035 WKGLQDALQGQELSLGEASKLQAFLQDLDDFKAWLSMAQKAVASEDMPESLPEAEQLLQQ 1094
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
HAAI+EEID + +DY +++A G++V + QTDP Y L QRL GL W+ L+RMW++R +
Sbjct: 1095 HAAIKEEIDAHRDDYHRVKASGEKVIEGQTDPDYQLLGQRLEGLDTDWDALRRMWESRGN 1154
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L+Q L Q F +DAKQAE +LS QE LA + P SL AE +++ +DF+ +M+ N +
Sbjct: 1155 TLTQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLAAAEAGIRKFEDFLVSMENNRD 1214
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
KI + G++L +G+ ++KI +K + I++R N EKAQE LKD L LQ FL +
Sbjct: 1215 KILSPVDSGNKLVAEGNLYSNKIMEKVQLIEDRHKKNNEKAQEATVLLKDNLELQNFLQN 1274
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
C EL WI +K++ + D +Y +A+ + +K+++HQAF +ELA+++ L+ + L +
Sbjct: 1275 CKELTLWINDKLLTSPDVSYDEARNLHNKWMKHQAFMAELASHQGWLENIDAEGRQLMAE 1334
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
KP++ + ++E L W+EL+ T + K ++L A L +Q+ AD+ +W +E+++
Sbjct: 1335 KPQFKDVVSERLEALHKLWEELQSTAKAKAEQLSAARSSDLRLQTHADLNKWIGAMEDQL 1394
Query: 4180 TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA 4359
+D DLTTVN + K +E ++ + + ++ D ++
Sbjct: 1395 RSDDLGKDLTTVNRMLAKLKRVEEQVNLRKEELEELFADAPSLGAEAGDT-------DMS 1447
Query: 4360 VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHR 4539
++++ L PL R+K LE KA Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 1448 IEKRFLDLLEPLGRRKKQLELSKAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 1507
Query: 4540 LQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKD 4719
K Q L NEI H P + + GQEL+ + E+++ L+S+W L+EA
Sbjct: 1508 FMKKNQTLQNEILGHAPRVEDVLRRGQELVKAAEIDCQDIEERLGHLQSSWDTLREAAAG 1567
Query: 4720 RKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDK 4899
R L ++ +A Q+ D GEAEAW+SEQELY+ DE KDE +K+H R Q +++
Sbjct: 1568 RLQRLRDAHEAQQYYLDAGEAEAWISEQELYVFSDEPPKDEEGAIVMLKRHLRQQRTVEE 1627
Query: 4900 FADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYAL 5079
+ I+ LA +A + P EQI Q Q++K YAGL+D + L
Sbjct: 1628 YGRNIKQLAGRAQSLLSAGHPEGEQIIRLQGQVDKQYAGLKDMAEERRRRLENMYHLFQL 1687
Query: 5080 HREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
RE DDL QWI +KE+VA SQE GQD++HV ML+++F+ FAR+T IG ERV N +
Sbjct: 1688 KREADDLEQWITEKEMVASSQEMGQDFDHVTMLRDKFRDFARETGAIGQERVDNVTI-IE 1746
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
LI GH++A TIA WKD LN+ W +LLEL+DTR Q+L AS LH++++ + L I E
Sbjct: 1747 RLIDAGHSEAATIAEWKDGLNDMWADLLELIDTRMQLLAASYDLHRYFYTGTEILGLIDE 1806
Query: 5440 KTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
K +P+D+G D+S+ + R H + +++ +G QV Q + A L+ YAG+KA I
Sbjct: 1807 KHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKADAIQ 1866
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
S+E EV AW+ L C R ++L+DT+D F+F +MVRDLL WM+ + R++ +QERP+DV
Sbjct: 1867 SKEQEVSAAWQALLDACAGRRAQLVDTADKFRFFSMVRDLLSWMESIIRQIETQERPRDV 1926
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
S VELL+ HQ +KAEI+ R +NF+ C+ LG LL R+H AS EI +KL ++ + R EM
Sbjct: 1927 SSVELLLKYHQGIKAEINTRAKNFSTCLELGESLLQRQHQASDEIREKLQQVISRRQEMN 1986
Query: 5980 RRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
+WE R + L ++LEV QF+RDA+VAE+WL AQEPYL S+++G ++ KLIK+HEAFE
Sbjct: 1987 DKWEARSDRLHMLLEVCQFSRDASVAEAWLIAQEPYLASRDFGHTVDSVEKLIKRHEAFE 2046
Query: 6160 KSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTP 6303
KS + ERF ALEK TT ELKE Q E ETA H + R++P
Sbjct: 2047 KSTASWAERFAALEKPTTLELKERQTPERPTEEPGPQEEEGETAGEAPQVHHAATERTSP 2106
Query: 6304 AA 6309
+
Sbjct: 2107 VS 2108
>gi|47221201|emb|CAG13137.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2235
Score = 1833 bits (4748), Expect = 0.0
Identities = 967/2083 (46%), Positives = 1349/2083 (64%), Gaps = 20/2083 (0%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGK 216
DE+ D DNSSARLFERSRIKALADERE VQKKTFTKWVNS L RV C++ DLY+D+RDG+
Sbjct: 27 DEELDNDNSSARLFERSRIKALADEREAVQKKTFTKWVNSILSRVGCRISDLYLDLRDGR 86
Query: 217 MLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLT 396
ML++LL VLSGERLPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RL
Sbjct: 87 MLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLI 146
Query: 397 LGLIWTIILRFQIQDITFE--DADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LGLIWTIILRFQIQDI E AD ETRSAK+ALLLWCQMKTAGYPNVN+ NF+TSW+D
Sbjct: 147 LGLIWTIILRFQIQDIIVETGQADQKETRSAKDALLLWCQMKTAGYPNVNITNFTTSWKD 206
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
G+AFNALIHKHRPDLV+Y+NL++SN +NLQ+AF+ AE +LG+ K LD EDV + PDEK
Sbjct: 207 GMAFNALIHKHRPDLVEYNNLKRSNPTHNLQNAFNVAEQKLGVTKLLDPEDVFTENPDEK 266
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV +YHYF+K+KQ ++GKR+GKV+++ +E +KMIN+YETL+SDLL WI I +
Sbjct: 267 SIITYVVAFYHYFSKMKQLAVEGKRVGKVLDQAIETEKMINKYETLASDLLAWIEQTILV 326
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
L R N+L GVQ+QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQR + PR
Sbjct: 327 LKNRKLANSLTGVQQQLQAFNTYRTVEKPPKFQEKGNLEVLLFTIQSRMRANNQRVYTPR 386
Query: 1111 EGKLIADINR---------------AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNR 1245
EG L+ADIN+ AW LEKAEH+RE VL++ELIRQEKLEQ+A RF+R
Sbjct: 387 EGVLVADINKVMRTVPRCATGWTDGAWGRLEKAEHDRERVLRDELIRQEKLEQMARRFDR 446
Query: 1246 KAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXX 1425
KA MRETWL ENQRLV+QDNFG DLS+VEAA KKH+AIETDI A+EER
Sbjct: 447 KAAMRETWLLENQRLVAQDNFGYDLSAVEAAKKKHDAIETDIAAFEERVQALVNISKELE 506
Query: 1426 XXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKS 1605
YHD +I+ RK+N+ RR RL+ ++++Q+IF +K+
Sbjct: 507 SERYHDAKRIDVRKDNILRLWDYLQELLKGRRGRLDKNLSLQRIFQEMLYIISWMDDMKA 566
Query: 1606 RLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVE 1785
RL+S D G HL++VEDLLQKHALLE DI + ERV N+ A A +F N G YKP +
Sbjct: 567 RLMSPDFGKHLLEVEDLLQKHALLEKDIALQAERVQNASAAALKFAN-----GDTYKPCD 621
Query: 1786 PGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTD 1965
P I +R L Y+EL LAA+R+ LE ++R F W+V EL+ I+E+E + SS D
Sbjct: 622 PQVIHDRVQHLDLCYQELCSLAAQRRAHLEQSRRFWNFLWEVVELDGWIREKEHIFSSLD 681
Query: 1966 TGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDY 2145
G+D+ +V L +KH E+ L L+++ G+E+ GS + L IR
Sbjct: 682 YGKDLTSVLVLQSKHGAFEDELAARRANLEQVVPEGEEMVRSEHLGSPKVQEALENIRRQ 741
Query: 2146 INKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKK 2325
+L+EL+A RK+ L ++QF DADD+ +L + R MSS+DVG DE T Q LLKK
Sbjct: 742 WQQLEELAAFRKQNLQDTQRFFQFQGDADDLRAWLLEAKRQMSSDDVGHDEYTTQRLLKK 801
Query: 2326 HDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRL 2505
H+ + +E I L +A +LP+E + PDI++RL EL +L+ LR+++L
Sbjct: 802 HNGLKNEAAKNGATIDALSKQANALPEELQNTPDIQRRLKDIKDLYMELMSLADLRQKKL 861
Query: 2506 IDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKV 2685
D ++LY ++S+ D+ E W+ +K L L +E++E++++R L QDM N +A+V
Sbjct: 862 DDTMALYTIFSETDACELWMGQKETWLVGLEVPDKLEDLEVVQNRLSMLAQDMGNMQARV 921
Query: 2686 TNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQ 2865
VN +QL HP + ++ Q +LN RW + MV+ K+ +++ A L + ++C
Sbjct: 922 EEVNKAVKQLEESRHPRTKEVKDCQARLNKRWEAFKAMVEDKKRKVDSAVSLNNYGLECD 981
Query: 2866 ETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERE 3045
ET WI DKTRV++ + L NDL+ VM +QR+L MERDL AI AKLD L EAD + R+
Sbjct: 982 ETDAWIRDKTRVIQSTQDLGNDLAAVMTIQRKLFGMERDLAAIGAKLDFLRDEADRLARD 1041
Query: 3046 RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV 3225
P+ A I + + + WD L K +++ E L E LQ FL+D+D FQ+WL TQ+ V
Sbjct: 1042 HPENAGDILKRRAELDKAWDDLKKTLKDREDSLGEVSKLQTFLQDMDDFQSWLYKTQKAV 1101
Query: 3226 ASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQ-TDPQYMFLRQRL 3402
ASEE P +L EAEQ L+ H A+RE+I + EDY ++R G RVT+ Q DPQY L QRL
Sbjct: 1102 ASEEIPATLPEAEQQLSLHDAMREDISNHEEDYHRVRDTGARVTRGQEEDPQYQQLEQRL 1161
Query: 3403 AGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQA 3582
GL GW ELQ+MWD+R++ L QGL Q F RD K E +L+ QE LA + P +L A
Sbjct: 1162 HGLDRGWYELQKMWDSRKNFLDQGLGFQQFSRDCKAVEAILNNQEYTLAHMEQPDTLAGA 1221
Query: 3583 ENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKA 3762
E K+H+DF++TMDAN++KI G +L + + + K +I +R N+ +A
Sbjct: 1222 EAASKKHEDFVSTMDANEDKIDGALQSGQRLVDSDNLYSANVRDKMDSIRDRHSKNKSRA 1281
Query: 3763 QEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELA 3942
QEV ++L+D LQ FL + +L WI EKM+ AQD +Y +A+ + SK+++HQAF +ELA
Sbjct: 1282 QEVSQRLRDNRDLQHFLQNTQDLTLWINEKMLTAQDTSYDEARNLHSKWLKHQAFMAELA 1341
Query: 3943 ANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQL 4122
ANK L ++ L + KPE+ + ++ +L WDELE TT+EK + LFDANR +L
Sbjct: 1342 ANKGWLQKVDQQGQALMEAKPEFEPIVRERLAKLHQLWDELEFTTQEKARLLFDANRSEL 1401
Query: 4123 YVQSIADMKEWATQLENEM-TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXX 4299
+ QS+AD+K+W +L+ ++ + +++ DLT+ N+ ++K + E ++ +A+ ++
Sbjct: 1402 FDQSLADVKKWLGELQQQLQSGDEEVKDLTSANILLKKHQMTENQVRDRARELEELQEAG 1461
Query: 4300 XXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWIS 4479
D+ E ++A A+Q + Q+L PL+ RR L+ KA QF RD+ +E LWI
Sbjct: 1462 RKHGGAREDQPE-LEAELQALQGEFQQLLTPLEQRRGKLDASKAVHQFYRDLANELLWIQ 1520
Query: 4480 ERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAF 4659
ER+ LA +Q G +L L K Q+ + + G GPA
Sbjct: 1521 ERMPLAMSQEHGHNLQSVQMLLKRNQVGARRAEG-----------------AGGRLGPAA 1563
Query: 4660 EKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKD 4839
+ +Q +G L S A Q+ D EAEAW+ EQELYM+ +E+ KD
Sbjct: 1564 GRDVQ---------------AQGRLDGSNLAQQYYNDADEAEAWIWEQELYMIAEEKAKD 1608
Query: 4840 EFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGL 5019
E S +K+H L+ D+D +AD+I+ L+ +A + ++ P E I RQ Q++K YAGL
Sbjct: 1609 EQSAMLMLKRHTILKQDVDDYADSIQKLSDRAQRMFAQEHPHGEDIIRRQGQVDKQYAGL 1668
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQF 5199
++ + L RE++DL WI+++++VA SQE GQD +HV +L+++F++F
Sbjct: 1669 RELAEDRRRKLDHTYHHFLLSREVEDLEHWISERDLVASSQEMGQDLDHVTLLRDKFREF 1728
Query: 5200 ARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEA 5379
AR+T +G ERV N D LI GH +A +A WKD +NE+W +LLEL+DTR Q+L
Sbjct: 1729 ARETGMVGQERVDLVNLTIDELIEAGHAEAAAMAEWKDGINESWADLLELIDTRTQLLAT 1788
Query: 5380 SRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQI 5559
S L +++ D ++ + +I +K +P+DLG D S + R H + +DI A+G+QV Q
Sbjct: 1789 SYELLRYFDDGKELVVQIQDKLKELPEDLGEDFSKAESFHRMHAAFERDITALGQQVQQF 1848
Query: 5560 ERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDL 5739
+ A+ L YAG +A I + E EV +AW+ L CD R ++L+DT++ F+F VR+L
Sbjct: 1849 QETASRLHTQYAGSRADSIRAAEREVAEAWKGLLDACDGRRAQLVDTAEKFRFFTAVREL 1908
Query: 5740 LLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHY 5919
+ WM+ + +++ + E+P+DVS VELL HQ + +EI+ARE F AC+ LG+ LL R+H
Sbjct: 1909 MAWMESIIQQIETPEKPRDVSSVELLQKYHQGICSEIEAREAKFAACVQLGQTLLTRQHR 1968
Query: 5920 ASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISK 6099
S+EIE+KL++L ++ EM+ + ++RW++L+L+LEV QFARDA+VAE+WL AQEPY+ S+
Sbjct: 1969 DSAEIEEKLLQLREKKEEMLLKRDERWDWLRLLLEVCQFARDASVAEAWLIAQEPYVTSR 2028
Query: 6100 EYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKE 6228
E G ++ + KL+++HEAFEKS EERF ALE+LTT L+E
Sbjct: 2029 ELGFSVHQVDKLLRRHEAFEKSTAMWEERFSALERLTTAVLQE 2071
Score = 294 bits (752), Expect = 2e-77
Identities = 271/1349 (20%), Positives = 557/1349 (41%), Gaps = 14/1349 (1%)
Frame = +1
Query: 2239 DRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEA-R 2415
+ +L + R+++ ++ G D V+ KKHD + ++ F++ ++ L ++ L E
Sbjct: 452 ETWLLENQRLVAQDNFGYDLSAVEAAKKKHDAIETDIAAFEERVQALVNISKELESERYH 511
Query: 2416 EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATL 2595
+ I R D L+ L+ L + R+ RL LSL +++ + + SW+D+ L +
Sbjct: 512 DAKRIDVRKDNILRLWDYLQELLKGRRGRLDKNLSLQRIFQEMLYIISWMDDMKARLMSP 571
Query: 2596 VPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE--HPNSDDILH-RQNK 2766
G+ + EVE + + LE+D+ Q +V N + A + N + P ++H R
Sbjct: 572 DFGKHLLEVEDLLQKHALLEKDIALQAERVQNASAAALKFANGDTYKPCDPQVIHDRVQH 631
Query: 2767 LNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVM 2946
L+ + +L + Q+R LE++ R F + E WI +K + D DL+ V+
Sbjct: 632 LDLCYQELCSLAAQRRAHLEQSRRFWNFLWEVVELDGWIREKEHIFSSLD-YGKDLTSVL 690
Query: 2947 KLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVR 3126
LQ + E +L A +A L+ + E +++ R + ++E ++ I + W L +
Sbjct: 691 VLQSKHGAFEDELAARRANLEQVVPEGEEMVRSEHLGSPKVQEALENIRRQWQQLEELAA 750
Query: 3127 EHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEID 3306
+ L + +F D D +AWL +RQ++S++ ++LL +H ++ E
Sbjct: 751 FRKQNLQDTQRFFQFQGDADDLRAWLLEAKRQMSSDDVGHDEYTTQRLLKKHNGLKNEAA 810
Query: 3307 GYAEDYKKMRAMGDRVTQD-QTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNL 3483
+ + + ++ Q P +++RL +++ + EL + D RQ L + L
Sbjct: 811 KNGATIDALSKQANALPEELQNTPD---IQRRLKDIKDLYMELMSLADLRQKKLDDTMAL 867
Query: 3484 QMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMF 3663
+ E+ + Q+E +L ++P LE E R M ++ V
Sbjct: 868 YTIFSETDACELWMGQKETWLVGLEVPDKLEDLEVVQNRLSMLAQDMGNMQARVEEVNKA 927
Query: 3664 GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI 3843
QL + H ++ +++R A + ++ +K+ A+SL + +CDE WI
Sbjct: 928 VKQLEESRHPRTKEVKDCQARLNKRWEAFKAMVEDKKRKVDSAVSLNNYGLECDETDAWI 987
Query: 3844 EEK--MIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHG 4017
+K +I++ + D + + + + +LAA +LD L+ A L D PE G
Sbjct: 988 RDKTRVIQSTQDLGNDLAAVMTIQRKLFGMERDLAAIGAKLDFLRDEADRLARDHPENAG 1047
Query: 4018 TIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP 4197
I + EL WD+L+KT +++ L + ++ Q ++Q + D + W + + + E+ P
Sbjct: 1048 DILKRRAELDKAWDDLKKTLKDREDSLGEVSKLQTFLQDMDDFQSWLYKTQKAVASEEIP 1107
Query: 4198 GDLTTVNVAMQKQHLIETEMIKKAQ--HIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQ 4371
L + + ++ + H + + ++ +
Sbjct: 1108 ATLPEAEQQLSLHDAMREDISNHEEDYHRVRDTGARVTRGQEEDPQYQQLEQRLHGLDRG 1167
Query: 4372 LQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKN 4551
LQ D R+ L++ QF RD + ++ + ++L K
Sbjct: 1168 WYELQKMWDSRKNFLDQGLGFQQFSRDCKAVEAILNNQEYTLAHMEQPDTLAGAEAASKK 1227
Query: 4552 LQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGD 4731
+ + +D +E I+ +GQ L+D + K+ +R + K ++
Sbjct: 1228 HEDFVSTMDANEDKIDGALQSGQRLVDSDNLYSANVRDKMDSIRDRHSKNKSRAQEVSQR 1287
Query: 4732 LGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADT 4911
L ++ FL + + W++E+ L QD + + ++ KH+ +++
Sbjct: 1288 LRDNRDLQHFLQNTQDLTLWINEKML-TAQDTSYDEARNLHSKWLKHQAFMAELAANKGW 1346
Query: 4912 IRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREI 5091
++ + + +E K ++ R A++ +L+ L+ + +
Sbjct: 1347 LQKVDQQGQALMEAKPEFEPIVRERLAKLHQLWDELEFTTQEKARLLFDANRSELFDQSL 1406
Query: 5092 DDLLQWIAD-KEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLI 5268
D+ +W+ + ++ + E +D +L ++ Q TEN +R + +
Sbjct: 1407 ADVKKWLGELQQQLQSGDEEVKDLTSANILLKKHQM----TENQVRDRARELEELQEAGR 1462
Query: 5269 GHG--HTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
HG D P + +L ++ LL ++ R L+AS+ +H+FY D + L I E+
Sbjct: 1463 KHGGAREDQPELEAELQALQGEFQQLLTPLEQRRGKLDASKAVHQFYRDLANELLWIQER 1522
Query: 5443 TH-AMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
AM + G + SV L +++Q +G
Sbjct: 1523 MPLAMSQEHGHNLQSVQMLLKRNQ----------------------------------VG 1548
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFK-FMNMVRDLLLWMDEVKREMNSQERPKD 5796
+R +E D + +D S+L + + N + W+ E + M ++E+ KD
Sbjct: 1549 ARRAEGAGGRLGPAAGRDVQAQGRLDGSNLAQQYYNDADEAEAWIWEQELYMIAEEKAKD 1608
Query: 5797 VSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEM 5976
L++ H LK ++D ++ + + ++H +I ++ ++ + A +
Sbjct: 1609 EQSAMLMLKRHTILKQDVDDYADSIQKLSDRAQRMFAQEHPHGEDIIRRQGQVDKQYAGL 1668
Query: 5977 MRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
EDR L + +R+ E W+ ++ S+E G++L+ L K F
Sbjct: 1669 RELAEDRRRKLDHTYHHFLLSREVEDLEHWISERDLVASSQEMGQDLDHVTLLRDKFREF 1728
Query: 6157 EKSAFAQEERFLALEKLTTFELKETQHRE 6243
+ + + L LT EL E H E
Sbjct: 1729 ARETGMVGQERVDLVNLTIDELIEAGHAE 1757
Score = 177 bits (450), Expect = 2e-42
Identities = 160/686 (23%), Positives = 308/686 (44%), Gaps = 8/686 (1%)
Frame = +1
Query: 1654 LLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYK 1833
LL+KH + E+ +V + + + + G G + +P ++ LQ ++
Sbjct: 1436 LLKKHQMTEN-------QVRDRARELEELQEAGRKHG-GAREDQP-ELEAELQALQGEFQ 1486
Query: 1834 ELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHK 2013
+LL +R+ +L+ +K + QF+ D+A I+E+ + S + G ++ +V LL K
Sbjct: 1487 QLLTPLEQRRGKLDASKAVHQFYRDLANELLWIQERMPLAMSQEHGHNLQSVQMLL---K 1543
Query: 2014 NAENNLRDLEKYLDRLD-VSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERL 2190
+ R E RL +G+++Q + RL
Sbjct: 1544 RNQVGARRAEGAGGRLGPAAGRDVQAQG------------------------------RL 1573
Query: 2191 AGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHI 2370
G Q++ DAD+ + ++++ M +E+ KDE + L+LK+H + ++ ++ I
Sbjct: 1574 DGSNLAQQYYNDADEAEAWIWEQELYMIAEEKAKDEQSAMLMLKRHTILKQDVDDYADSI 1633
Query: 2371 KVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSD 2541
+ L +A+ + A+EHP DI +R KQ A L L++ R+++L + L +
Sbjct: 1634 QKLSDRAQRM--FAQEHPHGEDIIRRQGQVDKQYAGLRELAEDRRRKLDHTYHHFLLSRE 1691
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL--EQDMKNQEAKVTNVNDLARQL 2715
+ +E WI E+ + ++ G+D++ V +++ +F E M QE +V VN +L
Sbjct: 1692 VEDLEHWISERDLVASSQEMGQDLDHVTLLRDKFREFARETGMVGQE-RVDLVNLTIDEL 1750
Query: 2716 LNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKT 2895
+ H + + ++ +N WA L +++D + L ++ L + D +E V I+DK
Sbjct: 1751 IEAGHAEAAAMAEWKDGINESWADLLELIDTRTQLLATSYELLRYFDDGKELVVQIQDKL 1810
Query: 2896 RVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERP-QEAQAIR 3072
+ L + L D S R + ERD+ A+ ++ + A + + A +IR
Sbjct: 1811 KELPED--LGEDFSKAESFHRMHAAFERDITALGQQVQQFQETASRLHTQYAGSRADSIR 1868
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
+ + + W L A+L + + RF + AW+ + +Q+ + E+P+ +
Sbjct: 1869 AAEREVAEAWKGLLDACDGRRAQLVDTAEKFRFFTAVRELMAWMESIIQQIETPEKPRDV 1928
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRV-TQDQTDPQYMFLRQRLAGLQEGWEE 3429
+ E L H I EI+ + +G + T+ D + ++L L+E EE
Sbjct: 1929 SSVELLQKYHQGICSEIEAREAKFAACVQLGQTLLTRQHRDSAE--IEEKLLQLREKKEE 1986
Query: 3430 LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQD 3609
+ D R L L + F RDA AE L QE Y+ ++ S+ Q + L+RH+
Sbjct: 1987 MLLKRDERWDWLRLLLEVCQFARDASVAEAWLIAQEPYVTSRELGFSVHQVDKLLRRHEA 2046
Query: 3610 FITTMDANDEKIRAVGMFGDQLCQDG 3687
F + +E+ A+ + Q+G
Sbjct: 2047 FEKSTAMWEERFSALERLTTAVLQEG 2072
Score = 41.2 bits (95), Expect = 0.36
Identities = 32/107 (29%), Positives = 49/107 (44%)
Frame = +1
Query: 5941 KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLE 6120
+L K +R ++R R E L+ + +F R AA+ E+WL + + +G +L
Sbjct: 415 RLEKAEHDRERVLRDELIRQEKLEQMAR--RFDRKAAMRETWLLENQRLVAQDNFGYDLS 472
Query: 6121 ETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
KKH+A E A EER AL ++ KE + AKR
Sbjct: 473 AVEAAKKKHDAIETDIAAFEERVQALVNIS----KELESERYHDAKR 515
>gi|40216167|gb|AAR82828.1| AT24411p [Drosophila melanogaster]
Length = 1410
Score = 1634 bits (4230), Expect = 0.0
Identities = 823/1395 (58%), Positives = 1049/1395 (74%), Gaps = 4/1395 (0%)
Frame = +1
Query: 16 GNSGAYTQDEDYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDL 192
G Y + +YD NSS+RLFERSRIKALA+ERE VQKKTFTKWVNSHL RV+C++ DL
Sbjct: 15 GPGNEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADL 74
Query: 193 YMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDI 372
Y+DMRDGK L++LL VLSGERLPKPT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDI
Sbjct: 75 YVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDI 134
Query: 373 VDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNF 552
VDGN+ L LGLIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF
Sbjct: 135 VDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNF 194
Query: 553 STSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNV 732
+TSWRDGLAFNA+IHKHRPDLV ++ L K+NA++NL +AFD AE++LGLAK LDAEDV V
Sbjct: 195 TTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFV 254
Query: 733 DQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWI 912
+ PDEKSIITYVVTYYHYF+KLKQ+ +QGKRIGKV+ MENDKM++ YE +SDLL+WI
Sbjct: 255 EHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWI 314
Query: 913 NAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQ 1092
IQ L ER FEN+L GVQ QL +F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ
Sbjct: 315 ETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQ 374
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
+P+ P+EGK+I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARF+RKA MRETWL
Sbjct: 375 KPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWL 434
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
+ENQRLVSQDNFG DL++VEAA KKHEAIETDIFAYEER YHD +
Sbjct: 435 SENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKR 494
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I RK+NV ARR+RLE+S+ +Q+ F IK L+++D G
Sbjct: 495 ILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGK 554
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HLM VEDLLQKH+L+E+DINI+GERV + +Q+F + D YKP +P I R
Sbjct: 555 HLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLS---DDPESYKPCDPEIIVSRVQ 611
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
L+ Y EL+ LA ER+ RLE++++L QF+WD A+ E+ IKE+EQ++S+ + G D+ TV+
Sbjct: 612 QLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVN 671
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSA 2172
+L+KHK E+ + + L + G EL E G+D I RL EI + + L +L+
Sbjct: 672 LMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTK 731
Query: 2173 SRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQ 2352
R++RL VEY+Q F DADDVD ++ DTLR++SSEDVG+DE VQ LLKKH DV DEL+
Sbjct: 732 YRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELK 791
Query: 2353 NFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKL 2532
N+ + I LH +AESL E ++ +RL+ + EL L++LRKQRL+DALSLYKL
Sbjct: 792 NYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKL 851
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
S+AD VE WI EK K+L T+ PG+DIE+VEIMKHRF+ +++M ++V VN LARQ
Sbjct: 852 MSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQ 911
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
LL+VEHPNSD+IL RQN LN W+ LR+ + K ++L+ AH ++TF I+C+ET++WIEDK
Sbjct: 912 LLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDK 971
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
R+L ++D+L DL+GVM LQRRLS M+RDL AIQAKL SL +EA+ IE E P+EA+ IR
Sbjct: 972 KRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIR 1031
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
E I +I +W+ L + ++E ++KL+EAGDL RFLRDLDHFQ WLT TQ VASE+ P SL
Sbjct: 1032 ERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSL 1091
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD---QTDPQYMFLRQRLAGLQEGW 3423
EAE+LLNQH +IREEID Y EDYK M G+R+T + DPQYMFLR+RL L++GW
Sbjct: 1092 PEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGW 1151
Query: 3424 EELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRH 3603
EEL +MW+NRQ LLSQ L+ Q+F RDA+Q EV+LSQQE++L+KDD P +LEQAENQLKRH
Sbjct: 1152 EELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRH 1211
Query: 3604 QDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKL 3783
+ F+TTM+AND+KI + D L + H+ ADKI K+A NI RR NR++A + +KL
Sbjct: 1212 EAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKL 1271
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLD 3963
K+ + L +FL D +EL EW++EK +QDE+YR AKTI SK+ RHQAF++E+AANKERL
Sbjct: 1272 KNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLF 1331
Query: 3964 QLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIAD 4143
+ + +A L +KPE+ I+P+++ELA Q+D+LE T+EKG LFDANR+ L Q+ D
Sbjct: 1332 EAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDD 1391
Query: 4144 MKEWATQLENEMTRE 4188
+ + T LE ++ ++
Sbjct: 1392 IDSYITDLEKQIVKK 1406
Score = 255 bits (651), Expect = 1e-65
Identities = 209/943 (22%), Positives = 415/943 (43%), Gaps = 12/943 (1%)
Frame = +1
Query: 3469 QGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIR 3648
Q L + F + L+Q NY + P+ +E+ ++ + M AN++K
Sbjct: 319 QSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFT-LQSKMRANNQKPY 377
Query: 3649 AVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
++ D + A +++ K ER A RE E++++ K +F
Sbjct: 378 TPKE--GKMISDINKAWERLEKAEH---ERELALRE---ELIRQEKLEQLAARFDRKASM 429
Query: 3829 LREWIEEKM-IRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
W+ E + +QD D + + +H+A ++++ A +ER+ + L ++
Sbjct: 430 RETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERY 489
Query: 4006 EYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTR 4185
I + + + W L + + +L + + Q Q + + + +++ +
Sbjct: 490 HDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMT 549
Query: 4186 EDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQ 4365
+D L V +QK L+E ++ + + P+ + + +
Sbjct: 550 DDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSR 609
Query: 4366 -EQLQRLQAPLD----DRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPD 4530
+QL+ A L +RR LE + +QF D DE+ WI E+ + +G L
Sbjct: 610 VQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTT 669
Query: 4531 CHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEA 4710
+ + + L +EI +H+P + + G ELI EGH + +++E+ + W L +
Sbjct: 670 VNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDL 729
Query: 4711 VKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSD 4890
K R+ L + + Q D + + WM + + ++ G+DE + ++ +KKH+ + +
Sbjct: 730 TKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADE 789
Query: 4891 IDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXX 5070
+ +A+ I AL +A ++ + R I+ Y L +
Sbjct: 790 LKNYAEVIDALHKQAESLKLNEAE-KANVDKRLEAIDNRYKELTELAKLRKQRLLDALSL 848
Query: 5071 YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAND 5250
Y L E D + QWI +K + + G+D E V++++ RF+ F ++ N + RVA N
Sbjct: 849 YKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEM-NANASRVAVVNQ 907
Query: 5251 GCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSR 5430
L+ H ++ I ++ LN+ W L E + + L+++ + FY +CR+ +S
Sbjct: 908 LARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISW 967
Query: 5431 IMEKTHAM--PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDK 5604
I +K + D L D + V L R+ +D+AAI +++ +ER+A + D + ++
Sbjct: 968 IEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHP-EE 1026
Query: 5605 ALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQE 5784
A I R +++ W L + R S+L + DL +F+ + W+ + + ++ S++
Sbjct: 1027 AKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASED 1086
Query: 5785 RPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSE----IEKKLIK 5952
P + E L+N HQS++ EID E++ + G L + + + ++L
Sbjct: 1087 TPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNA 1146
Query: 5953 LTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIK 6132
L E+ + WE+R L L+ F RDA E L QE +L + NLE+
Sbjct: 1147 LKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAEN 1206
Query: 6133 LIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
+K+HEAF + A +++ L ++ +++ ++ KR
Sbjct: 1207 QLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKR 1249
Score = 234 bits (598), Expect = 2e-59
Identities = 191/977 (19%), Positives = 423/977 (42%), Gaps = 15/977 (1%)
Frame = +1
Query: 2239 DRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEARE 2418
+ +L + R++S ++ G D V+ KKH+ + ++ +++ ++ + A + L E+
Sbjct: 431 ETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDEL--ESER 488
Query: 2419 HPDIRQ---RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLA 2589
+ D+++ R D ++ L L + R+ RL +L L + + + + ++E +LL
Sbjct: 489 YHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLM 548
Query: 2590 TLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS------DDIL 2751
T G+ + VE + + +E D+ +V V +++ L+ + P S + I+
Sbjct: 549 TDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLS-DDPESYKPCDPEIIV 607
Query: 2752 HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTND 2931
R +L +A+L + ++R+ LE + +L F D + WI++K +++ +D + +D
Sbjct: 608 SRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVS-TDEVGHD 666
Query: 2932 LSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDIL 3111
L+ V + + +E ++ + +L ++ K ++ E A I++ +K I WD L
Sbjct: 667 LTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHL 726
Query: 3112 NKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAI 3291
+ +L+ A + + D D W+ T R V+SE+ + A + LL +H +
Sbjct: 727 LDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDV 786
Query: 3292 REEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
+E+ YAE + + + ++ + + +RL + ++EL + R+ L
Sbjct: 787 ADELKNYAEVIDALHKQAESLKLNEAEKANV--DKRLEAIDNRYKELTELAKLRKQRLLD 844
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
L+L + +A E + ++ L + +E E R + F M+AN ++
Sbjct: 845 ALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAV 904
Query: 3652 VGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL 3831
V QL H +D+I ++ ++++ REKA+ + LK A +Q F +C E
Sbjct: 905 VNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRET 964
Query: 3832 REWIEEK--MIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
WIE+K ++ D D + + R +LAA + +L L+ A ++ D+ P
Sbjct: 965 ISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHP 1024
Query: 4006 EYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTR 4185
E I +I ++ W++L + +E+ KL +A +++ + + W T+ + ++
Sbjct: 1025 EEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVAS 1084
Query: 4186 EDQPGDLTTVNVAMQKQHLIETEMIKKAQH----IDXXXXXXXXXXXXHPDELENIKAHR 4353
ED P L + + I E+ + ++ + ++
Sbjct: 1085 EDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERL 1144
Query: 4354 LAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
A+++ + L ++R+ L + F RD ++ +S++ + +L
Sbjct: 1145 NALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQA 1204
Query: 4534 HRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAV 4713
K + ++ ++ IN + L+++ H + K+ + + + ++
Sbjct: 1205 ENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRA 1264
Query: 4714 KDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDI 4893
D+ L K H+FL D E W+ E + QDE + + ++ +H+ +++I
Sbjct: 1265 LDQHEKLKNQVKLHEFLQDLEELAEWVQE-KYATSQDESYRSAKTIHSKWTRHQAFEAEI 1323
Query: 4894 DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXY 5073
+ + A + +EK + I+ + ++ K + L+
Sbjct: 1324 AANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREV 1383
Query: 5074 ALHREIDDLLQWIADKE 5124
+ + DD+ +I D E
Sbjct: 1384 LVQQTCDDIDSYITDLE 1400
Score = 199 bits (506), Expect = 8e-49
Identities = 207/1092 (18%), Positives = 446/1092 (39%), Gaps = 31/1092 (2%)
Frame = +1
Query: 3022 EADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAK--LDEAGDLQRFLRDLDHFQ 3195
+A+D+ E P E I + H + + V+ + A + + + D ++F
Sbjct: 248 DAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFT 307
Query: 3196 A----WLTATQRQVASEEEPQSLAEAEQLLNQHAAIR--EEIDGYAEDYKK---MRAMGD 3348
+ W+ T + + E SLA + L Q + R E+ + E + +
Sbjct: 308 SDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQS 367
Query: 3349 RVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQ--------MFLRDA 3504
++ + P + ++ + + WE L++ R+ L + L Q F R A
Sbjct: 368 KMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKA 427
Query: 3505 KQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQD 3684
E LS+ + +++D+ L E K+H+ T + A +E+++AV D+L +
Sbjct: 428 SMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESE 487
Query: 3685 GHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEE-KMIR 3861
++ +I + N+ E + +L+ +L LQQ + + + +EE K +
Sbjct: 488 RYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLL 547
Query: 3862 AQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQI-- 4035
D+ + + +H ++++ ER+ + + D PE + DP+I
Sbjct: 548 MTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIV 607
Query: 4036 ---EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDL 4206
++L + EL + E+ +L ++ + + AD + W + E ++ ++ DL
Sbjct: 608 SRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDL 667
Query: 4207 TTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQ 4386
TTVN+ + K +E+E+ + + IK + + L
Sbjct: 668 TTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLL 727
Query: 4387 APLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLS 4566
RR+ LE FQ D DD W+ + L + ++++G + L K + ++
Sbjct: 728 DLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVA 787
Query: 4567 NEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESE 4746
+E+ N+ I+ + + L A +K+++ + + ++EL E K RK L ++
Sbjct: 788 DELKNYAEVIDALHKQAESL-KLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDAL 846
Query: 4747 KAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALA 4926
++ + + E W+ E+ + GKD + + E +++ A + +
Sbjct: 847 SLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVN 906
Query: 4927 TKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQ 5106
A + + + P +++I RQ + + ++ L++ + E + +
Sbjct: 907 QLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETIS 966
Query: 5107 WIADKE-VVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHT 5283
WI DK+ ++ + D V LQ R RD I + ++++ +++
Sbjct: 967 WIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQA-KLSSLEREANSIEDEHPE 1025
Query: 5284 DAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME-KTHAMPD 5460
+A I + WE L +++ R LE + LH+F D + + + +T +
Sbjct: 1026 EAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASE 1085
Query: 5461 DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELR-DGYAGD--KALDIGSRES 5631
D L +HQ+ ++I E + L +G D + + + R +
Sbjct: 1086 DTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLN 1145
Query: 5632 EVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE 5811
+ W L + + R L + D F R + + + + ++ + P ++ E
Sbjct: 1146 ALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAE 1205
Query: 5812 LLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWE 5991
+ H++ ++A ++ N + + L+ + H+ + +I K+ +T R + +R
Sbjct: 1206 NQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRAL 1265
Query: 5992 DRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETI-KLIKKHEAFEKSA 6168
D+ E L+ +++++F +D W+ QE Y S++ +TI +H+AFE
Sbjct: 1266 DQHEKLKNQVKLHEFLQDLEELAEWV--QEKYATSQDESYRSAKTIHSKWTRHQAFEAEI 1323
Query: 6169 FAQEERFLALEK 6204
A +ER EK
Sbjct: 1324 AANKERLFEAEK 1335
Score = 189 bits (481), Expect = 6e-46
Identities = 178/963 (18%), Positives = 406/963 (41%), Gaps = 25/963 (2%)
Frame = +1
Query: 2767 LNARWAQLRDMVDQK----RNELERAHRLETF--RIDCQETV--TWIEDKTRVLEDSDAL 2922
+N W +L ++ R EL R +LE R D + ++ TW+ + R++ D
Sbjct: 388 INKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQ-DNF 446
Query: 2923 TNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVW 3102
DL+ V ++ +E D+ A + ++ ++ D++E ER + + I + ++W
Sbjct: 447 GFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLW 506
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
L + +R +L+ + LQ+ +++ + + ++ + +++ + L E LL +H
Sbjct: 507 TYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKH 566
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQDQT------DPQYMFLRQRLAGLQEGWEELQRMW 3444
+ + +I+ E K + + D DP+ + R+ L++ + EL R+
Sbjct: 567 SLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIV--SRVQQLEDAYAELVRLA 624
Query: 3445 DNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTM 3624
R+ L + L F D E + ++E ++ D++ L L +H+ + +
Sbjct: 625 VERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEI 684
Query: 3625 DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQ 3804
++D +++ V G +L +GH+ AD+I + + I + + + ++L++A+
Sbjct: 685 TSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYF 744
Query: 3805 QFLSDCDELREWIEEKM-IRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAA 3981
Q +D D++ W+ + + I + ++ RD + S +H+ EL E +D L A
Sbjct: 745 QLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQA 804
Query: 3982 INLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWAT 4161
+L ++ E +D ++E + ++ EL + + + Q+L DA + +++W
Sbjct: 805 ESLKLNEAE-KANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIK 863
Query: 4162 QLENEMTREDQPG-DLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXX-HPDELE 4335
+ + +M PG D+ V + + + EM A + HP+ E
Sbjct: 864 E-KTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDE 922
Query: 4336 NIKAHRLAVQEQL---QRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERL-VLAKA 4503
++ QE ++ +A +DD + A F + + WI ++ +L +
Sbjct: 923 ILERQNHLNQEWSTLREKAEAKMDDLKSA----HGVQTFYIECRETISWIEDKKRILTET 978
Query: 4504 QNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELR 4683
+L L LQ+ L + ++ + ++ + + DE ++I ++
Sbjct: 979 DSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIE 1038
Query: 4684 SAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQI 4863
W++L + +K+R L E+ H+FL D + W+++ + + ++ + +
Sbjct: 1039 LIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLL 1098
Query: 4864 KKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE-QIQVRQAQIEKLYAG---LQDXX 5031
+H+ ++ +ID + + + + + E S + Q + ++ L G L
Sbjct: 1099 NQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMW 1158
Query: 5032 XXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDT 5211
+R+ ++ +E + + E + +R + F
Sbjct: 1159 ENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFLTTM 1218
Query: 5212 ENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLL 5391
E +++ DTL+ H DA I +++ ++ + + + L+ L
Sbjct: 1219 E-ANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKL 1277
Query: 5392 HKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDA 5571
H+F D + + EK D+ R + ++ + +HQ + +IAA E++ + E+ A
Sbjct: 1278 HEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSA 1337
Query: 5572 AEL 5580
EL
Sbjct: 1338 QEL 1340
Score = 189 bits (480), Expect = 8e-46
Identities = 231/1170 (19%), Positives = 451/1170 (37%), Gaps = 57/1170 (4%)
Frame = +1
Query: 2626 IMKHRFDTLEQDMKNQEAKVTNVN---DLARQLLN-----------VEHPNSDDIL---- 2751
I KHR D ++ + ++ + N+N D+A L VEHP+ I+
Sbjct: 208 IHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVV 267
Query: 2752 ---HRQNKLNARWAQ---LRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDS 2913
H +KL Q + +V + H E F D + WIE + L +
Sbjct: 268 TYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDL---LKWIETTIQSLGER 324
Query: 2914 DALTNDLSGVMKLQRRLSMMER--------DLGAIQAKLDSLHKE--ADDIERERPQEAQ 3063
+ N L+GV + S + G ++ L +L + A++ + P+E +
Sbjct: 325 E-FENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGK 383
Query: 3064 AIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQ--------RFLRDLDHFQAWLTATQR 3219
I + I++ W+ L K E E L E Q RF R + WL+ QR
Sbjct: 384 MISD----INKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQR 439
Query: 3220 QVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQT-DPQYMFLRQ 3396
V+ + LA E +H AI +I Y E + + A+ D + ++ D + + LR+
Sbjct: 440 LVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRK 499
Query: 3397 RLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLE 3576
+ W L + R+ L L LQ ++ + + + L DD + L
Sbjct: 500 D--NVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLM 557
Query: 3577 QAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYA-----ADKIHKKARNIDERR 3741
E+ L++H ++ E+++ V + D + + I + + +++
Sbjct: 558 GVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAY 617
Query: 3742 GANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEK-MIRAQDETYRDAKTITSKFVRH 3918
A E +L+++ L QF D + WI+EK I + DE D T+ +H
Sbjct: 618 AELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKH 677
Query: 3919 QAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKL 4098
+A +SE+ ++ +L + L + I +++E+ +WD L T+ + Q+L
Sbjct: 678 KALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRL 737
Query: 4099 FDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHI 4278
+A D+ W ++ ED D V ++K + E+ A+ I
Sbjct: 738 ENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVI 797
Query: 4279 DXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVD 4458
D ++ N+ A+ + + L R++ L + ++ + D
Sbjct: 798 DALHKQAESLKLNEAEKA-NVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEAD 856
Query: 4459 DEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEG 4638
+ WI E+ + G+ + D ++ + E++ + + + ++L+
Sbjct: 857 GVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVE 916
Query: 4639 HANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMM 4818
H N ++ L W L+E + + DL + F +C E +W+ +++ +
Sbjct: 917 HPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILT 976
Query: 4819 Q-DERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
+ D D ++ + D+ + +L +A+ +E + I+ R AQ
Sbjct: 977 ETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQ 1036
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
IE ++ L + R++D W+ + S++ +
Sbjct: 1037 IELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEK 1096
Query: 5176 LQERFQQFARDTENIGSERVANANDGCDTLIGHGHT-DAPTIALWKDSLN---EAWENLL 5343
L + Q + +N +E N + + L G T D P ++ LN + WE L
Sbjct: 1097 LLNQHQSIREEIDNY-TEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELH 1155
Query: 5344 ELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKHQNYL 5520
++ + R +L S F D R + ++ H + DD + ++H+ +L
Sbjct: 1156 QMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFL 1215
Query: 5521 KDIAAIGEQVAQIERDAAEL--RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ A +++ + + A L +D + DK IG R + R + +L
Sbjct: 1216 TTMEANDDKINTLLQVADTLVEKDHFDADK---IGKRAENITGRRDDNRQRALDQHEKLK 1272
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
+ L +F+ + +L W+ E K + E + + HQ+ +AEI A +E
Sbjct: 1273 NQVKLHEFLQDLEELAEWVQE-KYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLF 1331
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTE 5964
++L K IE KL +L +
Sbjct: 1332 EAEKSAQELSKEKPEFKDVIEPKLKELAKQ 1361
Score = 126 bits (316), Expect = 8e-27
Identities = 124/554 (22%), Positives = 236/554 (42%), Gaps = 16/554 (2%)
Frame = +1
Query: 4651 PAFEKKIQELRSAWQELKEAVKDRKGDLGES--------EKAHQFLYDCGEAEAWMSEQE 4806
P K I ++ AW+ L++A +R+ L E + A +F E W+SE +
Sbjct: 379 PKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQ 438
Query: 4807 LYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVR 4986
+ QD G D + + KKHE +++DI + + ++A+ + E+ ++I +R
Sbjct: 439 RLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLR 498
Query: 4987 QAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEH 5166
+ + +L+ L + +E+ +L + + + + + + G+
Sbjct: 499 KDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMG 558
Query: 5167 VQMLQERFQQFARDTENIGSERVANANDGCDTLIG-----HGHTDAPTIALWKDSLNEAW 5331
V+ L ++ D NI ERV + + D I L +A+
Sbjct: 559 VEDLLQKHSLVEADI-NILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAY 617
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKH 5508
L+ L R LE SR L +FY D D + I EK + D++G D ++V + KH
Sbjct: 618 AELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKH 677
Query: 5509 QNYLKDIAAIGEQVAQIERDAAEL-RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTS 5685
+ +I + Q+ + + +EL +G+ G A I R E++ W HL L R
Sbjct: 678 KALESEITSHDPQLQNVAKVGSELITEGHFG--ADRIKDRLKEILNKWDHLLDLTKYRRQ 735
Query: 5686 RLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREE 5865
RL + + F+ D+ WM + R ++S++ +D + V+ L+ H+ + E+ E
Sbjct: 736 RLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAE 795
Query: 5866 NFNACISLGRDL-LNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFAR 6042
+A L LN A+ ++K+L + E+ + R + L L +Y+
Sbjct: 796 VIDALHKQAESLKLNEAEKAN--VDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMS 853
Query: 6043 DAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFEL 6222
+A E W+ + L + G+++E+ + + E F+K A R + +L L
Sbjct: 854 EADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLL 913
Query: 6223 KETQHREEETAKRR 6264
+E +R+
Sbjct: 914 HVEHPNSDEILERQ 927
>gi|30794220|ref|NP_115999.1| spectrin beta 4; beta-spectrin 4;
quivering; lumbosacral neuroaxonal dystrophy; neuroaxonal
dystrophy [Mus musculus]
gi|18147602|dbj|BAB83243.1| betaIV-spectrin sigma1 [Mus musculus]
Length = 2561
Score = 1546 bits (4004), Expect = 0.0
Identities = 867/2106 (41%), Positives = 1258/2106 (59%), Gaps = 28/2106 (1%)
Frame = +1
Query: 58 NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLA 237
N++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY D+RDG +L RLL
Sbjct: 42 NAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLE 101
Query: 238 VLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTI 417
VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGL+WTI
Sbjct: 102 VLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTI 161
Query: 418 ILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIH 597
ILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRDGLAFNALIH
Sbjct: 162 ILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIH 221
Query: 598 KHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTY 777
+HRPDLVD L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEKSIITYVV++
Sbjct: 222 RHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSF 281
Query: 778 YHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENN 957
YHYF+K+K ++GKRIGKV+++++E DK+I RYE L+++LL WI+ + L++ + F N+
Sbjct: 282 YHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYEELAAELLAWIHRTVDLISNQKFANS 341
Query: 958 LEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADIN 1137
L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA+N+R FVPREG I DI+
Sbjct: 342 LSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRAHNRRLFVPREGCGIWDID 401
Query: 1138 RAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGND 1317
+AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRLVSQDNFG +
Sbjct: 402 KAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYE 461
Query: 1318 LSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXX 1497
L +VEAA KKHEAIE DI AYEER Y+D ++ ++++V
Sbjct: 462 LPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDARRVAAQRDSVLRQWALL 521
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
ARR RLE ++A+QK+F ++++LLS + G HL++ +DLLQKH LL
Sbjct: 522 TGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQTQLLSRECGQHLVEADDLLQKHGLL 581
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E DI ERV A A RF GY+P +P I R + + EL + AA
Sbjct: 582 EGDIAAQSERVEALNAAALRFSQL-----QGYQPCDPQVICNRVNHVHGCLSELQEQAAR 636
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTD----------TGRDIVTVSHLLAK 2007
R+ LE ++ L ++ E E +++E++L +T D+ + + LLA+
Sbjct: 637 RRAELEASRSLWALLQELEEAESWARDKERLLEATSGSGGAAGTAGGAHDLSSTARLLAQ 696
Query: 2008 HKNAENNLRDLEKYLDRLDVSGKELQ---DESIPGSD-----NIPPRLAEIRDYINKLKE 2163
HK + L L + G+EL PG++ + R A R +L+E
Sbjct: 697 HKILQGELGGRRALLQQALRRGEELAAAGGSVGPGAEPLHLAGLAERAASARRRWQRLEE 756
Query: 2164 LSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHD 2343
+A R+ RL +QF D D + +L D R+ ++ D G DE + + L ++H +
Sbjct: 757 AAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTG 816
Query: 2344 ELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAELENLSQLRKQRLIDA 2514
E++ + L + +L + P ++ R+ + AE+ ++ LR+Q L DA
Sbjct: 817 EVEAHRGPVGGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDA 876
Query: 2515 LSLYKLYSDADSVESWIDEKGK-LLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTN 2691
L++Y+++ + + E WI EK + LLA VP +++VE+++HRF++L+Q+M + +V +
Sbjct: 877 LAVYRMFGEVHACELWIGEKEQWLLAMRVPD-SLDDVEVVQHRFESLDQEMNSLMGRVLD 935
Query: 2692 VNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQET 2871
VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+ +E ++ E
Sbjct: 936 VNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEV 995
Query: 2872 VTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERP 3051
+ +K R +E + LQ RLS +E L A++ + +L +EA + P
Sbjct: 996 RAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAALLEEAALLAERFP 1049
Query: 3052 QEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVAS 3231
+A + + + + W L + + AG LQRFLRDLD F WL Q +
Sbjct: 1050 AQATRLHQGAEELGAEWGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGA 1109
Query: 3232 EEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDP--QYMFLRQR 3399
E P+SL EA+ LL +HAA++EE+D EDY ++ A + + + + L +
Sbjct: 1110 VEGPLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLASEGAELGPGLALDEW 1169
Query: 3400 LAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQ 3579
L L+ GW +L +W+ R+ L Q Q+FLRD QA +L QE L+ ++P ++E
Sbjct: 1170 LPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQEVALSGAELPCTVES 1229
Query: 3580 AENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREK 3759
E +KRH+DF+TTM+ N +K++ + L + G+ ++ + + E+ N+ +
Sbjct: 1230 VEEAMKRHRDFLTTMELNQQKMQVAVQAAESLLRQGNAYGEQAQEAVARLLEKSQENQLR 1289
Query: 3760 AQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSEL 3939
AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D+ + +++RHQAF +EL
Sbjct: 1290 AQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSHKLHKRWLRHQAFMAEL 1349
Query: 3940 AANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQ 4119
A NKE L++++ L +KPE ++ ++ E+ W ELE TT+ K ++LF+A++
Sbjct: 1350 AQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKAD 1409
Query: 4120 LYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXX 4299
VQS A++ + +E+++ D GDL TVN ++K +E+++ + + +
Sbjct: 1410 QLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQT 1469
Query: 4300 XXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWIS 4479
+ E + + AV E+L RL PL +RR+ L K Q D+DDE W+
Sbjct: 1470 AALPLEQASK-ELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQ 1528
Query: 4480 ERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAF 4659
ERL LA G L + K Q L EI H P + ++ L A
Sbjct: 1529 ERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLASLRSPEAEAV 1588
Query: 4660 EKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKD 4839
+ ++L+SAW L+EA + R+ L + + Q+ +D E EAW+ EQEL MM +++GKD
Sbjct: 1589 RRGQEQLQSAWTGLREAAERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKD 1648
Query: 4840 EFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGL 5019
E ST +KKH +L+ ++ + ++I L+ + +E P +EQI RQ+Q+++LY L
Sbjct: 1649 EQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVAL 1708
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQF 5199
++ Y L R++D+L WIA+KEVVAGS E GQD+EHV +LQE+F +F
Sbjct: 1709 KELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEF 1768
Query: 5200 ARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEA 5379
A +T G ER+A N D LI GHT A T+A WKD LNEAW LLELM TRAQ+L A
Sbjct: 1769 ASETGTAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAA 1828
Query: 5380 SRLLHKFYHDCRDCLSRIMEKTHAMPDDLG--RDSSSVGALSRKHQNYLKDIAAIGEQVA 5553
SR LHKF+ D R+ +I EK +P S ++ R + + D+ + QV
Sbjct: 1829 SRELHKFFSDARELQGQIEEKRRRLPRLTAPPEPRPSASSMQRTLRAFEHDLQLLVSQVR 1888
Query: 5554 QIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVR 5733
Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ + T+D +F + R
Sbjct: 1889 QLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLAACEDARLHVSSTADALRFHSQAR 1948
Query: 5734 DLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRK 5913
DLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR AC LGR LL K
Sbjct: 1949 DLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELAACQELGRSLLLNK 2008
Query: 5914 HYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLI 6093
+ EI+ +L KL + + E+ +W+ WE+LQ +LEV+QFA++A VA++WL AQEP L
Sbjct: 2009 SAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQ 2068
Query: 6094 SKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPA 6273
S+E G +++E +LI++HEAF K+A A EERF +L +LTT E + + ++ G
Sbjct: 2069 SRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRK 2128
Query: 6274 HIGSPS 6291
G P+
Sbjct: 2129 FFGDPT 2134
Score = 91.7 bits (226), Expect = 2e-16
Identities = 63/150 (42%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2395 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGF 2453
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2454 YKDSKGPASGGTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2513
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA A+ E +R QTLP S
Sbjct: 2514 GWLE--AVANSVAEHAEIARWGQTLPTTSS 2541
>gi|11992162|gb|AAG42473.1| spectrin beta IV [Homo sapiens]
Length = 2564
Score = 1541 bits (3991), Expect = 0.0
Identities = 863/2119 (40%), Positives = 1258/2119 (58%), Gaps = 32/2119 (1%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH+HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF GY+P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFSQL-----QGYQPCDPQVICNRVNHVHGCL 626
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 627 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 686
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 687 GAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 746
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 747 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 806
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 807 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 866
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 867 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 926
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 927 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 986
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 987 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1040
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1041 LLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1100
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1101 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1160
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W+ R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1161 GAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQEM 1220
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1221 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1280
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D +
Sbjct: 1281 TRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDSTREDNHKLH 1340
Query: 3901 SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTE 4080
+++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W ELE TT+
Sbjct: 1341 KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQ 1400
Query: 4081 EKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMI 4260
K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K +E+++
Sbjct: 1401 AKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVE 1460
Query: 4261 KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQ 4440
+ + + P E + + AV E+L RL PL +RR+ L K Q
Sbjct: 1461 EWYREV-GELQAQTAALPLEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ 1519
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
D+DDE W+ ERL LA G L + K Q L EI H P + ++
Sbjct: 1520 VAHDLDDELAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAG 1579
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
L A + +++L+SAW L+EA + R+ L + + Q+ +D E EAW+ E
Sbjct: 1580 ALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGE 1639
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
QEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E P +EQI
Sbjct: 1640 QELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQIS 1699
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS E GQD+
Sbjct: 1700 RRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDF 1759
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD LNEAW L
Sbjct: 1760 EHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAEL 1819
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQN 5514
LELM TRAQ+L ASR LHKF+ D R+ +I EK +P S ++ R +
Sbjct: 1820 LELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRA 1879
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ +
Sbjct: 1880 FEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVS 1939
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
T+D +F + VRDLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR
Sbjct: 1940 STADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELT 1999
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
C LGR LL K + EI+ +L KL T + E+ +W+ WE+LQ +LEV+QFA++A V
Sbjct: 2000 TCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVV 2059
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQ 6234
A++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +L +LTT E + +
Sbjct: 2060 ADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKIKAE 2119
Query: 6235 HREEETAKRRGPAHIGSPS 6291
++ G G P+
Sbjct: 2120 QSKQPPTPLLGRKFFGDPT 2138
Score = 93.6 bits (231), Expect = 6e-17
Identities = 64/150 (42%), Positives = 83/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2398 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGF 2456
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K S HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2457 YKDSKGPASGSTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2516
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA+ A+ E +R QTLP S
Sbjct: 2517 GWLE--AVASSVAEHAEIARWGQTLPTTSS 2544
>gi|17368942|sp|Q9H254|SPCQ_HUMAN Spectrin beta chain, brain 3
(Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin)
Length = 2564
Score = 1541 bits (3989), Expect = 0.0
Identities = 863/2119 (40%), Positives = 1258/2119 (58%), Gaps = 32/2119 (1%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH+HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF GY+P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFSQL-----QGYQPCDPQVICNRVNHVHGCL 626
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 627 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 686
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 687 GAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 746
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 747 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 806
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 807 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 866
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 867 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 926
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 927 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 986
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 987 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1040
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1041 LLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1100
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1101 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1160
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W+ R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1161 GAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQEM 1220
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1221 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1280
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D +
Sbjct: 1281 TRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLH 1340
Query: 3901 SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTE 4080
+++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W ELE TT+
Sbjct: 1341 KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQ 1400
Query: 4081 EKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMI 4260
K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K +E+++
Sbjct: 1401 AKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVE 1460
Query: 4261 KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQ 4440
+ + + P E + + AV E+L RL PL +RR+ L K Q
Sbjct: 1461 EWYREV-GELQAQTAALPLEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ 1519
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
D+DDE W+ ERL LA G L + K Q L EI H P + ++
Sbjct: 1520 VAHDLDDELAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAG 1579
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
L A + +++L+SAW L+EA + R+ L + + Q+ +D E EAW+ E
Sbjct: 1580 ALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGE 1639
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
QEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E P +EQI
Sbjct: 1640 QELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQIS 1699
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS E GQD+
Sbjct: 1700 RRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDF 1759
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD LNEAW L
Sbjct: 1760 EHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAEL 1819
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQN 5514
LELM TRAQ+L ASR LHKF+ D R+ +I EK +P S ++ R +
Sbjct: 1820 LELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRA 1879
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ +
Sbjct: 1880 FEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVS 1939
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
T+D +F + VRDLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR
Sbjct: 1940 STADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELT 1999
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
C LGR LL K + EI+ +L KL T + E+ +W+ WE+LQ +LEV+QFA++A V
Sbjct: 2000 TCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVV 2059
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQ 6234
A++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +L +LTT E + +
Sbjct: 2060 ADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKIKAE 2119
Query: 6235 HREEETAKRRGPAHIGSPS 6291
++ G G P+
Sbjct: 2120 QSKQPPTPLLGRKFFGDPT 2138
Score = 93.6 bits (231), Expect = 6e-17
Identities = 64/150 (42%), Positives = 83/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2398 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGF 2456
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K S HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2457 YKDSKGPASGSTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2516
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA+ A+ E +R QTLP S
Sbjct: 2517 GWLE--AVASSVAEHAEIARWGQTLPTTSS 2544
>gi|16117405|gb|AAK38731.1| beta4-spectrin [Mus musculus]
gi|20372348|gb|AAK49014.1| beta-spectrin 4 [Mus musculus]
Length = 2555
Score = 1539 bits (3985), Expect = 0.0
Identities = 864/2106 (41%), Positives = 1255/2106 (59%), Gaps = 28/2106 (1%)
Frame = +1
Query: 58 NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLA 237
N++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY D+RDG +L RLL
Sbjct: 42 NAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLE 101
Query: 238 VLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTI 417
VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGL+WTI
Sbjct: 102 VLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTI 161
Query: 418 ILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIH 597
ILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRDGLAFNALIH
Sbjct: 162 ILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIH 221
Query: 598 KHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTY 777
+HRPDLVD L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEKSIITYVV++
Sbjct: 222 RHRPDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSF 281
Query: 778 YHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENN 957
YHYF+K+K ++GKRIGKV+++++E DK+I RYE L+++LL WI+ + L++ + F N+
Sbjct: 282 YHYFSKMKALAVEGKRIGKVLDQVLEVDKIIERYEELAAELLAWIHRTVDLISNQKFANS 341
Query: 958 LEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADIN 1137
L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA+N+R FVPREG I DI+
Sbjct: 342 LSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRAHNRRLFVPREGCGIWDID 401
Query: 1138 RAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGND 1317
+AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRLVSQDNFG +
Sbjct: 402 KAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYE 461
Query: 1318 LSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXX 1497
L +VEAA KKHEAIE DI AYEER Y+D ++ ++++V
Sbjct: 462 LPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDARRVAAQRDSVLRQWALL 521
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
ARR RLE ++A+QK+F ++++LLS + G HL++ +DLLQKH LL
Sbjct: 522 TGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQTQLLSRECGQHLVEADDLLQKHGLL 581
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E DI ERV A A RF +P +P I R + + EL + AA
Sbjct: 582 EGDIAAQSERVEALNAAALRFS----------QPCDPQVICNRVNHVHGCLSELQEQAAR 631
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTD----------TGRDIVTVSHLLAK 2007
R+ LE ++ L ++ E E +++E++L +T D+ + + LLA+
Sbjct: 632 RRAELEASRSLWALLQELEEAESWARDKERLLEATSGSGGAAGTAGGAHDLSSTARLLAQ 691
Query: 2008 HKNAENNLRDLEKYLDRLDVSGKELQ---DESIPGSD-----NIPPRLAEIRDYINKLKE 2163
HK + L L + G+EL PG++ + R A R +L+E
Sbjct: 692 HKILQGELGGRRALLQQALRRGEELAAAGGSVGPGAEPLHLAGLAERAASARRRWQRLEE 751
Query: 2164 LSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHD 2343
+A R+ RL +QF D D + +L D R+ ++ D G DE + + L ++H +
Sbjct: 752 AAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTG 811
Query: 2344 ELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAELENLSQLRKQRLIDA 2514
E++ + L + +L + P ++ R+ + AE+ ++ LR+Q L DA
Sbjct: 812 EVEAHRGPVGGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDA 871
Query: 2515 LSLYKLYSDADSVESWIDEKGK-LLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTN 2691
L++Y+++ + + E WI EK + LLA VP +++VE+++HRF++L+Q+M + +V +
Sbjct: 872 LAVYRMFGEVHACELWIGEKEQWLLAMRVPD-SLDDVEVVQHRFESLDQEMNSLMGRVLD 930
Query: 2692 VNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQET 2871
VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+ +E ++ E
Sbjct: 931 VNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEV 990
Query: 2872 VTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERP 3051
+ +K R +E + LQ RLS +E L A++ + +L +EA + P
Sbjct: 991 RAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAALLEEAALLAERFP 1044
Query: 3052 QEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVAS 3231
+A + + + + W L + + AG LQRFLRDLD F WL Q +
Sbjct: 1045 AQATRLHQGAEELGAEWGALAGAAQACGEAVAAAGRLQRFLRDLDTFLDWLVRAQEAAGA 1104
Query: 3232 EEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDP--QYMFLRQR 3399
E P+SL EA+ LL +HAA++EE+D EDY ++ A + + + + L +
Sbjct: 1105 VEGPLPRSLEEADGLLARHAALKEEVDQREEDYARIVAASEALLASEGAELGPGLALDEW 1164
Query: 3400 LAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQ 3579
L L+ GW +L +W+ R+ L Q Q+FLRD QA +L QE L+ ++P ++E
Sbjct: 1165 LPHLEVGWHKLLGLWEERREALVQAHVYQLFLRDLCQALAVLRNQEVALSGAELPCTVES 1224
Query: 3580 AENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREK 3759
E +KRH+DF+TTM+ N +K++ + L + G+ ++ + + E+ N+ +
Sbjct: 1225 VEEAMKRHRDFLTTMELNQQKMQVAVQAAESLLRQGNAYGEQAQEAVARLLEKSQENQLR 1284
Query: 3760 AQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSEL 3939
AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D+ + +++RHQAF +EL
Sbjct: 1285 AQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLMARDGTREDSHKLHKRWLRHQAFMAEL 1344
Query: 3940 AANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQ 4119
A NKE L++++ L +KPE ++ ++ E+ W ELE TT+ K ++LF+A++
Sbjct: 1345 AQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQLFEASKAD 1404
Query: 4120 LYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXX 4299
VQS A++ + +E+++ D GDL TVN ++K +E+++ + + +
Sbjct: 1405 QLVQSFAELDKRLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWCREVGELQAQT 1464
Query: 4300 XXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWIS 4479
+ E + + AV E+L RL PL +RR+ L K Q D+DDE W+
Sbjct: 1465 AALPLEQASK-ELVGERQSAVGERLVRLLEPLQERRRLLLASKELHQVAHDLDDELAWVQ 1523
Query: 4480 ERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAF 4659
ERL LA G L + K Q L EI H P + ++ L A
Sbjct: 1524 ERLPLAMQTERGTGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGVLASLRSPEAEAV 1583
Query: 4660 EKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKD 4839
+ ++L+SAW L+EA + R+ L + + Q+ +D E EAW+ EQEL MM +++GKD
Sbjct: 1584 RRGQEQLQSAWTGLREAAERRQQTLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKD 1643
Query: 4840 EFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGL 5019
E ST +KKH +L+ ++ + ++I L+ + +E P +EQI RQ+Q+++LY L
Sbjct: 1644 EQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVAL 1703
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQF 5199
++ Y L R++D+L WIA+KEVVAGS E GQD+EHV +LQE+F +F
Sbjct: 1704 KELGEERRVSLEQQYWLYQLSRQVDELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEF 1763
Query: 5200 ARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEA 5379
A +T G ER+A N D LI GHT A T+A WKD LNEAW LLELM TRAQ+L A
Sbjct: 1764 ASETGTAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAELLELMGTRAQLLAA 1823
Query: 5380 SRLLHKFYHDCRDCLSRIMEKTHAMPDDLG--RDSSSVGALSRKHQNYLKDIAAIGEQVA 5553
SR LHKF+ D R+ +I EK +P S ++ R + + D+ + QV
Sbjct: 1824 SRELHKFFSDARELQGQIEEKRRRLPRLTAPPEPRPSASSMQRTLRAFEHDLQLLVSQVR 1883
Query: 5554 QIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVR 5733
Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ + T+D +F + R
Sbjct: 1884 QLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLAACEDARLHVSSTADALRFHSQAR 1943
Query: 5734 DLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRK 5913
DLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR C LGR LL K
Sbjct: 1944 DLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELATCQELGRSLLLNK 2003
Query: 5914 HYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLI 6093
+ EI+ +L KL + + E+ +W+ WE+LQ +LEV+QFA++A VA++WL AQEP L
Sbjct: 2004 SAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVVADAWLTAQEPLLQ 2063
Query: 6094 SKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPA 6273
S+E G +++E +LI++HEAF K+A A EERF +L +LTT E + + ++ G
Sbjct: 2064 SRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKLKAEQSKQPPTPLLGRK 2123
Query: 6274 HIGSPS 6291
G P+
Sbjct: 2124 FFGDPT 2129
Score = 91.7 bits (226), Expect = 2e-16
Identities = 63/150 (42%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2389 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGF 2447
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2448 YKDSKGPASGGTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2507
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA A+ E +R QTLP S
Sbjct: 2508 GWLE--AVANSVAEHAEIARWGQTLPTTSS 2535
>gi|13435161|ref|NP_079489.1| spectrin, beta, non-erythrocytic 4 [Homo
sapiens]
gi|11602836|gb|AAG38874.1| beta4sigma1 spectrin [Homo sapiens]
Length = 2559
Score = 1533 bits (3969), Expect = 0.0
Identities = 861/2119 (40%), Positives = 1255/2119 (58%), Gaps = 32/2119 (1%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH+HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF +P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFS----------QPCDPQVICNRVNHVHGCL 621
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 622 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 681
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 682 GAHDLSSTARLLAQHKILQGELGGRRASLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 741
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 742 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 801
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 802 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 861
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 862 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 921
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 922 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 981
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 982 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1035
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1036 LLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1095
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1096 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1155
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1156 GAELGPGLALDEWLPHLELGWHKLLGLWKARRKALVQAHIYQLFLRDLRQALVVLRNQEM 1215
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1216 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1275
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D +
Sbjct: 1276 TRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLH 1335
Query: 3901 SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTE 4080
+++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W ELE TT+
Sbjct: 1336 KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQ 1395
Query: 4081 EKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMI 4260
K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K +E+++
Sbjct: 1396 AKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVE 1455
Query: 4261 KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQ 4440
+ + + P E + + AV E+L RL PL +RR+ L K Q
Sbjct: 1456 EWYREV-GELQAQTAALPLEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ 1514
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
D+DDE W+ ERL LA G L + K Q L EI H P + ++
Sbjct: 1515 VAHDLDDELAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAG 1574
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
L A + +++L+SAW L+EA + R+ L + + Q+ +D E EAW+ E
Sbjct: 1575 ALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGE 1634
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
QEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E P +EQI
Sbjct: 1635 QELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQIS 1694
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS E GQD+
Sbjct: 1695 RRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDF 1754
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD LNEAW L
Sbjct: 1755 EHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAEL 1814
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQN 5514
LELM TRAQ+L ASR LHKF+ D R+ +I EK +P S ++ R +
Sbjct: 1815 LELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRA 1874
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ +
Sbjct: 1875 FEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVS 1934
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
T+D +F + VRDLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR
Sbjct: 1935 STADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELT 1994
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
C LGR LL K + EI+ +L KL T + E+ +W+ WE+LQ +LEV+QFA++A V
Sbjct: 1995 TCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVV 2054
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQ 6234
A++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +L +LTT E + +
Sbjct: 2055 ADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKIKAE 2114
Query: 6235 HREEETAKRRGPAHIGSPS 6291
++ G G P+
Sbjct: 2115 QSKQPPTPLLGRKFFGDPT 2133
Score = 93.6 bits (231), Expect = 6e-17
Identities = 64/150 (42%), Positives = 83/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2393 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGF 2451
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K S HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2452 YKDSKGPASGSTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2511
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA+ A+ E +R QTLP S
Sbjct: 2512 GWLE--AVASSVAEHAEIARWGQTLPTTSS 2539
>gi|40353204|ref|NP_066022.1| spectrin, beta, non-erythrocytic 4 [Homo
sapiens]
gi|33340565|gb|AAQ14860.1| non-erythrocytic beta-spectrin 4 [Homo
sapiens]
Length = 2564
Score = 1531 bits (3965), Expect = 0.0
Identities = 860/2119 (40%), Positives = 1254/2119 (58%), Gaps = 32/2119 (1%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH+HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF GY+P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFSQL-----QGYQPCDPQVICNRVNHVHGCL 626
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 627 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 686
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 687 GAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 746
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 747 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 806
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 807 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 866
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 867 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 926
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 927 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 986
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 987 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1040
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1041 LLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1100
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1101 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1160
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W+ R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1161 GAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQEM 1220
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1221 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1280
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D +
Sbjct: 1281 TRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLH 1340
Query: 3901 SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTE 4080
+++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W ELE TT+
Sbjct: 1341 KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQ 1400
Query: 4081 EKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMI 4260
K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K +E+++
Sbjct: 1401 AKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVE 1460
Query: 4261 KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQ 4440
+ + + P E + + AV E+L RL PL +RR+ L K Q
Sbjct: 1461 EWYREV-GELQAQTAALPLEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ 1519
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
D W+ ERL LA G L + K Q L EI H P + ++
Sbjct: 1520 VAHDWTTSWAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAG 1579
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
L A + +++L+SAW L+EA + R+ L + + Q+ +D E EAW+ E
Sbjct: 1580 ALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGE 1639
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
QEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E P +EQI
Sbjct: 1640 QELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQIS 1699
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS E GQD+
Sbjct: 1700 RRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDF 1759
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD LNEAW L
Sbjct: 1760 EHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAEL 1819
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQN 5514
LELM TRAQ+L ASR LHKF+ D R+ +I EK +P S ++ R +
Sbjct: 1820 LELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRA 1879
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ +
Sbjct: 1880 FEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVS 1939
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
T+D +F + VRDLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR
Sbjct: 1940 STADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELT 1999
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
C LGR LL K + EI+ +L KL T + E+ +W+ WE+LQ +LEV+QFA++A V
Sbjct: 2000 TCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVV 2059
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQ 6234
A++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +L +LTT E + +
Sbjct: 2060 ADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTTIEKIKAE 2119
Query: 6235 HREEETAKRRGPAHIGSPS 6291
++ G G P+
Sbjct: 2120 QSKQPPTPLLGRKFFGDPT 2138
Score = 93.6 bits (231), Expect = 6e-17
Identities = 64/150 (42%), Positives = 83/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2398 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVSLYCVLSKGELGF 2456
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K S HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2457 YKDSKGPASGSTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2516
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA+ A+ E +R QTLP S
Sbjct: 2517 GWLE--AVASSVAEHAEIARWGQTLPTTSS 2544
>gi|11602890|gb|AAF93173.1| betaIV spectrin isoform sigma4 [Homo
sapiens]
Length = 2149
Score = 1528 bits (3956), Expect = 0.0
Identities = 865/2135 (40%), Positives = 1257/2135 (58%), Gaps = 32/2135 (1%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHXHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF +P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFS----------QPCDPQVICNRVNHVHGCL 621
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 622 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 681
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 682 GAHDLSSTARLLAQHKILQGELGGRRASLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 741
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 742 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 801
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 802 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 861
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 862 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 921
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 922 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 981
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 982 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1035
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1036 LLEEAALLAERFPAQAAXLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1095
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1096 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1155
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1156 GAELGPGLALDEWLPHLELGWHKLLGLWKARRKALVQAHIYQLFLRDLRQALVVLRNQEM 1215
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1216 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1275
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D +
Sbjct: 1276 TRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLH 1335
Query: 3901 SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTE 4080
+++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W ELE TT+
Sbjct: 1336 KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQ 1395
Query: 4081 EKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMI 4260
K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K +E+++
Sbjct: 1396 AKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVE 1455
Query: 4261 KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQ 4440
+ + + P E + + AV E+L RL PL +RR+ L K Q
Sbjct: 1456 EWYREV-GELQAQTAALPLEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ 1514
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
D+DDE W+ ERL LA G L + K Q L EI H P + ++
Sbjct: 1515 VAHDLDDELAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAG 1574
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
L A + +++L+SAW L+EA + R+ L + + Q+ +D E EAW+ E
Sbjct: 1575 ALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGE 1634
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
QEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E P +EQI
Sbjct: 1635 QELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQIS 1694
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS E GQD+
Sbjct: 1695 RRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDF 1754
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD LNEAW L
Sbjct: 1755 EHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAEL 1814
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQN 5514
LELM TRAQ+L ASR LHKF+ D R+ +I EK +P S ++ R +
Sbjct: 1815 LELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRA 1874
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ +
Sbjct: 1875 FEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVS 1934
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
T+D +F + VRDLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++AR
Sbjct: 1935 STADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELEARVPELT 1994
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
C LGR LL K + EI+ +L KL T + E+ +W+ WE+LQ +LEV+QFA++A V
Sbjct: 1995 TCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQFAQEAVV 2054
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQ 6234
A++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +L +LTT +
Sbjct: 2055 ADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTT---PRRE 2111
Query: 6235 HREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDG 6339
+ + H PS P A A+ DG
Sbjct: 2112 DHLNPGVQDQPWQHTEKPSLPKPKANKEKTARRDG 2146
>gi|34855389|ref|XP_218364.2| similar to betaIV-spectrin sigma1
[Rattus norvegicus]
Length = 2588
Score = 1417 bits (3668), Expect = 0.0
Identities = 826/2132 (38%), Positives = 1221/2132 (56%), Gaps = 54/2132 (2%)
Frame = +1
Query: 58 NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLA 237
N++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY D+RDG +L RLL
Sbjct: 56 NAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYADLRDGFVLTRLLE 115
Query: 238 VLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTI 417
VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGL+WTI
Sbjct: 116 VLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHRLTLGLVWTI 175
Query: 418 ILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIH 597
ILRFQ+ + ++ +R C + +V+ S +
Sbjct: 176 ILRFQMWLWNGQISNVDPSRYVDTV----CTRAPMRHMDVHFARRSHGFTQSGTM----- 226
Query: 598 KHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTY 777
PDLVD L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEKSIITYVV++
Sbjct: 227 ---PDLVDLSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEKSIITYVVSF 283
Query: 778 YHYFNKLKQDNIQGKRIGK-------------------------VINELMENDKMINRYE 882
YHYF+K+K ++GKRIGK V+++++E DK+I RYE
Sbjct: 284 YHYFSKMKALAVEGKRIGKTPHTVDLEISPERNETDSPFFVLGQVLDQVLEVDKIIERYE 343
Query: 883 TLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFT 1062
L+++LL WI+ + L++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF+
Sbjct: 344 ELAAELLAWIHRTVDLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFS 403
Query: 1063 LQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFN 1242
+QS +RA+N+R FVPREG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+
Sbjct: 404 IQSKLRAHNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFD 463
Query: 1243 RKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXX 1422
K MRE+WL ENQRLVSQDNFG +L +VEAA KKHEAIE DI AYEER
Sbjct: 464 HKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQAL 523
Query: 1423 XXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIK 1602
Y+D ++ ++++V ARR RLE ++A+QK+F ++
Sbjct: 524 AAEGYYDARRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQ 583
Query: 1603 SRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPV 1782
++LLS + G HL++ +DLLQKH LLE DI ERV A A RF GY+P
Sbjct: 584 TQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQL-----QGYQPC 638
Query: 1783 EPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSST 1962
+P I R + + EL + AA R+ LE ++ L ++ E E +++E++L +T
Sbjct: 639 DPQVICNRVNHVHGCLSELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAT 698
Query: 1963 D----------TGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQ---DESIPG 2103
D+ + + LLA+HK + L L + G+EL PG
Sbjct: 699 SGSGGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRRGEELAAAGGSVGPG 758
Query: 2104 SD-----NIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRV 2268
++ + R A R +L+E +A R+ RL +QF D D + +L D R+
Sbjct: 759 AEPLHLAGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRL 818
Query: 2269 MSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQR 2439
++ D G DE + + L ++H + E++ + L + +L + P ++ R
Sbjct: 819 AAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVGGLRRQLATLGGASGAGPLVVALQVR 878
Query: 2440 LDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGK-LLATLVPGRDIE 2616
+ + AE+ ++ LR+Q L DAL++Y+++ + + E WI EK + LLA VP ++
Sbjct: 879 VVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLAMRVPD-SLD 937
Query: 2617 EVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRD 2796
+VE+++HRF++L+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ +
Sbjct: 938 DVEVVQHRFESLDQEMNSLMGRVLDVNQTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVE 997
Query: 2797 MVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMME 2976
+V+Q++ E+ +E ++ E + +K R +E + LQ RLS +E
Sbjct: 998 LVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLE 1051
Query: 2977 RDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAG 3156
L A++ + +L +EA + P +A + + + + W L + + AG
Sbjct: 1052 AALQALEPRQAALLEEAALLAERFPAQATRLHQGAEELGAEWGALAGAAQACGEAVAAAG 1111
Query: 3157 DLQRFLRDLDHFQAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKK 3330
LQRFLRDLD F WL Q + E P+SL EA+ LL +HAA++EE+D EDY +
Sbjct: 1112 RLQRFLRDLDTFLDWLVRAQEAAGAVEGPLPRSLEEADGLLARHAALKEEVDQREEDYAR 1171
Query: 3331 MRAMGDRVTQD---QTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRD 3501
+ A + + + P + L + L L+ GW +L +W+ R+ L Q Q+FLRD
Sbjct: 1172 IVAASEALLASDGAELGPG-LALDEWLPHLEVGWHKLLGLWEERREALVQAHVYQLFLRD 1230
Query: 3502 AKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQ 3681
QA +L QE L+ ++P ++E E +KRH+DF+TTM+ N +K++ + L +
Sbjct: 1231 LCQALAVLRNQEVALSGAELPCTVESVEEAMKRHRDFLTTMELNQQKMQVAVQAAEGLLR 1290
Query: 3682 DGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIR 3861
G+ ++ + + E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+
Sbjct: 1291 QGNAYGEQAQEAVARLLEKSQENQLRAQQWMQKLLDQLVLQHFLRDCHELDGWIHEKMLM 1350
Query: 3862 AQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEE 4041
A+D T D+ + +++RHQAF +ELA NKE L++++ L +KPE ++ ++ E
Sbjct: 1351 ARDGTREDSHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGE 1410
Query: 4042 LATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNV 4221
+ W ELE TT+ K ++LF+A++ VQS A++ + +E+++ D GDL TVN
Sbjct: 1411 IRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKRLLHMESQLQDVDPGGDLATVNS 1470
Query: 4222 AMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDD 4401
++K +E+++ + + + + E + + AV E+L RL PL +
Sbjct: 1471 QLKKLQSMESQVEEWCREVGELQAQTAALPLEQASK-ELVGERQSAVGERLVRLLEPLQE 1529
Query: 4402 RRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDN 4581
RR+ L K Q D+DDE W+ ERL LA G L + K Q L EI
Sbjct: 1530 RRRLLLASKELHQVAHDLDDELAWVQERLPLAMLTERGTGLQAVQQHIKKNQGLRREIQA 1589
Query: 4582 HEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQF 4761
H P + ++ L A + ++L+SAW L+EA + R+ L + + Q+
Sbjct: 1590 HGPRLEEVLERAGVLASLRSPEAEAVRRGQEQLQSAWTGLREATERRQQTLDAAFQVEQY 1649
Query: 4762 LYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHK 4941
+D E EAW+ EQEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ +
Sbjct: 1650 YFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRA 1709
Query: 4942 FVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADK 5121
+E P +EQI RQ+Q+++LY L++ Y L R++D+L WIA+K
Sbjct: 1710 LLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVSLEQQYWLYQLSRQVDELEHWIAEK 1769
Query: 5122 EVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIA 5301
EVVAGS E GQD+EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A
Sbjct: 1770 EVVAGSPELGQDFEHVSVLQEKFSEFASETGTAGRERLAAVNQMVDELIECGHTAAATMA 1829
Query: 5302 LWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLG--RD 5475
WKD LNEAW LLELM TRAQ+L ASR LHKF+ D R+ +I EK +P
Sbjct: 1830 EWKDGLNEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTAPPEP 1889
Query: 5476 SSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRH 5655
S ++ R + + D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+
Sbjct: 1890 RPSASSMQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKE 1949
Query: 5656 LRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQS 5835
L C+ + T+D +F + RDLL WMD + ++ + ++P+DVS VE+LMN HQ
Sbjct: 1950 LLAACEDARLHVSSTADALRFHSQARDLLSWMDGIAGQIGAADKPRDVSSVEVLMNYHQG 2009
Query: 5836 LKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQL 6015
LK E++AR AC LGR LL K + EI+ +L KL + + E+ +W+ WE+LQ
Sbjct: 2010 LKTELEARVPELTACQELGRSLLLNKSAMADEIQAQLDKLGSRKEEVSEKWDRHWEWLQQ 2069
Query: 6016 ILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLA 6195
+LEV+QFA++A VA++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +
Sbjct: 2070 MLEVHQFAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSS 2129
Query: 6196 LEKLTTFELKETQHREEETAKRRGPAHIGSPS 6291
L +LTT E + + ++ G G P+
Sbjct: 2130 LRRLTTIEKLKAEQSKQPPTPLLGRKFFGDPT 2161
Score = 91.7 bits (226), Expect = 2e-16
Identities = 63/150 (42%), Positives = 81/150 (54%), Gaps = 3/150 (2%)
Frame = +1
Query: 6289 SRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
SRS PA S A EG L+RK ++ +RK++NRSW LY VL + EL F
Sbjct: 2422 SRSAPAQGGSAPAPPPPPTHTVQHEGFLLRKRELDA-NRKSSNRSWVNLYCVLSKGELGF 2480
Query: 6469 YKDPKH-RDESVHG-EPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQ 6642
YKD K HG EP ++L + VASDY+KKK+V L+ G+E+L Q EE+M
Sbjct: 2481 YKDSKGPASGGTHGGEPLLSLHKATSEVASDYKKKKHVFKLQTQDGSEFLLQAKDEEEMN 2540
Query: 6643 RWLTELQVATGQAQLEEASR-SQTLPAEGS 6729
WL VA A+ E +R QTLP S
Sbjct: 2541 GWLE--AVANSVAEHAEIARWGQTLPTTSS 2568
>gi|33340563|gb|AAQ14859.1| beta spectrin IV [Homo sapiens]
Length = 2002
Score = 1387 bits (3591), Expect = 0.0
Identities = 785/1953 (40%), Positives = 1147/1953 (58%), Gaps = 32/1953 (1%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH+HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF GY+P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFSQL-----QGYQPCDPQVICNRVNHVHGCL 626
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 627 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 686
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 687 GAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 746
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 747 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 806
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 807 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 866
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 867 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 926
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 927 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 986
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 987 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1040
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1041 LLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1100
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1101 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1160
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W+ R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1161 GAELGPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQEM 1220
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1221 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1280
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T D +
Sbjct: 1281 TRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLH 1340
Query: 3901 SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTE 4080
+++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W ELE TT+
Sbjct: 1341 KRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWAELESTTQ 1400
Query: 4081 EKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMI 4260
K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K +E+++
Sbjct: 1401 AKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVE 1460
Query: 4261 KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQ 4440
+ + + P E + + AV E+L RL PL +RR+ L K Q
Sbjct: 1461 EWYREV-GELQAQTAALPLEPASKELVGERQNAVGERLVRLLEPLQERRRLLLASKELHQ 1519
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
D W+ ERL LA G L + K Q L EI H P + ++
Sbjct: 1520 VAHDWTTSWAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAG 1579
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
L A + +++L+SAW L+EA + R+ L + + Q+ +D E EAW+ E
Sbjct: 1580 ALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGE 1639
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
QEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E P +EQI
Sbjct: 1640 QELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGHPDSEQIS 1699
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS E GQD+
Sbjct: 1700 RRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGSPELGQDF 1759
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD LNEAW L
Sbjct: 1760 EHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGLNEAWAEL 1819
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGALSRKHQN 5514
LELM TRAQ+L ASR LHKF+ D R+ +I EK +P S ++ R +
Sbjct: 1820 LELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASSMQRTLRA 1879
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+ D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+ +
Sbjct: 1880 FEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACEDARLHVS 1939
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPK 5793
T+D +F + VRDLL WMD + ++ + ++P+
Sbjct: 1940 STADALRFHSQVRDLLSWMDGIASQIGAADKPR 1972
Score = 235 bits (600), Expect = 1e-59
Identities = 275/1393 (19%), Positives = 568/1393 (40%), Gaps = 55/1393 (3%)
Frame = +1
Query: 2239 DRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEARE 2418
+ +L + R++S ++ G + V+ +KKH+ + ++ +++ ++ + A++L E
Sbjct: 442 ESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEG-- 499
Query: 2419 HPDIRQ---RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLA 2589
+ DIR+ + D+ L+Q A L L R+ RL L+L K++ + + W++E L
Sbjct: 500 YYDIRRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLL 559
Query: 2590 TLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLA---RQLLNVEHPNSDDILHRQ 2760
+ G+ + E + + + LE D+ Q +V +N A QL + + I +R
Sbjct: 560 SRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQLQGYQPCDPQVICNRV 619
Query: 2761 NKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDAL------ 2922
N ++ A+L++ ++R ELE + L + +E +W DK R+LE +
Sbjct: 620 NHVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAA 679
Query: 2923 --------TNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIRED 3078
+DLS +L + +++ +LG +A L ++A E A+
Sbjct: 680 GAAGTAGGAHDLSSTARLLAQHKILQGELGGRRALL----QQALRCGEELVAAGGAVGPG 735
Query: 3079 IKRIHQV------------WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQ 3222
+H V W L + E +L EA L +F DLD WL R
Sbjct: 736 ADTVHLVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRL 795
Query: 3223 VASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRA-MGDRVTQDQTDPQYMFLRQR 3399
A+ + A + +L QH A+ E++ + +R + P + L+ R
Sbjct: 796 AAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVR 855
Query: 3400 LAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQ 3579
+ ++ + E+ + R+ L L + + E+ + ++E +L +P SL+
Sbjct: 856 VVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDD 915
Query: 3580 AENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREK 3759
E R + M++ ++ V +L + GH ++D++ +++ R E
Sbjct: 916 VEVVQHRFESLDQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVEL 975
Query: 3760 AQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSEL 3939
++ +++ L ++ + + E+R + EK RA + R + + ++ L
Sbjct: 976 VEQRKEEMSAVLLVENHVLEVAEVRAQVREKR-RAVESAPRAGGALQWRL---SGLEAAL 1031
Query: 3940 AANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQ 4119
A + R L A L + P + EEL +W L + G+ + A R Q
Sbjct: 1032 QALEPRQAALLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQ 1091
Query: 4120 LYVQSIADMKEWATQLENEMTREDQP--GDLTTVNVAMQKQHLIETEMIKKAQHIDXXXX 4293
++ + +W + + + P L + + + ++ E+ ++ +
Sbjct: 1092 RFLHDLDAFLDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVA 1151
Query: 4294 XXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPL-------DDRRKALERKKAAFQFGRD 4452
EL LA+ E L L+ + RR+AL + F RD
Sbjct: 1152 ASEALLAADGAEL----GPGLALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRD 1207
Query: 4453 VDDEKLWI-SERLVLAKAQNLG--ESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQE 4623
+ + + ++ + L+ A+ G ES+ + + ++ L + E+ + + G
Sbjct: 1208 LRQALVVLRNQEMALSGAELPGTVESVEEALKQHRDF-LTTMELSQQKMQVAVQAAEG-- 1264
Query: 4624 LIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQ 4803
L+ +G+ G ++ + L QE + + L + + FL DC E + W+ E+
Sbjct: 1265 LLRQGNIYGEQAQEAVTRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEK 1324
Query: 4804 ELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQV 4983
L M +D +D + +H+ +++ + + + + + + ++EK L ++
Sbjct: 1325 ML-MARDGTREDNHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRK 1383
Query: 4984 RQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYE 5163
+ +I + +A L+ L + +L + + E + G D
Sbjct: 1384 KLGEIRQCWAELESTTQAKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLA 1443
Query: 5164 HV-------QMLQERFQQFARDTENIGSERVA-NANDGCDTLIGHGHTDAPTIALWKDSL 5319
V Q ++ + +++ R+ + ++ A L+G ++++
Sbjct: 1444 TVNSQLKKLQSMESQVEEWYREVGELQAQTAALPLEPASKELVGER----------QNAV 1493
Query: 5320 NEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTH-AMPDDLGRDSSSVGAL 5496
E LLE + R ++L AS+ LH+ HD + + E+ AM + G +V
Sbjct: 1494 GERLVRLLEPLQERRRLLLASKELHQVAHDWTTSWAWVQERLPLAMQTERGNGLQAVQQH 1553
Query: 5497 SRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDA 5676
+K+Q ++I A G ++ ++ A L +A + ++ AW LR +
Sbjct: 1554 IKKNQGLRREIQAHGPRLEEVLERAGALAS-LRSPEAEAVRRGLEQLQSAWAGLREAAER 1612
Query: 5677 RTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDA 5856
R L + ++ V ++ W+ E + M S+++ KD L+ H L+ ++
Sbjct: 1613 RQQVLDAAFQVEQYYFDVAEVEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVEN 1672
Query: 5857 REENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
EE+ R LL H S +I ++ ++ + E+R L+ +YQ
Sbjct: 1673 YEESIAQLSRQCRALLEMGHPDSEQISRRQSQVDRLYVALKELGEERRVALEQQYWLYQL 1732
Query: 6037 ARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF-EKSAFAQEERFLALEKLTT 6213
+R + E W+ +E S E G++ E L +K F ++ A ER A+ ++
Sbjct: 1733 SRQVSELEHWIAEKEVVAGSPELGQDFEHVSVLQEKFSEFASETGMAGRERLAAVNQMVD 1792
Query: 6214 FELKETQHREEET 6252
EL E H T
Sbjct: 1793 -ELIECGHTAAAT 1804
Score = 134 bits (336), Expect = 4e-29
Identities = 237/1320 (17%), Positives = 500/1320 (36%), Gaps = 51/1320 (3%)
Frame = +1
Query: 2458 QKAELENLSQLRKQRLIDALSLYKLYSDADSV----ESWIDEKGKLLATLVPGRDIEEVE 2625
+KAE E + LR + LI L L D ESW++E +L++ G ++ VE
Sbjct: 407 EKAEHEREAALRAE-LIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYELPAVE 465
Query: 2626 IMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVD 2805
+ + +E D+ E +V V +LA+ L + + + +++ + +WA L +V
Sbjct: 466 AAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRDSVLRQWALLTGLVG 525
Query: 2806 QKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDL 2985
+R LE+ L+ + V W+E+ L + + + LQ+ ++E D+
Sbjct: 526 ARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEADDLLQKH-GLLEGDI 584
Query: 2986 GAIQAKLDSLHKEA---DDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAG 3156
A ++++L+ A ++ +P + Q I + +H L ++ A+L+ +
Sbjct: 585 AAQSERVEALNAAALRFSQLQGYQPCDPQVICNRVNHVHGCLAELQEQAARRRAELEASR 644
Query: 3157 DLQRFLRDLDHFQAWLTATQRQV---------------ASEEEPQSLAEAEQLLNQHAAI 3291
L L++L+ ++W +R + + L+ +LL QH +
Sbjct: 645 SLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAGGAHDLSSTARLLAQHKIL 704
Query: 3292 REEIDGYAEDYKK-------MRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDN 3450
+ E+ G ++ + A G V + L +R A + W+ L+
Sbjct: 705 QGELGGRRALLQQALRCGEELVAAGGAVGPGADTVHLVGLAERAASARRRWQRLEEAAAR 764
Query: 3451 RQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDA 3630
R+ L + L F D L A D + ++H+ ++A
Sbjct: 765 RERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEA 824
Query: 3631 NDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK--LKDALSLQ 3804
+ + + L + + R ++ + L++ L+DAL++
Sbjct: 825 HRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDALAVY 884
Query: 3805 QFLSDCDELREWIEEK-----MIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL 3969
+ + WI EK +R D + D + + +F ++ E+ + R+ +
Sbjct: 885 RMFGEVHACELWIGEKEQWLLSMRVPD-SLDDVEVVQHRF---ESLDQEMNSLMGRVLDV 940
Query: 3970 KHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK 4149
H L + + + L ++W+ + + E++ +++ + +V +A+++
Sbjct: 941 NHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVR 1000
Query: 4150 EWATQLENEMTREDQPGD-----LTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXX 4314
+ + + G L+ + A+Q + ++++A +
Sbjct: 1001 AQVREKRRAVESAPRAGGALQWRLSGLEAALQALEPRQAALLEEAALLAERFPAQAARLH 1060
Query: 4315 XHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVL 4494
+EL + L + +A+ +F D+D W+
Sbjct: 1061 QGAEELG----------AEWGALASAAQACGEAVAAAGRLQRFLHDLDAFLDWLVRAQEA 1110
Query: 4495 AKAQN--LGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELID-EGHANGP--AF 4659
A L SL + L L E+D E +I + L+ +G GP A
Sbjct: 1111 AGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAADGAELGPGLAL 1170
Query: 4660 EKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKD 4839
++ + L W +L + R+ L ++ FL D +A + QE+ + E
Sbjct: 1171 DEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALVVLRNQEMALSGAELPGT 1230
Query: 4840 EFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGL 5019
S + +K+H + ++ ++ A + + + EQ Q ++ +
Sbjct: 1231 VESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAVTRLLEKNQEN 1290
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVA--GSQENGQDYEHVQMLQERFQ 5193
Q R+ +L WI +K ++A G++E+ + + F
Sbjct: 1291 QLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTREDNHKLHKRWLRHQAFM 1350
Query: 5194 -QFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRA-Q 5367
+ A++ E + E++ L+ A ++ + + W L +A Q
Sbjct: 1351 AELAQNKEWL--EKIEREGQ---QLMQEKPELAASVRKKLGEIRQCWAELESTTQAKARQ 1405
Query: 5368 ILEASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGE 5544
+ EAS+ + + +++ + D D G D ++V + +K Q+ +
Sbjct: 1406 LFEASKA-DQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQSMESQVEEWYR 1464
Query: 5545 QVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMN 5724
+V +++ A L A + +G R++ V + L R L+ + +L + +
Sbjct: 1465 EVGELQAQTAALPLEPASKEL--VGERQNAVGERLVRLLEPLQERRRLLLASKELHQVAH 1522
Query: 5725 MVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLL 5904
W+ E ER + V+ + +Q L+ EI A + L
Sbjct: 1523 DWTTSWAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLEEVLERAGALA 1582
Query: 5905 NRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEP 6084
+ + + + + L +L + A + E R + L +V Q+ D A E+WL QE
Sbjct: 1583 SLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAEVEAWLGEQEL 1642
Query: 6085 YLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRR 6264
++S++ G++ + T++L+KKH E+ EE L + L E H + E RR
Sbjct: 1643 LMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCR-ALLEMGHPDSEQISRR 1701
Score = 40.8 bits (94), Expect = 0.46
Identities = 44/181 (24%), Positives = 80/181 (43%), Gaps = 16/181 (8%)
Frame = +1
Query: 5713 KFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNN---HQSLKAEIDAREE-NFNAC 5880
++ + +LL W+ +++Q+ +SGV+ + + +L+ + +E+ N
Sbjct: 313 RYEELAAELLAWIHRTVGLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVL 372
Query: 5881 ISLGRDLL---NRKHYASSE------IEK---KLIKLTTERAEMMRRWEDRWEYLQLILE 6024
+ + L NR+ + E I+K +L K ER +R R E L+L+ +
Sbjct: 373 LFSIQSKLRACNRRLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQ 432
Query: 6025 VYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
+F A+ ESWL + + +G L +KKHEA E A EER + +
Sbjct: 433 --RFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAE 490
Query: 6205 L 6207
L
Sbjct: 491 L 491
>gi|50510447|dbj|BAD32209.1| mKIAA0302 protein [Mus musculus]
Length = 1972
Score = 1334 bits (3452), Expect = 0.0
Identities = 723/1728 (41%), Positives = 1051/1728 (59%), Gaps = 4/1728 (0%)
Frame = +1
Query: 1198 LIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFA 1377
LIRQEKLEQLAARF+RKA MRETWL+ENQRLVSQDNFG +L++VEAA +KHEAIETDI A
Sbjct: 1 LIRQEKLEQLAARFDRKAAMRETWLSENQRLVSQDNFGLELAAVEAAVRKHEAIETDIVA 60
Query: 1378 YEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKI 1557
Y R +YHD +I R+ NV ARR RL L++ +QK+
Sbjct: 61 YSGRVQAVDAVAAELAAEHYHDIKRIAARQNNVARLWDFLRQMVAARRERLLLNLELQKV 120
Query: 1558 FHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQR 1737
F +K RL S+DLG HL VEDLLQ H L+E+DI + ERV A A R
Sbjct: 121 FQDLLYLMDWMAEMKGRLQSQDLGKHLAGVEDLLQLHELVEADIAVQAERVRAVSASALR 180
Query: 1738 FRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAE 1917
F +P G Y+P +P + ER L++ Y+ L +LAA R+ RLE+++RL +F W+V E
Sbjct: 181 FCDP----GKEYRPCDPQLVSERVATLEQSYEALCELAATRRARLEESRRLWRFLWEVGE 236
Query: 1918 LEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESI 2097
E ++EQ+ +L+S DTGRD+ V LL KH + L G++L E
Sbjct: 237 AEAWVREQQHLLASADTGRDLTGVLRLLNKHAALRGEMSGRLGPLKLTLEQGQQLVAEGH 296
Query: 2098 PGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSS 2277
PG++ R AE++ +L+ L+ R ++LA YQF DA+D++ +L D LR++SS
Sbjct: 297 PGANQASTRAAELQAQWERLEALAEERAQQLAQAASLYQFQADANDMEAWLVDALRLVSS 356
Query: 2278 EDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLK 2457
+VG DE + Q L ++H + +E++ + L +A +LP P+++ R+ T +
Sbjct: 357 PEVGHDEFSTQALARQHRALEEEIRAHRPTLDALREQAAALPPALSHTPEVQGRVPTLEQ 416
Query: 2458 QKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKH 2637
EL+ + R + L AL+ Y + S+A + W++EK + L L +E++E+++
Sbjct: 417 HYEELQTRAGERARALEAALAFYTMLSEAGACGLWVEEKEQWLNGLALPERLEDLEVVQQ 476
Query: 2638 RFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRN 2817
RF+TLE +M A+VT VND+A QLL P D I+ Q +LN RW Q R + D K+
Sbjct: 477 RFETLEPEMNALAARVTAVNDIAEQLLKASPPGKDRIIGTQEQLNQRWQQFRSLADGKKA 536
Query: 2818 ELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQ 2997
L A ++ + ++C ET W+ +KT+V+E + L NDL+GV+ LQR+L+ ERDL AI
Sbjct: 537 ALTSALSIQNYHLECTETQAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAIS 596
Query: 2998 AKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLR 3177
A++ L +EA+ + P +A AI + + W+ L +R E L EA LQ FLR
Sbjct: 597 ARVGELTQEANALAAGHPAQAPAINTRLGEVQAGWEDLRATMRRREESLGEARRLQDFLR 656
Query: 3178 DLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVT 3357
LD FQAWL TQ VASEE P +L EAE LL QHAA+R E++ +Y ++R +G+ VT
Sbjct: 657 SLDDFQAWLGRTQTAVASEEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVT 716
Query: 3358 QDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQE 3537
+DQ DPQ +FLRQRL L GWEEL RMW++RQ L+Q Q FLRDA+QAE +LS QE
Sbjct: 717 RDQADPQCLFLRQRLEALGTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQE 776
Query: 3538 NYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKK 3717
L+ ++P +L+ A+ +K+ +DF++TMDAN E+IR + G QL G+ A+KI +K
Sbjct: 777 YVLSHTEMPGTLQAADAAIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGNIHAEKIQEK 836
Query: 3718 ARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTI 3897
A +I++R N+E Q++L +L+D Q FL DC EL+ WI+EKM+ AQD +Y +A+ +
Sbjct: 837 ADSIEKRHRKNQEAVQQLLGRLRDNREQQHFLQDCQELKLWIDEKMLTAQDVSYDEARNL 896
Query: 3898 TSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTT 4077
+K+ +HQAF +ELAANK+ LD++ L +KPE + ++E+L +WDELE TT
Sbjct: 897 HTKWQKHQAFMAELAANKDWLDKVDKEGRELTLEKPELKVVVSEKLEDLHRRWDELETTT 956
Query: 4078 EEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEM 4257
+ K + LFDANR +L+ QS + ++ W L+ ++ +D DLT+VN+ ++KQ ++E EM
Sbjct: 957 QAKARSLFDANRAELFAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREM 1016
Query: 4258 IKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAF 4437
+ + ++ E + R AV+E+ + L P+ +R + L +
Sbjct: 1017 AVREKEVEAIQAQAQALAQEDQSAGEVERTSR-AVEEKFRALCQPMKERCRRLHASREQH 1075
Query: 4438 QFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNG 4617
QF RDV+DE LW++ERL +A + G+ LP L K Q L EI HEP I +
Sbjct: 1076 QFHRDVEDEILWVTERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLKERQ 1135
Query: 4618 QELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMS 4797
+ L A GP ++ EL+ W+ L ++ R L E+ +A QF D EAEAWM
Sbjct: 1136 RTL--GTAAAGP----ELAELQEMWKRLSHELELRGKRLEEALRAQQFYRDAAEAEAWMG 1189
Query: 4798 EQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQI 4977
EQEL+MM E+ KDE S + ++KKH+ L+ + +A TI+ LA + ++ + P + ++
Sbjct: 1190 EQELHMMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRL 1249
Query: 4978 QVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQD 5157
+RQAQ++KLYA L++ L RE+DDL QWI ++EVVA S E GQD
Sbjct: 1250 TIRQAQVDKLYASLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQD 1309
Query: 5158 YEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWEN 5337
YEHV ML+++F++F++DT IG ERV +AN + LI GH T+A WKDSLNEAW +
Sbjct: 1310 YEHVTMLRDKFREFSKDTSTIGQERVDSANALANGLIAGGHAARATVAEWKDSLNEAWAD 1369
Query: 5338 LLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNY 5517
LLEL+DTR Q+L A+ L +F H R L+R+ K +PD GRD ++ AL R+H Y
Sbjct: 1370 LLELLDTRGQVLAAAYELQRFLHGARQALARVQHKQQQLPDGTGRDLNAAEALQRRHCAY 1429
Query: 5518 LKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMD 5697
DI A+ QV Q++ D L+ YAGDKA +IG V +AW L+G AR L+D
Sbjct: 1430 EHDIQALSTQVQQVQDDGQRLQKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAARRQLLLD 1489
Query: 5698 TSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNA 5877
T+D F+F VR+L+LWMD + +M++QERP+DVS +L++ N Q +KAEI+AR + F++
Sbjct: 1490 TTDKFRFFKAVRELMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIKAEIEARADRFSS 1549
Query: 5878 CISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVA 6057
CI +G++LL R HYA+ EI +KL +L + R E +W+++ ++LQL+LEV F RDA +A
Sbjct: 1550 CIDMGQELLARSHYAAEEISEKLSQLQSRRQETADKWQEKMDWLQLVLEVLVFGRDAGMA 1609
Query: 6058 ESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQH 6237
E+WL +QEP + S E G ++E LIK+HEAF+KSA A EERF ALEKLT E +E +
Sbjct: 1610 EAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQKSAVAWEERFSALEKLTALEERENER 1669
Query: 6238 ---REEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGE-AFEGT 6369
REEE +++ P S P A G+ DG + + A++GT
Sbjct: 1670 KRKREEEERRKQ-------PPTSEPMASQPEGSLVDGQRVPDTAWDGT 1710
Score = 217 bits (552), Expect = 4e-54
Identities = 286/1481 (19%), Positives = 567/1481 (37%), Gaps = 29/1481 (1%)
Frame = +1
Query: 850 MENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFD 1029
+E + + R+ + W+ + LL +L GV R L + R +
Sbjct: 221 LEESRRLWRFLWEVGEAEAWVREQQHLLASADTGRDLTGVLRLLNKHAALRGEMS----- 275
Query: 1030 EKGELEVLLFTLQSAMRANNQ-RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIR 1206
G L L TL+ + + P + A++ W+ LE ER ++L +
Sbjct: 276 --GRLGPLKLTLEQGQQLVAEGHPGANQASTRAAELQAQWERLEALAEERA----QQLAQ 329
Query: 1207 QEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEE 1386
L Q F A E WL + RLVS G+D S +A ++H A+E +I A+
Sbjct: 330 AASLYQ----FQADANDMEAWLVDALRLVSSPEVGHDEFSTQALARQHRALEEEIRAHRP 385
Query: 1387 RXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHX 1566
H ++ R + R LE ++A +
Sbjct: 386 TLDALREQAAALPPALSH-TPEVQGRVPTLEQHYEELQTRAGERARALEAALAFYTMLSE 444
Query: 1567 XXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVN--NSIAQAQRF 1740
+ L L L D+E + Q+ LE ++N + RV N IA+
Sbjct: 445 AGACGLWVEEKEQWLNGLALPERLEDLEVVQQRFETLEPEMNALAARVTAVNDIAEQLLK 504
Query: 1741 RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAEL 1920
+P G D I + L +R+++ LA +K L + + + E
Sbjct: 505 ASPPGKD----------RIIGTQEQLNQRWQQFRSLADGKKAALTSALSIQNYHLECTET 554
Query: 1921 EHGIKEQEQVLSSTD-TGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESI 2097
+ ++E+ +V+ ST G D+ V L K E +L + + L L
Sbjct: 555 QAWMREKTKVIESTQGLGNDLAGVLALQRKLAGTERDLEAISARVGELTQEANALAAGHP 614
Query: 2098 PGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSS 2277
+ I RL E++ L+ R+E L F DD +L T ++S
Sbjct: 615 AQAPAINTRLGEVQAGWEDLRATMRRREESLGEARRLQDFLRSLDDFQAWLGRTQTAVAS 674
Query: 2278 EDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP--DIRQRLDTT 2451
E+ + LL +H + E++ L E + ++ + +RQRL+
Sbjct: 675 EEGPATLPEAEALLAQHAALRGEVERAQSEYSRLRTLGEEVTRDQADPQCLFLRQRLEAL 734
Query: 2452 LKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLA-TLVPGRDIEEVEI 2628
EL + + R+ RL A DA E + + +L+ T +PG ++ +
Sbjct: 735 GTGWEELGRMWESRQGRLAQAHGFQGFLRDARQAEGVLSSQEYVLSHTEMPG-TLQAADA 793
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
+ + M ++ + + RQL++ + +++ I + + + R + ++ V Q
Sbjct: 794 AIKKLEDFMSTMDANGERIRGLLEAGRQLVSKGNIHAEKIQEKADSIEKRHRKNQEAVQQ 853
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
L + F DCQE WI++K +L D ++ + ++ +L
Sbjct: 854 LLGRLRDNREQQHFLQDCQELKLWIDEK--MLTAQDVSYDEARNLHTKWQKHQAFMAELA 911
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
A + LD + KE ++ E+P+ + E ++ +H+ WD L + L +A +
Sbjct: 912 ANKDWLDKVDKEGRELTLEKPELKVVVSEKLEDLHRRWDELETTTQAKARSLFDANRAEL 971
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
F + ++WL + Q Q+ S++ + L LL + + E+ ++ + ++A
Sbjct: 972 FAQSCSALESWLESLQAQLHSDDYGKDLTSVNILLKKQQMLEREMAVREKEVEAIQAQAQ 1031
Query: 3349 RVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLS 3528
+ Q+ D + + ++E + L + R L F RD + + ++
Sbjct: 1032 ALAQE--DQSAGEVERTSRAVEEKFRALCQPMKERCRRLHASREQHQFHRDVEDEILWVT 1089
Query: 3529 QQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKI-------RAVG--MFGDQLCQ 3681
++ + + + L + +K++Q + ++ +I R +G G +L +
Sbjct: 1090 ERLPMASSLEHGKDLPSVQLLMKKNQTLQKEIQGHEPRIADLKERQRTLGTAAAGPELAE 1149
Query: 3682 DGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMI 3858
++ K+ + E RG K+L++AL QQF D E W+ E+++
Sbjct: 1150 -----LQEMWKRLSHELELRG----------KRLEEALRAQQFYRDAAEAEAWMGEQELH 1194
Query: 3859 RAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIE 4038
E +D + ++ +HQ + LA + + QL ++ ++ D + + +
Sbjct: 1195 MMGQEKAKDELSAQAEVKKHQVLEQALADYAQTIKQLAASSQDMIDHEHPESTRLTIRQA 1254
Query: 4039 ELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVN 4218
++ + L++ E+ ++L + R + + D+++W + E + D V
Sbjct: 1255 QVDKLYASLKELAGERRERLQEHLRLCQLRRELDDLEQWIQEREVVAASHELGQDYEHVT 1314
Query: 4219 VAMQK--QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAP 4392
+ K + +T I + + +D + + ++ E L
Sbjct: 1315 MLRDKFREFSKDTSTIGQ-ERVDSANALANGLIAGGHAARATVAEWKDSLNEAWADLLEL 1373
Query: 4393 LDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPD--------CHRLQK 4548
LD R + L AA++ R + R LA+ Q+ + LPD LQ+
Sbjct: 1374 LDTRGQVL---AAAYELQRFLH------GARQALARVQHKQQQLPDGTGRDLNAAEALQR 1424
Query: 4549 NLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFE--KKIQELRSAWQELKEAVKDR 4722
++I + Q+ ++GQ L + +A A E + +Q + AW +L+ + R
Sbjct: 1425 RHCAYEHDIQALSTQVQQVQDDGQRL-QKAYAGDKAEEIGRHMQAVAEAWAQLQGSSAAR 1483
Query: 4723 KGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKF 4902
+ L ++ +F E WM L M ER +D S IK + ++++I+
Sbjct: 1484 RQLLLDTTDKFRFFKAVRELMLWMDGINLQMDAQERPRDVSSADLVIKNQQGIKAEIEAR 1543
Query: 4903 ADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALH 5082
AD + + + E+I + +Q++ D
Sbjct: 1544 ADRFSSCIDMGQELLARSHYAAEEISEKLSQLQSRRQETADKWQEKMDWLQLVLEVLVFG 1603
Query: 5083 REIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFAR 5205
R+ W+ +E + S E G + V+ L +R + F +
Sbjct: 1604 RDAGMAEAWLCSQEPLVRSAELGCTVDEVESLIKRHEAFQK 1644
Score = 100 bits (250), Expect = 4e-19
Identities = 62/152 (40%), Positives = 80/152 (51%), Gaps = 4/152 (2%)
Frame = +1
Query: 6238 REEETAKRRGPAHIGSP-SRSTPAAE-TSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKA 6411
R E RGPA P SRS+ AA + + E EG L RK E+ ++KA
Sbjct: 1763 RGERQTLPRGPAPSPMPQSRSSEAAHGATLPTRGPELSAQEQMEGMLCRKQEMEAFNKKA 1822
Query: 6412 ANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSL 6585
ANRSW+ +Y VLR+ L FYKD + V HGE P++L +VA DY+K+K+V L
Sbjct: 1823 ANRSWQNVYCVLRRGSLGFYKDARAASAGVPYHGEVPVSLARAQGSVAFDYRKRKHVFKL 1882
Query: 6586 RLPIGAEYLFQCGSEEDMQRWLTELQVATGQA 6681
L G EYLFQ E +M WL + A A
Sbjct: 1883 GLQDGKEYLFQAKDEAEMSSWLRVVNAAIATA 1914
>gi|476928|pir||A47213 beta-fodrin - human (fragment)
gi|425553|gb|AAB28324.1| beta-fodrin [Homo sapiens]
Length = 1252
Score = 1164 bits (3011), Expect = 0.0
Identities = 605/1257 (48%), Positives = 836/1257 (66%)
Frame = +1
Query: 835 VINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEK 1014
V++ +E +KMI +YE+L+SDLLEWI I +LN R F N+L GVQ+QL FN YRT EK
Sbjct: 1 VLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEK 60
Query: 1015 PPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKE 1194
PPKF EKG LEVLLFT+QS MRANNQ+ ++PREGKLI+DIN+AW+ LEKAEHEREL L+
Sbjct: 61 PPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRN 120
Query: 1195 ELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIF 1374
ELIRQEKLEQLA RF+RKA MRETWL+ENQRLVSQDNFG DL +VEAATKKHEAIETDI
Sbjct: 121 ELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIA 180
Query: 1375 AYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQK 1554
AYEER NYHD +I RK+NV ARR RLE+++ +QK
Sbjct: 181 AYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQK 240
Query: 1555 IFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQ 1734
IF +K +LS+D G HL+ VEDLLQKH L+E+DI I ERV A AQ
Sbjct: 241 IFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQ 300
Query: 1735 RFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVA 1914
+F DG GYKP +P I +R ++ Y+EL LAAER+ RLE+++RL +F+W++A
Sbjct: 301 KFAT----DGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMA 356
Query: 1915 ELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES 2094
E E I+E+E++LSS D G+D+ +V LL+KH+ E+ + + ++ G+++ E
Sbjct: 357 EEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEE 416
Query: 2095 IPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMS 2274
GS+ I R+ IR+ L++LSA RK+RL +QF DADD+D ++ D L+++S
Sbjct: 417 HFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVS 476
Query: 2275 SEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTL 2454
S DVG DE + Q L+KKH DV +E+ N+ + LH +A +LPQE E PD+R RL
Sbjct: 477 SSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHAESPDVRGRLSGIE 536
Query: 2455 KQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMK 2634
++ E+ L++LRKQ L D L+LYK++S+AD+ E WIDEK + L + +E++E+++
Sbjct: 537 ERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQ 596
Query: 2635 HRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKR 2814
HRF++LE +M NQ ++V VN +ARQL++ HP+ +I +Q+KLN RW+Q R++VD+K+
Sbjct: 597 HRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKK 656
Query: 2815 NELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAI 2994
+ L A ++ + ++C ET +WI +KT+V+E + L NDL+GVM LQR+L+ MERDL AI
Sbjct: 657 DALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAI 716
Query: 2995 QAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFL 3174
+AKL L KEA+ +E E P +AQAI + I VW+ + ++ EA L EA LQ+FL
Sbjct: 717 EAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFL 776
Query: 3175 RDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRV 3354
RDLD FQ+WL+ TQ +ASE+ P +L EAE+LL QH I+ EID Y EDY+KMR MG+ V
Sbjct: 777 RDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMV 836
Query: 3355 TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQ 3534
TQ QTD QYMFLRQRL L GW EL +MW+NRQ+LLSQ Q FLRD KQAE L+ Q
Sbjct: 837 TQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQ 896
Query: 3535 ENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHK 3714
E LA ++P +LE AE +K+ +DF+TTMDAN+EKI AV G +L DG+ +D+I +
Sbjct: 897 EYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQE 956
Query: 3715 KARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKT 3894
K +ID+R NRE A E+L +LKD LQ+FL DC EL WI EKM+ AQD +Y +A+
Sbjct: 957 KVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARN 1016
Query: 3895 ITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKT 4074
+ SK+++HQAF +ELA+NKE LD+++ + L +KPE + ++ L W+ LE T
Sbjct: 1017 LHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLEST 1076
Query: 4075 TEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETE 4254
T+ K Q+LFDAN+ +L+ QS AD+ +W LE+++ +D DLT+VN+ ++KQ ++E +
Sbjct: 1077 TQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQ 1136
Query: 4255 MIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAA 4434
M + + I+ + + + RL VQ + L PL++R+ L K
Sbjct: 1137 MEVRKKEIE-ELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEI 1195
Query: 4435 FQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQI 4605
QF RDV+DE LW+ ER+ LA + + G +L L K Q L EI H+P I+ I
Sbjct: 1196 HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDI 1252
Score = 278 bits (712), Expect = 1e-72
Identities = 258/1248 (20%), Positives = 531/1248 (41%), Gaps = 28/1248 (2%)
Frame = +1
Query: 2527 KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLA 2706
K S A + WI++ +L + V+ F+T K K T +L
Sbjct: 14 KYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEK--PPKFTEKGNLE 71
Query: 2707 RQLLNVEHP----NSDDILHRQNKL----NARWAQLRDMVDQK----RNELERAHRLETF 2850
L ++ N + R+ KL N W +L ++ RNEL R +LE
Sbjct: 72 VLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQL 131
Query: 2851 --RIDCQETV--TWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLH 3018
R D + + TW+ + R++ D DL V ++ +E D+ A + ++ ++
Sbjct: 132 ARRFDRKAAMRETWLSENQRLVSQ-DNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVV 190
Query: 3019 KEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQA 3198
A ++E E + + I + ++W+ L + +R +L+ LQ+ +++ +
Sbjct: 191 AVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMD 250
Query: 3199 WLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD----- 3363
W+ + V S++ + L E LL +H + +I AE + + A + D
Sbjct: 251 WMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGYK 310
Query: 3364 QTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENY 3543
DPQ +R R+A ++ ++EL ++ R+ L + L F + + E + ++E
Sbjct: 311 PCDPQV--IRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKI 368
Query: 3544 LAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKAR 3723
L+ DD + L L +H+ F M G+ + + H+ ++KI ++
Sbjct: 369 LSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERII 428
Query: 3724 NIDERRGANREKAQEVLKK-LKDALSLQQFLSDCDELREWIEEKM-IRAQDETYRDAKTI 3897
I E+ AN E+ + KK L++A L QF +D D++ W+ + + I + + D +
Sbjct: 429 YIREQ-WANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYST 487
Query: 3898 TSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTT 4077
S +H+ E+A + LD L A L + E + ++ + ++ E+ + T
Sbjct: 488 QSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHAE-SPDVRGRLSGIEERYKEVAELT 546
Query: 4078 EEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEM 4257
+ Q L D + W + E + P L + V + +E EM
Sbjct: 547 RLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEM 606
Query: 4258 IKKAQHIDXXXXXXXXXXXX-HPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAA 4434
+A + HP E E IKA + + + + + +D ++ AL +
Sbjct: 607 NNQASRVAVVNQIARQLMHSGHPSEKE-IKAQQDKLNTRWSQFRELVDRKKDALLSALSI 665
Query: 4435 FQFGRDVDDEKLWISERL-VLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
+ + ++ K WI E+ V+ Q+LG L LQ+ L + ++ E ++ +
Sbjct: 666 QNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQK 725
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
++L E A ++ E+ W+E+K +K+R+ LGE+ K QFL D + ++W
Sbjct: 726 EAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSW 785
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+S + + ++ + + +HE ++++ID + + + + + ++
Sbjct: 786 LSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDA-- 843
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQ---WIADKEVVAGSQ 5142
Q + +++ L G + +A + + D Q ++ ++E V
Sbjct: 844 QYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHT 903
Query: 5143 ENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLN 5322
E E + ++ + F T + E++ + L+ G+ ++ I DS++
Sbjct: 904 EMPTTLEGAEAAIKKQEDFMT-TMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSID 962
Query: 5323 EAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR 5502
+ E L+ +R L KF DC++ I EK D ++ ++ +
Sbjct: 963 DRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWL 1022
Query: 5503 KHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDART 5682
KHQ ++ ++A+ E + +IE++ +L +A+ + + + + K W L +
Sbjct: 1023 KHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAV-VKEKLTGLHKMWEVLESTTQTKA 1081
Query: 5683 SRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDARE 5862
RL D + F DL W+ ++ ++ S + KD++ V +L+ Q L+ +++ R+
Sbjct: 1082 QRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRK 1141
Query: 5863 ENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFAR 6042
+ S + L+++ ++ E++ K + + T+ E++ +R L E++QF R
Sbjct: 1142 KEIEELQSQAQ-ALSQEGKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNR 1200
Query: 6043 DAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEER 6186
D W+ + P S ++G NL+ LIKK++ +K + R
Sbjct: 1201 DVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPR 1248
Score = 253 bits (646), Expect = 5e-65
Identities = 194/800 (24%), Positives = 357/800 (44%), Gaps = 13/800 (1%)
Frame = +1
Query: 3838 WIEEKM-IRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYH 4014
W+ E + +QD D + + +H+A ++++AA +ER+ + A L + YH
Sbjct: 145 WLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVAREL--EAENYH 202
Query: 4015 GT--IDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTRE 4188
I + + + W+ L + + Q+L Q Q + + +W +++ + +
Sbjct: 203 DIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQ 262
Query: 4189 DQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXX-------HPDELENIKA 4347
D L V +QK L+E ++ +A+ + P + + A
Sbjct: 263 DYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVA 322
Query: 4348 HRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLP 4527
H ++L +L A +RR LE + ++F ++ +E+ WI E+ + + + G+ L
Sbjct: 323 HMEFCYQELCQLAA---ERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLT 379
Query: 4528 DCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKE 4707
RL + +E+ Q G+++I E H ++I +R W L++
Sbjct: 380 SVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQ 439
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
RK L E+ HQF D + +AWM + + + G DE+ST++ +KKH+ +
Sbjct: 440 LSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAE 499
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXX 5067
+I + T+ L +A +E + + ++ R + IE+ Y + +
Sbjct: 500 EIANYRPTLDTLHEQASALPQEHAE-SPDVRGRLSGIEERYKEVAELTRLRKQALQDTLA 558
Query: 5068 XYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAN 5247
Y + E D WI +KE + + + E ++++Q RF+ + N S RVA N
Sbjct: 559 LYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQAS-RVAVVN 617
Query: 5248 DGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLS 5427
L+ GH I +D LN W EL+D + L ++ + ++ +C + S
Sbjct: 618 QIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKS 677
Query: 5428 RIMEKTHAM--PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGD 5601
I EKT + DLG D + V AL RK +D+ AI +++ ++++A +L + D
Sbjct: 678 WIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHP-D 736
Query: 5602 KALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQ 5781
+A I SR +E+ W ++ R + L + S L +F+ + D W+ + + S+
Sbjct: 737 QAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASE 796
Query: 5782 ERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYAS-SEIEKKLIKLT 5958
+ P ++ E L+ H+++K EID EE++ +G + + A + ++L L
Sbjct: 797 DMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALD 856
Query: 5959 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
T E+ + WE+R L QF RD AE++L QE L E LE I
Sbjct: 857 TGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAI 916
Query: 6139 KKHEAFEKSAFAQEERFLAL 6198
KK E F + A EE+ A+
Sbjct: 917 KKQEDFMTTMDANEEKINAV 936
Score = 238 bits (606), Expect = 2e-60
Identities = 208/1128 (18%), Positives = 478/1128 (41%), Gaps = 9/1128 (0%)
Frame = +1
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
R+ +LE R +F A E + E ++++S + G D+ V KH+ E ++
Sbjct: 124 RQEKLEQLAR--RFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAA 181
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
E+ + + +EL+ E+ I R + L EL +R++RL + +
Sbjct: 182 YEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKI 241
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES 2397
F + + ++ + ++ S+D GK V+ LL+KH V ++ + ++ ++A A+
Sbjct: 242 FQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQK 301
Query: 2398 LPQEAREHPD-----IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESW 2562
+ + IR R+ EL L+ R+ RL ++ L+K + + E W
Sbjct: 302 FATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGW 361
Query: 2563 IDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSD 2742
I EK K+L++ G+D+ V + + E +M + ++ EH S+
Sbjct: 362 IREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSE 421
Query: 2743 DILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDAL 2922
I R + +WA L + ++ LE A L F+ D + W+ D +++ SD +
Sbjct: 422 KIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSD-V 480
Query: 2923 TNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVW 3102
+D L ++ + ++ + LD+LH++A + +E E+ +R + I + +
Sbjct: 481 GHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHA-ESPDVRGRLSGIEERY 539
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
+ + R + L + L + + D + W+ ++ + + + P+ L + E + ++
Sbjct: 540 KEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRF 599
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHL 3462
++ E++ A + + R P ++ + L W + + + D ++
Sbjct: 600 ESLEPEMNNQASRVAVVNQIA-RQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDA 658
Query: 3463 LSQGLNLQMFLRDAKQAEVMLSQQENYL-AKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
L L++Q + + + + + ++ + + D+ L ++ + A +
Sbjct: 659 LLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEA 718
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K+ + ++L + A I + I + + + L +A LQQFL D
Sbjct: 719 KLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRD 778
Query: 3820 CDELREWIEEKMIRAQDETYRDAKTITSKFV-RHQAFQSELAANKERLDQLKHAA--INL 3990
D+ + W+ E + T K + +H+ ++E+ +E +++ +
Sbjct: 779 LDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQ 838
Query: 3991 GDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLE 4170
G +Y + +++ L T W+EL K E + L ++ Q +++ + + E
Sbjct: 839 GQTDAQYM-FLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQE 897
Query: 4171 NEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAH 4350
+ + P L A++KQ T M + I+ + I+
Sbjct: 898 YVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEK 957
Query: 4351 RLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPD 4530
++ ++ ++ + + L+ + +F +D + LWI+E+++ A+ + E+ +
Sbjct: 958 VDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEAR-N 1016
Query: 4531 CHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEA 4710
H Q E+ +++ W+++I G +LI E ++K+ L W+ L+
Sbjct: 1017 LHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLEST 1076
Query: 4711 VKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSD 4890
+ + L ++ KA F C + + W+ E + D+ GKD S +KK + L++
Sbjct: 1077 TQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQ 1136
Query: 4891 IDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXX 5070
++ I L ++A +E T+++ ++ ++ + L +
Sbjct: 1137 MEVRKKEIEELQSQAQALSQE-GKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEI 1195
Query: 5071 YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTE 5214
+ +R+++D + W+ ++ +A S ++G + + VQ+L ++ Q ++ +
Sbjct: 1196 HQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQ 1243
Score = 201 bits (510), Expect = 3e-49
Identities = 221/1184 (18%), Positives = 471/1184 (39%), Gaps = 35/1184 (2%)
Frame = +1
Query: 2815 NELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMER----- 2979
N +E +E + + + WIE +T ++ ++ N L GV + + +
Sbjct: 4 NAIETEKMIEKYESLASDLLEWIE-QTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPP 62
Query: 2980 ---DLGAIQAKLDSLHKE--ADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKL 3144
+ G ++ L ++ + A++ + P+E + I + I++ W+ L K EHE +L
Sbjct: 63 KFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISD----INKAWERLEKA--EHEREL 116
Query: 3145 DEAGDL----------QRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIR 3294
+L +RF R + WL+ QR V+ + L E +H AI
Sbjct: 117 ALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIE 176
Query: 3295 EEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQG 3474
+I Y E + + A+ R + + + R + WE L + R+ L
Sbjct: 177 TDIAAYEERVQAVVAVA-RELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMN 235
Query: 3475 LNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAV 3654
L LQ ++ + + + + D + L E+ L++H + E++R V
Sbjct: 236 LGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGV 295
Query: 3655 GMFGDQLCQDGH----YAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDC 3822
+ DG I + +++ + A E +L+++ L +F +
Sbjct: 296 NASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEM 355
Query: 3823 DELREWIEEK-MIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
E WI EK I + D+ +D ++ +H+AF+ E++ +Q AI G+D
Sbjct: 356 AEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQ----AIKEGED 411
Query: 4000 K--PEYHGT--IDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQL 4167
E+ G+ I +I + QW LE+ + + ++L +A+ + D+ W +
Sbjct: 412 MIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDI 471
Query: 4168 ENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKA 4347
++ D D + ++K + E+ +D H E +++
Sbjct: 472 LKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHA-ESPDVRG 530
Query: 4348 HRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLP 4527
++E+ + + R++AL+ A ++ + D +LWI E+ + E L
Sbjct: 531 RLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLE 590
Query: 4528 DCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKE 4707
D +Q + L E++N + + ++L+ GH + + + +L + W + +E
Sbjct: 591 DLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRE 650
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQ-ELYMMQDERGKDEFSTKNQIKKHERLQ 4884
V +K L + + +C E ++W+ E+ ++ + G D +K ++
Sbjct: 651 LVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGME 710
Query: 4885 SDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXX 5064
D+ + L +A K E + I R A+I ++ ++
Sbjct: 711 RDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEAS 770
Query: 5065 XXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANA 5244
R++DD W++ + S++ + L + + + +N +
Sbjct: 771 KLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMR 830
Query: 5245 NDGCDTLIGHGHTDAPTIALWK--DSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
+ G ++ G TDA + L + +L+ W L ++ + R +L S +F D +
Sbjct: 831 DMG--EMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQ 888
Query: 5419 CLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQV-AQIERDAAELRDGY 5592
+ + + + + ++ A +K ++++ + A E++ A +E + DG
Sbjct: 889 AEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGN 948
Query: 5593 AGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREM 5772
+ + + R R RL D DL KF+ ++L LW++E + +
Sbjct: 949 INSDRIQ--EKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINE--KML 1004
Query: 5773 NSQERPKDVS-GVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLI 5949
+Q+ D + + HQ+ AE+ + +E + G L++ K + +++KL
Sbjct: 1005 TAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLT 1064
Query: 5950 KLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETI 6129
L + + + + L + F + A + WL E + S +YG++L
Sbjct: 1065 GLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVN 1124
Query: 6130 KLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
L+KK + E +++ L+ +E + +E +KR
Sbjct: 1125 ILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKR 1168
>gi|28277312|gb|AAH46267.1| LOC398511 protein [Xenopus laevis]
Length = 1060
Score = 1072 bits (2772), Expect = 0.0
Identities = 540/1035 (52%), Positives = 730/1035 (70%), Gaps = 1/1035 (0%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGK 216
D+D+D +NSSARLFERSRIKALADERE VQKKTFTKWVNSHL RV+C++ DLY D+RDG+
Sbjct: 30 DDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVTCRISDLYNDLRDGR 89
Query: 217 MLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLT 396
ML+RLL VLSGE+LPKPT G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLT
Sbjct: 90 MLIRLLEVLSGEQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLT 149
Query: 397 LGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGL 576
LGLIWTIILRFQIQDI+ E DN E +SAK+ALLLWCQMKTAGYPNVNV NF+TSWRDGL
Sbjct: 150 LGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGL 209
Query: 577 AFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSI 756
AFNA++HKHRPD++D++ L+KSNA +NLQ+AF+ AE +LGL K LD EDVNVDQPDEKSI
Sbjct: 210 AFNAIVHKHRPDIIDFNTLKKSNAHHNLQNAFNVAERELGLTKLLDPEDVNVDQPDEKSI 269
Query: 757 ITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLN 936
ITYV T+YHYF+K+K ++GKRIGKV+++ +E D++I YE L+S+LL+WI I LN
Sbjct: 270 ITYVATFYHYFSKMKALAVEGKRIGKVLDQAIEADQLIENYERLASELLQWIEQMIITLN 329
Query: 937 ERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREG 1116
+R N+L GVQ QL FN YRT EKPPKF EKG LEVLLFT+QS MRANNQ+ + PREG
Sbjct: 330 DRKLANSLSGVQNQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYTPREG 389
Query: 1117 KLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVS 1296
KLI+DIN+AW+ LEKAEHEREL L+ ELIRQEKLEQLAARF+RKA MRETWL+ENQRLV+
Sbjct: 390 KLISDINKAWERLEKAEHERELALRNELIRQEKLEQLAARFDRKAAMRETWLSENQRLVA 449
Query: 1297 QDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENV 1476
QDNFG DL++VEAA +KHEAIETDI AY ER NYHD +I RK NV
Sbjct: 450 QDNFGVDLAAVEAALRKHEAIETDILAYSERVQAVNAVADELEAENYHDVRRILARKCNV 509
Query: 1477 XXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDL 1656
ARR RL +++ +Q++F +K RL S+D G HL VEDL
Sbjct: 510 IRLSDYLRELVTARRQRLHMNLELQRMFQDLHYLMDWTEDMKGRLQSQDYGKHLHGVEDL 569
Query: 1657 LQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
LQ H L+E+DI + ERV + A AQ+F D GYKP +P + R +L++RY E
Sbjct: 570 LQTHTLVEADIAVQAERVKSVTAVAQKFMTED----EGYKPCDPELVRNRVHLLEQRYAE 625
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L +L+A R+ +LE+++RL +F+WD+AE E I+EQ ++L S D G+D+ + L++KH
Sbjct: 626 LCELSAARRSKLEESRRLWKFFWDMAEEEAWIREQSRLLLSDDYGKDLTSSLRLISKHNA 685
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
+ + L + G+EL + G+ I ++ E++D +++ L+ R+ RL
Sbjct: 686 FRDEMSGHRGPLQQTVAEGEELISKGHFGAGEIEEKIKEVKDQWKEMEALAEDRERRLRE 745
Query: 2197 GVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKV 2376
YYQF DA+D + ++ DTLR++S+ +VG DE + Q L+KKH ++ +E+ + I
Sbjct: 746 AYSYYQFQADANDAEAWILDTLRLVSTSEVGHDEYSTQTLVKKHKEIEEEILSHRPAIDA 805
Query: 2377 LHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVE 2556
LH +A LP + P++ RL ++ EL L+ RKQ L D+L+L+K++S++D+
Sbjct: 806 LHEQARGLPSAYSQSPEVDGRLPALEQRYEELVALAAHRKQALQDSLALHKMFSESDACL 865
Query: 2557 SWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN 2736
WIDEK + L +E++E+++ RF+TLE +M N +++ +VN++A QLL+ + N
Sbjct: 866 LWIDEKEQWLNVTEIPEKLEDLEVVQQRFETLEAEMNNLASRIASVNEVAGQLLSTDQRN 925
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
I Q++LN+RW + R +VDQK + L+ A ++ + ++C ETV W+ +KT+V+E +
Sbjct: 926 EKSIRDMQDQLNSRWNEFRRLVDQKGSALDSALDIQNYHLECNETVCWMREKTKVIESTQ 985
Query: 2917 ALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQ 3096
+L NDL+GV LQR+L+ MERDL AIQ K+ L +A+ + P++A AI + I +
Sbjct: 986 SLGNDLAGVTALQRKLTGMERDLKAIQGKVGDLRSDAEKLAAGHPEKAPAITGRLSDIDE 1045
Query: 3097 VWDILNKKVREHEAK 3141
W L +++ + K
Sbjct: 1046 TWGELKDTMKKKKKK 1060
Score = 196 bits (498), Expect = 7e-48
Identities = 154/652 (23%), Positives = 286/652 (43%), Gaps = 13/652 (1%)
Frame = +1
Query: 3745 ANREKAQEVLKKLKDALSLQQFLSDCDE---LRE-WIEEKM-IRAQDETYRDAKTITSKF 3909
A E+ + +L L+Q + D +RE W+ E + AQD D + +
Sbjct: 405 AEHERELALRNELIRQEKLEQLAARFDRKAAMRETWLSENQRLVAQDNFGVDLAAVEAAL 464
Query: 3910 VRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGT--IDPQIEELATQWDELEKTTEE 4083
+H+A ++++ A ER+ + A L + YH I + + D L +
Sbjct: 465 RKHEAIETDILAYSERVQAVNAVADEL--EAENYHDVRRILARKCNVIRLSDYLRELVTA 522
Query: 4084 KGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIK 4263
+ Q+L Q Q + + +W ++ + +D L V +Q L+E ++
Sbjct: 523 RRQRLHMNLELQRMFQDLHYLMDWTEDMKGRLQSQDYGKHLHGVEDLLQTHTLVEADIAV 582
Query: 4264 KAQHIDXXXXXXXXXXXXH----PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
+A+ + P + E ++ ++++ L RR LE +
Sbjct: 583 QAERVKSVTAVAQKFMTEDEGYKPCDPELVRNRVHLLEQRYAELCELSAARRSKLEESRR 642
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
++F D+ +E+ WI E+ L + + G+ L RL +E+ H + Q
Sbjct: 643 LWKFFWDMAEEEAWIREQSRLLLSDDYGKDLTSSLRLISKHNAFRDEMSGHRGPLQQTVA 702
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
G+ELI +GH E+KI+E++ W+E++ +DR+ L E+ +QF D +AEAW
Sbjct: 703 EGEELISKGHFGAGEIEEKIKEVKDQWKEMEALAEDRERRLREAYSYYQFQADANDAEAW 762
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+ + + E G DE+ST+ +KKH+ ++ +I I AL +A S +
Sbjct: 763 ILDTLRLVSTSEVGHDEYSTQTLVKKHKEIEEEILSHRPAIDALHEQARGLPSAYSQ-SP 821
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENG 5151
++ R +E+ Y L + + E D L WI +KE E
Sbjct: 822 EVDGRLPALEQRYEELVALAAHRKQALQDSLALHKMFSESDACLLWIDEKEQWLNVTEIP 881
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
+ E ++++Q+RF+ + N+ S R+A+ N+ L+ + +I +D LN W
Sbjct: 882 EKLEDLEVVQQRFETLEAEMNNLAS-RIASVNEVAGQLLSTDQRNEKSIRDMQDQLNSRW 940
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM--PDDLGRDSSSVGALSRK 5505
L+D + L+++ + ++ +C + + + EKT + LG D + V AL RK
Sbjct: 941 NEFRRLVDQKGSALDSALDIQNYHLECNETVCWMREKTKVIESTQSLGNDLAGVTALQRK 1000
Query: 5506 HQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLR 5661
+D+ AI +V + DA +L G+ +KA I R S++ + W L+
Sbjct: 1001 LTGMERDLKAIQGKVGDLRSDAEKLAAGHP-EKAPAITGRLSDIDETWGELK 1051
Score = 172 bits (437), Expect = 8e-41
Identities = 176/787 (22%), Positives = 337/787 (42%), Gaps = 29/787 (3%)
Frame = +1
Query: 1822 KRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLL 2001
KR ++LD A E + +E+ +RL +EL I++ L+ + V + L
Sbjct: 291 KRIGKVLDQAIEADQLIENYERLA------SELLQWIEQMIITLNDRKLANSLSGVQNQL 344
Query: 2002 AKHKNAENNLRDLEK-----YLDRLDVSGKELQDESIPGSDNI-PPRLAEIRDYINKLKE 2163
A N R +EK L+V +Q + + + PR ++ INK E
Sbjct: 345 ----QAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLISDINKAWE 400
Query: 2164 L--SASRKERLAGGVEYYQ----------FFTDADDVDRYLYDTLRVMSSEDVGKDEGTV 2307
A + LA E + F A + +L + R+++ ++ G D V
Sbjct: 401 RLEKAEHERELALRNELIRQEKLEQLAARFDRKAAMRETWLSENQRLVAQDNFGVDLAAV 460
Query: 2308 QLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQ---RLDTTLKQKAELEN 2478
+ L+KH+ + ++ + + ++ ++A A+ L EA + D+R+ R ++ L
Sbjct: 461 EAALRKHEAIETDILAYSERVQAVNAVADEL--EAENYHDVRRILARKCNVIRLSDYLRE 518
Query: 2479 LSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQ 2658
L R+QRL L L +++ D + W ++ L + G+ + VE + +E
Sbjct: 519 LVTARRQRLHMNLELQRMFQDLHYLMDWTEDMKGRLQSQDYGKHLHGVEDLLQTHTLVEA 578
Query: 2659 DMKNQEAKVTNVNDLARQLLNVEHP----NSDDILHRQNKLNARWAQLRDMVDQKRNELE 2826
D+ Q +V +V +A++ + + + + + +R + L R+A+L ++ +R++LE
Sbjct: 579 DIAVQAERVKSVTAVAQKFMTEDEGYKPCDPELVRNRVHLLEQRYAELCELSAARRSKLE 638
Query: 2827 RAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKL 3006
+ RL F D E WI +++R+L SD DL+ ++L + + ++ + L
Sbjct: 639 ESRRLWKFFWDMAEEEAWIREQSRLLL-SDDYGKDLTSSLRLISKHNAFRDEMSGHRGPL 697
Query: 3007 DSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLD 3186
E +++ + A I E IK + W + + E +L EA +F D +
Sbjct: 698 QQTVAEGEELISKGHFGAGEIEEKIKEVKDQWKEMEALAEDRERRLREAYSYYQFQADAN 757
Query: 3187 HFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGY--AEDYKKMRAMGDRVTQ 3360
+AW+ T R V++ E + L+ +H I EEI + A D +A G
Sbjct: 758 DAEAWILDTLRLVSTSEVGHDEYSTQTLVKKHKEIEEEILSHRPAIDALHEQARGLPSAY 817
Query: 3361 DQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
Q+ + RL L++ +EEL + +R+ L L L ++ + + ++E
Sbjct: 818 SQSPE----VDGRLPALEQRYEELVALAAHRKQALQDSLALHKMFSESDACLLWIDEKEQ 873
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
+L +IP+ LE E +R + M+ +I +V QL I
Sbjct: 874 WLNVTEIPEKLEDLEVVQQRFETLEAEMNNLASRIASVNEVAGQLLSTDQRNEKSIRDMQ 933
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEE--KMIRAQDETYRDAKT 3894
++ R R + L AL +Q + +C+E W+ E K+I + D
Sbjct: 934 DQLNSRWNEFRRLVDQKGSALDSALDIQNYHLECNETVCWMREKTKVIESTQSLGNDLAG 993
Query: 3895 ITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKT 4074
+T+ + + +L A + ++ L+ A L PE I ++ ++ W EL+ T
Sbjct: 994 VTALQRKLTGMERDLKAIQGKVGDLRSDAEKLAAGHPEKAPAITGRLSDIDETWGELKDT 1053
Query: 4075 TEEKGQK 4095
++K +K
Sbjct: 1054 MKKKKKK 1060
Score = 140 bits (352), Expect = 6e-31
Identities = 132/666 (19%), Positives = 261/666 (38%), Gaps = 15/666 (2%)
Frame = +1
Query: 3400 LAGLQEGWEELQRMWDNRQHLLSQGLNLQ--------MFLRDAKQAEVMLSQQENYLAKD 3555
++ + + WE L++ R+ L L Q F R A E LS+ + +A+D
Sbjct: 392 ISDINKAWERLEKAEHERELALRNELIRQEKLEQLAARFDRKAAMRETWLSENQRLVAQD 451
Query: 3556 DIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDE 3735
+ L E L++H+ T + A E+++AV D+L + ++ +I + N+
Sbjct: 452 NFGVDLAAVEAALRKHEAIETDILAYSERVQAVNAVADELEAENYHDVRRILARKCNVIR 511
Query: 3736 RRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFV 3912
RE ++L L LQ+ D L +W E+ R Q + Y + +
Sbjct: 512 LSDYLRELVTARRQRLHMNLELQRMFQDLHYLMDWTEDMKGRLQSQDYGKHLHGVEDLLQ 571
Query: 3913 RHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQ-----IEELATQWDELEKTT 4077
H ++++A ER+ + A + Y DP+ + L ++ EL + +
Sbjct: 572 THTLVEADIAVQAERVKSVTAVAQKFMTEDEGYK-PCDPELVRNRVHLLEQRYAELCELS 630
Query: 4078 EEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEM 4257
+ KL ++ R + +A+ + W + + +D DLT+ + K + EM
Sbjct: 631 AARRSKLEESRRLWKFFWDMAEEEAWIREQSRLLLSDDYGKDLTSSLRLISKHNAFRDEM 690
Query: 4258 IKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAF 4437
+ I+ V++Q + ++A +DR + L + +
Sbjct: 691 SGHRGPLQQTVAEGEELISKGHFGAGEIEEKIKEVKDQWKEMEALAEDRERRLREAYSYY 750
Query: 4438 QFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNG 4617
QF D +D + WI + L L +G L K + + EI +H P I+ +
Sbjct: 751 QFQADANDAEAWILDTLRLVSTSEVGHDEYSTQTLVKKHKEIEEEILSHRPAIDALHEQA 810
Query: 4618 QELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMS 4797
+ L ++ P + ++ L ++EL RK L +S H+ + W+
Sbjct: 811 RGL-PSAYSQSPEVDGRLPALEQRYEELVALAAHRKQALQDSLALHKMFSESDACLLWID 869
Query: 4798 EQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQI 4977
E+E ++ E + + ++ E L+++++ A I ++ A + + + I
Sbjct: 870 EKEQWLNVTEIPEKLEDLEVVQQRFETLEAEMNNLASRIASVNEVAGQLLSTDQRNEKSI 929
Query: 4978 QVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADK-EVVAGSQENGQ 5154
+ Q Q+ + + H E ++ + W+ +K +V+ +Q G
Sbjct: 930 RDMQDQLNSRWNEFRRLVDQKGSALDSALDIQNYHLECNETVCWMREKTKVIESTQSLGN 989
Query: 5155 DYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWE 5334
D V LQ + RD + I +V + + L AP I ++E W
Sbjct: 990 DLAGVTALQRKLTGMERDLKAI-QGKVGDLRSDAEKLAAGHPEKAPAITGRLSDIDETWG 1048
Query: 5335 NLLELM 5352
L + M
Sbjct: 1049 ELKDTM 1054
Score = 103 bits (256), Expect = 8e-20
Identities = 91/374 (24%), Positives = 159/374 (42%), Gaps = 8/374 (2%)
Frame = +1
Query: 5107 WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTD 5286
W+++ + + G D V+ + + D SERV N D L + D
Sbjct: 440 WLSENQRLVAQDNFGVDLAAVEAALRKHEAIETDILAY-SERVQAVNAVADELEAENYHD 498
Query: 5287 APTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--- 5457
I K ++ + L EL+ R Q L + L + + D L +M+ T M
Sbjct: 499 VRRILARKCNVIRLSDYLRELVTARRQRLHMNLELQRMFQD----LHYLMDWTEDMKGRL 554
Query: 5458 --DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALD---IGS 5622
D G+ V L + H DIA E+V + A + G K D + +
Sbjct: 555 QSQDYGKHLHGVEDLLQTHTLVEADIAVQAERVKSVTAVAQKFMTEDEGYKPCDPELVRN 614
Query: 5623 RESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVS 5802
R + + + L L AR S+L ++ L+KF + + W+ E R + S + KD++
Sbjct: 615 RVHLLEQRYAELCELSAARRSKLEESRRLWKFFWDMAEEEAWIREQSRLLLSDDYGKDLT 674
Query: 5803 GVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMR 5982
L++ H + + E+ ++ G +L+++ H+ + EIE+K+ ++ + EM
Sbjct: 675 SSLRLISKHNAFRDEMSGHRGPLQQTVAEGEELISKGHFGAGEIEEKIKEVKDQWKEMEA 734
Query: 5983 RWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
EDR L+ YQF DA AE+W+ + + E G + T L+KKH+ E+
Sbjct: 735 LAEDRERRLREAYSYYQFQADANDAEAWILDTLRLVSTSEVGHDEYSTQTLVKKHKEIEE 794
Query: 6163 SAFAQEERFLALEK 6204
+ AL +
Sbjct: 795 EILSHRPAIDALHE 808
Score = 97.4 bits (241), Expect = 4e-18
Identities = 114/616 (18%), Positives = 235/616 (37%), Gaps = 15/616 (2%)
Frame = +1
Query: 4360 VQEQLQRLQAPLDDRRKALERK--------KAAFQFGRDVDDEKLWISERLVLAKAQNLG 4515
+ + +RL+ +R AL + + A +F R + W+SE L N G
Sbjct: 395 INKAWERLEKAEHERELALRNELIRQEKLEQLAARFDRKAAMRETWLSENQRLVAQDNFG 454
Query: 4516 ESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEG-HANGPAFEKKIQELRSAW 4692
L + + + +I + + + EL E H +K +R +
Sbjct: 455 VDLAAVEAALRKHEAIETDILAYSERVQAVNAVADELEAENYHDVRRILARKCNVIRLS- 513
Query: 4693 QELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKH 4872
L+E V R+ L + + + D W + + + + GK ++ ++ H
Sbjct: 514 DYLRELVTARRQRLHMNLELQRMFQDLHYLMDWTEDMKGRLQSQDYGKHLHGVEDLLQTH 573
Query: 4873 ERLQSDIDKFADTIRALATKAHKFVEE----KSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
+++DI A+ ++++ A KF+ E K E ++ R +E+ YA L +
Sbjct: 574 TLVEADIAVQAERVKSVTAVAQKFMTEDEGYKPCDPELVRNRVHLLEQRYAELCELSAAR 633
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
+ ++ + WI ++ + S + G+D L + F +
Sbjct: 634 RSKLEESRRLWKFFWDMAEEEAWIREQSRLLLSDDYGKDLTSSLRLISKHNAFRDEMSGH 693
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
+G + LI GH A I + + W+ + L + R + L + ++F
Sbjct: 694 RGPLQQTVAEG-EELISKGHFGAGEIEEKIKEVKDQWKEMEALAEDRERRLREAYSYYQF 752
Query: 5401 YHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAE 5577
D D + I++ + ++G D S L +KH+ ++I + + + A
Sbjct: 753 QADANDAEAWILDTLRLVSTSEVGHDEYSTQTLVKKHKEIEEEILSHRPAIDALHEQARG 812
Query: 5578 LRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDE 5757
L Y+ +D R + + + L L R L D+ L K + LLW+DE
Sbjct: 813 LPSAYSQSPEVD--GRLPALEQRYEELVALAAHRKQALQDSLALHKMFSESDACLLWIDE 870
Query: 5758 VKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIE 5937
++ +N E P+ + +E++ ++L+AE++ + + LL+ I
Sbjct: 871 KEQWLNVTEIPEKLEDLEVVQQRFETLEAEMNNLASRIASVNEVAGQLLSTDQRNEKSIR 930
Query: 5938 KKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLIS-KEYGRN 6114
+L + E R + + L L++ + + W+ + + S + G +
Sbjct: 931 DMQDQLNSRWNEFRRLVDQKGSALDSALDIQNYHLECNETVCWMREKTKVIESTQSLGND 990
Query: 6115 LEETIKLIKKHEAFEK 6162
L L +K E+
Sbjct: 991 LAGVTALQRKLTGMER 1006
Score = 41.6 bits (96), Expect = 0.27
Identities = 44/190 (23%), Positives = 83/190 (43%), Gaps = 16/190 (8%)
Frame = +1
Query: 5716 FMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLM---NNHQSLKAEIDAREE-NFNACI 5883
+ + +LL W++++ +N ++ +SGV+ + N +++++ E+ N +
Sbjct: 310 YERLASELLQWIEQMIITLNDRKLANSLSGVQNQLQAFNTYRTVEKPPKFTEKGNLEVLL 369
Query: 5884 SLGRDLL---NRKHYAS------SEIEK---KLIKLTTERAEMMRRWEDRWEYLQLILEV 6027
+ + N+K Y S+I K +L K ER +R R E L+ +
Sbjct: 370 FTIQSKMRANNQKVYTPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLAA- 428
Query: 6028 YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 6207
+F R AA+ E+WL + + +G +L ++KHEA E A ER A+ +
Sbjct: 429 -RFDRKAAMRETWLSENQRLVAQDNFGVDLAAVEAALRKHEAIETDILAYSERVQAVNAV 487
Query: 6208 TTFELKETQH 6237
E H
Sbjct: 488 ADELEAENYH 497
>gi|10047361|dbj|BAB13468.1| KIAA1642 protein [Homo sapiens]
Length = 1997
Score = 1061 bits (2743), Expect = 0.0
Identities = 627/1766 (35%), Positives = 970/1766 (54%), Gaps = 33/1766 (1%)
Frame = +1
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
R FVPREG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL
Sbjct: 1 RLFVPREGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWL 60
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
ENQRLVSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D +
Sbjct: 61 NENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRR 120
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
+ ++++V ARR RLE ++A+QK+F ++++LLS + G
Sbjct: 121 VAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQ 180
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HL++ +DLLQKH LLE DI ERV A A RF G Y+P +P I R +
Sbjct: 181 HLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQLQG-----YQPCDPQVICNRVN 235
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------- 1971
+ EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 236 HVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAG 295
Query: 1972 --------RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESI---PGSDNI- 2115
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 296 AAGTAGGAHDLSSTARLLAQHKILQGELGGRRALLQQALRCGEELVAAGGAVGPGADTVH 355
Query: 2116 ----PPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSED 2283
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D
Sbjct: 356 LVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGD 415
Query: 2284 VGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTL 2454
G DE + + L ++H + E++ + L + +L + P ++ R+
Sbjct: 416 FGHDEASSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAE 475
Query: 2455 KQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMK 2634
+ AE+ ++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++
Sbjct: 476 QLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQ 535
Query: 2635 HRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKR 2814
HRF++L+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++
Sbjct: 536 HRFESLDQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRK 595
Query: 2815 NELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAI 2994
E+ +E ++ E + +K R +E + LQ RLS +E L A+
Sbjct: 596 EEMSAVLLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQAL 649
Query: 2995 QAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFL 3174
+ + +L +EA + P +A + + + + W L + + AG LQRFL
Sbjct: 650 EPRQAALLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFL 709
Query: 3175 RDLDHFQAWLTATQRQVASEEEP--QSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
DLD F WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A +
Sbjct: 710 HDLDAFLDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASE 769
Query: 3349 RVTQD---QTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEV 3519
+ + P + L + L L+ GW +L +W+ R+ L Q Q+FLRD +QA V
Sbjct: 770 ALLAADGAELGPG-LALDEWLPHLELGWHKLLGLWEARREALVQAHIYQLFLRDLRQALV 828
Query: 3520 MLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAA 3699
+L QE L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+
Sbjct: 829 VLRNQEMALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYG 888
Query: 3700 DKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY 3879
++ + + E+ N+ +AQ+ ++KL D L LQ FL DC EL WI EKM+ A+D T
Sbjct: 889 EQAQEAVTRLLEKNQENQLRAQQWMQKLHDQLELQHFLRDCHELDGWIHEKMLMARDGTR 948
Query: 3880 RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWD 4059
D + +++RHQAF +ELA NKE L++++ L +KPE ++ ++ E+ W
Sbjct: 949 EDNHKLHKRWLRHQAFMAELAQNKEWLEKIEREGQQLMQEKPELAASVRKKLGEIRQCWA 1008
Query: 4060 ELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQH 4239
ELE TT+ K ++LF+A++ VQS A++ + +E+++ D GDL TVN ++K
Sbjct: 1009 ELESTTQAKARQLFEASKADQLVQSFAELDKKLLHMESQLQDVDPGGDLATVNSQLKKLQ 1068
Query: 4240 LIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALE 4419
+E+++ + + + P E + + AV E+L RL PL +RR+ L
Sbjct: 1069 SMESQVEEWYREVGELQAQTAALPL-EPASKELVGERQNAVGERLVRLLEPLQERRRLLL 1127
Query: 4420 RKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWIN 4599
K Q D+DDE W+ ERL LA G L + K Q L EI H P +
Sbjct: 1128 ASKELHQVAHDLDDELAWVQERLPLAMQTERGNGLQAVQQHIKKNQGLRREIQAHGPRLE 1187
Query: 4600 QICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGE 4779
++ L A + +++L+SAW L+EA + R+ L + + Q+ +D E
Sbjct: 1188 EVLERAGALASLRSPEAEAVRRGLEQLQSAWAGLREAAERRQQVLDAAFQVEQYYFDVAE 1247
Query: 4780 AEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKS 4959
EAW+ EQEL MM +++GKDE ST +KKH +L+ ++ + ++I L+ + +E
Sbjct: 1248 VEAWLGEQELLMMSEDKGKDEQSTLQLLKKHLQLEQGVENYEESIAQLSRQCRALLEMGH 1307
Query: 4960 PLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGS 5139
P +EQI RQ+Q+++LY L++ Y L R++ +L WIA+KEVVAGS
Sbjct: 1308 PDSEQISRRQSQVDRLYVALKELGEERRVALEQQYWLYQLSRQVSELEHWIAEKEVVAGS 1367
Query: 5140 QENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSL 5319
E GQD+EHV +LQE+F +FA +T G ER+A N D LI GHT A T+A WKD L
Sbjct: 1368 PELGQDFEHVSVLQEKFSEFASETGMAGRERLAAVNQMVDELIECGHTAAATMAEWKDGL 1427
Query: 5320 NEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP--DDLGRDSSSVGA 5493
NEAW LLELM TRAQ+L ASR LHKF+ D R+ +I EK +P S +
Sbjct: 1428 NEAWAELLELMGTRAQLLAASRELHKFFSDARELQGQIEEKRRRLPRLTTPPEPRPSASS 1487
Query: 5494 LSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCD 5673
+ R + + D+ + QV Q++ AA+LR YAG+ A I SRE EV++ W+ L C+
Sbjct: 1488 MQRTLRAFEHDLQLLVSQVRQLQEGAAQLRTVYAGEHAEAIASREQEVLQGWKELLSACE 1547
Query: 5674 ARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEID 5853
+ T+D +F + VRDLL WMD + ++ + ++P+DVS VE+LMN HQ LK E++
Sbjct: 1548 DARLHVSSTADALRFHSQVRDLLSWMDGIASQIGAADKPRDVSSVEVLMNYHQGLKTELE 1607
Query: 5854 AREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQ 6033
AR C LGR LL K + EI+ +L KL T + E+ +W+ WE+LQ +LEV+Q
Sbjct: 1608 ARVPELTTCQELGRSLLLNKSAMADEIQAQLDKLGTRKEEVSEKWDRHWEWLQQMLEVHQ 1667
Query: 6034 FARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
FA++A VA++WL AQEP L S+E G +++E +LI++HEAF K+A A EERF +L +LTT
Sbjct: 1668 FAQEAVVADAWLTAQEPLLQSRELGSSVDEVEQLIRRHEAFRKAAAAWEERFSSLRRLTT 1727
Query: 6214 FELKETQHREEETAKRRGPAHIGSPS 6291
E + + ++ G G P+
Sbjct: 1728 IEKIKAEQSKQPPTPLLGRKFFGDPT 1753
>gi|47210379|emb|CAF95574.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2307
Score = 1059 bits (2738), Expect = 0.0
Identities = 599/1519 (39%), Positives = 876/1519 (57%), Gaps = 67/1519 (4%)
Frame = +1
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
R+ +LE R +F A E + E ++++S + G D+ V KH+ E ++
Sbjct: 510 RQEKLEQLAR--RFDRKAAMREAWLSENQRLVSQDNFGLDLQAVEAATKKHEAIETDIAA 567
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
E+ + + +EL+ E + R + L EL +R+ RL + +
Sbjct: 568 YEERVQAVVAVARELEAERYHDIKRVAARKENVLRLWEYLLELLKARRRRLEKNLGLQRL 627
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES 2397
F + + ++ D ++V+ LH +A +
Sbjct: 628 FQEMLHIMDWM-DEMKVLGGSGA------------------------------LHEQAAA 656
Query: 2398 LPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKG 2577
LP A+E P + RL ++ E+ L++LRKQ L DAL+LY++ S+AD+ + WI EK
Sbjct: 657 LP--AQEAPHVHARLAGIEERYREVAELTKLRKQALQDALALYRMLSEADACQRWIAEKE 714
Query: 2578 KLL-ATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILH 2754
+ L T +P + +E++E+++HRF++LE +M +Q ++V VN + RQL++ HP DI
Sbjct: 715 QWLHGTRIPEK-LEDLEVVQHRFESLEPEMNHQASRVAVVNQIGRQLVHSGHPGEKDIRT 773
Query: 2755 RQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDL 2934
+Q+KLN RW+Q RD++DQK+ L A ++ + +DC ET +WI +KT+V+E + L NDL
Sbjct: 774 QQDKLNNRWSQFRDLLDQKKESLNSALGVQNYHLDCNETKSWITEKTKVIESTQDLGNDL 833
Query: 2935 SGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILN 3114
+GVM LQR+LS MERDL AI+AKL L EA + E P++A+AI + I VW+ +
Sbjct: 834 TGVMALQRKLSGMERDLAAIEAKLGGLGGEARQLAEEHPEQAEAITGRLLEISAVWEEMK 893
Query: 3115 KKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIR 3294
++ E L EA LQ+FLR+LD FQ+WL+ TQ +ASE+ +LAEAE+L+ QH ++
Sbjct: 894 TTLKNREESLGEARKLQQFLRELDDFQSWLSRTQTAIASEDVANTLAEAEKLMGQHQGLK 953
Query: 3295 EEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQG 3474
EI Y +DY+KMR MG+ VT+ QTD QYMFLRQRL L GW EL RMW+NRQ +LSQ
Sbjct: 954 NEIQNYEDDYQKMRDMGEMVTRGQTDAQYMFLRQRLQALHTGWNELHRMWENRQKVLSQC 1013
Query: 3475 LNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAV 3654
Q+FLRD KQAE L+ QE LA ++ +LE AE +K+ +DF+TTMDAN+EKI V
Sbjct: 1014 HAYQLFLRDTKQAEAFLNSQEYVLAHTEMATTLEGAEAAIKKQEDFMTTMDANEEKISGV 1073
Query: 3655 GMFGDQLCQDGHYAADKIHKKARNIDER------------------RGA----------- 3747
G +L DG+ A++I ++ ++D R RG
Sbjct: 1074 VEAGRRLSSDGNINAERIQERVASLDGRWAPPPGPPGAVGASWARGRGTSEARLLCARQR 1133
Query: 3748 -NREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQA 3924
NRE A E+L +LKD LQ+FL DC EL WI EKM+ AQD +Y +A+ + SK+++HQA
Sbjct: 1134 KNREAAVELLMRLKDNRDLQKFLQDCQELTLWINEKMLSAQDLSYDEARNLHSKWLKHQA 1193
Query: 3925 FQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFD 4104
F +EL +NKE L +++ L +KPE + ++ L T W ELE TT+ K Q LFD
Sbjct: 1194 FMAELQSNKEWLQKIQKDGALLVAEKPEMEAVVTQKLLLLQTMWAELESTTQTKAQCLFD 1253
Query: 4105 ANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDX 4284
AN+ +L+ QS AD+ +W LE ++ +D DLT+V++ ++KQ ++E ++ + + +
Sbjct: 1254 ANKAELFTQSCADLDKWMLGLEGQIQSDDCGKDLTSVSILLKKQQMLENQVEVRQREV-V 1312
Query: 4285 XXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDE 4464
+ + + R ++++ Q L PL RR L + QF RDV+DE
Sbjct: 1313 ELQSQVQALSQEVKDTDEVDGRRQLLEKKFQELLEPLQQRRNLLLASREVHQFNRDVEDE 1372
Query: 4465 KLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHA 4644
LW+ ER+ LA + G +L L K Q L E+ H+P I+ I Q L+ +
Sbjct: 1373 ILWVEERMALATSTEHGSNLQTVQLLIKKNQTLQKEVQGHQPRIDDILERSQGLLQD--- 1429
Query: 4645 NGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQD 4824
A ++++++L+ W L++ + R L E+ A Q+ +D EAEAWMSEQELYMM +
Sbjct: 1430 --QAIQQRLRDLQQLWSRLRQEAELRHARLQEAHHAQQYYFDAAEAEAWMSEQELYMMSE 1487
Query: 4825 ERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEK 5004
E+ KDE S KKH+ L+ ++ +A+T+ L+ + V E P +E+I +RQ+Q++K
Sbjct: 1488 EKAKDEQSAVAMQKKHQILEQAVEDYAETVHQLSKTSRGLVAEGHPESERISMRQSQVDK 1547
Query: 5005 LYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQE 5184
LYA L+D + L+RE+DDL QWIA++EVVAGS E GQDYEHV MLQE
Sbjct: 1548 LYASLKDLSEERRGKLDERLRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQE 1607
Query: 5185 RFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRA 5364
RF++FARDT IG ERV N D LI GH DA T+A WKD LNEAW +LLEL+DTR
Sbjct: 1608 RFREFARDTGTIGQERVDAVNRLADELINGGHGDAATVAEWKDGLNEAWADLLELIDTRT 1667
Query: 5365 QILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGE 5544
QIL AS LHKFY D ++ L R+++K +P++ GRD +V L R H + DI A+G
Sbjct: 1668 QILAASFELHKFYQDAKEILGRVVDKQKKLPEEDGRDHHTVETLQRTHTAFEHDIQALGT 1727
Query: 5545 QVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMN 5724
QV Q++ DAA L+ YAGDKA DI RE EV++AW L C+ R RL+DT D F+F +
Sbjct: 1728 QVRQLQEDAARLQSAYAGDKAEDIQRREGEVLEAWGALLQACERRRLRLLDTGDKFRFFS 1787
Query: 5725 MVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLL 5904
+VRDL+LWM++V R + +QE P+DVS VELLMNNHQ + + + G D
Sbjct: 1788 LVRDLMLWMEDVIRLIQAQEVPRDVSSVELLMNNHQGINGGDRRSQRQLHLLHRAGEDAA 1847
Query: 5905 NRK------------------------HYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQ 6012
++ +I+ +L++LT +R EM+ +WEDRWE+L+
Sbjct: 1848 GQEALRLGGGEGAGLRPGRGRSPPPTLFLLHPQIKDRLLQLTDKRKEMIDKWEDRWEWLR 1907
Query: 6013 L------------ILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
L +L R A AQEPYL S+E GR++++ KL+K+HEAF
Sbjct: 1908 LSKPRPSGPGGAPVLPGRGRGRGLAAG-----AQEPYLSSREVGRSVDQVEKLLKRHEAF 1962
Query: 6157 EKSAFAQEERFLALEKLTT 6213
EKSA EERF ALE+LTT
Sbjct: 1963 EKSAATWEERFSALERLTT 1981
Score = 800 bits (2067), Expect = 0.0
Identities = 583/1943 (30%), Positives = 911/1943 (46%), Gaps = 164/1943 (8%)
Frame = +1
Query: 40 DEDYD-DNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMR--- 207
D+D+D +NSSARLFERSRIKALAD Q+ + + H V V L D R
Sbjct: 27 DDDWDNENSSARLFERSRIKALADRN---QQSVRLQEEDLHQVGQPPPVPGLLQDQRPLH 83
Query: 208 --DGKMLLRLLAVLSGERL-------------------------------------PKPT 270
+G+ A S R PKPT
Sbjct: 84 GPEGRTHADQAAGGSVRRAAGQFTHTHTHTHTHTHTHTHGRSLRLGPEAALLLWFQPKPT 143
Query: 271 PGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQ------ 432
G+MRIHCLENV+K LQFL+ Q VHLEN+GSHDIVDGN RLTLGLIWTIILRFQ
Sbjct: 144 KGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQVFKAGW 203
Query: 433 -------------------------------IQDITFEDADNHETRSAKEALLLWCQMKT 519
IQDI+ E DN E RSAK+ALLLWCQMKT
Sbjct: 204 SLQAHTHTYTHTHTHTPPVQVFLLTLRLRLQIQDISVETEDNKEKRSAKDALLLWCQMKT 263
Query: 520 AGYPNVNVKNFSTSWRDGLAFNALIHKHR------------------PDLVDYDNLQKSN 645
AGYPNVN+ NF+TSWRDG+AFNALIHKHR PDLVD+D L+KSN
Sbjct: 264 AGYPNVNIHNFTTSWRDGMAFNALIHKHRTSSGLGKPPTFILPVLLRPDLVDFDKLKKSN 323
Query: 646 ALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKR 825
A YNLQ+AF+ AE LGL K LD ED++VD PDEKS+ITYVVTYYHYF+K+K ++GKR
Sbjct: 324 AHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSVITYVVTYYHYFSKMKALKVEGKR 383
Query: 826 IGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRT 1005
IGKV++ +E +KMI +YE L+S+LLEWI I +LN R F N+L GVQ+QL FN YRT
Sbjct: 384 IGKVLDHAIEAEKMIQKYEHLASELLEWIEQTIIILNNRKFANSLLGVQQQLQAFNTYRT 443
Query: 1006 QEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELV 1185
EKPPKF EKG LEVLLFT+QS MRANNQ+ ++PREGKLI+DIN+AW+ LEKAEHEREL
Sbjct: 444 VEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYLPREGKLISDINKAWERLEKAEHERELA 503
Query: 1186 LKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIET 1365
L+ ELIRQEKLEQLA RF+RKA MRE WL+ENQRLVSQDNFG DL +VEAATKKHEAIET
Sbjct: 504 LRTELIRQEKLEQLARRFDRKAAMREAWLSENQRLVSQDNFGLDLQAVEAATKKHEAIET 563
Query: 1366 DIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMA 1545
DI AYEER YHD ++ RKENV ARR RLE ++
Sbjct: 564 DIAAYEERVQAVVAVARELEAERYHDIKRVAARKENVLRLWEYLLELLKARRRRLEKNLG 623
Query: 1546 IQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIA 1725
+Q++F H+MD D ++ ++G +
Sbjct: 624 LQRLFQEM--------------------LHIMDWMD----------EMKVLG---GSGAL 650
Query: 1726 QAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWW 1905
Q P E + R +++RY+E+ +L RK+ L+D L +
Sbjct: 651 HEQAAALP---------AQEAPHVHARLAGIEERYREVAELTKLRKQALQDALALYRMLS 701
Query: 1906 DVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQ 2085
+ + I E+EQ L T + + + + ++ E + + ++ G++L
Sbjct: 702 EADACQRWIAEKEQWLHGTRIPEKLEDLEVVQHRFESLEPEMNHQASRVAVVNQIGRQLV 761
Query: 2086 DESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLR 2265
PG +I + ++ + ++ ++L +KE L + + D ++ ++ + +
Sbjct: 762 HSGHPGEKDIRTQQDKLNNRWSQFRDLLDQKKESLNSALGVQNYHLDCNETKSWITEKTK 821
Query: 2266 VM-SSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRL 2442
V+ S++D+G D V L +K + +L + + L +A L A EHP+ + +
Sbjct: 822 VIESTQDLGNDLTGVMALQRKLSGMERDLAAIEAKLGGLGGEARQL---AEEHPEQAEAI 878
Query: 2443 DTTLKQKA----ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRD 2610
L + + E++ + R++ L +A L + + D +SW+ +A+
Sbjct: 879 TGRLLEISAVWEEMKTTLKNREESLGEARKLQQFLRELDDFQSWLSRTQTAIASEDVANT 938
Query: 2611 IEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDIL-HRQNKLNARWAQ 2787
+ E E + + L+ +++N E + D+ + + L R L+ W +
Sbjct: 939 LAEAEKLMGQHQGLKNEIQNYEDDYQKMRDMGEMVTRGQTDAQYMFLRQRLQALHTGWNE 998
Query: 2788 LRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLS 2967
L M + ++ L + H + F D ++ ++ + VL ++ T L G ++
Sbjct: 999 LHRMWENRQKVLSQCHAYQLFLRDTKQAEAFLNSQEYVLAHTEMATT-LEGAEAAIKKQE 1057
Query: 2968 MMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWD-------------- 3105
+ A + K+ + + + + A+ I+E + + W
Sbjct: 1058 DFMTTMDANEEKISGVVEAGRRLSSDGNINAERIQERVASLDGRWAPPPGPPGAVGASWA 1117
Query: 3106 ----------ILNKKVREHEA------KLDEAGDLQRFLRDLDHFQAWLTATQRQVASEE 3237
+ ++ + EA +L + DLQ+FL+D W+ ++ +++++
Sbjct: 1118 RGRGTSEARLLCARQRKNREAAVELLMRLKDNRDLQKFLQDCQELTLWI--NEKMLSAQD 1175
Query: 3238 EPQSLAEAEQLLN---QHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAG 3408
S EA L + +H A E+ E +K++ G + ++ + + + + Q+L
Sbjct: 1176 --LSYDEARNLHSKWLKHQAFMAELQSNKEWLQKIQKDGALLVAEKPEMEAV-VTQKLLL 1232
Query: 3409 LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN 3588
LQ W EL+ + L ++F + + + E + DD + L
Sbjct: 1233 LQTMWAELESTTQTKAQCLFDANKAELFTQSCADLDKWMLGLEGQIQSDDCGKDLTSVSI 1292
Query: 3589 QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
LK+ Q ++ ++ + Q A + K +D RR +K QE
Sbjct: 1293 LLKKQQMLENQVEVRQREVVEL--------QSQVQALSQEVKDTDEVDGRRQLLEKKFQE 1344
Query: 3769 VLKKLKDALSL-------QQFLSDCDELREWIEEKM-IRAQDETYRDAKTITSKFVRHQA 3924
+L+ L+ +L QF D ++ W+EE+M + E + +T+ ++Q
Sbjct: 1345 LLEPLQQRRNLLLASREVHQFNRDVEDEILWVEERMALATSTEHGSNLQTVQLLIKKNQT 1404
Query: 3925 FQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFD 4104
Q E+ ++ R+D + + L D+ I ++ +L W L + E + +L +
Sbjct: 1405 LQKEVQGHQPRIDDILERSQGLLQDQ-----AIQQRLRDLQQLWSRLRQEAELRHARLQE 1459
Query: 4105 ANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQH-LIETEMIKKAQHID 4281
A+ Q Y A+ + W ++ E M E++ D + VAMQK+H ++E + A+ +
Sbjct: 1460 AHHAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSA-VAMQKKHQILEQAVEDYAETVH 1518
Query: 4282 XXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDD 4461
E E I + V + L+ ++RR L+ + FQ R+VDD
Sbjct: 1519 QLSKTSRGLVAEGHPESERISMRQSQVDKLYASLKDLSEERRGKLDERLRLFQLNREVDD 1578
Query: 4462 EKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDN-HEPWINQICNNGQELIDEG 4638
+ WI+ER V+A + LG+ LQ+ + + + + ++ + ELI+ G
Sbjct: 1579 LEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGTIGQERVDAVNRLADELINGG 1638
Query: 4639 HANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMM 4818
H + + L AW +L E + R L S + H+F D E + +++ +
Sbjct: 1639 HGDAATVAEWKDGLNEAWADLLELIDTRTQILAASFELHKFYQDAKEILGRVVDKQ-KKL 1697
Query: 4819 QDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE-KSPLTEQIQVRQAQ 4995
+E G+D + + + H + DI +R L A + E IQ R+ +
Sbjct: 1698 PEEDGRDHHTVETLQRTHTAFEHDIQALGTQVRQLQEDAARLQSAYAGDKAEDIQRREGE 1757
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
+ + + L + + DL+ W+ D + +QE +D V++
Sbjct: 1758 VLEAWGALLQACERRRLRLLDTGDKFRFFSLVRDLMLWMEDVIRLIQAQEVPRDVSSVEL 1817
Query: 5176 L--------------QERFQQFARDTENIGSERV--ANANDGCDTLIGHGHTDAPTIALW 5307
L Q + R E+ + +G G G + PT+ L
Sbjct: 1818 LMNNHQGINGGDRRSQRQLHLLHRAGEDAAGQEALRLGGGEGAGLRPGRGRSPPPTLFLL 1877
Query: 5308 KDSLNEAWENLLELMDTRAQILE 5376
+ + LL+L D R ++++
Sbjct: 1878 HPQIK---DRLLQLTDKRKEMID 1897
Score = 236 bits (601), Expect = 8e-60
Identities = 299/1547 (19%), Positives = 617/1547 (39%), Gaps = 64/1547 (4%)
Frame = +1
Query: 1606 RLLSED-LGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPV 1782
RL+S+D G L VE +KH +E+DI ERV +A A+ + Y +
Sbjct: 537 RLVSQDNFGLDLQAVEAATKKHEAIETDIAAYEERVQAVVAVAREL------EAERYHDI 590
Query: 1783 EPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSST 1962
+ + R + + + ++ LL+L R+RRLE N L + + ++ + + E + + S
Sbjct: 591 K--RVAARKENVLRLWEYLLELLKARRRRLEKNLGLQRLFQEMLHIMDWMDEMKVLGGSG 648
Query: 1963 DTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRD 2142
+ A H +A RLA I +
Sbjct: 649 ALHEQAAALPAQEAPHVHA----------------------------------RLAGIEE 674
Query: 2143 YINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLK 2322
++ EL+ RK+ L + Y+ ++AD R++ + + + + + ++++
Sbjct: 675 RYREVAELTKLRKQALQDALALYRMLSEADACQRWIAEKEQWLHGTRIPEKLEDLEVVQH 734
Query: 2323 KHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAELENLSQLR 2493
+ + + E+ + + V++ L HP DIR + D + ++ +L +
Sbjct: 735 RFESLEPEMNHQASRVAVVNQIGRQLVHSG--HPGEKDIRTQQDKLNNRWSQFRDLLDQK 792
Query: 2494 KQRLIDALSLYKLYSDADSVESWIDEKGKLL-ATLVPGRDIEEVEIMKHRFDTLEQDMKN 2670
K+ L AL + + D + +SWI EK K++ +T G D+ V ++ + +E+D+
Sbjct: 793 KESLNSALGVQNYHLDCNETKSWITEKTKVIESTQDLGNDLTGVMALQRKLSGMERDLAA 852
Query: 2671 QEAKVTNVNDLARQLLNVEHP-NSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLET 2847
EAK+ + ARQL EHP ++ I R +++A W +++ + + L A +L+
Sbjct: 853 IEAKLGGLGGEARQLAE-EHPEQAEAITGRLLEISAVWEEMKTTLKNREESLGEARKLQQ 911
Query: 2848 FRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEA 3027
F + + +W+ +T+ S+ + N L+ KL + ++ ++ + +
Sbjct: 912 FLRELDDFQSWL-SRTQTAIASEDVANTLAEAEKLMGQHQGLKNEIQNYEDDYQKMRDMG 970
Query: 3028 DDIER-ERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWL 3204
+ + R + + +R+ ++ +H W+ L++ + L + Q FLRD +A+L
Sbjct: 971 EMVTRGQTDAQYMFLRQRLQALHTGWNELHRMWENRQKVLSQCHAYQLFLRDTKQAEAFL 1030
Query: 3205 TATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYM 3384
+ + +A E +L AE + + +D E + G R++ D +
Sbjct: 1031 NSQEYVLAHTEMATTLEGAEAAIKKQEDFMTTMDANEEKISGVVEAGRRLSSD-GNINAE 1089
Query: 3385 FLRQRLAGLQEGW--------------------------------------EELQRMWDN 3450
+++R+A L W E L R+ DN
Sbjct: 1090 RIQERVASLDGRWAPPPGPPGAVGASWARGRGTSEARLLCARQRKNREAAVELLMRLKDN 1149
Query: 3451 RQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN---QLKRHQDFITT 3621
R +LQ FL+D + E+ L E L+ D+ S ++A N + +HQ F+
Sbjct: 1150 R--------DLQKFLQDCQ--ELTLWINEKMLSAQDL--SYDEARNLHSKWLKHQAFMAE 1197
Query: 3622 MDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSL 3801
+ +N E ++ + G L + + +K + Q + L DA
Sbjct: 1198 LQSNKEWLQKIQKDGALLVAEKPEMEAVVTQKLLLLQTMWAELESTTQTKAQCLFDANKA 1257
Query: 3802 QQFLSDCDELREWI--EEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKH 3975
+ F C +L +W+ E I++ D+ +D +++ + Q ++++ + + +L+
Sbjct: 1258 ELFTQSCADLDKWMLGLEGQIQS-DDCGKDLTSVSILLKKQQMLENQVEVRQREVVELQS 1316
Query: 3976 AAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEW 4155
L + + +D + + L ++ EL + +++ L + + + + D W
Sbjct: 1317 QVQALSQEVKD-TDEVDGRRQLLEKKFQELLEPLQQRRNLLLASREVHQFNRDVEDEILW 1375
Query: 4156 ATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELE 4335
+ T + +L TV + ++K ++ E+ ID + +
Sbjct: 1376 VEERMALATSTEHGSNLQTVQLLIKKNQTLQKEVQGHQPRIDDILERSQGLL-----QDQ 1430
Query: 4336 NIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLG 4515
I+ +Q+ RL+ + R L+ A Q+ D + + W+SE+ + ++
Sbjct: 1431 AIQQRLRDLQQLWSRLRQEAELRHARLQEAHHAQQYYFDAAEAEAWMSEQELYMMSEEKA 1490
Query: 4516 ESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQ 4695
+ +QK Q+L ++++ ++Q+ + L+ EGH + ++ +
Sbjct: 1491 KDEQSAVAMQKKHQILEQAVEDYAETVHQLSKTSRGLVAEGHPESERISMRQSQVDKLYA 1550
Query: 4696 ELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKD-EFSTKNQIKKH 4872
LK+ ++R+G L E + Q + + E W++E+E+ E G+D E T Q +
Sbjct: 1551 SLKDLSEERRGKLDERLRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFR 1610
Query: 4873 ERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXX 5052
E + + + A+ A + + + + + + +A L +
Sbjct: 1611 EFARDTGTIGQERVDAVNRLADELINGGHGDAATVAEWKDGLNEAWADLLELIDTRTQIL 1670
Query: 5053 XXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSER 5232
+ +++ ++L + DK+ +E+G+D+ V+ LQ F D + +G++
Sbjct: 1671 AASFELHKFYQDAKEILGRVVDKQKKL-PEEDGRDHHTVETLQRTHTAFEHDIQALGTQV 1729
Query: 5233 VANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDC 5412
D + A I + + EAW LL+ + R L + +F+
Sbjct: 1730 RQLQEDAARLQSAYAGDKAEDIQRREGEVLEAWGALLQACERRRLRLLDTGDKFRFFSLV 1789
Query: 5413 RDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDG 5589
RD + + + + ++ RD SSV L HQ Q+ + R +
Sbjct: 1790 RDLMLWMEDVIRLIQAQEVPRDVSSVELLMNNHQGINGGDRRSQRQLHLLHRAGEDA--- 1846
Query: 5590 YAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKRE 5769
AG +AL +G E R RG T LF ++D LL + + ++E
Sbjct: 1847 -AGQEALRLGGGEG---AGLRPGRGRSPPPT--------LFLLHPQIKDRLLQLTDKRKE 1894
Query: 5770 M------------NSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRK 5913
M S+ RP G +L + A+E L +R+
Sbjct: 1895 MIDKWEDRWEWLRLSKPRPSGPGGAPVLPGRGRGRGLAAGAQEPY----------LSSRE 1944
Query: 5914 HYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
S + +KL+K + WE+R+ L+ + V R A +
Sbjct: 1945 VGRSVDQVEKLLKRHEAFEKSAATWEERFSALERLTTVSAGPRRAGL 1991
Score = 209 bits (531), Expect = 1e-51
Identities = 267/1293 (20%), Positives = 501/1293 (38%), Gaps = 85/1293 (6%)
Frame = +1
Query: 2641 FDTLEQDMKNQEAKVTNVNDLARQLL-----------NVEHPNSDDIL-------HRQNK 2766
FD L++ N + N +LA Q L +V+HP+ ++ H +K
Sbjct: 316 FDKLKKS--NAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSVITYVVTYYHYFSK 373
Query: 2767 LNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVM 2946
+ A + + + + +E ++ + E + WIE +T ++ ++ N L GV
Sbjct: 374 MKALKVEGKRIGKVLDHAIEAEKMIQKYEHLASELLEWIE-QTIIILNNRKFANSLLGVQ 432
Query: 2947 KLQRRLSMMER--------DLGAIQAKLDSLHKE--ADDIERERPQEAQAIREDIKRIHQ 3096
+ + + + G ++ L ++ + A++ + P+E + I + I++
Sbjct: 433 QQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYLPREGKLISD----INK 488
Query: 3097 VWDILNKKVREHEAKLDEAGDL----------QRFLRDLDHFQAWLTATQRQVASEEEPQ 3246
W+ L K EHE +L +L +RF R +AWL+ QR V+ +
Sbjct: 489 AWERLEKA--EHERELALRTELIRQEKLEQLARRFDRKAAMREAWLSENQRLVSQDNFGL 546
Query: 3247 SLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEG-- 3420
L E +H AI +I Y E + + A V ++ +Y ++ R+A +E
Sbjct: 547 DLQAVEAATKKHEAIETDIAAYEERVQAVVA----VARELEAERYHDIK-RVAARKENVL 601
Query: 3421 --WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQL 3594
WE L + R+ L + L LQ
Sbjct: 602 RLWEYLLELLKARRRRLEKNLGLQRLF--------------------------------- 628
Query: 3595 KRHQDFITTMDANDEK--IRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
Q+ + MD DE + G +Q A +H + I+ER E +
Sbjct: 629 ---QEMLHIMDWMDEMKVLGGSGALHEQAAALPAQEAPHVHARLAGIEERYREVAELTKL 685
Query: 3769 VLKKLKDALSLQQFLSDCDELREWIEEKMIRAQD----ETYRDAKTITSKFVRHQAFQSE 3936
+ L+DAL+L + LS+ D + WI EK E D + + +F + +
Sbjct: 686 RKQALQDALALYRMLSEADACQRWIAEKEQWLHGTRIPEKLEDLEVVQHRFESLEPEMNH 745
Query: 3937 LAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQ 4116
A+ ++Q+ ++ G + I Q ++L +W + ++K + L A
Sbjct: 746 QASRVAVVNQIGRQLVHSGHPGEK---DIRTQQDKLNNRWSQFRDLLDQKKESLNSALGV 802
Query: 4117 QLYVQSIADMKEWATQLENEM-TREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXX 4293
Q Y + K W T+ + + +D DLT V +K +E ++ +
Sbjct: 803 QNYHLDCNETKSWITEKTKVIESTQDLGNDLTGVMALQRKLSGMERDLAAIEAKLGGLGG 862
Query: 4294 XXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLW 4473
HP++ E I L + + ++ L +R ++L + QF R++DD + W
Sbjct: 863 EARQLAEEHPEQAEAITGRLLEISAVWEEMKTTLKNREESLGEARKLQQFLRELDDFQSW 922
Query: 4474 ISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGP 4653
+S ++++ +L + +L Q L NEI N+E ++ + G E++ G +
Sbjct: 923 LSRTQTAIASEDVANTLAEAEKLMGQHQGLKNEIQNYEDDYQKMRDMG-EMVTRGQTDAQ 981
Query: 4654 AF--EKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDE 4827
+++Q L + W EL ++R+ L + FL D +AEA+++ QE + E
Sbjct: 982 YMFLRQRLQALHTGWNELHRMWENRQKVLSQCHAYQLFLRDTKQAEAFLNSQEYVLAHTE 1041
Query: 4828 RGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKL 5007
+ IKK E + +D + I + + + + E+IQ R A ++
Sbjct: 1042 MATTLEGAEAAIKKQEDFMTTMDANEEKISGVVEAGRRLSSDGNINAERIQERVASLDGR 1101
Query: 5008 YA-----------------GLQDXXXXXXXXXXXXXXXYAL------HREIDDLLQ---- 5106
+A G + L +R++ LQ
Sbjct: 1102 WAPPPGPPGAVGASWARGRGTSEARLLCARQRKNREAAVELLMRLKDNRDLQKFLQDCQE 1161
Query: 5107 ---WIADKEVVAGSQENGQDYEHVQMLQERF---QQFARDTENIGSERVANANDGCDTLI 5268
WI +K + A Y+ + L ++ Q F + ++ DG L+
Sbjct: 1162 LTLWINEKMLSA----QDLSYDEARNLHSKWLKHQAFMAELQSNKEWLQKIQKDGA-LLV 1216
Query: 5269 GHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME-KT 5445
+ L W L T+AQ L + F C D ++ +
Sbjct: 1217 AEKPEMEAVVTQKLLLLQTMWAELESTTQTKAQCLFDANKAELFTQSCADLDKWMLGLEG 1276
Query: 5446 HAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSR 5625
DD G+D +SV L +K Q + +V +++ L +D R
Sbjct: 1277 QIQSDDCGKDLTSVSILLKKQQMLENQVEVRQREVVELQSQVQALSQEVKDTDEVD--GR 1334
Query: 5626 ESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSG 5805
+ K ++ L R + L+ + ++ +F V D +LW++E S E ++
Sbjct: 1335 RQLLEKKFQELLEPLQQRRNLLLASREVHQFNRDVEDEILWVEERMALATSTEHGSNLQT 1394
Query: 5806 VELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRR 5985
V+LL+ +Q+L+ E+ + + + + LL I+++L L + + +
Sbjct: 1395 VQLLIKKNQTLQKEVQGHQPRIDDILERSQGLLQ-----DQAIQQRLRDLQQLWSRLRQE 1449
Query: 5986 WEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKS 6165
E R LQ Q+ DAA AE+W+ QE Y++S+E ++ + + + KKH+ E++
Sbjct: 1450 AELRHARLQEAHHAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVAMQKKHQILEQA 1509
Query: 6166 AFAQEERFLALEKLTTFELKETQHREEETAKRR 6264
E L K T+ L H E E R
Sbjct: 1510 VEDYAETVHQLSK-TSRGLVAEGHPESERISMR 1541
Score = 196 bits (499), Expect = 5e-48
Identities = 169/722 (23%), Positives = 330/722 (45%), Gaps = 36/722 (4%)
Frame = +1
Query: 1597 IKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYK 1776
++ ++ S+D G L V LL+K +LE+ + + V +Q Q +
Sbjct: 1274 LEGQIQSDDCGKDLTSVSILLKKQQMLENQVEVRQREVVELQSQVQALSQ---------E 1324
Query: 1777 PVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLS 1956
+ +D R +L+K+++ELL+ +R+ L ++ + QF DV + ++E+ + +
Sbjct: 1325 VKDTDEVDGRRQLLEKKFQELLEPLQQRRNLLLASREVHQFNRDVEDEILWVEERMALAT 1384
Query: 1957 STDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDR-LDVSGKELQDESIPGSDNIPPRLAE 2133
ST+ G ++ TV L+ K++ + ++ + +D L+ S LQD++I RL +
Sbjct: 1385 STEHGSNLQTVQLLIKKNQTLQKEVQGHQPRIDDILERSQGLLQDQAIQ------QRLRD 1438
Query: 2134 IRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQL 2313
++ ++L++ + R RL Q++ DA + + ++ + M SE+ KDE +
Sbjct: 1439 LQQLWSRLRQEAELRHARLQEAHHAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVA 1498
Query: 2314 LLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPD---IRQRLDTTLKQKAELENLS 2484
+ KKH + ++++ + + L + L E HP+ I R K A L++LS
Sbjct: 1499 MQKKHQILEQAVEDYAETVHQLSKTSRGLVAEG--HPESERISMRQSQVDKLYASLKDLS 1556
Query: 2485 QLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDM 2664
+ R+ +L + L L++L + D +E WI E+ + + G+D E V +++ RF +D
Sbjct: 1557 EERRGKLDERLRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDT 1616
Query: 2665 KN-QEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRL 2841
+ +V VN LA +L+N H ++ + ++ LN WA L +++D + L + L
Sbjct: 1617 GTIGQERVDAVNRLADELINGGHGDAATVAEWKDGLNEAWADLLELIDTRTQILAASFEL 1676
Query: 2842 ETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHK 3021
F D +E + + DK + L + D D V LQR + E D+ A+ ++ L +
Sbjct: 1677 HKFYQDAKEILGRVVDKQKKLPEEDG--RDHHTVETLQRTHTAFEHDIQALGTQVRQLQE 1734
Query: 3022 EADDIERERP-QEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQA 3198
+A ++ +A+ I+ + + W L + +L + GD RF +
Sbjct: 1735 DAARLQSAYAGDKAEDIQRREGEVLEAWGALLQACERRRLRLLDTGDKFRFFSLVRDLML 1794
Query: 3199 WLTATQRQVASEEEPQSLAEAEQLLNQHAAIR----------EEIDGYAEDYKKMRAM-- 3342
W+ R + ++E P+ ++ E L+N H I + ED A+
Sbjct: 1795 WMEDVIRLIQAQEVPRDVSSVELLMNNHQGINGGDRRSQRQLHLLHRAGEDAAGQEALRL 1854
Query: 3343 ------GDRVTQDQTDPQYMFL-----RQRLAGLQEGWEELQRMWDNRQHLL-------S 3468
G R + ++ P +FL + RL L + +E+ W++R L S
Sbjct: 1855 GGGEGAGLRPGRGRSPPPTLFLLHPQIKDRLLQLTDKRKEMIDKWEDRWEWLRLSKPRPS 1914
Query: 3469 QGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIR 3648
+ + + QE YL+ ++ +S++Q E LKRH+ F + +E+
Sbjct: 1915 GPGGAPVLPGRGRGRGLAAGAQEPYLSSREVGRSVDQVEKLLKRHEAFEKSAATWEERFS 1974
Query: 3649 AV 3654
A+
Sbjct: 1975 AL 1976
Score = 81.3 bits (199), Expect = 3e-13
Identities = 45/108 (41%), Positives = 60/108 (54%), Gaps = 7/108 (6%)
Frame = +1
Query: 6418 RSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVLSLRL 6591
RSW +Y V+ E+SFYKD K + V H + P +L + +VASDY+KKK+V LRL
Sbjct: 2170 RSWHNVYCVINNGEMSFYKDGKAAAQGVAYHQQGPASLKDAACDVASDYKKKKHVFKLRL 2229
Query: 6592 PIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEAS-----RSQTLPA 6720
G EYLFQ EE+M W+ + A S R+QT+PA
Sbjct: 2230 ADGNEYLFQAKDEEEMSSWIQAVLTAASGGHGSPPSTPPPGRAQTMPA 2277
>gi|47221024|emb|CAG12718.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1673
Score = 1031 bits (2666), Expect = 0.0
Identities = 597/1664 (35%), Positives = 928/1664 (54%), Gaps = 5/1664 (0%)
Frame = +1
Query: 1237 FNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXX 1416
F+ K MR+ WL ENQRLVSQDNFG DL +VEAA KKHEAIE DI +YEER
Sbjct: 1 FDHKTTMRQAWLNENQRLVSQDNFGYDLPAVEAAMKKHEAIEADIASYEERIGVVVELSA 60
Query: 1417 XXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXX 1596
Y+D +I RKEN+ RR RLE ++++QKIF
Sbjct: 61 EMEAEAYYDIRRILARKENILGQWKLLKELVAGRRTRLEKNLSLQKIFQDMVYMIDWMED 120
Query: 1597 IKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYK 1776
+ +LLS+D G HL++VEDLLQKH+L E+DI + ERV + A +F G Y+
Sbjct: 121 TQVQLLSKDYGKHLLEVEDLLQKHSLQEADIAVQAERVESLNKAALKFTTIQG-----YQ 175
Query: 1777 PVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLS 1956
P +P I R + + +EL LA++R LE++++L F ++ E + I+E+ +L
Sbjct: 176 PCDPQVICNRVNHVSSCLEELKQLASKRCTDLEESRQLWAFLQELEESDAWIREKSSILG 235
Query: 1957 STDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEI 2136
+ G+D+ +V LL KHK L L GK++ E G+ I + E+
Sbjct: 236 AQGFGKDLTSVLKLLQKHKTLAGELLAHRSLLQNTIKQGKQILSEKSFGTTGIQEHILEL 295
Query: 2137 RDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLL 2316
++ +L++ + R L + ++QF T+ DD+ +L D R++SSED G DE + Q L
Sbjct: 296 KNQWKRLEDQAGQRLGHLQEALNFFQFSTEMDDLVAWLQDAYRLVSSEDFGHDEYSTQSL 355
Query: 2317 LKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRK 2496
LKKH + + ++ A+ E A P +R R+ EN + K
Sbjct: 356 LKKHAEFL---------VFLVFARLERRGNVA---PQLRARV--LHGDDVNTENPDE--K 399
Query: 2497 QRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQE 2676
+ +S Y +S ++ GK+L + E E + R++ L D+ +
Sbjct: 400 SIITYVVSYYHYFSKMKALIVEGKRVGKVLDNCI------EAEKIIDRYEALASDLLDWI 453
Query: 2677 AKVTNV---NDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLET 2847
K V A L V+ + + +W + ++V+QK+N+L RL+
Sbjct: 454 EKTIAVISNQKFANSLTGVQQQLQAFTTYCTIEKPIKWNSIVELVEQKKNQLNSMLRLQN 513
Query: 2848 FRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEA 3027
+ ++C E + I+DK + ++ + + +DL GVM LQRRLS ME L ++ KL L +EA
Sbjct: 514 YLLECVEIKSQIQDKRKAIDSTQYMGSDLGGVMALQRRLSTMEGALSVLEPKLLHLQEEA 573
Query: 3028 DDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLT 3207
+++ P A + I W+ L ++ E L A LQ F++DLD F WL
Sbjct: 574 ENLATAHPSRAMEVLVPFDDISVEWEELKHTLQGCEDSLMVASRLQSFIQDLDSFLTWLV 633
Query: 3208 ATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMF 3387
TQ AS++ P L EAE L+N+HAA++EEI Y EDY+++++M + + D+
Sbjct: 634 QTQTVAASDQLPNDLEEAETLINKHAALKEEIGRYEEDYERLQSMNELLDSDEAPLPQAA 693
Query: 3388 LRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQ 3567
L+Q L L GW +L MW++R+ +L Q +FLRD KQAE +L+ QE+ LA ++P
Sbjct: 694 LQQWLQKLDVGWNKLLEMWESRREVLVQAHIFHLFLRDVKQAESLLNNQESALAHVELPT 753
Query: 3568 SLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGA 3747
++E E +K+H+DF T+M+ N +I+AV G+ L + +++I ++ + R
Sbjct: 754 TVETVEAAIKKHKDFTTSMELNLHRIKAVIEAGESLISQNNIYSERIRERIDTLANRGNQ 813
Query: 3748 NREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAF 3927
NRE AQ+ L+KL LQ+FL +C EL +W+ EKM+ A+D + +++ + K+++HQAF
Sbjct: 814 NREMAQKWLEKLNHQWELQRFLQNCHELGDWVYEKMLMARDGSRDESQKLHKKWLKHQAF 873
Query: 3928 QSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDA 4107
+ELA NK+ LD+++ L +KPE + ++EE+ W +LE TT+ K ++LF+A
Sbjct: 874 MAELAQNKDWLDKIEKEGQQLMQEKPELSPVVRRKLEEIRDCWQDLESTTQAKARQLFEA 933
Query: 4108 NRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXX 4287
N+ L VQS + + QLE+++ DQ DLT VN ++K +E +M + +
Sbjct: 934 NKADLVVQSYESLDQRLNQLEDQLAYVDQGQDLTGVNNQLKKLQTMENQMEDWYKEV-GL 992
Query: 4288 XXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEK 4467
E + + AV+ ++ RL PL +RR+ L K Q RD++DE
Sbjct: 993 LQVQAATIPQQTQRNETVSERQTAVEARMVRLIEPLKERRRILLASKELHQVRRDLEDEI 1052
Query: 4468 LWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHAN 4647
LWI ERL +A +Q G +L + +L K Q+L E+ H+ I + +
Sbjct: 1053 LWIQERLPMAMSQEHGSTLQEVQQLMKKNQMLQRELQGHKGRIEDVLERAGIIASIRSPE 1112
Query: 4648 GPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDE 4827
+ +L W L + R+ L +A Q+ +D E EAW+SEQEL+MM +E
Sbjct: 1113 ADSVRTGHDQLAQLWNLLWVETERRQLVLDAMYQAQQYFFDTAEVEAWLSEQELHMMNEE 1172
Query: 4828 RGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKL 5007
+GKDE ST +KKH L+ I+ +A+TI L+ + + +E P E I RQ+QI++L
Sbjct: 1173 KGKDEPSTLQLLKKHLVLEQTIEDYAETIGLLSQQCRQLLEMGHPDCEHISRRQSQIDRL 1232
Query: 5008 YAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQER 5187
Y L+D Y L+RE+D+L QWIA KEVVA S E GQD+EHV +LQ++
Sbjct: 1233 YVSLKDLVEERKSRLEQQYWLYQLNREVDELEQWIAQKEVVASSPELGQDFEHVTVLQDK 1292
Query: 5188 FQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQ 5367
F +FA +T ++G ERV N D LI +GH++A TIA WKD +NEAW +LLELM+TR+Q
Sbjct: 1293 FTKFATETGSVGQERVTAVNQMVDELIDYGHSEAATIAEWKDGVNEAWADLLELMETRSQ 1352
Query: 5368 ILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGR--DSSSVGALSRKHQNYLKDIAAIG 5541
+L AS LHKF+ DCR+ L++I +K +P+ + +S++ L R ++ +DI +
Sbjct: 1353 MLAASHQLHKFFSDCREILAQIDDKHRRLPEVRAKQGNSANTNTLKRLLHSFEQDIQLLV 1412
Query: 5542 EQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFM 5721
QV ++ AA+LR YAG+KA I E EV+++W+ L C+ + +D KF+
Sbjct: 1413 TQVRHLQESAAQLRTVYAGEKAEAIACCEHEVMQSWKELLTSCEECRVEITTETDKLKFL 1472
Query: 5722 NMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDL 5901
MVRD L+WMD + ++ + E+P+DVS VE+LMN HQSLK+E++AR + CI +G+ L
Sbjct: 1473 GMVRDQLIWMDSIICQIGTGEKPRDVSSVEVLMNYHQSLKSEVEARSRSTLECIEMGKTL 1532
Query: 5902 LNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQE 6081
L ++ A+ EI++KL K+ ++ E+ +W+ WE LQ +LEV+QFA++A VAE+WL AQE
Sbjct: 1533 LAVRNPAAEEIKEKLEKVVAKQHELSEKWDKHWEVLQQLLEVHQFAQEAVVAEAWLTAQE 1592
Query: 6082 PYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
P + S G +++E +LI++HEAF K+A EERF +L +LTT
Sbjct: 1593 PLVNSSLLGESVDEVEQLIRRHEAFRKAAATWEERFSSLRRLTT 1636
Score = 239 bits (610), Expect = 7e-61
Identities = 254/1226 (20%), Positives = 504/1226 (40%), Gaps = 69/1226 (5%)
Frame = +1
Query: 700 AKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRY 879
A+ L +DVN + PDEKSIITYVV+YYHYF+K+K ++GKR+GKV++ +E +K+I+RY
Sbjct: 383 ARVLHGDDVNTENPDEKSIITYVVSYYHYFSKMKALIVEGKRVGKVLDNCIEAEKIIDRY 442
Query: 880 ETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGEL-EVLL 1056
E L+SDLL+WI I +++ + F N+L GVQ+QL F Y T EKP K++ EL E
Sbjct: 443 EALASDLLDWIEKTIAVISNQKFANSLTGVQQQLQAFTTYCTIEKPIKWNSIVELVEQKK 502
Query: 1057 FTLQSAMRANN-----------------------------------QRPFVPREGKL--- 1122
L S +R N QR EG L
Sbjct: 503 NQLNSMLRLQNYLLECVEIKSQIQDKRKAIDSTQYMGSDLGGVMALQRRLSTMEGALSVL 562
Query: 1123 ---IADINRAWQSLEKAEHEREL--------------VLKEELIRQEKLEQLAAR---FN 1242
+ + ++L A R + LK L E +A+R F
Sbjct: 563 EPKLLHLQEEAENLATAHPSRAMEVLVPFDDISVEWEELKHTLQGCEDSLMVASRLQSFI 622
Query: 1243 RKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXX 1422
+ + TWL + Q + + D NDL E KH A++ +I YEE
Sbjct: 623 QDLDSFLTWLVQTQTVAASDQLPNDLEEAETLINKHAALKEEIGRYEEDYERLQSMNELL 682
Query: 1423 XXXNYH-DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXI 1599
QA + + + + +RR L +
Sbjct: 683 DSDEAPLPQAALQQWLQKLDVGWNKLLEMWESRREVLVQAHIFHLFLRDVKQAESLLNNQ 742
Query: 1600 KSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKP 1779
+S L +L + VE ++KH + + + R+ I + + +
Sbjct: 743 ESALAHVELPTTVETVEAAIKKHKDFTTSMELNLHRIKAVIEAGESLISQNN-------- 794
Query: 1780 VEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSS 1959
+ I ER D L R + ++A + +L L +F + EL G E++L +
Sbjct: 795 IYSERIRERIDTLANRGNQNREMAQKWLEKLNHQWELQRFLQNCHEL--GDWVYEKMLMA 852
Query: 1960 TDTGRDIVTVSH-LLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEI 2136
D RD H KH+ L + +LD+++ G++L E S + +L EI
Sbjct: 853 RDGSRDESQKLHKKWLKHQAFMAELAQNKDWLDKIEKEGQQLMQEKPELSPVVRRKLEEI 912
Query: 2137 RDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLL 2316
RD L+ + ++ +L + + +D+ L ++ D G+D V
Sbjct: 913 RDCWQDLESTTQAKARQLFEANKADLVVQSYESLDQRLNQLEDQLAYVDQGQDLTGVNNQ 972
Query: 2317 LKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRK 2496
LKK + ++++++ + + +L +A ++PQ+ + + + +R + L + R+
Sbjct: 973 LKKLQTMENQMEDWYKEVGLLQVQAATIPQQTQRNETVSERQTAVEARMVRLIEPLKERR 1032
Query: 2497 QRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQE 2676
+ L+ + L+++ D + WI E+ + + G ++EV+ + + L+++++ +
Sbjct: 1033 RILLASKELHQVRRDLEDEILWIQERLPMAMSQEHGSTLQEVQQLMKKNQMLQRELQGHK 1092
Query: 2677 AKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRI 2856
++ +V + A + ++ P +D + ++L W L ++++ L+ ++ + +
Sbjct: 1093 GRIEDVLERAGIIASIRSPEADSVRTGHDQLAQLWNLLWVETERRQLVLDAMYQAQQYFF 1152
Query: 2857 DCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDI 3036
D E W+ ++ + + + ++ S + L++ L ++E+ + + L ++ +
Sbjct: 1153 DTAEVEAWLSEQELHMMNEEKGKDEPSTLQLLKKHL-VLEQTIEDYAETIGLLSQQCRQL 1211
Query: 3037 ERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQ 3216
+ + I +I +++ L V E +++L++ L + R++D + W+ +
Sbjct: 1212 LEMGHPDCEHISRRQSQIDRLYVSLKDLVEERKSRLEQQYWLYQLNREVDELEQWIAQKE 1271
Query: 3217 RQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQ--DQTDPQYMFL 3390
+S E Q L ++ E ++ ++ A+ V + D + +
Sbjct: 1272 VVASSPELGQDFEHVTVLQDKFTKFATETGSVGQE--RVTAVNQMVDELIDYGHSEAATI 1329
Query: 3391 RQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQS 3570
+ G+ E W +L + + R +L+ L F D ++ + + L + Q
Sbjct: 1330 AEWKDGVNEAWADLLELMETRSQMLAASHQLHKFFSDCREILAQIDDKHRRLPEVRAKQG 1389
Query: 3571 LEQAENQLKR-HQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGA 3747
N LKR F + ++R + QL YA +K A E +
Sbjct: 1390 NSANTNTLKRLLHSFEQDIQLLVTQVRHLQESAAQL--RTVYAGEKAEAIACCEHEVMQS 1447
Query: 3748 NRE---KAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIR-AQDETYRDAKTITSKFVR 3915
+E +E ++ +FL + W++ + + E RD ++
Sbjct: 1448 WKELLTSCEECRVEITTETDKLKFLGMVRDQLIWMDSIICQIGTGEKPRDVSSVEVLMNY 1507
Query: 3916 HQAFQSEL-AANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQ 4092
HQ+ +SE+ A ++ L+ ++ L P I ++E++ + EL + ++ +
Sbjct: 1508 HQSLKSEVEARSRSTLECIEMGKTLLAVRNPAAE-EIKEKLEKVVAKQHELSEKWDKHWE 1566
Query: 4093 KLFDANRQQLYVQSIADMKEWATQLE 4170
L + Q + W T E
Sbjct: 1567 VLQQLLEVHQFAQEAVVAEAWLTAQE 1592
Score = 143 bits (361), Expect = 5e-32
Identities = 263/1469 (17%), Positives = 533/1469 (35%), Gaps = 36/1469 (2%)
Frame = +1
Query: 907 WINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRAN 1086
WI K +L + F +L V + L + GEL LQ+ ++
Sbjct: 226 WIREKSSILGAQGFGKDLTSVLKLLQKHKTLA-----------GELLAHRSLLQNTIKQG 274
Query: 1087 NQRPFVPREGKL-----IADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKA 1251
Q G I ++ W+ LE +R L+E L +F+ +
Sbjct: 275 KQILSEKSFGTTGIQEHILELKNQWKRLEDQAGQRLGHLQEALN--------FFQFSTEM 326
Query: 1252 EMRETWLTENQRLVSQDNFGNDLSSVEAATKKH-EAIETDIFAYEERXXXXXXXXXXXXX 1428
+ WL + RLVS ++FG+D S ++ KKH E + +FA ER
Sbjct: 327 DDLVAWLQDAYRLVSSEDFGHDEYSTQSLLKKHAEFLVFLVFARLERRGNVAPQLRARVL 386
Query: 1429 XNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSR 1608
D N ++++ + + + K+ I++
Sbjct: 387 HG-DDVNTENPDEKSIITYVVSYYHYFSKMKALIVEGKRVGKVL---------DNCIEAE 436
Query: 1609 LLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEP 1788
+ + A D+ D ++K + I ++ NS+ Q+ + KP++
Sbjct: 437 KIIDRYEALASDLLDWIEKTIAV-----ISNQKFANSLTGVQQQLQAFTTYCTIEKPIKW 491
Query: 1789 GTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTD- 1965
+I ++L ++K +L RL + + E++ I+++ + + ST
Sbjct: 492 NSI--------------VELVEQKKNQLNSMLRLQNYLLECVEIKSQIQDKRKAIDSTQY 537
Query: 1966 TGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDY 2145
G D+ V L + E L LE L L + L + + +I
Sbjct: 538 MGSDLGGVMALQRRLSTMEGALSVLEPKLLHLQEEAENLATAHPSRAMEVLVPFDDISVE 597
Query: 2146 INKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKK 2325
+LK ++ L F D D +L T V +S+ + D + L+ K
Sbjct: 598 WEELKHTLQGCEDSLMVASRLQSFIQDLDSFLTWLVQTQTVAASDQLPNDLEEAETLINK 657
Query: 2326 HDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIR-----QRLDTTLKQKAELENLSQL 2490
H + +E+ +++ + L + E L + P Q+LD + E + +
Sbjct: 658 HAALKEEIGRYEEDYERLQSMNELLDSDEAPLPQAALQQWLQKLDVGWNKLLE---MWES 714
Query: 2491 RKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVE--IMKHRFDTLEQDM 2664
R++ L+ A + D ES ++ + LA + +E VE I KH+ T ++
Sbjct: 715 RREVLVQAHIFHLFLRDVKQAESLLNNQESALAHVELPTTVETVEAAIKKHKDFTTSMEL 774
Query: 2665 KNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLE 2844
K V + L++ + S+ I R + L R Q R+M + +L L+
Sbjct: 775 NLHRIKA--VIEAGESLISQNNIYSERIRERIDTLANRGNQNREMAQKWLEKLNHQWELQ 832
Query: 2845 TFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKE 3024
F +C E W+ +K + D + L+ + M E L + LD + KE
Sbjct: 833 RFLQNCHELGDWVYEKMLMARDGSRDESQKLHKKWLKHQAFMAE--LAQNKDWLDKIEKE 890
Query: 3025 ADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWL 3204
+ +E+P+ + +R ++ I W L + +L EA ++ + L
Sbjct: 891 GQQLMQEKPELSPVVRRKLEEIRDCWQDLESTTQAKARQLFEANKADLVVQSYESLDQRL 950
Query: 3205 TATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYM 3384
+ Q+A ++ Q L L + + +++ + ++ ++ + Q + +
Sbjct: 951 NQLEDQLAYVDQGQDLTGVNNQLKKLQTMENQMEDWYKEVGLLQVQAATIPQQTQRNETV 1010
Query: 3385 FLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIP 3564
RQ ++ L R+ +L L RD + + + ++ +
Sbjct: 1011 SERQ--TAVEARMVRLIEPLKERRRILLASKELHQVRRDLEDEILWIQERLPMAMSQEHG 1068
Query: 3565 QSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKI---HKKARNIDE 3735
+L++ + +K++Q + + +I V + AD + H + +
Sbjct: 1069 STLQEVQQLMKKNQMLQRELQGHKGRIEDVLERAGIIASIRSPEADSVRTGHDQLAQLWN 1128
Query: 3736 RRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITSKFV 3912
E+ Q VL + A QQ+ D E+ W+ E+++ +E +D +
Sbjct: 1129 LLWVETERRQLVLDAMYQA---QQYFFDTAEVEAWLSEQELHMMNEEKGKDEPSTLQLLK 1185
Query: 3913 RHQAFQSELAANKER---LDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDEL---EKT 4074
+H + + E L Q + +G E+ QI+ L +L K+
Sbjct: 1186 KHLVLEQTIEDYAETIGLLSQQCRQLLEMGHPDCEHISRRQSQIDRLYVSLKDLVEERKS 1245
Query: 4075 TEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETE 4254
E+ L+ NR+ + ++++W Q E + + D V V K TE
Sbjct: 1246 RLEQQYWLYQLNRE------VDELEQWIAQKEVVASSPELGQDFEHVTVLQDKFTKFATE 1299
Query: 4255 MIKKAQ-HIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
Q + E I + V E L ++ R + L
Sbjct: 1300 TGSVGQERVTAVNQMVDELIDYGHSEAATIAEWKDGVNEAWADLLELMETRSQMLAASHQ 1359
Query: 4432 AFQFGRD-------VDDEKLWISE-RLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHE 4587
+F D +DD+ + E R + N H ++++QLL ++ + +
Sbjct: 1360 LHKFFSDCREILAQIDDKHRRLPEVRAKQGNSANTNTLKRLLHSFEQDIQLLVTQVRHLQ 1419
Query: 4588 PWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLY 4767
Q+ + G A E+ +W+EL + ++ + ++ +FL
Sbjct: 1420 ESAAQL-----RTVYAGE-KAEAIACCEHEVMQSWKELLTSCEECRVEITTETDKLKFLG 1473
Query: 4768 DCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFV 4947
+ WM + E+ +D S + + H+ L+S+++ + + +
Sbjct: 1474 MVRDQLIWMDSIICQIGTGEKPRDVSSVEVLMNYHQSLKSEVEARSRSTLECIEMGKTLL 1533
Query: 4948 EEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLL---QWIAD 5118
++P E+I + ++EK+ A + +H+ + + W+
Sbjct: 1534 AVRNPAAEEI---KEKLEKVVAKQHELSEKWDKHWEVLQQLLEVHQFAQEAVVAEAWLTA 1590
Query: 5119 KEVVAGSQENGQDYEHVQMLQERFQQFAR 5205
+E + S G+ + V+ L R + F +
Sbjct: 1591 QEPLVNSSLLGESVDEVEQLIRRHEAFRK 1619
Score = 46.2 bits (108), Expect = 0.011
Identities = 80/410 (19%), Positives = 152/410 (36%), Gaps = 8/410 (1%)
Frame = +1
Query: 1126 ADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDN 1305
+ I+R + SL+ ER K L +Q L QL NR+ + E W+ + + + S
Sbjct: 1227 SQIDRLYVSLKDLVEER----KSRLEQQYWLYQL----NREVDELEQWIAQKEVVASSPE 1278
Query: 1306 FGNDLSSVEAATKKHEAIETDIFAY-EERXXXXXXXXXXXXXXNYHDQAKINERKENVXX 1482
G D V K T+ + +ER + + A I E K+ V
Sbjct: 1279 LGQDFEHVTVLQDKFTKFATETGSVGQERVTAVNQMVDELIDYGHSEAATIAEWKDGVNE 1338
Query: 1483 XXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRL----LSEDLGAHLMDVE 1650
R L S + K F RL + A+ ++
Sbjct: 1339 AWADLLELMETRSQMLAASHQLHKFFSDCREILAQIDDKHRRLPEVRAKQGNSANTNTLK 1398
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
LL E DI ++ +V + A + R + Y + I + + +
Sbjct: 1399 RLLHS---FEQDIQLLVTQVRHLQESAAQLR-------TVYAGEKAEAIACCEHEVMQSW 1448
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG---RDIVTVSHLL 2001
KELL E + + +F + + + + ++ TG RD+ +V L+
Sbjct: 1449 KELLTSCEECRVEITTETDKLKF---LGMVRDQLIWMDSIICQIGTGEKPRDVSSVEVLM 1505
Query: 2002 AKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRK 2181
H++ ++ + + GK L P ++ I +L ++ ++L E
Sbjct: 1506 NYHQSLKSEVEARSRSTLECIEMGKTLLAVRNPAAEEIKEKLEKVVAKQHELSEKWDKHW 1565
Query: 2182 ERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHD 2331
E L +E +QF +A + +L +++S +G+ V+ L+++H+
Sbjct: 1566 EVLQQLLEVHQFAQEAVVAEAWLTAQEPLVNSSLLGESVDEVEQLIRRHE 1615
Score = 38.9 bits (89), Expect = 1.8
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 11/140 (7%)
Frame = +1
Query: 1003 TQEKPPKFDEKGELEVLLF---TLQSAMRANNQRPFVPRE-GKLIADINRAWQSLEKAEH 1170
T EKP + +EVL+ +L+S + A ++ E GK + + K +
Sbjct: 1491 TGEKPR---DVSSVEVLMNYHQSLKSEVEARSRSTLECIEMGKTLLAVRNPAAEEIKEKL 1547
Query: 1171 ERELVLKEELIRQ-----EKLEQLAA--RFNRKAEMRETWLTENQRLVSQDNFGNDLSSV 1329
E+ + + EL + E L+QL +F ++A + E WLT + LV+ G + V
Sbjct: 1548 EKVVAKQHELSEKWDKHWEVLQQLLEVHQFAQEAVVAEAWLTAQEPLVNSSLLGESVDEV 1607
Query: 1330 EAATKKHEAIETDIFAYEER 1389
E ++HEA +EER
Sbjct: 1608 EQLIRRHEAFRKAAATWEER 1627
>gi|24656802|ref|NP_523900.1| CG12008-PA [Drosophila melanogaster]
gi|7292359|gb|AAF47766.1| CG12008-PA [Drosophila melanogaster]
Length = 4097
Score = 989 bits (2558), Expect = 0.0
Identities = 654/2211 (29%), Positives = 1074/2211 (47%), Gaps = 168/2211 (7%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGER 255
FE RIK L +ER +QKKTFTKW+NS L++ +V+DL+ D+ DG LL+LL ++S E+
Sbjct: 10 FENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEK 69
Query: 256 LPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQI 435
L KP G+MR+H +ENV K L FL + V LE++G+ DIVDGN RL LGLIWTIILRFQI
Sbjct: 70 LGKPNSGRMRVHKIENVNKSLAFLHTK-VRLESIGAEDIVDGNPRLILGLIWTIILRFQI 128
Query: 436 QDITF---EDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHR 606
Q+I E+ ++ E RSAK+ALLLWCQ KT GYP VN+ +F+ SWR GL FNALIH HR
Sbjct: 129 QEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHR 188
Query: 607 PDLVDYDNL--QKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
PDL +Y + K++ L NL AFDTA N+LG+ LDAED++ +PDEKSI+TYV +YY
Sbjct: 189 PDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYY 248
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
H F ++K + GKRI ++ +LM+ D+ +YE L+++LL WI K L +R N+L
Sbjct: 249 HTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSL 308
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
EG+QR+L F +YRT EKPPK+ E+ E+E L FT+ + ++A NQ P+ P++G+L+ DI +
Sbjct: 309 EGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEK 368
Query: 1141 AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDL 1320
AWQ LE AEH RE+ L++EL+RQEKLEQL +F +K+ +RE +L E +++S + L
Sbjct: 369 AWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRY---L 425
Query: 1321 SSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXX 1500
V+A KKHEAI DI A ER NYH + ++ R++ V
Sbjct: 426 RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLL 485
Query: 1501 XXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLE 1680
+R+ L + + ++ + SED+G HL+ VE+LLQ H+L E
Sbjct: 486 ELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQE 545
Query: 1681 SDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAER 1860
+N GE + QA +++ + D + + +R L++ Y ELL +A R
Sbjct: 546 LQVNTYGETLKRFNRQALPYKSSEHKDAA--------LLAQRLADLEEAYSELLRRSAAR 597
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
+ RLE+ + F D E + +++++ + T +D+ V L KHK E+ ++
Sbjct: 598 RARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSR 657
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
+ ++ +GK L E P S I R+ + ++ L+ L R+ +L E YQF+
Sbjct: 658 KPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFY 717
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
TDA++ + +L + + +++S D G DE + Q LL++H D+ EL + I L+ +A+ L
Sbjct: 718 TDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKL 777
Query: 2401 PQEA----------REHPDIRQR---LDTTLKQK--------AELENLSQLRKQRLIDAL 2517
+ E P++ Q +T L K +LE+ + L
Sbjct: 778 IKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVK 837
Query: 2518 SLY--------------KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLE 2655
SL+ L + + W K + VP + EVE +
Sbjct: 838 SLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPK 897
Query: 2656 QDMKNQEAKVTNVNDLARQLLNVE----------------------HPNSDDILHRQNKL 2769
+ KV L RQ++ V+ + N+D + RQ ++
Sbjct: 898 AEKVKSLQKVKK-TILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRI 956
Query: 2770 NARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMK 2949
N + +L++M ++ LE + L F +C + W+++K R+++ + GV
Sbjct: 957 NQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEG-----EGVDN 1011
Query: 2950 LQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVRE 3129
+R+ DL A +++ + D R+ + I ++IHQ+W LN +
Sbjct: 1012 AKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQ 1071
Query: 3130 HEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E L+ A ++ F R D + W++ Q+ + L + L +H + E+
Sbjct: 1072 REKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAP 1131
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQM 3489
+ ++ +G+ V ++ + + R +Q+ W+++Q+ + ++ + + Q+
Sbjct: 1132 VEDKVNRVTYLGNSV-KNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQV 1190
Query: 3490 FLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGD 3669
F AK + ++ L D+ + +E A N LK+H D + A+D + V G
Sbjct: 1191 FNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGK 1250
Query: 3670 QLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL------ 3831
QL A+ + R E+ +R A E K L + LQ F + D++
Sbjct: 1251 QLSDGKPNMAETVAVIERLKAEQDAIHRGWA-EKQKWLLQCVDLQMFNREADKIDATTKS 1309
Query: 3832 ----------------------REWIEEKMIRAQDETYR---------------DAKTI- 3897
R EK + AQD+ + D+K I
Sbjct: 1310 HEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIG 1369
Query: 3898 --------TSKFVRHQAFQSE--LAANKE------RLDQLK----HAAINLGDDKPEYHG 4017
K V+ +AF+ + L A+K+ D LK GD+
Sbjct: 1370 DRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLS 1429
Query: 4018 TIDPQIE-------ELATQWDELEKTTEEKGQKLFDANRQQLYVQS-IADM-KEW----- 4155
+ +++ EL +L T++ GQ L A + V+S +AD+ K W
Sbjct: 1430 NLPRKLQKHQAFERELRANEGQLRNVTKD-GQALVQAGNRVPEVESRVADLNKRWKDLLT 1488
Query: 4156 ------------ATQLENEMTREDQP----------------GDLTTVNVAMQKQHLIET 4251
A+Q E+ + ED DL + + KQ ++E+
Sbjct: 1489 LSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILES 1548
Query: 4252 EMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
E+ Q + +NI+A +Q++ + L+ P RR LE
Sbjct: 1549 EITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLN 1608
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
+F ++D E WI+E L AK+ LG++L L K + L EI H+P IN+
Sbjct: 1609 YHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALV 1668
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
GQ LI + H E Q+L AWQ+L+ +R L S KA Q+L+D GE E+W
Sbjct: 1669 AGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESW 1728
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+ E+ + E G+D S + KH+ ++ ++D ++ + + V P ++
Sbjct: 1729 LGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSK 1788
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENG 5151
+ +Q IEK+ L + E D++ QWI ++E A S++ G
Sbjct: 1789 VLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYG 1848
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
QD+EH+Q+LQ +F E +G++RV LI A + ++ L +W
Sbjct: 1849 QDFEHLQLLQNKFDDLKHRVE-VGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSW 1907
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQ 5511
ENLL+L++ R Q L A+ +H+F+ D + L RI +K A+ +LGRD +S AL RKH+
Sbjct: 1908 ENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHE 1967
Query: 5512 NYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRL 5691
+ D+ A+ Q+ + D+ L+ Y + A I ++ +VV AW L+ AR RL
Sbjct: 1968 GFENDLVALEAQLQVLVEDSVRLQAKYPSN-ASAIAQQQDKVVAAWNDLKERSTARGDRL 2026
Query: 5692 MDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENF 5871
+SDL F+ VRD++ W ++ + ++E D +G L H ++ EI+ARE+ F
Sbjct: 2027 AASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKF 2086
Query: 5872 NACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAA 6051
L ++ HYA++++E+K + ER ++ W + L+ ++++ F RDA
Sbjct: 2087 RYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAK 2146
Query: 6052 VAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
++ +Q+ L S ++G+ +E+ I+KH+ FE+ QEE+ L++
Sbjct: 2147 QIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQE 2197
Score = 575 bits (1481), Expect = e-162
Identities = 437/1831 (23%), Positives = 827/1831 (44%), Gaps = 18/1831 (0%)
Frame = +1
Query: 811 IQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEF 990
+ +R G+++ L +++ + S ++ +WI + Q + + + E +Q +F
Sbjct: 1807 LASQRQGRLMESLYKHEYFLE-----SDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKF 1861
Query: 991 NDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEH 1170
+D + + + D + E+L L +++ P+ K + +W++L + +
Sbjct: 1862 DDLKHRVEVGA-DRVDQCELLAKKL-----IDSESPYANEVEKRQEQLRTSWENLLQLLN 1915
Query: 1171 ERELVLKEELIRQEKLEQLAA--RFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATK 1344
+RE +KL RF+R + + +SQ+ G DL+S A +
Sbjct: 1916 QRE----------QKLHAAGEIHRFHRDVAEALFRIQDKNAALSQE-LGRDLNSALALLR 1964
Query: 1345 KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRV 1524
KHE E D+ A E + + + I ++++ V AR
Sbjct: 1965 KHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGD 2024
Query: 1525 RLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE 1704
RL S +Q +++ L +E+ + L +H + +I +
Sbjct: 2025 RLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEARED 2084
Query: 1705 R------VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKR 1866
+ +++S+ Q + D ++E+ + ++L ++K
Sbjct: 2085 KFRYLNELSDSMVQTGHYAAAD--------------VEEKCAAMLDERQKLHAAWNKKKI 2130
Query: 1867 RLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEK 2046
LE L F D ++++ Q+ LSS+D G+ + V + + KH E ++ E+
Sbjct: 2131 MLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEE 2190
Query: 2047 YLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTD 2226
+ L G++L ++ S NI L + K+K+L A R+ +L + Y +F D
Sbjct: 2191 KVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRD 2250
Query: 2227 ADDVDRYLYDTLRVMSSEDVGKDEGTVQ----LLLKKHDDVHDELQNFDQHIKVLHAKAE 2394
+ ++ + + + ++ E T L+KH E+ I+ +
Sbjct: 2251 CAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGV 2310
Query: 2395 SLPQEAREH-PDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDE 2571
L + E P+I++ ++ L+ L + R + L +A + S D +E+WI +
Sbjct: 2311 ILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRD 2370
Query: 2572 KGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSD--D 2745
K ++ GRD+E + + D ++ DM+ + +V ++N LA +L+N +D
Sbjct: 2371 KEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQS 2430
Query: 2746 ILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALT 2925
+ R+ N W QL+ ++ R L A+ + F D +T I +K+ + +D
Sbjct: 2431 VDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDT-G 2489
Query: 2926 NDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQE-AQAIREDIKRIHQVW 3102
DL+ V L RR +ERD+ A++ K+D A+ + ++ P+ AQ I ++ +H+ W
Sbjct: 2490 RDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSW 2549
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
L + ++ L+EA +F+ D+ + W+ +++ + + P ++ + E L H
Sbjct: 2550 GNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELH 2609
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHL 3462
+ EI+G E + ++ G+++++ Q +R+ L L+E + L W R
Sbjct: 2610 QERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARD 2669
Query: 3463 LSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEK 3642
L++ LQ+F +Q E+ L+ +E +L DD+ S E LK+H +F + A +
Sbjct: 2670 LTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHA--DH 2727
Query: 3643 IRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDC 3822
+ + F + + + AD I +K I R+ E ++E ++L + LQ+FL
Sbjct: 2728 VDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSL 2787
Query: 3823 DELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDK 4002
E+ W+ +K+ A DE YR+ + SK +H AF +EL +N R+ + H L
Sbjct: 2788 YEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGD 2847
Query: 4003 PEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMT 4182
I Q++ L W +L+ ++ K KL A + +S+ + W ++E +++
Sbjct: 2848 HFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLS 2907
Query: 4183 REDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAV 4362
ED DL V+ ++K +E ++ + D I
Sbjct: 2908 SEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVS 2967
Query: 4363 QEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRL 4542
+ L PL RR+ LE + QF RD +DE W++E+ ++A +Q+LG SL L
Sbjct: 2968 IRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGL 3027
Query: 4543 QKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDR 4722
QK L E+ + EP I + GQ++I + H + K + L+ +L++ R
Sbjct: 3028 QKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIR 3087
Query: 4723 KGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKF 4902
+ L ++ ++ F + EA+AWM E+ + + G+DE S + KK E LQ ++ F
Sbjct: 3088 RLRLLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAF 3147
Query: 4903 ADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALH 5082
+I +A A +E + I + AQ+ + Y L +
Sbjct: 3148 KPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYL 3207
Query: 5083 REIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDT 5262
RE ++L +W+ D+ V S++ G+D EHV+ L F+ F + N RV + D
Sbjct: 3208 RETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNL-NANEARVEACLERGDR 3266
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
LI + +I +D + WE L +L+ R L ++ +H + + + I EK
Sbjct: 3267 LIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEK 3326
Query: 5443 THAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
++ +D G+D S+ AL RKHQ + ++ I QV + +AA+L + Y K I
Sbjct: 3327 DASLISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKE-HIE 3385
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
+ E V+AW L+ AR ++L L + + RDL+ W++E+ ++ + E V
Sbjct: 3386 VKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSV 3445
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
+G ELL+ + + EI R+E F + G+ L+ KH+ + E+E K IK+ R E++
Sbjct: 3446 AGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDK-IKVLQARHELL 3504
Query: 5980 RRW-EDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+ R E +L L+ F +DA + E W+ ++EP L + G ++ + L+++HE F
Sbjct: 3505 KHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDF 3564
Query: 6157 EKSAFAQEERFLALEKLTTFELKETQHREEE 6249
EK+ AQEE+F A++++T E E+E
Sbjct: 3565 EKTVAAQEEKFQAIKRITMLEQLFRHQLEQE 3595
Score = 392 bits (1006), Expect = e-107
Identities = 348/1705 (20%), Positives = 705/1705 (40%), Gaps = 23/1705 (1%)
Frame = +1
Query: 1117 KLIA---DINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQR 1287
K+IA I++ WQ L A+ +RE L+ FNR + + W++E
Sbjct: 1050 KIIARQRQIHQIWQRLNNAKAQREKSLEGA--------SSVELFNRTCDEAKVWMSEKML 1101
Query: 1288 LVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERK 1467
+ DL +V+A ++H+ +E ++ E++ ++ +N R+
Sbjct: 1102 QLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQ 1161
Query: 1468 ENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDV 1647
+ V R R+E + Q + +K +L +++ +
Sbjct: 1162 QEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETA 1221
Query: 1648 EDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKR 1827
+LL+KH L DI I ++ DG + D + +
Sbjct: 1222 NNLLKKHNDLGDDIRAHDTEFVEVIQLGKQL--SDGKPNMAETVAVIERLKAEQDAIHRG 1279
Query: 1828 YKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAK 2007
+ AE+++ L L F + +++ K E L + G + V +L +
Sbjct: 1280 W-------AEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKR 1332
Query: 2008 HKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKER 2187
H + E +L +K L + +L S I R ++ +K+ + RK
Sbjct: 1333 HLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRL 1392
Query: 2188 LAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQH 2367
L ++++F +ADD+ +L D R+ E+ +D + L+KH EL+ +
Sbjct: 1393 LQASKDFHKFAAEADDLKVWLQDKTRIAGDENY-RDLSNLPRKLQKHQAFERELRANEGQ 1451
Query: 2368 IKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDAD 2547
++ + ++L Q P++ R+ K+ +L LS+ + ++L A S + +
Sbjct: 1452 LRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLE 1511
Query: 2548 SVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE 2727
+ +DE L + G D+ + + ++ LE ++ + KV + + +
Sbjct: 1512 DAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGG 1571
Query: 2728 HPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
H N+ +I +L R+ LRD ++R +LE + F + WI + +
Sbjct: 1572 HFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAK 1631
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKR 3087
S+ L +L L ++ +E ++ Q ++ + ++ E + + ++
Sbjct: 1632 -SNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQ 1690
Query: 3088 IHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQ 3267
+ Q W L + E KLD + Q++L D ++WL + S E + A +
Sbjct: 1691 LEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAK 1750
Query: 3268 LLNQHAAIREEIDGYAEDYKKM-RAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMW 3444
LL +H I E+D Y+ +M + V + D + + +Q+L +++ + L ++
Sbjct: 1751 LLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQL--IEKMLKSLHKLA 1808
Query: 3445 DNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTM 3624
RQ L + L + ++ + E + +QE + +D Q E + + D +
Sbjct: 1809 SQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRV 1868
Query: 3625 DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQ 3804
+ +++ + +L A+++ K+ + + + +KL A +
Sbjct: 1869 EVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIH 1928
Query: 3805 QFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAI 3984
+F D E I++K E RD + + +H+ F+++L A + +L L ++
Sbjct: 1929 RFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSV 1988
Query: 3985 NLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ 4164
L P I Q +++ W++L++ + +G +L ++ Q ++ + D+ W++
Sbjct: 1989 RLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSN 2048
Query: 4165 LENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIK 4344
L + E+ D + I E+ + +++
Sbjct: 2049 LRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVE 2108
Query: 4345 AHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESL 4524
A+ ++ Q+L A + ++ LE+K F F RD S + + + G+++
Sbjct: 2109 EKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTV 2168
Query: 4525 PDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELK 4704
D + I E ++ + +G++LI++ H + + +Q + + Q++K
Sbjct: 2169 EDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVK 2228
Query: 4705 EAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ----IKKH 4872
+ R+ L ++ +F+ DC EA+ W++E++ + D E + ++ ++KH
Sbjct: 2229 DLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKH 2288
Query: 4873 ERLQSD-------IDKFADTIRALATKAHKFVEEKSPLTEQI----QVRQAQIEKLYAGL 5019
+ Q++ I + DT L +K H+ E E + Q A++E+ GL
Sbjct: 2289 QAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGL 2348
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQF 5199
++ + ++D + WI DKE++ + + G+D EH L +
Sbjct: 2349 EE-----------AQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDV 2397
Query: 5200 ARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWK--DSLNEAWENLLELMDTRAQIL 5373
D + +RV + N D LI A T ++ K N W L ++ +L
Sbjct: 2398 DSDM-RVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALL 2456
Query: 5374 EASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQV 5550
+ +H F D D RI EK+ AM D GRD ++V AL R+ + +D++A+ +++
Sbjct: 2457 GGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKI 2516
Query: 5551 AQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMV 5730
Q E A L Y A I + E+ K+W +L+ L R S L + KF++ V
Sbjct: 2517 DQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDV 2576
Query: 5731 RDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR 5910
++L LW++++ ++MN+ + P ++ E + HQ K EI+ R+E F G L R
Sbjct: 2577 KELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKR 2636
Query: 5911 -KHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPY 6087
+ + K L+ L + W +R L ++ F E WL +E +
Sbjct: 2637 PQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAF 2696
Query: 6088 LISKEYGRNLEETIKLIKKHEAFEK 6162
L + + G + +L+KKH+ FEK
Sbjct: 2697 LNNDDLGDSYTAVERLLKKHDEFEK 2721
Score = 368 bits (945), Expect = e-99
Identities = 388/1851 (20%), Positives = 787/1851 (41%), Gaps = 40/1851 (2%)
Frame = +1
Query: 781 HYFNKL---KQDNIQGKRIGKVINE-------LMENDKMINRYETLSSDLLEWINAKIQL 930
HY +K +++ + GKR K + + L++ K +++ + DL W+ K ++
Sbjct: 1362 HYDSKYIGDRRNQVLGKR--KAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRI 1419
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
+ ++ + L + R+L + + + + +G+L + Q+ ++A N+ VP
Sbjct: 1420 AGDENYRD-LSNLPRKLQKHQAFERELRA----NEGQLRNVTKDGQALVQAGNR---VPE 1471
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR--FNRKAEMRETWLTENQ 1284
+AD+N+ W+ L L L E+ + KLEQ A++ NR E + + E
Sbjct: 1472 VESRVADLNKRWKDL--------LTLSED--KGRKLEQAASQREHNRSLEDAKKKVDELD 1521
Query: 1285 RLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINER 1464
+ + GNDL S + K + +E++I ++++ + + I
Sbjct: 1522 SALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAG 1581
Query: 1465 KENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMD 1644
+ + RR +LE S+ K S +LG +L
Sbjct: 1582 TKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQ 1641
Query: 1645 VEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQK 1824
+ L +KH LE++I +N ++ Q + P E ++ L++
Sbjct: 1642 AQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHP--------EREQVESLCQQLEQ 1693
Query: 1825 RYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLA 2004
+++L ER R+L+ + + Q+ +D E+E + E+ VL ST+ GRD + + LL
Sbjct: 1694 AWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLT 1753
Query: 2005 KHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKE 2184
KHK E L + + S + + P S + + I + L +L++ R+
Sbjct: 1754 KHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQG 1813
Query: 2185 RLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQ 2364
RL + +++F ++D+V++++ + + SSED G+D +QLL K DD+ ++
Sbjct: 1814 RLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGAD 1873
Query: 2365 HIKVLHAKAESL-PQEAREHPDIRQRLDTTLKQKAELENLSQL---RKQRLIDALSLYKL 2532
+ A+ L E+ ++ +R + + + ENL QL R+Q+L A +++
Sbjct: 1874 RVDQCELLAKKLIDSESPYANEVEKRQE---QLRTSWENLLQLLNQREQKLHAAGEIHRF 1930
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKV-TNVNDLAR 2709
+ D I +K L+ + GRD+ + + + E D+ EA++ V D R
Sbjct: 1931 HRDVAEALFRIQDKNAALSQEL-GRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVR 1989
Query: 2710 QLLNVEHP-NSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIE 2886
L ++P N+ I +Q+K+ A W L++ + + L + L+TF D ++ V+W
Sbjct: 1990 --LQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSS 2047
Query: 2887 DKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIER-------E 3045
+ L+ ++ +D +G L+ + + ++ A + K L++ +D + + +
Sbjct: 2048 NLRAALQ-AEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAAD 2106
Query: 3046 RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV 3225
++ A+ ++ +++H W NKK + L++ DL FLRD ++ Q +
Sbjct: 2107 VEEKCAAMLDERQKLHAAW---NKK----KIMLEQKIDLFCFLRDAKQIDNLSSSQQAAL 2159
Query: 3226 ASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLA 3405
+S + Q++ + + + +H I E ++ G ++ +Q ++ L
Sbjct: 2160 SSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLI-EQRHYDSANIQTILQ 2218
Query: 3406 GLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIP----QSL 3573
G+ ++++ + R++ L L F+RD +A+ +++++ L D +L
Sbjct: 2219 GVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNL 2278
Query: 3574 EQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANR 3753
++ +L++HQ F + AN +I+ + G L H ++ +I + + E
Sbjct: 2279 DEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLL 2338
Query: 3754 EKAQEVLKKLKDALSLQQFLSDCDELREWIEEK--MIRAQDETYRDAKTITSKFVRHQAF 3927
+ ++ + L++A +F S D++ WI +K M++A D T RD + + +
Sbjct: 2339 AELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASD-TGRDLEHCNALMRKLDDV 2397
Query: 3928 QSELAANKERLDQLKHAAINLGDDK--PEYHGTIDPQIEELATQWDELEKTTEEKGQKLF 4101
S++ + +R+ + A L + P ++D + ++ W +L+ L
Sbjct: 2398 DSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLG 2457
Query: 4102 DANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID 4281
AN ++ + + D + + M+ D DL V ++++ +E +M Q ID
Sbjct: 2458 GANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKID 2517
Query: 4282 XXXXXXXXXXXXHPDE-LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVD 4458
+P+ ++I+ + + LQA R+ L A +F DV
Sbjct: 2518 QHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVK 2577
Query: 4459 DEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEG 4638
+ +LW+++ + ++ DC + Q EI+ + + G++L
Sbjct: 2578 ELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRP 2637
Query: 4639 HANGP-AFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
P K + L Q L EA +R DL E+ + F + E W++ +E ++
Sbjct: 2638 QQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFL 2697
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
D+ G + + +KKH+ + + AD + L A+ +E + + I+ + A
Sbjct: 2698 NNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQKFANSILEGEPKDADLIREKLAY 2755
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
I + L + R + ++ +W+ K VA ++Y
Sbjct: 2756 ILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVA----LDENYREPSN 2811
Query: 5176 LQERFQQFAR-DTENI-GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLEL 5349
LQ + Q+ A D E + S RV + + LI H IA L W L
Sbjct: 2812 LQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGA 2871
Query: 5350 MDTRAQILEASRLLHKFYHDCRDCLSRIME-KTHAMPDDLGRDSSSVGALSRKHQNYLKD 5526
T+ L+ + F + + + E + +D G+D ++V L +KH+ D
Sbjct: 2872 SQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEAD 2931
Query: 5527 IAAIGEQVAQIERDAAELRDGYAGDKAL--DIGSRESEVVKAWRHLRGLCDARTSRLMDT 5700
+A GE Q+++ + + + L +I R + ++ + L R L D+
Sbjct: 2932 VAHHGELADQLKQKDEQF---FQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDS 2988
Query: 5701 SDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNAC 5880
L +F+ D L W+ E + SQ+ + V+ L H SL+AE+ ++E A
Sbjct: 2989 LSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQAL 3048
Query: 5881 ISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAE 6060
+ G+ ++ H+AS +++ K L + ++ R L +E F +A A+
Sbjct: 3049 LQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEAD 3108
Query: 6061 SWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
+W+ + P L S +YGR+ KK E ++ A + + KL T
Sbjct: 3109 AWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLAT 3159
Score = 354 bits (909), Expect = 1e-95
Identities = 394/1974 (19%), Positives = 817/1974 (40%), Gaps = 49/1974 (2%)
Frame = +1
Query: 886 LSSDLLEWINAKIQLLNERH-FENNLEGVQRQLTEF--NDYRTQEKPPKFDEKGELEVLL 1056
LS +L +N+ + LL + FEN+L ++ QL + R Q K P
Sbjct: 1948 LSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYP------------ 1995
Query: 1057 FTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR 1236
+N ++ K++A AW L+ ER + L L+
Sbjct: 1996 ---------SNASAIAQQQDKVVA----AWNDLK----ERSTARGDRLAASSDLQTFLT- 2037
Query: 1237 FNRKAEMRE--TWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXX 1410
++R+ +W + + + + +D + A +H+AI +I A E++
Sbjct: 2038 -----DVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNEL 2092
Query: 1411 XXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXX 1590
++ A + E+ + +++ LE + +
Sbjct: 2093 SDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLS 2152
Query: 1591 XXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSG 1770
++ L S D G + DV++ ++KH E I E+V+ ++ D +
Sbjct: 2153 SSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSAN 2212
Query: 1771 YKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQV 1950
+ + G + R V DL A R+ +LED +F D AE ++ I E+++
Sbjct: 2213 IQTILQGVLARRQKVK--------DLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKK 2264
Query: 1951 LSSTDTGRDIVT----VSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIP 2118
L + VT L KH+ + + + + + +G L + S I
Sbjct: 2265 LEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIK 2324
Query: 2119 PRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDE 2298
+ + + L R L + +F + D ++ ++ D ++ + D G+D
Sbjct: 2325 RAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDL 2384
Query: 2299 GTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDI----RQRLDTTLKQKA 2466
L++K DDV +++ DQ +K ++ A+ L +A+ D ++R D +
Sbjct: 2385 EHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWR- 2443
Query: 2467 ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFD 2646
+L+ + L A ++ D D I EK +++ GRD+ VE + R +
Sbjct: 2444 QLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREE 2503
Query: 2647 TLEQDMKNQEAKVTNVNDLARQLLNVEHPN--SDDILHRQNKLNARWAQLRDMVDQKRNE 2820
LE+DM + K+ ++ A + L ++P + I + +L+ W L+ + ++++
Sbjct: 2504 ALERDMSAVKQKIDQ-HETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSI 2562
Query: 2821 LERAHRLETFRIDCQETVTWIEDKTRVLED--SDALTNDLSGVMKLQRRLSMMERDLGAI 2994
L A+ F D +E W+ D + + + S + ND ++L + + ++
Sbjct: 2563 LNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKV---EIEGR 2619
Query: 2995 QAKLDSLHKEADDIERERPQEAQA--IREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
Q L ++ + + + RPQ+ Q +R+ + + ++ LN+ E L EA LQ
Sbjct: 2620 QEAFAGLKQQGEQLSK-RPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQL 2678
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
F ++ + WL + + +++ S E+LL +H + + +A+ ++ +
Sbjct: 2679 FKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQKFAN 2736
Query: 3349 RVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLS 3528
+ + + + +R++LA + ++L + + R+ L+Q LQ FLR + + L
Sbjct: 2737 SILEGEPKDADL-IREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLV 2795
Query: 3529 QQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKI 3708
Q+ +A D+ + ++++++H F + +N ++++V G++L + H+A D+I
Sbjct: 2796 QKLQ-VALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEI 2854
Query: 3709 HKKARNID----ERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDET 3876
++ + ++ + +GA++ K KL+ A F DE W++E ++ E
Sbjct: 2855 AQQVQLLEGDWLKLKGASQTKKD----KLQQAYDALAFNRSVDEFNNWMDEVELQLSSED 2910
Query: 3877 Y-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQ 4053
Y +D +++ +H+ ++++A + E DQLK + I + +
Sbjct: 2911 YGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRR 2970
Query: 4054 WDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK 4233
++ L + + + L D+ Q +++ D +W + + +D L +V +K
Sbjct: 2971 YNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKK 3030
Query: 4234 QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKA 4413
+ +E E+ + I + E ++ +Q+QL +L+ RR
Sbjct: 3031 HNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLR 3090
Query: 4414 LERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPW 4593
L + F + ++ W+ E+ + + + G QK L++L E+ +P
Sbjct: 3091 LLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPS 3150
Query: 4594 INQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDC 4773
I ++ LI+ H + +K ++ +++L K+R+ LGE +K ++L +
Sbjct: 3151 IEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRET 3210
Query: 4774 GEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE 4953
E W+ +Q ++ G+D + I E S+++ + A + + ++E
Sbjct: 3211 EELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQE 3270
Query: 4954 KSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVA 5133
+P I+ ++ + ++L+ L+D + R D+ +Q I +K+
Sbjct: 3271 NNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASL 3330
Query: 5134 GSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPT-IALWK 5310
S++ GQD E +Q L + Q F ++E +G + ++ +G + DA I + +
Sbjct: 3331 ISEDYGQDLESIQALGRKHQVF--ESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKR 3388
Query: 5311 DSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSV 5487
D EAW +L E R L + L ++ + RD ++ I E + +L +
Sbjct: 3389 DETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGA 3448
Query: 5488 GALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEV-VKAWRH--L 5658
L +++ +I E A+ + +L +K E ++ V RH L
Sbjct: 3449 ELLLASTKDHDTEIRTRDETFAKFAANGQQL----IKEKHFLAHEVEDKIKVLQARHELL 3504
Query: 5659 RGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSL 5838
+ + R D F+ L W+ + ++ + + VE L+ H+
Sbjct: 3505 KHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDF 3564
Query: 5839 KAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTT-ERAEMMRRWEDRWEYLQL 6015
+ + A+EE F A + R + + + ++K+ KL ER E R + + LQ
Sbjct: 3565 EKTVAAQEEKFQA---IKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQR 3621
Query: 6016 ILEV-------YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFA 6174
+ + ++ ++AA E P + + + ++ + F
Sbjct: 3622 LADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQL-----RPPFG 3676
Query: 6175 QEERFLALEKLTTFELKETQHRE---EETAKRRGPAHIG-SPSRSTPAAETSFGAQDDGA 6342
+ LAL+K ++ + + R + KR + ++ TP+ T AQ
Sbjct: 3677 DDNEHLALQKSSSSGMFGDRLRRGSADANVKRAESMKVQPKQAKRTPSFTTRRRAQSFRK 3736
Query: 6343 KQ-GEAFE-------GTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES 6498
Q GE F+ G+L RKH +S +KA RSW++ + VL + F+KD +
Sbjct: 3737 NQKGEGFDLPPVEIQGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQ 3796
Query: 6499 VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL 6660
P+ + G A DY KKK V L+LP G+E+LF+ S + + W+ ++
Sbjct: 3797 KTATAPVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKI 3850
Score = 326 bits (835), Expect = 6e-87
Identities = 355/1808 (19%), Positives = 727/1808 (39%), Gaps = 26/1808 (1%)
Frame = +1
Query: 814 QGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFN 993
Q ++ G + +E++ + + LL WI++ LN ++E L + N
Sbjct: 1170 QVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHN 1229
Query: 994 DYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIAD---INRAWQSLEKA 1164
D + + +EV+ Q + N V +L A+ I+R W A
Sbjct: 1230 DLGDDIRA---HDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGW-----A 1281
Query: 1165 EHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATK 1344
E ++ L+ +L FNR+A+ + ++ + +N G L VEA K
Sbjct: 1282 EKQKWLLQCVDL----------QMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILK 1331
Query: 1345 KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRV 1524
+H E + A ++ +++D I +R+ V R+
Sbjct: 1332 RHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKR 1391
Query: 1525 RLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE 1704
L+ S K F K+R+ ++ L ++ LQKH E ++
Sbjct: 1392 LLQASKDFHK-FAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEG 1450
Query: 1705 RVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNK 1884
++ N Q G+ VE D L KR+K+LL L+ ++ R+LE
Sbjct: 1451 QLRNVTKDGQALVQA----GNRVPEVESRVAD-----LNKRWKDLLTLSEDKGRKLEQAA 1501
Query: 1885 RLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLD 2064
+ + + + + E + L S D G D+ + L+ K + E+ + ++ + L
Sbjct: 1502 SQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELV 1561
Query: 2065 VSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDR 2244
+G ++ + NI E++ L++ + R+ +L + Y++F + D +
Sbjct: 1562 STGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQ 1621
Query: 2245 YLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP 2424
++ + L S ++G++ Q L KKH + E++ I +SL +++HP
Sbjct: 1622 WINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSL--ISQQHP 1679
Query: 2425 DIRQRLDTTLKQK----AELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLAT 2592
+ R+++++ +Q +LE R ++L +L + DA +ESW+ E+ +L +
Sbjct: 1680 E-REQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRS 1738
Query: 2593 LVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLN 2772
GRD + + + T+E ++ VT + ++ HP+S + +Q +
Sbjct: 1739 TEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIE 1798
Query: 2773 ARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL 2952
L + Q++ L + + ++ E WI ++ + D D + L
Sbjct: 1799 KMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSED-YGQDFEHLQLL 1857
Query: 2953 QRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREH 3132
Q + ++ + ++D A + A + + +++ W+ L + + +
Sbjct: 1858 QNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQR 1917
Query: 3133 EAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA-SEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E KL AG++ RF RD+ +A + A S+E + L A LL +H +G
Sbjct: 1918 EQKLHAAGEIHRFHRDV--AEALFRIQDKNAALSQELGRDLNSALALLRKH-------EG 1968
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMF------LRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
+ D + A + +D Q + + Q+ + W +L+ R L+
Sbjct: 1969 FENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAA 2028
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
+LQ FL D + S L ++ A +H ++A ++K R
Sbjct: 2029 SSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRY 2088
Query: 3652 VGMFGDQLCQDGHYAADKIHKK-ARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
+ D + Q GHYAA + +K A +DER+ + ++ + L+ + L FL D +
Sbjct: 2089 LNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKI-MLEQKIDLFCFLRDAKQ 2147
Query: 3829 LREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
+ + + + + + +K +H F+ + +E++ L+ L + +
Sbjct: 2148 IDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRH 2207
Query: 4006 EYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ----LEN 4173
I ++ + + +++ + KL DA +V+ A+ K W + LE
Sbjct: 2208 YDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEA 2267
Query: 4174 EMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHR 4353
+ + +L +QK + E+ I + IK
Sbjct: 2268 DAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAI 2327
Query: 4354 LAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
V E Q L A L+ R + LE + + +F +D + WI ++ ++ +A + G L C
Sbjct: 2328 EIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHC 2387
Query: 4534 HRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGH--ANGPAFEKKIQELRSAWQELKE 4707
+ L + L + +++ + + I +LI++ A+ + +K+ ++ W++L+
Sbjct: 2388 NALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQG 2447
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
A+ + LG + + H F D + ++E+ L M + G+D + + I++ E L+
Sbjct: 2448 ALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALER 2507
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPL--TEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXX 5061
D+ I T A +F+ +K P + I+ + ++ K + LQ
Sbjct: 2508 DMSAVKQKIDQHETAA-EFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEA 2566
Query: 5062 XXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVAN 5241
+ ++ +L W+ D + ++ + E Q+ + E E A
Sbjct: 2567 YLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEG-RQEAFAG 2625
Query: 5242 ANDGCDTLIGHGHTDAP-TIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
+ L P + + L E + L E RA+ L + L F
Sbjct: 2626 LKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQ 2685
Query: 5419 CLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYA 5595
+ K + DDLG ++V L +KH + K + A + V +++ A + +G
Sbjct: 2686 VEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEP 2743
Query: 5596 GDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMN 5775
D L I + + +++ + L L + R RL + L +F+ + ++ W+ + K ++
Sbjct: 2744 KDADL-IREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQ-KLQVA 2801
Query: 5776 SQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKL 5955
E ++ S ++ + H + AE+ + + I G L+ H+A EI +++ L
Sbjct: 2802 LDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLL 2861
Query: 5956 TTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKL 6135
+ ++ + + + LQ + F R +W+ E L S++YG++L L
Sbjct: 2862 EGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNL 2921
Query: 6136 IKKHEAFE 6159
+KKHE E
Sbjct: 2922 LKKHERLE 2929
Score = 249 bits (637), Expect = 5e-64
Identities = 285/1580 (18%), Positives = 623/1580 (39%), Gaps = 25/1580 (1%)
Frame = +1
Query: 1600 KSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKP 1779
K R++ D G V++ +K +D++ +RV FR G+
Sbjct: 997 KERMIKSDEGE---GVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRR------QGHSQ 1047
Query: 1780 VEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSS 1959
++ I R + + ++ L + A+R++ LE + F E + + E+ L +
Sbjct: 1048 LDK--IIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDT 1105
Query: 1960 TDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIR 2139
D+ TV L +H+N E L +E ++R+ G +++ DN+ R E++
Sbjct: 1106 AVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQ 1165
Query: 2140 DYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLL 2319
D ++++ + + R+ V F A + ++ +++++ +D T LL
Sbjct: 1166 DMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLL 1225
Query: 2320 KKHDDVHDELQNFD-QHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQ--L 2490
KKH+D+ D+++ D + ++V+ Q + P++ + + + KAE + + +
Sbjct: 1226 KKHNDLGDDIRAHDTEFVEVIQLG----KQLSDGKPNMAETVAVIERLKAEQDAIHRGWA 1281
Query: 2491 RKQR-LIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMK 2667
KQ+ L+ + L +AD +++ L G ++EVE + R E+ +
Sbjct: 1282 EKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLM 1341
Query: 2668 NQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLET 2847
Q+ + +D A +L++ +H +S I R+N++ + ++D +++ L+ +
Sbjct: 1342 AQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHK 1401
Query: 2848 FRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEA 3027
F + + W++DKTR+ D + DLS + + ++ ER+L A + +L ++ K+
Sbjct: 1402 FAAEADDLKVWLQDKTRIAGDEN--YRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDG 1459
Query: 3028 DDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLT 3207
+ + + + +++ W L + KL++A + R L+ + +
Sbjct: 1460 QALV-QAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVD 1518
Query: 3208 ATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMF 3387
+ S + L + L+N+ + EI + + ++ + GD D +
Sbjct: 1519 ELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGD----DMAHGGHFN 1574
Query: 3388 LRQRLAG---LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDD 3558
+ AG LQ+ +++L+ R+ L + LN F+ + +++ ++
Sbjct: 1575 AQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNE 1634
Query: 3559 IPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDER 3738
+ Q+L QA++ K+H+ + + I + G L H +++ + +++
Sbjct: 1635 LGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQA 1694
Query: 3739 RGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITSKFVR 3915
E +KL +L QQ+L D E+ W+ E + E RD + +
Sbjct: 1695 WQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTK 1754
Query: 3916 HQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQK 4095
H+ + EL + ++ H+ + + + + + L K ++ +
Sbjct: 1755 HKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGR 1814
Query: 4096 LFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQH 4275
L ++ + Y ++++W + E + ED D + + K ++ + A
Sbjct: 1815 LMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADR 1874
Query: 4276 IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDV 4455
+D ++ + ++ + L L+ R + L +F RDV
Sbjct: 1875 VDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDV 1934
Query: 4456 DDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDE 4635
+ I ++ A +Q LG L L + + N++ E + + + L +
Sbjct: 1935 AEALFRIQDKNA-ALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAK 1993
Query: 4636 GHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
+N A ++ ++ +AW +LKE R L S FL D + +W S +
Sbjct: 1994 YPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAAL 2053
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
+E D +H+ + +I+ D R L + V+ ++ + A
Sbjct: 2054 QAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAA 2113
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
+ L + R+ + + ++ S + GQ E VQ
Sbjct: 2114 MLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQN 2173
Query: 5176 LQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMD 5355
+ +F R + E+V+ + LI H D+ I + + + +L
Sbjct: 2174 KIRKHDEFERLIQT-QEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCA 2232
Query: 5356 TRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR-----KHQNYL 5520
R LE + L KF DC + I EK + D + + KHQ +
Sbjct: 2233 VRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQ 2292
Query: 5521 KDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDT 5700
++AA ++ +I+ D + + + +I V++AW+ L + R L +
Sbjct: 2293 AEVAANQGRIQEIQ-DTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEA 2351
Query: 5701 SDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNAC 5880
D +F + + + W+ + + + + + +D+ LM + +++ ++
Sbjct: 2352 QDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHI 2411
Query: 5881 ISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRR-WEDRWEYLQLIL-----------E 6024
L L+N+ + T+ + R+ + W LQ L E
Sbjct: 2412 NQLADKLINQAQ----------VPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANE 2461
Query: 6025 VYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
++ F RD + + + S + GR+L LI++ EA E+ A +++ E
Sbjct: 2462 IHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHET 2521
Query: 6205 LTTFELKETQHREEETAKRR 6264
F +K+ R + +R+
Sbjct: 2522 AAEFLIKKYPERGAQHIERK 2541
Score = 39.7 bits (91), Expect = 1.0
Identities = 48/213 (22%), Positives = 92/213 (42%), Gaps = 21/213 (9%)
Frame = +1
Query: 5686 RLMDTS-DLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSL----- 5838
+LMD ++ + +LL W+ + E+ ++ P + G++ L ++++
Sbjct: 270 QLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPK 329
Query: 5839 ---KAEIDAREENFNACISLGRDLLNRKHYAS------SEIEK--KLIKLTTERAEMMRR 5985
++EI+A N + LN+ Y ++IEK ++++ E+ R
Sbjct: 330 YKERSEIEALYFTINTLLKA----LNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALR 385
Query: 5986 WED-RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
E R E L+ + Y+F + + + E +L L Y R ++ T+K KHEA
Sbjct: 386 DELLRQEKLEQLN--YKFEKKSVLREGYLKEMIQVLSDPRYLRQVDATLK---KHEAISA 440
Query: 6163 SAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
A+ ERF L + +E H +E +R
Sbjct: 441 DILARVERFNDLTAMAEELDRENYHGKERVRRR 473
>gi|45552923|ref|NP_995988.1| CG12008-PB [Drosophila melanogaster]
gi|45445784|gb|AAS64958.1| CG12008-PB [Drosophila melanogaster]
Length = 4118
Score = 989 bits (2558), Expect = 0.0
Identities = 654/2211 (29%), Positives = 1074/2211 (47%), Gaps = 168/2211 (7%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGER 255
FE RIK L +ER +QKKTFTKW+NS L++ +V+DL+ D+ DG LL+LL ++S E+
Sbjct: 10 FENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEK 69
Query: 256 LPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQI 435
L KP G+MR+H +ENV K L FL + V LE++G+ DIVDGN RL LGLIWTIILRFQI
Sbjct: 70 LGKPNSGRMRVHKIENVNKSLAFLHTK-VRLESIGAEDIVDGNPRLILGLIWTIILRFQI 128
Query: 436 QDITF---EDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHR 606
Q+I E+ ++ E RSAK+ALLLWCQ KT GYP VN+ +F+ SWR GL FNALIH HR
Sbjct: 129 QEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHR 188
Query: 607 PDLVDYDNL--QKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
PDL +Y + K++ L NL AFDTA N+LG+ LDAED++ +PDEKSI+TYV +YY
Sbjct: 189 PDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYY 248
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
H F ++K + GKRI ++ +LM+ D+ +YE L+++LL WI K L +R N+L
Sbjct: 249 HTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSL 308
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
EG+QR+L F +YRT EKPPK+ E+ E+E L FT+ + ++A NQ P+ P++G+L+ DI +
Sbjct: 309 EGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEK 368
Query: 1141 AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDL 1320
AWQ LE AEH RE+ L++EL+RQEKLEQL +F +K+ +RE +L E +++S + L
Sbjct: 369 AWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRY---L 425
Query: 1321 SSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXX 1500
V+A KKHEAI DI A ER NYH + ++ R++ V
Sbjct: 426 RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLL 485
Query: 1501 XXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLE 1680
+R+ L + + ++ + SED+G HL+ VE+LLQ H+L E
Sbjct: 486 ELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQE 545
Query: 1681 SDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAER 1860
+N GE + QA +++ + D + + +R L++ Y ELL +A R
Sbjct: 546 LQVNTYGETLKRFNRQALPYKSSEHKDAA--------LLAQRLADLEEAYSELLRRSAAR 597
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
+ RLE+ + F D E + +++++ + T +D+ V L KHK E+ ++
Sbjct: 598 RARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSR 657
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
+ ++ +GK L E P S I R+ + ++ L+ L R+ +L E YQF+
Sbjct: 658 KPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFY 717
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
TDA++ + +L + + +++S D G DE + Q LL++H D+ EL + I L+ +A+ L
Sbjct: 718 TDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKL 777
Query: 2401 PQEA----------REHPDIRQR---LDTTLKQK--------AELENLSQLRKQRLIDAL 2517
+ E P++ Q +T L K +LE+ + L
Sbjct: 778 IKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVK 837
Query: 2518 SLY--------------KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLE 2655
SL+ L + + W K + VP + EVE +
Sbjct: 838 SLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPK 897
Query: 2656 QDMKNQEAKVTNVNDLARQLLNVE----------------------HPNSDDILHRQNKL 2769
+ KV L RQ++ V+ + N+D + RQ ++
Sbjct: 898 AEKVKSLQKVKK-TILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRI 956
Query: 2770 NARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMK 2949
N + +L++M ++ LE + L F +C + W+++K R+++ + GV
Sbjct: 957 NQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEG-----EGVDN 1011
Query: 2950 LQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVRE 3129
+R+ DL A +++ + D R+ + I ++IHQ+W LN +
Sbjct: 1012 AKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQ 1071
Query: 3130 HEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E L+ A ++ F R D + W++ Q+ + L + L +H + E+
Sbjct: 1072 REKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAP 1131
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQM 3489
+ ++ +G+ V ++ + + R +Q+ W+++Q+ + ++ + + Q+
Sbjct: 1132 VEDKVNRVTYLGNSV-KNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQV 1190
Query: 3490 FLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGD 3669
F AK + ++ L D+ + +E A N LK+H D + A+D + V G
Sbjct: 1191 FNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGK 1250
Query: 3670 QLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL------ 3831
QL A+ + R E+ +R A E K L + LQ F + D++
Sbjct: 1251 QLSDGKPNMAETVAVIERLKAEQDAIHRGWA-EKQKWLLQCVDLQMFNREADKIDATTKS 1309
Query: 3832 ----------------------REWIEEKMIRAQDETYR---------------DAKTI- 3897
R EK + AQD+ + D+K I
Sbjct: 1310 HEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIG 1369
Query: 3898 --------TSKFVRHQAFQSE--LAANKE------RLDQLK----HAAINLGDDKPEYHG 4017
K V+ +AF+ + L A+K+ D LK GD+
Sbjct: 1370 DRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLS 1429
Query: 4018 TIDPQIE-------ELATQWDELEKTTEEKGQKLFDANRQQLYVQS-IADM-KEW----- 4155
+ +++ EL +L T++ GQ L A + V+S +AD+ K W
Sbjct: 1430 NLPRKLQKHQAFERELRANEGQLRNVTKD-GQALVQAGNRVPEVESRVADLNKRWKDLLT 1488
Query: 4156 ------------ATQLENEMTREDQP----------------GDLTTVNVAMQKQHLIET 4251
A+Q E+ + ED DL + + KQ ++E+
Sbjct: 1489 LSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILES 1548
Query: 4252 EMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
E+ Q + +NI+A +Q++ + L+ P RR LE
Sbjct: 1549 EITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLN 1608
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
+F ++D E WI+E L AK+ LG++L L K + L EI H+P IN+
Sbjct: 1609 YHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALV 1668
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
GQ LI + H E Q+L AWQ+L+ +R L S KA Q+L+D GE E+W
Sbjct: 1669 AGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESW 1728
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+ E+ + E G+D S + KH+ ++ ++D ++ + + V P ++
Sbjct: 1729 LGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSK 1788
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENG 5151
+ +Q IEK+ L + E D++ QWI ++E A S++ G
Sbjct: 1789 VLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYG 1848
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
QD+EH+Q+LQ +F E +G++RV LI A + ++ L +W
Sbjct: 1849 QDFEHLQLLQNKFDDLKHRVE-VGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSW 1907
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQ 5511
ENLL+L++ R Q L A+ +H+F+ D + L RI +K A+ +LGRD +S AL RKH+
Sbjct: 1908 ENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHE 1967
Query: 5512 NYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRL 5691
+ D+ A+ Q+ + D+ L+ Y + A I ++ +VV AW L+ AR RL
Sbjct: 1968 GFENDLVALEAQLQVLVEDSVRLQAKYPSN-ASAIAQQQDKVVAAWNDLKERSTARGDRL 2026
Query: 5692 MDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENF 5871
+SDL F+ VRD++ W ++ + ++E D +G L H ++ EI+ARE+ F
Sbjct: 2027 AASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKF 2086
Query: 5872 NACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAA 6051
L ++ HYA++++E+K + ER ++ W + L+ ++++ F RDA
Sbjct: 2087 RYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAK 2146
Query: 6052 VAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
++ +Q+ L S ++G+ +E+ I+KH+ FE+ QEE+ L++
Sbjct: 2147 QIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQE 2197
Score = 575 bits (1481), Expect = e-162
Identities = 437/1831 (23%), Positives = 827/1831 (44%), Gaps = 18/1831 (0%)
Frame = +1
Query: 811 IQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEF 990
+ +R G+++ L +++ + S ++ +WI + Q + + + E +Q +F
Sbjct: 1807 LASQRQGRLMESLYKHEYFLE-----SDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKF 1861
Query: 991 NDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEH 1170
+D + + + D + E+L L +++ P+ K + +W++L + +
Sbjct: 1862 DDLKHRVEVGA-DRVDQCELLAKKL-----IDSESPYANEVEKRQEQLRTSWENLLQLLN 1915
Query: 1171 ERELVLKEELIRQEKLEQLAA--RFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATK 1344
+RE +KL RF+R + + +SQ+ G DL+S A +
Sbjct: 1916 QRE----------QKLHAAGEIHRFHRDVAEALFRIQDKNAALSQE-LGRDLNSALALLR 1964
Query: 1345 KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRV 1524
KHE E D+ A E + + + I ++++ V AR
Sbjct: 1965 KHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGD 2024
Query: 1525 RLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE 1704
RL S +Q +++ L +E+ + L +H + +I +
Sbjct: 2025 RLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEARED 2084
Query: 1705 R------VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKR 1866
+ +++S+ Q + D ++E+ + ++L ++K
Sbjct: 2085 KFRYLNELSDSMVQTGHYAAAD--------------VEEKCAAMLDERQKLHAAWNKKKI 2130
Query: 1867 RLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEK 2046
LE L F D ++++ Q+ LSS+D G+ + V + + KH E ++ E+
Sbjct: 2131 MLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEE 2190
Query: 2047 YLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTD 2226
+ L G++L ++ S NI L + K+K+L A R+ +L + Y +F D
Sbjct: 2191 KVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRD 2250
Query: 2227 ADDVDRYLYDTLRVMSSEDVGKDEGTVQ----LLLKKHDDVHDELQNFDQHIKVLHAKAE 2394
+ ++ + + + ++ E T L+KH E+ I+ +
Sbjct: 2251 CAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGV 2310
Query: 2395 SLPQEAREH-PDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDE 2571
L + E P+I++ ++ L+ L + R + L +A + S D +E+WI +
Sbjct: 2311 ILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRD 2370
Query: 2572 KGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSD--D 2745
K ++ GRD+E + + D ++ DM+ + +V ++N LA +L+N +D
Sbjct: 2371 KEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQS 2430
Query: 2746 ILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALT 2925
+ R+ N W QL+ ++ R L A+ + F D +T I +K+ + +D
Sbjct: 2431 VDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDT-G 2489
Query: 2926 NDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQE-AQAIREDIKRIHQVW 3102
DL+ V L RR +ERD+ A++ K+D A+ + ++ P+ AQ I ++ +H+ W
Sbjct: 2490 RDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSW 2549
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
L + ++ L+EA +F+ D+ + W+ +++ + + P ++ + E L H
Sbjct: 2550 GNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELH 2609
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHL 3462
+ EI+G E + ++ G+++++ Q +R+ L L+E + L W R
Sbjct: 2610 QERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARD 2669
Query: 3463 LSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEK 3642
L++ LQ+F +Q E+ L+ +E +L DD+ S E LK+H +F + A +
Sbjct: 2670 LTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHA--DH 2727
Query: 3643 IRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDC 3822
+ + F + + + AD I +K I R+ E ++E ++L + LQ+FL
Sbjct: 2728 VDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSL 2787
Query: 3823 DELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDK 4002
E+ W+ +K+ A DE YR+ + SK +H AF +EL +N R+ + H L
Sbjct: 2788 YEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGD 2847
Query: 4003 PEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMT 4182
I Q++ L W +L+ ++ K KL A + +S+ + W ++E +++
Sbjct: 2848 HFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLS 2907
Query: 4183 REDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAV 4362
ED DL V+ ++K +E ++ + D I
Sbjct: 2908 SEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVS 2967
Query: 4363 QEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRL 4542
+ L PL RR+ LE + QF RD +DE W++E+ ++A +Q+LG SL L
Sbjct: 2968 IRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGL 3027
Query: 4543 QKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDR 4722
QK L E+ + EP I + GQ++I + H + K + L+ +L++ R
Sbjct: 3028 QKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIR 3087
Query: 4723 KGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKF 4902
+ L ++ ++ F + EA+AWM E+ + + G+DE S + KK E LQ ++ F
Sbjct: 3088 RLRLLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAF 3147
Query: 4903 ADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALH 5082
+I +A A +E + I + AQ+ + Y L +
Sbjct: 3148 KPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYL 3207
Query: 5083 REIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDT 5262
RE ++L +W+ D+ V S++ G+D EHV+ L F+ F + N RV + D
Sbjct: 3208 RETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNL-NANEARVEACLERGDR 3266
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
LI + +I +D + WE L +L+ R L ++ +H + + + I EK
Sbjct: 3267 LIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEK 3326
Query: 5443 THAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
++ +D G+D S+ AL RKHQ + ++ I QV + +AA+L + Y K I
Sbjct: 3327 DASLISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKE-HIE 3385
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
+ E V+AW L+ AR ++L L + + RDL+ W++E+ ++ + E V
Sbjct: 3386 VKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSV 3445
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
+G ELL+ + + EI R+E F + G+ L+ KH+ + E+E K IK+ R E++
Sbjct: 3446 AGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDK-IKVLQARHELL 3504
Query: 5980 RRW-EDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+ R E +L L+ F +DA + E W+ ++EP L + G ++ + L+++HE F
Sbjct: 3505 KHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDF 3564
Query: 6157 EKSAFAQEERFLALEKLTTFELKETQHREEE 6249
EK+ AQEE+F A++++T E E+E
Sbjct: 3565 EKTVAAQEEKFQAIKRITMLEQLFRHQLEQE 3595
Score = 392 bits (1006), Expect = e-107
Identities = 348/1705 (20%), Positives = 705/1705 (40%), Gaps = 23/1705 (1%)
Frame = +1
Query: 1117 KLIA---DINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQR 1287
K+IA I++ WQ L A+ +RE L+ FNR + + W++E
Sbjct: 1050 KIIARQRQIHQIWQRLNNAKAQREKSLEGA--------SSVELFNRTCDEAKVWMSEKML 1101
Query: 1288 LVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERK 1467
+ DL +V+A ++H+ +E ++ E++ ++ +N R+
Sbjct: 1102 QLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQ 1161
Query: 1468 ENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDV 1647
+ V R R+E + Q + +K +L +++ +
Sbjct: 1162 QEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETA 1221
Query: 1648 EDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKR 1827
+LL+KH L DI I ++ DG + D + +
Sbjct: 1222 NNLLKKHNDLGDDIRAHDTEFVEVIQLGKQL--SDGKPNMAETVAVIERLKAEQDAIHRG 1279
Query: 1828 YKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAK 2007
+ AE+++ L L F + +++ K E L + G + V +L +
Sbjct: 1280 W-------AEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKR 1332
Query: 2008 HKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKER 2187
H + E +L +K L + +L S I R ++ +K+ + RK
Sbjct: 1333 HLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRL 1392
Query: 2188 LAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQH 2367
L ++++F +ADD+ +L D R+ E+ +D + L+KH EL+ +
Sbjct: 1393 LQASKDFHKFAAEADDLKVWLQDKTRIAGDENY-RDLSNLPRKLQKHQAFERELRANEGQ 1451
Query: 2368 IKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDAD 2547
++ + ++L Q P++ R+ K+ +L LS+ + ++L A S + +
Sbjct: 1452 LRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLE 1511
Query: 2548 SVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE 2727
+ +DE L + G D+ + + ++ LE ++ + KV + + +
Sbjct: 1512 DAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGG 1571
Query: 2728 HPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
H N+ +I +L R+ LRD ++R +LE + F + WI + +
Sbjct: 1572 HFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAK 1631
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKR 3087
S+ L +L L ++ +E ++ Q ++ + ++ E + + ++
Sbjct: 1632 -SNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQ 1690
Query: 3088 IHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQ 3267
+ Q W L + E KLD + Q++L D ++WL + S E + A +
Sbjct: 1691 LEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAK 1750
Query: 3268 LLNQHAAIREEIDGYAEDYKKM-RAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMW 3444
LL +H I E+D Y+ +M + V + D + + +Q+L +++ + L ++
Sbjct: 1751 LLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQL--IEKMLKSLHKLA 1808
Query: 3445 DNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTM 3624
RQ L + L + ++ + E + +QE + +D Q E + + D +
Sbjct: 1809 SQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRV 1868
Query: 3625 DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQ 3804
+ +++ + +L A+++ K+ + + + +KL A +
Sbjct: 1869 EVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIH 1928
Query: 3805 QFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAI 3984
+F D E I++K E RD + + +H+ F+++L A + +L L ++
Sbjct: 1929 RFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSV 1988
Query: 3985 NLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ 4164
L P I Q +++ W++L++ + +G +L ++ Q ++ + D+ W++
Sbjct: 1989 RLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSN 2048
Query: 4165 LENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIK 4344
L + E+ D + I E+ + +++
Sbjct: 2049 LRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVE 2108
Query: 4345 AHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESL 4524
A+ ++ Q+L A + ++ LE+K F F RD S + + + G+++
Sbjct: 2109 EKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTV 2168
Query: 4525 PDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELK 4704
D + I E ++ + +G++LI++ H + + +Q + + Q++K
Sbjct: 2169 EDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVK 2228
Query: 4705 EAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ----IKKH 4872
+ R+ L ++ +F+ DC EA+ W++E++ + D E + ++ ++KH
Sbjct: 2229 DLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKH 2288
Query: 4873 ERLQSD-------IDKFADTIRALATKAHKFVEEKSPLTEQI----QVRQAQIEKLYAGL 5019
+ Q++ I + DT L +K H+ E E + Q A++E+ GL
Sbjct: 2289 QAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGL 2348
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQF 5199
++ + ++D + WI DKE++ + + G+D EH L +
Sbjct: 2349 EE-----------AQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDV 2397
Query: 5200 ARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWK--DSLNEAWENLLELMDTRAQIL 5373
D + +RV + N D LI A T ++ K N W L ++ +L
Sbjct: 2398 DSDM-RVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALL 2456
Query: 5374 EASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQV 5550
+ +H F D D RI EK+ AM D GRD ++V AL R+ + +D++A+ +++
Sbjct: 2457 GGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKI 2516
Query: 5551 AQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMV 5730
Q E A L Y A I + E+ K+W +L+ L R S L + KF++ V
Sbjct: 2517 DQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDV 2576
Query: 5731 RDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR 5910
++L LW++++ ++MN+ + P ++ E + HQ K EI+ R+E F G L R
Sbjct: 2577 KELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKR 2636
Query: 5911 -KHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPY 6087
+ + K L+ L + W +R L ++ F E WL +E +
Sbjct: 2637 PQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAF 2696
Query: 6088 LISKEYGRNLEETIKLIKKHEAFEK 6162
L + + G + +L+KKH+ FEK
Sbjct: 2697 LNNDDLGDSYTAVERLLKKHDEFEK 2721
Score = 368 bits (945), Expect = e-99
Identities = 388/1851 (20%), Positives = 787/1851 (41%), Gaps = 40/1851 (2%)
Frame = +1
Query: 781 HYFNKL---KQDNIQGKRIGKVINE-------LMENDKMINRYETLSSDLLEWINAKIQL 930
HY +K +++ + GKR K + + L++ K +++ + DL W+ K ++
Sbjct: 1362 HYDSKYIGDRRNQVLGKR--KAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRI 1419
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
+ ++ + L + R+L + + + + +G+L + Q+ ++A N+ VP
Sbjct: 1420 AGDENYRD-LSNLPRKLQKHQAFERELRA----NEGQLRNVTKDGQALVQAGNR---VPE 1471
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR--FNRKAEMRETWLTENQ 1284
+AD+N+ W+ L L L E+ + KLEQ A++ NR E + + E
Sbjct: 1472 VESRVADLNKRWKDL--------LTLSED--KGRKLEQAASQREHNRSLEDAKKKVDELD 1521
Query: 1285 RLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINER 1464
+ + GNDL S + K + +E++I ++++ + + I
Sbjct: 1522 SALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAG 1581
Query: 1465 KENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMD 1644
+ + RR +LE S+ K S +LG +L
Sbjct: 1582 TKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQ 1641
Query: 1645 VEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQK 1824
+ L +KH LE++I +N ++ Q + P E ++ L++
Sbjct: 1642 AQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHP--------EREQVESLCQQLEQ 1693
Query: 1825 RYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLA 2004
+++L ER R+L+ + + Q+ +D E+E + E+ VL ST+ GRD + + LL
Sbjct: 1694 AWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLT 1753
Query: 2005 KHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKE 2184
KHK E L + + S + + P S + + I + L +L++ R+
Sbjct: 1754 KHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQG 1813
Query: 2185 RLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQ 2364
RL + +++F ++D+V++++ + + SSED G+D +QLL K DD+ ++
Sbjct: 1814 RLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGAD 1873
Query: 2365 HIKVLHAKAESL-PQEAREHPDIRQRLDTTLKQKAELENLSQL---RKQRLIDALSLYKL 2532
+ A+ L E+ ++ +R + + + ENL QL R+Q+L A +++
Sbjct: 1874 RVDQCELLAKKLIDSESPYANEVEKRQE---QLRTSWENLLQLLNQREQKLHAAGEIHRF 1930
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKV-TNVNDLAR 2709
+ D I +K L+ + GRD+ + + + E D+ EA++ V D R
Sbjct: 1931 HRDVAEALFRIQDKNAALSQEL-GRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVR 1989
Query: 2710 QLLNVEHP-NSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIE 2886
L ++P N+ I +Q+K+ A W L++ + + L + L+TF D ++ V+W
Sbjct: 1990 --LQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSS 2047
Query: 2887 DKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIER-------E 3045
+ L+ ++ +D +G L+ + + ++ A + K L++ +D + + +
Sbjct: 2048 NLRAALQ-AEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAAD 2106
Query: 3046 RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV 3225
++ A+ ++ +++H W NKK + L++ DL FLRD ++ Q +
Sbjct: 2107 VEEKCAAMLDERQKLHAAW---NKK----KIMLEQKIDLFCFLRDAKQIDNLSSSQQAAL 2159
Query: 3226 ASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLA 3405
+S + Q++ + + + +H I E ++ G ++ +Q ++ L
Sbjct: 2160 SSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLI-EQRHYDSANIQTILQ 2218
Query: 3406 GLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIP----QSL 3573
G+ ++++ + R++ L L F+RD +A+ +++++ L D +L
Sbjct: 2219 GVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNL 2278
Query: 3574 EQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANR 3753
++ +L++HQ F + AN +I+ + G L H ++ +I + + E
Sbjct: 2279 DEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLL 2338
Query: 3754 EKAQEVLKKLKDALSLQQFLSDCDELREWIEEK--MIRAQDETYRDAKTITSKFVRHQAF 3927
+ ++ + L++A +F S D++ WI +K M++A D T RD + + +
Sbjct: 2339 AELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASD-TGRDLEHCNALMRKLDDV 2397
Query: 3928 QSELAANKERLDQLKHAAINLGDDK--PEYHGTIDPQIEELATQWDELEKTTEEKGQKLF 4101
S++ + +R+ + A L + P ++D + ++ W +L+ L
Sbjct: 2398 DSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLG 2457
Query: 4102 DANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID 4281
AN ++ + + D + + M+ D DL V ++++ +E +M Q ID
Sbjct: 2458 GANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKID 2517
Query: 4282 XXXXXXXXXXXXHPDE-LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVD 4458
+P+ ++I+ + + LQA R+ L A +F DV
Sbjct: 2518 QHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVK 2577
Query: 4459 DEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEG 4638
+ +LW+++ + ++ DC + Q EI+ + + G++L
Sbjct: 2578 ELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRP 2637
Query: 4639 HANGP-AFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
P K + L Q L EA +R DL E+ + F + E W++ +E ++
Sbjct: 2638 QQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFL 2697
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
D+ G + + +KKH+ + + AD + L A+ +E + + I+ + A
Sbjct: 2698 NNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQKFANSILEGEPKDADLIREKLAY 2755
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
I + L + R + ++ +W+ K VA ++Y
Sbjct: 2756 ILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVA----LDENYREPSN 2811
Query: 5176 LQERFQQFAR-DTENI-GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLEL 5349
LQ + Q+ A D E + S RV + + LI H IA L W L
Sbjct: 2812 LQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGA 2871
Query: 5350 MDTRAQILEASRLLHKFYHDCRDCLSRIME-KTHAMPDDLGRDSSSVGALSRKHQNYLKD 5526
T+ L+ + F + + + E + +D G+D ++V L +KH+ D
Sbjct: 2872 SQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEAD 2931
Query: 5527 IAAIGEQVAQIERDAAELRDGYAGDKAL--DIGSRESEVVKAWRHLRGLCDARTSRLMDT 5700
+A GE Q+++ + + + L +I R + ++ + L R L D+
Sbjct: 2932 VAHHGELADQLKQKDEQF---FQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDS 2988
Query: 5701 SDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNAC 5880
L +F+ D L W+ E + SQ+ + V+ L H SL+AE+ ++E A
Sbjct: 2989 LSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQAL 3048
Query: 5881 ISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAE 6060
+ G+ ++ H+AS +++ K L + ++ R L +E F +A A+
Sbjct: 3049 LQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEAD 3108
Query: 6061 SWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
+W+ + P L S +YGR+ KK E ++ A + + KL T
Sbjct: 3109 AWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLAT 3159
Score = 354 bits (909), Expect = 1e-95
Identities = 394/1974 (19%), Positives = 817/1974 (40%), Gaps = 49/1974 (2%)
Frame = +1
Query: 886 LSSDLLEWINAKIQLLNERH-FENNLEGVQRQLTEF--NDYRTQEKPPKFDEKGELEVLL 1056
LS +L +N+ + LL + FEN+L ++ QL + R Q K P
Sbjct: 1948 LSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYP------------ 1995
Query: 1057 FTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR 1236
+N ++ K++A AW L+ ER + L L+
Sbjct: 1996 ---------SNASAIAQQQDKVVA----AWNDLK----ERSTARGDRLAASSDLQTFLT- 2037
Query: 1237 FNRKAEMRE--TWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXX 1410
++R+ +W + + + + +D + A +H+AI +I A E++
Sbjct: 2038 -----DVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNEL 2092
Query: 1411 XXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXX 1590
++ A + E+ + +++ LE + +
Sbjct: 2093 SDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLS 2152
Query: 1591 XXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSG 1770
++ L S D G + DV++ ++KH E I E+V+ ++ D +
Sbjct: 2153 SSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSAN 2212
Query: 1771 YKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQV 1950
+ + G + R V DL A R+ +LED +F D AE ++ I E+++
Sbjct: 2213 IQTILQGVLARRQKVK--------DLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKK 2264
Query: 1951 LSSTDTGRDIVT----VSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIP 2118
L + VT L KH+ + + + + + +G L + S I
Sbjct: 2265 LEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIK 2324
Query: 2119 PRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDE 2298
+ + + L R L + +F + D ++ ++ D ++ + D G+D
Sbjct: 2325 RAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDL 2384
Query: 2299 GTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDI----RQRLDTTLKQKA 2466
L++K DDV +++ DQ +K ++ A+ L +A+ D ++R D +
Sbjct: 2385 EHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWR- 2443
Query: 2467 ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFD 2646
+L+ + L A ++ D D I EK +++ GRD+ VE + R +
Sbjct: 2444 QLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREE 2503
Query: 2647 TLEQDMKNQEAKVTNVNDLARQLLNVEHPN--SDDILHRQNKLNARWAQLRDMVDQKRNE 2820
LE+DM + K+ ++ A + L ++P + I + +L+ W L+ + ++++
Sbjct: 2504 ALERDMSAVKQKIDQ-HETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSI 2562
Query: 2821 LERAHRLETFRIDCQETVTWIEDKTRVLED--SDALTNDLSGVMKLQRRLSMMERDLGAI 2994
L A+ F D +E W+ D + + + S + ND ++L + + ++
Sbjct: 2563 LNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKV---EIEGR 2619
Query: 2995 QAKLDSLHKEADDIERERPQEAQA--IREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
Q L ++ + + + RPQ+ Q +R+ + + ++ LN+ E L EA LQ
Sbjct: 2620 QEAFAGLKQQGEQLSK-RPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQL 2678
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
F ++ + WL + + +++ S E+LL +H + + +A+ ++ +
Sbjct: 2679 FKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQKFAN 2736
Query: 3349 RVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLS 3528
+ + + + +R++LA + ++L + + R+ L+Q LQ FLR + + L
Sbjct: 2737 SILEGEPKDADL-IREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLV 2795
Query: 3529 QQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKI 3708
Q+ +A D+ + ++++++H F + +N ++++V G++L + H+A D+I
Sbjct: 2796 QKLQ-VALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEI 2854
Query: 3709 HKKARNID----ERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDET 3876
++ + ++ + +GA++ K KL+ A F DE W++E ++ E
Sbjct: 2855 AQQVQLLEGDWLKLKGASQTKKD----KLQQAYDALAFNRSVDEFNNWMDEVELQLSSED 2910
Query: 3877 Y-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQ 4053
Y +D +++ +H+ ++++A + E DQLK + I + +
Sbjct: 2911 YGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRR 2970
Query: 4054 WDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK 4233
++ L + + + L D+ Q +++ D +W + + +D L +V +K
Sbjct: 2971 YNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKK 3030
Query: 4234 QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKA 4413
+ +E E+ + I + E ++ +Q+QL +L+ RR
Sbjct: 3031 HNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLR 3090
Query: 4414 LERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPW 4593
L + F + ++ W+ E+ + + + G QK L++L E+ +P
Sbjct: 3091 LLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPS 3150
Query: 4594 INQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDC 4773
I ++ LI+ H + +K ++ +++L K+R+ LGE +K ++L +
Sbjct: 3151 IEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRET 3210
Query: 4774 GEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE 4953
E W+ +Q ++ G+D + I E S+++ + A + + ++E
Sbjct: 3211 EELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQE 3270
Query: 4954 KSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVA 5133
+P I+ ++ + ++L+ L+D + R D+ +Q I +K+
Sbjct: 3271 NNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASL 3330
Query: 5134 GSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPT-IALWK 5310
S++ GQD E +Q L + Q F ++E +G + ++ +G + DA I + +
Sbjct: 3331 ISEDYGQDLESIQALGRKHQVF--ESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKR 3388
Query: 5311 DSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSV 5487
D EAW +L E R L + L ++ + RD ++ I E + +L +
Sbjct: 3389 DETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGA 3448
Query: 5488 GALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEV-VKAWRH--L 5658
L +++ +I E A+ + +L +K E ++ V RH L
Sbjct: 3449 ELLLASTKDHDTEIRTRDETFAKFAANGQQL----IKEKHFLAHEVEDKIKVLQARHELL 3504
Query: 5659 RGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSL 5838
+ + R D F+ L W+ + ++ + + VE L+ H+
Sbjct: 3505 KHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDF 3564
Query: 5839 KAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTT-ERAEMMRRWEDRWEYLQL 6015
+ + A+EE F A + R + + + ++K+ KL ER E R + + LQ
Sbjct: 3565 EKTVAAQEEKFQA---IKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQR 3621
Query: 6016 ILEV-------YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFA 6174
+ + ++ ++AA E P + + + ++ + F
Sbjct: 3622 LADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQL-----RPPFG 3676
Query: 6175 QEERFLALEKLTTFELKETQHRE---EETAKRRGPAHIG-SPSRSTPAAETSFGAQDDGA 6342
+ LAL+K ++ + + R + KR + ++ TP+ T AQ
Sbjct: 3677 DDNEHLALQKSSSSGMFGDRLRRGSADANVKRAESMKVQPKQAKRTPSFTTRRRAQSFRK 3736
Query: 6343 KQ-GEAFE-------GTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES 6498
Q GE F+ G+L RKH +S +KA RSW++ + VL + F+KD +
Sbjct: 3737 NQKGEGFDLPPVEIQGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQ 3796
Query: 6499 VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL 6660
P+ + G A DY KKK V L+LP G+E+LF+ S + + W+ ++
Sbjct: 3797 KTATAPVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKI 3850
Score = 326 bits (835), Expect = 6e-87
Identities = 355/1808 (19%), Positives = 727/1808 (39%), Gaps = 26/1808 (1%)
Frame = +1
Query: 814 QGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFN 993
Q ++ G + +E++ + + LL WI++ LN ++E L + N
Sbjct: 1170 QVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHN 1229
Query: 994 DYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIAD---INRAWQSLEKA 1164
D + + +EV+ Q + N V +L A+ I+R W A
Sbjct: 1230 DLGDDIRA---HDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGW-----A 1281
Query: 1165 EHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATK 1344
E ++ L+ +L FNR+A+ + ++ + +N G L VEA K
Sbjct: 1282 EKQKWLLQCVDL----------QMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILK 1331
Query: 1345 KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRV 1524
+H E + A ++ +++D I +R+ V R+
Sbjct: 1332 RHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKR 1391
Query: 1525 RLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE 1704
L+ S K F K+R+ ++ L ++ LQKH E ++
Sbjct: 1392 LLQASKDFHK-FAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEG 1450
Query: 1705 RVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNK 1884
++ N Q G+ VE D L KR+K+LL L+ ++ R+LE
Sbjct: 1451 QLRNVTKDGQALVQA----GNRVPEVESRVAD-----LNKRWKDLLTLSEDKGRKLEQAA 1501
Query: 1885 RLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLD 2064
+ + + + + E + L S D G D+ + L+ K + E+ + ++ + L
Sbjct: 1502 SQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELV 1561
Query: 2065 VSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDR 2244
+G ++ + NI E++ L++ + R+ +L + Y++F + D +
Sbjct: 1562 STGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQ 1621
Query: 2245 YLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP 2424
++ + L S ++G++ Q L KKH + E++ I +SL +++HP
Sbjct: 1622 WINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSL--ISQQHP 1679
Query: 2425 DIRQRLDTTLKQK----AELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLAT 2592
+ R+++++ +Q +LE R ++L +L + DA +ESW+ E+ +L +
Sbjct: 1680 E-REQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRS 1738
Query: 2593 LVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLN 2772
GRD + + + T+E ++ VT + ++ HP+S + +Q +
Sbjct: 1739 TEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIE 1798
Query: 2773 ARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL 2952
L + Q++ L + + ++ E WI ++ + D D + L
Sbjct: 1799 KMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSED-YGQDFEHLQLL 1857
Query: 2953 QRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREH 3132
Q + ++ + ++D A + A + + +++ W+ L + + +
Sbjct: 1858 QNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQR 1917
Query: 3133 EAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA-SEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E KL AG++ RF RD+ +A + A S+E + L A LL +H +G
Sbjct: 1918 EQKLHAAGEIHRFHRDV--AEALFRIQDKNAALSQELGRDLNSALALLRKH-------EG 1968
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMF------LRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
+ D + A + +D Q + + Q+ + W +L+ R L+
Sbjct: 1969 FENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAA 2028
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
+LQ FL D + S L ++ A +H ++A ++K R
Sbjct: 2029 SSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRY 2088
Query: 3652 VGMFGDQLCQDGHYAADKIHKK-ARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
+ D + Q GHYAA + +K A +DER+ + ++ + L+ + L FL D +
Sbjct: 2089 LNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKI-MLEQKIDLFCFLRDAKQ 2147
Query: 3829 LREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
+ + + + + + +K +H F+ + +E++ L+ L + +
Sbjct: 2148 IDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRH 2207
Query: 4006 EYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ----LEN 4173
I ++ + + +++ + KL DA +V+ A+ K W + LE
Sbjct: 2208 YDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEA 2267
Query: 4174 EMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHR 4353
+ + +L +QK + E+ I + IK
Sbjct: 2268 DAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAI 2327
Query: 4354 LAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
V E Q L A L+ R + LE + + +F +D + WI ++ ++ +A + G L C
Sbjct: 2328 EIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHC 2387
Query: 4534 HRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGH--ANGPAFEKKIQELRSAWQELKE 4707
+ L + L + +++ + + I +LI++ A+ + +K+ ++ W++L+
Sbjct: 2388 NALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQG 2447
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
A+ + LG + + H F D + ++E+ L M + G+D + + I++ E L+
Sbjct: 2448 ALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALER 2507
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPL--TEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXX 5061
D+ I T A +F+ +K P + I+ + ++ K + LQ
Sbjct: 2508 DMSAVKQKIDQHETAA-EFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEA 2566
Query: 5062 XXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVAN 5241
+ ++ +L W+ D + ++ + E Q+ + E E A
Sbjct: 2567 YLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEG-RQEAFAG 2625
Query: 5242 ANDGCDTLIGHGHTDAP-TIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
+ L P + + L E + L E RA+ L + L F
Sbjct: 2626 LKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQ 2685
Query: 5419 CLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYA 5595
+ K + DDLG ++V L +KH + K + A + V +++ A + +G
Sbjct: 2686 VEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEP 2743
Query: 5596 GDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMN 5775
D L I + + +++ + L L + R RL + L +F+ + ++ W+ + K ++
Sbjct: 2744 KDADL-IREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQ-KLQVA 2801
Query: 5776 SQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKL 5955
E ++ S ++ + H + AE+ + + I G L+ H+A EI +++ L
Sbjct: 2802 LDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLL 2861
Query: 5956 TTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKL 6135
+ ++ + + + LQ + F R +W+ E L S++YG++L L
Sbjct: 2862 EGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNL 2921
Query: 6136 IKKHEAFE 6159
+KKHE E
Sbjct: 2922 LKKHERLE 2929
Score = 249 bits (637), Expect = 5e-64
Identities = 285/1580 (18%), Positives = 623/1580 (39%), Gaps = 25/1580 (1%)
Frame = +1
Query: 1600 KSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKP 1779
K R++ D G V++ +K +D++ +RV FR G+
Sbjct: 997 KERMIKSDEGE---GVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRR------QGHSQ 1047
Query: 1780 VEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSS 1959
++ I R + + ++ L + A+R++ LE + F E + + E+ L +
Sbjct: 1048 LDK--IIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDT 1105
Query: 1960 TDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIR 2139
D+ TV L +H+N E L +E ++R+ G +++ DN+ R E++
Sbjct: 1106 AVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQ 1165
Query: 2140 DYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLL 2319
D ++++ + + R+ V F A + ++ +++++ +D T LL
Sbjct: 1166 DMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLL 1225
Query: 2320 KKHDDVHDELQNFD-QHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQ--L 2490
KKH+D+ D+++ D + ++V+ Q + P++ + + + KAE + + +
Sbjct: 1226 KKHNDLGDDIRAHDTEFVEVIQLG----KQLSDGKPNMAETVAVIERLKAEQDAIHRGWA 1281
Query: 2491 RKQR-LIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMK 2667
KQ+ L+ + L +AD +++ L G ++EVE + R E+ +
Sbjct: 1282 EKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLM 1341
Query: 2668 NQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLET 2847
Q+ + +D A +L++ +H +S I R+N++ + ++D +++ L+ +
Sbjct: 1342 AQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHK 1401
Query: 2848 FRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEA 3027
F + + W++DKTR+ D + DLS + + ++ ER+L A + +L ++ K+
Sbjct: 1402 FAAEADDLKVWLQDKTRIAGDEN--YRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDG 1459
Query: 3028 DDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLT 3207
+ + + + +++ W L + KL++A + R L+ + +
Sbjct: 1460 QALV-QAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVD 1518
Query: 3208 ATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMF 3387
+ S + L + L+N+ + EI + + ++ + GD D +
Sbjct: 1519 ELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGD----DMAHGGHFN 1574
Query: 3388 LRQRLAG---LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDD 3558
+ AG LQ+ +++L+ R+ L + LN F+ + +++ ++
Sbjct: 1575 AQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNE 1634
Query: 3559 IPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDER 3738
+ Q+L QA++ K+H+ + + I + G L H +++ + +++
Sbjct: 1635 LGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQA 1694
Query: 3739 RGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITSKFVR 3915
E +KL +L QQ+L D E+ W+ E + E RD + +
Sbjct: 1695 WQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTK 1754
Query: 3916 HQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQK 4095
H+ + EL + ++ H+ + + + + + L K ++ +
Sbjct: 1755 HKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGR 1814
Query: 4096 LFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQH 4275
L ++ + Y ++++W + E + ED D + + K ++ + A
Sbjct: 1815 LMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADR 1874
Query: 4276 IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDV 4455
+D ++ + ++ + L L+ R + L +F RDV
Sbjct: 1875 VDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDV 1934
Query: 4456 DDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDE 4635
+ I ++ A +Q LG L L + + N++ E + + + L +
Sbjct: 1935 AEALFRIQDKNA-ALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAK 1993
Query: 4636 GHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
+N A ++ ++ +AW +LKE R L S FL D + +W S +
Sbjct: 1994 YPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAAL 2053
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
+E D +H+ + +I+ D R L + V+ ++ + A
Sbjct: 2054 QAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAA 2113
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
+ L + R+ + + ++ S + GQ E VQ
Sbjct: 2114 MLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQN 2173
Query: 5176 LQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMD 5355
+ +F R + E+V+ + LI H D+ I + + + +L
Sbjct: 2174 KIRKHDEFERLIQT-QEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCA 2232
Query: 5356 TRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR-----KHQNYL 5520
R LE + L KF DC + I EK + D + + KHQ +
Sbjct: 2233 VRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQ 2292
Query: 5521 KDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDT 5700
++AA ++ +I+ D + + + +I V++AW+ L + R L +
Sbjct: 2293 AEVAANQGRIQEIQ-DTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEA 2351
Query: 5701 SDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNAC 5880
D +F + + + W+ + + + + + +D+ LM + +++ ++
Sbjct: 2352 QDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHI 2411
Query: 5881 ISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRR-WEDRWEYLQLIL-----------E 6024
L L+N+ + T+ + R+ + W LQ L E
Sbjct: 2412 NQLADKLINQAQ----------VPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANE 2461
Query: 6025 VYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
++ F RD + + + S + GR+L LI++ EA E+ A +++ E
Sbjct: 2462 IHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHET 2521
Query: 6205 LTTFELKETQHREEETAKRR 6264
F +K+ R + +R+
Sbjct: 2522 AAEFLIKKYPERGAQHIERK 2541
Score = 39.7 bits (91), Expect = 1.0
Identities = 48/213 (22%), Positives = 92/213 (42%), Gaps = 21/213 (9%)
Frame = +1
Query: 5686 RLMDTS-DLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSL----- 5838
+LMD ++ + +LL W+ + E+ ++ P + G++ L ++++
Sbjct: 270 QLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPK 329
Query: 5839 ---KAEIDAREENFNACISLGRDLLNRKHYAS------SEIEK--KLIKLTTERAEMMRR 5985
++EI+A N + LN+ Y ++IEK ++++ E+ R
Sbjct: 330 YKERSEIEALYFTINTLLKA----LNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALR 385
Query: 5986 WED-RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
E R E L+ + Y+F + + + E +L L Y R ++ T+K KHEA
Sbjct: 386 DELLRQEKLEQLN--YKFEKKSVLREGYLKEMIQVLSDPRYLRQVDATLK---KHEAISA 440
Query: 6163 SAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
A+ ERF L + +E H +E +R
Sbjct: 441 DILARVERFNDLTAMAEELDRENYHGKERVRRR 473
>gi|45552921|ref|NP_995987.1| CG12008-PC [Drosophila melanogaster]
gi|45445783|gb|AAS64957.1| CG12008-PC [Drosophila melanogaster]
Length = 4207
Score = 989 bits (2558), Expect = 0.0
Identities = 654/2211 (29%), Positives = 1074/2211 (47%), Gaps = 168/2211 (7%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGER 255
FE RIK L +ER +QKKTFTKW+NS L++ +V+DL+ D+ DG LL+LL ++S E+
Sbjct: 10 FENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEK 69
Query: 256 LPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQI 435
L KP G+MR+H +ENV K L FL + V LE++G+ DIVDGN RL LGLIWTIILRFQI
Sbjct: 70 LGKPNSGRMRVHKIENVNKSLAFLHTK-VRLESIGAEDIVDGNPRLILGLIWTIILRFQI 128
Query: 436 QDITF---EDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHR 606
Q+I E+ ++ E RSAK+ALLLWCQ KT GYP VN+ +F+ SWR GL FNALIH HR
Sbjct: 129 QEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHR 188
Query: 607 PDLVDYDNL--QKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
PDL +Y + K++ L NL AFDTA N+LG+ LDAED++ +PDEKSI+TYV +YY
Sbjct: 189 PDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYY 248
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
H F ++K + GKRI ++ +LM+ D+ +YE L+++LL WI K L +R N+L
Sbjct: 249 HTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSL 308
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
EG+QR+L F +YRT EKPPK+ E+ E+E L FT+ + ++A NQ P+ P++G+L+ DI +
Sbjct: 309 EGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEK 368
Query: 1141 AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDL 1320
AWQ LE AEH RE+ L++EL+RQEKLEQL +F +K+ +RE +L E +++S + L
Sbjct: 369 AWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRY---L 425
Query: 1321 SSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXX 1500
V+A KKHEAI DI A ER NYH + ++ R++ V
Sbjct: 426 RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLL 485
Query: 1501 XXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLE 1680
+R+ L + + ++ + SED+G HL+ VE+LLQ H+L E
Sbjct: 486 ELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQE 545
Query: 1681 SDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAER 1860
+N GE + QA +++ + D + + +R L++ Y ELL +A R
Sbjct: 546 LQVNTYGETLKRFNRQALPYKSSEHKDAA--------LLAQRLADLEEAYSELLRRSAAR 597
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
+ RLE+ + F D E + +++++ + T +D+ V L KHK E+ ++
Sbjct: 598 RARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSR 657
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
+ ++ +GK L E P S I R+ + ++ L+ L R+ +L E YQF+
Sbjct: 658 KPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFY 717
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
TDA++ + +L + + +++S D G DE + Q LL++H D+ EL + I L+ +A+ L
Sbjct: 718 TDANEAESWLNEKIALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKL 777
Query: 2401 PQEA----------REHPDIRQR---LDTTLKQK--------AELENLSQLRKQRLIDAL 2517
+ E P++ Q +T L K +LE+ + L
Sbjct: 778 IKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVK 837
Query: 2518 SLY--------------KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLE 2655
SL+ L + + W K + VP + EVE +
Sbjct: 838 SLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPK 897
Query: 2656 QDMKNQEAKVTNVNDLARQLLNVE----------------------HPNSDDILHRQNKL 2769
+ KV L RQ++ V+ + N+D + RQ ++
Sbjct: 898 AEKVKSLQKVKK-TILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRI 956
Query: 2770 NARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMK 2949
N + +L++M ++ LE + L F +C + W+++K R+++ + GV
Sbjct: 957 NQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEG-----EGVDN 1011
Query: 2950 LQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVRE 3129
+R+ DL A +++ + D R+ + I ++IHQ+W LN +
Sbjct: 1012 AKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQ 1071
Query: 3130 HEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E L+ A ++ F R D + W++ Q+ + L + L +H + E+
Sbjct: 1072 REKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAP 1131
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQM 3489
+ ++ +G+ V ++ + + R +Q+ W+++Q+ + ++ + + Q+
Sbjct: 1132 VEDKVNRVTYLGNSV-KNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQV 1190
Query: 3490 FLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGD 3669
F AK + ++ L D+ + +E A N LK+H D + A+D + V G
Sbjct: 1191 FNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGK 1250
Query: 3670 QLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL------ 3831
QL A+ + R E+ +R A E K L + LQ F + D++
Sbjct: 1251 QLSDGKPNMAETVAVIERLKAEQDAIHRGWA-EKQKWLLQCVDLQMFNREADKIDATTKS 1309
Query: 3832 ----------------------REWIEEKMIRAQDETYR---------------DAKTI- 3897
R EK + AQD+ + D+K I
Sbjct: 1310 HEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIG 1369
Query: 3898 --------TSKFVRHQAFQSE--LAANKE------RLDQLK----HAAINLGDDKPEYHG 4017
K V+ +AF+ + L A+K+ D LK GD+
Sbjct: 1370 DRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRDLS 1429
Query: 4018 TIDPQIE-------ELATQWDELEKTTEEKGQKLFDANRQQLYVQS-IADM-KEW----- 4155
+ +++ EL +L T++ GQ L A + V+S +AD+ K W
Sbjct: 1430 NLPRKLQKHQAFERELRANEGQLRNVTKD-GQALVQAGNRVPEVESRVADLNKRWKDLLT 1488
Query: 4156 ------------ATQLENEMTREDQP----------------GDLTTVNVAMQKQHLIET 4251
A+Q E+ + ED DL + + KQ ++E+
Sbjct: 1489 LSEDKGRKLEQAASQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILES 1548
Query: 4252 EMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
E+ Q + +NI+A +Q++ + L+ P RR LE
Sbjct: 1549 EITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLN 1608
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
+F ++D E WI+E L AK+ LG++L L K + L EI H+P IN+
Sbjct: 1609 YHKFVFELDSEFQWINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALV 1668
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
GQ LI + H E Q+L AWQ+L+ +R L S KA Q+L+D GE E+W
Sbjct: 1669 AGQSLISQQHPEREQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESW 1728
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+ E+ + E G+D S + KH+ ++ ++D ++ + + V P ++
Sbjct: 1729 LGERNNVLRSTEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSK 1788
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENG 5151
+ +Q IEK+ L + E D++ QWI ++E A S++ G
Sbjct: 1789 VLAAKQQLIEKMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYG 1848
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
QD+EH+Q+LQ +F E +G++RV LI A + ++ L +W
Sbjct: 1849 QDFEHLQLLQNKFDDLKHRVE-VGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSW 1907
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQ 5511
ENLL+L++ R Q L A+ +H+F+ D + L RI +K A+ +LGRD +S AL RKH+
Sbjct: 1908 ENLLQLLNQREQKLHAAGEIHRFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHE 1967
Query: 5512 NYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRL 5691
+ D+ A+ Q+ + D+ L+ Y + A I ++ +VV AW L+ AR RL
Sbjct: 1968 GFENDLVALEAQLQVLVEDSVRLQAKYPSN-ASAIAQQQDKVVAAWNDLKERSTARGDRL 2026
Query: 5692 MDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENF 5871
+SDL F+ VRD++ W ++ + ++E D +G L H ++ EI+ARE+ F
Sbjct: 2027 AASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKF 2086
Query: 5872 NACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAA 6051
L ++ HYA++++E+K + ER ++ W + L+ ++++ F RDA
Sbjct: 2087 RYLNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAK 2146
Query: 6052 VAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
++ +Q+ L S ++G+ +E+ I+KH+ FE+ QEE+ L++
Sbjct: 2147 QIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQE 2197
Score = 575 bits (1481), Expect = e-162
Identities = 437/1831 (23%), Positives = 827/1831 (44%), Gaps = 18/1831 (0%)
Frame = +1
Query: 811 IQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEF 990
+ +R G+++ L +++ + S ++ +WI + Q + + + E +Q +F
Sbjct: 1807 LASQRQGRLMESLYKHEYFLE-----SDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKF 1861
Query: 991 NDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEH 1170
+D + + + D + E+L L +++ P+ K + +W++L + +
Sbjct: 1862 DDLKHRVEVGA-DRVDQCELLAKKL-----IDSESPYANEVEKRQEQLRTSWENLLQLLN 1915
Query: 1171 ERELVLKEELIRQEKLEQLAA--RFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATK 1344
+RE +KL RF+R + + +SQ+ G DL+S A +
Sbjct: 1916 QRE----------QKLHAAGEIHRFHRDVAEALFRIQDKNAALSQE-LGRDLNSALALLR 1964
Query: 1345 KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRV 1524
KHE E D+ A E + + + I ++++ V AR
Sbjct: 1965 KHEGFENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGD 2024
Query: 1525 RLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE 1704
RL S +Q +++ L +E+ + L +H + +I +
Sbjct: 2025 RLAASSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEARED 2084
Query: 1705 R------VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKR 1866
+ +++S+ Q + D ++E+ + ++L ++K
Sbjct: 2085 KFRYLNELSDSMVQTGHYAAAD--------------VEEKCAAMLDERQKLHAAWNKKKI 2130
Query: 1867 RLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEK 2046
LE L F D ++++ Q+ LSS+D G+ + V + + KH E ++ E+
Sbjct: 2131 MLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEE 2190
Query: 2047 YLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTD 2226
+ L G++L ++ S NI L + K+K+L A R+ +L + Y +F D
Sbjct: 2191 KVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRD 2250
Query: 2227 ADDVDRYLYDTLRVMSSEDVGKDEGTVQ----LLLKKHDDVHDELQNFDQHIKVLHAKAE 2394
+ ++ + + + ++ E T L+KH E+ I+ +
Sbjct: 2251 CAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGV 2310
Query: 2395 SLPQEAREH-PDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDE 2571
L + E P+I++ ++ L+ L + R + L +A + S D +E+WI +
Sbjct: 2311 ILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRD 2370
Query: 2572 KGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSD--D 2745
K ++ GRD+E + + D ++ DM+ + +V ++N LA +L+N +D
Sbjct: 2371 KEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQS 2430
Query: 2746 ILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALT 2925
+ R+ N W QL+ ++ R L A+ + F D +T I +K+ + +D
Sbjct: 2431 VDKRRKDFNYNWRQLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDT-G 2489
Query: 2926 NDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQE-AQAIREDIKRIHQVW 3102
DL+ V L RR +ERD+ A++ K+D A+ + ++ P+ AQ I ++ +H+ W
Sbjct: 2490 RDLAAVEALIRREEALERDMSAVKQKIDQHETAAEFLIKKYPERGAQHIERKLEELHKSW 2549
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
L + ++ L+EA +F+ D+ + W+ +++ + + P ++ + E L H
Sbjct: 2550 GNLQALSVKRQSILNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELH 2609
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHL 3462
+ EI+G E + ++ G+++++ Q +R+ L L+E + L W R
Sbjct: 2610 QERKVEIEGRQEAFAGLKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARD 2669
Query: 3463 LSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEK 3642
L++ LQ+F +Q E+ L+ +E +L DD+ S E LK+H +F + A +
Sbjct: 2670 LTEAHQLQLFKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHA--DH 2727
Query: 3643 IRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDC 3822
+ + F + + + AD I +K I R+ E ++E ++L + LQ+FL
Sbjct: 2728 VDTLQKFANSILEGEPKDADLIREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSL 2787
Query: 3823 DELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDK 4002
E+ W+ +K+ A DE YR+ + SK +H AF +EL +N R+ + H L
Sbjct: 2788 YEIDRWLVQKLQVALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGD 2847
Query: 4003 PEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMT 4182
I Q++ L W +L+ ++ K KL A + +S+ + W ++E +++
Sbjct: 2848 HFAKDEIAQQVQLLEGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLS 2907
Query: 4183 REDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAV 4362
ED DL V+ ++K +E ++ + D I
Sbjct: 2908 SEDYGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVS 2967
Query: 4363 QEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRL 4542
+ L PL RR+ LE + QF RD +DE W++E+ ++A +Q+LG SL L
Sbjct: 2968 IRRYNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGL 3027
Query: 4543 QKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDR 4722
QK L E+ + EP I + GQ++I + H + K + L+ +L++ R
Sbjct: 3028 QKKHNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIR 3087
Query: 4723 KGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKF 4902
+ L ++ ++ F + EA+AWM E+ + + G+DE S + KK E LQ ++ F
Sbjct: 3088 RLRLLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAF 3147
Query: 4903 ADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALH 5082
+I +A A +E + I + AQ+ + Y L +
Sbjct: 3148 KPSIEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYL 3207
Query: 5083 REIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDT 5262
RE ++L +W+ D+ V S++ G+D EHV+ L F+ F + N RV + D
Sbjct: 3208 RETEELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNL-NANEARVEACLERGDR 3266
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
LI + +I +D + WE L +L+ R L ++ +H + + + I EK
Sbjct: 3267 LIQENNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEK 3326
Query: 5443 THAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
++ +D G+D S+ AL RKHQ + ++ I QV + +AA+L + Y K I
Sbjct: 3327 DASLISEDYGQDLESIQALGRKHQVFESELVGIQGQVDSVLAEAAKLGEIYPDAKE-HIE 3385
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
+ E V+AW L+ AR ++L L + + RDL+ W++E+ ++ + E V
Sbjct: 3386 VKRDETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSV 3445
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
+G ELL+ + + EI R+E F + G+ L+ KH+ + E+E K IK+ R E++
Sbjct: 3446 AGAELLLASTKDHDTEIRTRDETFAKFAANGQQLIKEKHFLAHEVEDK-IKVLQARHELL 3504
Query: 5980 RRW-EDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAF 6156
+ R E +L L+ F +DA + E W+ ++EP L + G ++ + L+++HE F
Sbjct: 3505 KHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDF 3564
Query: 6157 EKSAFAQEERFLALEKLTTFELKETQHREEE 6249
EK+ AQEE+F A++++T E E+E
Sbjct: 3565 EKTVAAQEEKFQAIKRITMLEQLFRHQLEQE 3595
Score = 392 bits (1006), Expect = e-107
Identities = 348/1705 (20%), Positives = 705/1705 (40%), Gaps = 23/1705 (1%)
Frame = +1
Query: 1117 KLIA---DINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQR 1287
K+IA I++ WQ L A+ +RE L+ FNR + + W++E
Sbjct: 1050 KIIARQRQIHQIWQRLNNAKAQREKSLEGA--------SSVELFNRTCDEAKVWMSEKML 1101
Query: 1288 LVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERK 1467
+ DL +V+A ++H+ +E ++ E++ ++ +N R+
Sbjct: 1102 QLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQ 1161
Query: 1468 ENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDV 1647
+ V R R+E + Q + +K +L +++ +
Sbjct: 1162 QEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETA 1221
Query: 1648 EDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKR 1827
+LL+KH L DI I ++ DG + D + +
Sbjct: 1222 NNLLKKHNDLGDDIRAHDTEFVEVIQLGKQL--SDGKPNMAETVAVIERLKAEQDAIHRG 1279
Query: 1828 YKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAK 2007
+ AE+++ L L F + +++ K E L + G + V +L +
Sbjct: 1280 W-------AEKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKR 1332
Query: 2008 HKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKER 2187
H + E +L +K L + +L S I R ++ +K+ + RK
Sbjct: 1333 HLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRL 1392
Query: 2188 LAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQH 2367
L ++++F +ADD+ +L D R+ E+ +D + L+KH EL+ +
Sbjct: 1393 LQASKDFHKFAAEADDLKVWLQDKTRIAGDENY-RDLSNLPRKLQKHQAFERELRANEGQ 1451
Query: 2368 IKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDAD 2547
++ + ++L Q P++ R+ K+ +L LS+ + ++L A S + +
Sbjct: 1452 LRNVTKDGQALVQAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLE 1511
Query: 2548 SVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE 2727
+ +DE L + G D+ + + ++ LE ++ + KV + + +
Sbjct: 1512 DAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGG 1571
Query: 2728 HPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
H N+ +I +L R+ LRD ++R +LE + F + WI + +
Sbjct: 1572 HFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAK 1631
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKR 3087
S+ L +L L ++ +E ++ Q ++ + ++ E + + ++
Sbjct: 1632 -SNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQ 1690
Query: 3088 IHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQ 3267
+ Q W L + E KLD + Q++L D ++WL + S E + A +
Sbjct: 1691 LEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAK 1750
Query: 3268 LLNQHAAIREEIDGYAEDYKKM-RAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMW 3444
LL +H I E+D Y+ +M + V + D + + +Q+L +++ + L ++
Sbjct: 1751 LLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQL--IEKMLKSLHKLA 1808
Query: 3445 DNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTM 3624
RQ L + L + ++ + E + +QE + +D Q E + + D +
Sbjct: 1809 SQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRV 1868
Query: 3625 DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQ 3804
+ +++ + +L A+++ K+ + + + +KL A +
Sbjct: 1869 EVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIH 1928
Query: 3805 QFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAI 3984
+F D E I++K E RD + + +H+ F+++L A + +L L ++
Sbjct: 1929 RFHRDVAEALFRIQDKNAALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSV 1988
Query: 3985 NLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ 4164
L P I Q +++ W++L++ + +G +L ++ Q ++ + D+ W++
Sbjct: 1989 RLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSN 2048
Query: 4165 LENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIK 4344
L + E+ D + I E+ + +++
Sbjct: 2049 LRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVE 2108
Query: 4345 AHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESL 4524
A+ ++ Q+L A + ++ LE+K F F RD S + + + G+++
Sbjct: 2109 EKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTV 2168
Query: 4525 PDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELK 4704
D + I E ++ + +G++LI++ H + + +Q + + Q++K
Sbjct: 2169 EDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVK 2228
Query: 4705 EAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ----IKKH 4872
+ R+ L ++ +F+ DC EA+ W++E++ + D E + ++ ++KH
Sbjct: 2229 DLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKH 2288
Query: 4873 ERLQSD-------IDKFADTIRALATKAHKFVEEKSPLTEQI----QVRQAQIEKLYAGL 5019
+ Q++ I + DT L +K H+ E E + Q A++E+ GL
Sbjct: 2289 QAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGL 2348
Query: 5020 QDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQF 5199
++ + ++D + WI DKE++ + + G+D EH L +
Sbjct: 2349 EE-----------AQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDV 2397
Query: 5200 ARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWK--DSLNEAWENLLELMDTRAQIL 5373
D + +RV + N D LI A T ++ K N W L ++ +L
Sbjct: 2398 DSDM-RVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALL 2456
Query: 5374 EASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQV 5550
+ +H F D D RI EK+ AM D GRD ++V AL R+ + +D++A+ +++
Sbjct: 2457 GGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKI 2516
Query: 5551 AQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMV 5730
Q E A L Y A I + E+ K+W +L+ L R S L + KF++ V
Sbjct: 2517 DQHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDV 2576
Query: 5731 RDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR 5910
++L LW++++ ++MN+ + P ++ E + HQ K EI+ R+E F G L R
Sbjct: 2577 KELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKR 2636
Query: 5911 -KHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPY 6087
+ + K L+ L + W +R L ++ F E WL +E +
Sbjct: 2637 PQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAF 2696
Query: 6088 LISKEYGRNLEETIKLIKKHEAFEK 6162
L + + G + +L+KKH+ FEK
Sbjct: 2697 LNNDDLGDSYTAVERLLKKHDEFEK 2721
Score = 368 bits (945), Expect = e-99
Identities = 388/1851 (20%), Positives = 787/1851 (41%), Gaps = 40/1851 (2%)
Frame = +1
Query: 781 HYFNKL---KQDNIQGKRIGKVINE-------LMENDKMINRYETLSSDLLEWINAKIQL 930
HY +K +++ + GKR K + + L++ K +++ + DL W+ K ++
Sbjct: 1362 HYDSKYIGDRRNQVLGKR--KAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRI 1419
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
+ ++ + L + R+L + + + + +G+L + Q+ ++A N+ VP
Sbjct: 1420 AGDENYRD-LSNLPRKLQKHQAFERELRA----NEGQLRNVTKDGQALVQAGNR---VPE 1471
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR--FNRKAEMRETWLTENQ 1284
+AD+N+ W+ L L L E+ + KLEQ A++ NR E + + E
Sbjct: 1472 VESRVADLNKRWKDL--------LTLSED--KGRKLEQAASQREHNRSLEDAKKKVDELD 1521
Query: 1285 RLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINER 1464
+ + GNDL S + K + +E++I ++++ + + I
Sbjct: 1522 SALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAG 1581
Query: 1465 KENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMD 1644
+ + RR +LE S+ K S +LG +L
Sbjct: 1582 TKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNELGQNLHQ 1641
Query: 1645 VEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQK 1824
+ L +KH LE++I +N ++ Q + P E ++ L++
Sbjct: 1642 AQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHP--------EREQVESLCQQLEQ 1693
Query: 1825 RYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLA 2004
+++L ER R+L+ + + Q+ +D E+E + E+ VL ST+ GRD + + LL
Sbjct: 1694 AWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLT 1753
Query: 2005 KHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKE 2184
KHK E L + + S + + P S + + I + L +L++ R+
Sbjct: 1754 KHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQG 1813
Query: 2185 RLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQ 2364
RL + +++F ++D+V++++ + + SSED G+D +QLL K DD+ ++
Sbjct: 1814 RLMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGAD 1873
Query: 2365 HIKVLHAKAESL-PQEAREHPDIRQRLDTTLKQKAELENLSQL---RKQRLIDALSLYKL 2532
+ A+ L E+ ++ +R + + + ENL QL R+Q+L A +++
Sbjct: 1874 RVDQCELLAKKLIDSESPYANEVEKRQE---QLRTSWENLLQLLNQREQKLHAAGEIHRF 1930
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKV-TNVNDLAR 2709
+ D I +K L+ + GRD+ + + + E D+ EA++ V D R
Sbjct: 1931 HRDVAEALFRIQDKNAALSQEL-GRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVR 1989
Query: 2710 QLLNVEHP-NSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIE 2886
L ++P N+ I +Q+K+ A W L++ + + L + L+TF D ++ V+W
Sbjct: 1990 --LQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSS 2047
Query: 2887 DKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIER-------E 3045
+ L+ ++ +D +G L+ + + ++ A + K L++ +D + + +
Sbjct: 2048 NLRAALQ-AEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAAD 2106
Query: 3046 RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV 3225
++ A+ ++ +++H W NKK + L++ DL FLRD ++ Q +
Sbjct: 2107 VEEKCAAMLDERQKLHAAW---NKK----KIMLEQKIDLFCFLRDAKQIDNLSSSQQAAL 2159
Query: 3226 ASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLA 3405
+S + Q++ + + + +H I E ++ G ++ +Q ++ L
Sbjct: 2160 SSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLI-EQRHYDSANIQTILQ 2218
Query: 3406 GLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIP----QSL 3573
G+ ++++ + R++ L L F+RD +A+ +++++ L D +L
Sbjct: 2219 GVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNL 2278
Query: 3574 EQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANR 3753
++ +L++HQ F + AN +I+ + G L H ++ +I + + E
Sbjct: 2279 DEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAIEIVLEAWQGLL 2338
Query: 3754 EKAQEVLKKLKDALSLQQFLSDCDELREWIEEK--MIRAQDETYRDAKTITSKFVRHQAF 3927
+ ++ + L++A +F S D++ WI +K M++A D T RD + + +
Sbjct: 2339 AELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASD-TGRDLEHCNALMRKLDDV 2397
Query: 3928 QSELAANKERLDQLKHAAINLGDDK--PEYHGTIDPQIEELATQWDELEKTTEEKGQKLF 4101
S++ + +R+ + A L + P ++D + ++ W +L+ L
Sbjct: 2398 DSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQGALNAYRALLG 2457
Query: 4102 DANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID 4281
AN ++ + + D + + M+ D DL V ++++ +E +M Q ID
Sbjct: 2458 GANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKID 2517
Query: 4282 XXXXXXXXXXXXHPDE-LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVD 4458
+P+ ++I+ + + LQA R+ L A +F DV
Sbjct: 2518 QHETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEAYLAHKFVSDVK 2577
Query: 4459 DEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEG 4638
+ +LW+++ + ++ DC + Q EI+ + + G++L
Sbjct: 2578 ELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEGRQEAFAGLKQQGEQLSKRP 2637
Query: 4639 HANGP-AFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
P K + L Q L EA +R DL E+ + F + E W++ +E ++
Sbjct: 2638 QQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQVEIWLANKEAFL 2697
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
D+ G + + +KKH+ + + AD + L A+ +E + + I+ + A
Sbjct: 2698 NNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQKFANSILEGEPKDADLIREKLAY 2755
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
I + L + R + ++ +W+ K VA ++Y
Sbjct: 2756 ILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQKLQVA----LDENYREPSN 2811
Query: 5176 LQERFQQFAR-DTENI-GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLEL 5349
LQ + Q+ A D E + S RV + + LI H IA L W L
Sbjct: 2812 LQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLLEGDWLKLKGA 2871
Query: 5350 MDTRAQILEASRLLHKFYHDCRDCLSRIME-KTHAMPDDLGRDSSSVGALSRKHQNYLKD 5526
T+ L+ + F + + + E + +D G+D ++V L +KH+ D
Sbjct: 2872 SQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNLLKKHERLEAD 2931
Query: 5527 IAAIGEQVAQIERDAAELRDGYAGDKAL--DIGSRESEVVKAWRHLRGLCDARTSRLMDT 5700
+A GE Q+++ + + + L +I R + ++ + L R L D+
Sbjct: 2932 VAHHGELADQLKQKDEQF---FQAEHFLRHEIHERATVSIRRYNTLHEPLGIRRENLEDS 2988
Query: 5701 SDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNAC 5880
L +F+ D L W+ E + SQ+ + V+ L H SL+AE+ ++E A
Sbjct: 2989 LSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKKHNSLEAELTSQEPLIQAL 3048
Query: 5881 ISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAE 6060
+ G+ ++ H+AS +++ K L + ++ R L +E F +A A+
Sbjct: 3049 LQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLRLLDAVESQLFYVEANEAD 3108
Query: 6061 SWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
+W+ + P L S +YGR+ KK E ++ A + + KL T
Sbjct: 3109 AWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPSIEKVAKLAT 3159
Score = 354 bits (909), Expect = 1e-95
Identities = 394/1974 (19%), Positives = 817/1974 (40%), Gaps = 49/1974 (2%)
Frame = +1
Query: 886 LSSDLLEWINAKIQLLNERH-FENNLEGVQRQLTEF--NDYRTQEKPPKFDEKGELEVLL 1056
LS +L +N+ + LL + FEN+L ++ QL + R Q K P
Sbjct: 1948 LSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAKYP------------ 1995
Query: 1057 FTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR 1236
+N ++ K++A AW L+ ER + L L+
Sbjct: 1996 ---------SNASAIAQQQDKVVA----AWNDLK----ERSTARGDRLAASSDLQTFLT- 2037
Query: 1237 FNRKAEMRE--TWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXX 1410
++R+ +W + + + + +D + A +H+AI +I A E++
Sbjct: 2038 -----DVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNEL 2092
Query: 1411 XXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXX 1590
++ A + E+ + +++ LE + +
Sbjct: 2093 SDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLS 2152
Query: 1591 XXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSG 1770
++ L S D G + DV++ ++KH E I E+V+ ++ D +
Sbjct: 2153 SSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRHYDSAN 2212
Query: 1771 YKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQV 1950
+ + G + R V DL A R+ +LED +F D AE ++ I E+++
Sbjct: 2213 IQTILQGVLARRQKVK--------DLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKK 2264
Query: 1951 LSSTDTGRDIVT----VSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIP 2118
L + VT L KH+ + + + + + +G L + S I
Sbjct: 2265 LEADAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIK 2324
Query: 2119 PRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDE 2298
+ + + L R L + +F + D ++ ++ D ++ + D G+D
Sbjct: 2325 RAIEIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDL 2384
Query: 2299 GTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDI----RQRLDTTLKQKA 2466
L++K DDV +++ DQ +K ++ A+ L +A+ D ++R D +
Sbjct: 2385 EHCNALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWR- 2443
Query: 2467 ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFD 2646
+L+ + L A ++ D D I EK +++ GRD+ VE + R +
Sbjct: 2444 QLQGALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREE 2503
Query: 2647 TLEQDMKNQEAKVTNVNDLARQLLNVEHPN--SDDILHRQNKLNARWAQLRDMVDQKRNE 2820
LE+DM + K+ ++ A + L ++P + I + +L+ W L+ + ++++
Sbjct: 2504 ALERDMSAVKQKIDQ-HETAAEFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSI 2562
Query: 2821 LERAHRLETFRIDCQETVTWIEDKTRVLED--SDALTNDLSGVMKLQRRLSMMERDLGAI 2994
L A+ F D +E W+ D + + + S + ND ++L + + ++
Sbjct: 2563 LNEAYLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKV---EIEGR 2619
Query: 2995 QAKLDSLHKEADDIERERPQEAQA--IREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
Q L ++ + + + RPQ+ Q +R+ + + ++ LN+ E L EA LQ
Sbjct: 2620 QEAFAGLKQQGEQLSK-RPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQL 2678
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
F ++ + WL + + +++ S E+LL +H + + +A+ ++ +
Sbjct: 2679 FKAQVEQVEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLL--HADHVDTLQKFAN 2736
Query: 3349 RVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLS 3528
+ + + + +R++LA + ++L + + R+ L+Q LQ FLR + + L
Sbjct: 2737 SILEGEPKDADL-IREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLV 2795
Query: 3529 QQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKI 3708
Q+ +A D+ + ++++++H F + +N ++++V G++L + H+A D+I
Sbjct: 2796 QKLQ-VALDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEI 2854
Query: 3709 HKKARNID----ERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDET 3876
++ + ++ + +GA++ K KL+ A F DE W++E ++ E
Sbjct: 2855 AQQVQLLEGDWLKLKGASQTKKD----KLQQAYDALAFNRSVDEFNNWMDEVELQLSSED 2910
Query: 3877 Y-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQ 4053
Y +D +++ +H+ ++++A + E DQLK + I + +
Sbjct: 2911 YGKDLAAVSNLLKKHERLEADVAHHGELADQLKQKDEQFFQAEHFLRHEIHERATVSIRR 2970
Query: 4054 WDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK 4233
++ L + + + L D+ Q +++ D +W + + +D L +V +K
Sbjct: 2971 YNTLHEPLGIRRENLEDSLSLQQFLRDAEDELQWLAEKQLVAGSQDLGTSLLSVQGLQKK 3030
Query: 4234 QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKA 4413
+ +E E+ + I + E ++ +Q+QL +L+ RR
Sbjct: 3031 HNSLEAELTSQEPLIQALLQRGQQMIRDNHFASEQLQYKSELLQKQLVQLRDLAAIRRLR 3090
Query: 4414 LERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPW 4593
L + F + ++ W+ E+ + + + G QK L++L E+ +P
Sbjct: 3091 LLDAVESQLFYVEANEADAWMREKRPVLSSSDYGRDEVSVQGHQKKLEVLQRELTAFKPS 3150
Query: 4594 INQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDC 4773
I ++ LI+ H + +K ++ +++L K+R+ LGE +K ++L +
Sbjct: 3151 IEKVAKLATGLIERNHFDSSNIAEKNAQVGQEYEDLLRLAKERESRLGECKKLFEYLRET 3210
Query: 4774 GEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE 4953
E W+ +Q ++ G+D + I E S+++ + A + + ++E
Sbjct: 3211 EELHEWVGDQMAVTASEDYGEDVEHVEQLILAFESFVSNLNANEARVEACLERGDRLIQE 3270
Query: 4954 KSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVA 5133
+P I+ ++ + ++L+ L+D + R D+ +Q I +K+
Sbjct: 3271 NNPYRSSIKSKRDETKQLWEELKDLVHARQDALAGAKQVHVYDRVADETIQLINEKDASL 3330
Query: 5134 GSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPT-IALWK 5310
S++ GQD E +Q L + Q F ++E +G + ++ +G + DA I + +
Sbjct: 3331 ISEDYGQDLESIQALGRKHQVF--ESELVGIQGQVDSVLAEAAKLGEIYPDAKEHIEVKR 3388
Query: 5311 DSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSV 5487
D EAW +L E R L + L ++ + RD ++ I E + +L +
Sbjct: 3389 DETVEAWTDLKEKTAARKNKLSQAEQLQSYFDEYRDLIAWINEMLAKITAPELANSVAGA 3448
Query: 5488 GALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEV-VKAWRH--L 5658
L +++ +I E A+ + +L +K E ++ V RH L
Sbjct: 3449 ELLLASTKDHDTEIRTRDETFAKFAANGQQL----IKEKHFLAHEVEDKIKVLQARHELL 3504
Query: 5659 RGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSL 5838
+ + R D F+ L W+ + ++ + + VE L+ H+
Sbjct: 3505 KHTLNKRREIYELNLDTQLFLKDAEILEQWISSREPQLKDTKLGDSIPQVEDLLRRHEDF 3564
Query: 5839 KAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTT-ERAEMMRRWEDRWEYLQL 6015
+ + A+EE F A + R + + + ++K+ KL ER E R + + LQ
Sbjct: 3565 EKTVAAQEEKFQA---IKRITMLEQLFRHQLEQEKISKLQEKERLEKERLEQLKQRELQR 3621
Query: 6016 ILEV-------YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFA 6174
+ + ++ ++AA E P + + + ++ + F
Sbjct: 3622 LADERRRAEKQHEHRQNAASQEKTPIFSSPMVTPAQTSGPQSPALSQVQL-----RPPFG 3676
Query: 6175 QEERFLALEKLTTFELKETQHRE---EETAKRRGPAHIG-SPSRSTPAAETSFGAQDDGA 6342
+ LAL+K ++ + + R + KR + ++ TP+ T AQ
Sbjct: 3677 DDNEHLALQKSSSSGMFGDRLRRGSADANVKRAESMKVQPKQAKRTPSFTTRRRAQSFRK 3736
Query: 6343 KQ-GEAFE-------GTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDES 6498
Q GE F+ G+L RKH +S +KA RSW++ + VL + F+KD +
Sbjct: 3737 NQKGEGFDLPPVEIQGSLERKHGLQSGGKKAPVRSWKQFHTVLCGQLVCFFKDENDFLQQ 3796
Query: 6499 VHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTEL 6660
P+ + G A DY KKK V L+LP G+E+LF+ S + + W+ ++
Sbjct: 3797 KTATAPVNILGAKCERADDYTKKKYVFRLKLPDGSEFLFEAPSLDILNDWVRKI 3850
Score = 326 bits (835), Expect = 6e-87
Identities = 355/1808 (19%), Positives = 727/1808 (39%), Gaps = 26/1808 (1%)
Frame = +1
Query: 814 QGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFN 993
Q ++ G + +E++ + + LL WI++ LN ++E L + N
Sbjct: 1170 QVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHN 1229
Query: 994 DYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIAD---INRAWQSLEKA 1164
D + + +EV+ Q + N V +L A+ I+R W A
Sbjct: 1230 DLGDDIRA---HDTEFVEVIQLGKQLSDGKPNMAETVAVIERLKAEQDAIHRGW-----A 1281
Query: 1165 EHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATK 1344
E ++ L+ +L FNR+A+ + ++ + +N G L VEA K
Sbjct: 1282 EKQKWLLQCVDL----------QMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILK 1331
Query: 1345 KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRV 1524
+H E + A ++ +++D I +R+ V R+
Sbjct: 1332 RHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKR 1391
Query: 1525 RLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE 1704
L+ S K F K+R+ ++ L ++ LQKH E ++
Sbjct: 1392 LLQASKDFHK-FAAEADDLKVWLQDKTRIAGDENYRDLSNLPRKLQKHQAFERELRANEG 1450
Query: 1705 RVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNK 1884
++ N Q G+ VE D L KR+K+LL L+ ++ R+LE
Sbjct: 1451 QLRNVTKDGQALVQA----GNRVPEVESRVAD-----LNKRWKDLLTLSEDKGRKLEQAA 1501
Query: 1885 RLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLD 2064
+ + + + + E + L S D G D+ + L+ K + E+ + ++ + L
Sbjct: 1502 SQREHNRSLEDAKKKVDELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELV 1561
Query: 2065 VSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDR 2244
+G ++ + NI E++ L++ + R+ +L + Y++F + D +
Sbjct: 1562 STGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQ 1621
Query: 2245 YLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP 2424
++ + L S ++G++ Q L KKH + E++ I +SL +++HP
Sbjct: 1622 WINEHLPAAKSNELGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSL--ISQQHP 1679
Query: 2425 DIRQRLDTTLKQK----AELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLAT 2592
+ R+++++ +Q +LE R ++L +L + DA +ESW+ E+ +L +
Sbjct: 1680 E-REQVESLCQQLEQAWQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRS 1738
Query: 2593 LVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLN 2772
GRD + + + T+E ++ VT + ++ HP+S + +Q +
Sbjct: 1739 TEYGRDRDSAAKLLTKHKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIE 1798
Query: 2773 ARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL 2952
L + Q++ L + + ++ E WI ++ + D D + L
Sbjct: 1799 KMLKSLHKLASQRQGRLMESLYKHEYFLESDEVEQWIREQEQAASSED-YGQDFEHLQLL 1857
Query: 2953 QRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREH 3132
Q + ++ + ++D A + A + + +++ W+ L + + +
Sbjct: 1858 QNKFDDLKHRVEVGADRVDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQR 1917
Query: 3133 EAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA-SEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E KL AG++ RF RD+ +A + A S+E + L A LL +H +G
Sbjct: 1918 EQKLHAAGEIHRFHRDV--AEALFRIQDKNAALSQELGRDLNSALALLRKH-------EG 1968
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMF------LRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
+ D + A + +D Q + + Q+ + W +L+ R L+
Sbjct: 1969 FENDLVALEAQLQVLVEDSVRLQAKYPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAA 2028
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
+LQ FL D + S L ++ A +H ++A ++K R
Sbjct: 2029 SSDLQTFLTDVRDIVSWSSNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRY 2088
Query: 3652 VGMFGDQLCQDGHYAADKIHKK-ARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
+ D + Q GHYAA + +K A +DER+ + ++ + L+ + L FL D +
Sbjct: 2089 LNELSDSMVQTGHYAAADVEEKCAAMLDERQKLHAAWNKKKI-MLEQKIDLFCFLRDAKQ 2147
Query: 3829 LREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
+ + + + + + +K +H F+ + +E++ L+ L + +
Sbjct: 2148 IDNLSSSQQAALSSSDFGQTVEDVQNKIRKHDEFERLIQTQEEKVSLLQEHGRKLIEQRH 2207
Query: 4006 EYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ----LEN 4173
I ++ + + +++ + KL DA +V+ A+ K W + LE
Sbjct: 2208 YDSANIQTILQGVLARRQKVKDLCAVRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEA 2267
Query: 4174 EMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHR 4353
+ + +L +QK + E+ I + IK
Sbjct: 2268 DAASYAEVTNLDEKIKKLQKHQAFQAEVAANQGRIQEIQDTGVILLSKQHESSPEIKRAI 2327
Query: 4354 LAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
V E Q L A L+ R + LE + + +F +D + WI ++ ++ +A + G L C
Sbjct: 2328 EIVLEAWQGLLAELEQRGRGLEEAQDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHC 2387
Query: 4534 HRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGH--ANGPAFEKKIQELRSAWQELKE 4707
+ L + L + +++ + + I +LI++ A+ + +K+ ++ W++L+
Sbjct: 2388 NALMRKLDDVDSDMRVDDQRVKHINQLADKLINQAQVPADTQSVDKRRKDFNYNWRQLQG 2447
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
A+ + LG + + H F D + ++E+ L M + G+D + + I++ E L+
Sbjct: 2448 ALNAYRALLGGANEIHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALER 2507
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPL--TEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXX 5061
D+ I T A +F+ +K P + I+ + ++ K + LQ
Sbjct: 2508 DMSAVKQKIDQHETAA-EFLIKKYPERGAQHIERKLEELHKSWGNLQALSVKRQSILNEA 2566
Query: 5062 XXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVAN 5241
+ ++ +L W+ D + ++ + E Q+ + E E A
Sbjct: 2567 YLAHKFVSDVKELELWVNDMIKKMNNTQSPSTINDCETQLELHQERKVEIEG-RQEAFAG 2625
Query: 5242 ANDGCDTLIGHGHTDAP-TIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
+ L P + + L E + L E RA+ L + L F
Sbjct: 2626 LKQQGEQLSKRPQQQQPDNVRKYLLVLEELHQTLNEAWSERARDLTEAHQLQLFKAQVEQ 2685
Query: 5419 CLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYA 5595
+ K + DDLG ++V L +KH + K + A + V +++ A + +G
Sbjct: 2686 VEIWLANKEAFLNNDDLGDSYTAVERLLKKHDEFEKLLHA--DHVDTLQKFANSILEGEP 2743
Query: 5596 GDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMN 5775
D L I + + +++ + L L + R RL + L +F+ + ++ W+ + K ++
Sbjct: 2744 KDADL-IREKLAYILRRKQKLLELSEERKQRLTQSHQLQEFLRSLYEIDRWLVQ-KLQVA 2801
Query: 5776 SQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKL 5955
E ++ S ++ + H + AE+ + + I G L+ H+A EI +++ L
Sbjct: 2802 LDENYREPSNLQSKIQKHAAFDAELLSNSPRVQSVIHEGERLIRGDHFAKDEIAQQVQLL 2861
Query: 5956 TTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKL 6135
+ ++ + + + LQ + F R +W+ E L S++YG++L L
Sbjct: 2862 EGDWLKLKGASQTKKDKLQQAYDALAFNRSVDEFNNWMDEVELQLSSEDYGKDLAAVSNL 2921
Query: 6136 IKKHEAFE 6159
+KKHE E
Sbjct: 2922 LKKHERLE 2929
Score = 249 bits (637), Expect = 5e-64
Identities = 285/1580 (18%), Positives = 623/1580 (39%), Gaps = 25/1580 (1%)
Frame = +1
Query: 1600 KSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKP 1779
K R++ D G V++ +K +D++ +RV FR G+
Sbjct: 997 KERMIKSDEGE---GVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRR------QGHSQ 1047
Query: 1780 VEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSS 1959
++ I R + + ++ L + A+R++ LE + F E + + E+ L +
Sbjct: 1048 LDK--IIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDT 1105
Query: 1960 TDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIR 2139
D+ TV L +H+N E L +E ++R+ G +++ DN+ R E++
Sbjct: 1106 AVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQ 1165
Query: 2140 DYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLL 2319
D ++++ + + R+ V F A + ++ +++++ +D T LL
Sbjct: 1166 DMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLL 1225
Query: 2320 KKHDDVHDELQNFD-QHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQ--L 2490
KKH+D+ D+++ D + ++V+ Q + P++ + + + KAE + + +
Sbjct: 1226 KKHNDLGDDIRAHDTEFVEVIQLG----KQLSDGKPNMAETVAVIERLKAEQDAIHRGWA 1281
Query: 2491 RKQR-LIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMK 2667
KQ+ L+ + L +AD +++ L G ++EVE + R E+ +
Sbjct: 1282 EKQKWLLQCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLM 1341
Query: 2668 NQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLET 2847
Q+ + +D A +L++ +H +S I R+N++ + ++D +++ L+ +
Sbjct: 1342 AQDKILKGFSDNADKLISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHK 1401
Query: 2848 FRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEA 3027
F + + W++DKTR+ D + DLS + + ++ ER+L A + +L ++ K+
Sbjct: 1402 FAAEADDLKVWLQDKTRIAGDEN--YRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDG 1459
Query: 3028 DDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLT 3207
+ + + + +++ W L + KL++A + R L+ + +
Sbjct: 1460 QALV-QAGNRVPEVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVD 1518
Query: 3208 ATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMF 3387
+ S + L + L+N+ + EI + + ++ + GD D +
Sbjct: 1519 ELDSALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAELVSTGD----DMAHGGHFN 1574
Query: 3388 LRQRLAG---LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDD 3558
+ AG LQ+ +++L+ R+ L + LN F+ + +++ ++
Sbjct: 1575 AQNIEAGTKELQQRFKDLRDPTQRRRAKLEESLNYHKFVFELDSEFQWINEHLPAAKSNE 1634
Query: 3559 IPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDER 3738
+ Q+L QA++ K+H+ + + I + G L H +++ + +++
Sbjct: 1635 LGQNLHQAQSLHKKHKKLEAEIKGHQPMINKALVAGQSLISQQHPEREQVESLCQQLEQA 1694
Query: 3739 RGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITSKFVR 3915
E +KL +L QQ+L D E+ W+ E + E RD + +
Sbjct: 1695 WQDLERHCGERSRKLDMSLKAQQYLFDAGEIESWLGERNNVLRSTEYGRDRDSAAKLLTK 1754
Query: 3916 HQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQK 4095
H+ + EL + ++ H+ + + + + + L K ++ +
Sbjct: 1755 HKTIELELDTYSGIVTEMGHSCAAMVAANHPDSKVLAAKQQLIEKMLKSLHKLASQRQGR 1814
Query: 4096 LFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQH 4275
L ++ + Y ++++W + E + ED D + + K ++ + A
Sbjct: 1815 LMESLYKHEYFLESDEVEQWIREQEQAASSEDYGQDFEHLQLLQNKFDDLKHRVEVGADR 1874
Query: 4276 IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDV 4455
+D ++ + ++ + L L+ R + L +F RDV
Sbjct: 1875 VDQCELLAKKLIDSESPYANEVEKRQEQLRTSWENLLQLLNQREQKLHAAGEIHRFHRDV 1934
Query: 4456 DDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDE 4635
+ I ++ A +Q LG L L + + N++ E + + + L +
Sbjct: 1935 AEALFRIQDKNA-ALSQELGRDLNSALALLRKHEGFENDLVALEAQLQVLVEDSVRLQAK 1993
Query: 4636 GHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
+N A ++ ++ +AW +LKE R L S FL D + +W S +
Sbjct: 1994 YPSNASAIAQQQDKVVAAWNDLKERSTARGDRLAASSDLQTFLTDVRDIVSWSSNLRAAL 2053
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
+E D +H+ + +I+ D R L + V+ ++ + A
Sbjct: 2054 QAEEHVSDAAGATALKIQHDAIYGEIEAREDKFRYLNELSDSMVQTGHYAAADVEEKCAA 2113
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
+ L + R+ + + ++ S + GQ E VQ
Sbjct: 2114 MLDERQKLHAAWNKKKIMLEQKIDLFCFLRDAKQIDNLSSSQQAALSSSDFGQTVEDVQN 2173
Query: 5176 LQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMD 5355
+ +F R + E+V+ + LI H D+ I + + + +L
Sbjct: 2174 KIRKHDEFERLIQT-QEEKVSLLQEHGRKLIEQRHYDSANIQTILQGVLARRQKVKDLCA 2232
Query: 5356 TRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR-----KHQNYL 5520
R LE + L KF DC + I EK + D + + KHQ +
Sbjct: 2233 VRRYKLEDALLYAKFVRDCAEAKYWINEKQKKLEADAASYAEVTNLDEKIKKLQKHQAFQ 2292
Query: 5521 KDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDT 5700
++AA ++ +I+ D + + + +I V++AW+ L + R L +
Sbjct: 2293 AEVAANQGRIQEIQ-DTGVILLSKQHESSPEIKRAIEIVLEAWQGLLAELEQRGRGLEEA 2351
Query: 5701 SDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNAC 5880
D +F + + + W+ + + + + + +D+ LM + +++ ++
Sbjct: 2352 QDSLEFNSQLDKIEAWIRDKEMMVQASDTGRDLEHCNALMRKLDDVDSDMRVDDQRVKHI 2411
Query: 5881 ISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRR-WEDRWEYLQLIL-----------E 6024
L L+N+ + T+ + R+ + W LQ L E
Sbjct: 2412 NQLADKLINQAQ----------VPADTQSVDKRRKDFNYNWRQLQGALNAYRALLGGANE 2461
Query: 6025 VYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
++ F RD + + + S + GR+L LI++ EA E+ A +++ E
Sbjct: 2462 IHVFNRDVDDTADRIAEKSLAMSSTDTGRDLAAVEALIRREEALERDMSAVKQKIDQHET 2521
Query: 6205 LTTFELKETQHREEETAKRR 6264
F +K+ R + +R+
Sbjct: 2522 AAEFLIKKYPERGAQHIERK 2541
Score = 39.7 bits (91), Expect = 1.0
Identities = 48/213 (22%), Positives = 92/213 (42%), Gaps = 21/213 (9%)
Frame = +1
Query: 5686 RLMDTS-DLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSL----- 5838
+LMD ++ + +LL W+ + E+ ++ P + G++ L ++++
Sbjct: 270 QLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPK 329
Query: 5839 ---KAEIDAREENFNACISLGRDLLNRKHYAS------SEIEK--KLIKLTTERAEMMRR 5985
++EI+A N + LN+ Y ++IEK ++++ E+ R
Sbjct: 330 YKERSEIEALYFTINTLLKA----LNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALR 385
Query: 5986 WED-RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
E R E L+ + Y+F + + + E +L L Y R ++ T+K KHEA
Sbjct: 386 DELLRQEKLEQLN--YKFEKKSVLREGYLKEMIQVLSDPRYLRQVDATLK---KHEAISA 440
Query: 6163 SAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
A+ ERF L + +E H +E +R
Sbjct: 441 DILARVERFNDLTAMAEELDRENYHGKERVRRR 473
>gi|50748191|ref|XP_421149.1| PREDICTED: similar to Spectrin beta
chain, brain 4 (Spectrin, non-erythroid beta chain 4)
(Beta-V spectrin) (BSPECV) [Gallus gallus]
Length = 3996
Score = 980 bits (2534), Expect = 0.0
Identities = 609/2082 (29%), Positives = 1042/2082 (49%), Gaps = 76/2082 (3%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVR--VSCKVQDLYMDMRDGKMLLRLLAVLSG 249
+E+ IK L ++R +QKKTFT W+N+ R V +++++Y D++DG L++LL +LSG
Sbjct: 76 YEKDHIKRLQEQRMFMQKKTFTNWMNNIFFRNNVGAEIENIYTDLKDGIYLMQLLELLSG 135
Query: 250 ERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRF 429
E LP+P GKMR+H LEN K + FL+++ V ++ +G +IVDG+ L LGLIW IILRF
Sbjct: 136 ESLPRPNRGKMRVHFLENNSKAITFLKSK-VQVKVIGPENIVDGDRTLILGLIWIIILRF 194
Query: 430 QIQDITFEDAD---NHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHK 600
QI I + + + A EALLLWCQ KTA YPNVNVK+FS SW DGLAFNALIH
Sbjct: 195 QISSIKLDKEEFGGRADQLFANEALLLWCQHKTASYPNVNVKDFSKSWSDGLAFNALIHA 254
Query: 601 HR---------------------------PDLVDYDNLQKSNALYNLQSAFDTAENQLGL 699
H PDL++Y +L++ + NL +AF+ AE +LG+
Sbjct: 255 HSQDTLKFSQLGVTSLFRIATLVGTGFQWPDLINYSSLRQDQPIKNLNNAFNVAEKELGI 314
Query: 700 AKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRY 879
+K LDAEDV V PDE+SI+TYV YYHYF+++KQ KR+ K++ L E D + Y
Sbjct: 315 SKLLDAEDVAVPSPDERSIMTYVSLYYHYFSRMKQGQTNQKRLAKIVFLLKEIDDLKLLY 374
Query: 880 ETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLF 1059
E + SDLL+WI K+ L++R F N+L+ + + F +RT EKPPK+ +KG +E LF
Sbjct: 375 EQMVSDLLKWIKQKVVELDDRVFPNSLQEMWLLMANFKTFRTVEKPPKYQDKGMIEAHLF 434
Query: 1060 TLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARF 1239
+++ RANN R +VP EG+ + D+ + W LEKAEH R L++E++R EKLEQLA RF
Sbjct: 435 NIRTKQRANNLRLYVPPEGRTLQDVEKHWIILEKAEHNRGKALQKEMLRLEKLEQLAKRF 494
Query: 1240 NRKAEMRETWLTENQRLVS-QDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXX 1416
+KA +RET+L + ++++ QD + + +EAA+KK EAI D+ ER
Sbjct: 495 LKKAALRETYLEDMRKVIGKQDFWPESVDRMEAASKKLEAIVADVLPRRERFASLAEMAT 554
Query: 1417 XXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXX 1596
NYH + +I +++ ++ R+ L I +
Sbjct: 555 VISQNNYHSKDQIVKKENSISKQWQDLLDQLQKRQHSLSTMQEILALLRDIDAIMEELKE 614
Query: 1597 IKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYK 1776
+++ + S+D G L++V DLLQKH L++ I+ +++ + + S
Sbjct: 615 LQALVNSQDCGKQLLEVVDLLQKHNLIDLQISSYDDKLTHITQRTAEI--------SKDS 666
Query: 1777 PVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLS 1956
V+ + + +L++ Y+ L+ + RK +LE+ +L +F+ D E E I E+ ++
Sbjct: 667 TVKAEVLYAKVPMLRQLYQNLIAQSRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIAR 726
Query: 1957 STDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEI 2136
+T G+D+ ++ + KHK E + G +L ++ +NI + ++
Sbjct: 727 TTTLGKDVSQITASIQKHKALEAECNSHRAICADVMRRGWDLSQKNPTHEENIQKQRDKL 786
Query: 2137 RDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLL 2316
+ +L++ A+RK RL Q+F D D+ + +L + +++S+D GKDE + + L
Sbjct: 787 QTLWQQLQDEVANRKNRLQAAALIKQYFADIDEANSWLQERQTLVASKDYGKDESSAEAL 846
Query: 2317 LKKHDDVHDELQNFDQHIKVLHAKAESLPQEA------REHPD----------------- 2427
L +H + E+ + ++ L +A ++A E PD
Sbjct: 847 LHRHLRLEKEIAAYSTEMRRLKEQAAIAAEQAPAAMVKTEAPDDLNQKTAKLPFSRTWAT 906
Query: 2428 -------------------IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADS 2550
I + D L+++++ RK+ L + + Y+ S ++
Sbjct: 907 SESALPGSSSLDIHFVPENIWKTQDEIDSLYENLQSMAEDRKKALEEMIEYYRFCSSCEA 966
Query: 2551 VESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEH 2730
+SW+ EK + TL P D VE+M+ ++ + ++ + ++ + LA +
Sbjct: 967 FQSWMREKENIFRTLQPQAD--NVEVMQQKYQSFLTELAAGKGQLGEIESLATKFGKNSP 1024
Query: 2731 PNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLED 2910
+I +++ARW + + ++K +EL + TF DCQ ++DK L +
Sbjct: 1025 GKYTEIQIWLKEIHARWQHMESLKEEKGSELIGVADVRTFLEDCQSIGVLLQDKMGQLRN 1084
Query: 2911 SDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRI 3090
+ N +G+ +R+LS++ER++ I+ K++ L A I+ P E++AI ++ +
Sbjct: 1085 LEP-GNSPAGLESDKRKLSVVEREILVIERKIEYLRSVAKSIKDTNPAESKAITVQVENM 1143
Query: 3091 HQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQL 3270
+ L + + L +A + Q FL+D W + ++ SEE +A AE L
Sbjct: 1144 ESLLVNLKLETQRKRDLLQQAQNQQSFLQDSRRLLLWAEGIREKLRSEEMGVDVASAEHL 1203
Query: 3271 LNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQ-TDPQYMFLRQRLAGLQEGWEELQRMWD 3447
L +H + +EI E + ++ +G ++ Q Q ++ + + + L E +EL+ MW+
Sbjct: 1204 LREHQDLLKEIRSQKERFLQLEELGRKIIQKQPSNSRTRDVHLSVERLAEENKELENMWE 1263
Query: 3448 NRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMD 3627
R L GL LQ F R+ + LS E +L DD+ ++ + K+HQ+F +
Sbjct: 1264 QRWKKLQDGLELQKFNREGDRINAALSSHEAFLRGDDLGDHVDAVRSLQKQHQEFEQLLM 1323
Query: 3628 ANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQ 3807
+I A G L + GH+A+ I ++ + +R E + ++L D+L LQ+
Sbjct: 1324 VLKRRIEAFNENGADLIESGHFASHAIKERMATLRQRWERLVENNSKRKQRLLDSLQLQE 1383
Query: 3808 FLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAIN 3987
F D EL W+EEK A DE+YRD + K H+A + E+ AN++ L
Sbjct: 1384 FNRDAAELLIWMEEKYKIASDESYRDPTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQ 1443
Query: 3988 LGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQL 4167
L D +I ++ EL +W EL E+G KL A +Q+ ++ + D K+ ++
Sbjct: 1444 LIQDDHYAAASIQKKMSELEKKWKELYGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKI 1503
Query: 4168 ENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKA 4347
E + + DL + +++ +E E + A+ ++ H D + I
Sbjct: 1504 EKVLQEAETGHDLRSSRDLLKQHRQLENETHELAEKMNSIVSHAMKMATNHFDS-QRILD 1562
Query: 4348 HRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLP 4527
++ + LQAPLD+RRK LE ++F D E WI+ERL +A + N G+SL
Sbjct: 1563 ETQKYLKRFESLQAPLDERRKLLEAAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLD 1622
Query: 4528 DCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKE 4707
L + + E++ H+ + ++ + G+ +I H + +K QEL +AWQ L++
Sbjct: 1623 VAQSLLQKHKEFQAEVNAHKQQVQRVLDKGRTMIVNQHPSAQKINEKCQELVTAWQGLEK 1682
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
A ++R L S +FL + + EAW++E+ +M + GKDE T ++KH+ L+
Sbjct: 1683 ACEERTKQLQHSVGFQEFLMNTSDLEAWIAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEH 1742
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXX 5067
+I + D I+ L S ++ + Q+ LQ+
Sbjct: 1743 EIAVYQDLIKELNESVQNLPAMGSIQYVEVDAPREQVHSRLRELQELAATRGKKLDETLV 1802
Query: 5068 XYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAN 5247
+ RE +DL W+A ++ A S++ G +YEHV L+ ++ F E G +RV
Sbjct: 1803 LHEFLREYEDLQDWMAQQKQAASSEDYGNNYEHVLQLRAKYDTFRHQLEATG-KRVMTCQ 1861
Query: 5248 DGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLS 5427
+ L+ GH+++ I + L +WE LLE+ R + L+ + ++HK Y D D L+
Sbjct: 1862 QLAENLLNAGHSESREIRQKQKDLRNSWEELLEITRLRGERLKDAEVIHKCYQDLTDALA 1921
Query: 5428 RIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKA 5607
I EK+ ++PDD+ +D V R H ++ +Q+ + A + + ++A
Sbjct: 1922 HIEEKSKSIPDDVAKDMRGVQTQLRNHVALEHELLGNEQQLQDLIHSADHVLTRCSNEQA 1981
Query: 5608 LDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQER 5787
+ +++ +V W+ L+ R L L++F V D W E+ REM ++E
Sbjct: 1982 SGLKAKQQAIVTNWKALKSKVQLRKELLEQAHKLYQFQAQVWDYFSWTSEMIREMRAKET 2041
Query: 5788 PKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTER 5967
+D+S L + HQ L AEI+A+EE +N + LG+ LL + S EI +KL L E+
Sbjct: 2042 IRDISTSSLRLTQHQQLLAEIEAQEEKYNQIVQLGQSLLQDEEIRSKEIRQKLQALLEEK 2101
Query: 5968 AEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLI 6093
++ W+ + ++L I + F +D + L +QE L+
Sbjct: 2102 DKVYSEWQQKKKWLDRIHQEQMFYKDWNHLDKLLNSQEEMLV 2143
Score = 515 bits (1327), Expect = e-144
Identities = 370/1455 (25%), Positives = 672/1455 (45%), Gaps = 60/1455 (4%)
Frame = +1
Query: 1951 LSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLA 2130
L S+D G + V L+ KH+ E L ++ + L +L+ + I +L
Sbjct: 2549 LKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLD 2608
Query: 2131 EIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQ 2310
I ++K LS SR+E+L + F+ + + + ++ + ++ + + +D +Q
Sbjct: 2609 TILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSI-QDPSNLQ 2667
Query: 2311 ---LLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
LL+KH E+ ++ I ++ K E+L HP +IR+++ ++ +L
Sbjct: 2668 DKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMG--HPKSGEIRRQVRMLQERWEKL 2725
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIE------------ 2616
+ R + L D+ + D VE+WI EK ++ G D E
Sbjct: 2726 KRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEF 2785
Query: 2617 ----------EVEIMKH-----------------------RFDTLEQDMKNQEAKVTNVN 2697
E E+ + D LE + +A + +N
Sbjct: 2786 RGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTV--DDAHIKAIN 2843
Query: 2698 DLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVT 2877
LA +L + I R+ +LN +W ++ R +LE A + + +
Sbjct: 2844 ALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITE 2903
Query: 2878 WIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQE 3057
I +K+ +++ D D+ V L RR MER++ I++K++ L E+ + P
Sbjct: 2904 RITEKSVLIQALD-YGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSI 2962
Query: 3058 AQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEE 3237
+ + + W L + ++ + KL + LQ+F ++ W+ + + +
Sbjct: 2963 NDKLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGG 3022
Query: 3238 EPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD--QTDPQYMFLRQRLAGL 3411
P+SL EAE ++ +H +EEI+ E + + G ++ P+ + Q L+ L
Sbjct: 3023 LPKSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPE---IHQSLSRL 3079
Query: 3412 QEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQ 3591
Q+ W EL + W + L Q +LQ F +Q E LS +E +LA +D+ S+ E+
Sbjct: 3080 QKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESL 3139
Query: 3592 LKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEV 3771
++H F +++A EKI + F QL Q+ HY +D I + + + R+ E A
Sbjct: 3140 QRKHMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAAR 3199
Query: 3772 LKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANK 3951
L+++ LQ+ L + E+ WI EK AQD+++RD + +K +HQ+FQ+E+ ANK
Sbjct: 3200 RHLLEESRLLQKLLKNSYEVATWINEKNSIAQDDSWRDPSNLQTKLQKHQSFQAEIMANK 3259
Query: 3952 ERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQ 4131
RLD +K + ++ I +++E+ W+EL + ++K KL DA + + +
Sbjct: 3260 NRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQR 3319
Query: 4132 SIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIK---KAQHIDXXXXXXX 4302
SI D ++W +ENE+ DL +N ++KQ +E ++ + Q +
Sbjct: 3320 SIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQ 3379
Query: 4303 XXXXXHPDELENIKAHRLAVQEQLQR---LQAPLDDRRKALERKKAAFQFGRDVDDEKLW 4473
DELE V + +QR L+ PL +RR +LE + ++F RDVD+E W
Sbjct: 3380 QEKHFLADELEE------RVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAW 3433
Query: 4474 ISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGP 4653
+ E+L +A +++ G+SL LQ+ Q L NEI + + + + GQ+L+ GH+
Sbjct: 3434 VHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASR 3493
Query: 4654 AFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERG 4833
++++EL ++ + LK R+ L +S +AHQFL + + E W++E+ + + G
Sbjct: 3494 KIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYG 3553
Query: 4834 KDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYA 5013
K+E ST+ ++K E + D++ F I + + + +P + I + +I Y
Sbjct: 3554 KNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQRILADYQ 3613
Query: 5014 GLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQ 5193
L Y RE + W++ K+ +A S + GQD + V++L+++F+
Sbjct: 3614 SLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFK 3673
Query: 5194 QFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQIL 5373
F + + +G +V + N+ L GH+ I +NE WE L + TR + L
Sbjct: 3674 DFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTENL 3733
Query: 5374 EASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKHQNYLKDIAAIGEQV 5550
A++ +H++ HD + + EK + DD G D V L + + +D+ AI +++
Sbjct: 3734 RAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKEL 3793
Query: 5551 AQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMV 5730
+I +A L Y K +I R ++V + WR+L R +RL + + N
Sbjct: 3794 ERIRGEAWHLSRTYPQLKE-NIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFNDC 3852
Query: 5731 RDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR 5910
R+L+ W +E+ + S+E DV G ELL+ H K EI+ + + G DL
Sbjct: 3853 RELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDLTRN 3912
Query: 5911 KHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYL 6090
H+ S EIE+KL++L+ ++ W R E + E+ R+ AE+WL A+E +L
Sbjct: 3913 GHFMSVEIEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAAKESFL 3972
Query: 6091 ISKEYGRNLEETIKL 6135
YG + + T L
Sbjct: 3973 SDPSYGVSKDSTTVL 3987
Score = 321 bits (823), Expect = 1e-85
Identities = 265/1364 (19%), Positives = 587/1364 (42%), Gaps = 51/1364 (3%)
Frame = +1
Query: 2269 MSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHPDIRQRLD 2445
+ S D+G V+ L++KH+ L + D+ I L +A L ++ + I+ +LD
Sbjct: 2549 LKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLD 2608
Query: 2446 TTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLA--TLVPGRDIEE 2619
T L++K +++NLS+ R+++L AL L Y + E WI E+ + L ++ ++++
Sbjct: 2609 TILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQD 2668
Query: 2620 VEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDM 2799
+ + E ++ E +T+VN L+++ HP S +I + L RW +L+
Sbjct: 2669 KMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKRA 2728
Query: 2800 VDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSM--- 2970
V + LE + F + WI +K ++ D + ND ++L R+L+
Sbjct: 2729 VAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGD-VGNDYEHCLQLIRKLNEFRG 2787
Query: 2971 -----------------------------------MERDLGAIQAKLDSLHKEADD---- 3033
+ ++ ++ +D H +A +
Sbjct: 2788 ATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALAM 2847
Query: 3034 -IERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTA 3210
+ER+ +E + I + K++++ W+ + + + KL+ A ++ +R++D +T
Sbjct: 2848 KLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERITE 2907
Query: 3211 TQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRV-TQDQTDPQYMF 3387
+ + + + + E L+ +H + EI+ + + R+ T++ + +
Sbjct: 2908 KSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKLT 2967
Query: 3388 LRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQ 3567
++Q+ ++ W LQ R+ L+ LQ F + K+ + + +P+
Sbjct: 2968 MKQQ--EMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPK 3025
Query: 3568 SLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGA 3747
SL +AE+ ++ HQ ++A E+ ++ +G QL GHYA +IH+ + +
Sbjct: 3026 SLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTE 3085
Query: 3748 NREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDA-KTITSKFVRHQA 3924
+ QE KL A LQ+F ++ W+ K +E D+ ++ S +H
Sbjct: 3086 LIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQ 3145
Query: 3925 FQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFD 4104
F+ L A E++D++ A L +K I + + + + ++L + + L +
Sbjct: 3146 FEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLLEE 3205
Query: 4105 ANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDX 4284
+ Q +++ ++ W + +N + ++D D + + +QK + E++ +D
Sbjct: 3206 SRLLQKLLKNSYEVATWINE-KNSIAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDS 3264
Query: 4285 XXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDE 4464
E I++ ++E + L A D+R L+ A F R ++D
Sbjct: 3265 IKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDT 3324
Query: 4465 KLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHA 4644
+ W+ + KA + L + K + L +I +H + ++ N QE E H
Sbjct: 3325 EKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHF 3384
Query: 4645 NGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQD 4824
E+++ +L ++ L++ +++R+G L S ++F D E AW+ E+
Sbjct: 3385 LADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSR 3444
Query: 4825 ERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEK 5004
+ G+ + ++ +KH+ L+++I +A+ + K V + +I + ++E
Sbjct: 3445 DYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASRKIMEQMKELET 3504
Query: 5005 LYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQE 5184
L+ + E+ D+ W+A++ + + + G++ E Q L
Sbjct: 3505 SVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGKNEESTQALLR 3564
Query: 5185 RFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRA 5364
+ + D E R+ + +LI + ++P I + +++LL+ +T+
Sbjct: 3565 KLEATKLDMEGF-RPRIEKVQETGASLINKDNPESPAILSKLQRILADYQSLLQKAETQR 3623
Query: 5365 QILEASRLLHKFYHDCRDCLSRIMEKTH-AMPDDLGRDSSSVGALSRKHQNYLKDIAAIG 5541
+ L+ L++F + + + + K A DD G+D V L +K ++++ +I +G
Sbjct: 3624 KRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKPLG 3683
Query: 5542 E-QVAQIERDAAEL-RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFK 5715
+V + A++L +DG++ K I R ++ + W L RT L + +
Sbjct: 3684 HSKVLSLNELASKLEKDGHS--KTDIIQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQ 3741
Query: 5716 FMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGR 5895
+ + V ++ WM E + ++ + D+ GV+ L++ + ++ ++ A +
Sbjct: 3742 YDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAW 3801
Query: 5896 DLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFA 6075
L I ++L + + +++ +R L +V + D +W
Sbjct: 3802 HLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFNDCRELMAWANE 3861
Query: 6076 QEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 6207
+IS+E ++ LIK+H+ +++ E+++L E++
Sbjct: 3862 MHALVISEELANDVLGAELLIKRHDEYKREI---EKQWLKYEEI 3902
Score = 285 bits (729), Expect = 1e-74
Identities = 279/1539 (18%), Positives = 626/1539 (40%), Gaps = 50/1539 (3%)
Frame = +1
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
I ++ + + K++++LLD +R+ L + + D+ + +KE + +++S D G+
Sbjct: 567 IVKKENSISKQWQDLLDQLQKRQHSLSTMQEILALLRDIDAIMEELKELQALVNSQDCGK 626
Query: 1975 DIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINK 2154
++ V LL KH + + + L + E+ +S ++ + ++ +R
Sbjct: 627 QLLEVVDLLQKHNLIDLQISSYDDKLTHITQRTAEISKDSTVKAEVLYAKVPMLRQLYQN 686
Query: 2155 LKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDD 2334
L S +RK +L ++ ++FF D + + ++ + ++ + +GKD + ++KH
Sbjct: 687 LIAQSRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIARTTTLGKDVSQITASIQKHKA 746
Query: 2335 VHDELQNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLID 2511
+ E + + + L Q+ H + I+++ D +L++ RK RL
Sbjct: 747 LEAECNSHRAICADVMRRGWDLSQKNPTHEENIQKQRDKLQTLWQQLQDEVANRKNRLQA 806
Query: 2512 ALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTN 2691
A + + ++D D SW+ E+ L+A+ G+D E + HR LE+++ ++
Sbjct: 807 AALIKQYFADIDEANSWLQERQTLVASKDYGKDESSAEALLHRHLRLEKEIAAYSTEMRR 866
Query: 2692 VNDLAR--------QLLNVEHPNS---------------------------------DDI 2748
+ + A ++ E P+ ++I
Sbjct: 867 LKEQAAIAAEQAPAAMVKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSLDIHFVPENI 926
Query: 2749 LHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTN 2928
Q+++++ + L+ M + ++ LE F C+ +W+ +K + L
Sbjct: 927 WKTQDEIDSLYENLQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENIFR---TLQP 983
Query: 2929 DLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDI 3108
V +Q++ +L A + +L + A + P + I+ +K IH W
Sbjct: 984 QADNVEVMQQKYQSFLTELAAGKGQLGEIESLATKFGKNSPGKYTEIQIWLKEIHARWQH 1043
Query: 3109 LNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAA 3288
+ E ++L D++ FL D L Q+ + E S A E + +
Sbjct: 1044 MESLKEEKGSELIGVADVRTFLEDCQSIGVLLQDKMGQLRNLEPGNSPAGLESDKRKLSV 1103
Query: 3289 IREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLS 3468
+ EI + +R++ + +D + + ++ ++ L+ ++ LL
Sbjct: 1104 VEREILVIERKIEYLRSVAKSI-KDTNPAESKAITVQVENMESLLVNLKLETQRKRDLLQ 1162
Query: 3469 QGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIR 3648
Q N Q FL+D+++ + L +++ + AE+ L+ HQD + + + E+
Sbjct: 1163 QAQNQQSFLQDSRRLLLWAEGIREKLRSEEMGVDVASAEHLLREHQDLLKEIRSQKERFL 1222
Query: 3649 AVGMFGDQLCQD--GHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDC 3822
+ G ++ Q + +H + E ++ KKL+D L LQ+F +
Sbjct: 1223 QLEELGRKIIQKQPSNSRTRDVHLSVERLAEENKELENMWEQRWKKLQDGLELQKFNREG 1282
Query: 3823 DELREWIE--EKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
D + + E +R D+ + S +HQ F+ L K R++ +L +
Sbjct: 1283 DRINAALSSHEAFLRG-DDLGDHVDAVRSLQKQHQEFEQLLMVLKRRIEAFNENGADLIE 1341
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENE 4176
I ++ L +W+ L + ++ Q+L D+ + Q + + A++ W + + +
Sbjct: 1342 SGHFASHAIKERMATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWMEE-KYK 1400
Query: 4177 MTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRL 4356
+ ++ D T V ++ E EM+ +H +I+
Sbjct: 1401 IASDESYRDPTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQLIQDDHYAAASIQKKMS 1460
Query: 4357 AVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
++++ + L + +R L + Q + D K I + + + G L
Sbjct: 1461 ELEKKWKELYGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVLQEAETGHDLRSSR 1520
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVK 4716
L K + L NE +N I ++ ++ H + + Q+ ++ L+ +
Sbjct: 1521 DLLKQHRQLENETHELAEKMNSIVSHAMKMATN-HFDSQRILDETQKYLKRFESLQAPLD 1579
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
+R+ L + ++F + W++E+ GK ++ ++KH+ Q++++
Sbjct: 1580 ERRKLLEAAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKEFQAEVN 1639
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
++ + K + + P ++I + ++ + GL+
Sbjct: 1640 AHKQQVQRVLDKGRTMIVNQHPSAQKINEKCQELVTAWQGLEKACEERTKQLQHSVGFQE 1699
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
DL WIA+K + S++ G+D + L ++ + + + + + N+
Sbjct: 1700 FLMNTSDLEAWIAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEHEIA-VYQDLIKELNESV 1758
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF---YHDCRDCLS 5427
L G + ++ ++ L EL TR + L+ + +LH+F Y D +D ++
Sbjct: 1759 QNLPAMGSIQYVEVDAPREQVHSRLRELQELAATRGKKLDETLVLHEFLREYEDLQDWMA 1818
Query: 5428 RIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKA 5607
+ +K A +D G + V L K+ + + A G++V ++ A L + ++
Sbjct: 1819 Q--QKQAASSEDYGNNYEHVLQLRAKYDTFRHQLEATGKRVMTCQQLAENLLNA-GHSES 1875
Query: 5608 LDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQER 5787
+I ++ ++ +W L + R RL D + K + D L ++E + + +
Sbjct: 1876 REIRQKQKDLRNSWEELLEITRLRGERLKDAEVIHKCYQDLTDALAHIEEKSKSI-PDDV 1934
Query: 5788 PKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR-KHYASSEIEKKLIKLTTE 5964
KD+ GV+ + NH +L+ E+ E+ I +L R + +S ++ K + T
Sbjct: 1935 AKDMRGVQTQLRNHVALEHELLGNEQQLQDLIHSADHVLTRCSNEQASGLKAKQQAIVTN 1994
Query: 5965 RAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKK 6144
+ + + R E L+ ++YQF SW + +KE R++ + + +
Sbjct: 1995 WKALKSKVQLRKELLEQAHKLYQFQAQVWDYFSWTSEMIREMRAKETIRDISTSSLRLTQ 2054
Query: 6145 HEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
H+ AQEE++ + +L L++ + R +E ++
Sbjct: 2055 HQQLLAEIEAQEEKYNQIVQLGQSLLQDEEIRSKEIRQK 2093
Score = 280 bits (716), Expect = 3e-73
Identities = 271/1436 (18%), Positives = 593/1436 (40%), Gaps = 63/1436 (4%)
Frame = +1
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
+ + G+ + VE +KHEA E + + +E+ D +I + +
Sbjct: 2549 LKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLD 2608
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLG--AHLMD 1644
+ +RR +L+ ++ + + +L + ++L D
Sbjct: 2609 TILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQD 2668
Query: 1645 VEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQK 1824
LLQKH + E++I E + + + + + P + G I + +LQ+
Sbjct: 2669 KMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHP--------KSGEIRRQVRMLQE 2720
Query: 1825 RYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLA 2004
R+++L A R + LED++ +F V ++E I+E+E +++ D G D L+
Sbjct: 2721 RWEKLKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIR 2780
Query: 2005 K---HKNAENNL--------------------------RDLEKYLDRLDVSGKELQDESI 2097
K + A + L R+ E +++ +D+ + D I
Sbjct: 2781 KLNEFRGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHME-IDILETTVDDAHI 2839
Query: 2098 PGSDNIPPRL-----AEIRDYINKLKELSA----------SRKERLAGGVEYYQFFTDAD 2232
+ + +L E + + K+L+ + + +L G +E + + D
Sbjct: 2840 KAINALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREID 2899
Query: 2233 DVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEA 2412
D+ + + ++ + D GKD +V+ L+++H+++ E+ I+ L ++ L +
Sbjct: 2900 DITERITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRL---S 2956
Query: 2413 REHPDIRQRLDTTLKQK------AELENLSQLRKQRLIDALSLYKLYSDADSVESWIDE- 2571
+P I +L T+KQ+ L+ ++ RK++L + L K S+ + WI
Sbjct: 2957 TRNPSINDKL--TMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNI 3014
Query: 2572 KGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDIL 2751
+G + A +P + + E E M +++++ + + ++++ +QL N H + +I
Sbjct: 3015 RGLMEAGGLP-KSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIH 3073
Query: 2752 HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTND 2931
++L W +L ++ +L +A L+ F ++T +W+ K L + D L +
Sbjct: 3074 QSLSRLQKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANED-LGDS 3132
Query: 2932 LSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDIL 3111
+S V LQR+ E+ L A K+D + A + + + ++ I + + + + L
Sbjct: 3133 VSSVESLQRKHMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKL 3192
Query: 3112 NKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAI 3291
+ L+E+ LQ+ L++ W+ + +A ++ + + + L +H +
Sbjct: 3193 LENAAARRHLLEESRLLQKLLKNSYEVATWIN-EKNSIAQDDSWRDPSNLQTKLQKHQSF 3251
Query: 3292 REEIDGYAEDYKKMRAMGDRVTQDQ-TDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLS 3468
+ EI +++ G+++ +++ P+ ++ RL ++E WEEL +++ L
Sbjct: 3252 QAEIMANKNRLDSIKSEGEKMIRERHYAPE--AIQSRLQEMEELWEELLASCQDKRAKLQ 3309
Query: 3469 QGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIR 3648
F R + E L EN L L + LK+ ++ + ++ ++++
Sbjct: 3310 DAYKALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQ 3369
Query: 3649 AVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
+ + Q+ H+ AD++ ++ + +R + R+ QE L+ + +F D DE
Sbjct: 3370 ELVNTAQEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDE 3429
Query: 3829 LREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD--- 3996
W+ EK+ A Y + T+ S +HQ ++E+++ D L A ++ G
Sbjct: 3430 ELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSR----DALTKAVLSTGQKLV 3485
Query: 3997 -DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLEN 4173
I Q++EL T + L+ + Q+L + ++ + D++ W +
Sbjct: 3486 RGGHSASRKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSF 3545
Query: 4174 EMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHR 4353
+ D + + ++K + +M I+ E I +
Sbjct: 3546 ILETSDYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKL 3605
Query: 4354 LAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
+ Q L + +RK L+ + +QF R+ W+S + +A++ + G+ L
Sbjct: 3606 QRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGV 3665
Query: 4534 HRLQKNLQLLSNEID--NHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKE 4707
L+K + NEI H + + +L +GH+ +K+ +++ W++L
Sbjct: 3666 EVLEKKFKDFVNEIKPLGHSK-VLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCH 3724
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
A++ R +L +++ HQ+ +D E + WM E+E + D+ G D + + + E ++
Sbjct: 3725 AIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVER 3784
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXX 5067
D+ + + +A L E I R +++ + L
Sbjct: 3785 DLGAIMKELERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQ 3844
Query: 5068 XYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTEN--IGSERVAN 5241
+ +L+ W + + S+E D ++L +R ++ R+ E + E +
Sbjct: 3845 VQLYFNDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQR 3904
Query: 5242 ANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHD 5409
A D L +GH + I E LLEL + ++ E+ + + Y +
Sbjct: 3905 AG---DDLTRNGHFMSVEIE----------EKLLELSELMKKVKESWNVRKELYEE 3947
Score = 276 bits (707), Expect = 4e-72
Identities = 252/1239 (20%), Positives = 515/1239 (41%), Gaps = 52/1239 (4%)
Frame = +1
Query: 2602 GRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARW 2781
G ++EVE + + + E+ + +Q+ K+T++ + A +L + I H+ + + R
Sbjct: 2555 GSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKLDTILQRK 2614
Query: 2782 AQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALT-NDLSGVMKLQR 2958
Q++++ +R +L+ A L F + E WI ++ + LED ++L MKL +
Sbjct: 2615 KQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQDKMKLLQ 2674
Query: 2959 RLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEA 3138
+ + E ++ A + + ++K+ + + ++ IR ++ + + W+ L + V
Sbjct: 2675 KHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWEKLKRAVAARGK 2734
Query: 3139 KLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLN-------------- 3276
L+++ D FL+ +D +AW+ + + + QL+
Sbjct: 2735 MLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFRGATSGLPG 2794
Query: 3277 QHAAIREEI--------------------------------DGYAEDYKKMRAMGDRVTQ 3360
+ + EE D + + + +R +
Sbjct: 2795 EETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALAMKLERQNK 2854
Query: 3361 DQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
++T Y QR L E W + + L L + +R+ ++++
Sbjct: 2855 EETKTIY----QRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERITEKSV 2910
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
+ D + +E EN ++RH++ ++ KI + + +L DK+ K
Sbjct: 2911 LIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKLTMKQ 2970
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
+ + + +A++ +KL + LQ+F S+ E+ +WI+ IR E K++
Sbjct: 2971 QEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQN--IRGLMEAGGLPKSLN 3028
Query: 3901 ---SKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEK 4071
S HQ + E+ A ER + L + L + I + L W EL +
Sbjct: 3029 EAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTELIQ 3088
Query: 4072 TTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIET 4251
+E+ KLF A Q + + + W + E + ED +++V +K E
Sbjct: 3089 AWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQFEK 3148
Query: 4252 EMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
+ + + ID + +NI AV + ++L RR LE +
Sbjct: 3149 SLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLLEESRL 3208
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
+ ++ + WI+E+ +A+ + + +LQK+ Q EI ++ ++ I +
Sbjct: 3209 LQKLLKNSYEVATWINEKNSIAQDDSWRDPSNLQTKLQKH-QSFQAEIMANKNRLDSIKS 3267
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
G+++I E H A + ++QE+ W+EL + +D++ L ++ KA F + E W
Sbjct: 3268 EGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDTEKW 3327
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+ + E + D + +KK E L+ DI D ++ L A +F +EK L +
Sbjct: 3328 LEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHFLAD 3387
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENG 5151
+++ R Q+ + Y L+D Y R++D+ L W+ +K +A S++ G
Sbjct: 3388 ELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSRDYG 3447
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
Q VQ LQE+ Q + + + A + G L+ GH+ + I L +
Sbjct: 3448 QSLATVQSLQEKHQNLENEISSRDALTKAVLSTG-QKLVRGGHSASRKIMEQMKELETSV 3506
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKH 5508
ENL R Q L S H+F + D + + E++ + D G++ S AL RK
Sbjct: 3507 ENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGKNEESTQALLRKL 3566
Query: 5509 QNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSR 5688
+ D+ ++ +++ A L + ++ I S+ ++ ++ L + + R
Sbjct: 3567 EATKLDMEGFRPRIEKVQETGASLINK-DNPESPAILSKLQRILADYQSLLQKAETQRKR 3625
Query: 5689 LMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREEN 5868
L + L++F + + W+ + S + +D+ GVE+L + EI +
Sbjct: 3626 LQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKPLGHS 3685
Query: 5869 FNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM-RRWEDRWEYLQLILEVYQFARD 6045
++ L + ++ ++I +K K E E + + R E L+ +V+Q+ D
Sbjct: 3686 KVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQYDHD 3745
Query: 6046 AAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
+ W+ +E + +YG +L L+ + E E+
Sbjct: 3746 VDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVER 3784
Score = 271 bits (694), Expect = 1e-70
Identities = 197/796 (24%), Positives = 371/796 (45%), Gaps = 4/796 (0%)
Frame = +1
Query: 1174 RELVLKEELIRQEKLEQ--LAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKK 1347
+E +L+ R+ LE+ L + + + TW+ E ++QD+ D S+++ +K
Sbjct: 3189 KEKLLENAAARRHLLEESRLLQKLLKNSYEVATWINEKNS-IAQDDSWRDPSNLQTKLQK 3247
Query: 1348 HEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVR 1527
H++ + +I A + R ++ I R + + +R +
Sbjct: 3248 HQSFQAEIMANKNRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAK 3307
Query: 1528 LELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGER 1707
L+ + +++ L + L+ + L+K LE DI +R
Sbjct: 3308 LQDAYKALHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDR 3367
Query: 1708 VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKR 1887
+ + AQ F+ K ++ER D L +RYK L D ER+ LE ++
Sbjct: 3368 LQELVNTAQEFQQE--------KHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRL 3419
Query: 1888 LCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDV 2067
+F+ DV E + E+ + SS D G+ + TV L KH+N EN + + +
Sbjct: 3420 QYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLS 3479
Query: 2068 SGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRY 2247
+G++L S I ++ E+ + LK + R++RL E +QF T+ DV+ +
Sbjct: 3480 TGQKLVRGGHSASRKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETW 3539
Query: 2248 LYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHI-KVLHAKAESLPQEAREHP 2424
L + ++ + D GK+E + Q LL+K + +++ F I KV A + ++ E P
Sbjct: 3540 LAERSFILETSDYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESP 3599
Query: 2425 DIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPG 2604
I +L L L ++ +++RL + LY+ + V++W+ K + + G
Sbjct: 3600 AILSKLQRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYG 3659
Query: 2605 RDIEEVEIMKHRFDTLEQDMKN-QEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARW 2781
+D++ VE+++ +F ++K +KV ++N+LA +L H +D I R ++N W
Sbjct: 3660 QDLDGVEVLEKKFKDFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMW 3719
Query: 2782 AQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRR 2961
+L + + L A ++ + D E W+++K V+ D D DL GV L +
Sbjct: 3720 EKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVV-DIDDYGYDLPGVQTLLSQ 3778
Query: 2962 LSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAK 3141
L +ERDLGAI +L+ + EA + R PQ + I E + + + W L+KK E +A+
Sbjct: 3779 LEGVERDLGAIMKELERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKAR 3838
Query: 3142 LDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAED 3321
L +A +Q + D AW V SEE + AE L+ +H + EI+
Sbjct: 3839 LSQAEQVQLYFNDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLK 3898
Query: 3322 YKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRD 3501
Y++++ GD +T++ + + ++L L E ++++ W+ R+ L + +Q+ R+
Sbjct: 3899 YEEIQRAGDDLTRN-GHFMSVEIEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRE 3957
Query: 3502 AKQAEVMLSQQENYLA 3549
+QAE L+ +E++L+
Sbjct: 3958 LEQAEAWLAAKESFLS 3973
Score = 262 bits (669), Expect = 1e-67
Identities = 205/1036 (19%), Positives = 456/1036 (43%), Gaps = 5/1036 (0%)
Frame = +1
Query: 811 IQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEF 990
+QG+ K E + + ++ + ++ +WI L+ +L + + E
Sbjct: 2980 LQGQ--AKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKSLNEAESMIEE- 3036
Query: 991 NDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEH 1170
+ R +E + + L + AN+ P + ++ + +AW L +A
Sbjct: 3037 HQQRKEEIEARVERFNSL-----SNYGQQLANSGHYATPEIHQSLSRLQKAWTELIQAWQ 3091
Query: 1171 ERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKH 1350
E+ + +L + + L+ +F E E+WL+ + ++ ++ G+ +SSVE+ +KH
Sbjct: 3092 EQYI----KLFQAQDLQ----KFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKH 3143
Query: 1351 EAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRL 1530
E + A E+ ++D I R + V ARR L
Sbjct: 3144 MQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLL 3203
Query: 1531 ELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERV 1710
E S +QK+ K+ + +D +++ LQKH +++I R+
Sbjct: 3204 EESRLLQKLLKNSYEVATWINE-KNSIAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRL 3262
Query: 1711 NNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRL 1890
++ ++ ++ + P I R +++ ++ELL +++ +L+D +
Sbjct: 3263 DSIKSEGEKMIRE--------RHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKA 3314
Query: 1891 CQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVS 2070
F + + E +++ E L + + D+V ++ L K + E ++ L L +
Sbjct: 3315 LHFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNT 3374
Query: 2071 GKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYL 2250
+E Q E +D + R+ ++ L++ R+ L Y+FF D D+ ++
Sbjct: 3375 AQEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWV 3434
Query: 2251 YDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDI 2430
++ L + SS D G+ TVQ L +KH ++ +E+ + D K + + + L + H
Sbjct: 3435 HEKLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGG--HSAS 3492
Query: 2431 RQRLDTTLKQKAELENL---SQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVP 2601
R+ ++ + + +ENL + +R+QRL+ + ++ ++ VE+W+ E+ +L T
Sbjct: 3493 RKIMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDY 3552
Query: 2602 GRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARW 2781
G++ E + + + + + DM+ ++ V + L+N ++P S IL + ++ A +
Sbjct: 3553 GKNEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQRILADY 3612
Query: 2782 AQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRR 2961
L + +R L+ +L F + Q W+ K + E SD DL GV L+++
Sbjct: 3613 QSLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAE-SDDYGQDLDGVEVLEKK 3671
Query: 2962 LSMMERDLGAI-QAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEA 3138
++ + +K+ SL++ A +E++ + I++ K+I+++W+ L ++
Sbjct: 3672 FKDFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTE 3731
Query: 3139 KLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAE 3318
L A + ++ D+D + W+ + V ++ L + LL+Q + ++ +
Sbjct: 3732 NLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMK 3791
Query: 3319 DYKKMRAMGDRVTQDQTDPQYM-FLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFL 3495
+ +++R G+ +T PQ + +RL + E W L + + R+ LSQ +Q++
Sbjct: 3792 ELERIR--GEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYF 3849
Query: 3496 RDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQL 3675
D ++ ++ + +++ + AE +KRH ++ ++ K + GD L
Sbjct: 3850 NDCRELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDL 3909
Query: 3676 CQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKM 3855
++GH+ + +I +K + E +E + ++ +Q + ++ W+ K
Sbjct: 3910 TRNGHFMSVEIEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAAKE 3969
Query: 3856 IRAQDETYRDAKTITS 3903
D +Y +K T+
Sbjct: 3970 SFLSDPSYGVSKDSTT 3985
Score = 257 bits (657), Expect = 2e-66
Identities = 262/1389 (18%), Positives = 563/1389 (39%), Gaps = 47/1389 (3%)
Frame = +1
Query: 2239 DRYLYDTLRVMSSEDVGKDE-GTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR 2415
+ YL D +V+ +D + ++ KK + + ++ + L A + Q
Sbjct: 502 ETYLEDMRKVIGKQDFWPESVDRMEAASKKLEAIVADVLPRRERFASLAEMATVISQNNY 561
Query: 2416 EHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLAT 2592
D I ++ ++ KQ +L + Q R+ L + L D D++ + E L+ +
Sbjct: 562 HSKDQIVKKENSISKQWQDLLDQLQKRQHSLSTMQEILALLRDIDAIMEELKELQALVNS 621
Query: 2593 LVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLN 2772
G+ + EV + + + ++ + + + K+T++ ++ ++ + + L
Sbjct: 622 QDCGKQLLEVVDLLQKHNLIDLQISSYDDKLTHITQRTAEISKDSTVKAEVLYAKVPMLR 681
Query: 2773 ARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL 2952
+ L ++++LE A +L F DC+E WI +K ++ + L D+S +
Sbjct: 682 QLYQNLIAQSRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIARTT-TLGKDVSQITAS 740
Query: 2953 QRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREH 3132
++ +E + + +A + + D+ ++ P + I++ ++ +W L +V
Sbjct: 741 IQKHKALEAECNSHRAICADVMRRGWDLSQKNPTHEENIQKQRDKLQTLWQQLQDEVANR 800
Query: 3133 EAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGY 3312
+ +L A ++++ D+D +WL Q VAS++ + + AE LL++H + +EI Y
Sbjct: 801 KNRLQAAALIKQYFADIDEANSWLQERQTLVASKDYGKDESSAEALLHRHLRLEKEIAAY 860
Query: 3313 AEDYKKMR------------------------------------AMGDRVTQDQTDPQYM 3384
+ + ++++ A + +
Sbjct: 861 STEMRRLKEQAAIAAEQAPAAMVKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSLDIH 920
Query: 3385 FLRQRLAGLQEG----WEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAK 3552
F+ + + Q+ +E LQ M ++R+ L + + F + + + ++EN
Sbjct: 921 FVPENIWKTQDEIDSLYENLQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENIFRT 980
Query: 3553 DDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNID 3732
+ + E +++Q F+T + A ++ + + ++ +I + I
Sbjct: 981 --LQPQADNVEVMQQKYQSFLTELAAGKGQLGEIESLATKFGKNSPGKYTEIQIWLKEIH 1038
Query: 3733 ERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQD-ETYRDAKTITSKF 3909
R +E +L ++ FL DC + +++KM + ++ E + S
Sbjct: 1039 ARWQHMESLKEEKGSELIGVADVRTFLEDCQSIGVLLQDKMGQLRNLEPGNSPAGLESDK 1098
Query: 3910 VRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKG 4089
+ + E+ + +++ L+ A ++ D P I Q+E + + L+ T+ K
Sbjct: 1099 RKLSVVEREILVIERKIEYLRSVAKSIKDTNPAESKAITVQVENMESLLVNLKLETQRKR 1158
Query: 4090 QKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKA 4269
L A QQ ++Q + WA + ++ E+ D+ + +++ + E+ +
Sbjct: 1159 DLLQQAQNQQSFLQDSRRLLLWAEGIREKLRSEEMGVDVASAEHLLREHQDLLKEIRSQK 1218
Query: 4270 QHIDXXXXXXXXXXXXHPDELENIKAHRLAVQ---EQLQRLQAPLDDRRKALERKKAAFQ 4440
+ P H L+V+ E+ + L+ + R K L+ +
Sbjct: 1219 ERFLQLEELGRKIIQKQPSNSRTRDVH-LSVERLAEENKELENMWEQRWKKLQDGLELQK 1277
Query: 4441 FGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQ 4620
F R+ D +S + +LG+ + LQK Q + + I NG
Sbjct: 1278 FNREGDRINAALSSHEAFLRGDDLGDHVDAVRSLQKQHQEFEQLLMVLKRRIEAFNENGA 1337
Query: 4621 ELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSE 4800
+LI+ GH A ++++ LR W+ L E RK L +S + +F D E WM E
Sbjct: 1338 DLIESGHFASHAIKERMATLRQRWERLVENNSKRKQRLLDSLQLQEFNRDAAELLIWM-E 1396
Query: 4801 QELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQ 4980
++ + DE +D + ++K HE + ++ L K ++ +++ IQ
Sbjct: 1397 EKYKIASDESYRDPTNVLRKLKWHEAAEKEMMANEKHFITLIKKGNQLIQDDHYAAASIQ 1456
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
+ +++EK + L L + D + I E V E G D
Sbjct: 1457 KKMSELEKKWKELYGKMIERGDKLRQAGQQEQLMELLQDAKKKIEKIEKVLQEAETGHDL 1516
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
+ L ++ +Q +T + + + + + H D+ I + +E+L
Sbjct: 1517 RSSRDLLKQHRQLENETHELAEKMNSIVSHAMK--MATNHFDSQRILDETQKYLKRFESL 1574
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTH-AMPDDLGRDSSSVGALSRKHQNY 5517
+D R ++LEA+ L++FYH L+ I E+ A + G+ +L +KH+ +
Sbjct: 1575 QAPLDERRKLLEAAVDLYEFYHYHDMELNWINERLPIASSTNCGKSLDVAQSLLQKHKEF 1634
Query: 5518 LKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMD 5697
++ A +QV ++ D A I + E+V AW+ L C+ RT +L
Sbjct: 1635 QAEVNAHKQQVQRV-LDKGRTMIVNQHPSAQKINEKCQELVTAWQGLEKACEERTKQLQH 1693
Query: 5698 TSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNA 5877
+ +F+ DL W+ E + + S++ KD G L+ H+ L+ EI ++
Sbjct: 1694 SVGFQEFLMNTSDLEAWIAEKRPLVMSKDYGKDEDGTLKLLQKHKVLEHEIAVYQDLIKE 1753
Query: 5878 CISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVA 6057
++L E++ ++ + E+ R + L L +++F R+
Sbjct: 1754 LNESVQNLPAMGSIQYVEVDAPREQVHSRLRELQELAATRGKKLDETLVLHEFLREYEDL 1813
Query: 6058 ESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQH 6237
+ W+ Q+ S++YG N E ++L K++ F A +R + ++L L H
Sbjct: 1814 QDWMAQQKQAASSEDYGNNYEHVLQLRAKYDTFRHQLEATGKRVMTCQQLAE-NLLNAGH 1872
Query: 6238 REEETAKRR 6264
E +++
Sbjct: 1873 SESREIRQK 1881
Score = 236 bits (603), Expect = 4e-60
Identities = 227/1178 (19%), Positives = 497/1178 (41%), Gaps = 57/1178 (4%)
Frame = +1
Query: 2902 LEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDI 3081
L+ SD L + + V +L R+ E+ L + K+ SL ++A+ +E++ + I+ +
Sbjct: 2549 LKSSD-LGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKL 2607
Query: 3082 KRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA--SEEEPQSLA 3255
I Q + R KL A L F ++L + W++ +++ S ++P +L
Sbjct: 2608 DTILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQ 2667
Query: 3256 EAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQ 3435
+ +LL +H EI E + G+ + P+ +R+++ LQE WE+L+
Sbjct: 2668 DKMKLLQKHQVFEAEILANEEIITDVNKKGEALVS-MGHPKSGEIRRQVRMLQERWEKLK 2726
Query: 3436 RMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDF- 3612
R R +L + FL+ Q E + ++E + D+ E +++ +F
Sbjct: 2727 RAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNEFR 2786
Query: 3613 ------------------------------------------ITTMDANDEKIRAVGMFG 3666
I +D I+A+
Sbjct: 2787 GATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINALA 2846
Query: 3667 DQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIE 3846
+L + I+++ + ++E+ + +KL+ AL + + + D++ E I
Sbjct: 2847 MKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITERIT 2906
Query: 3847 EKMIRAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTI 4023
EK + Q Y +D +++ + RH+ + E+ K +++ L+ + L P + +
Sbjct: 2907 EKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSINDKL 2966
Query: 4024 DPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGD 4203
+ +E+ W L+ +++ +KL + + Q + + ++ +W + M P
Sbjct: 2967 TMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKS 3026
Query: 4204 LTTVNVAMQKQHLIETEMIKKAQHIDXXXXX----XXXXXXXHPDELENIKAHRLAVQEQ 4371
L +++ + E+ + + + P+ +++ + A E
Sbjct: 3027 LNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTEL 3086
Query: 4372 LQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKN 4551
+Q Q +A + +K F V+ + W+S + ++LG+S+ LQ+
Sbjct: 3087 IQAWQEQYIKLFQAQDLQK----FYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRK 3142
Query: 4552 LQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGD 4731
++ I+++ + Q+LI H + + Q + ++L E R+
Sbjct: 3143 HMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHL 3202
Query: 4732 LGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADT 4911
L ES + L + E W++E+ + QD+ +D + + +++KH+ Q++I +
Sbjct: 3203 LEESRLLQKLLKNSYEVATWINEKNS-IAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNR 3261
Query: 4912 IRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREI 5091
+ ++ ++ K + E+ E IQ R ++E+L+ L R I
Sbjct: 3262 LDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSI 3321
Query: 5092 DDLLQWIADKEVVAGSQENGQDY----EHVQMLQERFQQFARDTENIGSERVANANDGCD 5259
+D +W+ D E + + D H++ +E Q A + + E V A +
Sbjct: 3322 EDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRL-QELVNTAQE--- 3377
Query: 5260 TLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME 5439
H A + D L + +++L + + R LEASRL ++F+ D + L+ + E
Sbjct: 3378 -FQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHE 3436
Query: 5440 KTH-AMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL-RDGYAGDKALD 5613
K A D G+ ++V +L KHQN +I++ + +L R G++ + +
Sbjct: 3437 KLPMASSRDYGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASRKIM 3496
Query: 5614 IGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPK 5793
+E E + +L+ R RLM + + +F+ + D+ W+ E + + + K
Sbjct: 3497 EQMKELET--SVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGK 3554
Query: 5794 DVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAE 5973
+ + L+ ++ K +++ G L+N+ + S I KL ++ +
Sbjct: 3555 NEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLINKDNPESPAILSKLQRILADYQS 3614
Query: 5974 MMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEA 6153
++++ E + + LQ ++YQF R+ + ++WL +++ S +YG++L+ L KK +
Sbjct: 3615 LLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFKD 3674
Query: 6154 F-EKSAFAQEERFLALEKLTTFELKETQHREEETAKRR 6264
F + + L+L +L + +L++ H + + ++R
Sbjct: 3675 FVNEIKPLGHSKVLSLNELAS-KLEKDGHSKTDIIQKR 3711
Score = 233 bits (595), Expect = 4e-59
Identities = 192/930 (20%), Positives = 391/930 (41%), Gaps = 50/930 (5%)
Frame = +1
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
YL D+ S+++ E +++H+ F + + DEKI ++ ++L +DG +I K
Sbjct: 2548 YLKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQHKL 2607
Query: 3721 RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTIT 3900
I +R+ + ++ +KL+ AL L F + E +WI E+M + +D + +D +
Sbjct: 2608 DTILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQDPSNLQ 2667
Query: 3901 SK---FVRHQAFQSELAANKERLDQLK---HAAINLGDDKPEYHGTIDPQIEELATQWDE 4062
K +HQ F++E+ AN+E + + A +++G K G I Q+ L +W++
Sbjct: 2668 DKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPK---SGEIRRQVRMLQERWEK 2724
Query: 4063 LEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLE----------------------NE 4176
L++ +G+ L D+ ++Q + ++ W + E NE
Sbjct: 2725 LKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLNE 2784
Query: 4177 M--TREDQPGDLTTVN---------------VAMQKQHL-IETEMIKKA---QHIDXXXX 4293
PG+ T V+ VA++ + +E ++++ HI
Sbjct: 2785 FRGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAINA 2844
Query: 4294 XXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLW 4473
+ +E + I R + E+ L+ R+ LE R++DD
Sbjct: 2845 LAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITER 2904
Query: 4474 ISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGP 4653
I+E+ VL +A + G+ + L + + + EI+ + I + L +
Sbjct: 2905 ITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSIND 2964
Query: 4654 AFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERG 4833
K QE+++ W L+ K RK L S + +F + E W+ M
Sbjct: 2965 KLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLP 3024
Query: 4834 KDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYA 5013
K ++ I++H++ + +I+ + +L+ + T +I ++++K +
Sbjct: 3025 KSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWT 3084
Query: 5014 GLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQ 5193
L + ++ W++ KE +++ G V+ LQ +
Sbjct: 3085 ELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHM 3144
Query: 5194 QFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQIL 5373
QF + E E++ LI + H D+ I ++ E LLE R +L
Sbjct: 3145 QFEKSLE-AQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLL 3203
Query: 5374 EASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVA 5553
E SRLL K + + + I EK DD RD S++ +KHQ++ +I A ++
Sbjct: 3204 EESRLLQKLLKNSYEVATWINEKNSIAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLD 3263
Query: 5554 QIERDAAE-LRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMV 5730
I+ + + +R+ + +A I SR E+ + W L C + ++L D F +
Sbjct: 3264 SIKSEGEKMIRERHYAPEA--IQSRLQEMEELWEELLASCQDKRAKLQDAYKALHFQRSI 3321
Query: 5731 RDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR 5910
D W+++V+ E+ + D+ + + + L+ +I + + ++ ++
Sbjct: 3322 EDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQE 3381
Query: 5911 KHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYL 6090
KH+ + E+E+++ +L + ++R L+ Y+F RD +W+ + P
Sbjct: 3382 KHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMA 3441
Query: 6091 ISKEYGRNLEETIKLIKKHEAFEKSAFAQE 6180
S++YG++L L +KH+ E +++
Sbjct: 3442 SSRDYGQSLATVQSLQEKHQNLENEISSRD 3471
Score = 233 bits (594), Expect = 5e-59
Identities = 206/1076 (19%), Positives = 456/1076 (42%), Gaps = 4/1076 (0%)
Frame = +1
Query: 1270 LTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQA 1449
+TE L+ ++G D+ SVE ++HE +E +I + + N
Sbjct: 2905 ITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSIND 2964
Query: 1450 KINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLG 1629
K+ +++ + R+ +L S +QK I+ + + L
Sbjct: 2965 KLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLP 3024
Query: 1630 AHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERS 1809
L + E ++++H + +I ER N+ Q+ N SG+ I +
Sbjct: 3025 KSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLAN------SGHYATP--EIHQSL 3076
Query: 1810 DVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTV 1989
LQK + EL+ E+ +L + L +F+ V + E + +E L++ D G + +V
Sbjct: 3077 SRLQKAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSV 3136
Query: 1990 SHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELS 2169
L KH E +L + +D + ++L SDNI R + KL E +
Sbjct: 3137 ESLQRKHMQFEKSLEAQMEKIDEMASFAQQLIQNKHYDSDNITNRCQAVLRRKEKLLENA 3196
Query: 2170 ASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDEL 2349
A+R+ L + ++ +V ++ + ++ +D +D +Q L+KH E+
Sbjct: 3197 AARRHLLEESRLLQKLLKNSYEVATWINEK-NSIAQDDSWRDPSNLQTKLQKHQSFQAEI 3255
Query: 2350 QNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDALSLY 2526
+ + ++ E + +E P+ I+ RL + EL Q ++ +L DA
Sbjct: 3256 MANKNRLDSIKSEGEKMIRERHYAPEAIQSRLQEMEELWEELLASCQDKRAKLQDAYKAL 3315
Query: 2527 KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLA 2706
+ E W+++ L D+ + + + LEQD+ + ++ + + A
Sbjct: 3316 HFQRSIEDTEKWLEDVENELKAPYSSDDLVVLNSHLKKQEELEQDIASHRDRLQELVNTA 3375
Query: 2707 RQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIE 2886
++ +H +D++ R ++L R+ LRD + ++R LE + F D E + W+
Sbjct: 3376 QEFQQEKHFLADELEERVDQLVQRYKSLRDPLQERRGSLEASRLQYEFFRDVDEELAWVH 3435
Query: 2887 DKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQA 3066
+K + D L+ V LQ + +E ++ + A ++ + R ++
Sbjct: 3436 EKLPMASSRD-YGQSLATVQSLQEKHQNLENEISSRDALTKAVLSTGQKLVRGGHSASRK 3494
Query: 3067 IREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQ 3246
I E +K + + L + +L ++ + +FL +L + WL + + + +
Sbjct: 3495 IMEQMKELETSVENLKAEAHVRRQRLMQSYEAHQFLTELLDVETWLAERSFILETSDYGK 3554
Query: 3247 SLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWE 3426
+ + LL + A + +++G+ +K++ G + ++ +P+ + +L + ++
Sbjct: 3555 NEESTQALLRKLEATKLDMEGFRPRIEKVQETGASLI-NKDNPESPAILSKLQRILADYQ 3613
Query: 3427 ELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQ 3606
L + + ++ L + L F R+ + + LS +++ DD Q L+ E K+ +
Sbjct: 3614 SLLQKAETQRKRLQEQFQLYQFEREFQLVDAWLSSKQSIAESDDYGQDLDGVEVLEKKFK 3673
Query: 3607 DFITTM-DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKL 3783
DF+ + K+ ++ +L +DGH D I K+ + I+E Q + L
Sbjct: 3674 DFVNEIKPLGHSKVLSLNELASKLEKDGHSKTDIIQKRTKQINEMWEKLCHAIQTRTENL 3733
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAANKERL 3960
+ A + Q+ D DE++ W++EK + Y D + + + + + +L A + L
Sbjct: 3734 RAAQQVHQYDHDVDEVKGWMQEKEAVVDIDDYGYDLPGVQTLLSQLEGVERDLGAIMKEL 3793
Query: 3961 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
++++ A +L P+ I ++ ++ W L+K E+ +L A + QLY
Sbjct: 3794 ERIRGEAWHLSRTYPQLKENIMERLTDVDECWRNLDKKFLERKARLSQAEQVQLYFNDCR 3853
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKK-AQHIDXXXXXXXXXXXX 4317
++ WA ++ + E+ D+ + +++ + E+ K+ ++ +
Sbjct: 3854 ELMAWANEMHALVISEELANDVLGAELLIKRHDEYKREIEKQWLKYEEIQRAGDDLTRNG 3913
Query: 4318 HPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISER 4485
H +E I+ L + E +++++ + R++ E R+++ + W++ +
Sbjct: 3914 HFMSVE-IEEKLLELSELMKKVKESWNVRKELYEENWEIQLLRRELEQAEAWLAAK 3968
Score = 229 bits (584), Expect = 7e-58
Identities = 304/1614 (18%), Positives = 633/1614 (38%), Gaps = 105/1614 (6%)
Frame = +1
Query: 1177 ELVLKEELIR---QEKLEQLAARFNRKAEMRETW------------LTENQRLVSQDNFG 1311
++V KE I Q+ L+QL R + + M+E L E Q LV+ + G
Sbjct: 566 QIVKKENSISKQWQDLLDQLQKRQHSLSTMQEILALLRDIDAIMEELKELQALVNSQDCG 625
Query: 1312 NDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXX 1491
L V +KH I+ I +Y+++ + + + +
Sbjct: 626 KQLLEVVDLLQKHNLIDLQISSYDDKLTHITQRTAEISKDSTVKAEVLYAKVPMLRQLYQ 685
Query: 1492 XXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHA 1671
R+ +LE ++ + + F + LG + + +QKH
Sbjct: 686 NLIAQSRTRKSQLEEALKLFEFFRDCKEEEAWISEKWKIARTTTLGKDVSQITASIQKHK 745
Query: 1672 LLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLA 1851
LE++ N ++ A R G D S P I ++ D LQ +++L D
Sbjct: 746 ALEAECN------SHRAICADVMRR--GWDLSQKNPTHEENIQKQRDKLQTLWQQLQDEV 797
Query: 1852 AERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNL 2031
A RK RL+ + Q++ D+ E ++E++ +++S D G+D + LL +H E +
Sbjct: 798 ANRKNRLQAAALIKQYFADIDEANSWLQERQTLVASKDYGKDESSAEALLHRHLRLEKEI 857
Query: 2032 RDLEKYLDRL----------------------DVSGKELQ----------DESIPGSDN- 2112
+ RL D++ K + + ++PGS +
Sbjct: 858 AAYSTEMRRLKEQAAIAAEQAPAAMVKTEAPDDLNQKTAKLPFSRTWATSESALPGSSSL 917
Query: 2113 ----IPPRLAEIRDYINKLKE----LSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRV 2268
+P + + +D I+ L E ++ RK+ L +EYY+F + + ++ + +
Sbjct: 918 DIHFVPENIWKTQDEIDSLYENLQSMAEDRKKALEEMIEYYRFCSSCEAFQSWMREKENI 977
Query: 2269 MSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHPDIRQRLD 2445
+ D V+++ +K+ EL + + + A + + ++ +I+ L
Sbjct: 978 FRTLQPQADN--VEVMQQKYQSFLTELAAGKGQLGEIESLATKFGKNSPGKYTEIQIWLK 1035
Query: 2446 TTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVE 2625
+ +E+L + + LI + D S+ + +K L L PG +E
Sbjct: 1036 EIHARWQHMESLKEEKGSELIGVADVRTFLEDCQSIGVLLQDKMGQLRNLEPGNSPAGLE 1095
Query: 2626 IMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVD 2805
K + +E+++ E K+ + +A+ + + S I + + + L+
Sbjct: 1096 SDKRKLSVVEREILVIERKIEYLRSVAKSIKDTNPAESKAITVQVENMESLLVNLKLETQ 1155
Query: 2806 QKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDL 2985
+KR+ L++A ++F D + + W E L S+ + D++ L R + +++
Sbjct: 1156 RKRDLLQQAQNQQSFLQDSRRLLLWAEGIREKLR-SEEMGVDVASAEHLLREHQDLLKEI 1214
Query: 2986 GAIQAKLDSLHKEADDIERERPQEAQA---------IREDIKRIHQVWDILNKKVREHEA 3138
+ + + L + I +++P ++ + E+ K + +W+ +
Sbjct: 1215 RSQKERFLQLEELGRKIIQKQPSNSRTRDVHLSVERLAEENKELENMWE-------QRWK 1267
Query: 3139 KLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHA-------AIRE 3297
KL + +LQ+F R+ D A L++ + + ++ + L QH ++
Sbjct: 1268 KLQDGLELQKFNREGDRINAALSSHEAFLRGDDLGDHVDAVRSLQKQHQEFEQLLMVLKR 1327
Query: 3298 EIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGL 3477
I+ + E+ + G + +++R+A L++ WE L R+ L L
Sbjct: 1328 RIEAFNENGADLIESGHFASHA--------IKERMATLRQRWERLVENNSKRKQRLLDSL 1379
Query: 3478 NLQMFLRDAKQAEVMLSQQENY-LAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAV 3654
LQ F RDA AE+++ +E Y +A D+ + +LK H+ M AN++ +
Sbjct: 1380 QLQEFNRDA--AELLIWMEEKYKIASDESYRDPTNVLRKLKWHEAAEKEMMANEKHFITL 1437
Query: 3655 GMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELR 3834
G+QL QD HYAA I KK ++++ K E KL+ A +Q + + +
Sbjct: 1438 IKKGNQLIQDDHYAAASIQKKMSELEKKWKELYGKMIERGDKLRQAGQQEQLMELLQDAK 1497
Query: 3835 EWIEE-KMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEY 4011
+ IE+ + + + ET D ++ +H+ ++E E+++ + A+ + + +
Sbjct: 1498 KKIEKIEKVLQEAETGHDLRSSRDLLKQHRQLENETHELAEKMNSIVSHAMKMATNHFDS 1557
Query: 4012 HGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK-EWATQLENEMTRE 4188
+D + ++ +++ L+ +E+ +KL +A DM+ W + +
Sbjct: 1558 QRILD-ETQKYLKRFESLQAPLDER-RKLLEAAVDLYEFYHYHDMELNWINERLPIASST 1615
Query: 4189 DQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQE 4368
+ L +QK + E+ Q + + I +
Sbjct: 1616 NCGKSLDVAQSLLQKHKEFQAEVNAHKQQVQRVLDKGRTMIVNQHPSAQKINEKCQELVT 1675
Query: 4369 QLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQK 4548
Q L+ ++R K L+ +F + D + WI+E+ L +++ G+ +L +
Sbjct: 1676 AWQGLEKACEERTKQLQHSVGFQEFLMNTSDLEAWIAEKRPLVMSKDYGKDEDGTLKLLQ 1735
Query: 4549 NLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKG 4728
++L +EI ++ I ++ + Q L G + +++ S +EL+E R
Sbjct: 1736 KHKVLEHEIAVYQDLIKELNESVQNLPAMGSIQYVEVDAPREQVHSRLRELQELAATRGK 1795
Query: 4729 DLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFAD 4908
L E+ H+FL + + + WM++Q+ ++ G + K++ + ++
Sbjct: 1796 KLDETLVLHEFLREYEDLQDWMAQQKQAASSEDYGNNYEHVLQLRAKYDTFRHQLEATGK 1855
Query: 4909 TIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHRE 5088
+ A + + +I+ +Q + + L + + +++
Sbjct: 1856 RVMTCQQLAENLLNAGHSESREIRQKQKDLRNSWEELLEITRLRGERLKDAEVIHKCYQD 1915
Query: 5089 IDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVAN--ANDGCDT 5262
+ D L I +K + +D VQ + A + E +G+E+ +
Sbjct: 1916 LTDALAHIEEKSKSI-PDDVAKDMRGVQT--QLRNHVALEHELLGNEQQLQDLIHSADHV 1972
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
L + A + + ++ W+ L + R ++LE + L++F D S E
Sbjct: 1973 LTRCSNEQASGLKAKQQAIVTNWKALKSKVQLRKELLEQAHKLYQFQAQVWDYFSWTSEM 2032
Query: 5443 THAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQI-----------ERDAAELRD 5586
M + RD S+ +HQ L +I A E+ QI E + E+R
Sbjct: 2033 IREMRAKETIRDISTSSLRLTQHQQLLAEIEAQEEKYNQIVQLGQSLLQDEEIRSKEIRQ 2092
Query: 5587 GYAG---------------DKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTS 5703
K LD +E K W HL L +++ L+ TS
Sbjct: 2093 KLQALLEEKDKVYSEWQQKKKWLDRIHQEQMFYKDWNHLDKLLNSQEEMLVFTS 2146
Score = 224 bits (572), Expect = 2e-56
Identities = 260/1420 (18%), Positives = 559/1420 (39%), Gaps = 66/1420 (4%)
Frame = +1
Query: 790 NKLKQDN-IQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEG 966
NKL++D + G +I ++ +++ K I + L+ A + L ++ +
Sbjct: 2590 NKLEKDGGLDGVQIQHKLDTILQRKKQIKNLSRSRREKLQ--TALLLALFYQNLAEAEDW 2647
Query: 967 VQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAW 1146
+ ++ + D Q+ P +K +L ++ + AN + +I D+N+
Sbjct: 2648 ISERMQKLEDPSIQD-PSNLQDKMKLLQKHQVFEAEILANEE---------IITDVNKKG 2697
Query: 1147 QSLEKAEHERELVLKEEL-IRQEKLEQL----AAR------------FNRKAEMRETWLT 1275
++L H + ++ ++ + QE+ E+L AAR F +K + E W+
Sbjct: 2698 EALVSMGHPKSGEIRRQVRMLQERWEKLKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIR 2757
Query: 1276 ENQRLVSQDNFGND----------LSSVEAATKKHEAIETDI------------FAY--- 1380
E + +++ + GND L+ AT ET++ Y
Sbjct: 2758 EKEVMINIGDVGNDYEHCLQLIRKLNEFRGATSGLPGEETEVSEEAICGCLLVYLVYFVA 2817
Query: 1381 ------------------EERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXX 1506
+ N + I +R++ +
Sbjct: 2818 VRNTEVHMEIDILETTVDDAHIKAINALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGN 2877
Query: 1507 XXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESD 1686
A R +LE ++ I + + + D G + VE+L+++H +E +
Sbjct: 2878 LNAYRRKLEGALEIHALIREIDDITERITEKSVLIQALDYGKDVESVENLIRRHEEMERE 2937
Query: 1687 INIIGERVNNSIAQAQRF--RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAER 1860
IN+I ++ ++ R RNP D K E ++ + L A +R
Sbjct: 2938 INVIKSKIEPLELESFRLSTRNPSINDKLTMKQQE----------MKNNWLRLQGQAKQR 2987
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
K +L + +L +F ++ E+ I+ ++ + + + ++ +H+ + +
Sbjct: 2988 KEKLAASYQLQKFNSEMKEITDWIQNIRGLMEAGGLPKSLNEAESMIEEHQQRKEEIEAR 3047
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
+ + L G++L + + I L+ ++ +L + + +L + +F+
Sbjct: 3048 VERFNSLSNYGQQLANSGHYATPEIHQSLSRLQKAWTELIQAWQEQYIKLFQAQDLQKFY 3107
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
+ + +L +++ED+G +V+ L +KH L+ + I + + A+ L
Sbjct: 3108 GYVEQTESWLSSKEAFLANEDLGDSVSSVESLQRKHMQFEKSLEAQMEKIDEMASFAQQL 3167
Query: 2401 PQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKG 2577
Q D I R L++K +L + R+ L ++ L KL ++ V +WI+EK
Sbjct: 3168 IQNKHYDSDNITNRCQAVLRRKEKLLENAAARRHLLEESRLLQKLLKNSYEVATWINEKN 3227
Query: 2578 KLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHR 2757
+A RD ++ + + + ++ + ++ ++ +++ H + I R
Sbjct: 3228 S-IAQDDSWRDPSNLQTKLQKHQSFQAEIMANKNRLDSIKSEGEKMIRERHYAPEAIQSR 3286
Query: 2758 QNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLS 2937
++ W +L KR +L+ A++ F+ ++T W+ED L+ + ++DL
Sbjct: 3287 LQEMEELWEELLASCQDKRAKLQDAYKALHFQRSIEDTEKWLEDVENELK-APYSSDDLV 3345
Query: 2938 GVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNK 3117
+ ++ +E+D+ + + +L L A + ++E+ A + E + ++ Q + L
Sbjct: 3346 VLNSHLKKQEELEQDIASHRDRLQELVNTAQEFQQEKHFLADELEERVDQLVQRYKSLRD 3405
Query: 3118 KVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIRE 3297
++E L+ + F RD+D AW+ +S + QSLA + L +H +
Sbjct: 3406 PLQERRGSLEASRLQYEFFRDVDEELAWVHEKLPMASSRDYGQSLATVQSLQEKHQNLEN 3465
Query: 3298 EIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGL 3477
EI K + + G ++ + + Q + L+ E L+ R+ L Q
Sbjct: 3466 EISSRDALTKAVLSTGQKLVRGGHSASRKIMEQ-MKELETSVENLKAEAHVRRQRLMQSY 3524
Query: 3478 NLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVG 3657
FL + E L+++ L D ++ E + L++ + M+ +I V
Sbjct: 3525 EAHQFLTELLDVETWLAERSFILETSDYGKNEESTQALLRKLEATKLDMEGFRPRIEKVQ 3584
Query: 3658 MFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELRE 3837
G L + + I K + I + +KA+ K+L++ L QF + +
Sbjct: 3585 ETGASLINKDNPESPAILSKLQRILADYQSLLQKAETQRKRLQEQFQLYQFEREFQLVDA 3644
Query: 3838 WIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSEL-AANKERLDQLKHAAINLGDDKPEY 4011
W+ K A+ + Y +D + + + F +E+ ++ L A L D
Sbjct: 3645 WLSSKQSIAESDDYGQDLDGVEVLEKKFKDFVNEIKPLGHSKVLSLNELASKLEKDGHSK 3704
Query: 4012 HGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTRED 4191
I + +++ W++L + + + L A + Y + ++K W + E + +D
Sbjct: 3705 TDIIQKRTKQINEMWEKLCHAIQTRTENLRAAQQVHQYDHDVDEVKGWMQEKEAVVDIDD 3764
Query: 4192 QPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQ 4371
DL V + + +E ++ + ++ +P ENI V E
Sbjct: 3765 YGYDLPGVQTLLSQLEGVERDLGAIMKELERIRGEAWHLSRTYPQLKENIMERLTDVDEC 3824
Query: 4372 LQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKN 4551
+ L +R+ L + + + D + W +E L ++ L + L K
Sbjct: 3825 WRNLDKKFLERKARLSQAEQVQLYFNDCRELMAWANEMHALVISEELANDVLGAELLIKR 3884
Query: 4552 LQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGD 4731
EI+ +I G +L GH E+K+ EL +++KE+ RK
Sbjct: 3885 HDEYKREIEKQWLKYEEIQRAGDDLTRNGHFMSVEIEEKLLELSELMKKVKESWNVRKEL 3944
Query: 4732 LGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFST 4851
E+ + + +AEAW++ +E ++ G + ST
Sbjct: 3945 YEENWEIQLLRRELEQAEAWLAAKESFLSDPSYGVSKDST 3984
Score = 202 bits (513), Expect = 1e-49
Identities = 204/1041 (19%), Positives = 443/1041 (41%), Gaps = 13/1041 (1%)
Frame = +1
Query: 1159 KAEHERELVLKEELIRQEKLEQLAARFNRKAEMRET-----WLTENQRLVSQDNFGNDLS 1323
+ E+ L++ +L Q K + L N+++ ++++ W + + + G D++
Sbjct: 1139 QVENMESLLVNLKLETQRKRDLLQQAQNQQSFLQDSRRLLLWAEGIREKLRSEEMGVDVA 1198
Query: 1324 SVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK--INERKENVXXXXXXX 1497
S E ++H+ + +I + +ER + ++ E +
Sbjct: 1199 SAEHLLREHQDLLKEIRSQKERFLQLEELGRKIIQKQPSNSRTRDVHLSVERLAEENKEL 1258
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
R +L+ + +QK ++ L +DLG H+ V L ++H
Sbjct: 1259 ENMWEQRWKKLQDGLELQKFNREGDRINAALSSHEAFLRGDDLGDHVDAVRSLQKQHQEF 1318
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E + ++ R+ N +G D I ER L++R++ L++ ++
Sbjct: 1319 EQLLMVLKRRIEAF--------NENGADLIESGHFASHAIKERMATLRQRWERLVENNSK 1370
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
RK+RL D+ +L +F D AEL ++E+ ++ +S ++ RD V L H+ AE +
Sbjct: 1371 RKQRLLDSLQLQEFNRDAAELLIWMEEKYKI-ASDESYRDPTNVLRKLKWHEAAEKEMMA 1429
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
EK+ L G +L + + +I +++E+ +L R ++L + Q
Sbjct: 1430 NEKHFITLIKKGNQLIQDDHYAAASIQKKMSELEKKWKELYGKMIERGDKLRQAGQQEQL 1489
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES 2397
D + + +V+ + G D + + LLK+H + +E + + + + A
Sbjct: 1490 MELLQDAKKKIEKIEKVLQEAETGHDLRSSRDLLKQHRQLENETHELAEKMNSIVSHAMK 1549
Query: 2398 LPQEAREHPDIRQRLDTTLKQKAELENLS---QLRKQRLIDALSLYKLYSDADSVESWID 2568
+ A H D ++ LD T K E+L R++ L A+ LY+ Y D +WI+
Sbjct: 1550 M---ATNHFDSQRILDETQKYLKRFESLQAPLDERRKLLEAAVDLYEFYHYHDMELNWIN 1606
Query: 2569 EKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDI 2748
E+ + ++ G+ ++ + + + + ++ + +V V D R ++ +HP++ I
Sbjct: 1607 ERLPIASSTNCGKSLDVAQSLLQKHKEFQAEVNAHKQQVQRVLDKGRTMIVNQHPSAQKI 1666
Query: 2749 LHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTN 2928
+ +L W L +++ +L+ + + F ++ + WI +K R L S
Sbjct: 1667 NEKCQELVTAWQGLEKACEERTKQLQHSVGFQEFLMNTSDLEAWIAEK-RPLVMSKDYGK 1725
Query: 2929 DLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDI 3108
D G +KL ++ ++E ++ Q + L++ ++ + + +++H
Sbjct: 1726 DEDGTLKLLQKHKVLEHEIAVYQDLIKELNESVQNLPAMGSIQYVEVDAPREQVHSRLRE 1785
Query: 3109 LNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAA 3288
L + KLDE L FLR+ + Q W+ ++ +SE+ + QL ++
Sbjct: 1786 LQELAATRGKKLDETLVLHEFLREYEDLQDWMAQQKQAASSEDYGNNYEHVLQLRAKYDT 1845
Query: 3289 IREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLS 3468
R +++ + + + + + + + +RQ+ L+ WEEL + R L
Sbjct: 1846 FRHQLEATGKRVMTCQQLAENLL-NAGHSESREIRQKQKDLRNSWEELLEITRLRGERLK 1904
Query: 3469 QGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIR 3648
+ +D A + ++ + DD+ + + + QL+ H + N+++++
Sbjct: 1905 DAEVIHKCYQDLTDALAHIEEKSKSI-PDDVAKDMRGVQTQLRNHVALEHELLGNEQQLQ 1963
Query: 3649 AVGMFGDQ-LCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCD 3825
+ D L + + A + K + I A + K Q + L+ A L QF +
Sbjct: 1964 DLIHSADHVLTRCSNEQASGLKAKQQAIVTNWKALKSKVQLRKELLEQAHKLYQFQAQVW 2023
Query: 3826 ELREWIEEKMIRAQ--DETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDD 3999
+ W E MIR ET RD T + + +HQ +E+ A +E+ +Q+ +L D
Sbjct: 2024 DYFSWTSE-MIREMRAKETIRDISTSSLRLTQHQQLLAEIEAQEEKYNQIVQLGQSLLQD 2082
Query: 4000 KPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEM 4179
+ I +++ L + D++ ++K + L +++Q++ K+W L+ +
Sbjct: 2083 EEIRSKEIRQKLQALLEEKDKVYSEWQQKKKWLDRIHQEQMF------YKDW-NHLDKLL 2135
Query: 4180 TREDQPGDLTTVNVAMQKQHL 4242
+++ T+V+ A+ L
Sbjct: 2136 NSQEEMLVFTSVSKAVSVYRL 2156
Score = 181 bits (459), Expect = 2e-43
Identities = 141/644 (21%), Positives = 285/644 (43%), Gaps = 50/644 (7%)
Frame = +1
Query: 4483 RLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFE 4662
++V K+ +LG S+ + +L + + + + + I + +L +G +G +
Sbjct: 2545 QVVYLKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGVQIQ 2604
Query: 4663 KKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDE 4842
K+ + +++K + R+ L + F + EAE W+SE+ + ++D +D
Sbjct: 2605 HKLDTILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISER-MQKLEDPSIQDP 2663
Query: 4843 FSTKNQIK---KHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYA 5013
+ ++++K KH+ +++I + I + K V P + +I+ + +++ +
Sbjct: 2664 SNLQDKMKLLQKHQVFEAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQERWE 2723
Query: 5014 GLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQ 5193
L+ +++D + WI +KEV+ + G DYEH L +
Sbjct: 2724 KLKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLIRKLN 2783
Query: 5194 QFARDTENIGSERVANAND---GC-----------------------DTLIGHGHTDA-- 5289
+F T + E + + GC +T + H A
Sbjct: 2784 EFRGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHIKAIN 2843
Query: 5290 --------------PTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLS 5427
TI + LNE W + ++ + LE + +H + D
Sbjct: 2844 ALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREIDDITE 2903
Query: 5428 RIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL--RDGYAG 5598
RI EK+ + D G+D SV L R+H+ ++I I ++ +E ++ L R+
Sbjct: 2904 RITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEPLELESFRLSTRNPSIN 2963
Query: 5599 DKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNS 5778
DK + ++ E+ W L+G R +L + L KF + ++++ W+ ++ M +
Sbjct: 2964 DK---LTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQNIRGLMEA 3020
Query: 5779 QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT 5958
PK ++ E ++ HQ K EI+AR E FN+ + G+ L N HYA+ EI + L +L
Sbjct: 3021 GGLPKSLNEAESMIEEHQQRKEEIEARVERFNSLSNYGQQLANSGHYATPEIHQSLSRLQ 3080
Query: 5959 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
E+++ W++++ L ++ +F ESWL ++E +L +++ G ++ L
Sbjct: 3081 KAWTELIQAWQEQYIKLFQAQDLQKFYGYVEQTESWLSSKEAFLANEDLGDSVSSVESLQ 3140
Query: 6139 KKHEAFEKSAFAQEERFLALEKLTTF--ELKETQHREEETAKRR 6264
+KH FEKS AQ E+ ++++ +F +L + +H + + R
Sbjct: 3141 RKHMQFEKSLEAQMEK---IDEMASFAQQLIQNKHYDSDNITNR 3181
Score = 63.5 bits (153), Expect = 7e-08
Identities = 97/522 (18%), Positives = 196/522 (36%), Gaps = 53/522 (10%)
Frame = +1
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
M Q +Y+ + G + I+KHE + + + I +L +A+K ++
Sbjct: 2542 MPIQVVYLKSSDLGSSVDEVEQLIRKHEAFEKLLASQDEKITSLQEQANKLEKDGGLDGV 2601
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADK--EVVAGSQE 5145
QIQ + I + +++ ++ + + WI+++ ++ S +
Sbjct: 2602 QIQHKLDTILQRKKQIKNLSRSRREKLQTALLLALFYQNLAEAEDWISERMQKLEDPSIQ 2661
Query: 5146 NGQDYEHVQMLQERFQQFARDTENIGSERV-ANANDGCDTLIGHGHTDAPTIALWKDSLN 5322
+ + + L ++ Q F + E + +E + + N + L+ GH + I L
Sbjct: 2662 DPSNLQDKMKLLQKHQVF--EAEILANEEIITDVNKKGEALVSMGHPKSGEIRRQVRMLQ 2719
Query: 5323 EAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALS 5499
E WE L + R ++LE SR +F + I EK + D+G D L
Sbjct: 2720 ERWEKLKRAVAARGKMLEDSRDFLEFLQKVDQVEAWIREKEVMINIGDVGNDYEHCLQLI 2779
Query: 5500 RKHQN--------------------------YLKDIAAIGEQVAQIERDAAELRDGYAGD 5601
RK YL A+ +E D E A
Sbjct: 2780 RKLNEFRGATSGLPGEETEVSEEAICGCLLVYLVYFVAVRNTEVHMEIDILETTVDDAHI 2839
Query: 5602 KALD----------------IGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVR 5733
KA++ I R ++ + W G +A +L ++ + +
Sbjct: 2840 KAINALAMKLERQNKEETKTIYQRRKQLNEKWNSFHGNLNAYRRKLEGALEIHALIREID 2899
Query: 5734 DLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRK 5913
D+ + E + + + KDV VE L+ H+ ++ EI+ + + L L+ +
Sbjct: 2900 DITERITEKSVLIQALDYGKDVESVENLIRRHEEMEREINVIKSKIEP-LELESFRLSTR 2958
Query: 5914 HYASSEIEKKLIKLTTERAEMMRRW-------EDRWEYLQLILEVYQFARDAAVAESWLF 6072
+ + ++ KLT ++ EM W + R E L ++ +F + W+
Sbjct: 2959 NPSIND------KLTMKQQEMKNNWLRLQGQAKQRKEKLAASYQLQKFNSEMKEITDWIQ 3012
Query: 6073 AQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL 6198
+ + ++L E +I++H+ ++ A+ ERF +L
Sbjct: 3013 NIRGLMEAGGLPKSLNEAESMIEEHQQRKEEIEARVERFNSL 3054
>gi|226515|prf||1516310A beta spectrin
Length = 800
Score = 966 bits (2498), Expect = 0.0
Identities = 489/789 (61%), Positives = 599/789 (74%), Gaps = 1/789 (0%)
Frame = +1
Query: 16 GNSGAYTQDEDYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDL 192
G Y + +YD NSS+RLFERSRIKALA+ERE VQKKTFTKWVNSHL RV+C++ DL
Sbjct: 15 GPGNEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADL 74
Query: 193 YMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDI 372
Y+DMRDGK L++LL VLSGERLPKPT GKMRIHCLENV+K LQFLR Q VHLEN+GSHDI
Sbjct: 75 YVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDI 134
Query: 373 VDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNF 552
VDGN+ L LGLIWTIILRFQIQDIT E+ DN ET+SAK+ALLLWCQMKTAGY NVNV+NF
Sbjct: 135 VDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNF 194
Query: 553 STSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNV 732
+TSWRDGLAFNA+IHKHRPDLV ++ L K+NA++NL +AFD AE++LGLAK LDAEDV V
Sbjct: 195 TTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFV 254
Query: 733 DQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWI 912
+ PDEKSIITYVVTYYHYF+KLKQ+ +QGKRIGKV+ MENDKM++ YE +SDLL+WI
Sbjct: 255 EHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWI 314
Query: 913 NAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQ 1092
IQ L ER FEN+L GVQ QL +F++YRT EKPPKF EKG LEVLLFTLQS MRANNQ
Sbjct: 315 ETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQ 374
Query: 1093 RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWL 1272
+P+ P+EGK+I+DIN+AW+ LEKAEHEREL L+EELIRQEKLEQLAARF+RKA MRETWL
Sbjct: 375 KPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWL 434
Query: 1273 TENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK 1452
+ENQRLVSQDNFG DL++VEAA KKHEAIETDIFAYEER YHD +
Sbjct: 435 SENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKR 494
Query: 1453 INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGA 1632
I RK+NV ARR+RLE+S+ +Q+ F IK L+++D G
Sbjct: 495 ILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGK 554
Query: 1633 HLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSD 1812
HLM VEDLLQKH+L+E+DINI+GERV + +Q+F + D YKP +P I R
Sbjct: 555 HLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLS---DDPESYKPCDPEIIVSRVQ 611
Query: 1813 VLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
L+ Y EL+ LA ER+ RLE++++L QF+WD A+ E+ IKE+EQ++S+ + G D+ TV+
Sbjct: 612 QLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVN 671
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSA 2172
+L+KHK E+ + + L + G EL E G+D I RL EI + + L +L+
Sbjct: 672 LMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTK 731
Query: 2173 SRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQ 2352
R++RL VEY+Q F DADDVD ++ DTLR++SSEDVG+DE VQ LLKKH DV DEL+
Sbjct: 732 YRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELK 791
Query: 2353 NFDQHIKVL 2379
N+ + I L
Sbjct: 792 NYAEVIDAL 800
Score = 112 bits (280), Expect = 1e-22
Identities = 88/353 (24%), Positives = 164/353 (45%), Gaps = 5/353 (1%)
Frame = +1
Query: 5107 WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTD 5286
W+++ + + G D V+ ++ + D ERV CD L + D
Sbjct: 433 WLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAY-EERVQAVVAVCDELESERYHD 491
Query: 5287 APTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME-KTHAMPDD 5463
I L KD++ W LLEL+ R LE S L + + + L + E K M DD
Sbjct: 492 VKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDD 551
Query: 5464 LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAE-LRDGYAGDKALD---IGSRES 5631
G+ V L +KH DI +GE+V + +++ + L D K D I SR
Sbjct: 552 YGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQ 611
Query: 5632 EVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE 5811
++ A+ L L R SRL ++ L++F D W+ E ++ +++ E D++ V
Sbjct: 612 QLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVN 671
Query: 5812 LLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWE 5991
L+++ H++L++EI + + +G +L+ H+ + I+ +L ++ + ++ +
Sbjct: 672 LMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTK 731
Query: 5992 DRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHE 6150
R + L+ +E +Q DA ++W+ + S++ GR+ L+KKH+
Sbjct: 732 YRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHK 784
Score = 110 bits (274), Expect = 6e-22
Identities = 85/416 (20%), Positives = 191/416 (45%), Gaps = 15/416 (3%)
Frame = +1
Query: 2767 LNARWAQLRDMVDQK----RNELERAHRLETF--RIDCQETV--TWIEDKTRVLEDSDAL 2922
+N W +L ++ R EL R +LE R D + ++ TW+ + R++ D
Sbjct: 388 INKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQ-DNF 446
Query: 2923 TNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVW 3102
DL+ V ++ +E D+ A + ++ ++ D++E ER + + I + ++W
Sbjct: 447 GFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLW 506
Query: 3103 DILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQH 3282
L + +R +L+ + LQ+ +++ + + ++ + +++ + L E LL +H
Sbjct: 507 TYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKH 566
Query: 3283 AAIREEIDGYAEDYKKMRAMGDRVTQDQT------DPQYMFLRQRLAGLQEGWEELQRMW 3444
+ + +I+ E K + + D DP+ + R+ L++ + EL R+
Sbjct: 567 SLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIV--SRVQQLEDAYAELVRLA 624
Query: 3445 DNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTM 3624
R+ L + L F D E + ++E ++ D++ L L +H+ + +
Sbjct: 625 VERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEI 684
Query: 3625 DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQ 3804
++D +++ V G +L +GH+ AD+I + + I + + + ++L++A+
Sbjct: 685 TSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYF 744
Query: 3805 QFLSDCDELREWIEEKM-IRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL 3969
Q +D D++ W+ + + I + ++ RD + S +H+ EL E +D L
Sbjct: 745 QLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDAL 800
Score = 109 bits (272), Expect = 1e-21
Identities = 83/369 (22%), Positives = 180/369 (48%), Gaps = 9/369 (2%)
Frame = +1
Query: 2239 DRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEARE 2418
+ +L + R++S ++ G D V+ KKH+ + ++ +++ ++ + A + L E+
Sbjct: 431 ETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDEL--ESER 488
Query: 2419 HPDIRQ---RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLA 2589
+ D+++ R D ++ L L + R+ RL +L L + + + + ++E +LL
Sbjct: 489 YHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLM 548
Query: 2590 TLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNS------DDIL 2751
T G+ + VE + + +E D+ +V V +++ L+ + P S + I+
Sbjct: 549 TDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLS-DDPESYKPCDPEIIV 607
Query: 2752 HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTND 2931
R +L +A+L + ++R+ LE + +L F D + WI++K +++ +D + +D
Sbjct: 608 SRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVS-TDEVGHD 666
Query: 2932 LSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDIL 3111
L+ V + + +E ++ + +L ++ K ++ E A I++ +K I WD L
Sbjct: 667 LTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHL 726
Query: 3112 NKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAI 3291
+ +L+ A + + D D W+ T R V+SE+ + A + LL +H +
Sbjct: 727 LDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDV 786
Query: 3292 REEIDGYAE 3318
+E+ YAE
Sbjct: 787 ADELKNYAE 795
Score = 108 bits (269), Expect = 2e-21
Identities = 99/491 (20%), Positives = 208/491 (42%), Gaps = 6/491 (1%)
Frame = +1
Query: 3469 QGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIR 3648
Q L + F + L+Q NY + P+ +E+ ++ + M AN++K
Sbjct: 319 QSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFT-LQSKMRANNQKPY 377
Query: 3649 AVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
++ D + A +++ K ER A RE E++++ K +F
Sbjct: 378 TPKE--GKMISDINKAWERLEKAEH---ERELALRE---ELIRQEKLEQLAARFDRKASM 429
Query: 3829 LREWIEEKM-IRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
W+ E + +QD D + + +H+A ++++ A +ER+ + L ++
Sbjct: 430 RETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERY 489
Query: 4006 EYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTR 4185
I + + + W L + + +L + + Q Q + + + +++ +
Sbjct: 490 HDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMT 549
Query: 4186 EDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQ 4365
+D L V +QK L+E ++ + + P+ + + +
Sbjct: 550 DDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSR 609
Query: 4366 -EQLQRLQAPLD----DRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPD 4530
+QL+ A L +RR LE + +QF D DE+ WI E+ + +G L
Sbjct: 610 VQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTT 669
Query: 4531 CHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEA 4710
+ + + L +EI +H+P + + G ELI EGH + +++E+ + W L +
Sbjct: 670 VNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDL 729
Query: 4711 VKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSD 4890
K R+ L + + Q D + + WM + + ++ G+DE + ++ +KKH+ + +
Sbjct: 730 TKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADE 789
Query: 4891 IDKFADTIRAL 4923
+ +A+ I AL
Sbjct: 790 LKNYAEVIDAL 800
Score = 106 bits (264), Expect = 9e-21
Identities = 110/492 (22%), Positives = 205/492 (41%), Gaps = 45/492 (9%)
Frame = +1
Query: 1675 LESDINIIGER--------VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQ--- 1821
+E+ I +GER V +AQ +R + P K VE G ++ LQ
Sbjct: 314 IETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPP----KFVEKGNLEVLLFTLQSKM 369
Query: 1822 ----------KRYKELLDL--AAERKRRLEDNKRLC----------------QFWWDVAE 1917
K K + D+ A ER + E + L +F +
Sbjct: 370 RANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASM 429
Query: 1918 LEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESI 2097
E + E ++++S + G D+ V KH+ E ++ E+ + + EL+ E
Sbjct: 430 RETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERY 489
Query: 2098 PGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSS 2277
I R + L EL +R+ RL ++ Q F + + + + +++ +
Sbjct: 490 HDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMT 549
Query: 2278 EDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREH-----PDIR-QR 2439
+D GK V+ LL+KH V ++ + +KV+ ++ + E P+I R
Sbjct: 550 DDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSR 609
Query: 2440 LDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEE 2619
+ AEL L+ R+ RL ++ L++ Y D E+WI EK ++++T G D+
Sbjct: 610 VQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTT 669
Query: 2620 VEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDM 2799
V +M + LE ++ + + ++ NV + +L+ H +D I R ++ +W L D+
Sbjct: 670 VNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDL 729
Query: 2800 VDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMER 2979
+R LE A D + W+ D R++ D + D + V L ++ +
Sbjct: 730 TKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSED-VGRDEANVQSLLKKHKDVAD 788
Query: 2980 DLGAIQAKLDSL 3015
+L +D+L
Sbjct: 789 ELKNYAEVIDAL 800
Score = 105 bits (263), Expect = 1e-20
Identities = 98/424 (23%), Positives = 184/424 (43%), Gaps = 15/424 (3%)
Frame = +1
Query: 4651 PAFEKKIQELRSAWQELKEAVKDRKGDLGES--------EKAHQFLYDCGEAEAWMSEQE 4806
P K I ++ AW+ L++A +R+ L E + A +F E W+SE +
Sbjct: 379 PKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQ 438
Query: 4807 LYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVR 4986
+ QD G D + + KKHE +++DI + + ++A+ + E+ ++I +R
Sbjct: 439 RLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLR 498
Query: 4987 QAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEH 5166
+ + +L+ L + +E+ +L + + + + + + G+
Sbjct: 499 KDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMG 558
Query: 5167 VQMLQERFQQFARDTENIGSERVANANDGCDTLIG-----HGHTDAPTIALWKDSLNEAW 5331
V+ L ++ D NI ERV + + D I L +A+
Sbjct: 559 VEDLLQKHSLVEADI-NILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAY 617
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKH 5508
L+ L R LE SR L +FY D D + I EK + D++G D ++V + KH
Sbjct: 618 AELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKH 677
Query: 5509 QNYLKDIAAIGEQVAQIERDAAEL-RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTS 5685
+ +I + Q+ + + +EL +G+ G A I R E++ W HL L R
Sbjct: 678 KALESEITSHDPQLQNVAKVGSELITEGHFG--ADRIKDRLKEILNKWDHLLDLTKYRRQ 735
Query: 5686 RLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREE 5865
RL + + F+ D+ WM + R ++S++ +D + V+ L+ H+ + E+ E
Sbjct: 736 RLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAE 795
Query: 5866 NFNA 5877
+A
Sbjct: 796 VIDA 799
Score = 94.7 bits (234), Expect = 3e-17
Identities = 91/417 (21%), Positives = 180/417 (42%), Gaps = 22/417 (5%)
Frame = +1
Query: 4033 IEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA-------DMKE-WATQLENEMTRE 4188
I ++ W+ LEK E+ L + +Q ++ +A M+E W ++ + ++++
Sbjct: 385 ISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQD 444
Query: 4189 DQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHR----L 4356
+ DL V A +K IET++ + + DELE+ + H L
Sbjct: 445 NFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVC--------DELESERYHDVKRIL 496
Query: 4357 AVQEQLQRLQAPLDDRRKALE-RKKAAFQFGRDVDDEKLWISERLV----LAKAQNLGES 4521
++ + RL L + +A R + + Q ++ E L+I + + L + G+
Sbjct: 497 LRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQ-EMLYILDNMEEIKQLLMTDDYGKH 555
Query: 4522 LPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI-DEGHANGPA----FEKKIQELRS 4686
L L + L+ +I+ + + N Q+ + D+ + P ++Q+L
Sbjct: 556 LMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLED 615
Query: 4687 AWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIK 4866
A+ EL +R+ L ES K QF +D + E W+ E+E + DE G D + +
Sbjct: 616 AYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLS 675
Query: 4867 KHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXX 5046
KH+ L+S+I ++ +A + + E ++I+ R +I + L D
Sbjct: 676 KHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQ 735
Query: 5047 XXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTEN 5217
+ L + DD+ W+ D + S++ G+D +VQ L ++ + A + +N
Sbjct: 736 RLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKN 792
Score = 75.1 bits (183), Expect = 2e-11
Identities = 62/255 (24%), Positives = 119/255 (46%), Gaps = 5/255 (1%)
Frame = +1
Query: 5458 DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEV 5637
D+ G D ++V A ++KH+ DI A E+V + EL D I R+ V
Sbjct: 444 DNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHD-VKRILLRKDNV 502
Query: 5638 VKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELL 5817
++ W +L L AR RL + L + + +L M+E+K+ + + + K + GVE L
Sbjct: 503 MRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDL 562
Query: 5818 MNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLI-----KLTTERAEMMR 5982
+ H ++A+I+ E + + L+ + + ++I +L AE++R
Sbjct: 563 LQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAYAELVR 622
Query: 5983 RWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
+R L+ +++QF D A E+W+ +E + + E G +L ++ KH+A E
Sbjct: 623 LAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALES 682
Query: 6163 SAFAQEERFLALEKL 6207
+ + + + K+
Sbjct: 683 EITSHDPQLQNVAKV 697
Score = 45.4 bits (106), Expect = 0.019
Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 16/177 (9%)
Frame = +1
Query: 5716 FMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSLKAEIDAREE-NFNACI 5883
+ N DLL W++ + + +E ++GV+ +N+++++ E+ N +
Sbjct: 303 YENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLL 362
Query: 5884 SLGRDLL---NRKHYAS------SEIEK---KLIKLTTERAEMMRRWEDRWEYLQLILEV 6027
+ + N+K Y S+I K +L K ER +R R E L+ +
Sbjct: 363 FTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAA- 421
Query: 6028 YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL 6198
+F R A++ E+WL + + +G +L KKHEA E FA EER A+
Sbjct: 422 -RFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAV 477
>gi|11602887|gb|AAF93171.1| betaIV spectrin isoform sigma2 [Homo
sapiens]
Length = 1304
Score = 936 bits (2420), Expect = 0.0
Identities = 533/1266 (42%), Positives = 765/1266 (60%), Gaps = 30/1266 (2%)
Frame = +1
Query: 31 YTQDEDYDDNSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRD 210
+ +++ ++A LFE SRIKALADERE VQKKTFTKWVNSHL RV C + DLY+D+RD
Sbjct: 32 WEREQPAASTAAASLFECSRIKALADEREAVQKKTFTKWVNSHLARVGCHIGDLYVDLRD 91
Query: 211 GKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSR 390
G +L RLL VLSGE+LP+PT G+MRIH LENV+K LQFL+ Q VHLEN+GSHDIVDGN R
Sbjct: 92 GFVLTRLLEVLSGEQLPRPTRGRMRIHSLENVDKALQFLKEQRVHLENVGSHDIVDGNHR 151
Query: 391 LTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRD 570
LTLGL+WTIILRFQIQ I E DN ETRSAK+ALLLWCQMKTAGYP VN++NF+TSWRD
Sbjct: 152 LTLGLVWTIILRFQIQVIKIETEDNRETRSAKDALLLWCQMKTAGYPEVNIQNFTTSWRD 211
Query: 571 GLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEK 750
GLAFNALIH+HRPDLVD+ L KSNA YNLQ AF TAE LGLA+ LD EDVN++ PDEK
Sbjct: 212 GLAFNALIHRHRPDLVDFSKLTKSNANYNLQRAFRTAEQHLGLARLLDPEDVNMEAPDEK 271
Query: 751 SIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQL 930
SIITYVV++YHYF+K+K ++GKRIGKV+++++E K+I RYE L+++LL WI+ + L
Sbjct: 272 SIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELLAWIHRTVGL 331
Query: 931 LNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPR 1110
++ + F N+L GVQ+QL F Y T EKP KF EKG LEVLLF++QS +RA N+R FVPR
Sbjct: 332 ISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEKGNLEVLLFSIQSKLRACNRRLFVPR 391
Query: 1111 EGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRL 1290
EG I DI++AW LEKAEHERE L+ ELIRQEKLE LA RF+ K MRE+WL ENQRL
Sbjct: 392 EGCGIWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRL 451
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
VSQDNFG +L +VEAA KKHEAIE DI AYEER Y+D ++ +++
Sbjct: 452 VSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRD 511
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+V ARR RLE ++A+QK+F ++++LLS + G HL++ +
Sbjct: 512 SVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEAD 571
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
DLLQKH LLE DI ERV A A RF +P +P I R + +
Sbjct: 572 DLLQKHGLLEGDIAAQSERVEALNAAALRFS----------QPCDPQVICNRVNHVHGCL 621
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG------------- 1971
EL + AA R+ LE ++ L ++ E E +++E++L + G
Sbjct: 622 AELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAG 681
Query: 1972 --RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES---IPGSDNI-----PP 2121
D+ + + LLA+HK + L L + G+EL PG+D +
Sbjct: 682 GAHDLSSTARLLAQHKILQGELGGRRASLQQALRCGEELVAAGGAVGPGADTVHLVGLAE 741
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R A R +L+E +A R+ RL +QF D D + +L D R+ ++ D G DE
Sbjct: 742 RAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEA 801
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQRLDTTLKQKAEL 2472
+ + L ++H + E++ + L + +L + P ++ R+ + AE+
Sbjct: 802 SSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEV 861
Query: 2473 ENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTL 2652
++ LR+Q L DAL++Y+++ + + E WI EK + L ++ +++VE+++HRF++L
Sbjct: 862 TEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESL 921
Query: 2653 EQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA 2832
+Q+M + +V +VN ++L+ HP+SD++ Q+ LN+RW ++ ++V+Q++ E+
Sbjct: 922 DQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAV 981
Query: 2833 HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDS 3012
+E ++ E + +K R +E + LQ RLS +E L A++ + +
Sbjct: 982 LLVENHVLEVAEVRAQVREKRRAVESAPRAGG------ALQWRLSGLEAALQALEPRQAA 1035
Query: 3013 LHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
L +EA + P +A + + + + W L + + AG LQRFL DLD F
Sbjct: 1036 LLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAF 1095
Query: 3193 QAWLTATQRQVASEEE--PQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR-VTQD 3363
WL Q E P SL EA+ LL +HAA++EE+D EDY ++ A + + D
Sbjct: 1096 LDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDYARIVAASEALLAAD 1155
Query: 3364 QTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQEN 3540
+ + L + L L+ GW +L +W R+ L Q Q+FLRD +QA V+L QE
Sbjct: 1156 GAELGPGLALDEWLPHLELGWHKLLGLWKARRKALVQAHIYQLFLRDLRQALVVLRNQEM 1215
Query: 3541 YLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKA 3720
L+ ++P ++E E LK+H+DF+TTM+ + +K++ + L + G+ ++ +
Sbjct: 1216 ALSGAELPGTVESVEEALKQHRDFLTTMELSQQKMQVAVQAAEGLLRQGNIYGEQAQEAV 1275
Query: 3721 RNIDER 3738
+ E+
Sbjct: 1276 TRLLEK 1281
Score = 159 bits (402), Expect = 9e-37
Identities = 171/841 (20%), Positives = 331/841 (39%), Gaps = 33/841 (3%)
Frame = +1
Query: 3733 ERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKM-IRAQDETYRDAKTITSKF 3909
ER A R E++++ K L Q+F W+ E + +QD + + +
Sbjct: 412 EREAALRA---ELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQDNFGYELPAVEAAM 468
Query: 3910 VRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKG 4089
+H+A ++++AA +ER+ + A L + + Q + + QW L +
Sbjct: 469 KKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRDSVLRQWALLTGLVGARR 528
Query: 4090 QKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKA 4269
+L Q Q + M +W +++ ++ + L + +QK L+E ++ ++
Sbjct: 529 TRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEADDLLQKHGLLEGDIAAQS 588
Query: 4270 QHIDXXXXXXXXXXXX-HPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFG 4446
+ ++ P + N H V L LQ RR LE ++ +
Sbjct: 589 ERVEALNAAALRFSQPCDPQVICNRVNH---VHGCLAELQEQAARRRAELEASRSLWALL 645
Query: 4447 RDVDDEKLWISERLVLAKAQNLG---------------ESLPDCHRLQKNLQLLSNEIDN 4581
+++++ + W ++ L +A G L RL ++L E+
Sbjct: 646 QELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAGGAHDLSSTARLLAQHKILQGELGG 705
Query: 4582 HEPWINQICNNGQELIDEGHANGPAFE--------KKIQELRSAWQELKEAVKDRKGDLG 4737
+ Q G+EL+ G A GP + ++ R WQ L+EA R+ L
Sbjct: 706 RRASLQQALRCGEELVAAGGAVGPGADTVHLVGLAERAASARRRWQRLEEAAARRERRLQ 765
Query: 4738 ESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIR 4917
E+ HQF D W+ + + G DE S++ ++H L +++ +
Sbjct: 766 EARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRALTGEVEAHRGPVS 825
Query: 4918 ALATKAHKF--VEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREI 5091
L + PL +QVR + E+L+A + + Y + E+
Sbjct: 826 GLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEV 885
Query: 5092 DDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIG 5271
WI +KE S + V+++Q RF+ ++ ++ RV + N L+
Sbjct: 886 HACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESLDQEMNSLMG-RVLDVNHTVQELVE 944
Query: 5272 HGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHA 5451
GH + + +D LN W ++EL++ R + + A L+ + + +++ EK A
Sbjct: 945 GGHPSSDEVRSCQDHLNSRWNRIVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRRA 1004
Query: 5452 MPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRES 5631
+ + GAL + + A+ + A + +AA L + + +A +
Sbjct: 1005 VESA----PRAGGALQWRLSGLEAALQALEPRQAALLEEAALLAERFPA-QAARLHQGAE 1059
Query: 5632 EVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERP--KDVSG 5805
E+ W L A + L +F++ + L W+ + E P +
Sbjct: 1060 ELGAEWGALASAAQACGEAVAAAGRLQRFLHDLDAFLDWLVRAQEAAGGSEGPLPNSLEE 1119
Query: 5806 VELLMNNHQSLKAEIDAREENFNACISLGRDLL---NRKHYASSEIEKKLIKLTTERAEM 5976
+ L+ H +LK E+D REE++ ++ LL + +++ L L ++
Sbjct: 1120 ADALLARHAALKEEVDQREEDYARIVAASEALLAADGAELGPGLALDEWLPHLELGWHKL 1179
Query: 5977 MRRWEDRWEYLQLILEVYQ-FARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEA 6153
+ W+ R + L + +YQ F RD A L QE L E +E + +K+H
Sbjct: 1180 LGLWKARRKAL-VQAHIYQLFLRDLRQALVVLRNQEMALSGAELPGTVESVEEALKQHRD 1238
Query: 6154 F 6156
F
Sbjct: 1239 F 1239
Score = 146 bits (369), Expect = 6e-33
Identities = 140/683 (20%), Positives = 286/683 (41%), Gaps = 30/683 (4%)
Frame = +1
Query: 2239 DRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEARE 2418
+ +L + R++S ++ G + V+ +KKH+ + ++ +++ ++ + A++L E
Sbjct: 442 ESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEG-- 499
Query: 2419 HPDIRQ---RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLA 2589
+ DIR+ + D+ L+Q A L L R+ RL L+L K++ + + W++E L
Sbjct: 500 YYDIRRVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLL 559
Query: 2590 TLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKL 2769
+ G+ + E + + + LE D+ Q +V +N A + P I +R N +
Sbjct: 560 SRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQPCDPQV--ICNRVNHV 617
Query: 2770 NARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDAL--------- 2922
+ A+L++ ++R ELE + L + +E +W DK R+LE +
Sbjct: 618 HGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAA 677
Query: 2923 -----TNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKR 3087
+DLS +L + +++ +LG +A L ++A E A+
Sbjct: 678 GTAGGAHDLSSTARLLAQHKILQGELGGRRASL----QQALRCGEELVAAGGAVGPGADT 733
Query: 3088 IHQV------------WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVAS 3231
+H V W L + E +L EA L +F DLD WL R A+
Sbjct: 734 VHLVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAA 793
Query: 3232 EEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRA-MGDRVTQDQTDPQYMFLRQRLAG 3408
+ A + +L QH A+ E++ + +R + P + L+ R+
Sbjct: 794 GDFGHDEASSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRVVE 853
Query: 3409 LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN 3588
++ + E+ + R+ L L + + E+ + ++E +L +P SL+ E
Sbjct: 854 AEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEV 913
Query: 3589 QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
R + M++ ++ V +L + GH ++D++ +++ R E ++
Sbjct: 914 VQHRFESLDQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNRIVELVEQ 973
Query: 3769 VLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAAN 3948
+++ L ++ + + E+R + EK RA + R + + ++ L A
Sbjct: 974 RKEEMSAVLLVENHVLEVAEVRAQVREKR-RAVESAPRAGGALQWRL---SGLEAALQAL 1029
Query: 3949 KERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYV 4128
+ R L A L + P + EEL +W L + G+ + A R Q ++
Sbjct: 1030 EPRQAALLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRLQRFL 1089
Query: 4129 QSIADMKEWATQLENEMTREDQP 4197
+ +W + + + P
Sbjct: 1090 HDLDAFLDWLVRAQEAAGGSEGP 1112
Score = 109 bits (272), Expect = 1e-21
Identities = 198/1033 (19%), Positives = 377/1033 (36%), Gaps = 75/1033 (7%)
Frame = +1
Query: 2716 LNVEHPNSDDIL-------HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETV 2874
+N+E P+ I+ H +K+ A + + + LE +E + E +
Sbjct: 263 VNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDQVLEVGKIIERYEELAAELL 322
Query: 2875 TWIEDKTRVLEDSDALTNDLSGVMK----------LQRRLSMMERDLGAIQAKLDSLHKE 3024
WI +T L + N LSGV + L++ + E+ G ++ L S+ +
Sbjct: 323 AWIH-RTVGLISNQKFANSLSGVQQQLQAFTAYCTLEKPVKFQEK--GNLEVLLFSIQSK 379
Query: 3025 ADDIERER--PQEAQAIREDIKRIHQVWDILNKKVREHEAKL------DEAGDL--QRFL 3174
R P+E I + I + W L K E EA L E +L QRF
Sbjct: 380 LRACNRRLFVPREGCGIWD----IDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFD 435
Query: 3175 RDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRV 3354
+ ++WL QR V+ + L E + +H AI +I Y E + + + +
Sbjct: 436 HKVAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQAL 495
Query: 3355 TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQ 3534
+ QR + L++ W L + R+ L Q L LQ ++ + +
Sbjct: 496 AAEGYYDIRRVAAQRDSVLRQ-WALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEM 554
Query: 3535 ENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHK 3714
+ L + Q L +A++ L++H + A E++ A+ + Q I
Sbjct: 555 QAQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQPCD--PQVICN 612
Query: 3715 KARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI--EEKMIRAQDET---- 3876
+ ++ +E+A +L+ + SL L + +E W +E+++ A
Sbjct: 613 RVNHVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAG 672
Query: 3877 ----------YRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTID 4026
D + +H+ Q EL + L Q A+ G++ G +
Sbjct: 673 AAGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRASLQQ----ALRCGEELVAAGGAVG 728
Query: 4027 PQIEEL------------ATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLE 4170
P + + +W LE+ + ++L +A + + + +W
Sbjct: 729 PGADTVHLVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAY 788
Query: 4171 NEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAH 4350
D D + + +QH T ++ + + A
Sbjct: 789 RLAAAGDFGHDEASSR-RLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVAL 847
Query: 4351 RLAVQEQLQRLQAPLDD----RRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGE 4518
++ V E ++L A + + RR+ L A ++ +V +LWI E+ + + +
Sbjct: 848 QVRVVEA-EQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPD 906
Query: 4519 SLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQE 4698
SL D +Q + L E+++ + + + QEL++ GH + L S W
Sbjct: 907 SLDDVEVVQHRFESLDQEMNSLMGRVLDVNHTVQELVEGGHPSSDEVRSCQDHLNSRWNR 966
Query: 4699 LKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHER 4878
+ E V+ RK ++ + + E A + E+ + ++ +
Sbjct: 967 IVELVEQRKEEMSAVLLVENHVLEVAEVRAQVREKRR------------AVESAPRAGGA 1014
Query: 4879 LQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQI----EKL---YAGLQDXXXX 5037
LQ + ++AL + +EE + L E+ + A++ E+L + L
Sbjct: 1015 LQWRLSGLEAALQALEPRQAALLEEAALLAERFPAQAARLHQGAEELGAEWGALASAAQA 1074
Query: 5038 XXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQEN--GQDYEHVQMLQERFQQFARDT 5211
++D L W+ + AG E E L R +
Sbjct: 1075 CGEAVAAAGRLQRFLHDLDAFLDWLVRAQEAAGGSEGPLPNSLEEADALLARHAALKEEV 1134
Query: 5212 ENIGSE--RVANANDGCDTLIGHGHTDAPTIAL--WKDSLNEAWENLLELMDTRAQILEA 5379
+ + R+ A++ L G P +AL W L W LL L R + L
Sbjct: 1135 DQREEDYARIVAASEA--LLAADGAELGPGLALDEWLPHLELGWHKLLGLWKARRKALVQ 1192
Query: 5380 SRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQ 5556
+ + F D R L + + A+ +L SV ++H+++L + + +Q Q
Sbjct: 1193 AHIYQLFLRDLRQALVVLRNQEMALSGAELPGTVESVEEALKQHRDFLTTM-ELSQQKMQ 1251
Query: 5557 IERDAAE--LRDG 5589
+ AAE LR G
Sbjct: 1252 VAVQAAEGLLRQG 1264
Score = 90.1 bits (222), Expect = 7e-16
Identities = 147/816 (18%), Positives = 315/816 (38%), Gaps = 39/816 (4%)
Frame = +1
Query: 1909 VAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQD 2088
VA E + E ++++S + G ++ V + KH+ E D+ Y +R+ + Q
Sbjct: 438 VAMRESWLNENQRLVSQDNFGYELPAVEAAMKKHEAIE---ADIAAYEERVQGVAELAQA 494
Query: 2089 ESIPGSDNIPPRLAEIRDYINK----LKELSASRKERLAGGVEYYQFFTDADDVDRYLYD 2256
+ G +I R+A RD + + L L +R+ RL + + F + + ++ +
Sbjct: 495 LAAEGYYDIR-RVAAQRDSVLRQWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEE 553
Query: 2257 TLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQ 2436
+ S + G+ LL+KH + ++ + ++ L+A A Q + I
Sbjct: 554 MQAQLLSRECGQHLVEADDLLQKHGLLEGDIAAQSERVEALNAAALRFSQPC-DPQVICN 612
Query: 2437 RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPG---- 2604
R++ AEL+ + R+ L + SL+ L + + ESW +K +LL G
Sbjct: 613 RVNHVHGCLAELQEQAARRRAELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAG 672
Query: 2605 -----------RDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLL---NVEHPNSD 2742
D+ + + L+ ++ + A + +L+ P +D
Sbjct: 673 AAGAAGTAGGAHDLSSTARLLAQHKILQGELGGRRASLQQALRCGEELVAAGGAVGPGAD 732
Query: 2743 DI-----LHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
+ R RW +L + ++ L+ A L F D + W+ D R+
Sbjct: 733 TVHLVGLAERAASARRRWQRLEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAA 792
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKR 3087
D +D + +L R+ + ++ A + + L ++ + + ++
Sbjct: 793 AGD-FGHDEASSRRLARQHRALTGEVEAHRGPVSGLRRQLATLGGASGAGPLVVALQVRV 851
Query: 3088 IH--QVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEA 3261
+ Q++ + + L +A + R ++ + W+ ++ + S P SL +
Sbjct: 852 VEAEQLFAEVTEVAALRRQWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDV 911
Query: 3262 EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRM 3441
E + ++ ++ +E++ + + + P +R L W + +
Sbjct: 912 EVVQHRFESLDQEMNSLMGRVLDVNHTVQELVEGG-HPSSDEVRSCQDHLNSRWNRIVEL 970
Query: 3442 WDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITT 3621
+ R+ +S L ++ + + AEV +E A + P++ + +L + +
Sbjct: 971 VEQRKEEMSAVLLVENHVLEV--AEVRAQVREKRRAVESAPRAGGALQWRLSGLEAALQA 1028
Query: 3622 MDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSL 3801
++ + L + A ++H+ A + GA AQ + + A L
Sbjct: 1029 LEPRQAALLEEAAL---LAERFPAQAARLHQGAEELGAEWGALASAAQACGEAVAAAGRL 1085
Query: 3802 QQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKH-- 3975
Q+FL D D +W+ +RAQ+ + + A + AA KE +DQ +
Sbjct: 1086 QRFLHDLDAFLDWL----VRAQEAAGGSEGPLPNSLEEADALLARHAALKEEVDQREEDY 1141
Query: 3976 -------AAINLGDDKPEYHG-TIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQ 4131
A+ D G +D + L W +L + + + L A+ QL+++
Sbjct: 1142 ARIVAASEALLAADGAELGPGLALDEWLPHLELGWHKLLGLWKARRKALVQAHIYQLFLR 1201
Query: 4132 SIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQH 4239
+ E ++ + PG + +V A+ KQH
Sbjct: 1202 DLRQALVVLRNQEMALSGAELPGTVESVEEAL-KQH 1236
Score = 72.8 bits (177), Expect = 1e-10
Identities = 111/566 (19%), Positives = 214/566 (37%), Gaps = 36/566 (6%)
Frame = +1
Query: 4669 IQELRSAWQELKEAVKDR----KGDLGESEK----AHQFLYDCGEAEAWMSEQELYMMQD 4824
I ++ AW EL++A +R + +L EK A +F + E+W++E + + QD
Sbjct: 396 IWDIDKAWGELEKAEHEREAALRAELIRQEKLELLAQRFDHKVAMRESWLNENQRLVSQD 455
Query: 4825 ERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEK 5004
G + + + +KKHE +++DI + + ++ +A A E ++ ++ + +
Sbjct: 456 NFGYELPAVEAAMKKHEAIEADIAAYEERVQGVAELAQALAAEGYYDIRRVAAQRDSVLR 515
Query: 5005 LYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQE 5184
+A L + +E+ ++ W+ + + S+E GQ L +
Sbjct: 516 QWALLTGLVGARRTRLEQNLALQKVFQEMVYMVDWMEEMQAQLLSRECGQHLVEADDLLQ 575
Query: 5185 RFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRA 5364
+ D SERV N L D I + ++ L E R
Sbjct: 576 KHGLLEGDIA-AQSERVEALN--AAALRFSQPCDPQVICNRVNHVHGCLAELQEQAARRR 632
Query: 5365 QILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLG----------------RDSSSVGAL 5496
LEASR L + + S +K + G D SS L
Sbjct: 633 AELEASRSLWALLQELEEAESWARDKERLLEAAGGGGAAGAAGAAGTAGGAHDLSSTARL 692
Query: 5497 SRKHQNYLKDIAAIGEQVAQIERDAAEL--RDGYAGDKA-----LDIGSRESEVVKAWRH 5655
+H+ ++ + Q R EL G G A + + R + + W+
Sbjct: 693 LAQHKILQGELGGRRASLQQALRCGEELVAAGGAVGPGADTVHLVGLAERAASARRRWQR 752
Query: 5656 LRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQS 5835
L R RL + L +F + LL W+ + R + + D + L H++
Sbjct: 753 LEEAAARRERRLQEARALHQFGADLDGLLDWLRDAYRLAAAGDFGHDEASSRRLARQHRA 812
Query: 5836 LKAEIDAREENFNACISLGRDLLNRKHYASS-----EIEKKLIKLTTERAEMMRRWEDRW 6000
L E++A L R L + + ++ ++++ AE+ R
Sbjct: 813 LTGEVEAHR---GPVSGLRRQLATLGGASGAGPLVVALQVRVVEAEQLFAEVTEVAALRR 869
Query: 6001 EYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQE 6180
++L+ L VY+ + E W+ +E +L+S +L++ + + E+ ++ +
Sbjct: 870 QWLRDALAVYRMFGEVHACELWIGEKEQWLLSMRVPDSLDDVEVVQHRFESLDQEMNSLM 929
Query: 6181 ERFLALEKLTTFELKETQHREEETAK 6258
R L + T EL E H + +
Sbjct: 930 GRVLDVNH-TVQELVEGGHPSSDEVR 954
>gi|338330|gb|AAA63259.1| muscle beta spectrin
Length = 1274
Score = 924 bits (2388), Expect = 0.0
Identities = 506/1253 (40%), Positives = 740/1253 (58%), Gaps = 61/1253 (4%)
Frame = +1
Query: 3142 LDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAED 3321
L E LQ FL+DLD FQAWL+ TQ+ VASE+ P+SL EAEQLL QHA I++EIDG+ +
Sbjct: 3 LGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQDS 62
Query: 3322 YKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRD 3501
Y++++ G++V Q QTDP+Y+ L QRL GL GW+ L RMW++R H L+Q L Q F +D
Sbjct: 63 YQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWDALGRMWESRSHTLAQCLGFQEFQKD 122
Query: 3502 AKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQ 3681
AKQAE +LS QE LA + P SLE AE +++ +DF+ +M+ N +K+ + G++L
Sbjct: 123 AKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRDKVLSPVDSGNKLVA 182
Query: 3682 DGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIR 3861
+G+ +DKI +K + I++R N EKAQE L+D L LQ FL +C EL WI +K++
Sbjct: 183 EGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQNCQELTLWINDKLLT 242
Query: 3862 AQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEE 4041
+QD +Y +A+ + +K+++HQAF +ELA+++ L+ + L D+KP++ + ++E
Sbjct: 243 SQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEA 302
Query: 4042 LATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNV 4221
L WDEL+ TT+EK Q L A L +Q+ AD+ +W + +E+++ +D DLT+VN
Sbjct: 303 LHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTSVNR 362
Query: 4222 AMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDD 4401
+ K +E ++ + + + P E L+++++ L PL
Sbjct: 363 MLAKLKRVEDQVNVRKEELGELFAQV-------PSMGEEGGDADLSIEKRFLDLLEPLGR 415
Query: 4402 RRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDN 4581
R+K LE +A Q RD++DE LW+ ERL LA++ + G +L K Q L NEI
Sbjct: 416 RKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQNEILG 475
Query: 4582 HEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQF 4761
H P + + GQ+L++ + E+++ L+S+W L+EA R L ++ +A Q+
Sbjct: 476 HTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAGRLQRLRDANEAQQY 535
Query: 4762 LYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHK 4941
D EAEAW+ EQELY++ DE KDE +K+H R Q ++ + I+ LA++A
Sbjct: 536 YLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVEDYGRNIKQLASRAQG 595
Query: 4942 FVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADK 5121
+ P EQI Q Q++K YAGL+D + L RE DDL QWI++K
Sbjct: 596 LLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQLKRETDDLEQWISEK 655
Query: 5122 EVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIA 5301
E+VA S E GQD++HV +L+++F+ FAR+T IG ERV N N + LI GH++A TIA
Sbjct: 656 ELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIERLIDAGHSEAATIA 715
Query: 5302 LWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSS 5481
WKD LNE W +LLEL+DTR Q+L AS LH++++ + L I EK +P+D+G D+S
Sbjct: 716 EWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDEKHRELPEDVGLDAS 775
Query: 5482 SVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLR 5661
+ + R H + +D+ +G QV Q + A L+ YAG+KA I ++E EV AW+ L
Sbjct: 776 TAESFHRVHTAFERDVHLLGVQVQQFQDVATRLQTAYAGEKAEAIQNKEQEVSAAWQALL 835
Query: 5662 GLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLK 5841
C R ++L+DT+D F+F +M RDLL WM+ + R++ +QERP+DVS VELLM HQ +
Sbjct: 836 DACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDVSSVELLMKYHQGIN 895
Query: 5842 AEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLIL 6021
AEI+ R +NF+AC+ LG LL R+H AS EI +KL ++ + R EM +WE RWE L+++L
Sbjct: 896 AEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMNEKWEARWERLRMLL 955
Query: 6022 EVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALE 6201
EV QF+RDA+VAE+WL AQEPYL S ++G ++ KLIK+HEAFEKS + ERF ALE
Sbjct: 956 EVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFEKSTASWAERFAALE 1015
Query: 6202 KLTTFELKE------------TQHREEETAKRRGPAHIGSPSRSTPAAETSF-------- 6321
K TT ELKE Q E ETA +H + R++P E
Sbjct: 1016 KPTTLELKERQIAERPAEETGPQEEEGETAGEAPVSHHAATERTSPGEEEGTWPQNLQQP 1075
Query: 6322 ---GAQDDGAK------------------------------------QGEAFEGTLIRKH 6384
G DG K Q EG L RKH
Sbjct: 1076 PPPGQHKDGQKSTGDERPTTEPLFKVLDTPLSEGDEPATLPAPRDHGQSVQMEGYLGRKH 1135
Query: 6385 TYESLDRKAANRSWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDY 6558
E ++KA+NRSW LY VLR +EL+FYKD K+ + HGE P+AL +A++Y
Sbjct: 1136 DLEGPNKKASNRSWNNLYCVLRNSELTFYKDAKNLALGMPYHGEEPLALRHAICEIAANY 1195
Query: 6559 QKKKNVLSLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLP 6717
+KKK+V LRL G+E+LF EE+M WL + A ++Q ++Q+LP
Sbjct: 1196 KKKKHVFKLRLSNGSEWLFHGKDEEEMLSWLQGVSTAINESQSIRV-KAQSLP 1247
Score = 223 bits (569), Expect = 4e-56
Identities = 195/915 (21%), Positives = 396/915 (42%), Gaps = 19/915 (2%)
Frame = +1
Query: 925 QLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFT-LQSAMRANNQRPF 1101
Q L + F+ + + + L+ +PP E E + F +M N +
Sbjct: 112 QCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRDKVL 171
Query: 1102 VP--------REGKLIADINRAWQSLEKAEHER--ELVLKEELIRQEKLEQLAARFNRKA 1251
P EG L +D + L + H + E + ++ ++ LE F +
Sbjct: 172 SPVDSGNKLVAEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLE--LQNFLQNC 229
Query: 1252 EMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXX 1431
+ W+ + + L SQD ++ ++ KH+A ++ ++E
Sbjct: 230 QELTLWIND-KLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDE 288
Query: 1432 NYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRL 1611
A ++++ E + + L + + ++ +L
Sbjct: 289 KPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQL 348
Query: 1612 LSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPG 1791
S+D G L V +L K +E +N+ E + AQ P
Sbjct: 349 RSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQV------------------PS 390
Query: 1792 TIDERSDV---LQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSST 1962
+E D ++KR+ +LL+ RK++LE ++ Q D+ + ++E+ + S
Sbjct: 391 MGEEGGDADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSA 450
Query: 1963 DTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRD 2142
D G ++ TV + K++ +N + ++ + G++L + + ++ RL ++
Sbjct: 451 DYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQS 510
Query: 2143 YINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLK 2322
++L+E +A R +RL E Q++ DAD+ + ++ + + S+++ KDE ++LK
Sbjct: 511 SWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLK 570
Query: 2323 KHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQ--RLDTTL-KQKAELENLSQLR 2493
+H ++++ ++IK L ++A+ L HP+ Q RL + K A L+++++ R
Sbjct: 571 RHLRQQRAVEDYGRNIKQLASRAQGLLSAG--HPEGEQIIRLQGQVDKHYAGLKDVAEER 628
Query: 2494 KQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRF-DTLEQDMKN 2670
K++L + L++L + D +E WI EK + ++ G+D + V +++ +F D +
Sbjct: 629 KRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAI 688
Query: 2671 QEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETF 2850
+ +V NVN +L++ H + I ++ LN WA L +++D + L ++ L +
Sbjct: 689 GQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRY 748
Query: 2851 RIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEAD 3030
E + I++K R L + L D S R + ERD+ + ++ A
Sbjct: 749 FYTGAEILGLIDEKHRELPEDVGL--DASTAESFHRVHTAFERDVHLLGVQVQQFQDVAT 806
Query: 3031 DIERE-RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLT 3207
++ ++A+AI+ + + W L +L + D RF +W+
Sbjct: 807 RLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWME 866
Query: 3208 ATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMF 3387
+ RQ+ ++E P+ ++ E L+ H I EI+ ++++ +G+ + Q Q
Sbjct: 867 SIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEE- 925
Query: 3388 LRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQ 3567
+R++L + +E+ W+ R L L + F RDA AE L QE YLA D
Sbjct: 926 IREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGH 985
Query: 3568 SLEQAENQLKRHQDF 3612
+++ E +KRH+ F
Sbjct: 986 TVDSVEKLIKRHEAF 1000
Score = 164 bits (415), Expect = 3e-38
Identities = 194/1025 (18%), Positives = 402/1025 (38%), Gaps = 17/1025 (1%)
Frame = +1
Query: 2188 LAGGVEYYQ-FFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQ 2364
L G V Q F D DD +L T + ++SED+ + + LL++H + DE+
Sbjct: 2 LLGEVSQLQAFLQDLDDFQAWLSITQKAVASEDMPESLPEAEQLLQQHAGIKDEIDGHQD 61
Query: 2365 HIKVLHAKAESLPQEAR--EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYS 2538
+ + E + Q E+ + QRL+ L + + R L L +
Sbjct: 62 SYQRVKESGEKVIQGQTDPEYLLLGQRLEGLDTGWDALGRMWESRSHTLAQCLGFQEFQK 121
Query: 2539 DADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLL 2718
DA E+ + + LA L P +E E +F+ M+N KV + D +L+
Sbjct: 122 DAKQAEAILSNQEYTLAHLEPPDSLEAAEAGIRKFEDFLGSMENNRDKVLSPVDSGNKLV 181
Query: 2719 NVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTR 2898
+ SD I + + R + + + L L+ F +CQE WI DK
Sbjct: 182 AEGNLYSDKIKEKVQLIEDRHRKNNEKAQEASVLLRDNLELQNFLQNCQELTLWINDK-- 239
Query: 2899 VLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIRED 3078
+L D ++ + + +L + + L+++ E + E+PQ + +
Sbjct: 240 LLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQK 299
Query: 3079 IKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAE 3258
++ +H++WD L +E L A L+ W++A + Q+ S++ + L
Sbjct: 300 LEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQLRSDDPGKDLTS 359
Query: 3259 AEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQR 3438
++L + + ++++ E+ ++ A + ++ D + + +R L L+
Sbjct: 360 VNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDAD-LSIEKRFLDL------LEP 412
Query: 3439 MWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFIT 3618
+ ++ L S LQ+ RD + + + ++ D +L+ + +K++Q
Sbjct: 413 LGRRKKQLESSRAKLQI-SRDLEDETLWVEERLPLAQSADYGTNLQTVQLFMKKNQTLQN 471
Query: 3619 TMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALS 3798
+ + ++ V G QL + + ++ ++ RE A L++L+DA
Sbjct: 472 EILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAGRLQRLRDANE 531
Query: 3799 LQQFLSDCDELREWI-EEKMIRAQDETYRD---AKTITSKFVRHQAFQSELAANKERLDQ 3966
QQ+ D DE WI E+++ DE +D A + + +R Q + N ++L
Sbjct: 532 AQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVEDYGRNIKQLAS 591
Query: 3967 LKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADM 4146
++ G + E + Q+++ + L+ EE+ +KL + + D+
Sbjct: 592 RAQGLLSAGHPEGEQIIRLQGQVDK---HYAGLKDVAEERKRKLENMYHLFQLKRETDDL 648
Query: 4147 KEWATQLENEMTREDQPGDLTTVNVAMQK--QHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
++W ++ E + + D V + K ET I + + +D
Sbjct: 649 EQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQ-ERVDNVNAFIERLIDAG 707
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERK---KAAFQFGRD----VDDEKLWIS 4479
E I + + E L +D R + L F G + +D++ +
Sbjct: 708 HSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDEKHRELP 767
Query: 4480 ERLVLAKAQNLGESLPDCH-RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPA 4656
E + L + ES H ++++ LL ++ + ++ + G A
Sbjct: 768 EDVGL--DASTAESFHRVHTAFERDVHLLGVQVQQFQDVATRL-----QTAYAGE-KAEA 819
Query: 4657 FEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGK 4836
+ K QE+ +AWQ L +A R+ L ++ +F + +WM + ER +
Sbjct: 820 IQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPR 879
Query: 4837 DEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAG 5016
D S + +K H+ + ++I+ + A ++ + +E+I+ + Q+
Sbjct: 880 DVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKE 939
Query: 5017 LQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQ 5196
+ + R+ W+ +E S + G + V+ L +R +
Sbjct: 940 MNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEA 999
Query: 5197 FARDT 5211
F + T
Sbjct: 1000 FEKST 1004
Score = 159 bits (401), Expect = 1e-36
Identities = 191/993 (19%), Positives = 396/993 (39%), Gaps = 15/993 (1%)
Frame = +1
Query: 1615 SEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGT 1794
SED+ L + E LLQ+HA ++ +I + QR + G E
Sbjct: 32 SEDMPESLPEAEQLLQQHAGIKDEI-------DGHQDSYQRVKESGEKVIQGQTDPEYLL 84
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
+ +R + L + L + R L +F D + E + QE L+ +
Sbjct: 85 LGQRLEGLDTGWDALGRMWESRSHTLAQCLGFQEFQKDAKQAEAILSNQEYTLAHLEPPD 144
Query: 1975 DIVTVSHLLAKHKNAENNL-RDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYIN 2151
+ + K ++ ++ + +K L +D SG +L E SD I ++ I D
Sbjct: 145 SLEAAEAGIRKFEDFLGSMENNRDKVLSPVD-SGNKLVAEGNLYSDKIKEKVQLIEDRHR 203
Query: 2152 KLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG-TVQLLLKKH 2328
K E + L +E F + ++ ++ D ++++S+DV DE + KH
Sbjct: 204 KNNEKAQEASVLLRDNLELQNFLQNCQELTLWIND--KLLTSQDVSYDEARNLHNKWLKH 261
Query: 2329 DDVHDELQNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRL 2505
EL + + ++ + A+ + L E + + Q+L+ + EL+ ++ + Q L
Sbjct: 262 QAFVAELASHEGWLENIDAEGKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHL 321
Query: 2506 IDALSL-YKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAK 2682
A S +L + AD + WI L + PG+D+ V M + +E + +
Sbjct: 322 SAARSSDLRLQTHAD-LNKWISAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQV---NVR 377
Query: 2683 VTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDC 2862
+ +L Q+ ++ D L + R+ L + + +++ +LE + D
Sbjct: 378 KEELGELFAQVPSMGEEGGDADL----SIEKRFLDLLEPLGRRKKQLESSRAKLQISRDL 433
Query: 2863 QETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIER 3042
++ W+E++ + + +D TN L V ++ ++ ++ +++ + + +
Sbjct: 434 EDETLWVEERLPLAQSADYGTN-LQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVE 492
Query: 3043 ERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQ 3222
+ Q + E + + WD L + +L +A + Q++ D D +AW+ +
Sbjct: 493 AAEIDCQDLEERLGHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELY 552
Query: 3223 VASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKM--RAMGDRVTQDQTDPQYMFLR- 3393
V S+E P+ A +L +H + ++ Y + K++ RA G Q + L+
Sbjct: 553 VISDEIPKDEEGAIVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQG 612
Query: 3394 ---QRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIP 3564
+ AGL++ EE +R +N HL R+ E +S++E + ++
Sbjct: 613 QVDKHYAGLKDVAEERKRKLENMYHLF-------QLKRETDDLEQWISEKELVASSPEMG 665
Query: 3565 QSLEQAENQLKRHQDFITTMDA-NDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERR 3741
Q + + +DF A E++ V F ++L GH A I + ++E
Sbjct: 666 QDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMW 725
Query: 3742 GANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQ 3921
E ++ L + L ++ E+ I+EK ++ DA T S H
Sbjct: 726 ADLLELIDTRMQLLAASYDLHRYFYTGAEILGLIDEKHRELPEDVGLDASTAESFHRVHT 785
Query: 3922 AFQSELAANKERLDQLKHAAINL----GDDKPEYHGTIDPQIEELATQWDELEKTTEEKG 4089
AF+ ++ ++ Q + A L +K E I + +E++ W L +
Sbjct: 786 AFERDVHLLGVQVQQFQDVATRLQTAYAGEKAE---AIQNKEQEVSAAWQALLDACAGRR 842
Query: 4090 QKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKA 4269
+L D + + D+ W + ++ +++P D+++V + M+ I E+ ++
Sbjct: 843 TQLVDTADKFRFFSMARDLLSWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRS 902
Query: 4270 QHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGR 4449
++ E I+ V + + + + R + L QF R
Sbjct: 903 KNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSR 962
Query: 4450 DVDDEKLWISERLVLAKAQNLGESLPDCHRLQK 4548
D + W+ + + + G ++ +L K
Sbjct: 963 DASVAEAWLIAQEPYLASGDFGHTVDSVEKLIK 995
Score = 141 bits (355), Expect = 3e-31
Identities = 180/869 (20%), Positives = 354/869 (40%), Gaps = 38/869 (4%)
Frame = +1
Query: 832 KVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENN------------------ 957
KV++ + +K++ S + E K+QL+ +RH +NN
Sbjct: 169 KVLSPVDSGNKLVAEGNLYSDKIKE----KVQLIEDRHRKNNEKAQEASVLLRDNLELQN 224
Query: 958 -LEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQS--AMRANNQRPF--VPREGKL 1122
L+ Q ND + +DE L Q+ A A+++ + EGK
Sbjct: 225 FLQNCQELTLWINDKLLTSQDVSYDEARNLHNKWLKHQAFVAELASHEGWLENIDAEGKQ 284
Query: 1123 IADINRAWQSLEKAEHERELVLKEEL--IRQEKLEQLAA------RFNRKAEMRETWLTE 1278
+ D + +L + E L +EL +EK + L+A R A++ + W++
Sbjct: 285 LMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNK-WISA 343
Query: 1279 NQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKIN 1458
+ + D+ G DL+SV K + +E + +E I
Sbjct: 344 MEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLSIE 403
Query: 1459 ERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRL---LSEDLG 1629
+R ++ + R +L++S ++ ++ RL S D G
Sbjct: 404 KRFLDLLEPLGRRKKQLESSRAKLQISRDLED----------ETLWVEERLPLAQSADYG 453
Query: 1630 AHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERS 1809
+L V+ ++K+ L+++I RV + + + Q+ ++ ++ER
Sbjct: 454 TNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEA--------AEIDCQDLEERL 505
Query: 1810 DVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTV 1989
LQ + L + AA R +RL D Q++ D E E I EQE + S + +D
Sbjct: 506 GHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGA 565
Query: 1990 SHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELS 2169
+L +H + + D + + +L + L P + I ++ + LK+++
Sbjct: 566 IVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVA 625
Query: 2170 ASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDEL 2349
RK +L +Q + DD+++++ + V SS ++G+D V LL K D E
Sbjct: 626 EERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARET 685
Query: 2350 QNFDQH-IKVLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSL 2523
Q + ++A E L E I + D + A+L L R Q L + L
Sbjct: 686 GAIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDL 745
Query: 2524 YKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDL 2703
++ + + IDEK + L V G D E E+D+ +V D+
Sbjct: 746 HRYFYTGAEILGLIDEKHRELPEDV-GLDASTAESFHRVHTAFERDVHLLGVQVQQFQDV 804
Query: 2704 ARQLLNV-EHPNSDDILHRQNKLNARWAQLRDMVDQKRNEL-ERAHRLETFRIDCQETVT 2877
A +L ++ I +++ +++A W L D +R +L + A + F + ++ ++
Sbjct: 805 ATRLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSM-ARDLLS 863
Query: 2878 WIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQE 3057
W+E R +E + D+S V L + + ++ + + + + + + Q
Sbjct: 864 WMESIIRQIETQER-PRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQA 922
Query: 3058 AQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEE 3237
++ IRE ++++ +N+K +L ++ +F RD +AWL A + +AS +
Sbjct: 923 SEEIREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGD 982
Query: 3238 EPQSLAEAEQLLNQHAAIREEIDGYAEDY 3324
++ E+L+ +H A + +AE +
Sbjct: 983 FGHTVDSVEKLIKRHEAFEKSTASWAERF 1011
>gi|48136657|ref|XP_396777.1| similar to ENSANGP00000017034 [Apis
mellifera]
Length = 3684
Score = 904 bits (2337), Expect = 0.0
Identities = 589/2069 (28%), Positives = 1014/2069 (48%), Gaps = 93/2069 (4%)
Frame = +1
Query: 337 HVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITF---EDADNHETRSAKEALLLWC 507
+V LE++G+ DIVDGN RL LGLIWTIILRFQIQ+I E+ D+ E +SAK+ALLLWC
Sbjct: 17 YVRLESIGAEDIVDGNPRLILGLIWTIILRFQIQEIEIDVDEENDSSEKKSAKDALLLWC 76
Query: 508 QMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAEN 687
Q KT GYP VN+++F+ SWR GL FNALIH HRPDLV++ LQ++ + NL AFD A +
Sbjct: 77 QRKTNGYPGVNIQDFTGSWRSGLGFNALIHAHRPDLVNWSELQQNKNIDNLNYAFDVANS 136
Query: 688 QLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKM 867
+LG+ + LDAEDV+ +PDEKSIITYV +YYH F ++K + GKRI ++ ++M+ DKM
Sbjct: 137 ELGIPRLLDAEDVDTARPDEKSIITYVASYYHTFARMKNEIKSGKRIANIVGQMMDADKM 196
Query: 868 INRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELE 1047
YE L++DLLEWI KI +L R+F N+LEG+QR+L F YRT EKPPK+ E+ E+E
Sbjct: 197 KIHYEKLTTDLLEWIKMKIGVLENRNFPNSLEGIQRELLAFKQYRTVEKPPKYKERSEIE 256
Query: 1048 VLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQL 1227
L F + + +++ NQ F P+EG+LI DI R W LE+AEH RE+ L+ EL+RQE+LEQL
Sbjct: 257 ALYFHINTQLKSLNQPAFTPQEGQLIHDIERNWVELERAEHRREVALRTELLRQERLEQL 316
Query: 1228 AARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXX 1407
+F RK+ +RE +L E ++++ +G++L+ V+A KKHEAI DI A EER
Sbjct: 317 NYKFERKSVLREGYLKEMIQVLTDPRYGSNLAQVDATVKKHEAISADILAREERFHDLTN 376
Query: 1408 XXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXX 1587
NYH ++ R++ V + L ++ +
Sbjct: 377 MSEELVRENYHGLERVRIREQEVLQRWKELLTLLDHHKSNLVALSSLMSLMREIDTTLAS 436
Query: 1588 XXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQA-QRFRNPDGPDG 1764
++ S D+G HL+ VEDLLQKH+L E + +GE QA Q P
Sbjct: 437 IQELQLNFQSTDVGPHLLGVEDLLQKHSLQELQVTALGETQRRLGRQAAQHLAQPQSK-- 494
Query: 1765 SGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQE 1944
E + ++ ++L + Y +L++ + ERK RLED + F D + E + E++
Sbjct: 495 ------EVPLLQQKLEMLNRAYDDLVEYSKERKARLEDARNFFHFLQDHEDEESWLIEKQ 548
Query: 1945 QVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPR 2124
++ + + +D+ V L KHK ++ ++ ++L +G++L ++ P + I R
Sbjct: 549 RICKAGISAKDLRAVISLQQKHKALQDEMKVRRPKSEQLCDAGRKLIADNHPSALEIQNR 608
Query: 2125 LAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGT 2304
+ ++++ L+EL+A RK++L E +QF+ DA++ D ++ + + +++SED G DE +
Sbjct: 609 IDSLQEHWKVLEELAALRKKQLDDAAEAFQFYADANEADSWMNEKMALVASEDYGVDEPS 668
Query: 2305 VQLLLKKHDDVHDELQNFDQHIKVLHAKAESL-------------PQEAREHPDIRQRLD 2445
Q LL++H D+ EL + ++ L+ +AE L P+ E +
Sbjct: 669 AQALLQRHKDLEGELNAYKGDVQSLNMQAEKLIKSGISTLELSADPEPVAELEQEEWSKE 728
Query: 2446 TTLKQKAE--------LENLSQLRKQRLIDALSLYKLYSDA--------------DSVES 2559
L + E LE + L + + SLY + +
Sbjct: 729 IRLVPQDEWVDEIVERLEPRTVLEGRLVPQVKSLYPFSGQGMHMVKGEVMFLLNKTNPDW 788
Query: 2560 WIDEKGKLLATLVPGRDIEEVE--IMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHP 2733
W K VP + E+E I+ + E+ Q K T + +QL+ V
Sbjct: 789 WSVRKADGTDGFVPANYVRELEPKIIHVQVRRPEKVRVTQRVKKTK---MVKQLVPVRRV 845
Query: 2734 NS----------------DDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQ 2865
S D + RQ K+N +++L+++ ++ LE A RL F +C
Sbjct: 846 KSIKSTVKPVKRKIATDGDSVEKRQKKINETYSELQELALRRHALLEDAIRLYGFYRECD 905
Query: 2866 ETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERE 3045
+ WI+DK ++L D N + K ++ L+ DL A +++++ D+ R+
Sbjct: 906 DFEKWIKDKEKMLRIDDPRDNVETAKRKYEKFLT----DLSASGKRVEAIDAAVDEFVRQ 961
Query: 3046 RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV 3225
+ ++ + IHQ+WD LN + E L+ A ++ F R D W+ Q+
Sbjct: 962 GHSQLDKVKARQRHIHQLWDHLNWLKTQKEKSLEGASSVELFNRTCDEAHDWMLEKITQL 1021
Query: 3226 ASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLA 3405
+ E L + L +H + E+ E +K+ + + V + + R
Sbjct: 1022 DTAELGPDLKTVQALQRRHQHLERELAPVEEKVRKVNLLANSVKSSYPH-ELNNVNARQN 1080
Query: 3406 GLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAE 3585
++E W ++Q R+ L + Q+F+ +K + + ++ + + AE
Sbjct: 1081 EIKELWNQVQTKAKERRSRLEDAVGQQIFMNSSKNLINWAVDIQETMKVEEPVRDVATAE 1140
Query: 3586 NQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQ 3765
K H + + +++ R V G+QL + D + +D+ G +
Sbjct: 1141 QLRKHHIELGEDIRTREDEFREVEELGNQLLRRNPTLVDV----SERLDKLHGLYQAVTS 1196
Query: 3766 EVLKK---LKDALSLQQFLSDCDELREWIE--EKMIRAQD--ETYRDAKTITSKFVRHQA 3924
+ + K L+ L LQQF + D++ E + D E+ D + + + H+
Sbjct: 1197 DWIAKEAWLQQCLDLQQFNREADQIEATTSSHEAFLEFTDLGESLDDVEALLKQ---HEK 1253
Query: 3925 FQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFD 4104
F++ L A +RL A L I+ + ++ + ++++ + + L
Sbjct: 1254 FENTLHAQDDRLKAFSDTADKLIAQNHYDKDYINDRRNQVLARRNQVKDAAQRRRAALKA 1313
Query: 4105 ANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDX 4284
+ Q + + D+++W + + ++ DL + +QK E E+ +
Sbjct: 1314 SEHYQQFSAEVDDLRDWLGD-KMKTASDESYRDLNNLERKLQKHEAFERELRANEGQLRA 1372
Query: 4285 XXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDE 4464
+++ + +Q +L ++ + L + + R ++D
Sbjct: 1373 VNKAGKALISEENYRSDDVGETLKELNDQWNQLVDLSLEKGRRLRQAACQHGYNRTMEDA 1432
Query: 4465 KLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHA 4644
+L + E +++ +G L C L K Q L +++ E ++ + G+E+ EGH
Sbjct: 1433 RLKLEEIENCLQSKQVGVDLRSCKELLKKHQTLESDMCQWEQKVDDLVVMGEEMAHEGHF 1492
Query: 4645 NGPAFEK-------KIQEL----RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
+ + KI+EL AW+ L+E +R DL S KA +F ++ GE E+W
Sbjct: 1493 DALGLLEEYWVSRGKIRELCDVLDEAWRGLQEKAAERNKDLELSLKAQEFFFEAGEVESW 1552
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
++E+ + + G+D + + KH+ ++ ++D + + + A + K P ++
Sbjct: 1553 LNEKNDVLSSTDYGRDRDAATKLLTKHKAVELELDTYNGIVTEMGHTAAIMINAKHPDSK 1612
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENG 5151
I +Q I + LQ + E +L QWI ++E A S++ G
Sbjct: 1613 AIANKQQAIAQQMRALQRLATVRQQRLMESMYRHEYFLESRELEQWIKEQEQAAASEDYG 1672
Query: 5152 QDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGH---------------GHTD 5286
QDYEH+ +LQ +F F E GSER + LI + G D
Sbjct: 1673 QDYEHLLILQAKFNDFKHRIE-AGSERFNQCEELARKLIANESPYIQDIEKRQEQLGQDD 1731
Query: 5287 APTIALWK---DSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP 5457
+ + D + E+W++LL L+ R Q L+A+ +H+F+ D + LSRI EK A+P
Sbjct: 1732 DDPVRQVQRQHDLIKESWKHLLGLIRNREQRLQAAGEIHRFHRDVAEALSRIQEKEAALP 1791
Query: 5458 DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEV 5637
+DLGRD +SV AL R+H+ + D+ A+ Q+ + DA+ L+ Y G+ A+ I ++ V
Sbjct: 1792 EDLGRDLNSVLALIRRHEGFENDLVALEAQLQVLVEDASRLQAHYPGNNAVHIDQQQQIV 1851
Query: 5638 VKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELL 5817
V W L+ R +L + DL +F+ VRDL+ W ++ M+++++ +D + ++L
Sbjct: 1852 VAHWEELKERSALRRDQLQASCDLQRFLTQVRDLMNWAAGLRAAMSTEDKVRDAASAQIL 1911
Query: 5818 MNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDR 5997
H++LK EI+ARE++F++ + LG ++ HYA+ E+E+K +L ER ++ W+ +
Sbjct: 1912 KAEHEALKGEIEAREDSFSSVLDLGEAMVQTGHYAALEVEEKCNQLLDERQKLHSAWQQK 1971
Query: 5998 WEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQ 6177
+L +++++ F RDA ++ QE L +G ++EE +KKH FEK Q
Sbjct: 1972 KVHLDQLIDLHFFLRDAKQLDNLSTTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQ 2031
Query: 6178 EERFLALEKLTTFELKETQHREEETAKRR 6264
EE+ AL++ +L H + T RR
Sbjct: 2032 EEKLTALQEHGD-KLLAQNHFDSPTIARR 2059
Score = 477 bits (1227), Expect = e-132
Identities = 400/1736 (23%), Positives = 760/1736 (43%), Gaps = 43/1736 (2%)
Frame = +1
Query: 1108 REGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLA--ARFNRKAEMRETWLTEN 1281
R + D++ + L+K + V + + ++ L+Q +FNR+A+ E + +
Sbjct: 1172 RRNPTLVDVS---ERLDKLHGLYQAVTSDWIAKEAWLQQCLDLQQFNREADQIEATTSSH 1228
Query: 1282 QRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINE 1461
+ + + G L VEA K+HE E + A ++R N++D+ IN+
Sbjct: 1229 EAFLEFTDLGESLDDVEALLKQHEKFENTLHAQDDRLKAFSDTADKLIAQNHYDKDYIND 1288
Query: 1462 RKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLM 1641
R+ V RR L+ S Q+ F K + S++ L
Sbjct: 1289 RRNQVLARRNQVKDAAQRRRAALKASEHYQQ-FSAEVDDLRDWLGDKMKTASDESYRDLN 1347
Query: 1642 DVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPG-TIDERSDVL 1818
++E LQKH E ++ R N +A Y+ + G T+ E +D
Sbjct: 1348 NLERKLQKHEAFEREL-----RANEGQLRAVNKAGKALISEENYRSDDVGETLKELND-- 1400
Query: 1819 QKRYKELLDLAAERKRRLEDNKRLCQFWWD--VAELEHGIKEQEQVLSSTDTGRDIVTVS 1992
++ +L+DL+ E+ RRL + CQ ++ + + ++E E L S G D+ +
Sbjct: 1401 --QWNQLVDLSLEKGRRL--RQAACQHGYNRTMEDARLKLEEIENCLQSKQVGVDLRSCK 1456
Query: 1993 HLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNI-------PPRLAEIRDYIN 2151
LL KH+ E+++ E+ +D L V G+E+ E + + ++ E+ D ++
Sbjct: 1457 ELLKKHQTLESDMCQWEQKVDDLVVMGEEMAHEGHFDALGLLEEYWVSRGKIRELCDVLD 1516
Query: 2152 K----LKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLL 2319
+ L+E +A R + L ++ +FF +A +V+ +L + V+SS D G+D LL
Sbjct: 1517 EAWRGLQEKAAERNKDLELSLKAQEFFFEAGEVESWLNEKNDVLSSTDYGRDRDAATKLL 1576
Query: 2320 KKHDDVHDELQNFDQHIKVL-HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRK 2496
KH V EL ++ + + H A + + + I + +Q L+ L+ +R+
Sbjct: 1577 TKHKAVELELDTYNGIVTEMGHTAAIMINAKHPDSKAIANKQQAIAQQMRALQRLATVRQ 1636
Query: 2497 QRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQE 2676
QRL++++ ++ + ++ +E WI E+ + A+ G+D E + I++ +F+ + ++
Sbjct: 1637 QRLMESMYRHEYFLESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKHRIEAGS 1696
Query: 2677 AKVTNVNDLARQLLNVEHPNSDDILHRQNKL------------------NARWAQLRDMV 2802
+ +LAR+L+ E P DI RQ +L W L ++
Sbjct: 1697 ERFNQCEELARKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIKESWKHLLGLI 1756
Query: 2803 DQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERD 2982
+ L+ A + F D E ++ I++K L + L DL+ V+ L RR E D
Sbjct: 1757 RNREQRLQAAGEIHRFHRDVAEALSRIQEKEAALPED--LGRDLNSVLALIRRHEGFEND 1814
Query: 2983 LGAIQAKLDSLHKEADDIERERP-QEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGD 3159
L A++A+L L ++A ++ P A I + + + W+ L ++ +L + D
Sbjct: 1815 LVALEAQLQVLVEDASRLQAHYPGNNAVHIDQQQQIVVAHWEELKERSALRRDQLQASCD 1874
Query: 3160 LQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRA 3339
LQRFL + W + +++E++ + A A+ L +H A++ EI+ + + +
Sbjct: 1875 LQRFLTQVRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFSSVLD 1934
Query: 3340 MGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEV 3519
+G+ + Q + + ++ L + ++L W ++ L Q ++L FLRDAKQ +
Sbjct: 1935 LGEAMVQ-TGHYAALEVEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQLDN 1993
Query: 3520 MLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAA 3699
+ + QE L+ D+ S+E+ + Q+K+H +F + +EK+ A+ GD+L H+ +
Sbjct: 1994 LSTTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNHFDS 2053
Query: 3700 DKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY 3879
I ++ + +RR R ++L+ L QF+ D E WI EK + + E
Sbjct: 2054 PTIARRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEKQKKLEAEAS 2113
Query: 3880 R----DAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELA 4047
+ + K +HQAFQ+ELAAN+ R++++K L K I Q+E L
Sbjct: 2114 KGEVSSLEDKIKKLQKHQAFQAELAANQSRIEEIKTKGERLLQQKHPASAEIRQQLEHLH 2173
Query: 4048 TQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAM 4227
W +L + +G+ L +A + + ++ W E + D D
Sbjct: 2174 ASWRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYEHCLSLQ 2233
Query: 4228 QKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPD-ELENIKAHRLAVQEQLQRLQAPLDDR 4404
+K ++++M I D E + I+ R + + + LQ L
Sbjct: 2234 RKLDDVDSDMRVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKWKGLQGALSTY 2293
Query: 4405 RKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNH 4584
R+ L F RD+DD + E+ V ++G+ LP LQ+ + + ++
Sbjct: 2294 REMLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQEAMERDMTAI 2353
Query: 4585 EPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFL 4764
E + + +EL + P + EL+S W +L+ + R+ L ++ H+F
Sbjct: 2354 EGKLKEHKAEARELSLKYPDKAPQINGILSELQSNWDDLQRFTQHRREALNQAYTLHKFQ 2413
Query: 4765 YDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKF 4944
D E E W+++ M + E + ++ H+ +++ID DT +AL K
Sbjct: 2414 ADLHELELWVADTIKRMDESEPPTTISEAEALLELHQERKAEIDGRQDTFKALKEHGQKL 2473
Query: 4945 VEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKE 5124
+ + E ++ +EKL GL + + D W+A KE
Sbjct: 2474 L----TINEDVKDNLEHLEKLRQGLANAWETKRQKLTQAHQLQLFKEQADQADSWLATKE 2529
Query: 5125 VVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIAL 5304
+ + G+ V+ L + ++F + + S R+ + ++ H DA I
Sbjct: 2530 AFLNNDDLGESLSGVEALLRKHEEFEKMLISQLS-RIEELEKFANEILSKEHADASVIKQ 2588
Query: 5305 WKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSS 5484
S+ + L R + L S LH+F + + + +K D+ RDSS+
Sbjct: 2589 RLASVCTRRDKLQNNARARRKKLLESHHLHQFLRNIYEVEGWLHQKQQVASDESYRDSSN 2648
Query: 5485 VGALSRKHQNYLKDIAAIGEQVAQI--ERDAAELRDGYAGDKALDIGSRESEVVKAWRHL 5658
+ + +KH + ++ A +VA + E +A + YA I R E+ WR L
Sbjct: 2649 LQSKIQKHVAFESELMANKGRVAAVVNEGEALIEENHYASS---SIQERLDELEAEWRLL 2705
Query: 5659 RGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSL 5838
+ + + +RL D F + + WMDE++ ++ S++ KD+S V L+ H +L
Sbjct: 2706 QETSELKKNRLNDAYQALLFGRTLDEFETWMDEIETQLQSEDHGKDLSSVANLLKRHTNL 2765
Query: 5839 KAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLI 6018
+ ++ E + G+ L+ + ++I K+ + + ++ R + L
Sbjct: 2766 ENDVLGHNEAYE-----GQKLIQENNPEKTKILMKIDETKQQWEDLKELAHARQDALAGA 2820
Query: 6019 LEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEER 6186
+V+ F R A SW+ +E L S YG +LE L++KH+ FE A +E+
Sbjct: 2821 KQVHMFDRTADETISWIQEKETALSSDGYGHDLETIQALVRKHQGFETDLGAVKEQ 2876
Score = 447 bits (1151), Expect = e-123
Identities = 408/1853 (22%), Positives = 794/1853 (42%), Gaps = 52/1853 (2%)
Frame = +1
Query: 862 KMINRYETLSS---DLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDE 1032
K Y+ S+ DL +W+ K++ ++ + + L ++R+L + + + +
Sbjct: 1312 KASEHYQQFSAEVDDLRDWLGDKMKTASDESYRD-LNNLERKLQKHEAFERELRA----N 1366
Query: 1033 KGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQE 1212
+G+L + ++ + N R G+ + ++N W L E+
Sbjct: 1367 EGQLRAVNKAGKALISEENYRS--DDVGETLKELNDQWNQLVDLSLEKG----------R 1414
Query: 1213 KLEQLAAR--FNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEE 1386
+L Q A + +NR E L E + + G DL S + KKH+ +E+D+ +E+
Sbjct: 1415 RLRQAACQHGYNRTMEDARLKLEEIENCLQSKQVGVDLRSCKELLKKHQTLESDMCQWEQ 1474
Query: 1387 RXXXXXXXXXXXXXXNYHD-----------QAKINERKENVXXXXXXXXXXXXARRVRLE 1533
+ + D + KI E + + R LE
Sbjct: 1475 KVDDLVVMGEEMAHEGHFDALGLLEEYWVSRGKIRELCDVLDEAWRGLQEKAAERNKDLE 1534
Query: 1534 LSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVN 1713
LS+ Q+ F L S D G LL KH +E +++ V
Sbjct: 1535 LSLKAQEFFFEAGEVESWLNEKNDVLSSTDYGRDRDAATKLLTKHKAVELELDTYNGIVT 1594
Query: 1714 NSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLC 1893
A N PD I + + ++ + L LA R++RL ++
Sbjct: 1595 EMGHTAAIMINAKHPDSKA--------IANKQQAIAQQMRALQRLATVRQQRLMESMYRH 1646
Query: 1894 QFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSG 2073
+++ + ELE IKEQEQ +S D G+D + L AK + ++ + + ++ +
Sbjct: 1647 EYFLESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKHRIEAGSERFNQCEELA 1706
Query: 2074 KEL-------------QDESIPGSDNIPPRLAE-----IRDYINKLKELSASRKERLAGG 2199
++L + E + D+ P R + I++ L L +R++RL
Sbjct: 1707 RKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIKESWKHLLGLIRNREQRLQAA 1766
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVL 2379
E ++F D + + + + ED+G+D +V L+++H+ ++L + ++VL
Sbjct: 1767 GEIHRFHRDVAEALSRIQEKEAALP-EDLGRDLNSVLALIRRHEGFENDLVALEAQLQVL 1825
Query: 2380 HAKAESL----PQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDAD 2547
A L P H D +Q++ + EL+ S LR+ +L + L + +
Sbjct: 1826 VEDASRLQAHYPGNNAVHIDQQQQI--VVAHWEELKERSALRRDQLQASCDLQRFLTQVR 1883
Query: 2548 SVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE 2727
+ +W ++T RD +I+K + L+ +++ +E ++V DL ++
Sbjct: 1884 DLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFSSVLDLGEAMVQTG 1943
Query: 2728 HPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
H + ++ + N+L +L QK+ L++ L F D ++ + L
Sbjct: 1944 HYAALEVEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQLDNLSTTQEAALS 2003
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERER----PQEAQAIRE 3075
D + + V ++ + E+ L + KL +L + D + + P A+ + E
Sbjct: 2004 -GDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNHFDSPTIARRLSE 2062
Query: 3076 DIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV---ASEEEPQ 3246
++R ++ ++ + + R EA L A +F+RD+ ++W+ Q+++ AS+ E
Sbjct: 2063 VVQRRARIRNLCDARRRRLEAGLLHA----QFVRDVAEAESWIGEKQKKLEAEASKGEVS 2118
Query: 3247 SLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWE 3426
SL + + L +H A + E+ ++++ G+R+ Q Q P +RQ+L L W
Sbjct: 2119 SLEDKIKKLQKHQAFQAELAANQSRIEEIKTKGERLLQ-QKHPASAEIRQQLEHLHASWR 2177
Query: 3427 ELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQ 3606
+L NR L + ++ F ++ E + +E + D + E + ++
Sbjct: 2178 KLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYEHCLSLQRKLD 2237
Query: 3607 DFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKK-L 3783
D + M +D +I+ + D+L + G K ++ R+ + + A ++ L
Sbjct: 2238 DVDSDMRVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKWKGLQGALSTYREML 2297
Query: 3784 KDALSLQQFLSDCDELREWIEEKMIRAQD-ETYRDAKTITSKFVRHQAFQSELAANKERL 3960
AL + F D D+ + + EK + + +D + + +A + ++ A + +L
Sbjct: 2298 AGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQEAMERDMTAIEGKL 2357
Query: 3961 DQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
+ K A L P+ I+ + EL + WD+L++ T+ + + L A + +
Sbjct: 2358 KEHKAEARELSLKYPDKAPQINGILSELQSNWDDLQRFTQHRREALNQAYTLHKFQADLH 2417
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
+++ W M + P TT++ A + L+E +KA+ ID H
Sbjct: 2418 ELELWVADTIKRMDESEPP---TTISEA---EALLELHQERKAE-IDGRQDTFKALKE-H 2469
Query: 4321 PDEL----ENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERL 4488
+L E++K + +++ Q L + +R+ L + F D W++ +
Sbjct: 2470 GQKLLTINEDVKDNLEHLEKLRQGLANAWETKRQKLTQAHQLQLFKEQADQADSWLATKE 2529
Query: 4489 VLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKK 4668
+LGESL L + + + + I ++ E++ + HA+ +++
Sbjct: 2530 AFLNNDDLGESLSGVEALLRKHEEFEKMLISQLSRIEELEKFANEILSKEHADASVIKQR 2589
Query: 4669 IQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFS 4848
+ + + +L+ + R+ L ES HQFL + E E W+ +++ + DE +D +
Sbjct: 2590 LASVCTRRDKLQNNARARRKKLLESHHLHQFLRNIYEVEGWLHQKQ-QVASDESYRDSSN 2648
Query: 4849 TKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDX 5028
+++I+KH +S++ + A+ + +EE + IQ R ++E + LQ+
Sbjct: 2649 LQSKIQKHVAFESELMANKGRVAAVVNEGEALIEENHYASSSIQERLDELEAEWRLLQET 2708
Query: 5029 XXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARD 5208
R +D+ W+ + E S+++G+D V L +R D
Sbjct: 2709 SELKKNRLNDAYQALLFGRTLDEFETWMDEIETQLQSEDHGKDLSSVANLLKRHTNLEND 2768
Query: 5209 TENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRL 5388
+G A +G LI + + I + D + WE+L EL R L ++
Sbjct: 2769 V--LGHNE---AYEG-QKLIQENNPEKTKILMKIDETKQQWEDLKELAHARQDALAGAKQ 2822
Query: 5389 LHKFYHDCRDCLSRIMEKTHAMPDD-LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIER 5565
+H F + +S I EK A+ D G D ++ AL RKHQ + D+ A+ EQV +
Sbjct: 2823 VHMFDRTADETISWIQEKETALSSDGYGHDLETIQALVRKHQGFETDLGAVKEQVELLMD 2882
Query: 5566 DAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLL 5745
+A+ L + + D I + E W L R S+L L ++ RDL+
Sbjct: 2883 EASRLIELFP-DARSHIEVKHQEAEATWNELLEKAAQRRSKLSQAEQLQAYLGEYRDLMS 2941
Query: 5746 WMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYAS 5925
W++E+ ++ + E +DV G E L+ H K EI+ R E F+ G++L+ H+ +
Sbjct: 2942 WINEMVAKVTAPELARDVPGAEALILRHNEYKTEIETRNEAFDKFYKTGQELIEEGHFMA 3001
Query: 5926 SEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEY 6105
EIE+K+ L + + WE R + L+ F RDA E+W+ ++EP L +
Sbjct: 3002 REIEEKVSVLQHRQQFLKDTWEQRRHIYEQNLDTQLFKRDAETLENWIVSREPMLNDGKL 3061
Query: 6106 GRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRR 6264
G ++ + +LI+KHE FEK+ AQEERF AL+++T E + ++ E A R+
Sbjct: 3062 GESISQVEELIRKHEDFEKTIEAQEERFNALKRITMLEKAFQKQQKAEMAARQ 3114
Score = 427 bits (1098), Expect = e-117
Identities = 435/1989 (21%), Positives = 820/1989 (40%), Gaps = 39/1989 (1%)
Frame = +1
Query: 811 IQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEF 990
+Q K++G + E ++ +++TL SD+ +W K+ L E EG
Sbjct: 1443 LQSKQVGVDLRSCKE---LLKKHQTLESDMCQW-EQKVDDLVVMGEEMAHEG-------- 1490
Query: 991 NDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEH 1170
FD G LE + + +R +L ++ AW+ L++
Sbjct: 1491 ----------HFDALGLLEEY-WVSRGKIR------------ELCDVLDEAWRGLQEKAA 1527
Query: 1171 ERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKH 1350
ER L+ L QE F +A E+WL E ++S ++G D + KH
Sbjct: 1528 ERNKDLELSLKAQE--------FFFEAGEVESWLNEKNDVLSSTDYGRDRDAATKLLTKH 1579
Query: 1351 EAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRL 1530
+A+E ++ Y + D I +++ + R+ RL
Sbjct: 1580 KAVELELDTYNGIVTEMGHTAAIMINAKHPDSKAIANKQQAIAQQMRALQRLATVRQQRL 1639
Query: 1531 ELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERV 1710
SM + F + SED G + L K + I ER
Sbjct: 1640 MESMYRHEYFLESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKHRIEAGSERF 1699
Query: 1711 NNSIAQAQRFRNPDGP---------DGSGYKPVEP-GTIDERSDVLQKRYKELLDLAAER 1860
N A++ + P + G +P + + D++++ +K LL L R
Sbjct: 1700 NQCEELARKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIKESWKHLLGLIRNR 1759
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
++RL+ + +F DVAE I+E+E L D GRD+ +V L+ +H+ EN+L L
Sbjct: 1760 EQRLQAAGEIHRFHRDVAEALSRIQEKEAALPE-DLGRDLNSVLALIRRHEGFENDLVAL 1818
Query: 2041 EKYLDRLDVSGKELQDESIPGSD--NIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQ 2214
E L L LQ PG++ +I + + + +LKE SA R+++L + +
Sbjct: 1819 EAQLQVLVEDASRLQAH-YPGNNAVHIDQQQQIVVAHWEELKERSALRRDQLQASCDLQR 1877
Query: 2215 FFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAE 2394
F T D+ + MS+ED +D + Q+L +H+ + E++ + + E
Sbjct: 1878 FLTQVRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFSSVLDLGE 1937
Query: 2395 SLPQEAREHP-DIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDE 2571
++ Q ++ ++ + L ++ +L + Q +K L + L+ DA +++
Sbjct: 1938 AMVQTGHYAALEVEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQLDNLSTT 1997
Query: 2572 KGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDIL 2751
+ L+ G +EEV+ + + E+ + QE K+T + + +LL H +S I
Sbjct: 1998 QEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNHFDSPTIA 2057
Query: 2752 HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTND 2931
R +++ R A++R++ D +R LE F D E +WI +K + LE ++A +
Sbjct: 2058 RRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEKQKKLE-AEASKGE 2116
Query: 2932 LSG----VMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQV 3099
+S + KLQ+ + + +L A Q++++ + + + + +++ + IR+ ++ +H
Sbjct: 2117 VSSLEDKIKKLQKHQAF-QAELAANQSRIEEIKTKGERLLQQKHPASAEIRQQLEHLHAS 2175
Query: 3100 WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQ 3279
W L + L+EA D+ F ++ +AW+ + V + + + L +
Sbjct: 2176 WRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYEHCLSLQRK 2235
Query: 3280 HAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQH 3459
+ ++ K + A+ D++ + D + ++QR W+ LQ +
Sbjct: 2236 LDDVDSDMRVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKWKGLQGALSTYRE 2295
Query: 3460 LLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDE 3639
+L+ L + +F RD + ++ + DI + L E+ ++ + M A +
Sbjct: 2296 MLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQEAMERDMTAIEG 2355
Query: 3640 KIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSD 3819
K++ +L A +I+ + + Q + L A +L +F +D
Sbjct: 2356 KLKEHKAEARELSLKYPDKAPQINGILSELQSNWDDLQRFTQHRREALNQAYTLHKFQAD 2415
Query: 3820 CDELREWIEEKMIRAQDE----TYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAA-- 3981
EL W+ + + R + T +A+ + HQ ++E+ ++ LK
Sbjct: 2416 LHELELWVADTIKRMDESEPPTTISEAEALLEL---HQERKAEIDGRQDTFKALKEHGQK 2472
Query: 3982 -INLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWA 4158
+ + +D + ++ + LA W E K QKL A++ QL+ + W
Sbjct: 2473 LLTINEDVKDNLEHLEKLRQGLANAW-------ETKRQKLTQAHQLQLFKEQADQADSWL 2525
Query: 4159 TQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELEN 4338
E + +D L+ V ++K E +I + I+ +
Sbjct: 2526 ATKEAFLNNDDLGESLSGVEALLRKHEEFEKMLISQLSRIEELEKFANEILSKEHADASV 2585
Query: 4339 IKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGE 4518
IK +V + +LQ RRK L QF R++ + + W+ ++ +A ++ +
Sbjct: 2586 IKQRLASVCTRRDKLQNNARARRKKLLESHHLHQFLRNIYEVEGWLHQKQQVASDESYRD 2645
Query: 4519 SLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQE 4698
S ++QK++ S E+ ++ + + N G+ LI+E H + ++++ EL + W+
Sbjct: 2646 SSNLQSKIQKHVAFES-ELMANKGRVAAVVNEGEALIEENHYASSSIQERLDELEAEWRL 2704
Query: 4699 LKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHER 4878
L+E + +K L ++ +A F E E WM E E + ++ GKD S N +K+H
Sbjct: 2705 LQETSELKKNRLNDAYQALLFGRTLDEFETWMDEIETQLQSEDHGKDLSSVANLLKRHTN 2764
Query: 4879 LQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXX 5058
L++D+ + A + K ++E +P +I ++ + ++ + L++
Sbjct: 2765 LENDVLGHNE-----AYEGQKLIQENNPEKTKILMKIDETKQQWEDLKELAHARQDALAG 2819
Query: 5059 XXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVA 5238
+ R D+ + WI +KE S G D E +Q L + Q F D + E+V
Sbjct: 2820 AKQVHMFDRTADETISWIQEKETALSSDGYGHDLETIQALVRKHQGFETDLGAV-KEQVE 2878
Query: 5239 NANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
D LI I + W LLE R L + L + + RD
Sbjct: 2879 LLMDEASRLIELFPDARSHIEVKHQEAEATWNELLEKAAQRRSKLSQAEQLQAYLGEYRD 2938
Query: 5419 CLSRIMEKTHAMP-DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL-RDGY 5592
+S I E + +L RD AL +H Y +I E + + EL +G+
Sbjct: 2939 LMSWINEMVAKVTAPELARDVPGAEALILRHNEYKTEIETRNEAFDKFYKTGQELIEEGH 2998
Query: 5593 AGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREM 5772
A +I + S + + L+ + R D F L W+ + +
Sbjct: 2999 F--MAREIEEKVSVLQHRQQFLKDTWEQRRHIYEQNLDTQLFKRDAETLENWIVSREPML 3056
Query: 5773 NSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIK 5952
N + + +S VE L+ H+ + I+A+EE FNA + +L + + E +
Sbjct: 3057 NDGKLGESISQVEELIRKHEDFEKTIEAQEERFNALKRI--TMLEKAFQKQQKAEMAARQ 3114
Query: 5953 LTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEE--- 6123
ER E R E + + +Q I E R L + + E+ EE
Sbjct: 3115 AEKERIERARLEERKRKEVQRITE----ERKREEERRRLLDSPHHAVHDEFNGTTEEHES 3170
Query: 6124 -----TIKLIKKHEAFEKSAFAQEERFLAL--EKL--TTFELKETQHREEETAK-RRGPA 6273
+K E + + + + EKL TT ++K + + +T K +R P+
Sbjct: 3171 INKLSPLKASTTTEGLDSTPVQKSHGISHVFGEKLRRTTPDIKRAESMKVDTKKPKRTPS 3230
Query: 6274 HIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQ 6453
+ R T + ++ A +G L RKH +S +KAA RSW++ Y VL
Sbjct: 3231 F--TTRRRTQSFRKLQRMENMDALPPVEIQGLLERKHELQSAGKKAAVRSWKQYYTVLCG 3288
Query: 6454 NELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEE 6633
L F+KD + S P+ + A DY KKKNV L+ G+E+LF S++
Sbjct: 3289 QLLCFFKDMEDFTSSKAATAPITIFNAICEKADDYTKKKNVFRLKCTDGSEFLFLAPSQQ 3348
Query: 6634 DMQRWLTEL 6660
+M+ W+ ++
Sbjct: 3349 EMEDWVNKI 3357
Score = 405 bits (1041), Expect = e-111
Identities = 370/1747 (21%), Positives = 729/1747 (41%), Gaps = 44/1747 (2%)
Frame = +1
Query: 1156 EKAEHERELVLKEELIRQEKLEQLAAR---FNRKAEMRETWLTENQRLVSQDNFGNDLSS 1326
+K +E L+E +R+ L + A R F R+ + E W+ + ++++ D+ +
Sbjct: 870 QKKINETYSELQELALRRHALLEDAIRLYGFYRECDDFEKWIKDKEKMLRIDD---PRDN 926
Query: 1327 VEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXX 1506
VE A +K+E TD+ A +R + K+ R+ ++
Sbjct: 927 VETAKRKYEKFLTDLSASGKRVEAIDAAVDEFVRQGHSQLDKVKARQRHIHQLWDHLNWL 986
Query: 1507 XXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESD 1686
+ LE + +++ ++L + +LG L V+ L ++H LE +
Sbjct: 987 KTQKEKSLEGASSVELFNRTCDEAHDWMLEKITQLDTAELGPDLKTVQALQRRHQHLERE 1046
Query: 1687 INIIGERVN--NSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAER 1860
+ + E+V N +A + + S Y P E ++ R + +++ + ++ A ER
Sbjct: 1047 LAPVEEKVRKVNLLANSVK---------SSY-PHELNNVNARQNEIKELWNQVQTKAKER 1096
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
+ RLED F L + + ++ + + RD+ T L H ++R
Sbjct: 1097 RSRLEDAVGQQIFMNSSKNLINWAVDIQETMKVEEPVRDVATAEQLRKHHIELGEDIRTR 1156
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
E ++ G +L + P ++ RL ++ + +++ L ++ QF
Sbjct: 1157 EDEFREVEELGNQLLRRN-PTLVDVSERLDKLHGLYQAVTSDWIAKEAWLQQCLDLQQFN 1215
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
+AD ++ + D+G+ V+ LLK+H+ + L D +K A+ L
Sbjct: 1216 READQIEATTSSHEAFLEFTDLGESLDDVEALLKQHEKFENTLHAQDDRLKAFSDTADKL 1275
Query: 2401 PQEAREHPD---IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDE 2571
A+ H D I R + L ++ ++++ +Q R+ L + + ++ D + W+ +
Sbjct: 1276 --IAQNHYDKDYINDRRNQVLARRNQVKDAAQRRRAALKASEHYQQFSAEVDDLRDWLGD 1333
Query: 2572 KGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDIL 2751
K K A+ RD+ +E + + E++++ E ++ VN + L++ E+ SDD+
Sbjct: 1334 KMK-TASDESYRDLNNLERKLQKHEAFERELRANEGQLRAVNKAGKALISEENYRSDDVG 1392
Query: 2752 HRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTND 2931
+LN +W QL D+ +K L +A + ++ +E+ L+ S + D
Sbjct: 1393 ETLKELNDQWNQLVDLSLEKGRRLRQAACQHGYNRTMEDARLKLEEIENCLQ-SKQVGVD 1451
Query: 2932 LSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQA-----------IRED 3078
L +L ++ +E D+ + K+D L +++ E +A IRE
Sbjct: 1452 LRSCKELLKKHQTLESDMCQWEQKVDDLVVMGEEMAHEGHFDALGLLEEYWVSRGKIREL 1511
Query: 3079 IKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAE 3258
+ + W L +K E L+ + Q F + ++WL ++S + +
Sbjct: 1512 CDVLDEAWRGLQEKAAERNKDLELSLKAQEFFFEAGEVESWLNEKNDVLSSTDYGRDRDA 1571
Query: 3259 AEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQR 3438
A +LL +H A+ E+D Y +M + + P + + + + LQR
Sbjct: 1572 ATKLLTKHKAVELELDTYNGIVTEMGHTA-AIMINAKHPDSKAIANKQQAIAQQMRALQR 1630
Query: 3439 MWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFIT 3618
+ RQ L + + + ++++ E + +QE A +D Q E + DF
Sbjct: 1631 LATVRQQRLMESMYRHEYFLESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKH 1690
Query: 3619 TMDANDEKIRAVGMFGDQLCQDGHYAADKIHKK-----------ARNIDERRGANREKAQ 3765
++A E+ +L + I K+ R + + +E +
Sbjct: 1691 RIEAGSERFNQCEELARKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIKESWK 1750
Query: 3766 EVL-------KKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQA 3924
+L ++L+ A + +F D E I+EK ++ RD ++ + RH+
Sbjct: 1751 HLLGLIRNREQRLQAAGEIHRFHRDVAEALSRIQEKEAALPEDLGRDLNSVLALIRRHEG 1810
Query: 3925 FQSELAANKERLDQLKHAAINLGDDKPEYHGT-IDPQIEELATQWDELEKTTEEKGQKLF 4101
F+++L A + +L L A L P + ID Q + + W+EL++ + + +L
Sbjct: 1811 FENDLVALEAQLQVLVEDASRLQAHYPGNNAVHIDQQQQIVVAHWEELKERSALRRDQLQ 1870
Query: 4102 DANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHID 4281
+ Q ++ + D+ WA L M+ ED+ D + + + ++ E+ +
Sbjct: 1871 ASCDLQRFLTQVRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFS 1930
Query: 4282 XXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDD 4461
++ + ++ Q+L + ++ L++ F RD
Sbjct: 1931 SVLDLGEAMVQTGHYAALEVEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQ 1990
Query: 4462 EKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGH 4641
+ + N G+S+ + K + E + + +G +L+ + H
Sbjct: 1991 LDNLSTTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNH 2050
Query: 4642 ANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQ 4821
+ P +++ E+ ++ R+ L QF+ D EAE+W+ E++ ++
Sbjct: 2051 FDSPTIARRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEKQ-KKLE 2109
Query: 4822 DERGKDEFSTK----NQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQ 4989
E K E S+ +++KH+ Q+++ I + TK + +++K P + +I+ +
Sbjct: 2110 AEASKGEVSSLEDKIKKLQKHQAFQAELAANQSRIEEIKTKGERLLQQKHPASAEIRQQL 2169
Query: 4990 AQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHV 5169
+ + L + +++ + WI DKE++ + + G+DYEH
Sbjct: 2170 EHLHASWRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYEHC 2229
Query: 5170 QMLQERFQQFARDTENIGSERVANANDGCDTLIGHGH-TDAPTIALWKDSLNEAWENLLE 5346
LQ + D + R+ N D LI G ++ I +DS N W+ L
Sbjct: 2230 LSLQRKLDDVDSDM-RVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKWKGLQG 2288
Query: 5347 LMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLK 5523
+ T ++L + +H F D D R++EK+ AM D+G+D +V L RK + +
Sbjct: 2289 ALSTYREMLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQEAMER 2348
Query: 5524 DIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTS 5703
D+ AI ++ + + +A EL Y DKA I SE+ W L+ R L
Sbjct: 2349 DMTAIEGKLKEHKAEARELSLKYP-DKAPQINGILSELQSNWDDLQRFTQHRREALNQAY 2407
Query: 5704 DLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACI 5883
L KF + +L LW+ + + M+ E P +S E L+ HQ KAEID R++ F A
Sbjct: 2408 TLHKFQADLHELELWVADTIKRMDESEPPTTISEAEALLELHQERKAEIDGRQDTFKALK 2467
Query: 5884 SLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAES 6063
G+ LL + +++ L L R + WE + + L ++ F A A+S
Sbjct: 2468 EHGQKLLT----INEDVKDNLEHLEKLRQGLANAWETKRQKLTQAHQLQLFKEQADQADS 2523
Query: 6064 WLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHRE 6243
WL +E +L + + G +L L++KHE FEK +Q R LEK E+ +H +
Sbjct: 2524 WLATKEAFLNNDDLGESLSGVEALLRKHEEFEKMLISQLSRIEELEKFAN-EILSKEHAD 2582
Query: 6244 EETAKRR 6264
K+R
Sbjct: 2583 ASVIKQR 2589
Score = 397 bits (1021), Expect = e-108
Identities = 336/1527 (22%), Positives = 655/1527 (42%), Gaps = 30/1527 (1%)
Frame = +1
Query: 724 VNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLL 903
+N PD K+I L+ R+ V + + + Y S +L
Sbjct: 1604 INAKHPDSKAIANKQQAIAQQMRALQ-------RLATVRQQRLMESMYRHEYFLESRELE 1656
Query: 904 EWINAKIQLLNERHFENNLEGVQRQLTEFNDY--RTQEKPPKFDEKGELEVLLFTLQSAM 1077
+WI + Q + + E + +FND+ R + +F++ EL
Sbjct: 1657 QWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKHRIEAGSERFNQCEELA---------- 1706
Query: 1078 RANNQRPFVPREGKLIADINRAWQSLEKAEHE--RELVLKEELI-------------RQE 1212
R + E I DI + + L + + + R++ + +LI R++
Sbjct: 1707 -----RKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIKESWKHLLGLIRNREQ 1761
Query: 1213 KLEQLAA--RFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEE 1386
+L+ RF+R + + E + + +D G DL+SV A ++HE E D+ A E
Sbjct: 1762 RLQAAGEIHRFHRDVAEALSRIQEKEAALPED-LGRDLNSVLALIRRHEGFENDLVALEA 1820
Query: 1387 RXXXXXXXXXXXXXXNYHDQA-KINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFH 1563
+ + A I+++++ V RR +L+ S +Q+
Sbjct: 1821 QLQVLVEDASRLQAHYPGNNAVHIDQQQQIVVAHWEELKERSALRRDQLQASCDLQRFLT 1880
Query: 1564 XXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFR 1743
+++ + +ED + L +H L+ +I + ++ + +
Sbjct: 1881 QVRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFSSVLDLGEAMV 1940
Query: 1744 NPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELE 1923
Y +E ++E+ + L ++L ++K L+ L F D +L+
Sbjct: 1941 QT-----GHYAALE---VEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQLD 1992
Query: 1924 HGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPG 2103
+ QE LS + G + V + KH E L E+ L L G +L ++
Sbjct: 1993 NLSTTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNHFD 2052
Query: 2104 SDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSED 2283
S I RL+E+ +++ L +R+ RL G+ + QF D + + ++ + + + +E
Sbjct: 2053 SPTIARRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEKQKKLEAE- 2111
Query: 2284 VGKDEGTVQLL------LKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHP---DIRQ 2436
+G V L L+KH EL I+ + K E L Q+ +HP +IRQ
Sbjct: 2112 --ASKGEVSSLEDKIKKLQKHQAFQAELAANQSRIEEIKTKGERLLQQ--KHPASAEIRQ 2167
Query: 2437 RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIE 2616
+L+ +L S R + L +A + + + + +E+WI +K ++ G+D E
Sbjct: 2168 QLEHLHASWRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYE 2227
Query: 2617 EVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN-SDDILHRQNKLNARWAQLR 2793
++ + D ++ DM+ ++++ +N LA +L+ N S I R++ N +W L+
Sbjct: 2228 HCLSLQRKLDDVDSDMRVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKWKGLQ 2287
Query: 2794 DMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMM 2973
+ R L A + F D +T + +K+ + +D + DL V LQR+ M
Sbjct: 2288 GALSTYREMLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTD-IGKDLPAVEHLQRKQEAM 2346
Query: 2974 ERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEA 3153
ERD+ AI+ KL EA ++ + P +A I + + WD L + + L++A
Sbjct: 2347 ERDMTAIEGKLKEHKAEARELSLKYPDKAPQINGILSELQSNWDDLQRFTQHRREALNQA 2406
Query: 3154 GDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKM 3333
L +F DL + W+ T +++ E P +++EAE LL H + EIDG + +K +
Sbjct: 2407 YTLHKFQADLHELELWVADTIKRMDESEPPTTISEAEALLELHQERKAEIDGRQDTFKAL 2466
Query: 3334 RAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQA 3513
+ G ++ D ++ L L++ + L W+ ++ L+Q LQ+F A QA
Sbjct: 2467 KEHGQKLLTINED-----VKDNLEHLEKLRQGLANAWETKRQKLTQAHQLQLFKEQADQA 2521
Query: 3514 EVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHY 3693
+ L+ +E +L DD+ +SL E L++H++F + + +I + F +++ H
Sbjct: 2522 DSWLATKEAFLNNDDLGESLSGVEALLRKHEEFEKMLISQLSRIEELEKFANEILSKEHA 2581
Query: 3694 AADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDE 3873
A I ++ ++ RR + A+ KKL ++ L QFL + E+ W+ +K A DE
Sbjct: 2582 DASVIKQRLASVCTRRDKLQNNARARRKKLLESHHLHQFLRNIYEVEGWLHQKQQVASDE 2641
Query: 3874 TYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQ 4053
+YRD+ + SK +H AF+SEL ANK R+ + + L ++ +I +++EL +
Sbjct: 2642 SYRDSSNLQSKIQKHVAFESELMANKGRVAAVVNEGEALIEENHYASSSIQERLDELEAE 2701
Query: 4054 WDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK 4233
W L++T+E K +L DA + L+ +++ + + W ++E ++ ED DL++V +++
Sbjct: 2702 WRLLQETSELKKNRLNDAYQALLFGRTLDEFETWMDEIETQLQSEDHGKDLSSVANLLKR 2761
Query: 4234 QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKA 4413
+E +++ + + + E I ++Q + L+ R+ A
Sbjct: 2762 HTNLENDVLGHNEAYE-----GQKLIQENNPEKTKILMKIDETKQQWEDLKELAHARQDA 2816
Query: 4414 LERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPW 4593
L K F R D+ WI E+ + G L L + Q ++ +
Sbjct: 2817 LAGAKQVHMFDRTADETISWIQEKETALSSDGYGHDLETIQALVRKHQGFETDLGAVKEQ 2876
Query: 4594 INQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDC 4773
+ + + LI+ E K QE + W EL E R+ L ++E+ +L +
Sbjct: 2877 VELLMDEASRLIELFPDARSHIEVKHQEAEATWNELLEKAAQRRSKLSQAEQLQAYLGEY 2936
Query: 4774 GEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE 4953
+ +W++E + E +D + I +H +++I+ + + +EE
Sbjct: 2937 RDLMSWINEMVAKVTAPELARDVPGAEALILRHNEYKTEIETRNEAFDKFYKTGQELIEE 2996
Query: 4954 KSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVA 5133
+ +I+ + + ++ L+D R+ + L WI +E +
Sbjct: 2997 GHFMAREIEEKVSVLQHRQQFLKDTWEQRRHIYEQNLDTQLFKRDAETLENWIVSREPML 3056
Query: 5134 GSQENGQDYEHVQMLQERFQQFARDTE 5214
+ G+ V+ L + + F + E
Sbjct: 3057 NDGKLGESISQVEELIRKHEDFEKTIE 3083
Score = 310 bits (794), Expect = 3e-82
Identities = 355/1717 (20%), Positives = 693/1717 (39%), Gaps = 63/1717 (3%)
Frame = +1
Query: 1237 FNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXX 1416
FNR + W+ E + G DL +V+A ++H+ +E ++ EE+
Sbjct: 1003 FNRTCDEAHDWMLEKITQLDTAELGPDLKTVQALQRRHQHLERELAPVEEKVRKVNLLAN 1062
Query: 1417 XXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXX 1596
H+ +N R+ + RR RLE ++ Q +
Sbjct: 1063 SVKSSYPHELNNVNARQNEIKELWNQVQTKAKERRSRLEDAVGQQIFMNSSKNLINWAVD 1122
Query: 1597 IKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGE--RVNNSIAQAQRFRNPDGPDGSG 1770
I+ + E+ + E L + H L DI + R + RNP D
Sbjct: 1123 IQETMKVEEPVRDVATAEQLRKHHIELGEDIRTREDEFREVEELGNQLLRRNPTLVD--- 1179
Query: 1771 YKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQV 1950
+ ER D L Y+ + ++ L+ L QF + ++E E
Sbjct: 1180 --------VSERLDKLHGLYQAVTSDWIAKEAWLQQCLDLQQFNREADQIEATTSSHEAF 1231
Query: 1951 LSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLA 2130
L TD G + V LL +H+ EN L + L + +L ++ D I R
Sbjct: 1232 LEFTDLGESLDDVEALLKQHEKFENTLHAQDDRLKAFSDTADKLIAQNHYDKDYINDRRN 1291
Query: 2131 EIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQ 2310
++ N++K+ + R+ L Y QF + DD+ +L D ++ S E +D ++
Sbjct: 1292 QVLARRNQVKDAAQRRRAALKASEHYQQFSAEVDDLRDWLGDKMKTASDESY-RDLNNLE 1350
Query: 2311 LLLKKHDDVHDELQNFDQHIKVLHAKAESL-PQEAREHPDIRQRLDTTLKQKAELENLSQ 2487
L+KH+ EL+ + ++ ++ ++L +E D+ + L Q +L +LS
Sbjct: 1351 RKLQKHEAFERELRANEGQLRAVNKAGKALISEENYRSDDVGETLKELNDQWNQLVDLSL 1410
Query: 2488 LRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMK 2667
+ +RL A + + ++E L + G D+ + + + TLE DM
Sbjct: 1411 EKGRRLRQAACQHGYNRTMEDARLKLEEIENCLQSKQVGVDLRSCKELLKKHQTLESDMC 1470
Query: 2668 NQEAKVTNVNDLARQLLNVEHPNSDDILHRQ-----------NKLNARWAQLRDMVDQKR 2814
E KV ++ + ++ + H ++ +L + L+ W L++ ++
Sbjct: 1471 QWEQKVDDLVVMGEEMAHEGHFDALGLLEEYWVSRGKIRELCDVLDEAWRGLQEKAAERN 1530
Query: 2815 NELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAI 2994
+LE + + + F + E +W+ +K VL +D D KL + +E +L
Sbjct: 1531 KDLELSLKAQEFFFEAGEVESWLNEKNDVLSSTD-YGRDRDAATKLLTKHKAVELELDTY 1589
Query: 2995 QAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFL 3174
+ + A + + +++AI + I Q L + + +L E+ +
Sbjct: 1590 NGIVTEMGHTAAIMINAKHPDSKAIANKQQAIAQQMRALQRLATVRQQRLMESMYRHEYF 1649
Query: 3175 RDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG--- 3345
+ + W+ ++ ASE+ Q L + + I+ +E + + +
Sbjct: 1650 LESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKHRIEAGSERFNQCEELARKL 1709
Query: 3346 ---------------DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLN 3480
+++ QD DP RQ ++E W+ L + NR+ L
Sbjct: 1710 IANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDL-IKESWKHLLGLIRNREQRLQAAGE 1768
Query: 3481 LQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGM 3660
+ F RD +A + ++E L +D+ + L ++RH+ F + A + +++ +
Sbjct: 1769 IHRFHRDVAEALSRIQEKEAAL-PEDLGRDLNSVLALIRRHEGFENDLVALEAQLQVLVE 1827
Query: 3661 FGDQLCQDGHYAADKIHKKARNIDERRG---ANREKAQEVLKKLKDAL----SLQQFLSD 3819
+L HY + A +ID+++ A+ E+ +E +D L LQ+FL+
Sbjct: 1828 DASRL--QAHYPGN----NAVHIDQQQQIVVAHWEELKERSALRRDQLQASCDLQRFLTQ 1881
Query: 3820 CDELREWIEE-KMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGD 3996
+L W + + ++ RDA + H+A + E+ A ++ + ++LG+
Sbjct: 1882 VRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFS----SVLDLGE 1937
Query: 3997 DKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDA-NRQQLYVQSIADMKEW---ATQ 4164
+ ++EE Q ++ QKL A ++++++ + D+ + A Q
Sbjct: 1938 AMVQTGHYAALEVEEKCNQ-------LLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQ 1990
Query: 4165 LENEMTRE------DQPGD-LTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
L+N T + D GD + V+ ++K + E ++ + + + +
Sbjct: 1991 LDNLSTTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNH 2050
Query: 4324 DELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKA 4503
+ I V ++ R++ D RR+ LE QF RDV + + WI E+ +A
Sbjct: 2051 FDSPTIARRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEKQKKLEA 2110
Query: 4504 Q-NLGE--SLPD-CHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKI 4671
+ + GE SL D +LQK+ Q E+ ++ I +I G+ L+ + H +++
Sbjct: 2111 EASKGEVSSLEDKIKKLQKH-QAFQAELAANQSRIEEIKTKGERLLQQKHPASAEIRQQL 2169
Query: 4672 QELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFST 4851
+ L ++W++L +R L E++ +F + EAW+ ++E+ + + GKD
Sbjct: 2170 EHLHASWRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYEHC 2229
Query: 4852 KNQIKKHERLQSDI---DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQ 5022
+ +K + + SD+ D TI ALA K K + + ++ IQ R+ + GLQ
Sbjct: 2230 LSLQRKLDDVDSDMRVDDSRIKTINALADKLIK--QGRDNESKAIQQRRDSFNNKWKGLQ 2287
Query: 5023 DXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFA 5202
+ +R+IDD Q + +K V + + G+D V+ LQ + +
Sbjct: 2288 GALSTYREMLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQEAME 2347
Query: 5203 RDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEAS 5382
RD I + + + + + + AP I L W++L R + L +
Sbjct: 2348 RDMTAIEGKLKEHKAEARELSLKY-PDKAPQINGILSELQSNWDDLQRFTQHRREALNQA 2406
Query: 5383 RLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQI 5559
LHKF D + + + M + + S AL HQ +I + +
Sbjct: 2407 YTLHKFQADLHELELWVADTIKRMDESEPPTTISEAEALLELHQERKAEIDGRQDTFKAL 2466
Query: 5560 ERDAAELRDGYAGDKALDIGSRESEVVKAWRHLR-GLCDA---RTSRLMDTSDLFKFMNM 5727
+ G K L I + ++ LR GL +A + +L L F
Sbjct: 2467 KEH---------GQKLLTINEDVKDNLEHLEKLRQGLANAWETKRQKLTQAHQLQLFKEQ 2517
Query: 5728 VRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLN 5907
W+ + +N+ + + +SGVE L+ H+ + + ++ ++L+
Sbjct: 2518 ADQADSWLATKEAFLNNDDLGESLSGVEALLRKHEEFEKMLISQLSRIEELEKFANEILS 2577
Query: 5908 RKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPY 6087
++H +S I+++L + T R ++ R + L ++QF R+ E WL Q+
Sbjct: 2578 KEHADASVIKQRLASVCTRRDKLQNNARARRKKLLESHHLHQFLRNIYEVEGWLH-QKQQ 2636
Query: 6088 LISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL 6198
+ S E R+ I+KH AFE A + R A+
Sbjct: 2637 VASDESYRDSSNLQSKIQKHVAFESELMANKGRVAAV 2673
Score = 262 bits (670), Expect = 8e-68
Identities = 301/1511 (19%), Positives = 598/1511 (38%), Gaps = 48/1511 (3%)
Frame = +1
Query: 1792 TIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG 1971
++++R + + Y EL +LA R LED RL F+ + + E IK++E++L D
Sbjct: 865 SVEKRQKKINETYSELQELALRRHALLEDAIRLYGFYRECDDFEKWIKDKEKML-RIDDP 923
Query: 1972 RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQ------DESIPGS----DNIPP 2121
RD N E R EK+L L SGK ++ DE + D +
Sbjct: 924 RD------------NVETAKRKYEKFLTDLSASGKRVEAIDAAVDEFVRQGHSQLDKVKA 971
Query: 2122 RLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEG 2301
R I + L L +++ L G F D+ ++ + + + + ++G D
Sbjct: 972 RQRHIHQLWDHLNWLKTQKEKSLEGASSVELFNRTCDEAHDWMLEKITQLDTAELGPDLK 1031
Query: 2302 TVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQE-AREHPDIRQRLDTTLKQKAELEN 2478
TVQ L ++H + EL ++ ++ ++ A S+ E ++ R + + +++
Sbjct: 1032 TVQALQRRHQHLERELAPVEEKVRKVNLLANSVKSSYPHELNNVNARQNEIKELWNQVQT 1091
Query: 2479 LSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQ 2658
++ R+ RL DA+ + + ++ +W + + + P RD+ E ++ L +
Sbjct: 1092 KAKERRSRLEDAVGQQIFMNSSKNLINWAVDIQETMKVEEPVRDVATAEQLRKHHIELGE 1151
Query: 2659 DMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHR 2838
D++ +E + V +L QLL +P D+ R +KL+ + + K L++
Sbjct: 1152 DIRTREDEFREVEELGNQLLR-RNPTLVDVSERLDKLHGLYQAVTSDWIAKEAWLQQCLD 1210
Query: 2839 LETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLH 3018
L+ F + + LE +D L L V L ++ E L A +L +
Sbjct: 1211 LQQFNREADQIEATTSSHEAFLEFTD-LGESLDDVEALLKQHEKFENTLHAQDDRLKAFS 1269
Query: 3019 KEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQA 3198
AD + + + I + ++ + + + A L + Q+F ++D +
Sbjct: 1270 DTADKLIAQNHYDKDYINDRRNQVLARRNQVKDAAQRRRAALKASEHYQQFSAEVDDLRD 1329
Query: 3199 WLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQ 3378
WL + + AS+E + L E+ L +H A E+ + + G + ++ + +
Sbjct: 1330 WL-GDKMKTASDESYRDLNNLERKLQKHEAFERELRANEGQLRAVNKAGKALISEE-NYR 1387
Query: 3379 YMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDD 3558
+ + L L + W +L + + L Q + R + A + L + EN L
Sbjct: 1388 SDDVGETLKELNDQWNQLVDLSLEKGRRLRQAACQHGYNRTMEDARLKLEEIENCLQSKQ 1447
Query: 3559 IPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAA-----------DK 3705
+ L + LK+HQ + M ++K+ + + G+++ +GH+ A K
Sbjct: 1448 VGVDLRSCKELLKKHQTLESDMCQWEQKVDDLVVMGEEMAHEGHFDALGLLEEYWVSRGK 1507
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKM-IRAQDETYR 3882
I + +DE +EKA E K L+ +L Q+F + E+ W+ EK + + + R
Sbjct: 1508 IRELCDVLDEAWRGLQEKAAERNKDLELSLKAQEFFFEAGEVESWLNEKNDVLSSTDYGR 1567
Query: 3883 DAKTITSKFVRHQAFQSELAANKERLDQLKH-AAINLGDDKPEYHGTIDPQIEELATQWD 4059
D T +H+A + EL + ++ H AAI + P+ + Q + +A Q
Sbjct: 1568 DRDAATKLLTKHKAVELELDTYNGIVTEMGHTAAIMINAKHPDSKAIANKQ-QAIAQQMR 1626
Query: 4060 ELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK-- 4233
L++ + Q+L ++ + Y ++++W + E ED D + + K
Sbjct: 1627 ALQRLATVRQQRLMESMYRHEYFLESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFN 1686
Query: 4234 --QHLIET---------EMIKK-----AQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQ 4365
+H IE E+ +K + +I D + ++ ++
Sbjct: 1687 DFKHRIEAGSERFNQCEELARKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIK 1746
Query: 4366 EQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQ 4545
E + L + +R + L+ +F RDV + I E+ A ++LG L L
Sbjct: 1747 ESWKHLLGLIRNREQRLQAAGEIHRFHRDVAEALSRIQEK-EAALPEDLGRDLNSVLALI 1805
Query: 4546 KNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSA-WQELKEAVKDR 4722
+ + N++ E + + + L N + Q++ A W+ELKE R
Sbjct: 1806 RRHEGFENDLVALEAQLQVLVEDASRLQAHYPGNNAVHIDQQQQIVVAHWEELKERSALR 1865
Query: 4723 KGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKF 4902
+ L S +FL + W + M +++ +D S + +HE L+ +I+
Sbjct: 1866 RDQLQASCDLQRFLTQVRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAR 1925
Query: 4903 ADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALH 5082
D+ ++ V+ +++ + Q+ L +
Sbjct: 1926 EDSFSSVLDLGEAMVQTGHYAALEVEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFL 1985
Query: 5083 REIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDT 5262
R+ L +E G E V ++ +F + E++ + D
Sbjct: 1986 RDAKQLDNLSTTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVT-QEEKLTALQEHGDK 2044
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
L+ H D+PTIA + + + L D R + LEA L +F D + S I EK
Sbjct: 2045 LLAQNHFDSPTIARRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEK 2104
Query: 5443 THAMPDDL--GRDSSSVGALSR--KHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKAL 5610
+ + G SS + + KHQ + ++AA ++ +I+ L +
Sbjct: 2105 QKKLEAEASKGEVSSLEDKIKKLQKHQAFQAELAANQSRIEEIKTKGERLLQ-QKHPASA 2163
Query: 5611 DIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERP 5790
+I + + +WR L R L + D+ +F N V + W+ + + + + +
Sbjct: 2164 EIRQQLEHLHASWRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTG 2223
Query: 5791 KDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNR-KHYASSEIEKKLIKLTTER 5967
KD L + +++ + +L L+ + + S I+++ +
Sbjct: 2224 KDYEHCLSLQRKLDDVDSDMRVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKW 2283
Query: 5968 AEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKH 6147
+ E L LE++ F RD + + + + + G++L L +K
Sbjct: 2284 KGLQGALSTYREMLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQ 2343
Query: 6148 EAFEKSAFAQE 6180
EA E+ A E
Sbjct: 2344 EAMERDMTAIE 2354
Score = 256 bits (655), Expect = 4e-66
Identities = 305/1645 (18%), Positives = 648/1645 (38%), Gaps = 39/1645 (2%)
Frame = +1
Query: 1642 DVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQ 1821
+VE +K+ +D++ G+RV A F G+ ++ + R +
Sbjct: 926 NVETAKRKYEKFLTDLSASGKRVEAIDAAVDEFVR------QGHSQLDK--VKARQRHIH 977
Query: 1822 KRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLL 2001
+ + L L ++++ LE + F E + E+ L + + G D+ TV L
Sbjct: 978 QLWDHLNWLKTQKEKSLEGASSVELFNRTCDEAHDWMLEKITQLDTAELGPDLKTVQALQ 1037
Query: 2002 AKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRK 2181
+H++ E L +E+ + ++++ ++ +N+ R EI++ N+++ + R+
Sbjct: 1038 RRHQHLERELAPVEEKVRKVNLLANSVKSSYPHELNNVNARQNEIKELWNQVQTKAKERR 1097
Query: 2182 ERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFD 2361
RL V F + ++ + D M E+ +D T + L K H ++ ++++ +
Sbjct: 1098 SRLEDAVGQQIFMNSSKNLINWAVDIQETMKVEEPVRDVATAEQLRKHHIELGEDIRTRE 1157
Query: 2362 QHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSD 2541
+ + L + D+ +RLD + + ++ L L L + +
Sbjct: 1158 DEFREVEELGNQLLRRNPTLVDVSERLDKLHGLYQAVTSDWIAKEAWLQQCLDLQQFNRE 1217
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLN 2721
AD +E+ L G +++VE + + + E + Q+ ++ +D A +L+
Sbjct: 1218 ADQIEATTSSHEAFLEFTDLGESLDDVEALLKQHEKFENTLHAQDDRLKAFSDTADKLIA 1277
Query: 2722 VEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRV 2901
H + D I R+N++ AR Q++D ++R L+ + + F + + W+ DK +
Sbjct: 1278 QNHYDKDYINDRRNQVLARRNQVKDAAQRRRAALKASEHYQQFSAEVDDLRDWLGDKMKT 1337
Query: 2902 LEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDI 3081
SD DL+ + + ++ ER+L A + +L +++K + E + + E +
Sbjct: 1338 A--SDESYRDLNNLERKLQKHEAFERELRANEGQLRAVNKAGKALISEENYRSDDVGETL 1395
Query: 3082 KRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEA 3261
K ++ W+ L E +L +A + R ++ + L + + S++ L
Sbjct: 1396 KELNDQWNQLVDLSLEKGRRLRQAACQHGYNRTMEDARLKLEEIENCLQSKQVGVDLRSC 1455
Query: 3262 EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD-QTDPQYMF---------LRQRLAGL 3411
++LL +H + ++ + + + MG+ + + D + +R+ L
Sbjct: 1456 KELLKKHQTLESDMCQWEQKVDDLVVMGEEMAHEGHFDALGLLEEYWVSRGKIRELCDVL 1515
Query: 3412 QEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQ 3591
E W LQ R L L Q F +A + E L+++ + L+ D + + A
Sbjct: 1516 DEAWRGLQEKAAERNKDLELSLKAQEFFFEAGEVESWLNEKNDVLSSTDYGRDRDAATKL 1575
Query: 3592 LKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEV 3771
L +H+ +D + + +G + H + I K + I ++ A + A
Sbjct: 1576 LTKHKAVELELDTYNGIVTEMGHTAAIMINAKHPDSKAIANKQQAIAQQMRALQRLATVR 1635
Query: 3772 LKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAAN 3948
++L +++ ++ + EL +WI+E+ A E Y +D + + + F+ + A
Sbjct: 1636 QQRLMESMYRHEYFLESRELEQWIKEQEQAAASEDYGQDYEHLLILQAKFNDFKHRIEAG 1695
Query: 3949 KERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDA------- 4107
ER +Q + A L ++ Y I+ + E+L D+ + + + + ++
Sbjct: 1696 SERFNQCEELARKLIANESPYIQDIEKRQEQLGQDDDDPVRQVQRQHDLIKESWKHLLGL 1755
Query: 4108 --NRQQLYVQSIADMKEWATQLENEMTR---------EDQPGDLTTVNVAMQKQHLIETE 4254
NR+Q +Q+ ++ + + ++R ED DL +V +++ E +
Sbjct: 1756 IRNREQ-RLQAAGEIHRFHRDVAEALSRIQEKEAALPEDLGRDLNSVLALIRRHEGFEND 1814
Query: 4255 MIKKAQHIDXXXXXXXXXXXXHP-DELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
++ + +P + +I + V + L+ RR L+
Sbjct: 1815 LVALEAQLQVLVEDASRLQAHYPGNNAVHIDQQQQIVVAHWEELKERSALRRDQLQASCD 1874
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
+F V D W + ++ L+ + L EI+ E + + +
Sbjct: 1875 LQRFLTQVRDLMNWAAGLRAAMSTEDKVRDAASAQILKAEHEALKGEIEAREDSFSSVLD 1934
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
G+ ++ GH E+K +L Q+L A + +K L + H FL D + +
Sbjct: 1935 LGEAMVQTGHYAALEVEEKCNQLLDERQKLHSAWQQKKVHLDQLIDLHFFLRDAKQLDNL 1994
Query: 4792 MSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTE 4971
+ QE + D G Q+KKH + + + + AL K + + +
Sbjct: 1995 STTQEAALSGDNFGDSVEEVDAQVKKHNEFEKLLVTQEEKLTALQEHGDKLLAQNHFDSP 2054
Query: 4972 QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADK----EVVAGS 5139
I R +++ + A +++ R++ + WI +K E A
Sbjct: 2055 TIARRLSEVVQRRARIRNLCDARRRRLEAGLLHAQFVRDVAEAESWIGEKQKKLEAEASK 2114
Query: 5140 QENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSL 5319
E + ++ LQ + Q F + R+ + L+ H + I + L
Sbjct: 2115 GEVSSLEDKIKKLQ-KHQAFQAELA-ANQSRIEEIKTKGERLLQQKHPASAEIRQQLEHL 2172
Query: 5320 NEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK-THAMPDDLGRDSSSVGAL 5496
+ +W LL R + LE ++ + +F + + I +K D G+D +L
Sbjct: 2173 HASWRKLLLESGNRGRGLEEAQDILEFNNQVEKIEAWIRDKEMMVQAGDTGKDYEHCLSL 2232
Query: 5497 SRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDA 5676
RK + D+ ++ I A +L +++ I R W+ L+G
Sbjct: 2233 QRKLDDVDSDMRVDDSRIKTINALADKLIKQGRDNESKAIQQRRDSFNNKWKGLQGALST 2292
Query: 5677 RTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDA 5856
L ++ F + D + E MN+ + KD+ VE L ++++ ++ A
Sbjct: 2293 YREMLAGALEIHLFNRDIDDTSQRVIEKSVAMNTTDIGKDLPAVEHLQRKQEAMERDMTA 2352
Query: 5857 REENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
E + R+L + + +I L +L + ++ R + R E L +++F
Sbjct: 2353 IEGKLKEHKAEARELSLKYPDKAPQINGILSELQSNWDDLQRFTQHRREALNQAYTLHKF 2412
Query: 6037 ARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL----EK 6204
D E W+ + E + E L++ H+ + +++ F AL +K
Sbjct: 2413 QADLHELELWVADTIKRMDESEPPTTISEAEALLELHQERKAEIDGRQDTFKALKEHGQK 2472
Query: 6205 LTTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKH 6384
L T + E R+G A+ R + A Q +++ L K
Sbjct: 2473 LLTINEDVKDNLEHLEKLRQGLANAWETKRQKLTQAHQLQLFKEQADQADSW---LATKE 2529
Query: 6385 TYESLDRKAANRSWEKLYAVLRQNE 6459
+ L+ S + A+LR++E
Sbjct: 2530 AF--LNNDDLGESLSGVEALLRKHE 2552
>gi|39592126|emb|CAE75346.1| Hypothetical protein CBG23326
[Caenorhabditis briggsae]
Length = 4061
Score = 883 bits (2282), Expect = 0.0
Identities = 617/2204 (27%), Positives = 1031/2204 (45%), Gaps = 136/2204 (6%)
Frame = +1
Query: 46 DYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKML 222
D D+ N+ FERSRI+ L DER +QKKTFTKW NS L R S ++ DL+ D+ DG +L
Sbjct: 23 DQDEFNNETLYFERSRIRTLQDERVHIQKKTFTKWCNSFLNRASLEIVDLFEDVGDGILL 82
Query: 223 LRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLG 402
++LL ++SG++L KP G+MR+ +EN+ K L FL+ + + LEN+G+ DI+D N RL LG
Sbjct: 83 MKLLEIISGDKLGKPNRGRMRVQKVENLNKVLDFLKKKKIQLENIGAEDILDRNERLILG 142
Query: 403 LIWTIILRFQIQDITFEDADNH-ETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
LIWTIILRFQI I ED + E + AK+ALLLWCQ KTAGYPNV ++NF+TSWR+GLA
Sbjct: 143 LIWTIILRFQIDTIVIEDEEERGERKHAKDALLLWCQRKTAGYPNVRIENFTTSWRNGLA 202
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIH HRPDLVD++ L + + NL AFD AE +L +A+ LDAEDV+V +PDEKSII
Sbjct: 203 FNALIHSHRPDLVDFNRLNPNEHVDNLNHAFDVAEKKLEIARLLDAEDVDVTRPDEKSII 262
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYV YYH+F K K + +RI ++ +LM ++ M + YE ++S+LL WI I+ L
Sbjct: 263 TYVSLYYHHFAKQKTEMTGARRIANIVGKLMVSETMEDDYEHIASELLNWIRITIKTLES 322
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVP---- 1107
R F N+L G++ + +FN +RT EKPPK+ EKGELE L FT+Q+ +A +++ + P
Sbjct: 323 RRFPNSLNGMRDEHAKFNQFRTSEKPPKYKEKGELEALFFTIQTKRKAMSRKQYQPPQGL 382
Query: 1108 ------------------REGKLIADINR-------------------AWQS-----LEK 1161
R+ +IA++ R +W LE+
Sbjct: 383 FMHDIESAWAQLDYAENERQVSIIAELQRQEKLEQLAQRFHKKAKLRDSWLKSVQVVLEE 442
Query: 1162 AEHER-----ELVLKEE-------LIRQEKLEQLAARFNR---------------KAEMR 1260
EH R E LK++ L R+++ + L A N + E+
Sbjct: 443 MEHGRSASQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESEKIRGMEREII 502
Query: 1261 ETW------LTENQRLVSQ-----------DNFGNDLSSVEAATK--------------- 1344
+ W L + +R + D N+L S+E A +
Sbjct: 503 DRWTQLLALLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLL 562
Query: 1345 -KHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARR 1521
KH+ ++ I A+ + + + V +RR
Sbjct: 563 GKHDLVDAQINAHGSLLSKLSQAANNYIRHKEEQFDVLQRKLDEVTSQYNTLVELCRSRR 622
Query: 1522 VRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIG 1701
+ LE + ++ + E+ A L + E L AL DI+ +
Sbjct: 623 LALERARSLFQFIQDH----------------EEEMAWLAEKEKLCTT-ALNSGDISAVP 665
Query: 1702 ERV----NNSIAQAQRFRNPDGPDGSGYKPVEPGT----IDERSDVLQKRYKELLDLAAE 1857
+ N + + G G + V+ G I R + + ++ L
Sbjct: 666 QTTLLYKNVEMEMQTHWARSKGMIAGGERLVQSGQSKEDIQRRLTQMNQGWERLRVAVDA 725
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
L + + Q++ DV E E I+E+ ++ S D GRD LL +H E +R
Sbjct: 726 LGNWLSEARHAQQYFQDVNEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRA 785
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
+ + RL+ +L + + A + + +E++ + E
Sbjct: 786 YKNDITRLEEMQSQLANSAF--------HTATTSQSVQETEEVTVPQIEMAY-------- 829
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLK--KHDDVHDELQNFDQHIKVLHAKA 2391
+Y + +RV E + E + + K D + + KV+ ++
Sbjct: 830 --------KYEGNGMRVAKGEVLALLEKSTPEWWRALKRDGTEGYVPA--NYCKVVPGES 879
Query: 2392 ESLPQEAREHPD-----------IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYS 2538
++ Q ++ + +R EL L+ +R++ L D + L + Y
Sbjct: 880 VTVTQTTQKTTTTVEGNETKSSVVAERQHKISNDYRELRRLADVRRRLLSDNIKLLRFYR 939
Query: 2539 DADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMK-NQEAKVTNVNDLARQL 2715
+ D E W + + L P E V + +FD LE DMK N ++ ++ND+A L
Sbjct: 940 ECDDFERWKEIEVSLADEPSP----EHVTAFRRKFDKLEADMKTNGGTQLKHINDIANDL 995
Query: 2716 LNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKT 2895
++ H S I +RQ+K+NA W L + Q+ LE R+ F C+ W+ K
Sbjct: 996 ISEGHGQSRQIENRQHKINAMWENLERLRKQRAVRLEATERVADFDTTCESAREWMLGK- 1054
Query: 2896 RVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIRE 3075
E D ND+ + L ERDL ++ K+ +L K A ++++ P+EA AI
Sbjct: 1055 --FEQLDRNPNDVKSLQNL-------ERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIER 1105
Query: 3076 DIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLA 3255
I + + L ++ +E +++ + F L +W+ T++ + + P +A
Sbjct: 1106 KIAELRTLHADLLRRAQEKMLLAEQSQGKEMFESALRDMMSWIEKTRKGMMEDVHPVDVA 1165
Query: 3256 EAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQ 3435
EAE+LL +H + E+I + + + +G R+ + P+ + ++L L L+
Sbjct: 1166 EAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLE--RSPRMPKVEEQLQALVSEMAALR 1223
Query: 3436 RMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFI 3615
++ R +L Q L+LQ+F R++++ + E +L D++ S+E EN LKRH+D
Sbjct: 1224 DLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLE 1283
Query: 3616 TTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDAL 3795
+DA + ++ A D + + H + I ++ R++ RR A R A + K+L+ +L
Sbjct: 1284 AKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASL 1343
Query: 3796 SLQQFLSDCDELREWIEEK--MIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL 3969
Q+ + DE+ W+ EK ++ + D+ I + ++H+AF++E+ AN+ R+ Q+
Sbjct: 1344 EYQEMRREADEVMGWMHEKAKLVASGDDAALAPSAIPHRLLKHEAFEAEIIANESRIQQI 1403
Query: 3970 KHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK 4149
NL ++ + ++ QW +L+K KGQ+L A Q+ + + D
Sbjct: 1404 NREGDNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNKGQRLRQAADQKGLDRILEDAH 1463
Query: 4150 EWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHI-DXXXXXXXXXXXXHPD 4326
++E+ + +DQ DL +V +QK ++E EM + D H D
Sbjct: 1464 AKLDEMESALNSKDQGLDLRSVKDLLQKHTVLEQEMGLYGNKLADIENRGKKMAVEGHYD 1523
Query: 4327 ELENIKAHRLAVQEQLQR---LQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLA 4497
K H + V + L+R ++ P R+ L+ + Q DVD E WI+E+ +A
Sbjct: 1524 A---DKIH-MTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIA 1579
Query: 4498 KAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQE 4677
+Q+ G +L + + K + L E++ H I+++ +L+ H + K E
Sbjct: 1580 SSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLGQASKLVKRHHPASSQIKAKSGE 1639
Query: 4678 LRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKN 4857
L SAW EL+ ++ R+ + K Q+L+D E E+WM+E+ + ++ G DE + +
Sbjct: 1640 LESAWSELRRLLRSRRAIVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARK 1699
Query: 4858 QIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXX 5037
+ KH L D+ + + L K + V+ P ++ Q RQ ++ + L
Sbjct: 1700 LLAKHRALCEDMTTYRQWLEKLDVKCSELVQSDRPHVDRFQKRQDELVHEFDSLSKLAED 1759
Query: 5038 XXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTEN 5217
Y RE DL QWI ++ A ++ +DYEH++ LQ +F +F + +
Sbjct: 1760 RRNALEDAVCLYEYMRESADLEQWIGEQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKT 1819
Query: 5218 IGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHK 5397
GSER + +T++ A + ++ L AW L E ++TR L + LH+
Sbjct: 1820 -GSERFTSCETAANTILRRNPPFARDVVKKQEKLRSAWNLLCEYIETRTAKLAVAEELHR 1878
Query: 5398 FYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAE 5577
F+ D + + +K MP DLGRD V +L ++H+ K+ ++ ++ +A
Sbjct: 1879 FHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQQHEALDKETHNAQPRLTKLVEEAER 1938
Query: 5578 LRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDE 5757
L+ Y G A IG R+ +V+ W LR D R L DL F VRDLL W D
Sbjct: 1939 LKKAYPGGNAEQIGGRQQTLVEEWEELRNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDL 1998
Query: 5758 VKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIE 5937
++ S + D+ E L H L E+DARE F +S G ++N +HYA+ EI+
Sbjct: 1999 TISDIQSDLQINDLQQAEWLQTEHSRLSHEMDAREPEFTRLVSDGEKMVNAQHYATEEIK 2058
Query: 5938 KKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNL 6117
K L T + W R YL ++ + F R+A + + ++ L S G ++
Sbjct: 2059 NKTRLLKTALERLRSEWTLRNGYLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSV 2118
Query: 6118 EETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEE 6249
+ K+ + FEK+ +ER L+ T EL +++H E +
Sbjct: 2119 ADVESQKKRLDTFEKALSTLDERTATLDH-TANELVKSRHMESK 2161
Score = 496 bits (1276), Expect = e-138
Identities = 455/2060 (22%), Positives = 852/2060 (41%), Gaps = 122/2060 (5%)
Frame = +1
Query: 850 MENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFD 1029
+E+ + Y S+DL +WI ++Q F + E ++ ++F++++ K +
Sbjct: 1764 LEDAVCLYEYMRESADLEQWIGEQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKTGS-E 1822
Query: 1030 EKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHER--ELVLKEELI 1203
E T+ +R N PF K + AW L + R +L + EEL
Sbjct: 1823 RFTSCETAANTI---LRRNP--PFARDVVKKQEKLRSAWNLLCEYIETRTAKLAVAEEL- 1876
Query: 1204 RQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYE 1383
RF+R + E W+ + + +D G D+ V + ++HEA++ + +
Sbjct: 1877 ---------HRFHRDVDEFEQWMADKMANMPRD-LGRDVKHVHSLWQQHEALDKETHNAQ 1926
Query: 1384 ERXXXXXXXXXXXXXXNYHDQAK-INERKENVXXXXXXXXXXXXARRVRLELSMAIQ--- 1551
R A+ I R++ + R+ L + +
Sbjct: 1927 PRLTKLVEEAERLKKAYPGGNAEQIGGRQQTLVEEWEELRNATDDRKDMLRAAFDLHTFN 1986
Query: 1552 -KIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQ 1728
K+ I+S L DL E L +H+ L +++ ++
Sbjct: 1987 GKVRDLLAWTDLTISDIQSDLQINDL----QQAEWLQTEHSRLSHEMDAREPEFTRLVSD 2042
Query: 1729 AQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWD 1908
++ N Y E I ++ +L+ + L R L + F +
Sbjct: 2043 GEKMVN-----AQHYATEE---IKNKTRLLKTALERLRSEWTLRNGYLSQAVQWHAFQRE 2094
Query: 1909 VAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQD 2088
++ I + L S G + V + E L L++ LD + EL
Sbjct: 2095 AKQIIASIGSKRTTLRSLAVGGSVADVESQKKRLDTFEKALSTLDERTATLDHTANELVK 2154
Query: 2089 ESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTL-- 2262
S NI +++ + + L+E +R L F +D ++ ++ +
Sbjct: 2155 SRHMESKNIAMWQSKVHEELKLLREDIEARHVMLKDAFALASFGSDVAQIEAWIDEKTNG 2214
Query: 2263 ----RVMSSEDVGKDEGTVQLLLKK--------HDDVHDELQNFDQHIKVLHAKAESLPQ 2406
R SSE + +E +L + + + D++ + Q +K LH ++
Sbjct: 2215 IRKARDQSSESISIEEKMKRLQTHQALEAEVAANKTIVDQILHRGQQLKSLHRNSK---- 2270
Query: 2407 EAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLL 2586
I + + ++L + + L +A L + ++V +WI+EK L+
Sbjct: 2271 -------IGDTCNELNVKWSQLAGACDDQSRALEEARDLLRFKQLVENVLTWINEKEVLV 2323
Query: 2587 ATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNK 2766
+T GRD+E ++ R D D E + +N L +L+ + D + Q +
Sbjct: 2324 STADMGRDMEHCRMLLERLDGTRSDSTVDEQTLDEINRLGEKLVKQGRTSRDQVQKEQQR 2383
Query: 2767 LNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVM 2946
LN +W L + R EL A + TF D ++T I +K ++ SD D + V
Sbjct: 2384 LNEKWRLLLGQLSHYRTELVAAMEVHTFNRDVEDTDERIHEKIAAMK-SDDFGKDFASVE 2442
Query: 2947 KLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVR 3126
L R+ S +ERD+ AI KL S K+A I +RP ++I + +K++ + W L++
Sbjct: 2443 LLVRKQSALERDMSAIHQKLISHDKDAQKILEKRPPLKESILDSLKKLEESWKKLSEAAE 2502
Query: 3127 EHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEID 3306
KL+ + L ++L D+ + W + ++ S + P+ + A +LL QH + EID
Sbjct: 2503 LRNDKLNRSFKLYKYLDDVKKTEQWANQVRNKMTSHQTPKDSSGARKLLEQHHERKAEID 2562
Query: 3307 GYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRL-AGLQEGWEELQRMWDNRQHLLSQGLNL 3483
G A++ +++ G + Q+Q P++ QR +Q +L++ W++ + L + L
Sbjct: 2563 GRADELRQLHEEGQALNQEQ--PEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEW 2620
Query: 3484 QMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMF 3663
++ +A Q E L+ +EN +++ ++ + + E +K H F T+ EKI +
Sbjct: 2621 MLWCDEAVQCEQWLADKENQVSRGELGDTSDAVEMLIKGHSAFEETVRKQSEKIDVLVKN 2680
Query: 3664 GDQLCQDGH-YAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREW 3840
D L G+ Y AD I +K + R + + L+D+ +F+ C EL W
Sbjct: 2681 ADALVSGGNNYRADIITRKDE-VTARHDLLLKSMSKRKDMLEDSKRYHEFIRHCGELIIW 2739
Query: 3841 IEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGT 4020
I K+ A DE++ D + SK +H AF SEL N++RL ++ L D
Sbjct: 2740 ITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELVENEKRLSNVERQGEELVADNHFMSEQ 2799
Query: 4021 IDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPG 4200
+ Q+ EL + WDEL + K Q+L +A + + D+++W ++E E+ ED
Sbjct: 2800 VKAQLVELRSGWDELRTKSALKTQRLREAFELHSLQRKVEDLEKWLDKVEGELASEDHGR 2859
Query: 4201 DLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQR 4380
D+ + + ++K ++TE+ ++ + ++ V+ +
Sbjct: 2860 DMLSTELLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSG 2919
Query: 4381 LQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQL 4560
L P+ RR+ L +A F++ + +++ W+S+++ LA + G+SL LQK
Sbjct: 2920 LDEPVQIRRENLVDAQAFFEWVKAAEEDLEWLSDKMPLASSGESGDSLQSALSLQKKHAA 2979
Query: 4561 LSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGE 4740
L E++ + ++ G+++I + H +K + L +A LKE+ R+ L E
Sbjct: 2980 LEKELETRQSAMDDTEKRGKDMIRQRHFASGHIQKILDRLSTAMLTLKESCGLRRDLLQE 3039
Query: 4741 SEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRA 4920
+ AH++ + EAE W+ EQ M E G+D+ ++ +++ L +++ F + I
Sbjct: 3040 AIDAHEYYTEETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDR 3099
Query: 4921 LATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDL 5100
L +A + + I +Q ++E L+ L + R+ DDL
Sbjct: 3100 LKKRADGLLAREHHDAMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDL 3159
Query: 5101 LQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGH 5280
W+ +KE A +++ GQD E Q + E+F+ R+ G ERVA + L+ GH
Sbjct: 3160 SDWLREKERTASAEDYGQDLEDCQQIIEQFESTVRELAAAG-ERVALVQRSQEDLLRSGH 3218
Query: 5281 TDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHA--- 5451
+I + W ++ E+ + R Q L +R +H+F + L+ + +K
Sbjct: 3219 PYGASITAKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQTLNWLQDKEATGVA 3278
Query: 5452 -MPDDLGR-DSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSR 5625
+DL R D +SV A ++H ++ + A+ +QVA++ +A L + + D + R
Sbjct: 3279 MEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWNSFP-DTRHHLEVR 3337
Query: 5626 ESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSG 5805
++ + + + RL L + R+++ WM ++ M S++ P+DV+
Sbjct: 3338 RLDMEEQLKDILEAAKKHLERLRHMQSLQSYFQEYREMMQWMKNMQTTMTSEQLPRDVAS 3397
Query: 5806 VELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKK----------LIKL 5955
E L+ H E+ R+ + GR ++ H S EI++K L ++
Sbjct: 3398 CESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVEVLEKSWEMLCEI 3457
Query: 5956 TTERAEM------MRRWEDRWEYLQLILEV--------YQFARDAAVAESWLFAQEPYLI 6093
+RAE+ +++W+ E L LE ++ +AES L + +L+
Sbjct: 3458 WKDRAELYEENMDVQKWKQNAEQLDSWLEERAGLLGDDWRMVDSVEMAESHLRDFDDFLV 3517
Query: 6094 --------------------------SKEYGR--------NLEETIKLIKKHEAFEKSAF 6171
SKE R +TIK+++K
Sbjct: 3518 TLEAQNEKCEMVKRLTLVEQNFSRLRSKEIDRAKIAEEDQKRRDTIKIVEKGNILANRRQ 3577
Query: 6172 AQEERFLALEKLT------------TFELKETQHREEETAKRR----------------G 6267
+E R L T KE + R + TA
Sbjct: 3578 ERERRKTQEISLLRPSPSGEEFSTHTMPRKERKDRAKTTADLAPGSIQIGDILATSSTVA 3637
Query: 6268 PAHIGSPSRSTPAAETSFGAQDDGAKQGEAFE--------GTLIRKHTYESLDRKAANRS 6423
P G TP+ T + ++G +E G RK +S ++A RS
Sbjct: 3638 PLQSGVEMTKTPSFTTR---RPQSIRKGSRWEDMGAIDMKGFFDRKQCQQSGGKRATIRS 3694
Query: 6424 WEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGA 6603
W+ Y +L L F+KD + E+V PP+ + G +Y K+KN L + G+
Sbjct: 3695 WKNYYGILCGQLLCFFKDEQQFIENVAAAPPVYIYGAQCEQYPEYAKRKNAFRLLIQDGS 3754
Query: 6604 EYLFQCGSEEDMQRWLTELQ 6663
E++F C E M W+ +++
Sbjct: 3755 EFMFSCPDERQMLEWVAKIK 3774
Score = 353 bits (905), Expect = 4e-95
Identities = 380/1867 (20%), Positives = 751/1867 (39%), Gaps = 33/1867 (1%)
Frame = +1
Query: 703 KFLDAEDVNVDQPDEKSIITY---------VVTYYHYFNKLKQDNIQGKRIGKVINELME 855
K + E V V Q +K+ T V H K+ D + +R+ V L+
Sbjct: 873 KVVPGESVTVTQTTQKTTTTVEGNETKSSVVAERQH---KISNDYRELRRLADVRRRLLS 929
Query: 856 NDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEK 1035
++ + R+ D W ++ L +E E+ V +F+ K +
Sbjct: 930 DNIKLLRFYRECDDFERWKEIEVSLADEPSPEH----VTAFRRKFDKLEADMKTNGGTQL 985
Query: 1036 GELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEK 1215
+ + L S + R R+ K IN W++LE+ K+ +R E
Sbjct: 986 KHINDIANDLISEGHGQS-RQIENRQHK----INAMWENLERLR-------KQRAVRLEA 1033
Query: 1216 LEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXX 1395
E++A F+ E W+ + D ND+ S++ + + +E I A E+
Sbjct: 1034 TERVAD-FDTTCESAREWMLG--KFEQLDRNPNDVKSLQNLERDLKPLEDKIAALEK--- 1087
Query: 1396 XXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXX 1575
++ ++A ERK ++ L +++F
Sbjct: 1088 -----LAAAVKKDHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQGKEMFESALR 1142
Query: 1576 XXXXXXXIKSRLLSEDLGAHLMDV---EDLLQKHALLESDINIIGERVNNSIAQAQRF-- 1740
+ + ED+ H +DV E+LL+KH L I V +R
Sbjct: 1143 DMMSWIEKTRKGMMEDV--HPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLE 1200
Query: 1741 RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAEL 1920
R+P P ++E+ L L DL R L+ L F + +
Sbjct: 1201 RSPRMPK-----------VEEQLQALVSEMAALRDLYRRRDTILKQQLDLQLFNRESERI 1249
Query: 1921 EHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIP 2100
+ K E L + G + +V +LL +H++ E L E L+ + ++
Sbjct: 1250 DAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHA 1309
Query: 2101 GSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSS- 2277
S I R ++ ++ +A RK++L +EY + +AD+V ++++ ++++S
Sbjct: 1310 DSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASG 1369
Query: 2278 EDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHPDIRQRLDTTL 2454
+D + L KH+ E+ + I+ ++ + ++L + E P++ + +
Sbjct: 1370 DDAALAPSAIPHRLLKHEAFEAEIIANESRIQQINREGDNLVGKNHYESPNVEKVVRQVN 1429
Query: 2455 KQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMK 2634
Q +L+ + QRL A L + + +DE L + G D+ V+ +
Sbjct: 1430 AQWGDLKKQVYNKGQRLRQAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDLL 1489
Query: 2635 HRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKR 2814
+ LEQ+M K+ ++ + +++ H ++D I L R+A ++ +++
Sbjct: 1490 QKHTVLEQEMGLYGNKLADIENRGKKMAVEGHYDADKIHMTVGDLLKRYAAMKGPAQRRK 1549
Query: 2815 NELERA---HRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDL 2985
+L+ + H+L F +DC+ + WI +K + D L+ + + ++ +E ++
Sbjct: 1550 GDLDESRLWHQL-VFDVDCE--LQWIAEKKPIASSQDC-GRTLTEALNMVKKQEQLEAEV 1605
Query: 2986 GAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQ 3165
++D + +A + + + I+ + W L + +R A +D Q
Sbjct: 1606 NQHGGQIDKVLGQASKLVKRHHPASSQIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQ 1665
Query: 3166 RFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG 3345
++L D ++W+ + +ASE+ A +LL +H A+ E++ Y + +K+
Sbjct: 1666 QYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKC 1725
Query: 3346 DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
+ Q P ++R L ++ L ++ ++R++ L + L ++R++ E +
Sbjct: 1726 SELVQSDR-PHVDRFQKRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWI 1784
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
+Q +D + E + + +F ++ E+ + + + + A
Sbjct: 1785 GEQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKTGSERFTSCETAANTILRRNPPFARD 1844
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
+ KK + E + KL A L +F D DE +W+ +KM + RD
Sbjct: 1845 VVKKQEKLRSAWNLLCEYIETRTAKLAVAEELHRFHRDVDEFEQWMADKMANMPRDLGRD 1904
Query: 3886 AKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQI----EELATQ 4053
K + S + +H+A E + RL +L A L K Y G QI + L +
Sbjct: 1905 VKHVHSLWQQHEALDKETHNAQPRLTKLVEEAERL---KKAYPGGNAEQIGGRQQTLVEE 1961
Query: 4054 WDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK 4233
W+EL T+++ L A + + D+ W +++ + Q DL +
Sbjct: 1962 WEELRNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLQINDLQQAEWLQTE 2021
Query: 4234 QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKA 4413
+ EM + E IK ++ L+RL++ R
Sbjct: 2022 HSRLSHEMDAREPEFTRLVSDGEKMVNAQHYATEEIKNKTRLLKTALERLRSEWTLRNGY 2081
Query: 4414 LERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPW 4593
L + F R+ I + ++ +G S+ D +K L + +
Sbjct: 2082 LSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQKKRLDTFEKALSTLDER 2141
Query: 4594 INQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDC 4773
+ + EL+ H ++ + L+E ++ R L ++ F D
Sbjct: 2142 TATLDHTANELVKSRHMESKNIAMWQSKVHEELKLLREDIEARHVMLKDAFALASFGSDV 2201
Query: 4774 GEAEAWMSEQELYMMQD-ERGKDEFSTKNQIKK---HERLQSDIDKFADTIRALATKAH- 4938
+ EAW+ E+ + + ++ + S + ++K+ H+ L++++ + + +
Sbjct: 2202 AQIEAWIDEKTNGIRKARDQSSESISIEEKMKRLQTHQALEAEVAANKTIVDQILHRGQQ 2261
Query: 4939 -KFVEEKSPLTE---QIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQ 5106
K + S + + ++ V+ +Q+ AG D L ++++L
Sbjct: 2262 LKSLHRNSKIGDTCNELNVKWSQL----AGACDDQSRALEEARDLLRFKQL---VENVLT 2314
Query: 5107 WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTD 5286
WI +KEV+ + + G+D EH +ML ER R + + + N + L+ G T
Sbjct: 2315 WINEKEVLVSTADMGRDMEHCRMLLERLDG-TRSDSTVDEQTLDEINRLGEKLVKQGRTS 2373
Query: 5287 APTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DD 5463
+ + LNE W LL + L A+ +H F D D RI EK AM DD
Sbjct: 2374 RDQVQKEQQRLNEKWRLLLGQLSHYRTELVAAMEVHTFNRDVEDTDERIHEKIAAMKSDD 2433
Query: 5464 LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVK 5643
G+D +SV L RK +D++AI +++ ++DA ++ + K + S + ++ +
Sbjct: 2434 FGKDFASVELLVRKQSALERDMSAIHQKLISHDKDAQKILEKRPPLKESILDSLK-KLEE 2492
Query: 5644 AWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMN 5823
+W+ L + R +L + L+K+++ V+ W ++V+ +M S + PKD SG L+
Sbjct: 2493 SWKKLSEAAELRNDKLNRSFKLYKYLDDVKKTEQWANQVRNKMTSHQTPKDSSGARKLLE 2552
Query: 5824 NHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWE 6003
H KAEID R + G+ L + +E+++ ++ ++ + WE
Sbjct: 2553 QHHERKAEIDGRADELRQLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKG 2612
Query: 6004 YLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEE 6183
LQ +LE + +A E WL +E + E G + LIK H AFE++ Q E
Sbjct: 2613 TLQKLLEWMLWCDEAVQCEQWLADKENQVSRGELGDTSDAVEMLIKGHSAFEETVRKQSE 2672
Query: 6184 RFLALEK 6204
+ L K
Sbjct: 2673 KIDVLVK 2679
Score = 252 bits (643), Expect = 1e-64
Identities = 299/1516 (19%), Positives = 611/1516 (39%), Gaps = 26/1516 (1%)
Frame = +1
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
+ ER + Y+EL LA R+R L DN +L +F+ + + E KE E L+
Sbjct: 903 VAERQHKISNDYRELRRLADVRRRLLSDNIKLLRFYRECDDFERW-KEIEVSLA------ 955
Query: 1975 DIVTVSHLLAKHKNAENNLRDLEK----YLDRLDVSGKELQDESIPGSDNIPPRLAEIRD 2142
D + H+ A + + D++ L ++ +L E S I R +I
Sbjct: 956 DEPSPEHVTAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRQIENRQHKINA 1015
Query: 2143 YINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLK 2322
L+ L R RL F T + ++ G + L +
Sbjct: 1016 MWENLERLRKQRAVRLEATERVADFDTTCESAREWML---------------GKFEQLDR 1060
Query: 2323 KHDDVHDELQNFDQHIKVLHAKAESLPQEA----REHPDIRQRLDTTLKQKAEL--ENLS 2484
+DV LQN ++ +K L K +L + A ++HP+ ++ + + L + L
Sbjct: 1061 NPNDVKS-LQNLERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIERKIAELRTLHADLLR 1119
Query: 2485 QLRKQRLIDALSLYK--LYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQ 2658
+ +++ L+ S K S + SWI++ K + V D+ E E + + L +
Sbjct: 1120 RAQEKMLLAEQSQGKEMFESALRDMMSWIEKTRKGMMEDVHPVDVAEAEELLKKHYELGE 1179
Query: 2659 DMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHR 2838
+K+++ +V +L R+LL P + + L + A LRD+ ++ L++
Sbjct: 1180 QIKDKKYEVEYCQELGRRLLE-RSPRMPKVEEQLQALVSEMAALRDLYRRRDTILKQQLD 1238
Query: 2839 LETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLH 3018
L+ F + + + LE D L + + V L +R +E L A +A+L++
Sbjct: 1239 LQLFNRESERIDAATKGHEAFLE-FDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFS 1297
Query: 3019 KEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQA 3198
+ ADD+ + + ++ I + + + + + + + + +L+ + + Q R+ D
Sbjct: 1298 RTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVMG 1357
Query: 3199 WLTATQRQVASEEEPQSLAEA-EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDP 3375
W+ + VAS ++ A L +H A EI +++ GD + +
Sbjct: 1358 WMHEKAKLVASGDDAALAPSAIPHRLLKHEAFEAEIIANESRIQQINREGDNLV-GKNHY 1416
Query: 3376 QYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKD 3555
+ + + + + W +L++ N+ L Q + + R + A L + E+ L
Sbjct: 1417 ESPNVEKVVRQVNAQWGDLKKQVYNKGQRLRQAADQKGLDRILEDAHAKLDEMESALNSK 1476
Query: 3556 DIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDE 3735
D L ++ L++H M K+ + G ++ +GHY ADKIH ++ +
Sbjct: 1477 DQGLDLRSVKDLLQKHTVLEQEMGLYGNKLADIENRGKKMAVEGHYDADKIHMTVGDLLK 1536
Query: 3736 RRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITSKFV 3912
R A + AQ L ++ Q + D D +WI E+K I + + R +
Sbjct: 1537 RYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVK 1596
Query: 3913 RHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQ 4092
+ + ++E+ + ++D++ A L I + EL + W EL + +
Sbjct: 1597 KQEQLEAEVNQHGGQIDKVLGQASKLVKRHHPASSQIKAKSGELESAWSELRRLLRSRRA 1656
Query: 4093 KLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQ 4272
+ ++Q Y+ A+++ W + N + ED D + K + +M Q
Sbjct: 1657 IVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQ 1716
Query: 4273 HIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRD 4452
++ ++ + + + + L +DRR ALE +++ R+
Sbjct: 1717 WLEKLDVKCSELVQSDRPHVDRFQKRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRE 1776
Query: 4453 VDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELID 4632
D + WI E+L A ++ E LQ + ++
Sbjct: 1777 SADLEQWIGEQLQTALCEDFAEDYEHLKELQSKFDEFKQSVKTGSERFTSCETAANTILR 1836
Query: 4633 EGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELY 4812
KK ++LRSAW L E ++ R L +E+ H+F D E E WM+++
Sbjct: 1837 RNPPFARDVVKKQEKLRSAWNLLCEYIETRTAKLAVAEELHRFHRDVDEFEQWMADKMAN 1896
Query: 4813 MMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE-KSPLTEQIQVRQ 4989
M +D G+D + ++HE L + + L +A + + EQI RQ
Sbjct: 1897 MPRD-LGRDVKHVHSLWQQHEALDKETHNAQPRLTKLVEEAERLKKAYPGGNAEQIGGRQ 1955
Query: 4990 AQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQW--IADKEVVAGSQENGQDYE 5163
+ + + L++ + + ++ DLL W + ++ + Q N D +
Sbjct: 1956 QTLVEEWEELRNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLQIN--DLQ 2013
Query: 5164 HVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLL 5343
+ LQ + + + + E +DG + ++ H I L A E L
Sbjct: 2014 QAEWLQTEHSRLSHEMDAREPEFTRLVSDG-EKMVNAQHYATEEIKNKTRLLKTALERLR 2072
Query: 5344 ELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYL 5520
R L + H F + + ++ I K + +G + V + ++ +
Sbjct: 2073 SEWTLRNGYLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQKKRLDTFE 2132
Query: 5521 KDIAAIGEQVAQIERDAAEL-RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMD 5697
K ++ + E+ A ++ A EL + + K +I +S+V + + LR +AR L D
Sbjct: 2133 KALSTLDERTATLDHTANELVKSRHMESK--NIAMWQSKVHEELKLLREDIEARHVMLKD 2190
Query: 5698 TSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELL-------MNNHQSLKAEIDA 5856
L F + V + W+DE + N + +D S + + HQ+L+AE+ A
Sbjct: 2191 AFALASFGSDVAQIEAWIDE---KTNGIRKARDQSSESISIEEKMKRLQTHQALEAEVAA 2247
Query: 5857 REENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
+ + + G+ L + + +S+I +L + +++ +D+ L+ ++ +F
Sbjct: 2248 NKTIVDQILHRGQQL--KSLHRNSKIGDTCNELNVKWSQLAGACDDQSRALEEARDLLRF 2305
Query: 6037 ARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTF 6216
+ +W+ +E + + + GR++E L+++ + + E+ + +L
Sbjct: 2306 KQLVENVLTWINEKEVLVSTADMGRDMEHCRMLLERLDGTRSDSTVDEQTLDEINRLGEK 2365
Query: 6217 ELKETQHREEETAKRR 6264
+K+ + ++ K +
Sbjct: 2366 LVKQGRTSRDQVQKEQ 2381
Score = 244 bits (622), Expect = 3e-62
Identities = 302/1489 (20%), Positives = 576/1489 (38%), Gaps = 22/1489 (1%)
Frame = +1
Query: 1864 RRLEDNKRLCQFWWDVAELEHG-IKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
+R E ++L Q + A+L +K + VL + GR V L K + ++
Sbjct: 410 QRQEKLEQLAQRFHKKAKLRDSWLKSVQVVLEEMEHGRSASQVEKTLKKQQAISTDILAR 469
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
E L EL E S+ I EI D +L L RK L +
Sbjct: 470 EDRFKMLTAMCNELCTEKYHESEKIRGMEREIIDRWTQLLALLEQRKRALMSLNDLMSLL 529
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
D D + LY + + DVGK V+ LL KHD V ++ + L A +
Sbjct: 530 RDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLLGKHDLVDAQINAHGSLLSKLSQAANNY 589
Query: 2401 PQEAREHPDIRQR-LDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKG 2577
+ E D+ QR LD Q L L + R+ L A SL++ D + +W+ EK
Sbjct: 590 IRHKEEQFDVLQRKLDEVTSQYNTLVELCRSRRLALERARSLFQFIQDHEEEMAWLAEKE 649
Query: 2578 KLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHR 2757
KL T + DI V + +E +M+ A+ + +L+ + +DI R
Sbjct: 650 KLCTTALNSGDISAVPQTTLLYKNVEMEMQTHWARSKGMIAGGERLVQ-SGQSKEDIQRR 708
Query: 2758 QNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLS 2937
++N W +LR VD N L A + + D E +WI +K +++ SD L D
Sbjct: 709 LTQMNQGWERLRVAVDALGNWLSEARHAQQYFQDVNEAESWIREKMPLVK-SDDLGRDEG 767
Query: 2938 GVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNK 3117
L +R + +E ++ A + + L E + Q A + V +
Sbjct: 768 AAESLLQRHARLEEEIRAYKNDITRL-------EEMQSQLANSAFHTATTSQSVQETEEV 820
Query: 3118 KVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIRE 3297
V + E G+ R ++ E +L E A R+
Sbjct: 821 TVPQIEMAYKYEGNGMR-------------------VAKGEVLALLEKSTPEWWRALKRD 861
Query: 3298 EIDGYAEDYKKMRAMGDRVTQDQT-----------DPQYMFLRQRLAGLQEGWEELQRMW 3444
+GY G+ VT QT + + + +R + + EL+R+
Sbjct: 862 GTEGYVPANYCKVVPGESVTVTQTTQKTTTTVEGNETKSSVVAERQHKISNDYRELRRLA 921
Query: 3445 DNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTM 3624
D R+ LLS + L F R+ E + E LA + P+ + + + + + T
Sbjct: 922 DVRRRLLSDNIKLLRFYRECDDFE-RWKEIEVSLADEPSPEHVTAFRRKFDKLEADMKTN 980
Query: 3625 DANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQ 3804
+++ + + L +GH + +I + I+ ++ +L+ +
Sbjct: 981 GGT--QLKHINDIANDLISEGHGQSRQIENRQHKINAMWENLERLRKQRAVRLEATERVA 1038
Query: 3805 QFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAI 3984
F + C+ REW+ K + D D K++ Q + +L ++++ L+ A
Sbjct: 1039 DFDTTCESAREWMLGKFEQL-DRNPNDVKSL-------QNLERDLKPLEDKIAALEKLAA 1090
Query: 3985 NLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ 4164
+ D PE I+ +I EL T +L + +EK + ++++ ++ DM W +
Sbjct: 1091 AVKKDHPEEAAAIERKIAELRTLHADLLRRAQEKMLLAEQSQGKEMFESALRDMMSWIEK 1150
Query: 4165 LENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIK 4344
M + P D+ ++K + + ++ K ++ P
Sbjct: 1151 TRKGMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLLERSP------- 1203
Query: 4345 AHRLAVQEQLQRL---QAPLDD---RRKALERKKAAFQ-FGRDVDDEKLWISERLVLAKA 4503
V+EQLQ L A L D RR + +++ Q F R+ + +
Sbjct: 1204 -RMPKVEEQLQALVSEMAALRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEF 1262
Query: 4504 QNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELR 4683
NLG+S+ L K + L ++D E + ++I HA+ E++ +++
Sbjct: 1263 DNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVL 1322
Query: 4684 SAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQ-ELYMMQDERGKDEFSTKNQ 4860
+ + ++ A RK L S + + + E WM E+ +L D+ + ++
Sbjct: 1323 ARREAVRRAAAQRKKQLEASLEYQEMRREADEVMGWMHEKAKLVASGDDAALAPSAIPHR 1382
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXX 5040
+ KHE +++I I+ + + V + + ++ Q+ + L+
Sbjct: 1383 LLKHEAFEAEIIANESRIQQINREGDNLVGKNHYESPNVEKVVRQVNAQWGDLKKQVYNK 1442
Query: 5041 XXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENI 5220
L R ++D + + E S++ G D V+ L ++ ++
Sbjct: 1443 GQRLRQAADQKGLDRILEDAHAKLDEMESALNSKDQGLDLRSVKDLLQKHTVLEQEMGLY 1502
Query: 5221 GSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKF 5400
G++ N G + GH DA I + L + + + R L+ SRL H+
Sbjct: 1503 GNKLADIENRGKKMAV-EGHYDADKIHMTVGDLLKRYAAMKGPAQRRKGDLDESRLWHQL 1561
Query: 5401 YHDCRDCLSRIMEKTH-AMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAE 5577
D L I EK A D GR + + +K + ++ G Q+ ++ A++
Sbjct: 1562 VFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLGQASK 1621
Query: 5578 LRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDE 5757
L + + I ++ E+ AW LR L +R + + +++ ++ WM+E
Sbjct: 1622 LVKRHHPASS-QIKAKSGELESAWSELRRLLRSRRAIVDWGVKEQQYLFDAAEVESWMNE 1680
Query: 5758 VKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIE 5937
+ + S++ D L+ H++L ++ + +L+ +
Sbjct: 1681 KRNALASEDYGNDEDAARKLLAKHRALCEDMTTYRQWLEKLDVKCSELVQSDRPHVDRFQ 1740
Query: 5938 KKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNL 6117
K+ +L E + + EDR L+ + +Y++ R++A E W+ Q + +++ +
Sbjct: 1741 KRQDELVHEFDSLSKLAEDRRNALEDAVCLYEYMRESADLEQWIGEQLQTALCEDFAEDY 1800
Query: 6118 EETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRR 6264
E +L K + F++S ERF + E L+ + K++
Sbjct: 1801 EHLKELQSKFDEFKQSVKTGSERFTSCETAANTILRRNPPFARDVVKKQ 1849
Score = 117 bits (294), Expect = 3e-24
Identities = 147/804 (18%), Positives = 317/804 (39%), Gaps = 17/804 (2%)
Frame = +1
Query: 844 ELMENDKMINRYETLSSDLLEWINAKIQLLNERHF--ENNLEGVQRQLTEFND--YRTQE 1011
+++E+ K + + +L+ WI AK+QL + F NL ++ F+ ++
Sbjct: 2718 DMLEDSKRYHEFIRHCGELIIWITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELVENEK 2777
Query: 1012 KPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKL-IADINRAWQSLEKAEHERELVL 1188
+ + +GE + A+N F+ + K + ++ W L + L
Sbjct: 2778 RLSNVERQGE----------ELVADNH--FMSEQVKAQLVELRSGWDEL-----RTKSAL 2820
Query: 1189 KEELIRQE-KLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIET 1365
K + +R+ +L L RK E E WL + + ++ ++ G D+ S E KK + ++T
Sbjct: 2821 KTQRLREAFELHSL----QRKVEDLEKWLDKVEGELASEDHGRDMLSTELLIKKLDTLQT 2876
Query: 1366 DIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMA 1545
+I R A ++ + ++R E +
Sbjct: 2877 EIAG---RSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVD 2933
Query: 1546 IQKIFHXXXXXXXXXXXIKSRL---LSEDLGAHLMDVEDLLQKHALLESDINIIGERVNN 1716
Q F + ++ S + G L L +KHA LE ++ +++
Sbjct: 2934 AQAFFEWVKAAEEDLEWLSDKMPLASSGESGDSLQSALSLQKKHAALEKELETRQSAMDD 2993
Query: 1717 SIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQ 1896
+ G D + G I + D L L + R+ L++ +
Sbjct: 2994 T--------EKRGKDMIRQRHFASGHIQKILDRLSTAMLTLKESCGLRRDLLQEAIDAHE 3045
Query: 1897 FWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGK 2076
++ + E E ++EQ + S + GRD L + + + + +DRL
Sbjct: 3046 YYTEETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRAD 3105
Query: 2077 ELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYD 2256
L + +I + ++ L A R+ ++ +Y++F ADD+ +L +
Sbjct: 3106 GLLAREHHDAMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLRE 3165
Query: 2257 TLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREH-PDIR 2433
R S+ED G+D Q ++++ + EL + + ++ E L + + I
Sbjct: 3166 KERTASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVALVQRSQEDLLRSGHPYGASIT 3225
Query: 2434 QRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATL----VP 2601
+ + + ++ RKQ L A +++ +AD +W+ +K + +
Sbjct: 3226 AKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQTLNWLQDKEATGVAMEQEDLS 3285
Query: 2602 GRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARW 2781
D+ V+ R D MK E +V + A +L N D H + +
Sbjct: 3286 RADLASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWN---SFPDTRHHLEVRRLDME 3342
Query: 2782 AQLRDMVDQKRNELERAHR---LETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL 2952
QL+D+++ + LER L+++ + +E + W+++ + S+ L D++ L
Sbjct: 3343 EQLKDILEAAKKHLERLRHMQSLQSYFQEYREMMQWMKNMQTTM-TSEQLPRDVASCESL 3401
Query: 2953 QRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREH 3132
RR ++ + +D ++ + + +Q I+E ++ + + W++L + ++
Sbjct: 3402 VRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVEVLEKSWEMLCEIWKDR 3461
Query: 3133 EAKLDEAGDLQRFLRDLDHFQAWL 3204
+E D+Q++ ++ + +WL
Sbjct: 3462 AELYEENMDVQKWKQNAEQLDSWL 3485
>gi|7706190|ref|NP_057726.1| spectrin, beta, non-erythrocytic 5; beta
V spectrin [Homo sapiens]
gi|17369320|sp|Q9NRC6|SPCR_HUMAN Spectrin beta chain, brain 4
(Spectrin, non-erythroid beta chain 4) (Beta-V spectrin)
(BSPECV)
gi|7638038|gb|AAF65317.1| beta V spectrin [Homo sapiens]
Length = 3674
Score = 844 bits (2181), Expect = 0.0
Identities = 589/2131 (27%), Positives = 1017/2131 (47%), Gaps = 65/2131 (3%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNS--HLVRVSCKVQDLYMDMRDGKMLLRLLAVLSG 249
+E I+ L +Q+KTFTKW+N+ + K+++LY ++ DG LLRLL ++SG
Sbjct: 40 YETGHIRKLQARHMQMQEKTFTKWINNVFQCGQAGIKIRNLYTELADGIHLLRLLELISG 99
Query: 250 ERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRF 429
E LP P+ G++R+H LEN + L FLR + V + +G +IVDG+ L LGLIW IILRF
Sbjct: 100 EALPPPSRGRLRVHFLENSSRALAFLRAK-VPVPLIGPENIVDGDQTLILGLIWVIILRF 158
Query: 430 QIQDITFEDAD---NHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHK 600
QI I+ + + + S KEALL+WCQ KTA Y NVN+ +FS SW DGL FNALIH
Sbjct: 159 QISHISLDKEEFGASAALLSTKEALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHA 218
Query: 601 HRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
HRPDL+DY +L+ L+NL AF AE +LG+A+ LD EDV QPDE+SI+TYV YY
Sbjct: 219 HRPDLLDYGSLRPDRPLHNLAFAFLVAEQELGIAQLLDPEDVAAAQPDERSIMTYVSLYY 278
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
HY ++L Q +R+ K++ +L E + + +YE L +DLL WI K L R F ++L
Sbjct: 279 HYCSRLHQGQTVQRRLTKILLQLQETELLQTQYEQLVADLLRWIAEKQMQLEARDFPDSL 338
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
+++ L F +RTQEKPP+ ++G E LLF LQ+A++A N+RPF+P EG +A++++
Sbjct: 339 PAMRQLLAAFTIFRTQEKPPRLQQRGAAEALLFRLQTALQAQNRRPFLPHEGLGLAELSQ 398
Query: 1141 AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNF-GND 1317
W LE AE R L++ L++ ++LE LA RF RKA +RE++L + ++++ Q
Sbjct: 399 CWAGLEWAEAARSQALQQRLLQLQRLETLARRFQRKAALRESFLKDAEQVLDQARAPPAS 458
Query: 1318 LSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXX 1497
L++VEAA ++ +E I E R YH A + R+E V
Sbjct: 459 LATVEAAVQRLGMLEAGILPQEGRFQALAEIADILRQEQYHSWADVARRQEEVTVRWQRL 518
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
+R ++ A+ + ++ S G L +V +LLQ+H LL
Sbjct: 519 LQHLQGQRKQVADMQAVLSLLQEVEAASHQLEELQEPARSTACGQQLAEVVELLQRHDLL 578
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E+ ++ G V++ AQ+ D G+ + + ++ L + + L+ L
Sbjct: 579 EAQVSAHGAHVSH---LAQQTAELDSSLGTSVE-----VLQAKARTLAQLQQSLVALVRA 630
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
R+ LE + +F + E E +KE Q + + GRD+ ++ L KHK E +
Sbjct: 631 RRALLEQTLQRAEFLRNCEEEEAWLKECGQRVGNAALGRDLSQIAGALQKHKALEAEVHR 690
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
+ L G++L P + R ++ L+ R RL + Q+
Sbjct: 691 HQAVCVDLVRRGRDLSARRPPTQPDPGERAEAVQGGWQLLQTRVVGRGARLQTALLVLQY 750
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAK--- 2388
F DA + +L + + G+D+ + LL++H + L+ F ++ L +
Sbjct: 751 FADAAEAASWLRERRSSLERASCGQDQAAAETLLRRHVRLERVLRAFAAELRRLEEQGRA 810
Query: 2389 ------------AESLPQEAREHP-------------------------------DIRQR 2439
A S P E+ +P I Q
Sbjct: 811 ASARASLFTVNSALSPPGESLRNPGPWSEASCHPGPGDAWKMALPAEPDPDFDPNTILQT 870
Query: 2440 LDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEE 2619
D + L L+QLR+ RL +A++L+ S ++ W++++ LL + P D
Sbjct: 871 QDHLSQDYESLRALAQLRRARLEEAMALFGFCSSCGELQLWLEKQTVLLQRVQPQAD--T 928
Query: 2620 VEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDM 2799
+E+M+ +++ + + V+ A QL NS I +Q +L+ RW QL +
Sbjct: 929 LEVMQLKYENFLTALAVGKGLWAEVSSSAEQLRQRYPGNSTQIQRQQEELSQRWGQLEAL 988
Query: 2800 VDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMER 2979
+K +L + + +F +C T + D VL +AL S + L + ++
Sbjct: 989 KREKAVQLAHSVEVCSFLQECGPTQVQLRD---VLLQLEALQPGSS--EDTRHALQLAQK 1043
Query: 2980 DLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGD 3159
++ ++ L +E E+Q ++ ++ + + + ++V + + E
Sbjct: 1044 KTLVLERRVYFLQSVVVKVEEPGYAESQPLQGQVETLQGLLKQVQEQVAQRARRQAETQA 1103
Query: 3160 LQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRA 3339
Q FL++ W + Q Q+ S+E +A A++LL +H + EEI + E +++ A
Sbjct: 1104 RQSFLQESQQLLLWAESVQAQLRSKEVSVDVASAQRLLREHQDLLEEIHLWQERLQQLDA 1163
Query: 3340 MGDRVTQ-DQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAE 3516
+ D D Q + R+ G Q+G +EL+ +W+ RQ L +GL LQ F R+
Sbjct: 1164 QSQPMAALDCPDSQEVPNTLRVLG-QQG-QELKVLWEQRQQWLQEGLELQKFGREVDGFT 1221
Query: 3517 VMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYA 3696
+ + +L D++ + + +A + L++H++F + + A+ G++L Q H A
Sbjct: 1222 ATCANHQAWLHLDNLGEDVREALSLLQQHREFGRLLSTLGPRAEALRAHGEKLVQSQHPA 1281
Query: 3697 ADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDET 3876
A + ++ ++I + + ++++ ++L +L LQ++ D EL +W+EEK + A E
Sbjct: 1282 AHTVREQLQSIQAQWTRLQGRSEQRRRQLLASLQLQEWKQDVAELMQWMEEKGLMAAHEP 1341
Query: 3877 YRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQW 4056
+ I RH+A +SEL A + ++ L+ L +P I +++ L ++W
Sbjct: 1342 SGARRNILQTLKRHEAAESELLATRRHVEALQQVGRELLSRRPCGQEDIQTRLQGLRSKW 1401
Query: 4057 DELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQ 4236
+ L + E+G +L A +Q+ ++ + D KE QLE + + DL + ++
Sbjct: 1402 EALNRKMTERGDELQQAGQQEQLLRQLQDAKEQLEQLEGALQSSETGQDLRSSQRLQKRH 1461
Query: 4237 HLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKAL 4416
+E+E A + P LE + H +L+ LQ L R L
Sbjct: 1462 QQLESESRTLAAKM-AALASMAHGMAASPAILEETQKH----LRRLELLQGHLAIRGLQL 1516
Query: 4417 ERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWI 4596
+ QF + E W++E + + E L L + + L E+ H+ +
Sbjct: 1517 QASVELHQFCHLSNMELSWVAEHMPHGSPTSYTECLNGAQSLHRKHKELQVEVKAHQGQV 1576
Query: 4597 NQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCG 4776
++ ++G+ L GH ++ QEL W EL+ A + R L ++ Q+ D
Sbjct: 1577 QRVLSSGRSLAASGHPQAQHIVEQCQELEGHWAELERACEARAQCLQQAVTFQQYFLDVS 1636
Query: 4777 EAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEK 4956
E E W+ E+ + + G+DE +T I KH+ LQ ++ + ++ L A +
Sbjct: 1637 ELEGWVEEKRPLVSSRDYGRDEAATLRLINKHQALQEELAIYWSSMEELDQTAQTLTGPE 1696
Query: 4957 SPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIA-DKEVVA 5133
P EQ +V Q ++ + LQ+ + RE +DL W+A K+
Sbjct: 1697 VP--EQQRVVQERLREQLRALQELAATRDRELEGTLRLHEFLREAEDLQGWLASQKQAAK 1754
Query: 5134 GSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKD 5313
G + G+D EH L +F +F E +GS+RVA ++L+ GH+ P + +
Sbjct: 1755 GGESLGEDPEHALHLCTKFAKFQHQVE-MGSQRVAACRLLAESLLERGHSAGPMVRQRQQ 1813
Query: 5314 SLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGA 5493
L AW L EL R L + + + D + L+++ EK ++P+++ RD + A
Sbjct: 1814 DLQTAWSELWELTQARGHALRDTETTLRVHRDLLEVLTQVQEKATSLPNNVARDLCGLEA 1873
Query: 5494 LSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCD 5673
R HQ +++ Q+ ++ A ++ G +A + R+ V +AW L+ +
Sbjct: 1874 QLRSHQGLERELVGTERQLQELLETAGRVQKLCPGPQAHAVQQRQQAVTQAWAVLQRRME 1933
Query: 5674 ARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEID 5853
R ++L L +F VRD W V++++ +E ++ S L ++ HQ L+AE++
Sbjct: 1934 QRRAQLERARLLARFRTAVRDYASWAARVRQDLQVEESSQEPSSGPLKLSAHQWLRAELE 1993
Query: 5854 AREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQ 6033
ARE+ + LG+ L + E++++L L +R ++ + W + E LQ +
Sbjct: 1994 AREKLWQQATQLGQQALLAAGTPTKEVQEELRALQDQRDQVYQTWARKQERLQAEQQEQL 2053
Query: 6034 FARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL-EKLT 6210
F R+ E L AQE L + G ++EE +LI+KHE F K AQ+++ AL E+L
Sbjct: 2054 FLRECGRLEEILAAQEVSLKTSALGSSVEEVEQLIRKHEVFLKVLTAQDKKEAALRERLK 2113
Query: 6211 TFE----------LKETQHREEETAKRRGPA 6273
T L + + R +E A+ RG A
Sbjct: 2114 TLRRPRVRDRLPILLQRRMRVKELAESRGHA 2144
Score = 506 bits (1302), Expect = e-141
Identities = 441/1875 (23%), Positives = 790/1875 (41%), Gaps = 24/1875 (1%)
Frame = +1
Query: 1129 DINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVS-QDN 1305
D+ AW L + R L++ + R +R ++ E ++ S +N
Sbjct: 1814 DLQTAWSELWELTQARGHALRDT--------ETTLRVHR--DLLEVLTQVQEKATSLPNN 1863
Query: 1306 FGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAK-INERKENVXX 1482
DL +EA + H+ +E ++ E + QA + +R++ V
Sbjct: 1864 VARDLCGLEAQLRSHQGLERELVGTERQLQELLETAGRVQKLCPGPQAHAVQQRQQAVTQ 1923
Query: 1483 XXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQ 1662
RR +LE + + + ++ L E+ L
Sbjct: 1924 AWAVLQRRMEQRRAQLERARLLARFRTAVRDYASWAARVRQDLQVEESSQEPSSGPLKLS 1983
Query: 1663 KHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELL 1842
H L +++ + + Q+ G + E LQ + ++
Sbjct: 1984 AHQWLRAELEAREKLWQQATQLGQQALLAAGTPTK--------EVQEELRALQDQRDQVY 2035
Query: 1843 DLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAE 2022
A ++ RL+ ++ F + LE + QE L ++ G + V L+ KH+
Sbjct: 2036 QTWARKQERLQAEQQEQLFLRECGRLEEILAAQEVSLKTSALGSSVEEVEQLIRKHEVFL 2095
Query: 2023 NNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGV 2202
L +K L K L+ + D +P L ++KEL+ SR L +
Sbjct: 2096 KVLTAQDKKEAALRERLKTLRRPRV--RDRLPILLQRRM----RVKELAESRGHALHASL 2149
Query: 2203 EYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLH 2382
F A + ++ + + D L KH E+Q ++ + +
Sbjct: 2150 LMASFTQAATQAEDWIQAWAQQLKEPVPPGDLRDKLKPLLKHQAFEAEVQAHEEVMTSVA 2209
Query: 2383 AKAESLPQEAREHP---DIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSV 2553
K E+L A+ HP ++ QRL K +L LR Q L D + + D
Sbjct: 2210 KKGEALL--AQSHPRAGEVSQRLQGLRKHWEDLRQAMALRGQELEDRRNFLEFLQRVDLA 2267
Query: 2554 ESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQ---EAKVTNVNDLARQLLNV 2724
E+WI EK + G+D+E ++ R + +A + +++DL+ QL N
Sbjct: 2268 EAWIQEKEVKMNVGDLGQDLEHCLQLRRRLREFRGNSAGDTVGDACIRSISDLSLQLKNR 2327
Query: 2725 EHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVL 2904
+ I R+++LN RWA + + + +LE A + + I++K ++
Sbjct: 2328 DPEEVKIICQRRSQLNNRWASFHGNLLRYQQQLEGALEIHVLSRELDNVTKRIQEKEALI 2387
Query: 2905 EDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIK 3084
+ D DL V +L R+ +ER++ IQA+++SL +E + + P+ A +R +
Sbjct: 2388 QALDC-GKDLESVQRLLRKHEELEREVHPIQAQVESLEREVGRLCQRSPEAAHGLRHRQQ 2446
Query: 3085 RIHQVWDILNKKVREHEAKLD---EAGDLQRFLRDLDHFQAWLTATQR---QVASEEEPQ 3246
+ + W L + ++ LD +A LQ L++L L + QR Q+ + P+
Sbjct: 2447 EVAESWWQLRSRAQKRREALDALHQAQKLQAMLQEL------LVSAQRLRAQMDTSPAPR 2500
Query: 3247 SLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWE 3426
S EA ++L +H + E+D + + R+ G ++ P +RQ LAGL++
Sbjct: 2501 SPVEARRMLEEHQECKAELDSWTDSISLARSTGQQLLT-AGHPFSSDIRQVLAGLEQELS 2559
Query: 3427 ELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQ 3606
L+ W Q L Q L LQ+FL ++ E L +E+ LA + + L E L +H+
Sbjct: 2560 SLEGAWQEHQLQLQQALELQLFLSSVEKMERWLCSKEDSLASEGLWDPLAPMEPLLWKHK 2619
Query: 3607 DFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLK 3786
++ KI A+ L Q GH A + + + R+ A +A +L+
Sbjct: 2620 MLEWDLEVQAGKISALEATARGLHQGGHPEAQSALGRCQAMLLRKEALFRQAGTRRHRLE 2679
Query: 3787 DALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQ 3966
+ LQ FL D E+ W+ EK + A +E D + ++ + Q FQ+EL A+ + +
Sbjct: 2680 ELRQLQAFLQDSQEVAAWLREKNLVALEEGLLDTAMLPAQLQKQQNFQAELDASMHQQQE 2739
Query: 3967 LKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADM 4146
L+ L I ++EEL W EL+ +++K KL A +S+ ++
Sbjct: 2740 LQREGQRLLQGGHPASEAIQERLEELGALWGELQDNSQKKVAKLQKACEALRLRRSMEEL 2799
Query: 4147 KEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPD 4326
+ W +E E+ L V + Q +E + KKA+ +
Sbjct: 2800 ENWLEPIEVELRAPTVGQALPGVGELLGTQRELEAAVDKKARQAEALLGQAQAFVREGHC 2859
Query: 4327 ELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQ 4506
++++ + ++ + L+ PL +RR ALE + +F RD D+E W+ E+L LA AQ
Sbjct: 2860 LAQDVEEQARRLLQRFKSLREPLQERRTALEARSLLLKFFRDADEEMAWVQEKLPLAAAQ 2919
Query: 4507 NLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRS 4686
+ G+SL LQ+ Q L +E+ +HE + G +L+ GH ++Q+L
Sbjct: 2920 DYGQSLSAVRHLQEQHQNLESEMSSHEALTRVVLGTGYKLVQAGHFAAHEVAARVQQLEK 2979
Query: 4687 AWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIK 4866
A L+ R+ L ++++A QFL + EA +W++E+ + ++ G +T+ ++
Sbjct: 2980 AMAHLRAEAARRRLLLQQAQEAQQFLTELLEAGSWLAERGHVLDSEDMGHSAEATQALLR 3039
Query: 4867 KHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXX 5046
+ E + D++ F+ I L A K+P + ++ + + + +A L
Sbjct: 3040 RLEATKRDLEAFSPRIERLQQTAALLESRKNPESPKVLAQLQAVREAHAELLRRAEARGH 3099
Query: 5047 XXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGS 5226
+ L RE L W+ K A SQ+ GQD E V++L+E+F F ++ +++G
Sbjct: 3100 GLQEQLQLHQLERETLLLDAWLTTKAATAESQDYGQDLEGVKVLEEKFDAFRKEVQSLGQ 3159
Query: 5227 ERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYH 5406
+V TL P I + + AWE L + + R + L A+ +H F
Sbjct: 3160 AKVYALRKLAGTLERGAPRRYPHIQAQRSRIEAAWERLDQAIKARTENLAAAHEVHSFQQ 3219
Query: 5407 DCRDCLSRIMEKTHAMP-DDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELR 5583
+ R+ EKT M +D G SSV L ++H+ +++ A+ ++VA+++ +A L
Sbjct: 3220 AAAELQGRMQEKTALMKGEDGGHSLSSVRTLQQQHRRLERELEAMEKEVARLQTEACRL- 3278
Query: 5584 DGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVK 5763
G ++V +AW L+ R L + F+ ++LL W E +
Sbjct: 3279 ----GQLHPAAPGGLAKVQEAWATLQAKAQERGQWLAQAAQGHAFLGRCQELLAWAQERQ 3334
Query: 5764 REMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKK 5943
+S+E +DV+G E L+ H+ L EI G+ L++ H+ S+E+ +
Sbjct: 3335 ELASSEELAEDVAGAEQLLGQHEELGQEIRECRLQAQDLRQEGQQLVDNSHFMSAEVTEC 3394
Query: 5944 LIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEE 6123
L +L E+ W RW+ + + + AE+WL E L+ +YG ++ +
Sbjct: 3395 LQELEGRLQELEEAWALRWQRCAESWGLQKLRQRLEQAEAWLACWEGLLLKPDYGHSVSD 3454
Query: 6124 TIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRS-- 6297
L+ +H+ EK AQEE+F ++K E+++ + + K P GS S
Sbjct: 3455 VELLLHRHQDLEKLLAAQEEKFAQMQKT---EMEQELLLQPQELK---PGRAGSSLTSFQ 3508
Query: 6298 -TPAAETSFGAQ------DDGAKQGEAFEGTLIRKHTYESLDRKAANRSWEKLYAVLRQN 6456
P+ GAQ AK EG+L K R+ ++ SW+ L+ +
Sbjct: 3509 WRPSGHQGLGAQLAETRDPQDAKGTPTMEGSLEFKQHLLPGGRQPSSSSWDSCRGTLQGS 3568
Query: 6457 ELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEED 6636
LS + D + E V + L G +K+ SLRL GAE LF SEE
Sbjct: 3569 SLSLFLDERMAAEKVASIALLDLTGARCERLRGRHGRKHTFSLRLTSGAEILFAAPSEEQ 3628
Query: 6637 MQRWLTELQVATGQA 6681
+ W L Q+
Sbjct: 3629 AESWWRALGSTAAQS 3643
Score = 306 bits (785), Expect = 3e-81
Identities = 335/1792 (18%), Positives = 709/1792 (38%), Gaps = 27/1792 (1%)
Frame = +1
Query: 943 HFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRAN------NQRPFV 1104
H +N E V+ L+ +R E G L L A+RA+ +Q P
Sbjct: 1232 HLDNLGEDVREALSLLQQHR---------EFGRLLSTLGPRAEALRAHGEKLVQSQHPAA 1282
Query: 1105 PREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQ 1284
+ + I W L+ +R L L QE + +A W+ E
Sbjct: 1283 HTVREQLQSIQAQWTRLQGRSEQRRRQLLASLQLQEWKQDVAELMQ--------WMEEKG 1334
Query: 1285 RLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINER 1464
+ + + G + ++ K+HEA E+++ A Q I R
Sbjct: 1335 LMAAHEPSGARRNILQTL-KRHEAAESELLATRRHVEALQQVGRELLSRRPCGQEDIQTR 1393
Query: 1465 KENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMD 1644
+ + R L+ + +++ ++ L S + G L
Sbjct: 1394 LQGLRSKWEALNRKMTERGDELQQAGQQEQLLRQLQDAKEQLEQLEGALQSSETGQDLRS 1453
Query: 1645 VEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQK 1824
+ L ++H LES+ + ++ + A P ++E L +
Sbjct: 1454 SQRLQKRHQQLESESRTLAAKMAALASMAHGMA------------ASPAILEETQKHL-R 1500
Query: 1825 RYKELLDLAAERKRRLEDNKRLCQFW--------WDVAELEHGIKEQEQVLSSTDTGRDI 1980
R + L A R +L+ + L QF W + HG S T +
Sbjct: 1501 RLELLQGHLAIRGLQLQASVELHQFCHLSNMELSWVAEHMPHG--------SPTSYTECL 1552
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
L KHK + ++ + + R+ SG+ L P + +I + E+ + +L+
Sbjct: 1553 NGAQSLHRKHKELQVEVKAHQGQVQRVLSSGRSLAASGHPQAQHIVEQCQELEGHWAELE 1612
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
+R + L V + Q+F D +++ ++ + ++SS D G+DE L+ KH +
Sbjct: 1613 RACEARAQCLQQAVTFQQYFLDVSELEGWVEEKRPLVSSRDYGRDEAATLRLINKHQALQ 1672
Query: 2341 DELQNFDQHIKVLHAKAESL--PQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDA 2514
+EL + ++ L A++L P+ + +++RL L+ L+ L+ R + L
Sbjct: 1673 EELAIYWSSMEELDQTAQTLTGPEVPEQQRVVQERLREQLR---ALQELAATRDRELEGT 1729
Query: 2515 LSLYKLYSDADSVESWI-DEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTN 2691
L L++ +A+ ++ W+ +K G D E + +F + ++ +V
Sbjct: 1730 LRLHEFLREAEDLQGWLASQKQAAKGGESLGEDPEHALHLCTKFAKFQHQVEMGSQRVAA 1789
Query: 2692 VNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQET 2871
LA LL H + RQ L W++L ++ + + L D E
Sbjct: 1790 CRLLAESLLERGHSAGPMVRQRQQDLQTAWSELWELTQARGHALRDTETTLRVHRDLLEV 1849
Query: 2872 VTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERP 3051
+T +++K L ++ + DL G+ R +ER+L + +L L + A +++ P
Sbjct: 1850 LTQVQEKATSLPNN--VARDLCGLEAQLRSHQGLERELVGTERQLQELLETAGRVQKLCP 1907
Query: 3052 -QEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA 3228
+A A+++ + + Q W +L +++ + A+L+ A L RF + + +W ++ +
Sbjct: 1908 GPQAHAVQQRQQAVTQAWAVLQRRMEQRRAQLERARLLARFRTAVRDYASWAARVRQDLQ 1967
Query: 3229 SEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAG 3408
EE Q + L+ H +R E++ + +++ +G + P +++ L
Sbjct: 1968 VEESSQEPSSGPLKLSAHQWLRAELEAREKLWQQATQLGQQALLAAGTPT-KEVQEELRA 2026
Query: 3409 LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN 3588
LQ+ +++ + W +Q L Q+FLR+ + E +L+ QE L + S+E+ E
Sbjct: 2027 LQDQRDQVYQTWARKQERLQAEQQEQLFLRECGRLEEILAAQEVSLKTSALGSSVEEVEQ 2086
Query: 3589 QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
+++H+ F+ + A D+K A+ L ++ + + +RR +E A+
Sbjct: 2087 LIRKHEVFLKVLTAQDKKEAALRERLKTL------RRPRVRDRLPILLQRRMRVKELAES 2140
Query: 3769 VLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDET-YRDAKTITSKFVRHQAFQSELAA 3945
L +L + F + +WI+ + ++ D + ++HQAF++E+ A
Sbjct: 2141 RGHALHASLLMASFTQAATQAEDWIQAWAQQLKEPVPPGDLRDKLKPLLKHQAFEAEVQA 2200
Query: 3946 NKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLY 4125
++E + + L G + +++ L W++L + +GQ+L D +
Sbjct: 2201 HEEVMTSVAKKGEALLAQSHPRAGEVSQRLQGLRKHWEDLRQAMALRGQELEDRRNFLEF 2260
Query: 4126 VQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXX 4305
+Q + + W + E +M D DL + ++ L E +
Sbjct: 2261 LQRVDLAEAWIQEKEVKMNVGDLGQDLE--HCLQLRRRLREFRGNSAGDTVGDACIRSIS 2318
Query: 4306 XXXXH-----PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKL 4470
P+E++ I R + + L ++ LE R++D+
Sbjct: 2319 DLSLQLKNRDPEEVKIICQRRSQLNNRWASFHGNLLRYQQQLEGALEIHVLSRELDNVTK 2378
Query: 4471 WISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANG 4650
I E+ L +A + G+ L RL + + L E+ + + + L
Sbjct: 2379 RIQEKEALIQALDCGKDLESVQRLLRKHEELEREVHPIQAQVESLEREVGRLCQRSPEAA 2438
Query: 4651 PAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQD-- 4824
+ QE+ +W +L+ + R+ L +A + E +S Q L D
Sbjct: 2439 HGLRHRQQEVAESWWQLRSRAQKRREALDALHQAQKL--QAMLQELLVSAQRLRAQMDTS 2496
Query: 4825 ERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEK 5004
+ + +++H+ ++++D + D+I + + + P + I+ A +E+
Sbjct: 2497 PAPRSPVEARRMLEEHQECKAELDSWTDSISLARSTGQQLLTAGHPFSSDIRQVLAGLEQ 2556
Query: 5005 LYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQE 5184
+ L+ ++ + +W+ KE S+ ++ L
Sbjct: 2557 ELSSLEGAWQEHQLQLQQALELQLFLSSVEKMERWLCSKEDSLASEGLWDPLAPMEPLLW 2616
Query: 5185 RFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRA 5364
+ + D E + + +++ L GH +A + ++ E L TR
Sbjct: 2617 KHKMLEWDLE-VQAGKISALEATARGLHQGGHPEAQSALGRCQAMLLRKEALFRQAGTRR 2675
Query: 5365 QILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGE 5544
LE R L F D ++ + + EK ++ D++ + A +K QN+ ++ A
Sbjct: 2676 HRLEELRQLQAFLQDSQEVAAWLREKNLVALEEGLLDTAMLPAQLQKQQNFQAELDASMH 2735
Query: 5545 QVAQIERDAAE-LRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFM 5721
Q +++R+ L+ G+ +A I R E+ W L+ + ++L + +
Sbjct: 2736 QQQELQREGQRLLQGGHPASEA--IQERLEELGALWGELQDNSQKKVAKLQKACEALRLR 2793
Query: 5722 NMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDL 5901
+ +L W++ ++ E+ + + + GV L+ + L+A +D + A + +
Sbjct: 2794 RSMEELENWLEPIEVELRAPTVGQALPGVGELLGTQRELEAAVDKKARQAEALLGQAQAF 2853
Query: 5902 LNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQE 6081
+ H + ++E++ +L + ++R L+ + +F RDA +W+ +
Sbjct: 2854 VREGHCLAQDVEEQARRLLQRFKSLREPLQERRTALEARSLLLKFFRDADEEMAWVQEKL 2913
Query: 6082 PYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQH 6237
P +++YG++L L ++H+ E S + E + T ++L + H
Sbjct: 2914 PLAAAQDYGQSLSAVRHLQEQHQNLE-SEMSSHEALTRVVLGTGYKLVQAGH 2964
Score = 253 bits (647), Expect = 3e-65
Identities = 347/1766 (19%), Positives = 664/1766 (36%), Gaps = 62/1766 (3%)
Frame = +1
Query: 1147 QSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSS 1326
QSL R +L++ L R E F R E E WL E + V G DLS
Sbjct: 622 QSLVALVRARRALLEQTLQRAE--------FLRNCEEEEAWLKECGQRVGNAALGRDLSQ 673
Query: 1327 VEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXX 1506
+ A +KH+A+E ++ ++ Q ER E V
Sbjct: 674 IAGALQKHKALEAEVHRHQAVCVDLVRRGRDLSARRPPTQPDPGERAEAVQGGWQLLQTR 733
Query: 1507 XXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLE-- 1680
R RL+ ++ + + F +S L G E LL++H LE
Sbjct: 734 VVGRGARLQTALLVLQYFADAAEAASWLRERRSSLERASCGQDQAAAETLLRRHVRLERV 793
Query: 1681 -----SDINIIGERVNNSIAQAQRF-------------RNPD---------GPDGSGYK- 1776
+++ + E+ + A+A F RNP GP G +K
Sbjct: 794 LRAFAAELRRLEEQGRAASARASLFTVNSALSPPGESLRNPGPWSEASCHPGP-GDAWKM 852
Query: 1777 --PVEP------GTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGI 1932
P EP TI + D L + Y+ L LA R+ RLE+ L F EL+ +
Sbjct: 853 ALPAEPDPDFDPNTILQTQDHLSQDYESLRALAQLRRARLEEAMALFGFCSSCGELQLWL 912
Query: 1933 KEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDN 2112
++Q +L D + V L K++N L + + S ++L+ S
Sbjct: 913 EKQTVLLQRVQPQADTLEVMQL--KYENFLTALAVGKGLWAEVSSSAEQLRQRYPGNSTQ 970
Query: 2113 IPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGK 2292
I + E+ +L+ L + +LA VE F + L D L + + G
Sbjct: 971 IQRQQEELSQRWGQLEALKREKAVQLAHSVEVCSFLQECGPTQVQLRDVLLQLEALQPGS 1030
Query: 2293 DEGT--VQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKA 2466
E T L +K V + F Q + V K E P A P ++ +++T
Sbjct: 1031 SEDTRHALQLAQKKTLVLERRVYFLQSVVV---KVEE-PGYAESQP-LQGQVETLQGLLK 1085
Query: 2467 ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFD 2646
+++ R +R + + ++ + W + L + D+ + +
Sbjct: 1086 QVQEQVAQRARRQAETQARQSFLQESQQLLLWAESVQAQLRSKEVSVDVASAQRLLREHQ 1145
Query: 2647 TLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELE 2826
L +++ + ++ ++ ++ + ++ P+S ++ + L + +L+ + +Q++ L+
Sbjct: 1146 DLLEEIHLWQERLQQLDAQSQPMAALDCPDSQEVPNTLRVLGQQGQELKVLWEQRQQWLQ 1205
Query: 2827 RAHRLETF--RID-----CQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDL 2985
L+ F +D C W+ D L D+ + L ++ R L
Sbjct: 1206 EGLELQKFGREVDGFTATCANHQAWLH--------LDNLGEDVREALSLLQQHREFGRLL 1257
Query: 2986 GAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQ 3165
+ + ++L + + + + A +RE ++ I W L + + +L + LQ
Sbjct: 1258 STLGPRAEALRAHGEKLVQSQHPAAHTVREQLQSIQAQWTRLQGRSEQRRRQLLASLQLQ 1317
Query: 3166 RFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG 3345
+ +D+ W+ + +A+ E + Q L +H A E+ + ++ +G
Sbjct: 1318 EWKQDVAELMQWM-EEKGLMAAHEPSGARRNILQTLKRHEAAESELLATRRHVEALQQVG 1376
Query: 3346 DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
+ + Q ++ RL GL+ WE L R R L Q + LR + A+ L
Sbjct: 1377 RELLSRRPCGQ-EDIQTRLQGLRSKWEALNRKMTERGDELQQAGQQEQLLRQLQDAKEQL 1435
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
Q E L + Q L ++ KRHQ + K+ A+ + ++
Sbjct: 1436 EQLEGALQSSETGQDLRSSQRLQKRHQQLESESRTLAAKMAALASMAHGMAA-SPAILEE 1494
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
K R ++ +G + + L+ ++ L QF + W+ E M +Y +
Sbjct: 1495 TQKHLRRLELLQGHLAIRGLQ----LQASVELHQFCHLSNMELSWVAEHMPHGSPTSYTE 1550
Query: 3886 A-KTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDE 4062
S +H+ Q E+ A++ ++ ++ + +L I Q +EL W E
Sbjct: 1551 CLNGAQSLHRKHKELQVEVKAHQGQVQRVLSSGRSLAASGHPQAQHIVEQCQELEGHWAE 1610
Query: 4063 LEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHL 4242
LE+ E + Q L A Q Y +++++ W + ++ D D + K
Sbjct: 1611 LERACEARAQCLQQAVTFQQYFLDVSELEGWVEEKRPLVSSRDYGRDEAATLRLINKHQA 1670
Query: 4243 IETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALER 4422
++ E+ ++ E + + RL +EQL+ LQ R + LE
Sbjct: 1671 LQEELAIYWSSMEELDQTAQTLTGPEVPEQQRVVQERL--REQLRALQELAATRDRELEG 1728
Query: 4423 KKAAFQFGRDVDDEKLWISERLVLAK-AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWIN 4599
+F R+ +D + W++ + AK ++LGE L ++++ +
Sbjct: 1729 TLRLHEFLREAEDLQGWLASQKQAAKGGESLGEDPEHALHLCTKFAKFQHQVEMGSQRVA 1788
Query: 4600 QICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGE 4779
+ L++ GH+ GP ++ Q+L++AW EL E + R L ++E + D E
Sbjct: 1789 ACRLLAESLLERGHSAGPMVRQRQQDLQTAWSELWELTQARGHALRDTETTLRVHRDLLE 1848
Query: 4780 AEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE-K 4956
+ E+ + + +D + Q++ H+ L+ ++ ++ L A + +
Sbjct: 1849 VLTQVQEKAT-SLPNNVARDLCGLEAQLRSHQGLERELVGTERQLQELLETAGRVQKLCP 1907
Query: 4957 SPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAG 5136
P +Q RQ + + +A LQ + D W A
Sbjct: 1908 GPQAHAVQQRQQAVTQAWAVLQRRMEQRRAQLERARLLARFRTAVRDYASWAARVRQDLQ 1967
Query: 5137 SQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDS 5316
+E+ Q+ + Q + E G L+ G PT
Sbjct: 1968 VEESSQEPSSGPLKLSAHQWLRAELEAREKLWQQATQLGQQALLAAG---TPT------- 2017
Query: 5317 LNEAWENLLELMDTRAQI----------LEASRLLHKFYHDCRDCLSRIM--EKTHAMPD 5460
E E L L D R Q+ L+A + F +C L I+ ++
Sbjct: 2018 -KEVQEELRALQDQRDQVYQTWARKQERLQAEQQEQLFLREC-GRLEEILAAQEVSLKTS 2075
Query: 5461 DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVV 5640
LG V L RKH+ +LK + A ++ A + LR D+ + R V
Sbjct: 2076 ALGSSVEEVEQLIRKHEVFLKVLTAQDKKEAALRERLKTLRRPRVRDRLPILLQRRMRV- 2134
Query: 5641 KAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLM 5820
+ L ++R L + + F W+ +++ P D+ +
Sbjct: 2135 ------KELAESRGHALHASLLMASFTQAATQAEDWIQAWAQQLKEPVPPGDLRDKLKPL 2188
Query: 5821 NNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRW 6000
HQ+ +AE+ A EE + G LL + H + E+ ++L L ++ + R
Sbjct: 2189 LKHQAFEAEVQAHEEVMTSVAKKGEALLAQSHPRAGEVSQRLQGLRKHWEDLRQAMALRG 2248
Query: 6001 EYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQE 6180
+ L+ +F + +AE+W+ +E + + G++LE ++L ++ F ++
Sbjct: 2249 QELEDRRNFLEFLQRVDLAEAWIQEKEVKMNVGDLGQDLEHCLQLRRRLREFRGNSAGDT 2308
Query: 6181 ERFLALEKLTTFELKETQHREEETAK 6258
+ ++ L + ++R+ E K
Sbjct: 2309 VGDACIRSISDLSL-QLKNRDPEEVK 2333
Score = 158 bits (399), Expect = 2e-36
Identities = 178/963 (18%), Positives = 375/963 (38%), Gaps = 4/963 (0%)
Frame = +1
Query: 1096 PFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLT 1275
PF +++A + + SLE A E +L L++ L Q F E E WL
Sbjct: 2542 PFSSDIRQVLAGLEQELSSLEGAWQEHQLQLQQALELQ--------LFLSSVEKMERWLC 2593
Query: 1276 ENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKI 1455
+ ++ + + L+ +E KH+ +E D+ + + +
Sbjct: 2594 SKEDSLASEGLWDPLAPMEPLLWKHKMLEWDLEVQAGKISALEATARGLHQGGHPEAQSA 2653
Query: 1456 NERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAH 1635
R + + RR RLE +Q + + L ++L A
Sbjct: 2654 LGRCQAMLLRKEALFRQAGTRRHRLEELRQLQAFLQ-------DSQEVAAWLREKNLVAL 2706
Query: 1636 LMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDV 1815
+ D A L+ N E ++ S+ Q Q + G P I ER +
Sbjct: 2707 EEGLLDTAMLPAQLQKQQNFQAE-LDASMHQQQELQREGQRLLQGGHPASE-AIQERLEE 2764
Query: 1816 LQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSH 1995
L + EL D + ++ +L+ + + ELE+ ++ E L + G+ + V
Sbjct: 2765 LGALWGELQDNSQKKVAKLQKACEALRLRRSMEELENWLEPIEVELRAPTVGQALPGVGE 2824
Query: 1996 LLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSAS 2175
LL + E + + + L + E + ++ + + L+E
Sbjct: 2825 LLGTQRELEAAVDKKARQAEALLGQAQAFVREGHCLAQDVEEQARRLLQRFKSLREPLQE 2884
Query: 2176 RKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQN 2355
R+ L +FF DAD+ ++ + L + +++D G+ V+ L ++H ++ E+ +
Sbjct: 2885 RRTALEARSLLLKFFRDADEEMAWVQEKLPLAAAQDYGQSLSAVRHLQEQHQNLESEMSS 2944
Query: 2356 FDQHIKVLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKL 2532
+ +V+ L Q ++ R+ K A L + R+ L A +
Sbjct: 2945 HEALTRVVLGTGYKLVQAGHFAAHEVAARVQQLEKAMAHLRAEAARRRLLLQQAQEAQQF 3004
Query: 2533 YSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
++ SW+ E+G +L + G E + + R + ++D++ ++ + A
Sbjct: 3005 LTELLEAGSWLAERGHVLDSEDMGHSAEATQALLRRLEATKRDLEAFSPRIERLQQTAAL 3064
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
L + ++P S +L + + A+L + + + L+ +L + W+ K
Sbjct: 3065 LESRKNPESPKVLAQLQAVREAHAELLRRAEARGHGLQEQLQLHQLERETLLLDAWLTTK 3124
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAI-QAKLDSLHKEADDIERERPQEAQAI 3069
E D DL GV L+ + +++ ++ QAK+ +L K A +ER P+ I
Sbjct: 3125 AATAESQD-YGQDLEGVKVLEEKFDAFRKEVQSLGQAKVYALRKLAGTLERGAPRRYPHI 3183
Query: 3070 REDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQS 3249
+ RI W+ L++ ++ L A ++ F + Q + + E+ S
Sbjct: 3184 QAQRSRIEAAWERLDQAIKARTENLAAAHEVHSFQQAAAELQGRMQEKTALMKGEDGGHS 3243
Query: 3250 LAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEE 3429
L+ L QH + E++ ++ +++ R+ Q + LA +QE W
Sbjct: 3244 LSSVRTLQQQHRRLERELEAMEKEVARLQTEACRLGQ-----LHPAAPGGLAKVQEAWAT 3298
Query: 3430 LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQD 3609
LQ R L+Q FL ++ +++ + +++ + + AE L +H++
Sbjct: 3299 LQAKAQERGQWLAQAAQGHAFLGRCQELLAWAQERQELASSEELAEDVAGAEQLLGQHEE 3358
Query: 3610 FITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKD 3789
+ + + + G QL + H+ + ++ + + ++ R E ++ +
Sbjct: 3359 LGQEIRECRLQAQDLRQEGQQLVDNSHFMSAEVTECLQELEGRLQELEEAWALRWQRCAE 3418
Query: 3790 ALSLQQFLSDCDELREWIE--EKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLD 3963
+ LQ+ ++ W+ E ++ D + + RHQ + LAA +E+
Sbjct: 3419 SWGLQKLRQRLEQAEAWLACWEGLLLKPDYGH-SVSDVELLLHRHQDLEKLLAAQEEKFA 3477
Query: 3964 QLK 3972
Q++
Sbjct: 3478 QMQ 3480
>gi|31209523|ref|XP_313728.1| ENSANGP00000017034 [Anopheles gambiae]
gi|21297077|gb|EAA09222.1| ENSANGP00000017034 [Anopheles gambiae str.
PEST]
Length = 4091
Score = 830 bits (2143), Expect = 0.0
Identities = 565/2124 (26%), Positives = 1012/2124 (47%), Gaps = 79/2124 (3%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGER 255
FE RIK L +ER +QKKTFTKW+NS LV+ +V DL++D+ DG LL+LL ++SGE+
Sbjct: 27 FENERIKTLQEERLHIQKKTFTKWMNSFLVKAKMEVDDLFIDLADGIKLLKLLEIISGEK 86
Query: 256 LPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQI 435
L KP G+MR+H +ENV K L FL + V LE++G+ DIVD N RL LGLIWTIILRFQI
Sbjct: 87 LGKPNSGRMRVHKIENVNKSLAFLHTK-VRLESIGAEDIVDHNPRLILGLIWTIILRFQI 145
Query: 436 QDITF---EDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHR 606
Q+I E+ ++ E +SAK+ALLLWCQ KT GY +V++ +F+ SWR GL FNALIH HR
Sbjct: 146 QEIEIDVDEENESSEKKSAKDALLLWCQRKTHGYQHVHITDFTNSWRSGLGFNALIHSHR 205
Query: 607 PDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHY 786
PDL DY++L + NL AFD AE +LG+ + LDAED++ +PDEKSI+TYV +YYH
Sbjct: 206 PDLFDYNSLMPGRNIENLNHAFDVAERELGIPQLLDAEDIDTARPDEKSILTYVASYYHT 265
Query: 787 FNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEG 966
F ++K + GKRI ++N+LM+ DK ++E L ++LL WI AK L +R+F N++EG
Sbjct: 266 FARMKSEQKGGKRIANIVNKLMDADKKKMQFEHLITNLLSWIRAKTVELEKRNFPNSVEG 325
Query: 967 VQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAW 1146
+Q +L F +YRT EKPPK+ E+ E+E L F + + +++ NQ + P++GK+I DI +AW
Sbjct: 326 IQGELLAFKEYRTVEKPPKYKERSEIEALYFHVNTLLKSLNQPHYTPQDGKMINDIEKAW 385
Query: 1147 QSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSS 1326
Q LE AEH RE+ L++EL+RQEKLEQL +F +K+ +RE +L E ++++ +G L
Sbjct: 386 QRLENAEHNREVALRDELLRQEKLEQLNFKFEKKSVLREGYLNEMIQVLTDPRYGPALRQ 445
Query: 1327 VEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXX 1506
V+A KKHEAI DI A +R NYH + ++ +R+ V
Sbjct: 446 VDATVKKHEAISADILARADRFNDLTDMCNELHQENYHGKDRVKKRELEVITKWKELLEL 505
Query: 1507 XXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESD 1686
+++L ++ + ++++ SED+G HL+ VE+LLQ H+LLE
Sbjct: 506 LENHKLKLSQMSSLMNLLREIDATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQ 565
Query: 1687 INIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKR 1866
+ +GE + Q + F+ D D S +D + L K Y+ELL ++A R+
Sbjct: 566 VTTLGETQRRYVRQGEAFKRGDYKDTS--------QLDAKLAELAKLYEELLAMSAARRA 617
Query: 1867 RLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEK 2046
RL++ + QF D E + +++++ + T +D+ V L KHK E+ ++ +
Sbjct: 618 RLDEARDFYQFVEDHENEEGWLVDKQRICKAGITAKDLRAVMSLQQKHKALEDEMKVRKP 677
Query: 2047 YLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTD 2226
+++ +GK+L + ++ ++ ++++ L++L RK +L E YQ++ D
Sbjct: 678 KSNQITEAGKKLIVDKHSRMSDVQGKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYAD 737
Query: 2227 ADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL-- 2400
A++ D +L + + +++S+D G DE + Q LL++H D+ EL + I L+ +AE L
Sbjct: 738 ANEADSWLNEKMALVASDDFGVDEPSAQALLQRHRDLQGELNAYSGDILNLNQQAEKLIK 797
Query: 2401 ------------------------------PQEAREHPDIRQRLDTTLKQKAELENLSQL 2490
P+E E + + T+ + L ++ L
Sbjct: 798 AGICTLDLSAEPEPVQEMEQEEWVNETRLVPKEVWEDEPVERLEHRTVTENKLLPHVKAL 857
Query: 2491 RK---QRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVE-------IMKHR 2640
+ Q + A + + ++V+ W K VP ++E+E + K
Sbjct: 858 YRFEGQNMKVAKGDVMILQNKNNVDWWNVRKLDGTEGFVPANYVKEIEPRPVPCLVRKAE 917
Query: 2641 FDTLEQDMKN-------------QEAKVTNVNDLARQLLNVEH----PNSDDILHRQNKL 2769
+ Q +K + AKV+ + L ++ + ++D + RQ +
Sbjct: 918 KVKVMQKVKKTILVKEVIQVKRVRPAKVSQMKPLVKRRAKGDESSAVDSNDSVDKRQKHI 977
Query: 2770 NARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMK 2949
N + QL+D+ +++R LE + L F +C + WI+DK ++L T+D G ++
Sbjct: 978 NGTYDQLQDLAERRRALLEDSICLFRFYRECDDFEKWIKDKEKMLR-----TDDPKGSVE 1032
Query: 2950 LQRR-LSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVR 3126
RR DL A +++++ + +D R+ + ++ ++IHQ+W+ LN
Sbjct: 1033 TARRQFETFVNDLSASSKRVEAIDSDVEDFVRQGHSQLDKVKARQRQIHQMWEHLNYLKG 1092
Query: 3127 EHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEID 3306
+ E L+ A ++ F R + W+ Q+ + E L + L +H + E+
Sbjct: 1093 QKEKSLEGASSVELFYRTCEEAIDWMNEKMTQLDTAEVGPDLKTVQALQRRHENLERELA 1152
Query: 3307 GYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQ 3486
E ++ +G+ V ++ + + ++ +Q W+++Q R+ L + Q
Sbjct: 1153 PVKEKVSRVNLLGNTV-KNSYPSERDNVSEKQRDIQNLWQKVQEKAKERRSRLENAVGQQ 1211
Query: 3487 MFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFG 3666
+F K +++ N LA ++ + +E AE LK+H+D ++A+D++ + G
Sbjct: 1212 IFNNSTKALLNWIAECNNQLAAEETARDVETAEKLLKKHKDLGEDINAHDDEFVQLAKLG 1271
Query: 3667 DQLCQ------DGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDE 3828
Q+ + + H A+KI K GA K KKL+ + LQ F + D+
Sbjct: 1272 QQIIERNPALTEDHEMANKIAKLEAERQRLHGAWLAKE----KKLQQCIELQIFNREADK 1327
Query: 3829 LREWIE-EKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
+ + + D+ + + RH F++ L A + L A L +
Sbjct: 1328 IDATTKSHEAYLEYDDLGNSLDDVEAIMKRHIDFENSLGAQDKILKNFSEGADRLIRNN- 1386
Query: 4006 EYHGT-IDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMT 4182
Y+ T ID + ++ + + +++ +++ L + Q + + D+ W + ++
Sbjct: 1387 HYNATYIDDRRGQVLARRERVKELAQKRRNALQASKDFQKFSSDVDDLNRWLAD-KTKIA 1445
Query: 4183 REDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAV 4362
++ DL+ + +QK E E+ + + + + A+
Sbjct: 1446 SDESYKDLSNLPRKLQKHKAFERELRANEGQLRMVNKEGESLIKTN-NRAGEVSETLAAI 1504
Query: 4363 QEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRL 4542
+ + L A D+ + LE+ + R ++D K E +++ +G L C L
Sbjct: 1505 NQNWKDLVATSLDKGRRLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDLRSCKEL 1564
Query: 4543 QKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDR 4722
Q+L N+I E + ++ G+E+ EGH + + + ++L++ + LK + R
Sbjct: 1565 MNKHQVLENDIALWEQKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPARQR 1624
Query: 4723 KGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKF 4902
+ L ES + H+F+++ W++E + G++ ++ KKH++L+++I+
Sbjct: 1625 RDALDESLRFHKFVFELDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEIEGH 1684
Query: 4903 ADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALH 5082
I T A + + P +++ +EK +A LQ+
Sbjct: 1685 QPMINKTLTSAENLINQNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQYL 1744
Query: 5083 REIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDT 5262
+ ++ W+ ++ V S + G+D + L + + + + S V+
Sbjct: 1745 SDAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIELELDTY-SGIVSEMGHTASA 1803
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
+I H D+ IA + + + ++L L R L S H+++ + + I E+
Sbjct: 1804 MIAAKHPDSKVIAAKQQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIKEQ 1863
Query: 5443 THAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
A+ +D G D + L K + I E+ Q E A +L G +I
Sbjct: 1864 EQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGG-DSPYVSEIE 1922
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
R+ + AW+HL DAR +L ++ +F + L + + K S E KD+
Sbjct: 1923 KRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFRIQD-KNAALSSELGKDL 1981
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMM 5979
+ L H++ + E+ E + D L + + K + E+ ++
Sbjct: 1982 NSALALARKHEAFENELVPLEAQLQVLVD---DSLRLQTKYPGDNAK---AIAAEQENVI 2035
Query: 5980 RRWED-------RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
+ W R + L ++ F SW L ++E+ + L
Sbjct: 2036 QYWNVLKEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALK 2095
Query: 6139 KKHEAFEKSAFAQEERFLALEKLT 6210
+H+A A+E+ F L +L+
Sbjct: 2096 IQHDAIYGEIEAREQTFRELNELS 2119
Score = 612 bits (1578), Expect = e-173
Identities = 442/1757 (25%), Positives = 805/1757 (45%), Gaps = 73/1757 (4%)
Frame = +1
Query: 1213 KLEQLAARFNRKAEMRETWLTEN--QRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEE 1386
KL Q+++ N E+ T T Q + ++ G L VE + H +E + E
Sbjct: 512 KLSQMSSLMNLLREIDATMTTIKALQAQFASEDVGPHLLGVEELLQAHSLLELQVTTLGE 571
Query: 1387 RXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHX 1566
+Y D ++++ + + ARR RL+ + + F
Sbjct: 572 TQRRYVRQGEAFKRGDYKDTSQLDAKLAELAKLYEELLAMSAARRARLDEARDFYQ-FVE 630
Query: 1567 XXXXXXXXXXIKSRLLSEDLGAH-LMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFR 1743
K R+ + A L V L QKH LE ++ + + +N I +A +
Sbjct: 631 DHENEEGWLVDKQRICKAGITAKDLRAVMSLQQKHKALEDEMKVRKPK-SNQITEAGKKL 689
Query: 1744 NPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELE 1923
D K + + D LQ+ +K L DL RKR+LED Q++ D E +
Sbjct: 690 IVD-------KHSRMSDVQGKIDSLQEHWKALEDLVDLRKRQLEDAAEAYQYYADANEAD 742
Query: 1924 HGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLR-------DLEKYLDRLDVSG--- 2073
+ E+ +++S D G D + LL +H++ + L +L + ++L +G
Sbjct: 743 SWLNEKMALVASDDFGVDEPSAQALLQRHRDLQGELNAYSGDILNLNQQAEKLIKAGICT 802
Query: 2074 ----------KELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFT 2223
+E++ E + P+ + + +L+ + + + L Y+F
Sbjct: 803 LDLSAEPEPVQEMEQEEWVNETRLVPKEVWEDEPVERLEHRTVTENKLLPHVKALYRFEG 862
Query: 2224 DADDVDRYLYDTLRVMSSED---VGKDEGT----------------VQLLLKKHDDVHDE 2346
V + L+ ++ D V K +GT V L++K + V
Sbjct: 863 QNMKVAKGDVMILQNKNNVDWWNVRKLDGTEGFVPANYVKEIEPRPVPCLVRKAEKVK-V 921
Query: 2347 LQNFDQHI---KVLHAKAESLPQEAREHPDIRQRL-----------DTTLKQKA------ 2466
+Q + I +V+ K + ++ P +++R D+ K++
Sbjct: 922 MQKVKKTILVKEVIQVKRVRPAKVSQMKPLVKRRAKGDESSAVDSNDSVDKRQKHINGTY 981
Query: 2467 -ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRF 2643
+L++L++ R+ L D++ L++ Y + D E WI +K K+L T P +E + +F
Sbjct: 982 DQLQDLAERRRALLEDSICLFRFYRECDDFEKWIKDKEKMLRTDDPKGSVETA---RRQF 1038
Query: 2644 DTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNEL 2823
+T D+ +V ++ + H D + RQ +++ W L + QK L
Sbjct: 1039 ETFVNDLSASSKRVEAIDSDVEDFVRQGHSQLDKVKARQRQIHQMWEHLNYLKGQKEKSL 1098
Query: 2824 ERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAK 3003
E A +E F C+E + W+ +K L+ ++ + DL V LQRR +ER+L ++ K
Sbjct: 1099 EGASSVELFYRTCEEAIDWMNEKMTQLDTAE-VGPDLKTVQALQRRHENLERELAPVKEK 1157
Query: 3004 LDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDL 3183
+ ++ + ++ P E + E + I +W + +K +E ++L+ A Q F
Sbjct: 1158 VSRVNLLGNTVKNSYPSERDNVSEKQRDIQNLWQKVQEKAKERRSRLENAVGQQIFNNST 1217
Query: 3184 DHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD 3363
W+ Q+A+EE + + AE+LL +H + E+I+ + +++ ++ +G ++ +
Sbjct: 1218 KALLNWIAECNNQLAAEETARDVETAEKLLKKHKDLGEDINAHDDEFVQLAKLGQQIIER 1277
Query: 3364 Q---TDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQ 3534
T+ M ++A L+ + L W ++ L Q + LQ+F R+A + +
Sbjct: 1278 NPALTEDHEM--ANKIAKLEAERQRLHGAWLAKEKKLQQCIELQIFNREADKIDATTKSH 1335
Query: 3535 ENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHK 3714
E YL DD+ SL+ E +KRH DF ++ A D+ ++ D+L ++ HY
Sbjct: 1336 EAYLEYDDLGNSLDDVEAIMKRHIDFENSLGAQDKILKNFSEGADRLIRNNHY------- 1388
Query: 3715 KARNIDERRG---ANREKAQEVLKKLKDALS----LQQFLSDCDELREWIEEKMIRAQDE 3873
A ID+RRG A RE+ +E+ +K ++AL Q+F SD D+L W+ +K A DE
Sbjct: 1389 NATYIDDRRGQVLARRERVKELAQKRRNALQASKDFQKFSSDVDDLNRWLADKTKIASDE 1448
Query: 3874 TYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQ 4053
+Y+D + K +H+AF+ EL AN+ +L + +L G + + +
Sbjct: 1449 SYKDLSNLPRKLQKHKAFERELRANEGQLRMVNKEGESLIKTNNRA-GEVSETLAAINQN 1507
Query: 4054 WDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQK 4233
W +L T+ +KG++L A Q+ + + I D K +L++ + + DL + M K
Sbjct: 1508 WKDLVATSLDKGRRLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDLRSCKELMNK 1567
Query: 4234 QHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKA 4413
++E ++ Q + + NI+ +Q Q L+ P RR A
Sbjct: 1568 HQVLENDIALWEQKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPARQRRDA 1627
Query: 4414 LERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPW 4593
L+ +F ++D E WI+E L AK++ +G++L L K + L EI+ H+P
Sbjct: 1628 LDESLRFHKFVFELDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEIEGHQPM 1687
Query: 4594 INQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDC 4773
IN+ + + LI++ H ++ L AW +L+E +R L S KA Q+L D
Sbjct: 1688 INKTLTSAENLINQNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQYLSDA 1747
Query: 4774 GEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE 4953
GE E W+ E+ + + G+D S + KH+ ++ ++D ++ + + A +
Sbjct: 1748 GEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTASAMIAA 1807
Query: 4954 KSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVA 5133
K P ++ I +Q IEK+ LQ + E +L QWI ++E
Sbjct: 1808 KHPDSKVIAAKQQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIKEQEQAV 1867
Query: 5134 GSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKD 5313
S++ G DYEH+ +LQ +F E +G+ER + LIG I ++
Sbjct: 1868 NSEDYGHDYEHLLILQNKFDDLKHRIE-VGAERFNQCENFAKKLIGGDSPYVSEIEKRQE 1926
Query: 5314 SLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGA 5493
L+ AW++LLE +D R + L A+ +H+F+ D + L RI +K A+ +LG+D +S A
Sbjct: 1927 LLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFRIQDKNAALSSELGKDLNSALA 1986
Query: 5494 LSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCD 5673
L+RKH+ + ++ + Q+ + D+ L+ Y GD A I + + V++ W L+
Sbjct: 1987 LARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVLKEKSA 2046
Query: 5674 ARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEID 5853
R +L + DL F+ VRDL+ W ++ + ++E D +G L H ++ EI+
Sbjct: 2047 LRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKIQHDAIYGEIE 2106
Query: 5854 AREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQ 6033
ARE+ F L ++ HYA++E+E+K L ERA++ + + L+ ++++
Sbjct: 2107 AREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQKIDLFC 2166
Query: 6034 FARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTT 6213
F RDA V ++ QE L S ++G+ +E +K+HEAFEK Q+E+ L++
Sbjct: 2167 FMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVKRHEAFEKLIQTQDEKVAILQEHGR 2226
Query: 6214 FELKETQHREEETAKRR 6264
+L E H + E +RR
Sbjct: 2227 -KLVEQNHYDSENIRRR 2242
Score = 417 bits (1072), Expect = e-114
Identities = 382/1836 (20%), Positives = 752/1836 (40%), Gaps = 13/1836 (0%)
Frame = +1
Query: 847 LMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEF-NDYRTQEKPPK 1023
L+E+ + R+ D +WI K ++L + ++E +RQ F ND K
Sbjct: 994 LLEDSICLFRFYRECDDFEKWIKDKEKMLRTDDPKGSVETARRQFETFVNDLSASSK--- 1050
Query: 1024 FDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELI 1203
+E + ++ +R + + + + I++ W+ L + ++E L+
Sbjct: 1051 -----RVEAIDSDVEDFVRQGHSQ--LDKVKARQRQIHQMWEHLNYLKGQKEKSLEGA-- 1101
Query: 1204 RQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYE 1383
F R E W+ E + G DL +V+A ++HE +E ++ +
Sbjct: 1102 ------SSVELFYRTCEEAIDWMNEKMTQLDTAEVGPDLKTVQALQRRHENLERELAPVK 1155
Query: 1384 ERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFH 1563
E+ ++ ++E++ ++ RR RLE ++ Q +
Sbjct: 1156 EKVSRVNLLGNTVKNSYPSERDNVSEKQRDIQNLWQKVQEKAKERRSRLENAVGQQIFNN 1215
Query: 1564 XXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF- 1740
++L +E+ + E LL+KH L DIN + Q+
Sbjct: 1216 STKALLNWIAECNNQLAAEETARDVETAEKLLKKHKDLGEDINAHDDEFVQLAKLGQQII 1275
Query: 1741 -RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAE 1917
RNP E + + L+ + L ++++L+ L F + +
Sbjct: 1276 ERNP--------ALTEDHEMANKIAKLEAERQRLHGAWLAKEKKLQQCIELQIFNREADK 1327
Query: 1918 LEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESI 2097
++ K E L D G + V ++ +H + EN+L +K L L +
Sbjct: 1328 IDATTKSHEAYLEYDDLGNSLDDVEAIMKRHIDFENSLGAQDKILKNFSEGADRLIRNNH 1387
Query: 2098 PGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSS 2277
+ I R ++ ++KEL+ R+ L ++ +F +D DD++R+L D ++ S
Sbjct: 1388 YNATYIDDRRGQVLARRERVKELAQKRRNALQASKDFQKFSSDVDDLNRWLADKTKIASD 1447
Query: 2278 EDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLK 2457
E KD + L+KH EL+ + +++++ + ESL + ++ + L +
Sbjct: 1448 ESY-KDLSNLPRKLQKHKAFERELRANEGQLRMVNKEGESLIKTNNRAGEVSETLAAINQ 1506
Query: 2458 QKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKH 2637
+L S + +RL A + + +S +E L + G D+ + + +
Sbjct: 1507 NWKDLVATSLDKGRRLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDLRSCKELMN 1566
Query: 2638 RFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRN 2817
+ LE D+ E KV + ++ + H ++++I + KL A++A L+ Q+R+
Sbjct: 1567 KHQVLENDIALWEQKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPARQRRD 1626
Query: 2818 ELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQ 2997
L+ + R F + + WI + + S+ + +L L ++ +E ++ Q
Sbjct: 1627 ALDESLRFHKFVFELDTELQWINEHLPAAK-SEVIGQNLHQAQSLSKKHKKLEAEIEGHQ 1685
Query: 2998 AKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLR 3177
++ A+++ + E ++E + + W L ++ E KL+ + Q++L
Sbjct: 1686 PMINKTLTSAENLINQNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQYLS 1745
Query: 3178 DLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKM-RAMGDRV 3354
D + WL + S + + A +LL +H I E+D Y+ +M +
Sbjct: 1746 DAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTASAMI 1805
Query: 3355 TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQ 3534
D + + +Q+L +++ + LQR+ RQ L + L + ++ + E + +Q
Sbjct: 1806 AAKHPDSKVIAAKQQL--IEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIKEQ 1863
Query: 3535 ENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHK 3714
E + +D E + D ++ E+ F +L +I K
Sbjct: 1864 EQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDSPYVSEIEK 1923
Query: 3715 KARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKT 3894
+ + E+ KKL A + +F D E I++K E +D +
Sbjct: 1924 RQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFRIQDKNAALSSELGKDLNS 1983
Query: 3895 ITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP-EYHGTIDPQIEELATQWDELEK 4071
+ +H+AF++EL + +L L ++ L P + I + E + W+ L++
Sbjct: 1984 ALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVLKE 2043
Query: 4072 TTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIET 4251
+ + +L + Q ++ + D+ WAT L + E+ D + I
Sbjct: 2044 KSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKIQHDAIYG 2103
Query: 4252 EMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKA 4431
E+ + Q ++ A+ ++ +L + + ++ LE+K
Sbjct: 2104 EIEAREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQKID 2163
Query: 4432 AFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICN 4611
F F RD S + + + G+++ K + I + + +
Sbjct: 2164 LFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVKRHEAFEKLIQTQDEKVAILQE 2223
Query: 4612 NGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAW 4791
+G++L+++ H + ++++E+ Q++K+ R+ L + QF+ DC EA AW
Sbjct: 2224 HGRKLVEQNHYDSENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAEAGAW 2283
Query: 4792 MSEQELYMMQDERGKDEFST-KNQIKKHERLQ---SDIDKFADTIRALATKAHKFVEEKS 4959
++E++ + D S ++++KK ++LQ ++++ IR + K K + +K
Sbjct: 2284 INEKQKKLEADAHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLIAKKH 2343
Query: 4960 PLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGS 5139
+IQ ++ + + L + + ++D L WI DKE++ +
Sbjct: 2344 ECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEMMIHA 2403
Query: 5140 QENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSL 5319
E G+D EH L+ + D + +R+ N N D L+ + + +++
Sbjct: 2404 GETGRDLEHCNALRRKLDDVDSDM-RVDDQRIKNINQLADKLVSQDKVEGKNVQQRRENF 2462
Query: 5320 NEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDLGRDSSSVGAL 5496
N W++L + +L + +H F D D RI EK AM DD GRD +V AL
Sbjct: 2463 NNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIAVEAL 2522
Query: 5497 SRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDA 5676
RK + +D+ A+ +++ + E AA L D Y D A++I + E+ K W L+
Sbjct: 2523 KRKQEAIERDMTAVEQKIREHETSAAALADKYP-DNAINIVEKLDELRKQWNELQNASVK 2581
Query: 5677 RTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDA 5856
R L KF V++L LW +E+ + M+S P ++ E + H KAEID
Sbjct: 2582 RAEMLKQGYTAHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHHERKAEIDG 2641
Query: 5857 REENFNACISLGRDLLNRKHYAS---SEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEV 6027
R+ F G L+ +S +EK L L + W+ R+ L+ ++
Sbjct: 2642 RDLVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKGRFRGLKEAHQL 2701
Query: 6028 YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 6207
F A WL +E +L + + G + LIKKHEAFEK R LE+
Sbjct: 2702 QLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAFEK--LLHSNRIGELERF 2759
Query: 6208 TTFELKETQHREEETAKRRGPAHIGSPSRSTPAAET 6315
L E+ E + K+R A + + +AET
Sbjct: 2760 AEEILAESPF-EADVIKQRLYAVVSRKDKLLASAET 2794
Score = 371 bits (952), Expect = e-100
Identities = 382/1849 (20%), Positives = 770/1849 (40%), Gaps = 34/1849 (1%)
Frame = +1
Query: 820 KRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDY 999
K + + ++ K ++ + DL W+ K ++ ++ +++ L + R+L + +
Sbjct: 1408 KELAQKRRNALQASKDFQKFSSDVDDLNRWLADKTKIASDESYKD-LSNLPRKLQKHKAF 1466
Query: 1000 RTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERE 1179
+ + +G+L ++ +S ++ NN+ V + +A IN+ W+ L ++
Sbjct: 1467 ERELRA----NEGQLRMVNKEGESLIKTNNRAGEV---SETLAAINQNWKDLVATSLDKG 1519
Query: 1180 LVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAI 1359
L++ +++E NR E ++ E + GNDL S + KH+ +
Sbjct: 1520 RRLEQAALQREH--------NRYIEDSKSKFEELDHALQSKQVGNDLRSCKELMNKHQVL 1571
Query: 1360 ETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELS 1539
E DI +E++ + D I + + RR L+ S
Sbjct: 1572 ENDIALWEQKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPARQRRDALDES 1631
Query: 1540 MAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNS 1719
+ K SE +G +L + L +KH LE++I +N +
Sbjct: 1632 LRFHKFVFELDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEIEGHQPMINKT 1691
Query: 1720 IAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQF 1899
+ A+ N + P E + E + L+K + +L + +AER R+LE + + Q+
Sbjct: 1692 LTSAENLINQNHP--------ERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQY 1743
Query: 1900 WWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKE 2079
D E+E + E+ VL S+D GRD + + LL KHK E L + + +
Sbjct: 1744 LSDAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTASA 1803
Query: 2080 LQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDT 2259
+ P S I + I + L+ L+ R+ RL + +++F ++ ++++++ +
Sbjct: 1804 MIAAKHPDSKVIAAKQQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIKEQ 1863
Query: 2260 LRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL-PQEAREHPDIRQ 2436
+ ++SED G D + +L K DD+ ++ + A+ L ++ +I +
Sbjct: 1864 EQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDSPYVSEIEK 1923
Query: 2437 RLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIE 2616
R + L R+++L A +++ + DA I +K L++ + G+D+
Sbjct: 1924 RQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEALFRIQDKNAALSSEL-GKDLN 1982
Query: 2617 EVEIMKHRFDTLEQDMKNQEAKV-TNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLR 2793
+ + + E ++ EA++ V+D R N+ I Q + W L+
Sbjct: 1983 SALALARKHEAFENELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVLK 2042
Query: 2794 DMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMM 2973
+ + ++L + L+ F ++ ++W + L+ + ++ D +G L+ + +
Sbjct: 2043 EKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVS-DAAGATALKIQHDAI 2101
Query: 2974 ERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEA 3153
++ A + L++ +D + + A + E + L+ + + L++
Sbjct: 2102 YGEIEAREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQK 2161
Query: 3154 GDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKM 3333
DL F+RD + + ++S + Q++ + + +H A + I E +
Sbjct: 2162 IDLFCFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVKRHEAFEKLIQTQDEKVAIL 2221
Query: 3334 RAMGDR-VTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQ 3510
+ G + V Q+ D + +R+RL + E ++++ + R+ L+ L F+RD +
Sbjct: 2222 QEHGRKLVEQNHYDSEN--IRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAE 2279
Query: 3511 AEVMLSQQENYLAKDDIP----QSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLC 3678
A +++++ L D ++E +LK+ Q F ++AN+ +IR V G++L
Sbjct: 2280 AGAWINEKQKKLEADAHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLI 2339
Query: 3679 QDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEK-- 3852
H A +I + + + + + LK+A + +F + D+L WI +K
Sbjct: 2340 AKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEM 2399
Query: 3853 MIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQ 4032
MI A ET RD + + + S++ + +R+ + A L + +
Sbjct: 2400 MIHA-GETGRDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKNVQQR 2458
Query: 4033 IEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTT 4212
E +W L+ L A ++ + + D E + M+ +D DL
Sbjct: 2459 RENFNNKWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIA 2518
Query: 4213 VNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAP 4392
V +KQ IE +M Q I +PD NI +++Q LQ
Sbjct: 2519 VEALKRKQEAIERDMTAVEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWNELQNA 2578
Query: 4393 LDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNE 4572
R + L++ A +F +V + +LW +E + + + ++ DC + E
Sbjct: 2579 SVKRAEMLKQGYTAHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHHERKAE 2638
Query: 4573 IDNHEPWINQICNNGQELIDEGHANGPA---FEKKIQELRSAWQELKEAVKDRKGDLGES 4743
ID + + +G+ L+ E + EK ++ L + L ++ K R L E+
Sbjct: 2639 IDGRDLVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKGRFRGLKEA 2698
Query: 4744 EKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS--------DIDK 4899
+ F + W++ +E ++ D+ G+ + + IKKHE + ++++
Sbjct: 2699 HQLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAFEKLLHSNRIGELER 2758
Query: 4900 FADTIRA--------LATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXX 5055
FA+ I A + + + V K L + R+ +KL LQ
Sbjct: 2759 FAEEILAESPFEADVIKQRLYAVVSRKDKLLASAETRK---QKLQESLQ----------- 2804
Query: 5056 XXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFAR-DTENIG-SE 5229
R + ++ +W K +A + +Y LQ + Q+ A D E + S
Sbjct: 2805 ----LQQFLRSLYEVEKWTNQKMQIALDE----NYREPSNLQSKIQKHAAFDAELLANSG 2856
Query: 5230 RVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHD 5409
RV + ++LI H + + D + W+ L E + + L + F
Sbjct: 2857 RVTAVIEEGESLINAEHYASSLVQEQLDIVENEWQKLREASREKKERLAEAYEALLFQRS 2916
Query: 5410 CRDCLSRIMEKTHAM--PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELR 5583
D + M++ A +D GRD +SV L +KH D+A + QI+ A++
Sbjct: 2917 LED-FNNWMDEVEAQLSSEDYGRDLASVHNLLKKHDMLEADVAHHADTCEQIKATDAKM- 2974
Query: 5584 DGYAGDKALDIGSRESEVV--KAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDE 5757
+ D L ES +V K + L R L D+ L +F+ D LLW++E
Sbjct: 2975 --LSSDHFLKDELHESAMVTIKRYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLNE 3032
Query: 5758 VKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIE 5937
+ + S++ ++ V+ L HQ+L+AEI +E +A + G+ ++ HYA +IE
Sbjct: 3033 KEPQAASKDLGSSLTAVQSLQKKHQALEAEILIQEPIISALVQRGQQMIRDNHYAVEQIE 3092
Query: 5938 KKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNL 6117
++ +L ++ + R L +E QF +A AE WL ++P + S++YG++
Sbjct: 3093 RQCGQLQSKLVNLRHLTNVRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYGKDE 3152
Query: 6118 EETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRR 6264
+ L KK + ++ A + +E L + L+ H + E K +
Sbjct: 3153 DSVASLQKKLDGLQRELGAFKPTVEKIETLAS-GLQARGHFDSEKIKSK 3200
Score = 348 bits (894), Expect = 8e-94
Identities = 351/1833 (19%), Positives = 743/1833 (40%), Gaps = 43/1833 (2%)
Frame = +1
Query: 1132 INRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFG 1311
I + +SL++ +R+L L E L R E F AE+ E W+ E ++ V+ +++G
Sbjct: 1822 IEKMLKSLQRLAGQRQLRLMESLYRHEY-------FVESAEL-EQWIKEQEQAVNSEDYG 1873
Query: 1312 NDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXX 1491
+D + K + ++ I ER + ++I +R+E +
Sbjct: 1874 HDYEHLLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDSPYVSEIEKRQELLSNAWQ 1933
Query: 1492 XXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHA 1671
AR +L + I + FH K+ LS +LG L L +KH
Sbjct: 1934 HLLEQLDAREKKLHAAGEIHR-FHRDAAEALFRIQDKNAALSSELGKDLNSALALARKHE 1992
Query: 1672 LLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLA 1851
E+++ + ++ + + R + D + E + + +VL+++ +
Sbjct: 1993 AFENELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVLKEK-------S 2045
Query: 1852 AERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNL 2031
A R +L + L F V +L L + + D + L +H +
Sbjct: 2046 ALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKIQHDAIYGEI 2105
Query: 2032 RDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYY 2211
E+ L+ + + + + + + D KL +K L ++ +
Sbjct: 2106 EAREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQKIDLF 2165
Query: 2212 QFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKA 2391
F DA +D +SS D G+ VQ +K+H+ +Q D+ + +L
Sbjct: 2166 CFMRDAKVIDNISSGQEATLSSSDFGQTVEVVQDQVKRHEAFEKLIQTQDEKVAILQEHG 2225
Query: 2392 ESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWID 2568
L ++ + +IR+RL ++++ ++++L LR+Q+L +AL + D +WI+
Sbjct: 2226 RKLVEQNHYDSENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAEAGAWIN 2285
Query: 2569 EKGKLL---ATLVPGRDIEEVEIMK-HRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPN 2736
EK K L A G E ++ K + + ++ E ++ V D +L+ +H
Sbjct: 2286 EKQKKLEADAHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLIAKKHEC 2345
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
+ +I KL W L + + + L+ A + F + WI DK ++ +
Sbjct: 2346 AGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEMMIHAGE 2405
Query: 2917 ALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQ 3096
DL L+R+L ++ D+ ++ ++++ AD + + E + +++ + +
Sbjct: 2406 T-GRDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKNVQQRRENFNN 2464
Query: 3097 VWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLN 3276
W L + + L A ++ F RD+D + ++ ++ + L E L
Sbjct: 2465 KWKSLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIAVEALKR 2524
Query: 3277 QHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQ 3456
+ AI ++ + ++ + D + ++L L++ W ELQ R
Sbjct: 2525 KQEAIERDMTAVEQKIREHETSAAALADKYPDNAINIV-EKLDELRKQWNELQNASVKRA 2583
Query: 3457 HLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAND 3636
+L QG F + K+ E+ ++ + P ++ E Q++ H + +D D
Sbjct: 2584 EMLKQGYTAHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHHERKAEIDGRD 2643
Query: 3637 EKIRAVGMFGDQLCQDGHYAA---DKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQ 3807
R + G++L + ++ D + K RN+++ + + + LK+A LQ
Sbjct: 2644 LVFRDLQEHGERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKGRFRGLKEAHQLQL 2703
Query: 3808 FLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVR-HQAFQSELAANKERLDQLKHAAI 3984
F D++ EW+ K ++ ++ T ++ H+AF+ L +N R+ +L+ A
Sbjct: 2704 FKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAFEKLLHSN--RIGELERFAE 2761
Query: 3985 NLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQ 4164
+ + P I ++ + ++ D+L + E + QKL ++ + Q +++S+ ++++W Q
Sbjct: 2762 EILAESPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQESLQLQQFLRSLYEVEKWTNQ 2821
Query: 4165 LENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIK 4344
+ ++ ++ + + + +QK + E++ + + ++
Sbjct: 2822 -KMQIALDENYREPSNLQSKIQKHAAFDAELLANSGRVTAVIEEGESLINAEHYASSLVQ 2880
Query: 4345 AHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESL 4524
V+ + Q+L+ ++++ L A F R ++D W+ E +++ G L
Sbjct: 2881 EQLDIVENEWQKLREASREKKERLAEAYEALLFQRSLEDFNNWMDEVEAQLSSEDYGRDL 2940
Query: 4525 PDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELK 4704
H L K +L ++ +H QI +++ H + + L
Sbjct: 2941 ASVHNLLKKHDMLEADVAHHADTCEQIKATDAKMLSSDHFLKDELHESAMVTIKRYHSLH 3000
Query: 4705 EAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQ 4884
E R+ +L +S + HQFL D + W++E+E + G + ++ KKH+ L+
Sbjct: 3001 EPTTIRRDNLEDSLQLHQFLRDAEDELLWLNEKEPQAASKDLGSSLTAVQSLQKKHQALE 3060
Query: 4885 SDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXX 5064
++I I AL + + + + EQI+ + Q++ L+
Sbjct: 3061 AEILIQEPIISALVQRGQQMIRDNHYAVEQIERQCGQLQSKLVNLRHLTNVRRLRLLDAV 3120
Query: 5065 XXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGS--ERVA 5238
+ E ++ W+ +K+ + SQ+ G+D + V LQ++ R+ E++
Sbjct: 3121 ESQQFYAEANEAEFWLREKKPIISSQDYGKDEDSVASLQKKLDGLQRELGAFKPTVEKIE 3180
Query: 5239 NANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRD 5418
G L GH D+ I D + ++ L L R + L + L++F + D
Sbjct: 3181 TLASG---LQARGHFDSEKIKSKNDKIQYQFQELNRLAAEREKKLAEMKKLYEFVREIDD 3237
Query: 5419 CLSRI-MEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQV-AQIERDAAELRDGY 5592
I ++ T A ++ G D V L+ + ++++ ++ A ++ A + + A L +G
Sbjct: 3238 LQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFESFVSNLNANESRLTACVAKGEALLSEGN 3297
Query: 5593 AGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREM 5772
I ++ E + W L+ L AR L + F + + W++E +
Sbjct: 3298 PNRDT--IKAKRDETKQLWEELKDLVVARQEALAGARQVHVFDRTADETIAWVNEKISSV 3355
Query: 5773 NSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIK 5952
S++ D+ ++ L+ H++ +AE+ A +E + ++ + L + A IE K +
Sbjct: 3356 LSEDYGHDLETIQSLVRTHEAFEAELGAIKEQLESVVNEAQKLADTYPDAKEHIEVKRDE 3415
Query: 5953 LTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIK 6132
+E+ R R E L ++ + + +W+ + + + +++
Sbjct: 3416 TIEVWSELKDRTVQRKEKLTQAEQLQAYFDEYRDLMAWINEMLAKITAPDLAKDVAGAEA 3475
Query: 6133 LIKKH----EAFEKSAFAQEERFL----ALEKLTTFE--------LKETQHREEETAKRR 6264
LI KH E +K A ++ + L +++L +E LKE + E R+
Sbjct: 3476 LIDKHFLANEVQDKIAVLEQRKRLLDNTIVQRLEMYELNLDTQRFLKEAEDMESWIISRQ 3535
Query: 6265 GPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEG--------TLIRKHTYESLDRKAANR 6420
S E +D K A E TL+ + + L+ + A R
Sbjct: 3536 MQLKESKLGDSIAQVEDLLRKHEDFEKTVAAQEEKVLALKRITLLEQKFKKQLEAEQAAR 3595
Query: 6421 SWEK------LYAVLRQNELSFYKDPKHRDESV 6501
EK + L+Q E+ + + R E +
Sbjct: 3596 IAEKERIERERHEALKQKEVQRITEERRRREPI 3628
Score = 328 bits (841), Expect = 1e-87
Identities = 356/1734 (20%), Positives = 698/1734 (39%), Gaps = 33/1734 (1%)
Frame = +1
Query: 1267 WLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQ 1446
W+ E+ + G +L ++ +KKH+ +E +I ++ N+ ++
Sbjct: 1647 WINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEIEGHQPMINKTLTSAENLINQNHPER 1706
Query: 1447 AKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDL 1626
AK+ E ++ R +LELS+ Q+ + L S D
Sbjct: 1707 AKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQYLSDAGEIETWLGERNNVLRSSDY 1766
Query: 1627 GAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDER 1806
G LL KH ++E +++ V+ A PD I +
Sbjct: 1767 GRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTASAMIAAKHPDSK--------VIAAK 1818
Query: 1807 SDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVT 1986
+++K K L LA +R+ RL ++ +++ + AELE IKEQEQ ++S D G D
Sbjct: 1819 QQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELEQWIKEQEQAVNSEDYGHDYEH 1878
Query: 1987 VSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKEL 2166
+ L K + ++ + + ++ + K+L P I R + + L E
Sbjct: 1879 LLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDSPYVSEIEKRQELLSNAWQHLLEQ 1938
Query: 2167 SASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDE 2346
+R+++L E ++F DA + + D +SSE +GKD + L +KH+ +E
Sbjct: 1939 LDAREKKLHAAGEIHRFHRDAAEALFRIQDKNAALSSE-LGKDLNSALALARKHEAFENE 1997
Query: 2347 LQNFDQHIKVLHAKAESLPQEAREHPD----IRQRLDTTLKQKAELENLSQLRKQRLIDA 2514
L + ++VL +SL + + D I + ++ L+ S LR +L +
Sbjct: 1998 LVPLEAQLQVL--VDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVLKEKSALRNDQLHAS 2055
Query: 2515 LSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNV 2694
L + + SW L D +K + D + +++ +E +
Sbjct: 2056 CDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREQTFREL 2115
Query: 2695 NDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETV 2874
N+L+ ++ H + ++ + + L A+L ++K+ LE+ L F D +
Sbjct: 2116 NELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQKIDLFCFMRDAKVID 2175
Query: 2875 TWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQ 3054
+ L SD + V +R E+ + K+ L + + +
Sbjct: 2176 NISSGQEATLSSSD-FGQTVEVVQDQVKRHEAFEKLIQTQDEKVAILQEHGRKLVEQNHY 2234
Query: 3055 EAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASE 3234
+++ IR ++ I + + KL A +F+RD AW+ Q+++ E
Sbjct: 2235 DSENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAEAGAWINEKQKKL--E 2292
Query: 3235 EEPQSLAEAEQL------LNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQ 3396
+ S A A + L + A E++ +++R G+++ + + ++
Sbjct: 2293 ADAHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLIAKKHECAGE-IQD 2351
Query: 3397 RLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLE 3576
L L + W L +R L + ++ F + E + +E + + + LE
Sbjct: 2352 ELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEMMIHAGETGRDLE 2411
Query: 3577 QAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANRE 3756
++ D + M +D++I+ + D+L + ++ N + + + +
Sbjct: 2412 HCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKNVQQRRENFNNKWKSLQG 2471
Query: 3757 KAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQ-DETYRDAKTITSKFVRHQAFQS 3933
L A + F D D+ E I EKM+ D+T RD + + + +A +
Sbjct: 2472 ALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIAVEALKRKQEAIER 2531
Query: 3934 ELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANR 4113
++ A ++++ + + +A L D P+ I +++EL QW+EL+ + ++ + L
Sbjct: 2532 DMTAVEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWNELQNASVKRAEMLKQGYT 2591
Query: 4114 QQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEM------IKKAQH 4275
+ ++ +++ WA ++ M P + +Q H + E+ + Q
Sbjct: 2592 AHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHHERKAEIDGRDLVFRDLQE 2651
Query: 4276 IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDV 4455
D +E KA R +++ + L R + L+ F
Sbjct: 2652 HGERLVAENRESSVRNDHVE--KALR-NLEDLNKHLHDSWKGRFRGLKEAHQLQLFKEQA 2708
Query: 4456 DDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDE 4635
D W++ + +LGES L K + + H I ++ +E++ E
Sbjct: 2709 DQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAFEKLL--HSNRIGELERFAEEILAE 2766
Query: 4636 GHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYM 4815
++++ + S +L + + RK L ES + QFL E E W + Q++ +
Sbjct: 2767 SPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQESLQLQQFLRSLYEVEKW-TNQKMQI 2825
Query: 4816 MQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQ 4995
DE ++ + +++I+KH +++ + + A+ + + + + +Q +
Sbjct: 2826 ALDENYREPSNLQSKIQKHAAFDAELLANSGRVTAVIEEGESLINAEHYASSLVQEQLDI 2885
Query: 4996 IEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQM 5175
+E + L++ R ++D W+ + E S++ G+D V
Sbjct: 2886 VENEWQKLREASREKKERLAEAYEALLFQRSLEDFNNWMDEVEAQLSSEDYGRDLASVHN 2945
Query: 5176 LQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIA---LWKDSLNEA------ 5328
L ++ D VA+ D C+ + TDA ++ KD L+E+
Sbjct: 2946 LLKKHDMLEAD--------VAHHADTCEQIKA---TDAKMLSSDHFLKDELHESAMVTIK 2994
Query: 5329 -WENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKT-HAMPDDLGRDSSSVGALSR 5502
+ +L E R LE S LH+F D D L + EK A DLG ++V +L +
Sbjct: 2995 RYHSLHEPTTIRRDNLEDSLQLHQFLRDAEDELLWLNEKEPQAASKDLGSSLTAVQSLQK 3054
Query: 5503 KHQNYLKDIAAIGEQV--AQIERDAAELRDGYAGDKALD--IGSRESEVVKAWRHLRGLC 5670
KHQ +I I E + A ++R +RD + + ++ G +S++V +LR L
Sbjct: 3055 KHQALEAEIL-IQEPIISALVQRGQQMIRDNHYAVEQIERQCGQLQSKLV----NLRHLT 3109
Query: 5671 DARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEI 5850
+ R RL+D + +F + W+ E K ++SQ+ KD V L L+ E+
Sbjct: 3110 NVRRLRLLDAVESQQFYAEANEAEFWLREKKPIISSQDYGKDEDSVASLQKKLDGLQREL 3169
Query: 5851 DAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVY 6030
A + +L L R H+ S +I+ K K+ + E+ R +R + L + ++Y
Sbjct: 3170 GAFKPTVEKIETLASGLQARGHFDSEKIKSKNDKIQYQFQELNRLAAEREKKLAEMKKLY 3229
Query: 6031 QFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLT 6210
+F R+ + W+ Q S+EYG ++E +L + E+F + A E R A
Sbjct: 3230 EFVREIDDLQEWIEVQMTTAGSEEYGTDVEHVEQLTAQFESFVSNLNANESRLTACVAKG 3289
Query: 6211 TFELKE-TQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGT 6369
L E +R+ AKR + + A A GA+Q F+ T
Sbjct: 3290 EALLSEGNPNRDTIKAKRDETKQLWEELKDLVVARQEALA---GARQVHVFDRT 3340
Score = 315 bits (807), Expect = 1e-83
Identities = 339/1699 (19%), Positives = 685/1699 (39%), Gaps = 30/1699 (1%)
Frame = +1
Query: 1153 LEKAEHERELVLKEELIRQEKLEQLAAR--FNRKAEMRETWLTENQRLVSQDNFGNDLSS 1326
+ K E ER+ + L +++KL+Q FNR+A+ + ++ + D+ GN L
Sbjct: 1291 IAKLEAERQRLHGAWLAKEKKLQQCIELQIFNREADKIDATTKSHEAYLEYDDLGNSLDD 1350
Query: 1327 VEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXX 1506
VEA K+H E + A ++ N+++ I++R+ V
Sbjct: 1351 VEAIMKRHIDFENSLGAQDKILKNFSEGADRLIRNNHYNATYIDDRRGQVLARRERVKEL 1410
Query: 1507 XXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESD 1686
RR L+ S QK F K+++ S++ L ++ LQKH E +
Sbjct: 1411 AQKRRNALQASKDFQK-FSSDVDDLNRWLADKTKIASDESYKDLSNLPRKLQKHKAFERE 1469
Query: 1687 INIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKR 1866
+ R N R N +G + G + E + + +K+L+ + ++ R
Sbjct: 1470 L-----RANEG---QLRMVNKEG-ESLIKTNNRAGEVSETLAAINQNWKDLVATSLDKGR 1520
Query: 1867 RLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEK 2046
RLE + + + + +E + L S G D+ + L+ KH+ EN++ E+
Sbjct: 1521 RLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDLRSCKELMNKHQVLENDIALWEQ 1580
Query: 2047 YLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTD 2226
+ L +G+E+ E ++NI +++ LK + R++ L + +++F +
Sbjct: 1581 KVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLKTPARQRRDALDESLRFHKFVFE 1640
Query: 2227 ADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL-P 2403
D +++ + L SE +G++ Q L KKH + E++ I AE+L
Sbjct: 1641 LDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLEAEIEGHQPMINKTLTSAENLIN 1700
Query: 2404 QEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKL 2583
Q E +++ ++ K A+L+ S R ++L +L + SDA +E+W+ E+ +
Sbjct: 1701 QNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSLKAQQYLSDAGEIETWLGERNNV 1760
Query: 2584 LATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQN 2763
L + GRD + + + +E ++ V+ + A ++ +HP+S I +Q
Sbjct: 1761 LRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMGHTASAMIAAKHPDSKVIAAKQQ 1820
Query: 2764 KLNARWAQLRDMVDQKRNEL-ERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSG 2940
+ L+ + Q++ L E +R E F ++ E WI+++ + + D +D
Sbjct: 1821 LIEKMLKSLQRLAGQRQLRLMESLYRHEYF-VESAELEQWIKEQEQAVNSED-YGHDYEH 1878
Query: 2941 VMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKK 3120
++ LQ + ++ + + + A + I + + + W L ++
Sbjct: 1879 LLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDSPYVSEIEKRQELLSNAWQHLLEQ 1938
Query: 3121 VREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA-SEEEPQSLAEAEQLLNQHAAIRE 3297
+ E KL AG++ RF RD +A + A S E + L A L +H A
Sbjct: 1939 LDAREKKLHAAGEIHRFHRDA--AEALFRIQDKNAALSSELGKDLNSALALARKHEAFEN 1996
Query: 3298 EIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGL 3477
E+ + + R+ + + + W L+ R L
Sbjct: 1997 ELVPLEAQLQVLVDDSLRLQTKYPGDNAKAIAAEQENVIQYWNVLKEKSALRNDQLHASC 2056
Query: 3478 NLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVG 3657
+LQ FL + + L ++ A +H ++A ++ R +
Sbjct: 2057 DLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALKIQHDAIYGEIEAREQTFRELN 2116
Query: 3658 MFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDC---DE 3828
D + Q GHYAA ++ +K + + R + L+ + L F+ D D
Sbjct: 2117 ELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKKKILLEQKIDLFCFMRDAKVIDN 2176
Query: 3829 LREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPE 4008
+ E + + + + + + + RH+AF+ + E++ L+ L +
Sbjct: 2177 ISSGQEATL--SSSDFGQTVEVVQDQVKRHEAFEKLIQTQDEKVAILQEHGRKLVEQNHY 2234
Query: 4009 YHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTRE 4188
I ++ E+ + +++ + QKL +A +++ A+ W + + ++ +
Sbjct: 2235 DSENIRRRLREIVERRQKVKDLCALRRQKLANALLYAQFIRDCAEAGAWINEKQKKLEAD 2294
Query: 4189 DQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENI--KAHRLA- 4359
+ A + + +KK Q D D+ E + K H A
Sbjct: 2295 AH-------SYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVRDKGEKLIAKKHECAG 2347
Query: 4360 -VQEQLQRLQA-------PLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLG 4515
+Q++L +L L R + L+ + +F +D + WI ++ ++ A G
Sbjct: 2348 EIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEAWIRDKEMMIHAGETG 2407
Query: 4516 ESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQ 4695
L C+ L++ L + +++ + I I +L+ + G +++ + + W+
Sbjct: 2408 RDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEGKNVQQRRENFNNKWK 2467
Query: 4696 ELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHE 4875
L+ A+ + L + + H F D + ++E+ L M D+ G+D + + +K E
Sbjct: 2468 SLQGALSRYRDLLAGAYEIHVFNRDVDDTAERIAEKMLAMSVDDTGRDLIAVEALKRKQE 2527
Query: 4876 RLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXX 5055
++ D+ IR T A ++ I + ++ K + LQ+
Sbjct: 2528 AIERDMTAVEQKIREHETSAAALADKYPDNAINIVEKLDELRKQWNELQNASVKRAEMLK 2587
Query: 5056 XXXXXYALHREIDDLLQWIADKEVVAGSQENG---QDYE-HVQMLQERFQQF------AR 5205
+ + +L W + S N D E +Q+ ER + R
Sbjct: 2588 QGYTAHKFTANVKELELWANEMIKRMDSASNPATIADCEAQIQLHHERKAEIDGRDLVFR 2647
Query: 5206 DTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASR 5385
D + G ER+ N H + L+++W+ R + L+ +
Sbjct: 2648 DLQEHG-ERLVAENRESSVRNDHVEKALRNLEDLNKHLHDSWKG-------RFRGLKEAH 2699
Query: 5386 LLHKFYHDCRDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIE 5562
L F + + K + DDLG ++V AL +KH+ + K + + ++ ++E
Sbjct: 2700 QLQLFKEQADQIVEWLTNKEAFLNNDDLGESFTAVEALIKKHEAFEKLLHS--NRIGELE 2757
Query: 5563 RDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLL 5742
R A E+ + +A I R VV L + R +L ++ L +F+ + ++
Sbjct: 2758 RFAEEIL-AESPFEADVIKQRLYAVVSRKDKLLASAETRKQKLQESLQLQQFLRSLYEVE 2816
Query: 5743 LWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYA 5922
W ++ K ++ E ++ S ++ + H + AE+ A A I G L+N +HYA
Sbjct: 2817 KWTNQ-KMQIALDENYREPSNLQSKIQKHAAFDAELLANSGRVTAVIEEGESLINAEHYA 2875
Query: 5923 SSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKE 6102
SS ++++L + E ++ ++ E L E F R +W+ E L S++
Sbjct: 2876 SSLVQEQLDIVENEWQKLREASREKKERLAEAYEALLFQRSLEDFNNWMDEVEAQLSSED 2935
Query: 6103 YGRNLEETIKLIKKHEAFE 6159
YGR+L L+KKH+ E
Sbjct: 2936 YGRDLASVHNLLKKHDMLE 2954
Score = 291 bits (744), Expect = 2e-76
Identities = 292/1507 (19%), Positives = 628/1507 (41%), Gaps = 16/1507 (1%)
Frame = +1
Query: 1792 TIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTG 1971
++D+R + Y +L DLA R+ LED+ L +F+ + + E IK++E++L + D
Sbjct: 969 SVDKRQKHINGTYDQLQDLAERRRALLEDSICLFRFYRECDDFEKWIKDKEKMLRTDDPK 1028
Query: 1972 RDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYIN 2151
+ T + + N+L K ++ +D ++ + D + R +I
Sbjct: 1029 GSVETARR---QFETFVNDLSASSKRVEAIDSDVEDFVRQGHSQLDKVKARQRQIHQMWE 1085
Query: 2152 KLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHD 2331
L L +++ L G F+ ++ ++ + + + + +VG D TVQ L ++H+
Sbjct: 1086 HLNYLKGQKEKSLEGASSVELFYRTCEEAIDWMNEKMTQLDTAEVGPDLKTVQALQRRHE 1145
Query: 2332 DVHDELQNFDQHIKVL----HAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQ 2499
++ EL + + + + S P E R++ +QR L QK ++ ++ R+
Sbjct: 1146 NLERELAPVKEKVSRVNLLGNTVKNSYPSE-RDNVSEKQRDIQNLWQK--VQEKAKERRS 1202
Query: 2500 RLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEA 2679
RL +A+ + ++ +WI E LA RD+E E + + L +D+ +
Sbjct: 1203 RLENAVGQQIFNNSTKALLNWIAECNNQLAAEETARDVETAEKLLKKHKDLGEDINAHDD 1262
Query: 2680 KVTNVNDLARQLL--NVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFR 2853
+ + L +Q++ N ++ ++ KL A +L K +L++ L+ F
Sbjct: 1263 EFVQLAKLGQQIIERNPALTEDHEMANKIAKLEAERQRLHGAWLAKEKKLQQCIELQIFN 1322
Query: 2854 IDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADD 3033
+ + + LE D L N L V + +R E LGA L + + AD
Sbjct: 1323 READKIDATTKSHEAYLEYDD-LGNSLDDVEAIMKRHIDFENSLGAQDKILKNFSEGADR 1381
Query: 3034 IERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTAT 3213
+ R A I + ++ + + + ++ L + D Q+F D+D WL A
Sbjct: 1382 LIRNNHYNATYIDDRRGQVLARRERVKELAQKRRNALQASKDFQKFSSDVDDLNRWL-AD 1440
Query: 3214 QRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLR 3393
+ ++AS+E + L+ + L +H A E+ + + G+ + +T+ + +
Sbjct: 1441 KTKIASDESYKDLSNLPRKLQKHKAFERELRANEGQLRMVNKEGESLI--KTNNRAGEVS 1498
Query: 3394 QRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSL 3573
+ LA + + W++L ++ L Q + R + ++ + ++ L + L
Sbjct: 1499 ETLAAINQNWKDLVATSLDKGRRLEQAALQREHNRYIEDSKSKFEELDHALQSKQVGNDL 1558
Query: 3574 EQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANR 3753
+ + +HQ + ++K+ + G+++ +GH+ A+ I + + + + +
Sbjct: 1559 RSCKELMNKHQVLENDIALWEQKVAELVTTGEEMAHEGHFDANNIQNETKKLQAQFAGLK 1618
Query: 3754 EKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQ 3930
A++ L ++L +F+ + D +WI E + A+ E ++ S +H+ +
Sbjct: 1619 TPARQRRDALDESLRFHKFVFELDTELQWINEHLPAAKSEVIGQNLHQAQSLSKKHKKLE 1678
Query: 3931 SELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDAN 4110
+E+ ++ +++ +A NL + + L W +L++ + E+ +KL +
Sbjct: 1679 AEIEGHQPMINKTLTSAENLINQNHPERAKVKELCNSLEKAWADLQEQSAERSRKLELSL 1738
Query: 4111 RQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHI-DXX 4287
+ Q Y+ +++ W + N + D D + + K +IE E+ + + +
Sbjct: 1739 KAQQYLSDAGEIETWLGERNNVLRSSDYGRDRDSATKLLTKHKVIELELDTYSGIVSEMG 1798
Query: 4288 XXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEK 4467
HPD + I A + +++ L+ LQ R+ L ++ + + +
Sbjct: 1799 HTASAMIAAKHPDS-KVIAAKQQLIEKMLKSLQRLAGQRQLRLMESLYRHEYFVESAELE 1857
Query: 4468 LWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHAN 4647
WI E+ +++ G LQ L + I+ NQ N ++LI
Sbjct: 1858 QWIKEQEQAVNSEDYGHDYEHLLILQNKFDDLKHRIEVGAERFNQCENFAKKLIGGDSPY 1917
Query: 4648 GPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDE 4827
EK+ + L +AWQ L E + R+ L + + H+F D EA + + + + E
Sbjct: 1918 VSEIEKRQELLSNAWQHLLEQLDAREKKLHAAGEIHRFHRDAAEA-LFRIQDKNAALSSE 1976
Query: 4828 RGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSP--LTEQIQVRQAQIE 5001
GKD S +KHE ++++ ++ L + + ++ K P + I Q +
Sbjct: 1977 LGKDLNSALALARKHEAFENELVPLEAQLQVLVDDSLR-LQTKYPGDNAKAIAAEQENVI 2035
Query: 5002 KLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQ 5181
+ + L++ ++ DL+ W + ++E+ D L+
Sbjct: 2036 QYWNVLKEKSALRNDQLHASCDLQHFLTQVRDLMSWATNLRAALQAEEHVSDAAGATALK 2095
Query: 5182 ERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTR 5361
+ + E + N+ D+++ GH A + +L + L + +
Sbjct: 2096 IQHDAIYGEIE-AREQTFRELNELSDSMVQTGHYAATEVEEKCSALLDERAKLHSAYNKK 2154
Query: 5362 AQILEASRLLHKFYHDCR--DCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAA 5535
+LE L F D + D +S E T D G+ V ++H+ + K I
Sbjct: 2155 KILLEQKIDLFCFMRDAKVIDNISSGQEAT-LSSSDFGQTVEVVQDQVKRHEAFEKLIQT 2213
Query: 5536 IGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFK 5715
E+VA ++ +L + D +I R E+V+ + ++ LC R +L + +
Sbjct: 2214 QDEKVAILQEHGRKLVEQNHYDSE-NIRRRLREIVERRQKVKDLCALRRQKLANALLYAQ 2272
Query: 5716 FMNMVRDLLLWMDEVKREM----NSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACI 5883
F+ + W++E ++++ +S ++ + Q+ AE++A E
Sbjct: 2273 FIRDCAEAGAWINEKQKKLEADAHSYAGASNMEDKVKKLKKLQAFDAEVNANEGRIREVR 2332
Query: 5884 SLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAES 6063
G L+ +KH + EI+ +L+KL ++ R L+ ++ +F E+
Sbjct: 2333 DKGEKLIAKKHECAGEIQDELVKLMQSWNVLLNELASRSRGLKEAQDILEFNTQLDKLEA 2392
Query: 6064 WLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHRE 6243
W+ +E + + E GR+LE L +K + + ++R + +L + + +
Sbjct: 2393 WIRDKEMMIHAGETGRDLEHCNALRRKLDDVDSDMRVDDQRIKNINQLADKLVSQDKVEG 2452
Query: 6244 EETAKRR 6264
+ +RR
Sbjct: 2453 KNVQQRR 2459
Score = 65.9 bits (159), Expect = 1e-08
Identities = 44/147 (29%), Positives = 65/147 (43%)
Frame = +1
Query: 6220 LKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDDGAKQGEAFEGTLIRKHTYESL 6399
LK + T +RR + + P +E+ D +G L RKH +S
Sbjct: 3724 LKPVKRAPSFTTRRRAQSFRKNQRAGGPGSES-----DASLLPPVEIQGMLERKHELQSG 3778
Query: 6400 DRKAANRSWEKLYAVLRQNELSFYKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVL 6579
+KA RSW+ Y VL L F+KD + P+ + A +Y KKKNV
Sbjct: 3779 GKKAPVRSWKPFYTVLCGQLLCFFKDGEDFAMQKAATAPVNILNAKCERAENYTKKKNVF 3838
Query: 6580 SLRLPIGAEYLFQCGSEEDMQRWLTEL 6660
L L G+E+LF S+E + W+ +L
Sbjct: 3839 RLVLLDGSEFLFMTNSKESLSEWVNKL 3865
Score = 49.3 bits (116), Expect = 0.001
Identities = 54/214 (25%), Positives = 93/214 (43%), Gaps = 21/214 (9%)
Frame = +1
Query: 5683 SRLMDTSDL-FKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSL---- 5838
++LMD +F +++ +LL W+ E+ + P V G++ L ++++
Sbjct: 284 NKLMDADKKKMQFEHLITNLLSWIRAKTVELEKRNFPNSVEGIQGELLAFKEYRTVEKPP 343
Query: 5839 ----KAEIDAREENFNACISLGRDLLNRKHYAS------SEIEKKLIKLTTERAEMMRRW 5988
++EI+A + N + LN+ HY ++IEK +L E AE R
Sbjct: 344 KYKERSEIEALYFHVNTLLKS----LNQPHYTPQDGKMINDIEKAWQRL--ENAEHNREV 397
Query: 5989 EDRWEYL-QLILEV--YQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFE 6159
R E L Q LE ++F + + + E +L L YG L + +KKHEA
Sbjct: 398 ALRDELLRQEKLEQLNFKFEKKSVLREGYLNEMIQVLTDPRYGPALRQVDATVKKHEAIS 457
Query: 6160 KSAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
A+ +RF L + +E H ++ KR
Sbjct: 458 ADILARADRFNDLTDMCNELHQENYHGKDRVKKR 491
>gi|7655|emb|CAA37939.1| betaH spectrin [Drosophila melanogaster]
Length = 1645
Score = 730 bits (1885), Expect = 0.0
Identities = 477/1640 (29%), Positives = 807/1640 (49%), Gaps = 65/1640 (3%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGER 255
FE RIK L +ER +QKKTFTKW+NS L++ +V+DL+ D+ DG LL+LL ++S E+
Sbjct: 23 FENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEK 82
Query: 256 LPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQI 435
L KP G+MR+H +ENV K L FL + V LE++G+ DIVDGN RL LGLIWTIILRFQI
Sbjct: 83 LGKPNSGRMRVHKIENVNKSLAFLHTK-VRLESIGAEDIVDGNPRLILGLIWTIILRFQI 141
Query: 436 QDITF---EDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHR 606
Q+I E+ ++ E RSAK+ALLLWCQ KT GYP VN+ +F+ SWR GL FNALIH HR
Sbjct: 142 QEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHR 201
Query: 607 PDLVDYDNL--QKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
PDL +Y + K++ L NL AFDTA N+LG+ LDAED++ +PDEKSI+TYV +YY
Sbjct: 202 PDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYY 261
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
H F ++K + GKRI ++ +LM+ D+ +YE L+++LL WI K L +R N+L
Sbjct: 262 HTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSL 321
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
EG+QR+L F +YRT EKPPK+ E+ E+E L FT+ + ++A NQ P+ P++G+L+ DI +
Sbjct: 322 EGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEK 381
Query: 1141 AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDL 1320
AWQ LE AEH RE+ L++EL+RQEKLEQL +F +K+ +RE +L E +++S + L
Sbjct: 382 AWQILEYAEHHREVALRDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRY---L 438
Query: 1321 SSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXX 1500
V+A KKHEAI DI A ER NYH + ++ R++ V
Sbjct: 439 RQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLL 498
Query: 1501 XXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLE 1680
+R+ L + + ++ + SED+G HL+ VE+LLQ H+L E
Sbjct: 499 ELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQE 558
Query: 1681 SDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAER 1860
+N GE + QA +++ + D + + +R L++ Y ELL +A R
Sbjct: 559 LQVNTYGETLKRFNRQALPYKSSEHKDAA--------LLAQRLADLEEAYSELLRRSAAR 610
Query: 1861 KRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDL 2040
+ RLE+ + F D E + +++++ + T +D+ V L KHK E+ ++
Sbjct: 611 RARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSR 670
Query: 2041 EKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFF 2220
+ ++ +GK L E P S I R+ + ++ L+ L R+ +L E YQF+
Sbjct: 671 KPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFY 730
Query: 2221 TDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESL 2400
TDA++ + +L + + +++S D G DE + Q LL++H D+ EL + I L+ +A+ L
Sbjct: 731 TDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKL 790
Query: 2401 PQEA----------REHPDIRQR---LDTTLKQK--------AELENLSQLRKQRLIDAL 2517
+ E P++ Q +T L K +LE+ + L
Sbjct: 791 IKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVK 850
Query: 2518 SLY--------------KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLE 2655
SL+ L + + W K + VP + EVE +
Sbjct: 851 SLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPK 910
Query: 2656 QDMKNQEAKVTNVNDLARQLLNVE----------------------HPNSDDILHRQNKL 2769
+ KV L RQ++ V+ + N+D + RQ ++
Sbjct: 911 AEKVKSLQKVKK-TILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRI 969
Query: 2770 NARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMK 2949
N + +L++M ++ LE + L F +C + W+++K R+++ + GV
Sbjct: 970 NQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEG-----EGVDN 1024
Query: 2950 LQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVRE 3129
+R+ DL A +++ + D R+ + I ++IHQ+W LN +
Sbjct: 1025 AKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQ 1084
Query: 3130 HEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDG 3309
E L+ A ++ F R D + W++ Q+ + L + L +H + E+
Sbjct: 1085 REKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAP 1144
Query: 3310 YAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQM 3489
+ ++ +G+ V ++ + + R +Q+ W+++Q+ + ++ + + Q+
Sbjct: 1145 VEDKVNRVTYLGNSV-KNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQV 1203
Query: 3490 FLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGD 3669
F AK + ++ L D+ + +E A N LK+H D + A+D + V G
Sbjct: 1204 FNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGK 1263
Query: 3670 QLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIE- 3846
QL A+ + R E+ +R A E K L + LQ F + D++ +
Sbjct: 1264 QLSDGKPNMAETVAVIERLKAEQDAIHRGWA-EKQKWLLQCVDLQMFNREADKIDATTKS 1322
Query: 3847 EKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINL-GDDKPEYHGTI 4023
+ + + + RH F+ L A + L A L +D +
Sbjct: 1323 HEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKYIG 1382
Query: 4024 DPQIEELATQWDELEKTTEEKGQKLFDANRQ-QLYVQSIADMKEWATQLENEMTREDQPG 4200
D + + L + ++ E K +L A++ + D+K W Q + + ++
Sbjct: 1383 DRRNQVLGKRKAVKDRAFERK--RLLQASKDFHKFAAEADDLKVW-LQDKTRIAGDENYR 1439
Query: 4201 DLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQR 4380
DL+ + +QK E E+ + + + +++ + ++ +
Sbjct: 1440 DLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQA-GNRVPEVESRVADLNKRWKD 1498
Query: 4381 LQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQL 4560
L +D+ + LE+ + + R ++D K + E ++ ++G L C L Q+
Sbjct: 1499 LLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLRSCKDLINKQQI 1558
Query: 4561 LSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGE 4740
L +EI + + ++ + G ++ GH N E +EL+ +++L++ + R+ L E
Sbjct: 1559 LESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKLEE 1618
Query: 4741 SEKAHQFLYDCGEAEAWMSE 4800
S H+F+++ W++E
Sbjct: 1619 SLNYHKFVFELDSEFQWINE 1638
Score = 306 bits (783), Expect = 6e-81
Identities = 265/1169 (22%), Positives = 500/1169 (42%), Gaps = 66/1169 (5%)
Frame = +1
Query: 1195 ELIRQEKLE--QLAARFNRKAEMRETW--LTENQRLVSQDNFGNDLSSVEAATKKHEAIE 1362
EL+ ++L Q++ N E+ T + E Q+ + ++ G L VE + H E
Sbjct: 499 ELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQE 558
Query: 1363 TDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSM 1542
+ Y E + D A + +R ++ ARR RLE +
Sbjct: 559 LQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEAR 618
Query: 1543 AIQKIFHXXXXXXXXXXXIKSRLLSEDLGAH-LMDVEDLLQKHALLESDINIIGERVNNS 1719
F K R+ + A L V L QKH LE +I +
Sbjct: 619 NFHH-FMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQM 677
Query: 1720 IAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQF 1899
+R P S I R D L + ++ L L R+R+LED QF
Sbjct: 678 STAGKRLIGEQHPRSS--------EIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQF 729
Query: 1900 WWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLR-------DLEKYLDR 2058
+ D E E + E+ +++S D G D + LL +H++ + L +L + D+
Sbjct: 730 YTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADK 789
Query: 2059 LDVSG-------------KELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
L +G E++ E + P+ +++ KL+ + + L
Sbjct: 790 LIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHV 849
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSED---VGKDEGT----------------VQLLLK 2322
+ F +D+ L+ +++D V KD G V ++
Sbjct: 850 KSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVP 909
Query: 2323 KHDDVHDELQNFDQ-----------HIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKA- 2466
K + V LQ + IK + + L Q I + D+ K++
Sbjct: 910 KAEKVKS-LQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQR 968
Query: 2467 ------ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEI 2628
EL+ ++Q R L D++ L+ Y + D E W+ EK +++ + + E V+
Sbjct: 969 INQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKS----DEGEGVDN 1024
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
K +F+ D+ +V ++ H D I+ RQ +++ W +L + Q
Sbjct: 1025 AKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQ 1084
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
+ LE A +E F C E W+ +K L D+ +T DL V LQRR +ER+L
Sbjct: 1085 REKSLEGASSVELFNRTCDEAKVWMSEKMLQL-DTAVITPDLRTVQALQRRHQNLERELA 1143
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
++ K++ + + ++ P E + + + +W + ++ + +++ Q
Sbjct: 1144 PVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQV 1203
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
F AW+ + + Q+ ++E + + A LL +H + ++I + ++ ++ +G
Sbjct: 1204 FNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGK 1263
Query: 3349 RVTQDQTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
+++ + + + + + +RL Q+ + R W +Q L Q ++LQMF R+A + +
Sbjct: 1264 QLSDGKPNMAETVAVIERLKAEQDA---IHRGWAEKQKWLLQCVDLQMFNREADKIDATT 1320
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
E +L +++ SL++ E LKRH DF ++ A D+ ++ D+L + HY +
Sbjct: 1321 KSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKY 1380
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
I + + +R A +++A E + L+ + +F ++ D+L+ W+++K A DE YRD
Sbjct: 1381 IGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRD 1440
Query: 3886 AKTITSKFVRHQAFQSELAANKERLDQLK---HAAINLGDDKPEYHGTIDPQIEELATQW 4056
+ K +HQAF+ EL AN+ +L + A + G+ PE ++ ++ +L +W
Sbjct: 1441 LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE----VESRVADLNKRW 1496
Query: 4057 DELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQ 4236
+L +E+KG+KL A Q+ + +S+ D K+ +L+ + D DL + + KQ
Sbjct: 1497 KDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLRSCKDLINKQ 1556
Query: 4237 HLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKAL 4416
++E+E+ Q + +NI+A +Q++ + L+ P RR L
Sbjct: 1557 QILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKL 1616
Query: 4417 ERKKAAFQFGRDVDDEKLWISERLVLAKA 4503
E +F ++D E WI+E L AK+
Sbjct: 1617 EESLNYHKFVFELDSEFQWINEHLPAAKS 1645
Score = 185 bits (469), Expect = 2e-44
Identities = 229/1134 (20%), Positives = 455/1134 (39%), Gaps = 80/1134 (7%)
Frame = +1
Query: 3022 EADDIERERPQEAQAIREDIKRIHQVWDILN-----KKVREHEAKLDEAGDLQRFLRDLD 3186
+A+DI+ RP E + H + N K++ +L +A + L
Sbjct: 239 DAEDIDSARPDEKSILTYVASYYHTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLT 298
Query: 3187 -HFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIR--EEIDGYAED------YKKMRA 3339
+ +W+ ++ + P SL ++ L R E+ Y E Y +
Sbjct: 299 TNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINT 358
Query: 3340 MGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAK-QAE 3516
+ + Q +PQ Q + +++ W+ L+ +R+ L L Q L + E
Sbjct: 359 LLKALNQPPYNPQD---GQLVNDIEKAWQILEYAEHHREVALRDELLRQEKLEQLNYKFE 415
Query: 3517 VMLSQQENYLAKDDI-----PQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQ 3681
+E YL K+ I P+ L Q + LK+H+ + A E+ + ++L +
Sbjct: 416 KKSVLREGYL-KEMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEELDR 474
Query: 3682 DGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIR 3861
+ ++ +++ ++ + + + E + L +L L + E + E +
Sbjct: 475 ENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQ 534
Query: 3862 AQDETYRDAKTITSKFVRHQAFQSELAANK--ERLDQLKHAAINLGDDKPEYHGTIDPQI 4035
E + ++ + Q EL N E L + A+ + + + ++
Sbjct: 535 FASEDVGPHLLGVEELLQAHSLQ-ELQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRL 593
Query: 4036 EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTV 4215
+L + EL + + + +L +A +++ + + W + DL V
Sbjct: 594 ADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAV 653
Query: 4216 NVAMQKQHLIETEM-IKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAP 4392
QK +E E+ +K + HP E I++ ++ E Q L+A
Sbjct: 654 LSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSE-IQSRIDSLAEHWQALEAL 712
Query: 4393 LDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNE 4572
++ RR+ LE A+QF D ++ + W++E++ L +++ G P L + + L E
Sbjct: 713 VELRRRQLEDAAEAYQFYTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGE 772
Query: 4573 IDNHEPWINQICNNGQELIDEG------HANGPAF-----EKKIQELR--------SAWQ 4695
++ + I + +LI G A P E+ + E R W
Sbjct: 773 LNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWV 832
Query: 4696 ELKEAVKDRKGDLGESEKA------HQFLYDCGEAEAWMSE--QELYMMQDERGKDEFST 4851
E E K + + K+ D GE S+ + + ++ + G + F
Sbjct: 833 EKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVP 892
Query: 4852 KNQIK------------KHERLQSDIDKFADTIRALATKAHKFVEEKS----PLTEQ--- 4974
N ++ K E+++S + K TI K ++ S PL ++
Sbjct: 893 ANYVREVEPRPVACIVPKAEKVKS-LQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTS 951
Query: 4975 ----------IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKE 5124
++ RQ +I + Y LQ+ + +RE DD +W+ +KE
Sbjct: 952 TQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKE 1011
Query: 5125 VVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIAL 5304
+ S E E V + +F++F D + S+RV + DT GH+ I
Sbjct: 1012 RMIKSDEG----EGVDNAKRKFEKFITDL-SAASKRVEEIDGAVDTFRRQGHSQLDKIIA 1066
Query: 5305 WKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDD-LGRDSS 5481
+ +++ W+ L R + LE + + F C + + EK + + D
Sbjct: 1067 RQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLR 1126
Query: 5482 SVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLR 5661
+V AL R+HQN +++A + ++V ++ +++ Y +K ++ +R+ EV W+ ++
Sbjct: 1127 TVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKD-NVNARQQEVQDMWQQVQ 1185
Query: 5662 GLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLK 5841
+R+ F N + LL W+D VK ++N+ E +DV L+ H L
Sbjct: 1186 QRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLG 1245
Query: 5842 AEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLIL 6021
+I A + F I LG+ L + K + + + +L E+ + R W ++ ++L +
Sbjct: 1246 DDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAV-IERLKAEQDAIHRGWAEKQKWLLQCV 1304
Query: 6022 EVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEE 6183
++ F R+A ++ + E +L G +L+E ++K+H FEKS AQ++
Sbjct: 1305 DLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDK 1358
Score = 168 bits (426), Expect = 1e-39
Identities = 225/1204 (18%), Positives = 447/1204 (36%), Gaps = 75/1204 (6%)
Frame = +1
Query: 2812 RNELERAHRLETFRIDCQETVT----WIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMER 2979
R+EL R +LE ++ ++++ +VL D L + +K +S
Sbjct: 398 RDELLRQEKLEQLNYKFEKKSVLREGYLKEMIQVLSDPRYL-RQVDATLKKHEAISA--- 453
Query: 2980 DLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGD 3159
D+ A + + L A++++RE + +R + + W L + + L + +
Sbjct: 454 DILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSN 513
Query: 3160 LQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRA 3339
L LR++ + Q+Q ASE+ L E+LL H+ +++ Y E K+
Sbjct: 514 LMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNR 573
Query: 3340 MGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEV 3519
+ + L QRLA L+E + EL R R+ L + N F+ D E
Sbjct: 574 QALPYKSSEHKDAAL-LAQRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEES 632
Query: 3520 MLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAA 3699
L ++ + L + ++H+ + + K + G +L + H +
Sbjct: 633 WLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRS 692
Query: 3700 DKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY 3879
+I + ++ E A + ++L+DA QF +D +E W+ EKM Y
Sbjct: 693 SEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQFYTDANEAESWLNEKMALVNSRDY 752
Query: 3880 -RDAKTITSKFVRHQAFQSELAANK-------ERLDQLKHAAI---NLGDDKPEYHGTID 4026
D + + RH+ Q EL A ++ D+L A I L +PE
Sbjct: 753 GNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPEL----- 807
Query: 4027 PQIEE--------------LATQWDEL---EKTTEEK------------GQKLFDANRQQ 4119
P++E+ +W E +K TE K GQ + +
Sbjct: 808 PEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEV 867
Query: 4120 LYVQSIADMKEWATQLENEM--------TREDQPGDLTTVNVAMQK-------------Q 4236
+ ++S + W + +N + RE +P + + +K +
Sbjct: 868 MLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVR 927
Query: 4237 HLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKAL 4416
++ + IK + ++++ + + + LQ R L
Sbjct: 928 QVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALL 987
Query: 4417 ERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWI 4596
E F F R+ DD + W+ E+ + K+ GE + + R + ++ +
Sbjct: 988 EDSIHLFGFYRECDDFEKWMKEKERMIKSDE-GEGVDNAKR---KFEKFITDLSAASKRV 1043
Query: 4597 NQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCG 4776
+I +GH+ + +++ WQ L A R+ L + F C
Sbjct: 1044 EEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCD 1103
Query: 4777 EAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEK 4956
EA+ WMSE+ L + D + + ++H+ L+ ++ D + + +
Sbjct: 1104 EAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAY 1163
Query: 4957 SPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAG 5136
+ + RQ +++ ++ +Q + LL WI +
Sbjct: 1164 PAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLN 1223
Query: 5137 SQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWK-- 5310
+ E+ +D E L ++ D +E V G G + A T+A+ +
Sbjct: 1224 ADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGKQLSDGKPNM-AETVAVIERL 1282
Query: 5311 ----DSLNEAWEN----LLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDL 5466
D+++ W LL+ +D + EA ++ D ++ E ++L
Sbjct: 1283 KAEQDAIHRGWAEKQKWLLQCVDLQMFNREADKI---------DATTKSHE-AFLEYNNL 1332
Query: 5467 GRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKA 5646
G V A+ ++H ++ K + A + + +A +L D IG R ++V+
Sbjct: 1333 GASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKY-IGDRRNQVLGK 1391
Query: 5647 WRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNN 5826
+ ++ R L + D KF DL +W+ + K + E +D+S + +
Sbjct: 1392 RKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQD-KTRIAGDENYRDLSNLPRKLQK 1450
Query: 5827 HQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEY 6006
HQ+ + E+ A E G+ L+ + E+E ++ L +++ ED+
Sbjct: 1451 HQAFERELRANEGQLRNVTKDGQALVQAGNRVP-EVESRVADLNKRWKDLLTLSEDKGRK 1509
Query: 6007 LQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEER 6186
L+ + R A+ + + L S + G +L LI K + E +++
Sbjct: 1510 LEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLRSCKDLINKQQILESEITIWDQK 1569
Query: 6187 FLAL 6198
L
Sbjct: 1570 VAEL 1573
Score = 144 bits (362), Expect = 4e-32
Identities = 136/689 (19%), Positives = 287/689 (40%), Gaps = 5/689 (0%)
Frame = +1
Query: 4018 TIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP 4197
+++ + + + +DEL++ +++ L D+ + + D ++W + E + ++
Sbjct: 961 SVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEGE 1020
Query: 4198 GDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQ 4377
G V+ A +K T++ ++ ++ +L+ I A + + + Q
Sbjct: 1021 G----VDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQ 1076
Query: 4378 RLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQ 4557
RL R K+LE + F R D+ K+W+SE+++ + L LQ+ Q
Sbjct: 1077 RLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQ 1136
Query: 4558 LLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLG 4737
L E+ E +N++ G + + A + QE++ WQ++++ D + +
Sbjct: 1137 NLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRI- 1195
Query: 4738 ESEKAHQFLYDCGEAE-AWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTI 4914
ESE Q + + AW+ + + DE +D + N +KKH L DI
Sbjct: 1196 ESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEF 1255
Query: 4915 RALATKAHKFVEEKSPLTEQIQVRQAQIEKLYA---GLQDXXXXXXXXXXXXXXXYALHR 5085
+ + + K + E + V IE+L A + +R
Sbjct: 1256 VEVIQLGKQLSDGKPNMAETVAV----IERLKAEQDAIHRGWAEKQKWLLQCVDLQMFNR 1311
Query: 5086 EIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANA-NDGCDT 5262
E D + E G + V+ + +R F + + +++ +D D
Sbjct: 1312 EADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSL--MAQDKILKGFSDNADK 1369
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
LI + H D+ I ++ + + + + R ++L+AS+ HKF + D + +K
Sbjct: 1370 LISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDK 1429
Query: 5443 THAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGS 5622
T D+ RD S++ +KHQ + +++ A Q+ + +D L AG++ ++ S
Sbjct: 1430 TRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQ--AGNRVPEVES 1487
Query: 5623 RESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVS 5802
R +++ K W+ L L + + +L + + + D +DE+ + S + D+
Sbjct: 1488 RVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLR 1547
Query: 5803 GVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMR 5982
+ L+N Q L++EI ++ +S G D+ + H+ + IE +L ++
Sbjct: 1548 SCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRD 1607
Query: 5983 RWEDRWEYLQLILEVYQFARDAAVAESWL 6069
+ R L+ L ++F + W+
Sbjct: 1608 PTQRRRAKLEESLNYHKFVFELDSEFQWI 1636
Score = 85.9 bits (211), Expect = 1e-14
Identities = 68/309 (22%), Positives = 132/309 (42%), Gaps = 1/309 (0%)
Frame = +1
Query: 5284 DAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDD 5463
+A ++ + +N+ ++ L E+ R +LE S L FY +C D + EK + D
Sbjct: 958 NADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSD 1017
Query: 5464 LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALD-IGSRESEVV 5640
G V RK + ++ D++A ++V +I+ R G LD I +R+ ++
Sbjct: 1018 EG---EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFR--RQGHSQLDKIIARQRQIH 1072
Query: 5641 KAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLM 5820
+ W+ L R L S + F + +WM E ++++ D+ V+ L
Sbjct: 1073 QIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQ 1132
Query: 5821 NNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRW 6000
HQ+L+ E+ E+ N LG + N + + ++ ++ +R D
Sbjct: 1133 RRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLR 1192
Query: 6001 EYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQE 6180
++ + F A V +W+ + + L + E R++E L+KKH A +
Sbjct: 1193 NRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHD 1252
Query: 6181 ERFLALEKL 6207
F+ + +L
Sbjct: 1253 TEFVEVIQL 1261
Score = 39.7 bits (91), Expect = 1.0
Identities = 48/213 (22%), Positives = 92/213 (42%), Gaps = 21/213 (9%)
Frame = +1
Query: 5686 RLMDTS-DLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSL----- 5838
+LMD ++ + +LL W+ + E+ ++ P + G++ L ++++
Sbjct: 283 QLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPK 342
Query: 5839 ---KAEIDAREENFNACISLGRDLLNRKHYAS------SEIEK--KLIKLTTERAEMMRR 5985
++EI+A N + LN+ Y ++IEK ++++ E+ R
Sbjct: 343 YKERSEIEALYFTINTLLKA----LNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALR 398
Query: 5986 WED-RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
E R E L+ + Y+F + + + E +L L Y R ++ T+K KHEA
Sbjct: 399 DELLRQEKLEQLN--YKFEKKSVLREGYLKEMIQVLSDPRYLRQVDATLK---KHEAISA 453
Query: 6163 SAFAQEERFLALEKLTTFELKETQHREEETAKR 6261
A+ ERF L + +E H +E +R
Sbjct: 454 DILARVERFNDLTAMAEELDRENYHGKERVRRR 486
>gi|103502|pir||A37792 spectrin beta-H chain - fruit fly (Drosophila
melanogaster) (fragment)
Length = 1645
Score = 718 bits (1853), Expect = 0.0
Identities = 475/1642 (28%), Positives = 805/1642 (48%), Gaps = 67/1642 (4%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGER 255
FE RIK L +ER +QKKTFTKW+NS L++ +V+DL+ D+ DG LL+LL ++S E+
Sbjct: 23 FENERIKTLQEERLHIQKKTFTKWMNSFLIKAKMEVEDLFTDLADGIKLLKLLEIISSEK 82
Query: 256 LPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQI 435
L KP G+MR+H +ENV K L FL + V LE++G+ DIVDGN RL LGLIWTIILRFQI
Sbjct: 83 LGKPNSGRMRVHKIENVNKSLAFLHTK-VRLESIGAEDIVDGNPRLILGLIWTIILRFQI 141
Query: 436 QDITF---EDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHR 606
Q+I E+ ++ E RSAK+ALLLWCQ KT GYP VN+ +F+ SWR GL FNALIH HR
Sbjct: 142 QEIEIDVDEENESSEKRSAKDALLLWCQRKTHGYPGVNITDFTNSWRSGLGFNALIHSHR 201
Query: 607 PDLVDYDNL--QKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
PDL +Y + K++ L NL AFDTA N+LG+ LDAED++ +PDEKSI+TYV +YY
Sbjct: 202 PDLFEYSTIVNSKNSNLDNLNHAFDTAANELGIPSLLDAEDIDSARPDEKSILTYVASYY 261
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
H F ++K + GKRI ++ +LM+ D+ +YE L+++LL WI K L +R N+L
Sbjct: 262 HTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSL 321
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
EG+QR+L F +YRT EKPPK+ E+ E+E L FT+ + ++A NQ P+ P++G+L+ DI +
Sbjct: 322 EGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKALNQPPYNPQDGQLVNDIEK 381
Query: 1141 AWQSLEKAEHERELVLKEE--LIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGN 1314
AWQ LE AEH RE+ L++E L+RQEKLE +F +K+ +RE +L E +++S +
Sbjct: 382 AWQILEYAEHHREVALRDEQLLLRQEKLENY--KFEKKSVLREGYLKEMIQVLSDPRY-- 437
Query: 1315 DLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXX 1494
L V+A KKHEAI DI A ER NYH + ++ R++ V
Sbjct: 438 -LRQVDATLKKHEAISADILARVERFNDLTAMAEELDRENYHGKERVRRREQEVMAKWRQ 496
Query: 1495 XXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHAL 1674
+R+ L + + ++ + SED+G HL+ VE+LLQ H+L
Sbjct: 497 LLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSL 556
Query: 1675 LESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAA 1854
E +N GE + QA +++ + D + + +R L++ Y ELL +A
Sbjct: 557 QELQVNTYGETLKRFNRQALPYKSSEHKDAA--------LLAQRLADLEEAYSELLRRSA 608
Query: 1855 ERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLR 2034
R+ RLE+ + F D E + +++++ + T +D+ V L KHK E+ ++
Sbjct: 609 ARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIK 668
Query: 2035 DLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQ 2214
+ ++ +GK L E P S I R+ + ++ L+ L R+ +L E YQ
Sbjct: 669 SRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQ 728
Query: 2215 FFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAE 2394
F+TDA++ + +L + + +++S D G DE + Q LL++H D+ EL + I L+ +A+
Sbjct: 729 FYTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQAD 788
Query: 2395 SLPQEA----------REHPDIRQR---LDTTLKQK--------AELENLSQLRKQRLID 2511
L + E P++ Q +T L K +LE+ + L
Sbjct: 789 KLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPH 848
Query: 2512 ALSLY--------------KLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDT 2649
SL+ L + + W K + VP + EVE
Sbjct: 849 VKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIV 908
Query: 2650 LEQDMKNQEAKVTNVNDLARQLLNVE----------------------HPNSDDILHRQN 2763
+ + KV L RQ++ V+ + N+D + RQ
Sbjct: 909 PKAEKVKSLQKVKK-TILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQ 967
Query: 2764 KLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGV 2943
++N + +L++M ++ LE + L F +C + W+++K R+++ + GV
Sbjct: 968 RINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEG-----EGV 1022
Query: 2944 MKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKV 3123
+R+ DL A +++ + D R+ + I ++IHQ+W LN
Sbjct: 1023 DNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAK 1082
Query: 3124 REHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEI 3303
+ E L+ A ++ F R D + W++ Q+ + L + L +H + E+
Sbjct: 1083 AQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQNLEREL 1142
Query: 3304 DGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNL 3483
+ ++ +G+ V ++ + + R +Q+ W+++Q+ + ++ + +
Sbjct: 1143 APVEDKVNRVTYLGNSV-KNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQ 1201
Query: 3484 QMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMF 3663
Q+F AK + ++ L D+ + +E A N LK+H D + A+D + V
Sbjct: 1202 QVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQL 1261
Query: 3664 GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI 3843
G QL A+ + R E+ +R A E K L + LQ F + D++
Sbjct: 1262 GKQLSDGKPNMAETVAVIERLKAEQDAIHRGWA-EKQKWLLQCVDLQMFNREADKIDATT 1320
Query: 3844 E-EKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINL-GDDKPEYHG 4017
+ + + + + RH F+ L A + L A L +D +
Sbjct: 1321 KSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKY 1380
Query: 4018 TIDPQIEELATQWDELEKTTEEKGQKLFDANRQ-QLYVQSIADMKEWATQLENEMTREDQ 4194
D + + L + ++ E K +L A++ + D+K W Q + + ++
Sbjct: 1381 IGDRRNQVLGKRKAVKDRAFERK--RLLQASKDFHKFAAEADDLKVW-LQDKTRIAGDEN 1437
Query: 4195 PGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQL 4374
DL+ + +QK E E+ + + + +++ + ++
Sbjct: 1438 YRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQA-GNRVPEVESRVADLNKRW 1496
Query: 4375 QRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNL 4554
+ L +D+ + LE+ + + R ++D K + E ++ ++G L C L
Sbjct: 1497 KDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLRSCKDLINKQ 1556
Query: 4555 QLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDL 4734
Q+L +EI + + ++ + G ++ GH N E +EL+ +++L++ + R+ L
Sbjct: 1557 QILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKL 1616
Query: 4735 GESEKAHQFLYDCGEAEAWMSE 4800
ES H+F+++ W++E
Sbjct: 1617 EESLNYHKFVFELDSEFQWINE 1638
Score = 306 bits (783), Expect = 6e-81
Identities = 265/1169 (22%), Positives = 500/1169 (42%), Gaps = 66/1169 (5%)
Frame = +1
Query: 1195 ELIRQEKLE--QLAARFNRKAEMRETW--LTENQRLVSQDNFGNDLSSVEAATKKHEAIE 1362
EL+ ++L Q++ N E+ T + E Q+ + ++ G L VE + H E
Sbjct: 499 ELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFASEDVGPHLLGVEELLQAHSLQE 558
Query: 1363 TDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSM 1542
+ Y E + D A + +R ++ ARR RLE +
Sbjct: 559 LQVNTYGETLKRFNRQALPYKSSEHKDAALLAQRLADLEEAYSELLRRSAARRARLEEAR 618
Query: 1543 AIQKIFHXXXXXXXXXXXIKSRLLSEDLGAH-LMDVEDLLQKHALLESDINIIGERVNNS 1719
F K R+ + A L V L QKH LE +I +
Sbjct: 619 NFHH-FMEDYDNEESWLVDKQRICKTGITAKDLRAVLSLQQKHKALEDEIKSRKPKSGQM 677
Query: 1720 IAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQF 1899
+R P S I R D L + ++ L L R+R+LED QF
Sbjct: 678 STAGKRLIGEQHPRSS--------EIQSRIDSLAEHWQALEALVELRRRQLEDAAEAYQF 729
Query: 1900 WWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLR-------DLEKYLDR 2058
+ D E E + E+ +++S D G D + LL +H++ + L +L + D+
Sbjct: 730 YTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGELNAYSGDILNLNQQADK 789
Query: 2059 LDVSG-------------KELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGG 2199
L +G E++ E + P+ +++ KL+ + + L
Sbjct: 790 LIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWEDEWVEKLEHKKVTETKMLPHV 849
Query: 2200 VEYYQFFTDADDVDRYLYDTLRVMSSED---VGKDEGT----------------VQLLLK 2322
+ F +D+ L+ +++D V KD G V ++
Sbjct: 850 KSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGFVPANYVREVEPRPVACIVP 909
Query: 2323 KHDDVHDELQNFDQ-----------HIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKA- 2466
K + V LQ + IK + + L Q I + D+ K++
Sbjct: 910 KAEKVKS-LQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRTSTQSINENADSVEKRQQR 968
Query: 2467 ------ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEI 2628
EL+ ++Q R L D++ L+ Y + D E W+ EK +++ + + E V+
Sbjct: 969 INQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKS----DEGEGVDN 1024
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
K +F+ D+ +V ++ H D I+ RQ +++ W +L + Q
Sbjct: 1025 AKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQRLNNAKAQ 1084
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
+ LE A +E F C E W+ +K L D+ +T DL V LQRR +ER+L
Sbjct: 1085 REKSLEGASSVELFNRTCDEAKVWMSEKMLQL-DTAVITPDLRTVQALQRRHQNLERELA 1143
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
++ K++ + + ++ P E + + + +W + ++ + +++ Q
Sbjct: 1144 PVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRIESEVGQQV 1203
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
F AW+ + + Q+ ++E + + A LL +H + ++I + ++ ++ +G
Sbjct: 1204 FNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEFVEVIQLGK 1263
Query: 3349 RVTQDQTD-PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
+++ + + + + + +RL Q+ + R W +Q L Q ++LQMF R+A + +
Sbjct: 1264 QLSDGKPNMAETVAVIERLKAEQDA---IHRGWAEKQKWLLQCVDLQMFNREADKIDATT 1320
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
E +L +++ SL++ E LKRH DF ++ A D+ ++ D+L + HY +
Sbjct: 1321 KSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDKILKGFSDNADKLISNDHYDSKY 1380
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
I + + +R A +++A E + L+ + +F ++ D+L+ W+++K A DE YRD
Sbjct: 1381 IGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDKTRIAGDENYRD 1440
Query: 3886 AKTITSKFVRHQAFQSELAANKERLDQLK---HAAINLGDDKPEYHGTIDPQIEELATQW 4056
+ K +HQAF+ EL AN+ +L + A + G+ PE ++ ++ +L +W
Sbjct: 1441 LSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQAGNRVPE----VESRVADLNKRW 1496
Query: 4057 DELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQ 4236
+L +E+KG+KL A Q+ + +S+ D K+ +L+ + D DL + + KQ
Sbjct: 1497 KDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLRSCKDLINKQ 1556
Query: 4237 HLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKAL 4416
++E+E+ Q + +NI+A +Q++ + L+ P RR L
Sbjct: 1557 QILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRDPTQRRRAKL 1616
Query: 4417 ERKKAAFQFGRDVDDEKLWISERLVLAKA 4503
E +F ++D E WI+E L AK+
Sbjct: 1617 EESLNYHKFVFELDSEFQWINEHLPAAKS 1645
Score = 186 bits (471), Expect = 9e-45
Identities = 229/1137 (20%), Positives = 456/1137 (39%), Gaps = 83/1137 (7%)
Frame = +1
Query: 3022 EADDIERERPQEAQAIREDIKRIHQVWDILN-----KKVREHEAKLDEAGDLQRFLRDLD 3186
+A+DI+ RP E + H + N K++ +L +A + L
Sbjct: 239 DAEDIDSARPDEKSILTYVASYYHTFARMKNEQKSGKRIANIVGQLMDADRKKMQYEGLT 298
Query: 3187 -HFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIR--EEIDGYAED------YKKMRA 3339
+ +W+ ++ + P SL ++ L R E+ Y E Y +
Sbjct: 299 TNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINT 358
Query: 3340 MGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEV 3519
+ + Q +PQ Q + +++ W+ L+ +R+ L Q+ LR K
Sbjct: 359 LLKALNQPPYNPQD---GQLVNDIEKAWQILEYAEHHREVALRDE---QLLLRQEKLENY 412
Query: 3520 MLSQQ----ENYLAKDDI-----PQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQ 3672
++ E YL K+ I P+ L Q + LK+H+ + A E+ + ++
Sbjct: 413 KFEKKSVLREGYL-KEMIQVLSDPRYLRQVDATLKKHEAISADILARVERFNDLTAMAEE 471
Query: 3673 LCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEK 3852
L ++ ++ +++ ++ + + + E + L +L L + E + E
Sbjct: 472 LDRENYHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVREL 531
Query: 3853 MIRAQDETYRDAKTITSKFVRHQAFQSELAANK--ERLDQLKHAAINLGDDKPEYHGTID 4026
+ E + ++ + Q EL N E L + A+ + + +
Sbjct: 532 QQQFASEDVGPHLLGVEELLQAHSLQ-ELQVNTYGETLKRFNRQALPYKSSEHKDAALLA 590
Query: 4027 PQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDL 4206
++ +L + EL + + + +L +A +++ + + W + DL
Sbjct: 591 QRLADLEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDL 650
Query: 4207 TTVNVAMQKQHLIETEM-IKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRL 4383
V QK +E E+ +K + HP E I++ ++ E Q L
Sbjct: 651 RAVLSLQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSE-IQSRIDSLAEHWQAL 709
Query: 4384 QAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLL 4563
+A ++ RR+ LE A+QF D ++ + W++E++ L +++ G P L + + L
Sbjct: 710 EALVELRRRQLEDAAEAYQFYTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDL 769
Query: 4564 SNEIDNHEPWINQICNNGQELIDEG------HANGPAF-----EKKIQELR--------S 4686
E++ + I + +LI G A P E+ + E R
Sbjct: 770 QGELNAYSGDILNLNQQADKLIKAGICTLELSAAEPELPEVEQEEWVNETRLVPKEVWED 829
Query: 4687 AWQELKEAVKDRKGDLGESEKA------HQFLYDCGEAEAWMSE--QELYMMQDERGKDE 4842
W E E K + + K+ D GE S+ + + ++ + G +
Sbjct: 830 EWVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEG 889
Query: 4843 FSTKNQIK------------KHERLQSDIDKFADTIRALATKAHKFVEEKS----PLTEQ 4974
F N ++ K E+++S + K TI K ++ S PL ++
Sbjct: 890 FVPANYVREVEPRPVACIVPKAEKVKS-LQKVKKTILVRQVVPVKRIKPVSVAPKPLVQR 948
Query: 4975 -------------IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIA 5115
++ RQ +I + Y LQ+ + +RE DD +W+
Sbjct: 949 RTSTQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMK 1008
Query: 5116 DKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPT 5295
+KE + S E E V + +F++F D + S+RV + DT GH+
Sbjct: 1009 EKERMIKSDEG----EGVDNAKRKFEKFITDL-SAASKRVEEIDGAVDTFRRQGHSQLDK 1063
Query: 5296 IALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDD-LGR 5472
I + +++ W+ L R + LE + + F C + + EK + +
Sbjct: 1064 IIARQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITP 1123
Query: 5473 DSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWR 5652
D +V AL R+HQN +++A + ++V ++ +++ Y +K ++ +R+ EV W+
Sbjct: 1124 DLRTVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKD-NVNARQQEVQDMWQ 1182
Query: 5653 HLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQ 5832
++ +R+ F N + LL W+D VK ++N+ E +DV L+ H
Sbjct: 1183 QVQQRGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHN 1242
Query: 5833 SLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQ 6012
L +I A + F I LG+ L + K + + + +L E+ + R W ++ ++L
Sbjct: 1243 DLGDDIRAHDTEFVEVIQLGKQLSDGKPNMAETVAV-IERLKAEQDAIHRGWAEKQKWLL 1301
Query: 6013 LILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEE 6183
+++ F R+A ++ + E +L G +L+E ++K+H FEKS AQ++
Sbjct: 1302 QCVDLQMFNREADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSLMAQDK 1358
Score = 170 bits (431), Expect = 4e-40
Identities = 243/1301 (18%), Positives = 483/1301 (36%), Gaps = 87/1301 (6%)
Frame = +1
Query: 2557 SWIDEKGKLLATLVPGRDIEEVE---IMKHRFDTLEQDMKNQE-----AKVTNVNDLARQ 2712
SWI +K L +E ++ + + T+E+ K +E A +N L +
Sbjct: 303 SWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPKYKERSEIEALYFTINTLLKA 362
Query: 2713 LLNVEHPNSDDILHRQNKLNARWAQL------RDMVDQKRNELERAHRLETFRIDCQETV 2874
L + D L N + W L R++ + L R +LE ++ + + +
Sbjct: 363 LNQPPYNPQDGQL--VNDIEKAWQILEYAEHHREVALRDEQLLLRQEKLENYKFEKKSVL 420
Query: 2875 T--WIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERER 3048
++++ +VL D L + +K +S D+ A + + L A++++RE
Sbjct: 421 REGYLKEMIQVLSDPRYL-RQVDATLKKHEAISA---DILARVERFNDLTAMAEELDREN 476
Query: 3049 PQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVA 3228
+ +R + + W L + + L + +L LR++ + Q+Q A
Sbjct: 477 YHGKERVRRREQEVMAKWRQLLELLENQRLNLSQMSNLMNLLREIASTTEAVRELQQQFA 536
Query: 3229 SEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAG 3408
SE+ L E+LL H+ +++ Y E K+ + + L QRLA
Sbjct: 537 SEDVGPHLLGVEELLQAHSLQELQVNTYGETLKRFNRQALPYKSSEHKDAAL-LAQRLAD 595
Query: 3409 LQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAEN 3588
L+E + EL R R+ L + N F+ D E L ++ + L +
Sbjct: 596 LEEAYSELLRRSAARRARLEEARNFHHFMEDYDNEESWLVDKQRICKTGITAKDLRAVLS 655
Query: 3589 QLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQE 3768
++H+ + + K + G +L + H + +I + ++ E A +
Sbjct: 656 LQQKHKALEDEIKSRKPKSGQMSTAGKRLIGEQHPRSSEIQSRIDSLAEHWQALEALVEL 715
Query: 3769 VLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETY-RDAKTITSKFVRHQAFQSELAA 3945
++L+DA QF +D +E W+ EKM Y D + + RH+ Q EL A
Sbjct: 716 RRRQLEDAAEAYQFYTDANEAESWLNEKMALVNSRDYGNDEPSAQALLQRHRDLQGELNA 775
Query: 3946 NK-------ERLDQLKHAAI---NLGDDKPEYHGTIDPQIEE--------------LATQ 4053
++ D+L A I L +PE P++E+ +
Sbjct: 776 YSGDILNLNQQADKLIKAGICTLELSAAEPEL-----PEVEQEEWVNETRLVPKEVWEDE 830
Query: 4054 WDEL---EKTTEEK------------GQKLFDANRQQLYVQSIADMKEWATQLENEM--- 4179
W E +K TE K GQ + + + ++S + W + +N +
Sbjct: 831 WVEKLEHKKVTETKMLPHVKSLFPFEGQGMKMDKGEVMLLKSKTNDDWWCVRKDNGVEGF 890
Query: 4180 -----TREDQPGDLTTVNVAMQK-------------QHLIETEMIKKAQHIDXXXXXXXX 4305
RE +P + + +K + ++ + IK
Sbjct: 891 VPANYVREVEPRPVACIVPKAEKVKSLQKVKKTILVRQVVPVKRIKPVSVAPKPLVQRRT 950
Query: 4306 XXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISER 4485
+ ++++ + + + LQ R LE F F R+ DD + W+ E+
Sbjct: 951 STQSINENADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEK 1010
Query: 4486 LVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEK 4665
+ K+ GE + + R + ++ + +I +GH+
Sbjct: 1011 ERMIKSDE-GEGVDNAKR---KFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIA 1066
Query: 4666 KIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEF 4845
+ +++ WQ L A R+ L + F C EA+ WMSE+ L + D
Sbjct: 1067 RQRQIHQIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLR 1126
Query: 4846 STKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQD 5025
+ + ++H+ L+ ++ D + + + + + RQ +++ ++ +Q
Sbjct: 1127 TVQALQRRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQ 1186
Query: 5026 XXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFAR 5205
+ LL WI + + E+ +D E L ++
Sbjct: 1187 RGSDLRNRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGD 1246
Query: 5206 DTENIGSERVANANDGCDTLIGHGHTDAPTIALWK------DSLNEAWEN----LLELMD 5355
D +E V G G + A T+A+ + D+++ W LL+ +D
Sbjct: 1247 DIRAHDTEFVEVIQLGKQLSDGKPNM-AETVAVIERLKAEQDAIHRGWAEKQKWLLQCVD 1305
Query: 5356 TRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAA 5535
+ EA ++ D ++ E ++LG V A+ ++H ++ K + A
Sbjct: 1306 LQMFNREADKI---------DATTKSHE-AFLEYNNLGASLDEVEAILKRHLDFEKSLMA 1355
Query: 5536 IGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFK 5715
+ + +A +L D IG R ++V+ + ++ R L + D K
Sbjct: 1356 QDKILKGFSDNADKLISNDHYDSKY-IGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHK 1414
Query: 5716 FMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGR 5895
F DL +W+ + K + E +D+S + + HQ+ + E+ A E G+
Sbjct: 1415 FAAEADDLKVWLQD-KTRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQ 1473
Query: 5896 DLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFA 6075
L+ + E+E ++ L +++ ED+ L+ + R A+ +
Sbjct: 1474 ALVQAGNRVP-EVESRVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDE 1532
Query: 6076 QEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL 6198
+ L S + G +L LI K + E +++ L
Sbjct: 1533 LDAALRSGDVGNDLRSCKDLINKQQILESEITIWDQKVAEL 1573
Score = 144 bits (362), Expect = 4e-32
Identities = 136/689 (19%), Positives = 287/689 (40%), Gaps = 5/689 (0%)
Frame = +1
Query: 4018 TIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP 4197
+++ + + + +DEL++ +++ L D+ + + D ++W + E + ++
Sbjct: 961 SVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSDEGE 1020
Query: 4198 GDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQ 4377
G V+ A +K T++ ++ ++ +L+ I A + + + Q
Sbjct: 1021 G----VDNAKRKFEKFITDLSAASKRVEEIDGAVDTFRRQGHSQLDKIIARQRQIHQIWQ 1076
Query: 4378 RLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQ 4557
RL R K+LE + F R D+ K+W+SE+++ + L LQ+ Q
Sbjct: 1077 RLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQRRHQ 1136
Query: 4558 LLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLG 4737
L E+ E +N++ G + + A + QE++ WQ++++ D + +
Sbjct: 1137 NLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLRNRI- 1195
Query: 4738 ESEKAHQFLYDCGEAE-AWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTI 4914
ESE Q + + AW+ + + DE +D + N +KKH L DI
Sbjct: 1196 ESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHDTEF 1255
Query: 4915 RALATKAHKFVEEKSPLTEQIQVRQAQIEKLYA---GLQDXXXXXXXXXXXXXXXYALHR 5085
+ + + K + E + V IE+L A + +R
Sbjct: 1256 VEVIQLGKQLSDGKPNMAETVAV----IERLKAEQDAIHRGWAEKQKWLLQCVDLQMFNR 1311
Query: 5086 EIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANA-NDGCDT 5262
E D + E G + V+ + +R F + + +++ +D D
Sbjct: 1312 EADKIDATTKSHEAFLEYNNLGASLDEVEAILKRHLDFEKSL--MAQDKILKGFSDNADK 1369
Query: 5263 LIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEK 5442
LI + H D+ I ++ + + + + R ++L+AS+ HKF + D + +K
Sbjct: 1370 LISNDHYDSKYIGDRRNQVLGKRKAVKDRAFERKRLLQASKDFHKFAAEADDLKVWLQDK 1429
Query: 5443 THAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGS 5622
T D+ RD S++ +KHQ + +++ A Q+ + +D L AG++ ++ S
Sbjct: 1430 TRIAGDENYRDLSNLPRKLQKHQAFERELRANEGQLRNVTKDGQALVQ--AGNRVPEVES 1487
Query: 5623 RESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVS 5802
R +++ K W+ L L + + +L + + + D +DE+ + S + D+
Sbjct: 1488 RVADLNKRWKDLLTLSEDKGRKLEQAASQREHNRSLEDAKKKVDELDAALRSGDVGNDLR 1547
Query: 5803 GVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMR 5982
+ L+N Q L++EI ++ +S G D+ + H+ + IE +L ++
Sbjct: 1548 SCKDLINKQQILESEITIWDQKVAELVSTGDDMAHGGHFNAQNIEAGTKELQQRFKDLRD 1607
Query: 5983 RWEDRWEYLQLILEVYQFARDAAVAESWL 6069
+ R L+ L ++F + W+
Sbjct: 1608 PTQRRRAKLEESLNYHKFVFELDSEFQWI 1636
Score = 85.9 bits (211), Expect = 1e-14
Identities = 68/309 (22%), Positives = 132/309 (42%), Gaps = 1/309 (0%)
Frame = +1
Query: 5284 DAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDD 5463
+A ++ + +N+ ++ L E+ R +LE S L FY +C D + EK + D
Sbjct: 958 NADSVEKRQQRINQTYDELQEMAQKRHALLEDSIHLFGFYRECDDFEKWMKEKERMIKSD 1017
Query: 5464 LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALD-IGSRESEVV 5640
G V RK + ++ D++A ++V +I+ R G LD I +R+ ++
Sbjct: 1018 EG---EGVDNAKRKFEKFITDLSAASKRVEEIDGAVDTFR--RQGHSQLDKIIARQRQIH 1072
Query: 5641 KAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLM 5820
+ W+ L R L S + F + +WM E ++++ D+ V+ L
Sbjct: 1073 QIWQRLNNAKAQREKSLEGASSVELFNRTCDEAKVWMSEKMLQLDTAVITPDLRTVQALQ 1132
Query: 5821 NNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRW 6000
HQ+L+ E+ E+ N LG + N + + ++ ++ +R D
Sbjct: 1133 RRHQNLERELAPVEDKVNRVTYLGNSVKNAYPAEKDNVNARQQEVQDMWQQVQQRGSDLR 1192
Query: 6001 EYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQE 6180
++ + F A V +W+ + + L + E R++E L+KKH A +
Sbjct: 1193 NRIESEVGQQVFNNSAKVLLAWIDSVKDQLNADESARDVETANNLLKKHNDLGDDIRAHD 1252
Query: 6181 ERFLALEKL 6207
F+ + +L
Sbjct: 1253 TEFVEVIQL 1261
Score = 43.1 bits (100), Expect = 0.093
Identities = 47/212 (22%), Positives = 92/212 (43%), Gaps = 20/212 (9%)
Frame = +1
Query: 5686 RLMDTS-DLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVE---LLMNNHQSL----- 5838
+LMD ++ + +LL W+ + E+ ++ P + G++ L ++++
Sbjct: 283 QLMDADRKKMQYEGLTTNLLSWIRQKTLELEQRDLPNSLEGIQRELLAFKEYRTIEKPPK 342
Query: 5839 ---KAEIDAREENFNACISLGRDLLNRKHYAS------SEIEK--KLIKLTTERAEMMRR 5985
++EI+A N + LN+ Y ++IEK ++++ E+ R
Sbjct: 343 YKERSEIEALYFTINTLLKA----LNQPPYNPQDGQLVNDIEKAWQILEYAEHHREVALR 398
Query: 5986 WEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKS 6165
+++ Q LE Y+F + + + E +L L Y R ++ T+K KHEA
Sbjct: 399 -DEQLLLRQEKLENYKFEKKSVLREGYLKEMIQVLSDPRYLRQVDATLK---KHEAISAD 454
Query: 6166 AFAQEERFLALEKLTTFELKETQHREEETAKR 6261
A+ ERF L + +E H +E +R
Sbjct: 455 ILARVERFNDLTAMAEELDRENYHGKERVRRR 486
>gi|34856723|ref|XP_238278.2| similar to Spectrin beta chain, brain 4
(Spectrin, non-erythroid beta chain 4) (Beta-V spectrin)
(BSPECV) [Rattus norvegicus]
Length = 3530
Score = 698 bits (1801), Expect = 0.0
Identities = 542/2128 (25%), Positives = 966/2128 (44%), Gaps = 62/2128 (2%)
Frame = +1
Query: 76 FERSRIKALADERELVQKKTFTKWVNS--HLVRVSCKVQDLYMDMRDGKMLLRLLAVLSG 249
+E ++ L + +Q+KTF W+N+ L RV ++Q+LY ++ DG LLRLL ++SG
Sbjct: 61 YEIGHVRKLQAQHTHMQEKTFINWINNIFRLGRVGIRIQNLYTELADGAHLLRLLELISG 120
Query: 250 ERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRF 429
E LP P+PG++R+H LEN L FLR + V + +G +IVDG+ L LGL+W IILRF
Sbjct: 121 EALPAPSPGRLRVHFLENNSHALAFLRAK-VPVPFIGPENIVDGDQSLILGLLWVIILRF 179
Query: 430 QIQDITFEDAD---NHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHK 600
QI I+ + + + SAKEALL+WCQ +TA Y NV++ +FS SW DGLAFNAL+H
Sbjct: 180 QISHISLDREEFGASAALLSAKEALLVWCQRQTASYSNVDITDFSRSWSDGLAFNALLHA 239
Query: 601 HRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYY 780
HRPDL+DY +L LYNL AF AE QLG+A+ LDAEDV PDE+SI+TYV YY
Sbjct: 240 HRPDLLDYGSLSLDRPLYNLSFAFRVAEQQLGIAQLLDAEDVAARHPDERSIMTYVSQYY 299
Query: 781 HYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNL 960
HYF++L+Q +R+ KV+ +L E + + +YE L++DLL WI K L + F ++L
Sbjct: 300 HYFSRLQQGQTARRRLAKVLLQLQETEVLQAQYEQLAADLLCWIEEKQMQLEAQDFPDSL 359
Query: 961 EGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINR 1140
+++ L+ F +R QEKPP+ ++G E LLF LQ+ +RA N+RPF+PREG A++ +
Sbjct: 360 PAMRQLLSAFASFRAQEKPPRLQQQGASETLLFQLQTTLRAQNRRPFLPREGLGPAELAQ 419
Query: 1141 AWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFG-ND 1317
W LE+ E R ++++L++ E+L+ LA RF KA RE++L + ++++ Q D
Sbjct: 420 CWAELERVEASRSQAMQQKLLQLERLDTLARRFQCKASHRESFLNDAEQMLEQARASLTD 479
Query: 1318 LSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXX 1497
++VEAAT++ +E + E R YH A + R++ +
Sbjct: 480 PATVEAATQRLNMLEAGLLPQEGRFQALGEMADILQQEEYHSWADVACRQKEITGRWRRL 539
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
R L + A+ + ++ S L +V LLQ H LL
Sbjct: 540 LQCLQEERKCLAGTQAVLSLLQEVEAATDQLGELQGLAGSTACEPQLAEVVLLLQSHDLL 599
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E+ ++ VN + Q + D G+ + T+ ++ L + + ++ L
Sbjct: 600 EAQVSAHRTHVNRLVHQTAQL---DSSQGTSVQ-----TLQTKALALDELHHSVVSLVRT 651
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
R+ LE + QF E E ++E Q++ GRD+ +++ L KHK E L
Sbjct: 652 RRTLLEQTLQRAQFLHSCEEEEAWLQEHRQLVEKAAPGRDLTQIANALQKHKALETELHR 711
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
+ L G+ L + + R ++ L +A R+ RL + Q+
Sbjct: 712 HQAVCIDLMQRGRNLSVKEPLTQPDPLERAEAVQGIWQLLWTGAARRRTRLQTALLVGQY 771
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES 2397
F+D + +L + + S GKD+ + LL++H + L F ++ L +A +
Sbjct: 772 FSDLAEAASWLLQRQKQLESASYGKDQSDSEALLQQHLRLEQGLCAFAVDLRELEDQARA 831
Query: 2398 L---------------PQEAREHPDIRQRL---------------------------DTT 2451
P+ P++ L
Sbjct: 832 AAALVSQMVHTGTREGPRHVPPTPNVLSALGLPGEDPRTAPQAEYDFHFDSNAILQAQAD 891
Query: 2452 LKQKAE-LENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEI 2628
L+Q E L L++L + RL + ++L+ YS ++SW++ + L TL P D +E+
Sbjct: 892 LRQNYENLRALAKLHRARLEETVTLFSFYSSCRELQSWLEAQTALFQTLQPQGD--NLEV 949
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
+ +++ + + + A QL + I +Q +L RW QL + ++
Sbjct: 950 TQLKYENVLMTLATGKGHWEEAISTAEQLKQRCPGHISKIQQQQEELKHRWQQLEALKEE 1009
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
K +L RA + + QE+ V+ +AL SG R L ++ +
Sbjct: 1010 KLLQLTRAMEVCSL---LQESEPTRAQLLSVISRLEALGTRSSG--DSHRTLQQTQQKVL 1064
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
++ K+ K ++ P E + + E + + + +V + + ++ +QR
Sbjct: 1065 VLEKKISYCQKATIELMESGPAEGRLLWEQVLMLQSLLKQAQGQVAQ-QVQVQTKDRVQR 1123
Query: 3169 -FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMG 3345
L++ W Q Q+ S+E+ + +A A+QLL +H A+REE + E +++ A G
Sbjct: 1124 GILQESQKLLLWAEGIQAQLCSKEQLEDVASAQQLLRKHGALREETCLWKERLQQLEAQG 1183
Query: 3346 DRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
V + PQ+ + L L + ++L+ +W+ RQ L GL LQ F ++
Sbjct: 1184 QLVAVSGS-PQFQEVASALRLLGQHSQQLKALWEQRQQKLWAGLELQRFGQEVDSFTATC 1242
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
+ E L D++ + + +A++ L++HQ + + + G++L + A +
Sbjct: 1243 ASHEASLQLDNLGEDIREAQSLLQQHQGLGWLHSSLGSRAETLWARGEKLLLNHPTAVHR 1302
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
I + + + +E++ + +L +L LQ++ + L W+EEK R DE +
Sbjct: 1303 IRELLHSAQAQWARVQERSDQRRGQLLASLQLQEWKQAAEGLMLWMEEKWPRVADEGPQT 1362
Query: 3886 AKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDEL 4065
I H+ +SEL A+ + ++ L+ L P I +++ L +W+EL
Sbjct: 1363 GSNILQ---WHKITKSELLASHKYMEDLQQTGKELLHSNPYAQEDIQDRLQSLNHKWEEL 1419
Query: 4066 EKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLI 4245
T E+G +L +Q ++ + D++ LE + + DL + + +Q QH
Sbjct: 1420 SHKTAEQGDRLPQTRQQGQLLELLQDVRGMMEHLEGALQSTETGQDLCS-SRRLQTQH-- 1476
Query: 4246 ETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERK 4425
++ K+Q + + I Q++ + LQ+ L R++ L+
Sbjct: 1477 -RQLEGKSQAL-ASKMAALISQTHNVFTSWTILEESQKCQQRFKSLQSKLATRQQQLQAS 1534
Query: 4426 KAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQI 4605
+F + E W++E + + D LQ+
Sbjct: 1535 VELHKFNLLSNLELTWVAEHMPSTSPIYPAQCWHDAQSLQRK------------------ 1576
Query: 4606 CNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAE 4785
+ Q ++++ Q+L W EL++A + R L ++ ++L + E E
Sbjct: 1577 -HKAQHILEQ-----------CQKLEGHWAELEQACEGRAHCLQQAVIFQRYLLNVSEME 1624
Query: 4786 AWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPL 4965
W+ E+ + + G +E +T I+KH+ L + H + + P
Sbjct: 1625 TWVEEKLPLVSSRDYGSNEEATFGLIRKHQVLCPE---------------HLHLGDSGP- 1668
Query: 4966 TEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWI-ADKEVVAGSQ 5142
R Q+ ++ + RE +DL W+ + K+VV G
Sbjct: 1669 -GGGPQRDEQVANIWG--TPGYHHRGQELEGTLRLHEFMREAEDLQSWLDSRKQVVRGEH 1725
Query: 5143 ENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLN 5322
G+D+EHV L F +F E G++RV ++L+ GH+ A + L
Sbjct: 1726 GFGEDHEHVLQLCTEFTKFQHQVET-GAQRVETCRQLAESLLELGHSAAHKSHQRQQDLQ 1784
Query: 5323 EAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR 5502
AW L +L + +L + + + D + LS+I EK +P+D+ +D V +
Sbjct: 1785 AAWCELWQLTQAQGLLLSDAETTLRVHRDLLEILSQIQEKATNLPNDVAQDLHGVEKQLQ 1844
Query: 5503 KHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDART 5682
+H+ +++A + +Q+ ++ + ++ + ++ V +AW L+ + R
Sbjct: 1845 RHEGLERELAGMEQQLQELLKAGGNVQK-LCPQALATVQQKQQAVTQAWEALQLRMEQRK 1903
Query: 5683 SRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDARE 5862
++L L +F VRD W+ V E+ ++ + S + L + HQ L AE+ ARE
Sbjct: 1904 AQLEQAYLLVRFHTAVRDYTSWVASVHLELQMEDDSWEPSSILLRLRAHQWLWAELKARE 1963
Query: 5863 ENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFAR 6042
E +G+ L ++++ L L +R ++ + W + E LQ L+ + R
Sbjct: 1964 ELQEQGTKMGQQALLVAR-TPTKVQDGLQTLQEKRDQVFQAWALKQERLQATLQEQRLLR 2022
Query: 6043 DAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLAL-EKL---- 6207
+L + G ++EE +LI+K F+K Q+++ AL E+L
Sbjct: 2023 QG--------DHLAFLKASGLGSSVEEVEQLIRKLVIFQKVLALQDKKESALCEQLKMIP 2074
Query: 6208 ------TTFELKETQHREEETAKRRGPA 6273
+ ++E + + +E A+ RG A
Sbjct: 2075 SPKGQNLVYHVQERRAQVKELAESRGQA 2102
Score = 431 bits (1108), Expect = e-118
Identities = 416/1822 (22%), Positives = 773/1822 (41%), Gaps = 35/1822 (1%)
Frame = +1
Query: 850 MENDKMINRYETLSSDLLEWINAKIQLLNERH-FENNLEGVQRQLTEFNDYRTQEKP--P 1020
+E ++ + + DL W++++ Q++ H F + E V + TEF ++ Q +
Sbjct: 1694 LEGTLRLHEFMREAEDLQSWLDSRKQVVRGEHGFGEDHEHVLQLCTEFTKFQHQVETGAQ 1753
Query: 1021 KFDEKGEL-EVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLK-- 1191
+ + +L E LL SA ++QR D+ AW L + + L+L
Sbjct: 1754 RVETCRQLAESLLELGHSAAHKSHQRQ---------QDLQAAWCELWQLTQAQGLLLSDA 1804
Query: 1192 EELIRQEK-LEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETD 1368
E +R + L ++ ++ KA T V+QD L VE ++HE +E +
Sbjct: 1805 ETTLRVHRDLLEILSQIQEKA-------TNLPNDVAQD-----LHGVEKQLQRHEGLERE 1852
Query: 1369 IFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAI 1548
+ E++ A + ++++ V R+ +LE + +
Sbjct: 1853 LAGMEQQLQELLKAGGNVQKLCPQALATVQQKQQAVTQAWEALQLRMEQRKAQLEQAYLL 1912
Query: 1549 QKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQ 1728
+ + L ED + L+ H L +++ E
Sbjct: 1913 VRFHTAVRDYTSWVASVHLELQMEDDSWEPSSILLRLRAHQWLWAELKAREELQEQGTKM 1972
Query: 1729 AQRF----RNPDGPDGSGYKPVEPG--TIDERSDVLQKRY---KELLDLAAERKRRLEDN 1881
Q+ R P V+ G T+ E+ D + + + +E L + +R L
Sbjct: 1973 GQQALLVARTPT--------KVQDGLQTLQEKRDQVFQAWALKQERLQATLQEQRLLRQG 2024
Query: 1882 KRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRL 2061
L + + L ++E EQ++ R +V +LA E+ L + K +
Sbjct: 2025 DHLA--FLKASGLGSSVEEVEQLI------RKLVIFQKVLALQDKKESALCEQLKMIPS- 2075
Query: 2062 DVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVD 2241
P N+ + E R + KEL+ SR + L + F A V+
Sbjct: 2076 ------------PKGQNLVYHVQERRAQV---KELAESRGQALRTSLMIGNFTRTATQVE 2120
Query: 2242 RYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREH 2421
++ + L+ + + + L+KH E+Q +Q + + + E L ++ H
Sbjct: 2121 DWIQERLQQLRACSPLGNLKDYLKHLRKHQAFRAEVQAHEQIVTSVAKQGEGLLSQS--H 2178
Query: 2422 PDIR---QRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLAT 2592
P R QRL+ +L L+ Q L D + + AD E+WI EK +++
Sbjct: 2179 PQAREVSQRLEALWDLWEKLRQAVTLQGQALEDRCNFLEFLQSADLAETWIQEKERMVDG 2238
Query: 2593 LVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLN 2772
G ++E + + L+ + + ++ + +L+ QL N S+ I RQN+LN
Sbjct: 2239 CDVGLNLEHCLQLCRQVCKLQVTV--DDTRIRRIKNLSLQLKNQGPEESEAICQRQNQLN 2296
Query: 2773 ARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL 2952
R + R LE A LE R+ + +++ + + ++L L G L
Sbjct: 2297 NRPVLEGEGSGGGRGRLEAA--LERHRLSSE-----LDNIIEQIREKESLAQALEGTEGL 2349
Query: 2953 QR---RLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKV 3123
+R R M+++++ IQ +++SL + E P+ +R + + W + K
Sbjct: 2350 ERISWRQKMLQQEMDLIQTQVESLGGRVSRLCEENPEATGGLRHKQQEMMDSWWKVWHKA 2409
Query: 3124 REHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEI 3303
R+ LD ++Q+ L Q W Q ++A + P S +L +H A + E+
Sbjct: 2410 RKWRELLDVGHEVQKLQTMLQDLQDWAQGLQAEMARQATPCSPVRILYMLEEHQAHKVEL 2469
Query: 3304 DGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNL 3483
D + +R+MG R+ P +RQ LA +++ LQ W RQ L Q L
Sbjct: 2470 DVRTDSLNLVRSMGQRLLASGY-PLASGIRQPLAAVEQELSGLQASWQGRQQQLQQALEQ 2528
Query: 3484 QMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMF 3663
Q+ L ++ E L +E L +++ L E L +H+ + EKI A+
Sbjct: 2529 QLCLSSVEKVEHWLDSEEASLTYEEVADPLVTVEILLSKHKRREQGLKVQAEKISALEAT 2588
Query: 3664 GDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI 3843
L Q GH A + + + + R A E+A+ ++L++ L++FL D E+ W+
Sbjct: 2589 AHSLHQGGHSEAHSVLDRCQALLLRMDALTEQARARGRQLEELQKLRKFLQDSSEVATWL 2648
Query: 3844 EEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTI 4023
EK + A +E +D T+ ++ + Q Q+EL A+ + +L+ L TI
Sbjct: 2649 REKNLVALEEGQQDPTTMQAQLQQQQNLQAELDASVHQRQELQMEGQELLQGGHPASETI 2708
Query: 4024 DPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGD 4203
Q+EEL W EL+ + K +L A++ + + ++K W +E E+ + D
Sbjct: 2709 RGQLEELGGLWAELQTNCQRKMARLQGASKVLHLQRMLRELKNWLEPMEAELRAPVRSQD 2768
Query: 4204 LTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA--VQEQ-- 4371
L V + Q +E + ++A+ + + HRLA V+EQ
Sbjct: 2769 LPRVGELLGAQEELEAAVDRQARQVQELQGQAQACFQ---------EGHRLAKDVEEQAG 2819
Query: 4372 --LQRLQA---PLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCH 4536
LQR Q PL +RR +LE ++ QF RDVD+E W+ E+L A AQ+ G+SL
Sbjct: 2820 QLLQRFQGLWEPLQERRASLEAQRLLLQFFRDVDEEMAWVQEKLPSATAQDYGQSLGTVR 2879
Query: 4537 RLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVK 4716
LQ+ Q L NEI NH+ + G +L+ GH ++Q+L A L+
Sbjct: 2880 HLQEKHQNLENEISNHKALSQVVTGTGHKLVQAGHFAAEEVAARVQQLEVALNHLETEAA 2939
Query: 4717 DRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDID 4896
R L ++ +A Q L + EA +W++E+ + ++ G+D +T+ +++ E D++
Sbjct: 2940 RRGRMLQQALEAQQTLVELLEAGSWLAERGHILDSEDLGQDTEATQALLRRLETTTRDLE 2999
Query: 4897 KFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYA 5076
F+ I L + P + ++ + + + +A L Y
Sbjct: 3000 GFSSRIEQLQQTVALLESGQGPGSPRVLAQLQAVREAHAQLLQRAEGRGQALREQLHLYQ 3059
Query: 5077 LHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGC 5256
L +E L W+ K VA SQ+ GQD E +++L++ F F R+ +++G ++ +
Sbjct: 3060 LEQEALLLDAWLTTKLTVAESQDYGQDLEGIKVLEDMFDAFNREVQSLGQAKMQTLRELM 3119
Query: 5257 DTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIM 5436
+L P I K + WE L + + R + L A+R L F + +
Sbjct: 3120 ASLERGAPRFYPQIQAQKCRVQATWERLNKAIKARTENLAAARDLRSFEQAASELQGWMQ 3179
Query: 5437 EKTHAMPDDLG-RDSSSVGALSRKHQ---NYLKDIAAIGEQVAQIERDAAELRDGYAGDK 5604
E T + + D S L ++ Q +++ I +V++++ +A L + +
Sbjct: 3180 ETTTLLEGEFQVHDLSPAQPLLQQQQQQRRLQREVRVIENEVSRVQTEAQRLGQHHPLAQ 3239
Query: 5605 ALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQE 5784
+G ++V AW +L + +L+ + F+ R+LL+W E + ++S++
Sbjct: 3240 G-SLGEWLTKVQGAWANLEAKVQEWSQKLLQATQGHTFLGSCRELLVWAQEKQELLSSEK 3298
Query: 5785 RPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTE 5964
+ +DV G + L+ H+ L+ EI G+ LL++ H+ S E+ + + +L
Sbjct: 3299 QAEDVVGAKQLLEQHEELEQEIQECCLQAQNARQEGQRLLDKGHFMSLEVAECMQELERH 3358
Query: 5965 RAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKK 6144
E+ W R + L+ + Q + +AE+WL + E L+ G ++ + +L+ +
Sbjct: 3359 VQELQVAWALRGQRLEQNWSLQQLRQRLELAEAWLTSCECLLLDPSCGHSVLDVERLLYR 3418
Query: 6145 HEAFEKSAFAQEERFLALEKLT 6210
+ EK A EE+F L+ +T
Sbjct: 3419 QDGLEKLLAAHEEKFTQLQMMT 3440
Score = 164 bits (416), Expect = 2e-38
Identities = 298/1504 (19%), Positives = 597/1504 (38%), Gaps = 54/1504 (3%)
Frame = +1
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
E+ L+ + EL R L+ ++ +V+E+E ++E+ ++SS D G +
Sbjct: 1584 EQCQKLEGHWAELEQACEGRAHCLQQAVIFQRYLLNVSEMETWVEEKLPLVSSRDYGSNE 1643
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
L+ KH+ L +L G +DE + P
Sbjct: 1644 EATFGLIRKHQ----VLCPEHLHLGDSGPGGGPQRDEQVANIWGTPG------------- 1686
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSE-DVGKDEGTVQLLLKKHDDV 2337
R + L G + ++F +A+D+ +L +V+ E G+D V L +
Sbjct: 1687 --YHHRGQELEGTLRLHEFMREAEDLQSWLDSRKQVVRGEHGFGEDHEHVLQLCTEFTKF 1744
Query: 2338 HDELQNFDQHIKVLHAKAESLPQ--EAREHPDIRQRLDTTLKQKAELENLSQLRKQRLID 2511
+++ Q ++ AESL + + H QR EL L+Q + L D
Sbjct: 1745 QHQVETGAQRVETCRQLAESLLELGHSAAHKS-HQRQQDLQAAWCELWQLTQAQGLLLSD 1803
Query: 2512 ALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVT- 2688
A + +++ D + S I EK L V +D+ VE R + LE+++ E ++
Sbjct: 1804 AETTLRVHRDLLEILSQIQEKATNLPNDV-AQDLHGVEKQLQRHEGLERELAGMEQQLQE 1862
Query: 2689 ------NVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETF 2850
NV L Q L + +Q + W L+ ++Q++ +LE+A+ L F
Sbjct: 1863 LLKAGGNVQKLCPQALAT-------VQQKQQAVTQAWEALQLRMEQRKAQLEQAYLLVRF 1915
Query: 2851 RIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGA---IQAKLDSLHK 3021
++ +W+ L+ D S +++L R + +L A +Q + + +
Sbjct: 1916 HTAVRDYTSWVASVHLELQMEDDSWEPSSILLRL-RAHQWLWAELKAREELQEQGTKMGQ 1974
Query: 3022 EADDIER--ERPQEA-QAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
+A + R + Q+ Q ++E ++ Q W + +++ +A L E QR LR DH
Sbjct: 1975 QALLVARTPTKVQDGLQTLQEKRDQVFQAWALKQERL---QATLQE----QRLLRQGDHL 2027
Query: 3193 QAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTD 3372
A+L A+ S+ E EQL+ + ++ + A KK A+ +++ +
Sbjct: 2028 -AFLKASGL-------GSSVEEVEQLIRKLVIFQKVL---ALQDKKESALCEQLKMIPSP 2076
Query: 3373 PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAK 3552
+ + +QE +++ + ++R L L + F R A Q E + ++ L
Sbjct: 2077 KG----QNLVYHVQERRAQVKELAESRGQALRTSLMIGNFTRTATQVEDWIQERLQQLRA 2132
Query: 3553 DDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNID 3732
+L+ L++HQ F + A+++ + +V G+ L H A ++ ++ +
Sbjct: 2133 CSPLGNLKDYLKHLRKHQAFRAEVQAHEQIVTSVAKQGEGLLSQSHPQAREVSQRLEALW 2192
Query: 3733 ERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFV 3912
+ R+ + L+D + +FL D WI+EK R D +
Sbjct: 2193 DLWEKLRQAVTLQGQALEDRCNFLEFLQSADLAETWIQEKE-RMVDGCDVGLNLEHCLQL 2251
Query: 3913 RHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQ 4092
Q + ++ + R+ ++K+ ++ L + PE I + +L + LE G+
Sbjct: 2252 CRQVCKLQVTVDDTRIRRIKNLSLQLKNQGPEESEAICQRQNQLNNR-PVLEGEGSGGGR 2310
Query: 4093 KLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQ 4272
+A ++ + S ++ Q+ + + + +Q +++ EM
Sbjct: 2311 GRLEAALERHRLSS--ELDNIIEQIREKESLAQALEGTEGLERISWRQKMLQQEMDLIQT 2368
Query: 4273 HIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRD 4452
++ +P+ ++ + + + ++ R+ L+ +
Sbjct: 2369 QVESLGGRVSRLCEENPEATGGLRHKQQEMMDSWWKVWHKARKWRELLDVGHEVQKLQTM 2428
Query: 4453 VDDEKLWISE-RLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI 4629
+ D + W + +A+ + + L+++ Q E+D +N + + GQ L+
Sbjct: 2429 LQDLQDWAQGLQAEMARQATPCSPVRILYMLEEH-QAHKVELDVRTDSLNLVRSMGQRLL 2487
Query: 4630 DEGH--ANG-----PAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEA 4788
G+ A+G A E+++ L+++WQ R+ L ++ + L + E
Sbjct: 2488 ASGYPLASGIRQPLAAVEQELSGLQASWQ-------GRQQQLQQALEQQLCLSSVEKVEH 2540
Query: 4789 WMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVE------ 4950
W+ +E + +E + + + KH+R + + A+ I AL AH +
Sbjct: 2541 WLDSEEASLTYEEVADPLVTVEILLSKHKRREQGLKVQAEKISALEATAHSLHQGGHSEA 2600
Query: 4951 ------------EKSPLTEQIQVRQAQIE---KLYAGLQDXXXXXXXXXXXXXXXYALHR 5085
LTEQ + R Q+E KL LQD
Sbjct: 2601 HSVLDRCQALLLRMDALTEQARARGRQLEELQKLRKFLQDS------------------- 2641
Query: 5086 EIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTL 5265
++ W+ +K +VA +E QD +Q ++ Q + + +R +G + L
Sbjct: 2642 --SEVATWLREKNLVA-LEEGQQDPTTMQAQLQQQQNLQAELDASVHQRQELQMEGQELL 2698
Query: 5266 IGHGHTDAPTIALWKDSLNEAWENL-LELMDTRAQILEASRLLH--KFYHDCRDCLSRIM 5436
G GH + TI + L W L A++ AS++LH + + ++ L +
Sbjct: 2699 QG-GHPASETIRGQLEELGGLWAELQTNCQRKMARLQGASKVLHLQRMLRELKNWLEPME 2757
Query: 5437 EKTHA--MPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIE----RDAAELRDGYAG 5598
+ A DL R +GA Q L+ AA+ Q Q++ + A ++G+
Sbjct: 2758 AELRAPVRSQDLPRVGELLGA-----QEELE--AAVDRQARQVQELQGQAQACFQEGHR- 2809
Query: 5599 DKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNS 5778
A D+ + ++++ ++ L R + L L +F V + + W+ E +
Sbjct: 2810 -LAKDVEEQAGQLLQRFQGLWEPLQERRASLEAQRLLLQFFRDVDEEMAWVQEKLPSATA 2868
Query: 5779 QERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLT 5958
Q+ + + V L HQ+L+ EI + G L+ H+A+ E+ ++ +L
Sbjct: 2869 QDYGQSLGTVRHLQEKHQNLENEISNHKALSQVVTGTGHKLVQAGHFAAEEVAARVQQLE 2928
Query: 5959 TERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLI 6138
+ R LQ LE Q + A SWL + L S++ G++ E T L+
Sbjct: 2929 VALNHLETEAARRGRMLQQALEAQQTLVELLEAGSWLAERGHILDSEDLGQDTEATQALL 2988
Query: 6139 KKHE 6150
++ E
Sbjct: 2989 RRLE 2992
Score = 58.2 bits (139), Expect = 3e-06
Identities = 78/392 (19%), Positives = 148/392 (36%), Gaps = 38/392 (9%)
Frame = +1
Query: 5296 IALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRD 5475
+A + + W LL+ + + L ++ + ++++ A D LG
Sbjct: 525 VACRQKEITGRWRRLLQCLQEERKCLAGTQ-----------AVLSLLQEVEAATDQLGEL 573
Query: 5476 SSSVGA------------LSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIG 5619
G+ L + H ++A V ++ A+L D G +
Sbjct: 574 QGLAGSTACEPQLAEVVLLLQSHDLLEAQVSAHRTHVNRLVHQTAQL-DSSQGTSVQTLQ 632
Query: 5620 SRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDV 5799
++ + + + L R + L T +F++ + W+ E ++ + +D+
Sbjct: 633 TKALALDELHHSVVSLVRTRRTLLEQTLQRAQFLHSCEEEEAWLQEHRQLVEKAAPGRDL 692
Query: 5800 SGVELLMNNHQSLKAEIDAREENFNACISL---GRDLLNRKHYASSEIEKKLIKLTTERA 5970
+ + + H++L+ E+ + CI L GR+L ++ + ERA
Sbjct: 693 TQIANALQKHKALETELHRHQA---VCIDLMQRGRNLSVKEPLTQPD--------PLERA 741
Query: 5971 EMMRR-WEDRWE-------YLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEET 6126
E ++ W+ W LQ L V Q+ D A A SWL ++ L S YG++ ++
Sbjct: 742 EAVQGIWQLLWTGAARRRTRLQTALLVGQYFSDLAEAASWLLQRQKQLESASYGKDQSDS 801
Query: 6127 IKLIKKHEAFEKS--AFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHI------- 6279
L+++H E+ AFA + R L + L + T R GP H+
Sbjct: 802 EALLQQHLRLEQGLCAFAVDLRELEDQARAAAALVS---QMVHTGTREGPRHVPPTPNVL 858
Query: 6280 ------GSPSRSTPAAETSFGAQDDGAKQGEA 6357
G R+ P AE F + Q +A
Sbjct: 859 SALGLPGEDPRTAPQAEYDFHFDSNAILQAQA 890
Score = 56.2 bits (134), Expect = 1e-05
Identities = 91/537 (16%), Positives = 191/537 (34%), Gaps = 7/537 (1%)
Frame = +1
Query: 1123 IADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQD 1302
+ + A LE R +L++ L Q+ L +L +WL E ++ +
Sbjct: 2924 VQQLEVALNHLETEAARRGRMLQQALEAQQTLVELLEA--------GSWLAERGHILDSE 2975
Query: 1303 NFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXX 1482
+ G D + +A ++ E D+ + R ++ + + V
Sbjct: 2976 DLGQDTEATQALLRRLETTTRDLEGFSSRIEQLQQTVALLESGQGPGSPRVLAQLQAVRE 3035
Query: 1483 XXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQ 1662
R L + + ++ + S+D G L ++ L
Sbjct: 3036 AHAQLLQRAEGRGQALREQLHLYQLEQEALLLDAWLTTKLTVAESQDYGQDLEGIKVLED 3095
Query: 1663 KHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELL 1842
++ +G+ A+ Q R G P I + +Q ++ L
Sbjct: 3096 MFDAFNREVQSLGQ------AKMQTLRELMASLERGAPRFYP-QIQAQKCRVQATWERLN 3148
Query: 1843 DLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKH---K 2013
R L + L F +EL+ ++E +L D+ LL + +
Sbjct: 3149 KAIKARTENLAAARDLRSFEQAASELQGWMQETTTLLEGEFQVHDLSPAQPLLQQQQQQR 3208
Query: 2014 NAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLA 2193
+ +R +E + R+ + L ++ L +++ L+ ++L
Sbjct: 3209 RLQREVRVIENEVSRVQTEAQRLGQHHPLAQGSLGEWLTKVQGAWANLEAKVQEWSQKLL 3268
Query: 2194 GGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIK 2373
+ + F ++ + + ++SSE +D + LL++H+++ E+Q +
Sbjct: 3269 QATQGHTFLGSCRELLVWAQEKQELLSSEKQAEDVVGAKQLLEQHEELEQEIQECCLQAQ 3328
Query: 2374 VLHAKAESLPQEAR----EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSD 2541
+ + L + E + Q L+ ++ EL+ LR QRL SL +L
Sbjct: 3329 NARQEGQRLLDKGHFMSLEVAECMQELERHVQ---ELQVAWALRGQRLEQNWSLQQLRQR 3385
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQ 2712
+ E+W+ LL G + +VE + +R D LE+ + E K T + + +
Sbjct: 3386 LELAEAWLTSCECLLLDPSCGHSVLDVERLLYRQDGLEKLLAAHEEKFTQLQMMTEE 3442
>gi|25155104|ref|NP_741632.1| SMAll body size SMA-1, betaH chain
spectrin homolog required for embryonic elongation and
morphogenesis; expressed in epithelial cells (470.0 kD)
(sma-1) [Caenorhabditis elegans]
gi|11359811|pir||T42993 probable spectrin beta chain - Caenorhabditis
elegans
gi|2997690|gb|AAC08577.1| beta chain spectrin homolog Sma1
[Caenorhabditis elegans]
gi|14530518|emb|CAB04608.2| C. elegans SMA-1 protein (corresponding
sequence R31.1) [Caenorhabditis elegans]
gi|14530529|emb|CAB00130.2| Hypothetical protein R31.1
[Caenorhabditis elegans]
Length = 4063
Score = 691 bits (1782), Expect = 0.0
Identities = 531/2098 (25%), Positives = 954/2098 (45%), Gaps = 25/2098 (1%)
Frame = +1
Query: 46 DYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKML 222
D D+ N+ FERSRI+ L DER +QKKTFTKW NS L R S ++ DL+ D+ DG ML
Sbjct: 26 DQDEFNNETLYFERSRIRTLQDERVHIQKKTFTKWCNSFLNRASLEIVDLFEDVGDGIML 85
Query: 223 LRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLG 402
++LL ++SG++L KP G+MR+ +EN+ K L FL+ + + LEN+G+ DI+D N RL LG
Sbjct: 86 MKLLEIISGDKLGKPNRGRMRVQKVENLNKVLDFLKKKKIQLENIGAEDILDRNERLILG 145
Query: 403 LIWTIILRFQIQDITFEDADNH-ETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
LIWTIILRFQI I ED + E + AK+ALLLWCQ KTAGYPNV ++NF+TSWR+GLA
Sbjct: 146 LIWTIILRFQIDTIVIEDEEERGERKHAKDALLLWCQRKTAGYPNVRIENFTTSWRNGLA 205
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIH HRPDLVD++ L + + NL AFD AE +L +A+ LDAEDV+V +PDEKSII
Sbjct: 206 FNALIHSHRPDLVDFNRLNPNEHVDNLNHAFDVAEKKLEIARLLDAEDVDVTRPDEKSII 265
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYV YYH+F K K + +RI ++ +LM ++ M + YE ++S+LL WI I+ L
Sbjct: 266 TYVSLYYHHFAKQKTEMTGARRIANIVGKLMVSETMEDDYEHIASELLNWIRVTIKTLES 325
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L G++ + +FN +RT EKPPK+ EKGELE L FT+Q+ +A +++ + P +G
Sbjct: 326 RRFPNSLNGMREEHAKFNQFRTSEKPPKYKEKGELEALFFTIQTKRKAMSRKQYQPPQGL 385
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
+ DI AW L+ AE+ER++ + EL RQEKLEQLA RF++KA++R++WL Q ++ +
Sbjct: 386 FMHDIESAWAQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDSWLRSVQVVLEE 445
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
G S VE KK +AI TDI A E+R YH+ K+ + +
Sbjct: 446 MEHGRSASQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREII 505
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
R+ L + + ++ + + D+G HL+ VEDLL
Sbjct: 506 DRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLL 565
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
KH LL++ IN G ++ A + +K + + + D + +Y L
Sbjct: 566 GKHDLLDAQINAHGSLLSKLSQSANNYIR--------HKEEQFDVLQRKLDEVTAQYNTL 617
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++L R+ LE + L QF D E + E+E++ ++ DI V +KN
Sbjct: 618 VELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNV 677
Query: 2020 ENNLRDLEKYLDRLD--VSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLA 2193
E +++ + R ++G E ++ ++I RL ++ +L+ + L+
Sbjct: 678 E---MEMQTHWARSKGMIAGGERLVQNGQSKEDIQRRLTQMNHRWERLRVAVDALGNWLS 734
Query: 2194 GGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIK 2373
Q+F DA++ + ++ + + ++ S+D+G+DEG + LL++H + +E++ + I
Sbjct: 735 EARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSDIS 794
Query: 2374 VLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSV 2553
L L A Q + Q+ E N+ Q+ Y + V
Sbjct: 795 RLEEMQSQLANSAFHTATTSQSV-----QETEEVNVPQVEMS--------YNYEGNGMRV 841
Query: 2554 ESWIDEKGKLLATLVPG-----RDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLL 2718
KG++LA L R ++ + + + + VT L
Sbjct: 842 -----SKGEVLALLEKSTPEWWRALKRDGTEGYVPANYCKIVPGETVTVTQTTQKTTTTL 896
Query: 2719 NVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTR 2898
S + RQ+K++ + +L+ + D +R L +L F +C E W ++
Sbjct: 897 EGNETKSSVVADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEV 956
Query: 2899 VLEDSDALTNDLSGVMKLQRRLSMMERDL---GAIQAKLDSLHKEADDIERERPQEAQAI 3069
L D + + V +R+ +E D+ G Q K ++ A+D+ E +++ I
Sbjct: 957 SLADEPSPEH----VAAFRRKFDKLEADMKTNGGTQLK--HINDIANDLISEGHGQSRKI 1010
Query: 3070 REDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQS 3249
+I+ +WD L + ++ +L+ + F + + W+ + Q+ + P
Sbjct: 1011 EVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQL--DRNPND 1068
Query: 3250 LAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEE 3429
+ + L + ++I + + V +D + + + +++A L+ +
Sbjct: 1069 VKSLQNLERDLKPLEDKI-------AALEKLAAAVKKDHPE-EAAAIERKIAELRALHAD 1120
Query: 3430 LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQD 3609
L R + L Q +MF + + + + +D P + +AE LK+H +
Sbjct: 1121 LLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYE 1180
Query: 3610 FITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKD 3789
+ ++ G +L + + K+ ++ +N+ + R+ + LK
Sbjct: 1181 LGEQIKDKKYEVEYCQELGRRLL-ERNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQ 1239
Query: 3790 ALSLQQFLSDCDELREWIEEKMIRAQDETYRDA-KTITSKFVRHQAFQSELAANKERLDQ 3966
L LQ F + + + + + + D+ +++ + RH+ +++L A + RL+
Sbjct: 1240 QLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEA 1299
Query: 3967 LKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADM 4146
A ++ + I+ + ++ + + + + ++ ++L + Q + ++
Sbjct: 1300 FSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEV 1359
Query: 4147 KEWA-TQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
W + + M+ +D + + + K E E+I I
Sbjct: 1360 VGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKH 1419
Query: 4324 DELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRD--VDDEKLWISERLVLA 4497
E N++ V Q L+ + K L ++AA Q G D ++D + E
Sbjct: 1420 YESPNVEKIVRQVNAQWGDLKKQV--WNKGLRLRQAADQKGLDRILEDAHAKLDEMQTAL 1477
Query: 4498 KAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQE 4677
+++ G L L + +L E+ + ++ I N G+++ +GH + + +
Sbjct: 1478 NSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQ 1537
Query: 4678 LRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKN 4857
L + +K + RKGDL ES HQ ++D W++E++ + G+ N
Sbjct: 1538 LLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALN 1597
Query: 4858 QIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXX 5037
+KK E+L++++++ I + +A + ++ + QI+ + +++E ++ L+
Sbjct: 1598 MVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRL 1657
Query: 5038 XXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTEN 5217
+ ++ W+ +K S++ G D + + L + + D
Sbjct: 1658 RRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTT 1717
Query: 5218 IGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHK 5397
+ + C L+ +D L ++ L +L + R LE + L++
Sbjct: 1718 Y-RQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYE 1776
Query: 5398 FYHDCRDCLSRIMEKTH-AMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDA- 5571
+ + D I E AM ++ D + L K + + + E+ E A
Sbjct: 1777 YMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAAN 1836
Query: 5572 AELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWM 5751
A LR A D+ ++ + AW L +AR S+L +L +F V + WM
Sbjct: 1837 AILRRN--PPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWM 1894
Query: 5752 DEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSE 5931
+ M ++ +DV V L +H++L EI + + L +K Y
Sbjct: 1895 ADKMANM-PRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERL--KKTYPGGN 1951
Query: 5932 IEK---KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKE 6102
E+ + L E E+ +DR + L+ +++ F +W + S
Sbjct: 1952 AEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDL 2011
Query: 6103 YGRNLEETIKLIKKHEAFEKSAFAQEERFLAL----EKLTTFELKETQHREEETAKRR 6264
+ +L++ L +H A+E F L EK+ T QH E K +
Sbjct: 2012 HINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMIT-----AQHYASEEIKNK 2064
Score = 516 bits (1329), Expect = e-144
Identities = 380/1509 (25%), Positives = 674/1509 (44%), Gaps = 24/1509 (1%)
Frame = +1
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
I R + R++ L L + + Q++ D E E I+E+ ++ S D GR
Sbjct: 708 IQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGR 767
Query: 1975 DIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINK 2154
D LL +H E +R + + RL+ +L + + A + +
Sbjct: 768 DEGAAESLLQRHARLEEEIRAYKSDISRLEEMQSQLANSAF--------HTATTSQSVQE 819
Query: 2155 LKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDD 2334
+E++ + E + Y Y + +RV E + LL K +
Sbjct: 820 TEEVNVPQVE-----MSY-----------NYEGNGMRVSKGE-------VLALLEKSTPE 856
Query: 2335 VHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKA---------------- 2466
L+ V + +P E Q+ TTL+
Sbjct: 857 WWRALKRDGTEGYVPANYCKIVPGETVTVTQTTQKTTTTLEGNETKSSVVADRQHKISND 916
Query: 2467 --ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHR 2640
EL+ L+ +R++ L D + L + Y + D E W E + +L E V + +
Sbjct: 917 YRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKE---IEVSLADEPSPEHVAAFRRK 973
Query: 2641 FDTLEQDMK-NQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRN 2817
FD LE DMK N ++ ++ND+A L++ H S I RQ+K+NA W L + Q+
Sbjct: 974 FDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQHKINAMWDNLERLRKQRGV 1033
Query: 2818 ELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQ 2997
LE R+ F C+ W+ K E D ND+ + L ERDL ++
Sbjct: 1034 RLEATERVADFDTTCESAREWMLSK---FEQLDRNPNDVKSLQNL-------ERDLKPLE 1083
Query: 2998 AKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLR 3177
K+ +L K A ++++ P+EA AI I + + L ++ +E ++ + F
Sbjct: 1084 DKIAALEKLAAAVKKDHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQTQGKEMFES 1143
Query: 3178 DLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVT 3357
L W+ T++ + + P +AEAE+LL +H + E+I + + + +G R+
Sbjct: 1144 ALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLL 1203
Query: 3358 QDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQE 3537
+ +P+ + ++L L L+ ++ R +L Q L+LQ+F R++++ + E
Sbjct: 1204 E--RNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHE 1261
Query: 3538 NYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKK 3717
+L D++ S+E EN LKRH+D +DA + ++ A D + + H + I ++
Sbjct: 1262 AFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQR 1321
Query: 3718 ARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEK--MIRAQDETYRDAK 3891
R++ RR A R A + K+L+ +L Q+ + DE+ W+ EK ++ + D++
Sbjct: 1322 RRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPS 1381
Query: 3892 TITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEK 4071
I + ++H+AF++E+ AN+ R+ Q+ L K ++ + ++ QW +L+K
Sbjct: 1382 AIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKK 1441
Query: 4072 TTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIET 4251
KG +L A Q+ + + D +++ + +DQ DL +V +QK ++E
Sbjct: 1442 QVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQ 1501
Query: 4252 EMI---KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALER 4422
EM K I+ D + + L ++ ++ P R+ L+
Sbjct: 1502 EMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQLL---QRYAAMKGPAQRRKGDLDE 1558
Query: 4423 KKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQ 4602
+ Q DVD E WI+E+ +A +Q+ G +L + + K + L E++ H I++
Sbjct: 1559 SRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDK 1618
Query: 4603 ICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEA 4782
+ ELI H+ + K EL +AW ELK+ ++ R+ + K Q+L+D E
Sbjct: 1619 VLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEV 1678
Query: 4783 EAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSP 4962
E+WM+E+ + ++ G DE + + + KH L D+ + + L K + VE P
Sbjct: 1679 ESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRP 1738
Query: 4963 LTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQ 5142
E+ Q RQ ++ + + L Y RE DL Q I + VA S+
Sbjct: 1739 HVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSE 1798
Query: 5143 ENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLN 5322
E +DYEH++ LQ +F +F + +N GSER + + ++ A + +++L
Sbjct: 1799 EFAEDYEHLKELQSKFDEFKQKVKN-GSERFTSCETAANAILRRNPPFARDVVKKQEALR 1857
Query: 5323 EAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR 5502
AW L E ++ R L + LH+F+ D + + +K MP DLGRD V +L +
Sbjct: 1858 TAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQ 1917
Query: 5503 KHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDART 5682
H+ K+I ++A++ +A L+ Y G A IG R+ + + W L+ D R
Sbjct: 1918 HHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRK 1977
Query: 5683 SRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDARE 5862
L DL F VRDLL W D ++ S D+ E L H L E+DARE
Sbjct: 1978 DMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDARE 2037
Query: 5863 ENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFAR 6042
F ++ G ++ +HYAS EI+ K L + + W R +L ++ + F R
Sbjct: 2038 PEFARLVNDGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQR 2097
Query: 6043 DAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFEL 6222
+A + + ++ L S G ++ + K+ + FEK+ +ER L+ T EL
Sbjct: 2098 EAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDH-TANEL 2156
Query: 6223 KETQHREEE 6249
+ +H E +
Sbjct: 2157 MKARHMESK 2165
Score = 502 bits (1292), Expect = e-140
Identities = 450/2045 (22%), Positives = 850/2045 (41%), Gaps = 107/2045 (5%)
Frame = +1
Query: 850 MENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFD 1029
+E+ + Y S+DL + I +++ F + E ++ ++F++++ + K
Sbjct: 1768 LEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVK----- 1822
Query: 1030 EKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERE--LVLKEELI 1203
E T +A+ N PF K + AW +L + R+ L + EEL
Sbjct: 1823 NGSERFTSCETAANAILRRNP-PFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEEL- 1880
Query: 1204 RQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYE 1383
RF+R + E W+ + + +D G D+ V + + HEA++ +I +
Sbjct: 1881 ---------HRFHRDVDEFEQWMADKMANMPRD-LGRDVKHVHSLWQHHEALDKEIHNSQ 1930
Query: 1384 ERXXXXXXXXXXXXXXNYHDQAK-INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIF 1560
R A+ I R++ + R+ L + + F
Sbjct: 1931 PRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHT-F 1989
Query: 1561 HXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF 1740
+ + + DL H+ D LQ+ L+++ + + ++ + R
Sbjct: 1990 NGKVRDLLAWTDLTISDIQSDL--HIND----LQQAEWLQTEHSRLSHEMDAREPEFARL 2043
Query: 1741 RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAEL 1920
N DG + I ++ +L+ + L A R L + F + ++
Sbjct: 2044 VN-DGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQI 2102
Query: 1921 EHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIP 2100
I + L S G + V + E L L++ LD + EL
Sbjct: 2103 IASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHM 2162
Query: 2101 GSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYD-TLRVMSS 2277
S NI + + + + L++ +R L F +D ++ ++ + T V +
Sbjct: 2163 ESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKA 2222
Query: 2278 EDVGKDEGTVQLLLKK---HDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDT 2448
+D+ + ++ +K+ H + E+ + + + L + +P I R D
Sbjct: 2223 QDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQILQRGNQL-KNLHRNPKIANRCDE 2281
Query: 2449 TLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEI 2628
+ +L + L +A L + ++V +WI+EK L++T G+D+E +
Sbjct: 2282 LSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRL 2341
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
+ R D D E + +N L +L+ + D + Q LN +W L +
Sbjct: 2342 LLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAH 2401
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
R EL A + TF D ++T I +K ++ SD D + V L R+ S +ERD+
Sbjct: 2402 YRTELLAAMEVHTFNRDVEDTDERIHEKVAAMK-SDDYGKDFASVELLVRKQSALERDMS 2460
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
AI KL + K+A I +RP + + + +K++ + W+ L+K KL+ + L +
Sbjct: 2461 AIHQKLIAHDKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYK 2520
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
+L D+ + W + ++ S + P+ A ++L QH + EIDG +E+ + + G
Sbjct: 2521 YLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQ 2580
Query: 3349 RVTQDQTDPQYMFLRQRL-AGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
+ Q+Q P++ QR +Q +L++ W++ + L + L ++ +A Q E L
Sbjct: 2581 ALNQEQ--PEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWL 2638
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
S +E +A+ ++ + + E +K H F T+ EKI A+ D L G+
Sbjct: 2639 SDKETQVARGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRAD 2698
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
I ++ + R + ++ L+D+ +F+ C EL WI K+ A DE++ D
Sbjct: 2699 IVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESFLD 2758
Query: 3886 AKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDEL 4065
+ SK +H AF SEL N++RL ++ L D + Q+ EL + WDEL
Sbjct: 2759 HTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDEL 2818
Query: 4066 EKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLI 4245
+ K Q+L +A + + D+++W ++E E++ +D D+ + + ++K +
Sbjct: 2819 RTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTL 2878
Query: 4246 ETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERK 4425
+TE+ ++ + ++ V+ + L P+ RR+ L
Sbjct: 2879 QTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDA 2938
Query: 4426 KAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQI 4605
+A FQ+ + +++ W+S+R++LA + G+SL LQK L E+D + +N
Sbjct: 2939 QAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDT 2998
Query: 4606 CNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAE 4785
G+++I + H +K + L SA LKE+ R+ L E+ AH++ + EAE
Sbjct: 2999 EQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAE 3058
Query: 4786 AWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPL 4965
W+ EQ M E G+D+ ++ +++ L +++ F + I L +A + +
Sbjct: 3059 QWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHD 3118
Query: 4966 TEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQE 5145
I +Q ++E L+ L + R+ DDL W+ +KE A +++
Sbjct: 3119 AMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAED 3178
Query: 5146 NGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNE 5325
GQD E Q + E+F+ R+ G ERVA + L+ GH +I +
Sbjct: 3179 YGQDLEDCQQIIEQFESTVRELAAAG-ERVAAVQRAQEDLLRSGHPYGASITAKGADVQR 3237
Query: 5326 AWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHA----MPDDLGR-DSSSVG 5490
W ++ E+ + R Q L +R +H+F + L+ + +K +DL R D +SV
Sbjct: 3238 LWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVK 3297
Query: 5491 ALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLC 5670
A ++H ++ + A+ +QVA++ +A L + + D + R ++ + + +
Sbjct: 3298 AQLQRHDEFMHGMKAVEKQVAELCHEAERLWNSFP-DTRHHLEVRRLDMEEQLKDILEAA 3356
Query: 5671 DARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEI 5850
+L L + R+++ WM ++ M S++ P+DV+ E L+ H E+
Sbjct: 3357 KKHLEKLRHMQSLQSYFQEYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEM 3416
Query: 5851 DAREENFNACISLGRDLLNRKHYASSEIEKK----------LIKLTTERAEM------MR 5982
R+ + GR ++ H S EI++K L ++ +RAE+ ++
Sbjct: 3417 QGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQ 3476
Query: 5983 RWEDRWEYLQLILEV--------YQFARDAAVAESWLFAQEPYLI--------------- 6093
+W+ E L LE ++ +AE+ L + +L+
Sbjct: 3477 KWKQNAEQLDSWLEERAGLLGDDWRMVDSVEMAETHLRDFDDFLVTLEAQSEKCDMVKRL 3536
Query: 6094 -----------SKEYGR--------NLEETIKLIKKHEAFEKSAFAQEERFLALEKLT-- 6210
SKE R +TIK+++K +E R L
Sbjct: 3537 TLVEQNFSRLRSKEIDRARIAEDDQKRRDTIKIVEKGNILANRRQERERRKTQEISLLRP 3596
Query: 6211 ----------TFELKETQHREEETAKRR----------------GPAHIGSPSRSTPAAE 6312
T KE + R + TA P G TP+
Sbjct: 3597 SPSGEEFSTHTMPRKERKDRAKTTADLAPGAIQIGDILASSSTVAPLQSGVEMTKTPSFN 3656
Query: 6313 TSFGAQDDGAKQGEAFE--------GTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
T + ++G +E G RK +S ++A RSW+ Y +L L F
Sbjct: 3657 TR---RTQSIRKGSRWEDMGAIDMKGFFDRKQCQQSGGKRATIRSWKNYYGILCGQLLCF 3713
Query: 6469 YKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRW 6648
+KD + E+V PP+ + G +Y K+KN L L G+E++F C E M W
Sbjct: 3714 FKDEQQFLENVAAAPPVYIYGAQCEQYPEYAKRKNSFRLLLQDGSEFIFSCPDERQMLEW 3773
Query: 6649 LTELQ 6663
+ +++
Sbjct: 3774 VAKIK 3778
Score = 422 bits (1085), Expect = e-116
Identities = 360/1685 (21%), Positives = 717/1685 (42%), Gaps = 19/1685 (1%)
Frame = +1
Query: 1165 EHERELVLKEELIRQ---EKLEQLAARFNRKAEMRET-----WLTENQRLV-SQDNFGND 1317
+ R+++ + E +R+ ++ +QL A + RE W+ E +LV S D+
Sbjct: 1320 QRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALA 1379
Query: 1318 LSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXX 1497
S++ KHEA E +I A E R +++ + + V
Sbjct: 1380 PSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDL 1439
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
+ +RL + + + +++ L S+D G L V+DLLQKHA+L
Sbjct: 1440 KKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVL 1499
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E ++ + G ++++ + ++ DG + I L +RY + A
Sbjct: 1500 EQEMGLYGNKLSDIENRGKKM----AVDGH----YDADRIHSTVGQLLQRYAAMKGPAQR 1551
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
RK L++++ Q +DV I E++ + SS D GR + +++ K + E +
Sbjct: 1552 RKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQ 1611
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
+D++ + EL S I + +E+ ++LK+L R+ + GV+ Q+
Sbjct: 1612 HGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQY 1671
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES 2397
DA +V+ ++ + ++SED G DE + LL KH + +++ + Q ++ L K
Sbjct: 1672 LFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVE 1731
Query: 2398 LPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEK 2574
L + R H + ++R D +++ L L++ R+ L DA+ LY+ ++ + I+E
Sbjct: 1732 LVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEEN 1791
Query: 2575 GKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILH 2754
++ + D E ++ ++ +FD +Q +KN + T+ A +L P + D++
Sbjct: 1792 LRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANAILRRNPPFARDVVK 1851
Query: 2755 RQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDL 2934
+Q L W L + ++ + ++L A L F D E W+ DK + L D+
Sbjct: 1852 KQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPRD--LGRDV 1909
Query: 2935 SGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERP-QEAQAIREDIKRIHQVWDIL 3111
V L + +++++ Q +L L +EA+ +++ P A+ I + + Q W+ L
Sbjct: 1910 KHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEEL 1969
Query: 3112 NKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAI 3291
+ + L A DL F + AW T + S+ L +AE L +H+ +
Sbjct: 1970 KNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRL 2029
Query: 3292 REEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
E+D ++ ++ G+++ Q ++ + L+ E L+ W R LSQ
Sbjct: 2030 SHEMDAREPEFARLVNDGEKMITAQHYASEE-IKNKTHLLKSALERLRSEWALRNGFLSQ 2088
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
+ F R+AKQ + + L + S+ E+Q KR F + DE+
Sbjct: 2089 AVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTAT 2148
Query: 3652 VGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL 3831
+ ++L + H + I N+ E R+ + LKDA +L F SD ++
Sbjct: 2149 LDHTANELMKARHMESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQI 2208
Query: 3832 REWIEEKM--IRAQDETYRDAKTITSKFVR---HQAFQSELAANKERLDQLKHAAINLGD 3996
WI+EK +R + ++ +I K R HQA ++E+ ANK +DQ+ + G+
Sbjct: 2209 EAWIDEKTNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQI----LQRGN 2264
Query: 3997 DKPEYHGT--IDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLE 4170
H I + +EL+ +W++L ++ L +A + Q + ++ W + E
Sbjct: 2265 QLKNLHRNPKIANRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKE 2324
Query: 4171 NEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAH 4350
++ D D+ + +++ ++ I Q +D + ++
Sbjct: 2325 VLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKE 2384
Query: 4351 RLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPD 4530
+ + E+ + L L R L F RDV+D I E++ K+ + G+
Sbjct: 2385 QQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFAS 2444
Query: 4531 CHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEA 4710
L + L ++ + + Q+++++ +++L +W++L +A
Sbjct: 2445 VELLVRKQSALERDMSAIHQKLIAHDKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKA 2504
Query: 4711 VKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSD 4890
+ R L S K +++L D + E W ++ M + KD + +++H +++
Sbjct: 2505 AELRNEKLNRSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAE 2564
Query: 4891 IDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXX 5070
ID ++ +R L + +E+ ++Q +++ L+
Sbjct: 2565 IDGRSEELRLLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEW 2624
Query: 5071 YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAND 5250
E QW++DKE E G + V+ML + F +T SE++
Sbjct: 2625 MLWCDEAVQCEQWLSDKETQVARGELGDTTDAVEMLIKGHSAF-EETVRKQSEKIDALTK 2683
Query: 5251 GCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSR 5430
D L+ G+ I + + LL+ M+ R +LE S+ H+F C + +
Sbjct: 2684 NADALVSGGNNYRADIVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIW 2743
Query: 5431 IMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL-RDGYAGDKA 5607
I K D+ D +++ + +KH + ++ ++++ +ER +L D + +
Sbjct: 2744 ITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSE- 2802
Query: 5608 LDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQER 5787
+ ++ E+ W LR +T RL + +L V D+ W+D+V+ E++S +
Sbjct: 2803 -QVKAQLVELRSGWDELRTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDH 2861
Query: 5788 PKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTER 5967
+D+ ELL+ +L+ EI R + + R+L + A+ + K+ ++
Sbjct: 2862 GRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARY 2921
Query: 5968 AEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKH 6147
+ + + R E L +Q+ + A WL + S E G +L+ + L KKH
Sbjct: 2922 SGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKH 2981
Query: 6148 EAFEK 6162
EK
Sbjct: 2982 ATLEK 2986
Score = 344 bits (883), Expect = 2e-92
Identities = 353/1730 (20%), Positives = 699/1730 (40%), Gaps = 39/1730 (2%)
Frame = +1
Query: 1132 INRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFG 1311
IN W +LE+ +R +R E E++A F+ E W+ + D
Sbjct: 1017 INAMWDNLERLRKQRG-------VRLEATERVAD-FDTTCESAREWMLS--KFEQLDRNP 1066
Query: 1312 NDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXX 1491
ND+ S++ + + +E I A E+ ++ ++A ERK
Sbjct: 1067 NDVKSLQNLERDLKPLEDKIAALEK--------LAAAVKKDHPEEAAAIERKIAELRALH 1118
Query: 1492 XXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDV---EDLLQ 1662
++ L +++F +++ ED+ H +DV E+LL+
Sbjct: 1119 ADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDV--HPVDVAEAEELLK 1176
Query: 1663 KHALLESDINIIGERVNNSIAQAQRF--RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
KH L I V +R RNP ++E+ L
Sbjct: 1177 KHYELGEQIKDKKYEVEYCQELGRRLLERNP-----------RMSKVEEQLQNLVSEMAS 1225
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L DL R L+ L F + ++ K E L + G + +V +LL +H++
Sbjct: 1226 LRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRD 1285
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
E L E L+ + ++ S I R ++ ++ +A RK++L
Sbjct: 1286 LEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEA 1345
Query: 2197 GVEYYQFFTDADDVDRYLYDTLR-VMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIK 2373
+EY + +AD+V ++Y+ + VMS +D + L KH+ E+ + I+
Sbjct: 1346 SLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQ 1405
Query: 2374 VLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENL---SQLRKQRLIDALSLYKLYSD 2541
++++ + L + E P++ + + Q +L+ LR ++ D L ++ D
Sbjct: 1406 QINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILED 1465
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLN 2721
A + +DE L + G D+ V+ + + LEQ+M K++++ + +++
Sbjct: 1466 A---HAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMAV 1522
Query: 2722 VEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA---HRLETFRIDCQETVTWIEDK 2892
H ++D I +L R+A ++ +++ +L+ + H+L F +DC+ + WI +K
Sbjct: 1523 DGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQL-VFDVDCE--LQWIAEK 1579
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
+ D L+ + + ++ +E ++ ++D + +A ++ + + I+
Sbjct: 1580 KPIASSQDC-GRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIK 1638
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
+ W L K +R A +D Q++L D ++W+ + +ASE+
Sbjct: 1639 AKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDE 1698
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEEL 3432
A +LL++H A+ E++ Y + +K+ + + P ++R L ++ L
Sbjct: 1699 DAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNR-PHVERFQKRQDELVREFDAL 1757
Query: 3433 QRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDF 3612
++ ++R++ L + L ++R++ + + ++ + E + + +F
Sbjct: 1758 SKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEF 1817
Query: 3613 ITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDA 3792
+ E+ + + + + A + KK + E + KL A
Sbjct: 1818 KQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVA 1877
Query: 3793 LSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLK 3972
L +F D DE +W+ +KM + RD K + S + H+A E+ ++ RL +L
Sbjct: 1878 EELHRFHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLV 1937
Query: 3973 HAAINLGDDKPEYHGTIDPQI----EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
A L K Y G QI + L +W+EL+ T+++ L A + +
Sbjct: 1938 EEAERL---KKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVR 1994
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
D+ W +++ + DL + + EM +
Sbjct: 1995 DLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQ 2054
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
E IK ++ L+RL++ R L + F R+ I + +
Sbjct: 2055 HYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLR 2114
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
+ +G S+ D K L + + + + EL+ H +
Sbjct: 2115 SLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNV 2174
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
+ L++ ++ R L ++ F D + EAW+ E+ N
Sbjct: 2175 HEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEK----------------TNG 2218
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEK----SPLTEQIQVRQAQIEKLYAG---- 5016
++K + L S+ + ++ L T H+ +E + P+ +QI R Q++ L+
Sbjct: 2219 VRKAQDLSSESISIDEKMKRLQT--HQALEAEVTANKPVVDQILQRGNQLKNLHRNPKIA 2276
Query: 5017 ------------LQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
L + ++++L WI +KEV+ + + G+D
Sbjct: 2277 NRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDM 2336
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EH ++L ER R + + + N + L+ G + + + LNE W L
Sbjct: 2337 EHCRLLLERLDG-TRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLL 2395
Query: 5341 L-ELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQN 5514
L +L R ++L A +H F D D RI EK AM DD G+D +SV L RK
Sbjct: 2396 LGQLAHYRTELLAAME-VHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSA 2454
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+D++AI +++ ++DA ++ + + + S + ++ ++W L + R +L
Sbjct: 2455 LERDMSAIHQKLIAHDKDAQKILEKRPPLRETVLDSLK-KLEESWEQLSKAAELRNEKLN 2513
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
+ L+K+++ V+ + W ++V+ +M S + PKD +G ++ H KAEID R E
Sbjct: 2514 RSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELR 2573
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
G+ L + +E+++ ++ ++ + WE LQ +LE + +A
Sbjct: 2574 LLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQ 2633
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
E WL +E + E G + LIK H AFE++ Q E+ AL K
Sbjct: 2634 CEQWLSDKETQVARGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTK 2683
Score = 256 bits (655), Expect = 4e-66
Identities = 299/1516 (19%), Positives = 609/1516 (39%), Gaps = 26/1516 (1%)
Frame = +1
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
+ +R + Y+EL LA R+R L DN +L +F+ + E E KE E L+
Sbjct: 906 VADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEVSLA------ 959
Query: 1975 DIVTVSHLLAKHKNAENNLRDLE----KYLDRLDVSGKELQDESIPGSDNIPPRLAEIRD 2142
D + H+ A + + D++ L ++ +L E S I R +I
Sbjct: 960 DEPSPEHVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQHKINA 1019
Query: 2143 YINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLK 2322
+ L+ L R RL F T + ++ + E + ++ V+
Sbjct: 1020 MWDNLERLRKQRGVRLEATERVADFDTTCESAREWM-----LSKFEQLDRNPNDVK---- 1070
Query: 2323 KHDDVHDELQNFDQHIKVLHAKAESLPQEA----REHPDIRQRLDTTLKQKAELENLSQL 2490
LQN ++ +K L K +L + A ++HP+ ++ ++ AEL L
Sbjct: 1071 -------SLQNLERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIE---RKIAELRALHAD 1120
Query: 2491 RKQRLIDALSLYKLYSDADSVES-------WIDEKGKLLATLVPGRDIEEVEIMKHRFDT 2649
+R + + L + + ES WI++ K++ V D+ E E + +
Sbjct: 1121 LLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYE 1180
Query: 2650 LEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELER 2829
L + +K+++ +V +L R+LL +P + + L + A LRD+ ++ L++
Sbjct: 1181 LGEQIKDKKYEVEYCQELGRRLLE-RNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQ 1239
Query: 2830 AHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLD 3009
L+ F + + + LE D L + + V L +R +E L A +A+L+
Sbjct: 1240 QLDLQLFNRESERIDAATKGHEAFLE-FDNLGDSVESVENLLKRHRDLEAKLDAQEARLE 1298
Query: 3010 SLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDH 3189
+ + ADD+ + + ++ I + + + + + + + + +L+ + + Q R+ D
Sbjct: 1299 AFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADE 1358
Query: 3190 FQAWLTATQRQVASEEEPQSLAEA-EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQ 3366
W+ + V S ++ A L +H A EI +++ + GD + +
Sbjct: 1359 VVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLV-SK 1417
Query: 3367 TDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYL 3546
+ + + + + W +L++ N+ L Q + + R + A L + + L
Sbjct: 1418 KHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTAL 1477
Query: 3547 AKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARN 3726
D L ++ L++H M K+ + G ++ DGHY AD+IH
Sbjct: 1478 NSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQ 1537
Query: 3727 IDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITS 3903
+ +R A + AQ L ++ Q + D D +WI E+K I + + R +
Sbjct: 1538 LLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALN 1597
Query: 3904 KFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEE 4083
+ + ++E+ + ++D++ A L I + EL T W EL+K
Sbjct: 1598 MVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRL 1657
Query: 4084 KGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIK 4263
+ + ++Q Y+ A+++ W + N + ED D + K + +M
Sbjct: 1658 RRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTT 1717
Query: 4264 KAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQF 4443
Q ++ + +E + + + + L +DRR ALE +++
Sbjct: 1718 YRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEY 1777
Query: 4444 GRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQE 4623
R+ D I E L +A ++ E LQ ++ N
Sbjct: 1778 MRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANA 1837
Query: 4624 LIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQ 4803
++ KK + LR+AW L E ++ R L +E+ H+F D E E WM+++
Sbjct: 1838 ILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADK 1897
Query: 4804 ELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE-KSPLTEQIQ 4980
M +D G+D + + HE L +I + L +A + + EQI
Sbjct: 1898 MANMPRD-LGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIG 1956
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ +E+ + L++ + + ++ DLL W S + D
Sbjct: 1957 GRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDL 2016
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
+ + LQ + + + + E NDG + +I H + I L A E L
Sbjct: 2017 QQAEWLQTEHSRLSHEMDAREPEFARLVNDG-EKMITAQHYASEEIKNKTHLLKSALERL 2075
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNY 5517
R L + H F + + ++ I K + +G + V + +++ +
Sbjct: 2076 RSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTF 2135
Query: 5518 LKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMD 5697
K ++ + E+ A ++ A EL ++ +I +S V + + LR +AR + L D
Sbjct: 2136 EKALSTLDERTATLDHTANELMKA-RHMESKNISMWQSNVHEELKLLRQDIEARHAMLKD 2194
Query: 5698 TSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVEL-------LMNNHQSLKAEIDA 5856
L F + V + W+DE + N + +D+S + + HQ+L+AE+ A
Sbjct: 2195 AFALASFDSDVAQIEAWIDE---KTNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTA 2251
Query: 5857 REENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
+ + + G L N + + +I + +L+ + ++ D+ L+ ++ +F
Sbjct: 2252 NKPVVDQILQRGNQLKNL--HRNPKIANRCDELSYKWNQLSGACADQSLALEEARDLLRF 2309
Query: 6037 ARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTF 6216
+ +W+ +E + + + G+++E L+++ + + E+ + +L
Sbjct: 2310 KQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEK 2369
Query: 6217 ELKETQHREEETAKRR 6264
+K+ + ++ K +
Sbjct: 2370 LVKQGRSSRDQVQKEQ 2385
Score = 118 bits (296), Expect = 2e-24
Identities = 154/801 (19%), Positives = 314/801 (38%), Gaps = 15/801 (1%)
Frame = +1
Query: 847 LMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKF 1026
++E+ K + + +L+ WI AK+QL + F L N +K F
Sbjct: 2723 MLEDSKKYHEFIRQCGELIIWITAKLQLAYDESF----------LDHTNLRSKLQKHMAF 2772
Query: 1027 D-EKGELEVLLFTLQ-SAMRANNQRPFVPREGKL-IADINRAWQSLEKAEHERELVLKEE 1197
D E E E L T++ + F+ + K + ++ W L + LK +
Sbjct: 2773 DSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDEL-----RTKSALKTQ 2827
Query: 1198 LIRQE-KLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIF 1374
+R+ +L L RK E E WL + + +S D+ G D+ S E KK + ++T+I
Sbjct: 2828 RLREAFELHSL----QRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIA 2883
Query: 1375 AYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQK 1554
R A ++ + ++R E + Q
Sbjct: 2884 G---RSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQA 2940
Query: 1555 IFHXXXXXXXXXXXIKSRLL---SEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIA 1725
F + R++ S + G L L +KHA LE +++ +N++
Sbjct: 2941 FFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDT-- 2998
Query: 1726 QAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWW 1905
QR G D + I + D L L + R+ L++ +++
Sbjct: 2999 -EQR-----GKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYT 3052
Query: 1906 DVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQ 2085
+ E E ++EQ + S + GRD L + + + + +DRL L
Sbjct: 3053 EETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLL 3112
Query: 2086 DESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLR 2265
+ +I + ++ L A R+ ++ +Y++F ADD+ +L + R
Sbjct: 3113 AREHHDAMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKER 3172
Query: 2266 VMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREH-PDIRQRL 2442
S+ED G+D Q ++++ + EL + + + E L + + I +
Sbjct: 3173 SASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVAAVQRAQEDLLRSGHPYGASITAKG 3232
Query: 2443 DTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATL----VPGRD 2610
+ + ++ RKQ L A +++ +AD + +W+ +K + + D
Sbjct: 3233 ADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRAD 3292
Query: 2611 IEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQL 2790
+ V+ R D MK E +V + A +L N D H + + QL
Sbjct: 3293 LASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWN---SFPDTRHHLEVRRLDMEEQL 3349
Query: 2791 RDMVDQKRNELERAHR---LETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRR 2961
+D+++ + LE+ L+++ + +E + W+++ + S+ L D++ L RR
Sbjct: 3350 KDILEAAKKHLEKLRHMQSLQSYFQEYREMMQWMKNMQSTM-TSEQLPRDVASCESLVRR 3408
Query: 2962 LSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAK 3141
++ + +D ++ + + +Q I+E + + + W +L + ++
Sbjct: 3409 HDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAEL 3468
Query: 3142 LDEAGDLQRFLRDLDHFQAWL 3204
+E D+Q++ ++ + +WL
Sbjct: 3469 YEENMDVQKWKQNAEQLDSWL 3489
Score = 112 bits (281), Expect = 1e-22
Identities = 125/686 (18%), Positives = 279/686 (40%), Gaps = 30/686 (4%)
Frame = +1
Query: 1201 IRQEKLEQLAARFN--RKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIF 1374
IR+E L A F + AE WL++ L S G+ L S + KKH +E ++
Sbjct: 2930 IRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEKELD 2989
Query: 1375 AYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQK 1554
+ + I + + + RR L+ ++ +
Sbjct: 2990 TRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHE 3049
Query: 1555 IFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQ 1734
+ +S+++G E L++ +L+ ++ + ++ +A
Sbjct: 3050 YYTEETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRAD 3109
Query: 1735 RFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVA 1914
+ D +I + L+ + +L A R+ ++ D + +F
Sbjct: 3110 GLLAREHHDAM--------SIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQAD 3161
Query: 1915 ELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES 2094
+L ++E+E+ S+ D G+D+ ++ + ++ L + + + + ++L
Sbjct: 3162 DLSDWLREKERSASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVAAVQRAQEDLLRSG 3221
Query: 2095 IPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYD---TLR 2265
P +I + A+++ + E++ RK+ L G + ++F +AD + +L D T
Sbjct: 3222 HPYGASITAKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGV 3281
Query: 2266 VMSSEDVGK-DEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQ---EAREHPDIR 2433
M ED+ + D +V+ L++HD+ ++ ++ + L +AE L + R H ++R
Sbjct: 3282 AMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWNSFPDTRHHLEVR 3341
Query: 2434 QRLDTTLKQKAELENLSQ-LRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRD 2610
RLD + K LE + L K R + +L Y + + + W+ + + RD
Sbjct: 3342 -RLDMEEQLKDILEAAKKHLEKLRHMQSLQSY--FQEYREMMQWMKNMQSTMTSEQLPRD 3398
Query: 2611 IEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQL 2790
+ E + R D +M+ ++ V + R+++ H S +I + + L WA L
Sbjct: 3399 VASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAML 3458
Query: 2791 RDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDL------------ 2934
++ + E ++ ++ + ++ +W+E++ +L D + + +
Sbjct: 3459 CEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAGLLGDDWRMVDSVEMAETHLRDFDD 3518
Query: 2935 --------SGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRI 3090
S + +RL+++E++ +++K +I+R R E R D +I
Sbjct: 3519 FLVTLEAQSEKCDMVKRLTLVEQNFSRLRSK---------EIDRARIAEDDQKRRDTIKI 3569
Query: 3091 HQVWDILNKKVREHEAKLDEAGDLQR 3168
+ +IL + +E E + + L R
Sbjct: 3570 VEKGNILANRRQERERRKTQEISLLR 3595
Score = 70.9 bits (172), Expect = 4e-10
Identities = 85/439 (19%), Positives = 173/439 (39%), Gaps = 10/439 (2%)
Frame = +1
Query: 5107 WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTD 5286
W+ +VV E+G+ V+ ++ Q + D +R C+ L + +
Sbjct: 435 WLRSVQVVLEEMEHGRSASQVEKTLKKQQAISTDIL-AREDRFKMLTAMCNELCTEKYHE 493
Query: 5287 APTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD-D 5463
+ + + + + W LL L++ R + L + L D + + A+ + D
Sbjct: 494 SDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 553
Query: 5464 LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKA--LDIGSRE-SE 5634
+G+ V L KH I A G ++++ + A + Y K D+ R+ E
Sbjct: 554 VGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSA----NNYIRHKEEQFDVLQRKLDE 609
Query: 5635 VVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVEL 5814
V + L LC +R L LF+F+ + + W+ E ++ + D+S V
Sbjct: 610 VTAQYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQ 669
Query: 5815 LMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWED 5994
+++++ E+ I+ G L+ + +I+++L ++ + +
Sbjct: 670 TTLLYKNVEMEMQTHWARSKGMIAGGERLVQNGQ-SKEDIQRRLTQMNHRWERLRVAVDA 728
Query: 5995 RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFA 6174
+L Q+ +DA AESW+ + P + S + GR+ L+++H E+ A
Sbjct: 729 LGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRA 788
Query: 6175 QEERFLALEKL------TTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDD 6336
+ LE++ + F T +ET + + P E S+ + +
Sbjct: 789 YKSDISRLEEMQSQLANSAFHTATTSQSVQETEE-----------VNVPQVEMSYNYEGN 837
Query: 6337 GAKQGEAFEGTLIRKHTYE 6393
G + + L+ K T E
Sbjct: 838 GMRVSKGEVLALLEKSTPE 856
>gi|7506776|pir||T23630 hypothetical protein R31.1 - Caenorhabditis
elegans
Length = 4101
Score = 691 bits (1782), Expect = 0.0
Identities = 531/2098 (25%), Positives = 954/2098 (45%), Gaps = 25/2098 (1%)
Frame = +1
Query: 46 DYDD-NSSARLFERSRIKALADERELVQKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKML 222
D D+ N+ FERSRI+ L DER +QKKTFTKW NS L R S ++ DL+ D+ DG ML
Sbjct: 48 DQDEFNNETLYFERSRIRTLQDERVHIQKKTFTKWCNSFLNRASLEIVDLFEDVGDGIML 107
Query: 223 LRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLG 402
++LL ++SG++L KP G+MR+ +EN+ K L FL+ + + LEN+G+ DI+D N RL LG
Sbjct: 108 MKLLEIISGDKLGKPNRGRMRVQKVENLNKVLDFLKKKKIQLENIGAEDILDRNERLILG 167
Query: 403 LIWTIILRFQIQDITFEDADNH-ETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLA 579
LIWTIILRFQI I ED + E + AK+ALLLWCQ KTAGYPNV ++NF+TSWR+GLA
Sbjct: 168 LIWTIILRFQIDTIVIEDEEERGERKHAKDALLLWCQRKTAGYPNVRIENFTTSWRNGLA 227
Query: 580 FNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSII 759
FNALIH HRPDLVD++ L + + NL AFD AE +L +A+ LDAEDV+V +PDEKSII
Sbjct: 228 FNALIHSHRPDLVDFNRLNPNEHVDNLNHAFDVAEKKLEIARLLDAEDVDVTRPDEKSII 287
Query: 760 TYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNE 939
TYV YYH+F K K + +RI ++ +LM ++ M + YE ++S+LL WI I+ L
Sbjct: 288 TYVSLYYHHFAKQKTEMTGARRIANIVGKLMVSETMEDDYEHIASELLNWIRVTIKTLES 347
Query: 940 RHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGK 1119
R F N+L G++ + +FN +RT EKPPK+ EKGELE L FT+Q+ +A +++ + P +G
Sbjct: 348 RRFPNSLNGMREEHAKFNQFRTSEKPPKYKEKGELEALFFTIQTKRKAMSRKQYQPPQGL 407
Query: 1120 LIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQ 1299
+ DI AW L+ AE+ER++ + EL RQEKLEQLA RF++KA++R++WL Q ++ +
Sbjct: 408 FMHDIESAWAQLDYAENERQVAIIAELQRQEKLEQLAQRFHKKAKLRDSWLRSVQVVLEE 467
Query: 1300 DNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVX 1479
G S VE KK +AI TDI A E+R YH+ K+ + +
Sbjct: 468 MEHGRSASQVEKTLKKQQAISTDILAREDRFKMLTAMCNELCTEKYHESDKVRGMEREII 527
Query: 1480 XXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLL 1659
R+ L + + ++ + + D+G HL+ VEDLL
Sbjct: 528 DRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRDVGKHLIGVEDLL 587
Query: 1660 QKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKEL 1839
KH LL++ IN G ++ A + +K + + + D + +Y L
Sbjct: 588 GKHDLLDAQINAHGSLLSKLSQSANNYIR--------HKEEQFDVLQRKLDEVTAQYNTL 639
Query: 1840 LDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNA 2019
++L R+ LE + L QF D E + E+E++ ++ DI V +KN
Sbjct: 640 VELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQTTLLYKNV 699
Query: 2020 ENNLRDLEKYLDRLD--VSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLA 2193
E +++ + R ++G E ++ ++I RL ++ +L+ + L+
Sbjct: 700 E---MEMQTHWARSKGMIAGGERLVQNGQSKEDIQRRLTQMNHRWERLRVAVDALGNWLS 756
Query: 2194 GGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIK 2373
Q+F DA++ + ++ + + ++ S+D+G+DEG + LL++H + +E++ + I
Sbjct: 757 EARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRAYKSDIS 816
Query: 2374 VLHAKAESLPQEAREHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSV 2553
L L A Q + Q+ E N+ Q+ Y + V
Sbjct: 817 RLEEMQSQLANSAFHTATTSQSV-----QETEEVNVPQVEMS--------YNYEGNGMRV 863
Query: 2554 ESWIDEKGKLLATLVPG-----RDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLL 2718
KG++LA L R ++ + + + + VT L
Sbjct: 864 -----SKGEVLALLEKSTPEWWRALKRDGTEGYVPANYCKIVPGETVTVTQTTQKTTTTL 918
Query: 2719 NVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTR 2898
S + RQ+K++ + +L+ + D +R L +L F +C E W ++
Sbjct: 919 EGNETKSSVVADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEV 978
Query: 2899 VLEDSDALTNDLSGVMKLQRRLSMMERDL---GAIQAKLDSLHKEADDIERERPQEAQAI 3069
L D + + V +R+ +E D+ G Q K ++ A+D+ E +++ I
Sbjct: 979 SLADEPSPEH----VAAFRRKFDKLEADMKTNGGTQLK--HINDIANDLISEGHGQSRKI 1032
Query: 3070 REDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQS 3249
+I+ +WD L + ++ +L+ + F + + W+ + Q+ + P
Sbjct: 1033 EVRQHKINAMWDNLERLRKQRGVRLEATERVADFDTTCESAREWMLSKFEQL--DRNPND 1090
Query: 3250 LAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEE 3429
+ + L + ++I + + V +D + + + +++A L+ +
Sbjct: 1091 VKSLQNLERDLKPLEDKI-------AALEKLAAAVKKDHPE-EAAAIERKIAELRALHAD 1142
Query: 3430 LQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQD 3609
L R + L Q +MF + + + + +D P + +AE LK+H +
Sbjct: 1143 LLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYE 1202
Query: 3610 FITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKD 3789
+ ++ G +L + + K+ ++ +N+ + R+ + LK
Sbjct: 1203 LGEQIKDKKYEVEYCQELGRRLL-ERNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQ 1261
Query: 3790 ALSLQQFLSDCDELREWIEEKMIRAQDETYRDA-KTITSKFVRHQAFQSELAANKERLDQ 3966
L LQ F + + + + + + D+ +++ + RH+ +++L A + RL+
Sbjct: 1262 QLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEA 1321
Query: 3967 LKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADM 4146
A ++ + I+ + ++ + + + + ++ ++L + Q + ++
Sbjct: 1322 FSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEV 1381
Query: 4147 KEWA-TQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHP 4323
W + + M+ +D + + + K E E+I I
Sbjct: 1382 VGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKH 1441
Query: 4324 DELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRD--VDDEKLWISERLVLA 4497
E N++ V Q L+ + K L ++AA Q G D ++D + E
Sbjct: 1442 YESPNVEKIVRQVNAQWGDLKKQV--WNKGLRLRQAADQKGLDRILEDAHAKLDEMQTAL 1499
Query: 4498 KAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQE 4677
+++ G L L + +L E+ + ++ I N G+++ +GH + + +
Sbjct: 1500 NSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQ 1559
Query: 4678 LRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKN 4857
L + +K + RKGDL ES HQ ++D W++E++ + G+ N
Sbjct: 1560 LLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALN 1619
Query: 4858 QIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXX 5037
+KK E+L++++++ I + +A + ++ + QI+ + +++E ++ L+
Sbjct: 1620 MVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRL 1679
Query: 5038 XXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTEN 5217
+ ++ W+ +K S++ G D + + L + + D
Sbjct: 1680 RRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTT 1739
Query: 5218 IGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHK 5397
+ + C L+ +D L ++ L +L + R LE + L++
Sbjct: 1740 Y-RQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYE 1798
Query: 5398 FYHDCRDCLSRIMEKTH-AMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDA- 5571
+ + D I E AM ++ D + L K + + + E+ E A
Sbjct: 1799 YMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAAN 1858
Query: 5572 AELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWM 5751
A LR A D+ ++ + AW L +AR S+L +L +F V + WM
Sbjct: 1859 AILRRN--PPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWM 1916
Query: 5752 DEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSE 5931
+ M ++ +DV V L +H++L EI + + L +K Y
Sbjct: 1917 ADKMANM-PRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERL--KKTYPGGN 1973
Query: 5932 IEK---KLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKE 6102
E+ + L E E+ +DR + L+ +++ F +W + S
Sbjct: 1974 AEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDL 2033
Query: 6103 YGRNLEETIKLIKKHEAFEKSAFAQEERFLAL----EKLTTFELKETQHREEETAKRR 6264
+ +L++ L +H A+E F L EK+ T QH E K +
Sbjct: 2034 HINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMIT-----AQHYASEEIKNK 2086
Score = 516 bits (1329), Expect = e-144
Identities = 380/1509 (25%), Positives = 674/1509 (44%), Gaps = 24/1509 (1%)
Frame = +1
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
I R + R++ L L + + Q++ D E E I+E+ ++ S D GR
Sbjct: 730 IQRRLTQMNHRWERLRVAVDALGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGR 789
Query: 1975 DIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINK 2154
D LL +H E +R + + RL+ +L + + A + +
Sbjct: 790 DEGAAESLLQRHARLEEEIRAYKSDISRLEEMQSQLANSAF--------HTATTSQSVQE 841
Query: 2155 LKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDD 2334
+E++ + E + Y Y + +RV E + LL K +
Sbjct: 842 TEEVNVPQVE-----MSY-----------NYEGNGMRVSKGE-------VLALLEKSTPE 878
Query: 2335 VHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQKA---------------- 2466
L+ V + +P E Q+ TTL+
Sbjct: 879 WWRALKRDGTEGYVPANYCKIVPGETVTVTQTTQKTTTTLEGNETKSSVVADRQHKISND 938
Query: 2467 --ELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHR 2640
EL+ L+ +R++ L D + L + Y + D E W E + +L E V + +
Sbjct: 939 YRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKE---IEVSLADEPSPEHVAAFRRK 995
Query: 2641 FDTLEQDMK-NQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRN 2817
FD LE DMK N ++ ++ND+A L++ H S I RQ+K+NA W L + Q+
Sbjct: 996 FDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQHKINAMWDNLERLRKQRGV 1055
Query: 2818 ELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQ 2997
LE R+ F C+ W+ K E D ND+ + L ERDL ++
Sbjct: 1056 RLEATERVADFDTTCESAREWMLSK---FEQLDRNPNDVKSLQNL-------ERDLKPLE 1105
Query: 2998 AKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLR 3177
K+ +L K A ++++ P+EA AI I + + L ++ +E ++ + F
Sbjct: 1106 DKIAALEKLAAAVKKDHPEEAAAIERKIAELRALHADLLRRAQEKMLLAEQTQGKEMFES 1165
Query: 3178 DLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVT 3357
L W+ T++ + + P +AEAE+LL +H + E+I + + + +G R+
Sbjct: 1166 ALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYELGEQIKDKKYEVEYCQELGRRLL 1225
Query: 3358 QDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQE 3537
+ +P+ + ++L L L+ ++ R +L Q L+LQ+F R++++ + E
Sbjct: 1226 E--RNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHE 1283
Query: 3538 NYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKK 3717
+L D++ S+E EN LKRH+D +DA + ++ A D + + H + I ++
Sbjct: 1284 AFLEFDNLGDSVESVENLLKRHRDLEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQR 1343
Query: 3718 ARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEK--MIRAQDETYRDAK 3891
R++ RR A R A + K+L+ +L Q+ + DE+ W+ EK ++ + D++
Sbjct: 1344 RRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPS 1403
Query: 3892 TITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEK 4071
I + ++H+AF++E+ AN+ R+ Q+ L K ++ + ++ QW +L+K
Sbjct: 1404 AIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKK 1463
Query: 4072 TTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIET 4251
KG +L A Q+ + + D +++ + +DQ DL +V +QK ++E
Sbjct: 1464 QVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQ 1523
Query: 4252 EMI---KKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALER 4422
EM K I+ D + + L ++ ++ P R+ L+
Sbjct: 1524 EMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQLL---QRYAAMKGPAQRRKGDLDE 1580
Query: 4423 KKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQ 4602
+ Q DVD E WI+E+ +A +Q+ G +L + + K + L E++ H I++
Sbjct: 1581 SRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQHGGQIDK 1640
Query: 4603 ICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEA 4782
+ ELI H+ + K EL +AW ELK+ ++ R+ + K Q+L+D E
Sbjct: 1641 VLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEV 1700
Query: 4783 EAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSP 4962
E+WM+E+ + ++ G DE + + + KH L D+ + + L K + VE P
Sbjct: 1701 ESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNRP 1760
Query: 4963 LTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQ 5142
E+ Q RQ ++ + + L Y RE DL Q I + VA S+
Sbjct: 1761 HVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSE 1820
Query: 5143 ENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLN 5322
E +DYEH++ LQ +F +F + +N GSER + + ++ A + +++L
Sbjct: 1821 EFAEDYEHLKELQSKFDEFKQKVKN-GSERFTSCETAANAILRRNPPFARDVVKKQEALR 1879
Query: 5323 EAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSR 5502
AW L E ++ R L + LH+F+ D + + +K MP DLGRD V +L +
Sbjct: 1880 TAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQ 1939
Query: 5503 KHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDART 5682
H+ K+I ++A++ +A L+ Y G A IG R+ + + W L+ D R
Sbjct: 1940 HHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRK 1999
Query: 5683 SRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDARE 5862
L DL F VRDLL W D ++ S D+ E L H L E+DARE
Sbjct: 2000 DMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDARE 2059
Query: 5863 ENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFAR 6042
F ++ G ++ +HYAS EI+ K L + + W R +L ++ + F R
Sbjct: 2060 PEFARLVNDGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQR 2119
Query: 6043 DAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFEL 6222
+A + + ++ L S G ++ + K+ + FEK+ +ER L+ T EL
Sbjct: 2120 EAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDH-TANEL 2178
Query: 6223 KETQHREEE 6249
+ +H E +
Sbjct: 2179 MKARHMESK 2187
Score = 502 bits (1292), Expect = e-140
Identities = 450/2045 (22%), Positives = 850/2045 (41%), Gaps = 107/2045 (5%)
Frame = +1
Query: 850 MENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFD 1029
+E+ + Y S+DL + I +++ F + E ++ ++F++++ + K
Sbjct: 1790 LEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVK----- 1844
Query: 1030 EKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERE--LVLKEELI 1203
E T +A+ N PF K + AW +L + R+ L + EEL
Sbjct: 1845 NGSERFTSCETAANAILRRNP-PFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEEL- 1902
Query: 1204 RQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYE 1383
RF+R + E W+ + + +D G D+ V + + HEA++ +I +
Sbjct: 1903 ---------HRFHRDVDEFEQWMADKMANMPRD-LGRDVKHVHSLWQHHEALDKEIHNSQ 1952
Query: 1384 ERXXXXXXXXXXXXXXNYHDQAK-INERKENVXXXXXXXXXXXXARRVRLELSMAIQKIF 1560
R A+ I R++ + R+ L + + F
Sbjct: 1953 PRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHT-F 2011
Query: 1561 HXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRF 1740
+ + + DL H+ D LQ+ L+++ + + ++ + R
Sbjct: 2012 NGKVRDLLAWTDLTISDIQSDL--HIND----LQQAEWLQTEHSRLSHEMDAREPEFARL 2065
Query: 1741 RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAEL 1920
N DG + I ++ +L+ + L A R L + F + ++
Sbjct: 2066 VN-DGEKMITAQHYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQI 2124
Query: 1921 EHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIP 2100
I + L S G + V + E L L++ LD + EL
Sbjct: 2125 IASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHM 2184
Query: 2101 GSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYD-TLRVMSS 2277
S NI + + + + L++ +R L F +D ++ ++ + T V +
Sbjct: 2185 ESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEKTNGVRKA 2244
Query: 2278 EDVGKDEGTVQLLLKK---HDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDT 2448
+D+ + ++ +K+ H + E+ + + + L + +P I R D
Sbjct: 2245 QDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQILQRGNQL-KNLHRNPKIANRCDE 2303
Query: 2449 TLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEI 2628
+ +L + L +A L + ++V +WI+EK L++T G+D+E +
Sbjct: 2304 LSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDMEHCRL 2363
Query: 2629 MKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQ 2808
+ R D D E + +N L +L+ + D + Q LN +W L +
Sbjct: 2364 LLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLLLGQLAH 2423
Query: 2809 KRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLG 2988
R EL A + TF D ++T I +K ++ SD D + V L R+ S +ERD+
Sbjct: 2424 YRTELLAAMEVHTFNRDVEDTDERIHEKVAAMK-SDDYGKDFASVELLVRKQSALERDMS 2482
Query: 2989 AIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQR 3168
AI KL + K+A I +RP + + + +K++ + W+ L+K KL+ + L +
Sbjct: 2483 AIHQKLIAHDKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKAAELRNEKLNRSFKLYK 2542
Query: 3169 FLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGD 3348
+L D+ + W + ++ S + P+ A ++L QH + EIDG +E+ + + G
Sbjct: 2543 YLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELRLLHEEGQ 2602
Query: 3349 RVTQDQTDPQYMFLRQRL-AGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVML 3525
+ Q+Q P++ QR +Q +L++ W++ + L + L ++ +A Q E L
Sbjct: 2603 ALNQEQ--PEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQCEQWL 2660
Query: 3526 SQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADK 3705
S +E +A+ ++ + + E +K H F T+ EKI A+ D L G+
Sbjct: 2661 SDKETQVARGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTKNADALVSGGNNYRAD 2720
Query: 3706 IHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYRD 3885
I ++ + R + ++ L+D+ +F+ C EL WI K+ A DE++ D
Sbjct: 2721 IVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIWITAKLQLAYDESFLD 2780
Query: 3886 AKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDEL 4065
+ SK +H AF SEL N++RL ++ L D + Q+ EL + WDEL
Sbjct: 2781 HTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDEL 2840
Query: 4066 EKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLI 4245
+ K Q+L +A + + D+++W ++E E++ +D D+ + + ++K +
Sbjct: 2841 RTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTL 2900
Query: 4246 ETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERK 4425
+TE+ ++ + ++ V+ + L P+ RR+ L
Sbjct: 2901 QTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDA 2960
Query: 4426 KAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQI 4605
+A FQ+ + +++ W+S+R++LA + G+SL LQK L E+D + +N
Sbjct: 2961 QAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDT 3020
Query: 4606 CNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAE 4785
G+++I + H +K + L SA LKE+ R+ L E+ AH++ + EAE
Sbjct: 3021 EQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYTEETEAE 3080
Query: 4786 AWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPL 4965
W+ EQ M E G+D+ ++ +++ L +++ F + I L +A + +
Sbjct: 3081 QWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLLAREHHD 3140
Query: 4966 TEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQE 5145
I +Q ++E L+ L + R+ DDL W+ +KE A +++
Sbjct: 3141 AMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKERSASAED 3200
Query: 5146 NGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNE 5325
GQD E Q + E+F+ R+ G ERVA + L+ GH +I +
Sbjct: 3201 YGQDLEDCQQIIEQFESTVRELAAAG-ERVAAVQRAQEDLLRSGHPYGASITAKGADVQR 3259
Query: 5326 AWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHA----MPDDLGR-DSSSVG 5490
W ++ E+ + R Q L +R +H+F + L+ + +K +DL R D +SV
Sbjct: 3260 LWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRADLASVK 3319
Query: 5491 ALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLC 5670
A ++H ++ + A+ +QVA++ +A L + + D + R ++ + + +
Sbjct: 3320 AQLQRHDEFMHGMKAVEKQVAELCHEAERLWNSFP-DTRHHLEVRRLDMEEQLKDILEAA 3378
Query: 5671 DARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEI 5850
+L L + R+++ WM ++ M S++ P+DV+ E L+ H E+
Sbjct: 3379 KKHLEKLRHMQSLQSYFQEYREMMQWMKNMQSTMTSEQLPRDVASCESLVRRHDEYNLEM 3438
Query: 5851 DAREENFNACISLGRDLLNRKHYASSEIEKK----------LIKLTTERAEM------MR 5982
R+ + GR ++ H S EI++K L ++ +RAE+ ++
Sbjct: 3439 QGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAELYEENMDVQ 3498
Query: 5983 RWEDRWEYLQLILEV--------YQFARDAAVAESWLFAQEPYLI--------------- 6093
+W+ E L LE ++ +AE+ L + +L+
Sbjct: 3499 KWKQNAEQLDSWLEERAGLLGDDWRMVDSVEMAETHLRDFDDFLVTLEAQSEKCDMVKRL 3558
Query: 6094 -----------SKEYGR--------NLEETIKLIKKHEAFEKSAFAQEERFLALEKLT-- 6210
SKE R +TIK+++K +E R L
Sbjct: 3559 TLVEQNFSRLRSKEIDRARIAEDDQKRRDTIKIVEKGNILANRRQERERRKTQEISLLRP 3618
Query: 6211 ----------TFELKETQHREEETAKRR----------------GPAHIGSPSRSTPAAE 6312
T KE + R + TA P G TP+
Sbjct: 3619 SPSGEEFSTHTMPRKERKDRAKTTADLAPGAIQIGDILASSSTVAPLQSGVEMTKTPSFN 3678
Query: 6313 TSFGAQDDGAKQGEAFE--------GTLIRKHTYESLDRKAANRSWEKLYAVLRQNELSF 6468
T + ++G +E G RK +S ++A RSW+ Y +L L F
Sbjct: 3679 TR---RTQSIRKGSRWEDMGAIDMKGFFDRKQCQQSGGKRATIRSWKNYYGILCGQLLCF 3735
Query: 6469 YKDPKHRDESVHGEPPMALPGCSVNVASDYQKKKNVLSLRLPIGAEYLFQCGSEEDMQRW 6648
+KD + E+V PP+ + G +Y K+KN L L G+E++F C E M W
Sbjct: 3736 FKDEQQFLENVAAAPPVYIYGAQCEQYPEYAKRKNSFRLLLQDGSEFIFSCPDERQMLEW 3795
Query: 6649 LTELQ 6663
+ +++
Sbjct: 3796 VAKIK 3800
Score = 422 bits (1085), Expect = e-116
Identities = 360/1685 (21%), Positives = 717/1685 (42%), Gaps = 19/1685 (1%)
Frame = +1
Query: 1165 EHERELVLKEELIRQ---EKLEQLAARFNRKAEMRET-----WLTENQRLV-SQDNFGND 1317
+ R+++ + E +R+ ++ +QL A + RE W+ E +LV S D+
Sbjct: 1342 QRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADEVVGWMYEKAKLVMSGDDSALA 1401
Query: 1318 LSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXX 1497
S++ KHEA E +I A E R +++ + + V
Sbjct: 1402 PSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDL 1461
Query: 1498 XXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALL 1677
+ +RL + + + +++ L S+D G L V+DLLQKHA+L
Sbjct: 1462 KKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVL 1521
Query: 1678 ESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAE 1857
E ++ + G ++++ + ++ DG + I L +RY + A
Sbjct: 1522 EQEMGLYGNKLSDIENRGKKM----AVDGH----YDADRIHSTVGQLLQRYAAMKGPAQR 1573
Query: 1858 RKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRD 2037
RK L++++ Q +DV I E++ + SS D GR + +++ K + E +
Sbjct: 1574 RKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALNMVKKQEQLEAEVNQ 1633
Query: 2038 LEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQF 2217
+D++ + EL S I + +E+ ++LK+L R+ + GV+ Q+
Sbjct: 1634 HGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRLRRAVVDWGVKEQQY 1693
Query: 2218 FTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAES 2397
DA +V+ ++ + ++SED G DE + LL KH + +++ + Q ++ L K
Sbjct: 1694 LFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTTYRQWLEKLEVKCVE 1753
Query: 2398 LPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEK 2574
L + R H + ++R D +++ L L++ R+ L DA+ LY+ ++ + I+E
Sbjct: 1754 LVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEYMRESADLGQSIEEN 1813
Query: 2575 GKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILH 2754
++ + D E ++ ++ +FD +Q +KN + T+ A +L P + D++
Sbjct: 1814 LRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANAILRRNPPFARDVVK 1873
Query: 2755 RQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDL 2934
+Q L W L + ++ + ++L A L F D E W+ DK + L D+
Sbjct: 1874 KQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADKMANMPRD--LGRDV 1931
Query: 2935 SGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERP-QEAQAIREDIKRIHQVWDIL 3111
V L + +++++ Q +L L +EA+ +++ P A+ I + + Q W+ L
Sbjct: 1932 KHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIGGRQQTLEQEWEEL 1991
Query: 3112 NKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAI 3291
+ + L A DL F + AW T + S+ L +AE L +H+ +
Sbjct: 1992 KNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRL 2051
Query: 3292 REEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
E+D ++ ++ G+++ Q ++ + L+ E L+ W R LSQ
Sbjct: 2052 SHEMDAREPEFARLVNDGEKMITAQHYASEE-IKNKTHLLKSALERLRSEWALRNGFLSQ 2110
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
+ F R+AKQ + + L + S+ E+Q KR F + DE+
Sbjct: 2111 AVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTFEKALSTLDERTAT 2170
Query: 3652 VGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL 3831
+ ++L + H + I N+ E R+ + LKDA +L F SD ++
Sbjct: 2171 LDHTANELMKARHMESKNISMWQSNVHEELKLLRQDIEARHAMLKDAFALASFDSDVAQI 2230
Query: 3832 REWIEEKM--IRAQDETYRDAKTITSKFVR---HQAFQSELAANKERLDQLKHAAINLGD 3996
WI+EK +R + ++ +I K R HQA ++E+ ANK +DQ+ + G+
Sbjct: 2231 EAWIDEKTNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTANKPVVDQI----LQRGN 2286
Query: 3997 DKPEYHGT--IDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLE 4170
H I + +EL+ +W++L ++ L +A + Q + ++ W + E
Sbjct: 2287 QLKNLHRNPKIANRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKE 2346
Query: 4171 NEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAH 4350
++ D D+ + +++ ++ I Q +D + ++
Sbjct: 2347 VLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKE 2406
Query: 4351 RLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPD 4530
+ + E+ + L L R L F RDV+D I E++ K+ + G+
Sbjct: 2407 QQHLNEKWRLLLGQLAHYRTELLAAMEVHTFNRDVEDTDERIHEKVAAMKSDDYGKDFAS 2466
Query: 4531 CHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEA 4710
L + L ++ + + Q+++++ +++L +W++L +A
Sbjct: 2467 VELLVRKQSALERDMSAIHQKLIAHDKDAQKILEKRPPLRETVLDSLKKLEESWEQLSKA 2526
Query: 4711 VKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSD 4890
+ R L S K +++L D + E W ++ M + KD + +++H +++
Sbjct: 2527 AELRNEKLNRSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAE 2586
Query: 4891 IDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXX 5070
ID ++ +R L + +E+ ++Q +++ L+
Sbjct: 2587 IDGRSEELRLLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEW 2646
Query: 5071 YALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAND 5250
E QW++DKE E G + V+ML + F +T SE++
Sbjct: 2647 MLWCDEAVQCEQWLSDKETQVARGELGDTTDAVEMLIKGHSAF-EETVRKQSEKIDALTK 2705
Query: 5251 GCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSR 5430
D L+ G+ I + + LL+ M+ R +LE S+ H+F C + +
Sbjct: 2706 NADALVSGGNNYRADIVTRSEEVTARHALLLKSMEKRGHMLEDSKKYHEFIRQCGELIIW 2765
Query: 5431 IMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL-RDGYAGDKA 5607
I K D+ D +++ + +KH + ++ ++++ +ER +L D + +
Sbjct: 2766 ITAKLQLAYDESFLDHTNLRSKLQKHMAFDSELVENEKRLSTVERQGEQLVTDNHFMSE- 2824
Query: 5608 LDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQER 5787
+ ++ E+ W LR +T RL + +L V D+ W+D+V+ E++S +
Sbjct: 2825 -QVKAQLVELRSGWDELRTKSALKTQRLREAFELHSLQRKVEDIEKWLDKVEGELSSDDH 2883
Query: 5788 PKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTER 5967
+D+ ELL+ +L+ EI R + + R+L + A+ + K+ ++
Sbjct: 2884 GRDILSTELLIKKLDTLQTEIAGRSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARY 2943
Query: 5968 AEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKH 6147
+ + + R E L +Q+ + A WL + S E G +L+ + L KKH
Sbjct: 2944 SGLDEPVQIRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKH 3003
Query: 6148 EAFEK 6162
EK
Sbjct: 3004 ATLEK 3008
Score = 344 bits (883), Expect = 2e-92
Identities = 353/1730 (20%), Positives = 699/1730 (40%), Gaps = 39/1730 (2%)
Frame = +1
Query: 1132 INRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFG 1311
IN W +LE+ +R +R E E++A F+ E W+ + D
Sbjct: 1039 INAMWDNLERLRKQRG-------VRLEATERVAD-FDTTCESAREWMLS--KFEQLDRNP 1088
Query: 1312 NDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXX 1491
ND+ S++ + + +E I A E+ ++ ++A ERK
Sbjct: 1089 NDVKSLQNLERDLKPLEDKIAALEK--------LAAAVKKDHPEEAAAIERKIAELRALH 1140
Query: 1492 XXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDV---EDLLQ 1662
++ L +++F +++ ED+ H +DV E+LL+
Sbjct: 1141 ADLLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDV--HPVDVAEAEELLK 1198
Query: 1663 KHALLESDINIIGERVNNSIAQAQRF--RNPDGPDGSGYKPVEPGTIDERSDVLQKRYKE 1836
KH L I V +R RNP ++E+ L
Sbjct: 1199 KHYELGEQIKDKKYEVEYCQELGRRLLERNP-----------RMSKVEEQLQNLVSEMAS 1247
Query: 1837 LLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKN 2016
L DL R L+ L F + ++ K E L + G + +V +LL +H++
Sbjct: 1248 LRDLYRRRDTILKQQLDLQLFNRESERIDAATKGHEAFLEFDNLGDSVESVENLLKRHRD 1307
Query: 2017 AENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAG 2196
E L E L+ + ++ S I R ++ ++ +A RK++L
Sbjct: 1308 LEAKLDAQEARLEAFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEA 1367
Query: 2197 GVEYYQFFTDADDVDRYLYDTLR-VMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIK 2373
+EY + +AD+V ++Y+ + VMS +D + L KH+ E+ + I+
Sbjct: 1368 SLEYQEMRREADEVVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQ 1427
Query: 2374 VLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENL---SQLRKQRLIDALSLYKLYSD 2541
++++ + L + E P++ + + Q +L+ LR ++ D L ++ D
Sbjct: 1428 QINSEGDGLVSKKHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILED 1487
Query: 2542 ADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLN 2721
A + +DE L + G D+ V+ + + LEQ+M K++++ + +++
Sbjct: 1488 A---HAKLDEMQTALNSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMAV 1544
Query: 2722 VEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERA---HRLETFRIDCQETVTWIEDK 2892
H ++D I +L R+A ++ +++ +L+ + H+L F +DC+ + WI +K
Sbjct: 1545 DGHYDADRIHSTVGQLLQRYAAMKGPAQRRKGDLDESRLWHQL-VFDVDCE--LQWIAEK 1601
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
+ D L+ + + ++ +E ++ ++D + +A ++ + + I+
Sbjct: 1602 KPIASSQDC-GRTLTEALNMVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIK 1660
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
+ W L K +R A +D Q++L D ++W+ + +ASE+
Sbjct: 1661 AKSSELETAWSELKKLLRLRRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDE 1720
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEEL 3432
A +LL++H A+ E++ Y + +K+ + + P ++R L ++ L
Sbjct: 1721 DAARKLLSKHRALCEDMTTYRQWLEKLEVKCVELVESNR-PHVERFQKRQDELVREFDAL 1779
Query: 3433 QRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDF 3612
++ ++R++ L + L ++R++ + + ++ + E + + +F
Sbjct: 1780 SKLAEDRRNALEDAVCLYEYMRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEF 1839
Query: 3613 ITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDA 3792
+ E+ + + + + A + KK + E + KL A
Sbjct: 1840 KQKVKNGSERFTSCETAANAILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVA 1899
Query: 3793 LSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLK 3972
L +F D DE +W+ +KM + RD K + S + H+A E+ ++ RL +L
Sbjct: 1900 EELHRFHRDVDEFEQWMADKMANMPRDLGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLV 1959
Query: 3973 HAAINLGDDKPEYHGTIDPQI----EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIA 4140
A L K Y G QI + L +W+EL+ T+++ L A + +
Sbjct: 1960 EEAERL---KKTYPGGNAEQIGGRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVR 2016
Query: 4141 DMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXH 4320
D+ W +++ + DL + + EM +
Sbjct: 2017 DLLAWTDLTISDIQSDLHINDLQQAEWLQTEHSRLSHEMDAREPEFARLVNDGEKMITAQ 2076
Query: 4321 PDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAK 4500
E IK ++ L+RL++ R L + F R+ I + +
Sbjct: 2077 HYASEEIKNKTHLLKSALERLRSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLR 2136
Query: 4501 AQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQEL 4680
+ +G S+ D K L + + + + EL+ H +
Sbjct: 2137 SLAVGGSVADVESQTKRLDTFEKALSTLDERTATLDHTANELMKARHMESKNISMWQSNV 2196
Query: 4681 RSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQ 4860
+ L++ ++ R L ++ F D + EAW+ E+ N
Sbjct: 2197 HEELKLLRQDIEARHAMLKDAFALASFDSDVAQIEAWIDEK----------------TNG 2240
Query: 4861 IKKHERLQSDIDKFADTIRALATKAHKFVEEK----SPLTEQIQVRQAQIEKLYAG---- 5016
++K + L S+ + ++ L T H+ +E + P+ +QI R Q++ L+
Sbjct: 2241 VRKAQDLSSESISIDEKMKRLQT--HQALEAEVTANKPVVDQILQRGNQLKNLHRNPKIA 2298
Query: 5017 ------------LQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
L + ++++L WI +KEV+ + + G+D
Sbjct: 2299 NRCDELSYKWNQLSGACADQSLALEEARDLLRFKQLVENVLAWINEKEVLVSTADMGKDM 2358
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
EH ++L ER R + + + N + L+ G + + + LNE W L
Sbjct: 2359 EHCRLLLERLDG-TRSDSIVDEQTLDEINRLGEKLVKQGRSSRDQVQKEQQHLNEKWRLL 2417
Query: 5341 L-ELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQN 5514
L +L R ++L A +H F D D RI EK AM DD G+D +SV L RK
Sbjct: 2418 LGQLAHYRTELLAAME-VHTFNRDVEDTDERIHEKVAAMKSDDYGKDFASVELLVRKQSA 2476
Query: 5515 YLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLM 5694
+D++AI +++ ++DA ++ + + + S + ++ ++W L + R +L
Sbjct: 2477 LERDMSAIHQKLIAHDKDAQKILEKRPPLRETVLDSLK-KLEESWEQLSKAAELRNEKLN 2535
Query: 5695 DTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFN 5874
+ L+K+++ V+ + W ++V+ +M S + PKD +G ++ H KAEID R E
Sbjct: 2536 RSFKLYKYLDDVKKVEQWANQVRNKMTSHQTPKDSNGARKILEQHHERKAEIDGRSEELR 2595
Query: 5875 ACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAV 6054
G+ L + +E+++ ++ ++ + WE LQ +LE + +A
Sbjct: 2596 LLHEEGQALNQEQPEHKAEVQRAHKRVQNSEHQLRQTWESEKGTLQKLLEWMLWCDEAVQ 2655
Query: 6055 AESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEK 6204
E WL +E + E G + LIK H AFE++ Q E+ AL K
Sbjct: 2656 CEQWLSDKETQVARGELGDTTDAVEMLIKGHSAFEETVRKQSEKIDALTK 2705
Score = 256 bits (655), Expect = 4e-66
Identities = 299/1516 (19%), Positives = 609/1516 (39%), Gaps = 26/1516 (1%)
Frame = +1
Query: 1795 IDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGR 1974
+ +R + Y+EL LA R+R L DN +L +F+ + E E KE E L+
Sbjct: 928 VADRQHKISNDYRELKRLADVRRRLLSDNIKLLRFYRECDEFERWAKEIEVSLA------ 981
Query: 1975 DIVTVSHLLAKHKNAENNLRDLE----KYLDRLDVSGKELQDESIPGSDNIPPRLAEIRD 2142
D + H+ A + + D++ L ++ +L E S I R +I
Sbjct: 982 DEPSPEHVAAFRRKFDKLEADMKTNGGTQLKHINDIANDLISEGHGQSRKIEVRQHKINA 1041
Query: 2143 YINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLK 2322
+ L+ L R RL F T + ++ + E + ++ V+
Sbjct: 1042 MWDNLERLRKQRGVRLEATERVADFDTTCESAREWM-----LSKFEQLDRNPNDVK---- 1092
Query: 2323 KHDDVHDELQNFDQHIKVLHAKAESLPQEA----REHPDIRQRLDTTLKQKAELENLSQL 2490
LQN ++ +K L K +L + A ++HP+ ++ ++ AEL L
Sbjct: 1093 -------SLQNLERDLKPLEDKIAALEKLAAAVKKDHPEEAAAIE---RKIAELRALHAD 1142
Query: 2491 RKQRLIDALSLYKLYSDADSVES-------WIDEKGKLLATLVPGRDIEEVEIMKHRFDT 2649
+R + + L + + ES WI++ K++ V D+ E E + +
Sbjct: 1143 LLRRAQEKMLLAEQTQGKEMFESALRDMIGWIEKTRKVMMEDVHPVDVAEAEELLKKHYE 1202
Query: 2650 LEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELER 2829
L + +K+++ +V +L R+LL +P + + L + A LRD+ ++ L++
Sbjct: 1203 LGEQIKDKKYEVEYCQELGRRLLE-RNPRMSKVEEQLQNLVSEMASLRDLYRRRDTILKQ 1261
Query: 2830 AHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLD 3009
L+ F + + + LE D L + + V L +R +E L A +A+L+
Sbjct: 1262 QLDLQLFNRESERIDAATKGHEAFLE-FDNLGDSVESVENLLKRHRDLEAKLDAQEARLE 1320
Query: 3010 SLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDH 3189
+ + ADD+ + + ++ I + + + + + + + + +L+ + + Q R+ D
Sbjct: 1321 AFSRTADDMIKAQHADSAYIEQRRRDVLARREAVRRAAAQRKKQLEASLEYQEMRREADE 1380
Query: 3190 FQAWLTATQRQVASEEEPQSLAEA-EQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQ 3366
W+ + V S ++ A L +H A EI +++ + GD + +
Sbjct: 1381 VVGWMYEKAKLVMSGDDSALAPSAIPHRLLKHEAFEAEIIANEPRIQQINSEGDGLV-SK 1439
Query: 3367 TDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYL 3546
+ + + + + W +L++ N+ L Q + + R + A L + + L
Sbjct: 1440 KHYESPNVEKIVRQVNAQWGDLKKQVWNKGLRLRQAADQKGLDRILEDAHAKLDEMQTAL 1499
Query: 3547 AKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARN 3726
D L ++ L++H M K+ + G ++ DGHY AD+IH
Sbjct: 1500 NSKDQGLDLRSVKDLLQKHAVLEQEMGLYGNKLSDIENRGKKMAVDGHYDADRIHSTVGQ 1559
Query: 3727 IDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWI-EEKMIRAQDETYRDAKTITS 3903
+ +R A + AQ L ++ Q + D D +WI E+K I + + R +
Sbjct: 1560 LLQRYAAMKGPAQRRKGDLDESRLWHQLVFDVDCELQWIAEKKPIASSQDCGRTLTEALN 1619
Query: 3904 KFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEE 4083
+ + ++E+ + ++D++ A L I + EL T W EL+K
Sbjct: 1620 MVKKQEQLEAEVNQHGGQIDKVLLQAGELIKRHHSASSQIKAKSSELETAWSELKKLLRL 1679
Query: 4084 KGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIK 4263
+ + ++Q Y+ A+++ W + N + ED D + K + +M
Sbjct: 1680 RRAVVDWGVKEQQYLFDAAEVESWMNEKRNALASEDYGNDEDAARKLLSKHRALCEDMTT 1739
Query: 4264 KAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQF 4443
Q ++ + +E + + + + L +DRR ALE +++
Sbjct: 1740 YRQWLEKLEVKCVELVESNRPHVERFQKRQDELVREFDALSKLAEDRRNALEDAVCLYEY 1799
Query: 4444 GRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQE 4623
R+ D I E L +A ++ E LQ ++ N
Sbjct: 1800 MRESADLGQSIEENLRVAMSEEFAEDYEHLKELQSKFDEFKQKVKNGSERFTSCETAANA 1859
Query: 4624 LIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQ 4803
++ KK + LR+AW L E ++ R L +E+ H+F D E E WM+++
Sbjct: 1860 ILRRNPPFARDVVKKQEALRTAWNTLCEYIEARDSKLAVAEELHRFHRDVDEFEQWMADK 1919
Query: 4804 ELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEE-KSPLTEQIQ 4980
M +D G+D + + HE L +I + L +A + + EQI
Sbjct: 1920 MANMPRD-LGRDVKHVHSLWQHHEALDKEIHNSQPRLAKLVEEAERLKKTYPGGNAEQIG 1978
Query: 4981 VRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDY 5160
RQ +E+ + L++ + + ++ DLL W S + D
Sbjct: 1979 GRQQTLEQEWEELKNATDDRKDMLRAAFDLHTFNGKVRDLLAWTDLTISDIQSDLHINDL 2038
Query: 5161 EHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENL 5340
+ + LQ + + + + E NDG + +I H + I L A E L
Sbjct: 2039 QQAEWLQTEHSRLSHEMDAREPEFARLVNDG-EKMITAQHYASEEIKNKTHLLKSALERL 2097
Query: 5341 LELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNY 5517
R L + H F + + ++ I K + +G + V + +++ +
Sbjct: 2098 RSEWALRNGFLSQAVQWHAFQREAKQIIASIGSKRTTLRSLAVGGSVADVESQTKRLDTF 2157
Query: 5518 LKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMD 5697
K ++ + E+ A ++ A EL ++ +I +S V + + LR +AR + L D
Sbjct: 2158 EKALSTLDERTATLDHTANELMKA-RHMESKNISMWQSNVHEELKLLRQDIEARHAMLKD 2216
Query: 5698 TSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVEL-------LMNNHQSLKAEIDA 5856
L F + V + W+DE + N + +D+S + + HQ+L+AE+ A
Sbjct: 2217 AFALASFDSDVAQIEAWIDE---KTNGVRKAQDLSSESISIDEKMKRLQTHQALEAEVTA 2273
Query: 5857 REENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
+ + + G L N + + +I + +L+ + ++ D+ L+ ++ +F
Sbjct: 2274 NKPVVDQILQRGNQLKNL--HRNPKIANRCDELSYKWNQLSGACADQSLALEEARDLLRF 2331
Query: 6037 ARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTF 6216
+ +W+ +E + + + G+++E L+++ + + E+ + +L
Sbjct: 2332 KQLVENVLAWINEKEVLVSTADMGKDMEHCRLLLERLDGTRSDSIVDEQTLDEINRLGEK 2391
Query: 6217 ELKETQHREEETAKRR 6264
+K+ + ++ K +
Sbjct: 2392 LVKQGRSSRDQVQKEQ 2407
Score = 118 bits (296), Expect = 2e-24
Identities = 154/801 (19%), Positives = 314/801 (38%), Gaps = 15/801 (1%)
Frame = +1
Query: 847 LMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKF 1026
++E+ K + + +L+ WI AK+QL + F L N +K F
Sbjct: 2745 MLEDSKKYHEFIRQCGELIIWITAKLQLAYDESF----------LDHTNLRSKLQKHMAF 2794
Query: 1027 D-EKGELEVLLFTLQ-SAMRANNQRPFVPREGKL-IADINRAWQSLEKAEHERELVLKEE 1197
D E E E L T++ + F+ + K + ++ W L + LK +
Sbjct: 2795 DSELVENEKRLSTVERQGEQLVTDNHFMSEQVKAQLVELRSGWDEL-----RTKSALKTQ 2849
Query: 1198 LIRQE-KLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIF 1374
+R+ +L L RK E E WL + + +S D+ G D+ S E KK + ++T+I
Sbjct: 2850 RLREAFELHSL----QRKVEDIEKWLDKVEGELSSDDHGRDILSTELLIKKLDTLQTEIA 2905
Query: 1375 AYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQK 1554
R A ++ + ++R E + Q
Sbjct: 2906 G---RSDAVVEMMKKARELRVQGSAAADDCLKQAEQVEARYSGLDEPVQIRRENLVDAQA 2962
Query: 1555 IFHXXXXXXXXXXXIKSRLL---SEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIA 1725
F + R++ S + G L L +KHA LE +++ +N++
Sbjct: 2963 FFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEKELDTRQSAMNDT-- 3020
Query: 1726 QAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWW 1905
QR G D + I + D L L + R+ L++ +++
Sbjct: 3021 -EQR-----GKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHEYYT 3074
Query: 1906 DVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQ 2085
+ E E ++EQ + S + GRD L + + + + +DRL L
Sbjct: 3075 EETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRADGLL 3134
Query: 2086 DESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLR 2265
+ +I + ++ L A R+ ++ +Y++F ADD+ +L + R
Sbjct: 3135 AREHHDAMSIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQADDLSDWLREKER 3194
Query: 2266 VMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREH-PDIRQRL 2442
S+ED G+D Q ++++ + EL + + + E L + + I +
Sbjct: 3195 SASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVAAVQRAQEDLLRSGHPYGASITAKG 3254
Query: 2443 DTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATL----VPGRD 2610
+ + ++ RKQ L A +++ +AD + +W+ +K + + D
Sbjct: 3255 ADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGVAMEQEDLSRAD 3314
Query: 2611 IEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQL 2790
+ V+ R D MK E +V + A +L N D H + + QL
Sbjct: 3315 LASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWN---SFPDTRHHLEVRRLDMEEQL 3371
Query: 2791 RDMVDQKRNELERAHR---LETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRR 2961
+D+++ + LE+ L+++ + +E + W+++ + S+ L D++ L RR
Sbjct: 3372 KDILEAAKKHLEKLRHMQSLQSYFQEYREMMQWMKNMQSTM-TSEQLPRDVASCESLVRR 3430
Query: 2962 LSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAK 3141
++ + +D ++ + + +Q I+E + + + W +L + ++
Sbjct: 3431 HDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAMLCEIWKDRAEL 3490
Query: 3142 LDEAGDLQRFLRDLDHFQAWL 3204
+E D+Q++ ++ + +WL
Sbjct: 3491 YEENMDVQKWKQNAEQLDSWL 3511
Score = 112 bits (281), Expect = 1e-22
Identities = 125/686 (18%), Positives = 279/686 (40%), Gaps = 30/686 (4%)
Frame = +1
Query: 1201 IRQEKLEQLAARFN--RKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIF 1374
IR+E L A F + AE WL++ L S G+ L S + KKH +E ++
Sbjct: 2952 IRRENLVDAQAFFQWVKAAEEDLEWLSDRMMLASSGESGDSLQSALSLQKKHATLEKELD 3011
Query: 1375 AYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQK 1554
+ + I + + + RR L+ ++ +
Sbjct: 3012 TRQSAMNDTEQRGKDMIRQRHFASTHIQKILDRLSSAMLTLKESCGLRRDLLQEAIDAHE 3071
Query: 1555 IFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQ 1734
+ +S+++G E L++ +L+ ++ + ++ +A
Sbjct: 3072 YYTEETEAEQWLREQMPLAMSQEMGRDQAGAESHLRRLTVLDKEVELFKNEIDRLKKRAD 3131
Query: 1735 RFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVA 1914
+ D +I + L+ + +L A R+ ++ D + +F
Sbjct: 3132 GLLAREHHDAM--------SIAAKQRKLEALFGDLCRECARRRTQIVDASKYHKFVRQAD 3183
Query: 1915 ELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDES 2094
+L ++E+E+ S+ D G+D+ ++ + ++ L + + + + ++L
Sbjct: 3184 DLSDWLREKERSASAEDYGQDLEDCQQIIEQFESTVRELAAAGERVAAVQRAQEDLLRSG 3243
Query: 2095 IPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYD---TLR 2265
P +I + A+++ + E++ RK+ L G + ++F +AD + +L D T
Sbjct: 3244 HPYGASITAKGADVQRLWTHVNEVANERKQALNGARQVHRFDQEADQILNWLQDKEATGV 3303
Query: 2266 VMSSEDVGK-DEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQ---EAREHPDIR 2433
M ED+ + D +V+ L++HD+ ++ ++ + L +AE L + R H ++R
Sbjct: 3304 AMEQEDLSRADLASVKAQLQRHDEFMHGMKAVEKQVAELCHEAERLWNSFPDTRHHLEVR 3363
Query: 2434 QRLDTTLKQKAELENLSQ-LRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRD 2610
RLD + K LE + L K R + +L Y + + + W+ + + RD
Sbjct: 3364 -RLDMEEQLKDILEAAKKHLEKLRHMQSLQSY--FQEYREMMQWMKNMQSTMTSEQLPRD 3420
Query: 2611 IEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQL 2790
+ E + R D +M+ ++ V + R+++ H S +I + + L WA L
Sbjct: 3421 VASCESLVRRHDEYNLEMQGRKPFVDDFARQGRRMIQSSHVLSQEIQEKVDILEKSWAML 3480
Query: 2791 RDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDL------------ 2934
++ + E ++ ++ + ++ +W+E++ +L D + + +
Sbjct: 3481 CEIWKDRAELYEENMDVQKWKQNAEQLDSWLEERAGLLGDDWRMVDSVEMAETHLRDFDD 3540
Query: 2935 --------SGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRI 3090
S + +RL+++E++ +++K +I+R R E R D +I
Sbjct: 3541 FLVTLEAQSEKCDMVKRLTLVEQNFSRLRSK---------EIDRARIAEDDQKRRDTIKI 3591
Query: 3091 HQVWDILNKKVREHEAKLDEAGDLQR 3168
+ +IL + +E E + + L R
Sbjct: 3592 VEKGNILANRRQERERRKTQEISLLR 3617
Score = 70.9 bits (172), Expect = 4e-10
Identities = 85/439 (19%), Positives = 173/439 (39%), Gaps = 10/439 (2%)
Frame = +1
Query: 5107 WIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTD 5286
W+ +VV E+G+ V+ ++ Q + D +R C+ L + +
Sbjct: 457 WLRSVQVVLEEMEHGRSASQVEKTLKKQQAISTDIL-AREDRFKMLTAMCNELCTEKYHE 515
Query: 5287 APTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPD-D 5463
+ + + + + W LL L++ R + L + L D + + A+ + D
Sbjct: 516 SDKVRGMEREIIDRWTQLLTLLEQRKRALMSLNDLMSLLRDIDTLSNELYSLEPAVRNRD 575
Query: 5464 LGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKA--LDIGSRE-SE 5634
+G+ V L KH I A G ++++ + A + Y K D+ R+ E
Sbjct: 576 VGKHLIGVEDLLGKHDLLDAQINAHGSLLSKLSQSA----NNYIRHKEEQFDVLQRKLDE 631
Query: 5635 VVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVEL 5814
V + L LC +R L LF+F+ + + W+ E ++ + D+S V
Sbjct: 632 VTAQYNTLVELCRSRRLGLERARSLFQFVQDHEEEMAWLAEKEKLCTTALNSGDISAVPQ 691
Query: 5815 LMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWED 5994
+++++ E+ I+ G L+ + +I+++L ++ + +
Sbjct: 692 TTLLYKNVEMEMQTHWARSKGMIAGGERLVQNGQ-SKEDIQRRLTQMNHRWERLRVAVDA 750
Query: 5995 RWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFA 6174
+L Q+ +DA AESW+ + P + S + GR+ L+++H E+ A
Sbjct: 751 LGNWLSEARHAQQYFQDANEAESWIREKMPLVKSDDLGRDEGAAESLLQRHARLEEEIRA 810
Query: 6175 QEERFLALEKL------TTFELKETQHREEETAKRRGPAHIGSPSRSTPAAETSFGAQDD 6336
+ LE++ + F T +ET + + P E S+ + +
Sbjct: 811 YKSDISRLEEMQSQLANSAFHTATTSQSVQETEE-----------VNVPQVEMSYNYEGN 859
Query: 6337 GAKQGEAFEGTLIRKHTYE 6393
G + + L+ K T E
Sbjct: 860 GMRVSKGEVLALLEKSTPE 878
>gi|47477769|gb|AAH70885.1| Spna2 protein [Rattus norvegicus]
Length = 2452
Score = 660 bits (1702), Expect = 0.0
Identities = 437/1506 (29%), Positives = 735/1506 (48%), Gaps = 119/1506 (7%)
Frame = +1
Query: 2104 SDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSED 2283
+++I R ++ D ++ KELS R+++L + F DA+++++++ + L+V S E+
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDEN 71
Query: 2284 VGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQ 2460
KD +Q L+KH E+Q I L + E + IR RL +Q
Sbjct: 72 Y-KDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQ 130
Query: 2461 KAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHR 2640
L + + +L+ A L + + + V WI++K ++ + G+D+E VE+++ +
Sbjct: 131 WELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKK 190
Query: 2641 FDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNE 2820
F+ + D+ E +V VN A +L+ +HP + I +Q ++NA W +L+ + Q++ +
Sbjct: 191 FEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLALQRQGK 250
Query: 2821 LERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQA 3000
L A ++ F D ET+ WI++K +++ SD DL+ V L R+ +ERDL A++
Sbjct: 251 LFGAAEVQRFNRDVDETIGWIKEKEQLMA-SDDFGRDLASVQALLRKHEGLERDLAALED 309
Query: 3001 KLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRD 3180
K+ +L EAD +++ P A I+ + + W+ + E A+LD++ LQRFL D
Sbjct: 310 KVKALCAEADRLQQSHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLAD 369
Query: 3181 LDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRV-- 3354
+W+T + + ++E +A AE LL++H + EID + + +K G +
Sbjct: 370 FRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLA 429
Query: 3355 ----TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVM 3522
D+ +R++L+ L E L +W+ R+ Q ++LQ+F RD +Q +
Sbjct: 430 AGHYASDE-------VREKLSILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNW 482
Query: 3523 LSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAAD 3702
+S+QE +L +D+ SL+ E LK+H+DF ++ A +EKI A+ F +L Q+ HYA +
Sbjct: 483 MSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAME 542
Query: 3703 KIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYR 3882
+ + + RR A E+A +L D+ LQQF D DEL+ W+ EKM A DE Y+
Sbjct: 543 DVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYK 602
Query: 3883 DAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDE 4062
D + K +HQAF++EL+AN+ R+D L+ A L D + ++ E+ + W +
Sbjct: 603 DPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKK 662
Query: 4063 LEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHL 4242
L + TE KG KL +AN+QQ + +++ D++ W ++E + +D DLT V +K L
Sbjct: 663 LLEATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHAL 722
Query: 4243 IETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALER 4422
+E ++ ID + ENIK + A+ + + L+ P+ R++ L
Sbjct: 723 LEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLAD 782
Query: 4423 KKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQ 4602
Q RDV+DE+ WI E+ +A + N G+ L L K Q L EI HEP I
Sbjct: 783 SLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKA 842
Query: 4603 ICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEA 4782
+ G +++EGH + K+ EL W+ LK R+ DL +S +A Q+ D EA
Sbjct: 843 VTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEA 902
Query: 4783 ------------------------------EAWMSE-------------------QELYM 4815
EA MS+ Q++
Sbjct: 903 ESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAP 962
Query: 4816 MQDERGKD------EFSTKNQ----IKKHERLQ--------------SDIDKFADTIRAL 4923
M DE GK+ ++ K+ +KK + L +D F
Sbjct: 963 MDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVK 1022
Query: 4924 ATKAHKFVEEKSPLTEQ--IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDD 5097
+ ++ L EQ I +RQ QI+ Y L + + L RE ++
Sbjct: 1023 KLDPAQSASRENLLEEQGSIALRQGQIDNQYQSLLELGEKRKGMLEKSCKKFMLFREANE 1082
Query: 5098 LLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHG 5277
L QWI +KE S+E G D E V++LQ++F F +D + R+ + N + L G
Sbjct: 1083 LQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLK-ANESRLKDINKVAEDLESEG 1141
Query: 5278 ---------------------HTDAPTIALWKDS---------------LNEAWENLLEL 5349
D+ T + WK + LNE W +L +L
Sbjct: 1142 LMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQL 1201
Query: 5350 MDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKD 5526
+ R+Q+L ++ + +F+ D + I EK A+ D+ G D +SV AL RKH+ + +D
Sbjct: 1202 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 1261
Query: 5527 IAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSD 5706
+AA+G++V + A L + + A D+ + +E+ +AW L D R ++L D+ D
Sbjct: 1262 LAALGDKVNSLGETAQRLIQSHP-ESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHD 1320
Query: 5707 LFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACIS 5886
L +F++ RDL+ W++ ++ ++S E KDV+G E L+ HQ + EIDAR F A
Sbjct: 1321 LQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQ 1380
Query: 5887 LGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESW 6066
G+ LL HYAS EI++KL L ER ++ + W R L LE+ F RD AE+W
Sbjct: 1381 FGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENW 1440
Query: 6067 LFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREE 6246
+ A+E +L +++ G +L+ LIKKHE F+K+ QEE+ AL+ + + +
Sbjct: 1441 MAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKG 1500
Query: 6247 ETAKRR 6264
+ A RR
Sbjct: 1501 DIANRR 1506
Score = 526 bits (1356), Expect = e-147
Identities = 384/1551 (24%), Positives = 692/1551 (43%), Gaps = 126/1551 (8%)
Frame = +1
Query: 1123 IADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQD 1302
+A A S A HER + + +L L+Q F R ++ ++W+ E + + +
Sbjct: 544 VATRRDALLSRRNALHERAMHRRAQLADSFHLQQ----FFRDSDELKSWVNEKMKTATDE 599
Query: 1303 NFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXX 1482
+ D S+++ +KH+A E ++ A + R N++ + ++ R V
Sbjct: 600 AY-KDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVIS 658
Query: 1483 XXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQ 1662
+ V+L + Q+ ++ L S+D G L +V++L +
Sbjct: 659 LWKKLLEATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQK 718
Query: 1663 KHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELL 1842
KHALLE+D+ +R++ QA++F++ D K ++ + L RY+ L
Sbjct: 719 KHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIK--------KKQEALVARYEALK 770
Query: 1843 DLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAE 2022
+ RK++L D+ RL Q + DV + E I+E+E + +ST+ G+D++ V +LL KH+ +
Sbjct: 771 EPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQ 830
Query: 2023 NNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASR-------- 2178
+ E + + G + +E ++++ +L+E+ LK ++ R
Sbjct: 831 AEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSL 890
Query: 2179 ------------------KERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGT 2304
KE + G +Y + D D + L +MS D+ +
Sbjct: 891 QAQQYFADANEAESWMREKEPIVGSTDYGK---DEDSAEALLKKHEALMS--DLSAYGSS 945
Query: 2305 VQLLLKKHDDVHDELQNFDQH-----IKVLHAKAESLPQEAR-EHPDIRQRLDTTLK--- 2457
+Q L ++ ++ D + L+ E P+E + DI L++T K
Sbjct: 946 IQALREQAQSCRQQVAPMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWW 1005
Query: 2458 ----------------------QKAELENL------------------------SQLRKQ 2499
Q A ENL + RK
Sbjct: 1006 KVEVNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQIDNQYQSLLELGEKRKG 1065
Query: 2500 RLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEA 2679
L + + L+ +A+ ++ WI+EK L + G D+E+VE+++ +FD ++D+K E+
Sbjct: 1066 MLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANES 1125
Query: 2680 KVTNVNDLARQLLN----------VEHPNSDDILHRQN---------------------- 2763
++ ++N +A L + V+ ++ R
Sbjct: 1126 RLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKSARLMVHTVATF 1185
Query: 2764 ----KLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTND 2931
+LN RW L+ + +++ L AH ++ F D ET WIE+K + L ++D +D
Sbjct: 1186 NSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQAL-NTDNYGHD 1244
Query: 2932 LSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDIL 3111
L+ V LQR+ ERDL A+ K++SL + A + + P+ A+ ++E ++Q W L
Sbjct: 1245 LASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSL 1304
Query: 3112 NKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAI 3291
K+ + +AKL ++ DLQRFL D +W+ + V+S+E + + AE LL +H
Sbjct: 1305 GKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEH 1364
Query: 3292 REEIDGYAEDYKKMRAMGDRVTQD--QTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLL 3465
R EID A ++ G ++ P+ ++++L L + +L++ W R+ +L
Sbjct: 1365 RTEIDARAGTFQAFEQFGQQLLAHGHYASPE---IKEKLDILDQERTDLEKAWVQRRMML 1421
Query: 3466 SQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKI 3645
L LQ+F RD +QAE ++ +E +L +D SL+ E +K+H+DF ++ +EKI
Sbjct: 1422 DHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKI 1481
Query: 3646 RAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCD 3825
A+ F DQL HYA I + + +R + + E KL ++ +LQQF D D
Sbjct: 1482 AALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVD 1541
Query: 3826 ELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKP 4005
E+ WI EK+ A DE+Y+D I SK +HQAF++EL AN +R+ I++G+
Sbjct: 1542 EIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRI----RGVIDMGNSLI 1597
Query: 4006 E------YHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQL 4167
E + ++ LA QW L + + EK QKL +AN+QQ + I D W +++
Sbjct: 1598 ERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEV 1657
Query: 4168 ENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKA 4347
E + ED DL +VN ++K L+E ++ + + +K
Sbjct: 1658 EALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKE 1717
Query: 4348 HRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLP 4527
R + + Q++++ RR L QF RD+DDE+ WI E+ +L +++ G L
Sbjct: 1718 KRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLT 1777
Query: 4528 DCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKE 4707
L+K + L E+ HEP I + + G++L D+ ++++ + W+ELK+
Sbjct: 1778 GVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQ 1837
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
R L ES + QF+ + E EAW++E+ + ++ G + + +KKHE ++
Sbjct: 1838 LAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFET 1897
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXX 5067
D D + + T +++ + E I + + + L+
Sbjct: 1898 DFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENSA 1957
Query: 5068 XYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAN 5247
+ + D + WI +KE + + G+D VQ L + + F + E +AN
Sbjct: 1958 FLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANIT 2017
Query: 5248 DGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTR-AQILEASRLLHK 5397
D L+ H + I SL + W LL TR ++LEA K
Sbjct: 2018 ALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRK 2068
Score = 444 bits (1142), Expect = e-122
Identities = 383/1838 (20%), Positives = 785/1838 (41%), Gaps = 51/1838 (2%)
Frame = +1
Query: 820 KRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFEN--NLEGV--QRQLTE 987
K + + + +E+ ++ + +L +WI K+Q+ ++ ++++ NL+G + Q E
Sbjct: 30 KELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQVASDENYKDPTNLQGKLQKHQAFE 89
Query: 988 FNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAE 1167
K DE G L + S + +++R W+ L +
Sbjct: 90 AEVQANSGAIVKLDETGNLMISEGHFASETIRTR-----------LMELHRQWELLLEKM 138
Query: 1168 HERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKK 1347
E+ + +L++ +KL Q + R+ E W+ + + +V+ + G DL VE KK
Sbjct: 139 REKGI----KLLQAQKLVQ----YLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKK 190
Query: 1348 HEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVR 1527
E +TD+ A+EER + ++ I ++E V R+ +
Sbjct: 191 FEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAWQRLKGLALQRQGK 250
Query: 1528 LELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGER 1707
L + +Q+ + + S+D G L V+ LL+KH LE D+ + ++
Sbjct: 251 LFGAAEVQRFNRDVDETIGWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDK 310
Query: 1708 VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKR 1887
V A+A R + P+ I + + L ++++ LAAER RL+D+ R
Sbjct: 311 VKALCAEADRLQQS--------HPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYR 362
Query: 1888 LCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDV 2067
L +F D +L + E + ++++ + D+ LL +H+ + + E D
Sbjct: 363 LQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADE 422
Query: 2068 SGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRY 2247
SG+ L SD + +L+ + + L EL R+++ ++ F+ D + VD +
Sbjct: 423 SGQALLAAGHYASDEVREKLSILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNW 482
Query: 2248 LYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHP 2424
+ + +ED+G +V+ LLKKH+D L ++ I L A L Q
Sbjct: 483 MSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAME 542
Query: 2425 DIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPG 2604
D+ R D L ++ L + R+ +L D+ L + + D+D ++SW++EK K AT
Sbjct: 543 DVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMK-TATDEAY 601
Query: 2605 RDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWA 2784
+D ++ + E ++ ++++ + ++L++V H +++ R N++ + W
Sbjct: 602 KDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWK 661
Query: 2785 QLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRL 2964
+L + + K +L A++ + F + ++ W+ + L SD DL+ V LQ++
Sbjct: 662 KLLEATELKGVKLREANQQQQFNRNVEDIELWLYEVEGHLA-SDDYGKDLTNVQNLQKKH 720
Query: 2965 SMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKL 3144
+++E D+ A Q ++D + +A + +A+ I++ + + ++ L + + + KL
Sbjct: 721 ALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKL 780
Query: 3145 DEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDY 3324
++ LQ+ RD++ + W+ + AS + L + LL +H A++ EI G+
Sbjct: 781 ADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRI 840
Query: 3325 KKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDA 3504
K + G+ + ++ ++ +L+ L + WE L+ R+ L L Q + DA
Sbjct: 841 KAVTQKGNAMVEEGHFAA-EDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADA 899
Query: 3505 KQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQD 3684
+AE + ++E + D + + AE LK+H+ ++ + A I+A+
Sbjct: 900 NEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQAL---------- 949
Query: 3685 GHYAADKIHKKARNIDERRGAN--------REKA-QEVLKKLKDALSLQQFLSDCDELRE 3837
A ++ +D+ G +EK+ +EV K D L+L + ++
Sbjct: 950 -REQAQSCRQQVAPMDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTN-----KD 1003
Query: 3838 WIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHG 4017
W + ++ Q FV AA ++LD + A+ ++ E G
Sbjct: 1004 WWKVEVNDRQG------------FVP--------AAYVKKLDPAQSAS---RENLLEEQG 1040
Query: 4018 TIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQP 4197
+I + ++ Q+ L + E++ L + ++ + + ++++W + E +T E+
Sbjct: 1041 SIALRQGQIDNQYQSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVG 1100
Query: 4198 GDLTTVNVAMQK---------------------------QHLI--ETEMIKKAQHIDXXX 4290
DL V V +K + L+ E + +++ +
Sbjct: 1101 ADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMP 1160
Query: 4291 XXXXXXXXXHPDELENIKAHRLA-------VQEQLQRLQAPLDDRRKALERKKAAFQFGR 4449
P + + H +A + E+ + LQ ++R + L +F R
Sbjct: 1161 RDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHR 1220
Query: 4450 DVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELI 4629
D D+ K WI E+ N G L LQ+ + ++ +N + Q LI
Sbjct: 1221 DADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLI 1280
Query: 4630 DEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQEL 4809
+ ++K EL AW L + RK LG+S +FL D + +W++
Sbjct: 1281 QSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRG 1340
Query: 4810 YMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQ 4989
+ DE KD + +++H+ +++ID A T +A + + + +I+ +
Sbjct: 1341 LVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKL 1400
Query: 4990 AQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHV 5169
+++ L+ HR+ + W+A +E +++ G + V
Sbjct: 1401 DILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSV 1460
Query: 5170 QMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLEL 5349
+ L ++ + F + N+ E++A D LI H IA ++ + + W L
Sbjct: 1461 EALIKKHEDFDK-AINVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQ 1519
Query: 5350 MDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDI 5529
M + L S+ L +F D + + I EK D+ +D +++ + +KHQ + ++
Sbjct: 1520 MIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAEL 1579
Query: 5530 AAIGEQV-AQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSD 5706
A +++ I+ + + G + +R + + W+ L ++ +L + +
Sbjct: 1580 HANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANK 1639
Query: 5707 LFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACIS 5886
F ++D W+ EV+ + S++ KD++ V L+ HQ L+A+I A E+ S
Sbjct: 1640 QQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNS 1699
Query: 5887 LGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESW 6066
L+ + +S++++K + ++ R L ++QF RD ESW
Sbjct: 1700 QADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESW 1759
Query: 6067 LFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQE 6180
+ ++ + S++YGR+L L KKH+ E A E
Sbjct: 1760 IKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHE 1797
Score = 439 bits (1130), Expect = e-121
Identities = 413/1946 (21%), Positives = 813/1946 (41%), Gaps = 61/1946 (3%)
Frame = +1
Query: 610 DLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYF 789
DL + LQK Q+ E ++ A+ + P+E+ I T +
Sbjct: 180 DLEHVEVLQKK--FEEFQTDLAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQEEVNAAW 237
Query: 790 NKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGV 969
+LK +Q R GK+ + R+ + + WI K QL+ F +L V
Sbjct: 238 QRLKGLALQ--RQGKLFGAAE-----VQRFNRDVDETIGWIKEKEQLMASDDFGRDLASV 290
Query: 970 QRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQ 1149
Q L + LE L L+ ++A L A+ +R Q
Sbjct: 291 QALLRKHEG---------------LERDLAALEDKVKA------------LCAEADRLQQ 323
Query: 1150 SLEKAEHERELVLKEELIRQEKLEQLAARFNRK-----------AEMRE--TWLTENQRL 1290
S + ++ ++ +E + E++ LAA + + A+ R+ +W+TE + L
Sbjct: 324 SHPLSANQIQVKREELITNWEQIRTLAAERHARLDDSYRLQRFLADFRDLTSWVTEMKAL 383
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
++ D ND++ EA +H+ + +I A+E+ ++ ++ E+
Sbjct: 384 INADELANDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLS 443
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+ RR + E M +Q + ++ LL+EDLG L VE
Sbjct: 444 ILSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVE 503
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
LL+KH E ++ E++ A + + Y + T R D L R
Sbjct: 504 ALLKKHEDFEKSLSAQEEKITALDEFATKLIQ-----NNHYAMEDVAT---RRDALLSRR 555
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKH 2010
L + A R+ +L D+ L QF+ D EL+ + E+ + ++ + +D + + KH
Sbjct: 556 NALHERAMHRRAQLADSFHLQQFFRDSDELKSWVNEKMKT-ATDEAYKDPSNLQGKVQKH 614
Query: 2011 KNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERL 2190
+ E L + +D L+ +G++L D + + + R+ E+ KL E + + +L
Sbjct: 615 QAFEAELSANQSRIDALEKAGQKLIDVNHYAKEEVAARMNEVISLWKKLLEATELKGVKL 674
Query: 2191 AGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHI 2370
+ QF + +D++ +LY+ ++S+D GKD VQ L KKH + ++ I
Sbjct: 675 REANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRI 734
Query: 2371 KVLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDAD 2547
+ +A + +I+++ + + + L+ RKQ+L D+L L +L+ D +
Sbjct: 735 DGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVE 794
Query: 2548 SVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE 2727
E+WI EK + A+ G+D+ V+ + + L+ ++ E ++ V ++
Sbjct: 795 DEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG 854
Query: 2728 HPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
H ++D+ + ++LN +W L+ Q+R +LE + + + + D E +W+ +K ++
Sbjct: 855 HFAAEDVKAKLSELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVG 914
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERE-RPQEAQAIREDIK 3084
+D ++ S L++ ++M DL A + + +L ++A ++ P + + +E +
Sbjct: 915 STDYGKDEDSAEALLKKHEALMS-DLSAYGSSIQALREQAQSCRQQVAPMDDETGKELVL 973
Query: 3085 RIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQ------VASEEEPQ 3246
++ D K RE K GD+ L + + RQ + +P
Sbjct: 974 ALY---DYQEKSPREVTMK---KGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPA 1027
Query: 3247 SLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWE 3426
A E LL + +I + Q Q D QY +
Sbjct: 1028 QSASRENLLEEQGSIA-------------------LRQGQIDNQY--------------Q 1054
Query: 3427 ELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQ 3606
L + + R+ +L + M R+A + + ++++E L +++ LEQ E K+
Sbjct: 1055 SLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFD 1114
Query: 3607 DFITTMDANDEKIRAVGMFGDQLCQDGHYAAD---------------------------- 3702
DF + AN+ +++ + + L +G A +
Sbjct: 1115 DFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDEADSKTASPWKS 1174
Query: 3703 ---KIHKKA-----RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMI 3858
+H A + ++ER + ++ A+E + L A +Q+F D DE +EWIEEK
Sbjct: 1175 ARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQ 1234
Query: 3859 RAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQI 4035
+ Y D ++ + +H+ F+ +LAA ++++ L A L PE + +
Sbjct: 1235 ALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKC 1294
Query: 4036 EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTV 4215
EL W L K +++ KL D++ Q ++ D+ W + ++ ++ D+T
Sbjct: 1295 TELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGA 1354
Query: 4216 NVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPL 4395
+++ TE+ +A IK + ++ L+
Sbjct: 1355 EALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAW 1414
Query: 4396 DDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEI 4575
RR L+ F RD + + W++ R ++ G+SL L K + I
Sbjct: 1415 VQRRMMLDHCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAI 1474
Query: 4576 DNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAH 4755
+ E I + +LI H + E+ W+ LK + +++ LGES+
Sbjct: 1475 NVQEEKIAALQAFADQLIAVDHYAKGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQ 1534
Query: 4756 QFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKA 4935
QF D E EAW+SE+ L DE KD + +++ +KH+ ++++ AD IR +
Sbjct: 1535 QFSRDVDEIEAWISEK-LQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMG 1593
Query: 4936 HKFVEEKSPLTEQ--IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQW 5109
+ +E + + ++ R A + + L + I D W
Sbjct: 1594 NSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFW 1653
Query: 5110 IADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDA 5289
+++ E + S++ G+D V L ++ Q D + +R+ + N D+L+ D
Sbjct: 1654 LSEVEALLASEDYGKDLASVNNLLKKHQLLEADI-SAHEDRLKDLNSQADSLMTSSAFDT 1712
Query: 5290 PTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAMP-DDL 5466
+ +D++N ++ + + +R L S LH+F+ D D S I EK + +D
Sbjct: 1713 SQVKEKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDY 1772
Query: 5467 GRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKA 5646
GRD + V L +KH+ ++AA + + +L D + +I R ++ V+
Sbjct: 1773 GRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQE-EIQQRLAQFVEH 1831
Query: 5647 WRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNN 5826
W+ L+ L AR RL ++ + +F+ V + W++E + S++ ++ ++ L+
Sbjct: 1832 WKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKK 1891
Query: 5827 HQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEY 6006
H++ + + ++ N + G+DL+ + ++ I K+ L + +++ + R
Sbjct: 1892 HEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAK 1951
Query: 6007 LQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEER 6186
L QF A V ESW+ +E L + +YGR+L L+ K E F+ A ++
Sbjct: 1952 LDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQE 2011
Query: 6187 FLALEKLTTFELKETQHREEETAKRR 6264
+A +L +H + + + R
Sbjct: 2012 GIANITALKDQLLAAKHIQSKAIEAR 2037
Score = 387 bits (993), Expect = e-105
Identities = 384/1845 (20%), Positives = 767/1845 (40%), Gaps = 59/1845 (3%)
Frame = +1
Query: 850 MENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFD 1029
+++ + R+ DL W+ L+N N++ G + L ++
Sbjct: 357 LDDSYRLQRFLADFRDLTSWVTEMKALINADELANDVAGAEALLDRHQEH---------- 406
Query: 1030 EKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQ 1209
KGE++ + +SA + + G +D R + L ER +L+ +R+
Sbjct: 407 -KGEIDAHEDSFKSADESGQA---LLAAGHYASDEVR--EKLSILSEERAALLELWELRR 460
Query: 1210 EKLEQLA--ARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYE 1383
++ EQ F R E + W+++ + + ++ G+ L SVEA KKHE E + A E
Sbjct: 461 QQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQE 520
Query: 1384 ERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFH 1563
E+ N++ + R++ + RR +L S +Q+ F
Sbjct: 521 EKITALDEFATKLIQNNHYAMEDVATRRDALLSRRNALHERAMHRRAQLADSFHLQQFFR 580
Query: 1564 XXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFR 1743
K + +++ +++ +QKH E++++ R++ Q+
Sbjct: 581 DSDELKSWVNE-KMKTATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLI 639
Query: 1744 NPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELE 1923
D + Y E + R + + +K+LL+ + +L + + QF +V ++E
Sbjct: 640 -----DVNHYAKEE---VAARMNEVISLWKKLLEATELKGVKLREANQQQQFNRNVEDIE 691
Query: 1924 HGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPG 2103
+ E E L+S D G+D+ V +L KH E ++ + +D + + ++ QD
Sbjct: 692 LWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFD 751
Query: 2104 SDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSED 2283
++NI + + LKE +RK++LA + Q F D +D + ++ + + +S +
Sbjct: 752 AENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTN 811
Query: 2284 VGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHPDIRQRLDTTLKQ 2460
GKD VQ LLKKH + E+ + IK + K ++ +E D++ +L ++
Sbjct: 812 RGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLSELNQK 871
Query: 2461 KAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHR 2640
L+ + R+Q L D+L + ++DA+ ESW+ EK ++ + G+D + E + +
Sbjct: 872 WEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKK 931
Query: 2641 FDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSD-------------------------- 2742
+ L D+ + + + + A+ P D
Sbjct: 932 HEALMSDLSAYGSSIQALREQAQSCRQQVAPMDDETGKELVLALYDYQEKSPREVTMKKG 991
Query: 2743 DILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDAL 2922
DIL N N W ++ V+ ++ + A+ + +E++ + +
Sbjct: 992 DILTLLNSTNKDWWKVE--VNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQGQI 1049
Query: 2923 TNDLSGVMKL-QRRLSMMERDLGAIQAKLDSLHKEADDI-----ERERPQEAQAIREDIK 3084
N +++L ++R M+E+ K L +EA+++ E+E ++ + D++
Sbjct: 1050 DNQYQSLLELGEKRKGMLEKS-----CKKFMLFREANELQQWINEKEAALTSEEVGADLE 1104
Query: 3085 RIHQV---WDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLA 3255
++ + +D K ++ +E++L D+ + DL+ L A + Q ++E +
Sbjct: 1105 QVEVLQKKFDDFQKDLKANESRLK---DINKVAEDLE--SEGLMAEEVQAVQQQEVYGMM 1159
Query: 3256 EAEQLLNQHAAIREEIDGY-AEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEEL 3432
R+E D A +K R M V + + L E W L
Sbjct: 1160 P-----------RDEADSKTASPWKSARLMVHTVATFNS----------IKELNERWRSL 1198
Query: 3433 QRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDF 3612
Q++ + R LL +Q F RDA + + + ++ L D+ L + ++H+ F
Sbjct: 1199 QQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGF 1258
Query: 3613 ITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDA 3792
+ A +K+ ++G +L Q +A+ + +K +++ + ++A + KL D+
Sbjct: 1259 ERDLAALGDKVNSLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDS 1318
Query: 3793 LSLQQFLSDCDELREWIEE-KMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQL 3969
LQ+FLSD +L WI + + + DE +D + RHQ ++E+ A
Sbjct: 1319 HDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAF 1378
Query: 3970 KHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMK 4149
+ L I +++ L + +LEK ++ L QL+ + +
Sbjct: 1379 EQFGQQLLAHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAE 1438
Query: 4150 EWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDE 4329
W E + ED+ L +V ++K + + + + I
Sbjct: 1439 NWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYA 1498
Query: 4330 LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQN 4509
+I R V ++ +RL+A + ++R L + QF RDVD+ + WISE+L A ++
Sbjct: 1499 KGDIANRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDES 1558
Query: 4510 LGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGP--AFEKKIQELR 4683
+ + QK+ Q E+ + I + + G LI+ G G A + ++ L
Sbjct: 1559 YKDPTNIQSKHQKH-QAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALA 1617
Query: 4684 SAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQI 4863
WQ L + ++ L E+ K F + + W+SE E + ++ GKD S N +
Sbjct: 1618 DQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLL 1677
Query: 4864 KKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXX 5043
KKH+ L++DI D ++ L ++A + + T Q++ ++ I + ++
Sbjct: 1678 KKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKEKRDTINGRFQKIKSMATSRR 1737
Query: 5044 XXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIG 5223
+ R++DD WI +K+++ S++ G+D VQ L+++ ++ +
Sbjct: 1738 AKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELA-AH 1796
Query: 5224 SERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFY 5403
+ D L I E W+ L +L R Q LE S +F
Sbjct: 1797 EPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFV 1856
Query: 5404 HDCRDCLSRIMEK-THAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL 5580
+ + + I EK T +D G +++ L +KH+ + D ++V + + +L
Sbjct: 1857 ANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDL 1916
Query: 5581 ------RDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLL 5742
+ K + + S++ KA A+ +D + F N D++
Sbjct: 1917 IKKNNHHEENISSKMKGLNGKVSDLEKA--------AAQRKAKLDENSAFLQFNWKADVV 1968
Query: 5743 -LWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRD-LLNRKH 5916
W+ E + + + + +D+S V+ L+ ++ A + A ++ A I+ +D LL KH
Sbjct: 1969 ESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKH 2028
Query: 5917 YASSEIE-------KKLIKLTTERAEMMRRWEDRWEYLQLILEVY-QFARDAAVAESWLF 6072
S IE K+ +L A ++ + + + + +++ FA+ A+ SW
Sbjct: 2029 IQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFE 2088
Query: 6073 AQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 6207
E L +LEE L + H+AF S + + F L +L
Sbjct: 2089 NAEEDLTDPVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAEL 2133
Score = 277 bits (708), Expect = 3e-72
Identities = 251/1159 (21%), Positives = 503/1159 (42%), Gaps = 63/1159 (5%)
Frame = +1
Query: 1600 KSRLLSEDLGAHLMDVEDLLQKHALLESD----------INIIGERVNNSIAQAQRFRNP 1749
++ L SE++GA L VE L +K + D IN + E + + A+ +
Sbjct: 1091 EAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAV 1150
Query: 1750 DGPDGSGYKPVEPGTIDERSD------------------VLQKRYKELLDLAAERKRRLE 1875
+ G P + S L +R++ L LA ER + L
Sbjct: 1151 QQQEVYGMMPRDEADSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLG 1210
Query: 1876 DNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLD 2055
+ +F D E + I+E+ Q L++ + G D+ +V L KH+ E +L L ++
Sbjct: 1211 SAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVN 1270
Query: 2056 RLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADD 2235
L + + L ++++ + E+ L + + RK +L + +F +D D
Sbjct: 1271 SLGETAQRLIQSHPESAEDLKEKCTELNQAWTSLGKRADQRKAKLGDSHDLQRFLSDFRD 1330
Query: 2236 VDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR 2415
+ ++ ++SS+++ KD + LL++H + E+ D A E Q+
Sbjct: 1331 LMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEI---DARAGTFQA-FEQFGQQLL 1386
Query: 2416 EH-----PDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGK 2580
H P+I+++LD +++ +LE R+ L L L + D + E+W+ +
Sbjct: 1387 AHGHYASPEIKEKLDILDQERTDLEKAWVQRRMMLDHCLELQLFHRDCEQAENWMAAREA 1446
Query: 2581 LLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQ 2760
L T G ++ VE + + + ++ + QE K+ + A QL+ V+H DI +R+
Sbjct: 1447 FLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAVDHYAKGDIANRR 1506
Query: 2761 NKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSG 2940
N++ RW +L+ + +KR++L + L+ F D E WI +K + SD D +
Sbjct: 1507 NEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTA--SDESYKDPTN 1564
Query: 2941 VMKLQRRLSMMERDLGAIQAKLDSLHKEADD-IERERPQEAQ-AIREDIKRIHQVWDILN 3114
+ ++ E +L A ++ + + IER ++ A++ + + W L
Sbjct: 1565 IQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLV 1624
Query: 3115 KKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIR 3294
+K E KL EA Q F + F WL+ + +ASE+ + LA LL +H +
Sbjct: 1625 QKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLE 1684
Query: 3295 EEIDGYAEDYKKMRAMGDRV-TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQ 3471
+I + + K + + D + T D + +++ + +++++ M +R+ LS+
Sbjct: 1685 ADISAHEDRLKDLNSQADSLMTSSAFDTSQV--KEKRDTINGRFQKIKSMATSRRAKLSE 1742
Query: 3472 GLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRA 3651
L F RD E + +++ ++ +D + L +N K+H+ + A++ I+
Sbjct: 1743 SHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQG 1802
Query: 3652 VGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDEL 3831
V G +L D ++I ++ E ++ A ++L+++L QQF+++ +E
Sbjct: 1803 VLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEE 1862
Query: 3832 REWIEEKMIRAQDETYRDA-KTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPE 4008
WI EKM E Y D I +H+AF+++ +K+R++ + +L
Sbjct: 1863 EAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNH 1922
Query: 4009 YHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKE-WATQLENEMTR 4185
+ I +++ L + +LEK ++ KL D N L AD+ E W + EN +
Sbjct: 1923 HEENISSKMKGLNGKVSDLEKAAAQRKAKL-DENSAFLQFNWKADVVESWIGEKENSLKT 1981
Query: 4186 EDQPGDLTTVNVAMQKQHLIETEMIKKAQH-IDXXXXXXXXXXXXHPDELENIKAHRLAV 4362
+D DL++V + KQ + + Q I + + I+A ++
Sbjct: 1982 DDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHIQSKAIEARHASL 2041
Query: 4363 QEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKA--QNLGESLPD-- 4530
++ +L A R+K L ++ F R V+D L +++ + +N E L D
Sbjct: 2042 MKRWTQLLANSATRKKKLLEAQSHF---RKVEDLFLTFAKKASAFNSWFENAEEDLTDPV 2098
Query: 4531 -CHRLQKNLQL------LSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSA 4689
C+ L++ L + + + + NQ+ +++ A+ P ++ L
Sbjct: 2099 RCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEET 2158
Query: 4690 WQELKEAVKDRKGDLGESEK--------AHQFLYDCGEAEAWMSEQELYM-----MQDER 4830
W+ L++ +K+R+ +L + ++ +F W+ E Y+ M +E
Sbjct: 2159 WRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEES 2218
Query: 4831 GKDEFSTKNQIKKHERLQS 4887
G E + +KH+ +++
Sbjct: 2219 GTLESQLEATKRKHQEIRA 2237
Score = 222 bits (565), Expect = 1e-55
Identities = 206/908 (22%), Positives = 383/908 (41%), Gaps = 25/908 (2%)
Frame = +1
Query: 907 WINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRAN 1086
W+ A+ LN ++L+ V+ + + D+ +K E+ + F Q +
Sbjct: 1440 WMAAREAFLNTEDKGDSLDSVEALIKKHEDF---DKAINVQEEKIAALQAFADQLIAVDH 1496
Query: 1087 NQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRET 1266
+ + + D W+ L+ E+ L E Q +F+R + E
Sbjct: 1497 YAKGDIANRRNEVLD---RWRRLKAQMIEKRSKLGES--------QTLQQFSRDVDEIEA 1545
Query: 1267 WLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNY--H 1440
W++E + S +++ D +++++ +KH+A E ++ A +R
Sbjct: 1546 WISEKLQTASDESY-KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAG 1604
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
+ + R + + +L+ + Q +++ L SE
Sbjct: 1605 SEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASE 1664
Query: 1621 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 1800
D G L V +LL+KH LLE+DI+ +R+ + +QA D S K
Sbjct: 1665 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVK-------- 1716
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
E+ D + R++++ +A R+ +L ++ RL QF+ D+ + E IKE++ ++SS D GRD+
Sbjct: 1717 EKRDTINGRFQKIKSMATSRRAKLSESHRLHQFFRDMDDEESWIKEKKLLVSSEDYGRDL 1776
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
V +L KHK E L E + + +GK+L D++ G + I RLA+ ++ +LK
Sbjct: 1777 TGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGQEEIQQRLAQFVEHWKELK 1836
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
+L+A+R +RL +EY QF + ++ + ++ + + +++SED G +Q LLKKH+
Sbjct: 1837 QLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFE 1896
Query: 2341 DELQNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDAL 2517
+ + + + L ++ H + I ++ + ++LE + RK +L +
Sbjct: 1897 TDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENS 1956
Query: 2518 SLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKN-QEAKVTNV 2694
+ + AD VESWI EK L T GRD+ V+ + + +T + ++ Q+ + N+
Sbjct: 1957 AFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANI 2016
Query: 2695 NDLARQLLNVEHPNSDDILHRQNKLNARWAQL-RDMVDQKRNELERAHRLE-------TF 2850
L QLL +H S I R L RW QL + +K+ LE TF
Sbjct: 2017 TALKDQLLAAKHIQSKAIEARHASLMKRWTQLLANSATRKKKLLEAQSHFRKVEDLFLTF 2076
Query: 2851 RIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEAD 3030
+W E+ L D N L + L+ L + QA + L +
Sbjct: 2077 AKKASAFNSWFENAEEDLTDP-VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDR 2135
Query: 3031 DIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLD------EAGDL--QRFLRDLD 3186
I+ R ++ + + W L K ++E E +L E D Q F + +
Sbjct: 2136 QIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHAN 2195
Query: 3187 HFQAWLTATQRQVAS-----EEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR 3351
F W+ T+ + EE ++ E +H +EI KK+ +G
Sbjct: 2196 AFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKH----QEIRAMRSQLKKIEDLGAA 2251
Query: 3352 VTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQ 3531
+ ++ + GL + W++L ++ QH L Q + + ++A S
Sbjct: 2252 M-EEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSM 2310
Query: 3532 QENYLAKD 3555
+ KD
Sbjct: 2311 MFKHFDKD 2318
>gi|18481635|gb|AAL73492.1| beta I spectrin form betaI sigma3 [Homo
sapiens]
Length = 1028
Score = 648 bits (1671), Expect = 0.0
Identities = 375/1006 (37%), Positives = 547/1006 (54%), Gaps = 96/1006 (9%)
Frame = +1
Query: 3988 LGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQL 4167
L D+KP++ + ++E L WDEL+ TT+EK Q L A L +Q+ AD+ +W + +
Sbjct: 4 LMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAM 63
Query: 4168 ENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKA 4347
E+++ +D DLT+VN + K +E ++ + + + P E
Sbjct: 64 EDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQV-------PSMGEEGGD 116
Query: 4348 HRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLP 4527
L+++++ L PL R+K LE +A Q RD++DE LW+ ERL LA++ + G +L
Sbjct: 117 ADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGTNLQ 176
Query: 4528 DCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKE 4707
K Q L NEI H P + + GQ+L++ + E+++ L+S+W L+E
Sbjct: 177 TVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLRE 236
Query: 4708 AVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQS 4887
A R L ++ +A Q+ D EAEAW+ EQELY++ DE KDE +K+H R Q
Sbjct: 237 AAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQR 296
Query: 4888 DIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXX 5067
++ + I+ LA++A + P EQI Q Q++K YAGL+D
Sbjct: 297 AVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYH 356
Query: 5068 XYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANAN 5247
+ L RE DDL QWI++KE+VA S E GQD++HV +L+++F+ FAR+T IG ERV N N
Sbjct: 357 LFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVN 416
Query: 5248 DGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLS 5427
+ LI GH++A TIA WKD LNE W +LLEL+DTR Q+L AS LH++++ + L
Sbjct: 417 AFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILG 476
Query: 5428 RIMEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKA 5607
I EK +P+D+G D+S+ + R H + +++ +G QV Q + A L+ YAG+KA
Sbjct: 477 LIDEKHRELPEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKA 536
Query: 5608 LDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQER 5787
I ++E EV AW+ L C R ++L+DT+D F+F +M RDLL WM+ + R++ +QER
Sbjct: 537 EAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLFWMESIIRQIETQER 596
Query: 5788 PKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTER 5967
P+DVS VELLM HQ + AEI+ R +NF+AC+ LG LL R+H AS EI +KL ++ + R
Sbjct: 597 PRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRR 656
Query: 5968 AEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKH 6147
EM +WE RWE L+++LEV QF+RDA+VAE+WL AQEPYL S ++G ++ KLIK+H
Sbjct: 657 KEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRH 716
Query: 6148 EAFEKSAFAQEERFLALEKLTTFELKE------------TQHREEETAKRRGPAHIGSPS 6291
EAFEKS + ERF ALEK TT ELKE Q E ETA +H +
Sbjct: 717 EAFEKSTASWAERFAALEKPTTLELKERQIAERPAEETGPQEEEGETAGEAPVSHHAATE 776
Query: 6292 RSTPAAETSF-----------GAQDDGAK------------------------------- 6345
R++P E G DG K
Sbjct: 777 RTSPGEEEGTWPQNLQQPPPPGQHKDGQKSTGDERPTTEPLFKVLDTPLSEGDEPATLPA 836
Query: 6346 -----QGEAFEGTLIRKHTYESLDRKAANR------------------------------ 6420
Q EG L RKH E ++KA+N
Sbjct: 837 PRDHGQSVQMEGYLGRKHDLEGPNKKASNSKGEEGEERRETEEEDEEEEETESVAVEMQQ 896
Query: 6421 -----SWEKLYAVLRQNELSFYKDPKHRDESV--HGEPPMALPGCSVNVASDYQKKKNVL 6579
SW LY VLR +EL+FYKD K+ + HGE P+AL +A++Y+KKK+V
Sbjct: 897 HASHVSWNNLYCVLRNSELTFYKDAKNLALGMPYHGEEPLALRHAICEIAANYKKKKHVF 956
Query: 6580 SLRLPIGAEYLFQCGSEEDMQRWLTELQVATGQAQLEEASRSQTLP 6717
LRL G+E+LF EE+M WL + A ++Q ++Q+LP
Sbjct: 957 KLRLSNGSEWLFHGKDEEEMLSWLQGVSTAINESQSIRV-KAQSLP 1001
Score = 218 bits (556), Expect = 1e-54
Identities = 161/680 (23%), Positives = 320/680 (46%), Gaps = 8/680 (1%)
Frame = +1
Query: 1597 IKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYK 1776
++ +L S+D G L V +L K +E +N+ E + AQ
Sbjct: 63 MEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQV--------------- 107
Query: 1777 PVEPGTIDERSDV---LQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQ 1947
P +E D ++KR+ +LL+ RK++LE ++ Q D+ + ++E+
Sbjct: 108 ---PSMGEEGGDADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLP 164
Query: 1948 VLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRL 2127
+ S D G ++ TV + K++ +N + ++ + G++L + + ++ RL
Sbjct: 165 LAQSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERL 224
Query: 2128 AEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTV 2307
++ ++L+E +A R +RL E Q++ DAD+ + ++ + + S+++ KDE
Sbjct: 225 GHLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGA 284
Query: 2308 QLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQ--RLDTTL-KQKAELEN 2478
++LK+H ++++ ++IK L ++A+ L HP+ Q RL + K A L++
Sbjct: 285 IVMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAG--HPEGEQIIRLQGQVDKHYAGLKD 342
Query: 2479 LSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRF-DTLE 2655
+++ RK++L + L++L + D +E WI EK + ++ G+D + V +++ +F D
Sbjct: 343 VAEERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFAR 402
Query: 2656 QDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAH 2835
+ + +V NVN +L++ H + I ++ LN WA L +++D + L ++
Sbjct: 403 ETGAIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASY 462
Query: 2836 RLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSL 3015
L + E + I++K R L + L D S R + ER+L + ++
Sbjct: 463 DLHRYFYTGAEILGLIDEKHRELPEDVGL--DASTAESFHRVHTAFERELHLLGVQVQQF 520
Query: 3016 HKEADDIERE-RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHF 3192
A ++ ++A+AI+ + + W L +L + D RF
Sbjct: 521 QDVATRLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDL 580
Query: 3193 QAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTD 3372
W+ + RQ+ ++E P+ ++ E L+ H I EI+ ++++ +G+ + Q Q
Sbjct: 581 LFWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQ 640
Query: 3373 PQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAK 3552
+R++L + +E+ W+ R L L + F RDA AE L QE YLA
Sbjct: 641 ASEE-IREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLAS 699
Query: 3553 DDIPQSLEQAENQLKRHQDF 3612
D +++ E +KRH+ F
Sbjct: 700 GDFGHTVDSVEKLIKRHEAF 719
Score = 170 bits (431), Expect = 4e-40
Identities = 160/781 (20%), Positives = 325/781 (41%), Gaps = 3/781 (0%)
Frame = +1
Query: 1774 KPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVL 1953
KP + ++ + L + + EL E+ + L + A+L I E L
Sbjct: 8 KPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWISAMEDQL 67
Query: 1954 SSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAE 2133
S D G+D+ +V+ +LAK K E+ + ++ L L + +E +I R +
Sbjct: 68 RSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLSIEKRFLD 127
Query: 2134 IRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQL 2313
+ + + + K+ S + +L Q D +D ++ + L + S D G + TVQL
Sbjct: 128 LLEPLGRRKKQLESSRAKL-------QISRDLEDETLWVEERLPLAQSADYGTNLQTVQL 180
Query: 2314 LLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQL 2490
+KK+ + +E+ ++ + + + L + A + D+ +RL L +
Sbjct: 181 FMKKNQTLQNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSWDRLREAAAG 240
Query: 2491 RKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKN 2670
R QRL DA + Y DAD E+WI E+ + + +D E +M R ++ +++
Sbjct: 241 RLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQRAVED 300
Query: 2671 QEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETF 2850
+ + A+ LL+ HP + I+ Q +++ +A L+D+ ++++ +LE + L
Sbjct: 301 YGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMYHLFQL 360
Query: 2851 RIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAI-QAKLDSLHKEA 3027
+ + + WI +K ++ S + D V L+ + R+ GAI Q ++D+++
Sbjct: 361 KRETDDLEQWISEK-ELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNVNAFI 419
Query: 3028 DDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLT 3207
+ + EA I E ++++W L + + L + DL R+ +
Sbjct: 420 ERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEILGLID 479
Query: 3208 ATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMF 3387
R++ E+ + AE H A E+ ++ + + R+ +
Sbjct: 480 EKHREL-PEDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGEKAEA 538
Query: 3388 LRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQ 3567
++ + + W+ L R+ L + F A+ + + + P+
Sbjct: 539 IQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLFWMESIIRQIETQERPR 598
Query: 3568 SLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGA 3747
+ E +K HQ ++ + A G+ L Q H A+++I +K + + RR
Sbjct: 599 DVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQVMSRRKE 658
Query: 3748 NREKAQEVLKKLKDALSLQQFLSDCDELREW-IEEKMIRAQDETYRDAKTITSKFVRHQA 3924
EK + ++L+ L + QF D W I ++ A + ++ RH+A
Sbjct: 659 MNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEA 718
Query: 3925 FQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFD 4104
F+ A+ ER L +KP T++ + ++A + E EE+G+ +
Sbjct: 719 FEKSTASWAERFAAL---------EKPT---TLELKERQIAERPAEETGPQEEEGETAGE 766
Query: 4105 A 4107
A
Sbjct: 767 A 767
Score = 150 bits (378), Expect = 5e-34
Identities = 165/771 (21%), Positives = 309/771 (39%), Gaps = 10/771 (1%)
Frame = +1
Query: 2707 RQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAH----RLETFRIDCQETV 2874
+QL++ + + + + L+ W +L+ +K L A RL+T D + +
Sbjct: 2 KQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQT-HADLNKWI 60
Query: 2875 TWIEDKTRVLEDSDALTNDLSGVMKLQR---RLSMMERDLGAIQAKLDSLHKEADDIERE 3045
+ +ED+ R + LT+ + KL+R ++++ + +LG + A++ S+ +E D +
Sbjct: 61 SAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLS 120
Query: 3046 RPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQV 3225
+ + E + R K++ AKL + RDL+ W+
Sbjct: 121 IEKRFLDLLEPLGR-------RKKQLESSRAKL-------QISRDLEDETLWVEERLPLA 166
Query: 3226 ASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLA 3405
S + +L + + ++ ++ EI G+ + + G ++ + + L +RL
Sbjct: 167 QSADYGTNLQTVQLFMKKNQTLQNEILGHTPRVEDVLQRGQQLVE-AAEIDCQDLEERLG 225
Query: 3406 GLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAE 3585
LQ W+ L+ R L Q + DA +AE + +QE Y+ D+IP+ E A
Sbjct: 226 HLQSSWDRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAI 285
Query: 3586 NQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQ 3765
LKRH ++ I+ + L GH ++I + +D+ ++ A+
Sbjct: 286 VMLKRHLRQQRAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAE 345
Query: 3766 EVLKKLKDALSLQQFLSDCDELREWIEEK-MIRAQDETYRDAKTITSKFVRHQAFQSELA 3942
E +KL++ L Q + D+L +WI EK ++ + E +D +T + + F E
Sbjct: 346 ERKRKLENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETG 405
Query: 3943 A-NKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQ 4119
A +ER+D + L D TI + L W +L + + + Q L +
Sbjct: 406 AIGQERVDNVNAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLH 465
Query: 4120 LYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXX 4299
Y + A++ + E+ ED D +T + E E+ +
Sbjct: 466 RYFYTGAEILGLIDEKHRELP-EDVGLDASTAESFHRVHTAFERELHLLGVQVQQFQDVA 524
Query: 4300 XXXXXXHPDE-LENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWI 4476
+ E E I+ V Q L RR L F+F D W+
Sbjct: 525 TRLQTAYAGEKAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSMARDLLFWM 584
Query: 4477 SERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPA 4656
+ + Q + L K Q ++ EI+ + G+ L+ H
Sbjct: 585 ESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEE 644
Query: 4657 FEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGK 4836
+K+Q++ S +E+ E + R L + QF D AEAW+ QE Y+ + G
Sbjct: 645 IREKLQQVMSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGH 704
Query: 4837 DEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQ 4989
S + IK+HE + ++ A+ A +F + P T +++ RQ
Sbjct: 705 TVDSVEKLIKRHEAFE----------KSTASWAERFAALEKPTTLELKERQ 745
Score = 132 bits (331), Expect = 2e-28
Identities = 148/738 (20%), Positives = 303/738 (41%), Gaps = 7/738 (0%)
Frame = +1
Query: 1132 INRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFG 1311
+++ ++L + E + KE+ R A++ + W++ + + D+ G
Sbjct: 15 VSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNK-WISAMEDQLRSDDPG 73
Query: 1312 NDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXX 1491
DL+SV K + +E + +E I +R ++
Sbjct: 74 KDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGDADLSIEKRFLDLLEPLG 133
Query: 1492 XXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRL---LSEDLGAHLMDVEDLLQ 1662
+ R +L++S ++ ++ RL S D G +L V+ ++
Sbjct: 134 RRKKQLESSRAKLQISRDLE----------DETLWVEERLPLAQSADYGTNLQTVQLFMK 183
Query: 1663 KHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELL 1842
K+ L+++I RV + + + Q+ ++ ++ER LQ + L
Sbjct: 184 KNQTLQNEILGHTPRVEDVLQRGQQLVEA--------AEIDCQDLEERLGHLQSSWDRLR 235
Query: 1843 DLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAE 2022
+ AA R +RL D Q++ D E E I EQE + S + +D +L +H +
Sbjct: 236 EAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRHLRQQ 295
Query: 2023 NNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGV 2202
+ D + + +L + L P + I ++ + LK+++ RK +L
Sbjct: 296 RAVEDYGRNIKQLASRAQGLLSAGHPEGEQIIRLQGQVDKHYAGLKDVAEERKRKLENMY 355
Query: 2203 EYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQ-HIKVL 2379
+Q + DD+++++ + V SS ++G+D V LL K D E Q + +
Sbjct: 356 HLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQERVDNV 415
Query: 2380 HAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVE 2556
+A E L E I + D + A+L L R Q L + L++ + +
Sbjct: 416 NAFIERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRYFYTGAEIL 475
Query: 2557 SWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNV-EHP 2733
IDEK + L V G D E E+++ +V D+A +L
Sbjct: 476 GLIDEKHRELPEDV-GLDASTAESFHRVHTAFERELHLLGVQVQQFQDVATRLQTAYAGE 534
Query: 2734 NSDDILHRQNKLNARWAQLRDMVDQKRNEL-ERAHRLETFRIDCQETVTWIEDKTRVLED 2910
++ I +++ +++A W L D +R +L + A + F + ++ + W+E R +E
Sbjct: 535 KAEAIQNKEQEVSAAWQALLDACAGRRTQLVDTADKFRFFSM-ARDLLFWMESIIRQIET 593
Query: 2911 SDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRI 3090
+ D+S V L + + ++ + + + + + + Q ++ IRE ++++
Sbjct: 594 QER-PRDVSSVELLMKYHQGINAEIETRSKNFSACLELGESLLQRQHQASEEIREKLQQV 652
Query: 3091 HQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQL 3270
+N+K +L ++ +F RD +AWL A + +AS + ++ E+L
Sbjct: 653 MSRRKEMNEKWEARWERLRMLLEVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKL 712
Query: 3271 LNQHAAIREEIDGYAEDY 3324
+ +H A + +AE +
Sbjct: 713 IKRHEAFEKSTASWAERF 730
Score = 95.1 bits (235), Expect = 2e-17
Identities = 101/522 (19%), Positives = 206/522 (39%), Gaps = 6/522 (1%)
Frame = +1
Query: 4615 GQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWM 4794
G++L+DE +K++ L W EL+ K++ L + + L + W+
Sbjct: 1 GKQLMDEKPQFTALVSQKLEALHRLWDELQATTKEKTQHLSAARSSDLRLQTHADLNKWI 60
Query: 4795 SEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQ 4974
S E + D+ GKD S + K +R++ ++ + + L + EE
Sbjct: 61 SAMEDQLRSDDPGKDLTSVNRMLAKLKRVEDQVNVRKEELGELFAQVPSMGEEGGD---- 116
Query: 4975 IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQ 5154
IEK + L + + R+++D W+ ++ +A S + G
Sbjct: 117 ---ADLSIEKRFLDLLEPLGRRKKQLESSRAKLQISRDLEDETLWVEERLPLAQSADYGT 173
Query: 5155 DYEHVQMLQERFQQFARDTENIG-SERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAW 5331
+ + VQ+ ++ Q E +G + RV + L+ D + L +W
Sbjct: 174 NLQTVQLFMKKNQTL--QNEILGHTPRVEDVLQRGQQLVEAAEIDCQDLEERLGHLQSSW 231
Query: 5332 ENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIME-KTHAMPDDLGRDSSSVGALSRKH 5508
+ L E R Q L + ++Y D + + I E + + + D++ +D + ++H
Sbjct: 232 DRLREAAAGRLQRLRDANEAQQYYLDADEAEAWIGEQELYVISDEIPKDEEGAIVMLKRH 291
Query: 5509 QNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSR 5688
+ + G + Q+ A L + I + +V K + L+ + + R +
Sbjct: 292 LRQQRAVEDYGRNIKQLASRAQGLLSA-GHPEGEQIIRLQGQVDKHYAGLKDVAEERKRK 350
Query: 5689 LMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDA---- 5856
L + LF+ DL W+ E + +S E +D V LL + + E A
Sbjct: 351 LENMYHLFQLKRETDDLEQWISEKELVASSPEMGQDFDHVTLLRDKFRDFARETGAIGQE 410
Query: 5857 REENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQF 6036
R +N NA I L++ H ++ I + L A+++ + R + L +++++
Sbjct: 411 RVDNVNAFI---ERLIDAGHSEAATIAEWKDGLNEMWADLLELIDTRMQLLAASYDLHRY 467
Query: 6037 ARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEK 6162
A L ++ + ++ G + + H AFE+
Sbjct: 468 FYTGAEILG-LIDEKHRELPEDVGLDASTAESFHRVHTAFER 508
Score = 44.7 bits (104), Expect = 0.032
Identities = 37/175 (21%), Positives = 76/175 (43%), Gaps = 3/175 (1%)
Frame = +1
Query: 874 RYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVL 1053
R+ +++ DLL W+ + I+ + + ++ V+ + + + + LE+
Sbjct: 572 RFFSMARDLLFWMESIIRQIETQERPRDVSSVELLMKYHQGINAEIETRSKNFSACLELG 631
Query: 1054 LFTLQSAMRANNQ-RPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQL- 1227
LQ +A+ + R + + ++N W++ R E+L L
Sbjct: 632 ESLLQRQHQASEEIREKLQQVMSRRKEMNEKWEA-----------------RWERLRMLL 674
Query: 1228 -AARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEER 1389
+F+R A + E WL + ++ +FG+ + SVE K+HEA E ++ ER
Sbjct: 675 EVCQFSRDASVAEAWLIAQEPYLASGDFGHTVDSVEKLIKRHEAFEKSTASWAER 729
>gi|31565122|gb|AAH53521.1| SPTAN1 protein [Homo sapiens]
Length = 2452
Score = 644 bits (1660), Expect = 0.0
Identities = 430/1506 (28%), Positives = 737/1506 (48%), Gaps = 119/1506 (7%)
Frame = +1
Query: 2104 SDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSED 2283
+++I R ++ D ++ KELS R+++L + F DA+++++++ + L++ S E+
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDEN 71
Query: 2284 VGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQ 2460
KD +Q L+KH E+Q I L + E + IR RL +Q
Sbjct: 72 Y-KDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQ 130
Query: 2461 KAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHR 2640
L + + +L+ A L + + + V WI++K ++ + G+D+E VE+++ +
Sbjct: 131 WELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKK 190
Query: 2641 FDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWAQLRDMVDQKRNE 2820
F+ + DM E +V VN A +L+ +HP + I +Q+++NA W +L+ + Q++ +
Sbjct: 191 FEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGK 250
Query: 2821 LERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQA 3000
L A ++ F D ET++WI++K +++ SD DL+ V L R+ +ERDL A++
Sbjct: 251 LFGAAEVQRFNRDVDETISWIKEKEQLMA-SDDFGRDLASVQALLRKHEGLERDLAALED 309
Query: 3001 KLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRD 3180
K+ +L EAD +++ P A I+ + + W+ + E A+L+++ LQRFL D
Sbjct: 310 KVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLAD 369
Query: 3181 LDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRV-- 3354
+W+T + + ++E +A AE LL++H + EID + + +K G +
Sbjct: 370 FRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLA 429
Query: 3355 ----TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVM 3522
D+ +R++L L E L +W+ R+ Q ++LQ+F RD +Q +
Sbjct: 430 AGHYASDE-------VREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNW 482
Query: 3523 LSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQDGHYAAD 3702
+S+QE +L +D+ SL+ E LK+H+DF ++ A +EKI A+ F +L Q+ HYA +
Sbjct: 483 MSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAME 542
Query: 3703 KIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMIRAQDETYR 3882
+ + + RR A E+A +L D+ LQQF D DEL+ W+ EKM A DE Y+
Sbjct: 543 DVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAYK 602
Query: 3883 DAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQIEELATQWDE 4062
D + K +HQAF++EL+AN+ R+D L+ A L D + ++ E+ + W +
Sbjct: 603 DPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKK 662
Query: 4063 LEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHL 4242
L + TE KG KL +AN+QQ + +++ D++ W ++E + +D DLT V +K L
Sbjct: 663 LLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHAL 722
Query: 4243 IETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALER 4422
+E ++ ID + ENIK + A+ + + L+ P+ R++ L
Sbjct: 723 LEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLAD 782
Query: 4423 KKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQ 4602
Q RDV+DE+ WI E+ +A + N G+ L L K Q L EI HEP I
Sbjct: 783 SLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKA 842
Query: 4603 ICNNGQELIDEGHANGPAFEKKIQELRSAW-----------QELKEAVKDRK-------- 4725
+ G +++EGH + K+ EL W Q+L+++++ ++
Sbjct: 843 VTQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEA 902
Query: 4726 -------------GDLGESEKAHQFLYDCGEA-----------------EAWMSEQELYM 4815
D G+ E + + L EA +A Q++
Sbjct: 903 ESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAP 962
Query: 4816 MQDERGKD------EFSTKNQ----IKKHERLQ--------------SDIDKFADTIRAL 4923
DE GK+ ++ K+ +KK + L +D F
Sbjct: 963 TDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVK 1022
Query: 4924 ATKAHKFVEEKSPLTEQ--IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDD 5097
+ ++ L EQ I +RQ QI+ Y L + + L RE ++
Sbjct: 1023 KLDPAQSASRENLLEEQGSIALRQEQIDNQYHSLLELGEKRKGMLEKSCKKFMLFREANE 1082
Query: 5098 LLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHG 5277
L QWI +KE S+E G D E V++LQ++F F +D + R+ + N + L G
Sbjct: 1083 LQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLK-ANESRLKDINKVAEDLESEG 1141
Query: 5278 ---------------------HTDAPTIALWKDS---------------LNEAWENLLEL 5349
TD+ T + WK + LNE W +L +L
Sbjct: 1142 LMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQL 1201
Query: 5350 MDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM-PDDLGRDSSSVGALSRKHQNYLKD 5526
+ R+Q+L ++ + +F+ D + I EK A+ D+ G D +SV AL RKH+ + +D
Sbjct: 1202 AEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERD 1261
Query: 5527 IAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSD 5706
+AA+G++V + A L + + A D+ + +E+ +AW L D R ++L D+ D
Sbjct: 1262 LAALGDKVNSLGETAERLIQSHP-ESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHD 1320
Query: 5707 LFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACIS 5886
L +F++ RDL+ W++ ++ ++S E KDV+G E L+ HQ + EIDAR F A
Sbjct: 1321 LQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQ 1380
Query: 5887 LGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESW 6066
G+ LL HYAS EI++KL L ERA++ + W R L LE+ F RD AE+W
Sbjct: 1381 FGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENW 1440
Query: 6067 LFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREE 6246
+ A+E +L +++ G +L+ LIKKHE F+K+ QEE+ AL+ + + +
Sbjct: 1441 MAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKG 1500
Query: 6247 ETAKRR 6264
+ + RR
Sbjct: 1501 DISSRR 1506
Score = 527 bits (1358), Expect = e-147
Identities = 389/1564 (24%), Positives = 696/1564 (43%), Gaps = 61/1564 (3%)
Frame = +1
Query: 889 SSDLLEWINAKIQLLNERHFEN--NLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFT 1062
S +L W+N K++ + +++ NL+G K + E L
Sbjct: 582 SDELKSWVNEKMKTATDEAYKDPSNLQG------------------KVQKHQAFEAELSA 623
Query: 1063 LQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAAR-- 1236
QS + A + + G+ + D+N + A + L ++L+ +L+ + R
Sbjct: 624 NQSRIDA------LEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKLREA 677
Query: 1237 -----FNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXX 1401
FNR E E WL E + ++ D++G DL++V+ KKH +E D+ A+++R
Sbjct: 678 NQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRIDGI 737
Query: 1402 XXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXX 1581
+ D I +++E + AR+ +L S+ +Q++F
Sbjct: 738 TIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVEDEE 797
Query: 1582 XXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGERVN------NSIAQAQRFR 1743
+ S + G L+ V++LL+KH L+++I R+ N++ + F
Sbjct: 798 TWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEGHFA 857
Query: 1744 NPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELE 1923
D + + L ++++ L A++R++ LED+ + Q++ D E E
Sbjct: 858 AED--------------VKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAE 903
Query: 1924 HGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPG 2103
++E+E ++ STD G+D + LL KH+ ++L + L + + + P
Sbjct: 904 SWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQVAPT 963
Query: 2104 SDNIPPRLA-EIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSE 2280
D L + DY K +K D+ L T +
Sbjct: 964 DDETGKELVLALYDYQEKSPREVTMKK----------------GDILTLLNSTNKDWWKV 1007
Query: 2281 DVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREHPDIRQRLDTTLKQ 2460
+V +G V K K+ A++ S E I R + Q
Sbjct: 1008 EVNDRQGFVPAAYVK---------------KLDPAQSASRENLLEEQGSIALRQEQIDNQ 1052
Query: 2461 KAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHR 2640
L L + RK L + + L+ +A+ ++ WI+EK L + G D+E+VE+++ +
Sbjct: 1053 YHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKK 1112
Query: 2641 FDTLEQDMKNQEAKVTNVNDLARQLLN----------VEHPNSDDILHRQN--------- 2763
FD ++D+K E+++ ++N +A L + V+ ++ R
Sbjct: 1113 FDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPW 1172
Query: 2764 -----------------KLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDK 2892
+LN RW L+ + +++ L AH ++ F D ET WIE+K
Sbjct: 1173 KSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEK 1232
Query: 2893 TRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIR 3072
+ L ++D +DL+ V LQR+ ERDL A+ K++SL + A+ + + P+ A+ ++
Sbjct: 1233 NQAL-NTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQ 1291
Query: 3073 EDIKRIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSL 3252
E ++Q W L K+ + +AKL ++ DLQRFL D +W+ + V+S+E + +
Sbjct: 1292 EKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDV 1351
Query: 3253 AEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQD--QTDPQYMFLRQRLAGLQEGWE 3426
AE LL +H R EID A ++ G ++ P+ ++Q+L L +
Sbjct: 1352 TGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPE---IKQKLDILDQERA 1408
Query: 3427 ELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQ 3606
+L++ W R+ +L Q L LQ+F RD +QAE ++ +E +L +D SL+ E +K+H+
Sbjct: 1409 DLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHE 1468
Query: 3607 DFITTMDANDEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLK 3786
DF ++ +EKI A+ F DQL GHYA I + + +R + + E KL
Sbjct: 1469 DFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLG 1528
Query: 3787 DALSLQQFLSDCDELREWIEEKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQ 3966
++ +LQQF D DE+ WI EK+ A DE+Y+D I SK +HQAF++EL AN +R+
Sbjct: 1529 ESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRI-- 1586
Query: 3967 LKHAAINLGDDKPE------YHGTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYV 4128
I++G+ E + ++ LA QW L + + EK QKL +AN+QQ +
Sbjct: 1587 --RGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFN 1644
Query: 4129 QSIADMKEWATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXX 4308
I D W +++E + ED DL +VN ++K L+E ++ +
Sbjct: 1645 TGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSL 1704
Query: 4309 XXXHPDELENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERL 4488
+ +K R + + Q++++ RR L QF RD+DDE+ WI E+
Sbjct: 1705 MTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKK 1764
Query: 4489 VLAKAQNLGESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKK 4668
+L +++ G L L+K + L E+ HEP I + + G++L D+ +++
Sbjct: 1765 LLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQR 1824
Query: 4669 IQELRSAWQELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFS 4848
+ + W+ELK+ R L ES + QF+ + E EAW++E+ + ++ G +
Sbjct: 1825 LAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAA 1884
Query: 4849 TKNQIKKHERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDX 5028
+ +KKHE ++D D + + T +++ + E I + + + L+
Sbjct: 1885 IQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKA 1944
Query: 5029 XXXXXXXXXXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARD 5208
+ + D + WI +KE + + G+D VQ L + + F
Sbjct: 1945 AAQRKAKLDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAG 2004
Query: 5209 TENIGSERVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTR-AQILEASR 5385
+ E +AN D L+ H + I SL + W LL R ++LEA
Sbjct: 2005 LQAFQQEGIANITALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQS 2064
Query: 5386 LLHK 5397
K
Sbjct: 2065 HFRK 2068
Score = 449 bits (1155), Expect = e-124
Identities = 377/1810 (20%), Positives = 781/1810 (42%), Gaps = 23/1810 (1%)
Frame = +1
Query: 820 KRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFEN--NLEGV--QRQLTE 987
K + + + +E+ ++ + +L +WI K+Q+ ++ ++++ NL+G + Q E
Sbjct: 30 KELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDENYKDPTNLQGKLQKHQAFE 89
Query: 988 FNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAE 1167
K DE G L + S + +++R W+ L +
Sbjct: 90 AEVQANSGAIVKLDETGNLMISEGHFASETIRTR-----------LMELHRQWELLLEKM 138
Query: 1168 HERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTENQRLVSQDNFGNDLSSVEAATKK 1347
E+ + +L++ +KL Q + R+ E W+ + + +V+ + G DL VE KK
Sbjct: 139 REKGI----KLLQAQKLVQ----YLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKK 190
Query: 1348 HEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKENVXXXXXXXXXXXXARRVR 1527
E +TD+ A+EER + ++ I +++ V R+ +
Sbjct: 191 FEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGK 250
Query: 1528 LELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVEDLLQKHALLESDINIIGER 1707
L + +Q+ + + S+D G L V+ LL+KH LE D+ + ++
Sbjct: 251 LFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAALEDK 310
Query: 1708 VNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRYKELLDLAAERKRRLEDNKR 1887
V A+A R + P+ I + + L ++++ LAAER RL D+ R
Sbjct: 311 VKALCAEADRLQQS--------HPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYR 362
Query: 1888 LCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDV 2067
L +F D +L + E + ++++ + D+ LL +H+ + + E D
Sbjct: 363 LQRFLADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADE 422
Query: 2068 SGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRY 2247
SG+ L SD + +L + + L EL R+++ ++ F+ D + VD +
Sbjct: 423 SGQALLAAGHYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNW 482
Query: 2248 LYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAR-EHP 2424
+ + +ED+G +V+ LLKKH+D L ++ I L A L Q
Sbjct: 483 MSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAME 542
Query: 2425 DIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVPG 2604
D+ R D L ++ L + R+ +L D+ L + + D+D ++SW++EK K AT
Sbjct: 543 DVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMK-TATDEAY 601
Query: 2605 RDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARWA 2784
+D ++ + E ++ ++++ + ++L++V H D++ R N++ + W
Sbjct: 602 KDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWK 661
Query: 2785 QLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRL 2964
+L + + K +L A++ + F + ++ W+ + L SD DL+ V LQ++
Sbjct: 662 KLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLA-SDDYGKDLTNVQNLQKKH 720
Query: 2965 SMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKL 3144
+++E D+ A Q ++D + +A + +A+ I++ + + ++ L + + + KL
Sbjct: 721 ALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKL 780
Query: 3145 DEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYAEDY 3324
++ LQ+ RD++ + W+ + AS + L + LL +H A++ EI G+
Sbjct: 781 ADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRI 840
Query: 3325 KKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDA 3504
K + G+ + ++ ++ +L L + WE L+ R+ L L Q + DA
Sbjct: 841 KAVTQKGNAMVEEGHFAA-EDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADA 899
Query: 3505 KQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQLCQD 3684
+AE + ++E + D + + AE LK+H+ ++ + A I+A+ Q
Sbjct: 900 NEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQQ 959
Query: 3685 GHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLS------DCDELREWIE 3846
D+ K+ + + +EV K D L+L + + ++ + ++
Sbjct: 960 VAPTDDETGKEL--VLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWKVEVNDRQGFVP 1017
Query: 3847 EKMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTID 4026
++ D A++ + + + + Q +A +E++D H+ + LG+ + G ++
Sbjct: 1018 AAYVKKLD----PAQSASRENLLEE--QGSIALRQEQIDNQYHSLLELGEKR---KGMLE 1068
Query: 4027 PQIEE--LATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPG 4200
++ L + +EL++ EK L Q K++ ++ E +
Sbjct: 1069 KSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKDLKANESRLK 1128
Query: 4201 DLTTVNVAMQKQHLI--ETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLA----- 4359
D+ V ++ + L+ E + +++ + P + + H +A
Sbjct: 1129 DINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKSARLMVHTVATFNSI 1188
Query: 4360 --VQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDC 4533
+ E+ + LQ ++R + L +F RD D+ K WI E+ N G L
Sbjct: 1189 KELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQALNTDNYGHDLASV 1248
Query: 4534 HRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAV 4713
LQ+ + ++ +N + + LI + ++K EL AW L +
Sbjct: 1249 QALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRA 1308
Query: 4714 KDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDI 4893
RK LG+S +FL D + +W++ + DE KD + +++H+ +++I
Sbjct: 1309 DQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGAEALLERHQEHRTEI 1368
Query: 4894 DKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXY 5073
D A T +A + + + +I+ + +++ A L+
Sbjct: 1369 DARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQ 1428
Query: 5074 ALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDG 5253
HR+ + W+A +E +++ G + V+ L ++ + F + N+ E++A
Sbjct: 1429 LFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDK-AINVQEEKIAALQAF 1487
Query: 5254 CDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRI 5433
D LI GH I+ ++ + + W L M + L S+ L +F D + + I
Sbjct: 1488 ADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWI 1547
Query: 5434 MEKTHAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQV-AQIERDAAELRDGYAGDKAL 5610
EK D+ +D +++ + +KHQ + ++ A +++ I+ + + G
Sbjct: 1548 SEKLQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAGSED 1607
Query: 5611 DIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERP 5790
+ +R + + W+ L ++ +L + + F ++D W+ EV+ + S++
Sbjct: 1608 AVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYG 1667
Query: 5791 KDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERA 5970
KD++ V L+ HQ L+A+I A E+ S L+ + +S+++ K +
Sbjct: 1668 KDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQ 1727
Query: 5971 EMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHE 6150
++ R L ++QF RD ESW+ ++ + S++YGR+L L KKH+
Sbjct: 1728 KIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHK 1787
Query: 6151 AFEKSAFAQE 6180
E A E
Sbjct: 1788 RLEAELAAHE 1797
Score = 443 bits (1139), Expect = e-122
Identities = 415/1946 (21%), Positives = 814/1946 (41%), Gaps = 61/1946 (3%)
Frame = +1
Query: 610 DLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAEDVNVDQPDEKSIITYVVTYYHYF 789
DL + LQK Q+ E ++ A+ + P+E+ I T +
Sbjct: 180 DLEHVEVLQKK--FEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAW 237
Query: 790 NKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGV 969
+LK +Q R GK+ + R+ + + WI K QL+ F +L V
Sbjct: 238 QRLKGLALQ--RQGKLFGAAE-----VQRFNRDVDETISWIKEKEQLMASDDFGRDLASV 290
Query: 970 QRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQ 1149
Q L + LE L L+ ++A L A+ +R Q
Sbjct: 291 QALLRKHEG---------------LERDLAALEDKVKA------------LCAEADRLQQ 323
Query: 1150 SLEKAEHERELVLKEELIRQEKLEQLAARFNRK-----------AEMRE--TWLTENQRL 1290
S + + ++ +E + E++ LAA + + A+ R+ +W+TE + L
Sbjct: 324 SHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFLADFRDLTSWVTEMKAL 383
Query: 1291 VSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNYHDQAKINERKE 1470
++ D +D++ EA +H+ + +I A+E+ ++ ++ E+
Sbjct: 384 INADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQALLAAGHYASDEVREKLT 443
Query: 1471 NVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSEDLGAHLMDVE 1650
+ RR + E M +Q + ++ LL+EDLG L VE
Sbjct: 444 VLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDNWMSKQEAFLLNEDLGDSLDSVE 503
Query: 1651 DLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTIDERSDVLQKRY 1830
LL+KH E ++ E++ A + + Y + T R D L R
Sbjct: 504 ALLKKHEDFEKSLSAQEEKITALDEFATKLIQ-----NNHYAMEDVAT---RRDALLSRR 555
Query: 1831 KELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKH 2010
L + A R+ +L D+ L QF+ D EL+ + E+ + ++ + +D + + KH
Sbjct: 556 NALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKT-ATDEAYKDPSNLQGKVQKH 614
Query: 2011 KNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERL 2190
+ E L + +D L+ +G++L D + D + R+ E+ KL E + + +L
Sbjct: 615 QAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLWKKLLEATELKGIKL 674
Query: 2191 AGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHI 2370
+ QF + +D++ +LY+ ++S+D GKD VQ L KKH + ++ I
Sbjct: 675 REANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKHALLEADVAAHQDRI 734
Query: 2371 KVLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDAD 2547
+ +A + +I+++ + + + L+ RKQ+L D+L L +L+ D +
Sbjct: 735 DGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKLADSLRLQQLFRDVE 794
Query: 2548 SVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVE 2727
E+WI EK + A+ G+D+ V+ + + L+ ++ E ++ V ++
Sbjct: 795 DEETWIREKEPIAASTNRGKDLIGVQNLLKKHQALQAEIAGHEPRIKAVTQKGNAMVEEG 854
Query: 2728 HPNSDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLE 2907
H ++D+ + ++LN +W L+ Q+R +LE + + + + D E +W+ +K ++
Sbjct: 855 HFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFADANEAESWMREKEPIVG 914
Query: 2908 DSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERE-RPQEAQAIREDIK 3084
+D ++ S L++ ++M DL A + + +L ++A ++ P + + +E +
Sbjct: 915 STDYGKDEDSAEALLKKHEALMS-DLSAYGSSIQALREQAQSCRQQVAPTDDETGKELVL 973
Query: 3085 RIHQVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQ------VASEEEPQ 3246
++ D K RE K GD+ L + + RQ + +P
Sbjct: 974 ALY---DYQEKSPREVTMK---KGDILTLLNSTNKDWWKVEVNDRQGFVPAAYVKKLDPA 1027
Query: 3247 SLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWE 3426
A E LL + +I + Q+Q D QY
Sbjct: 1028 QSASRENLLEEQGSIA-------------------LRQEQIDNQY--------------H 1054
Query: 3427 ELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQ 3606
L + + R+ +L + M R+A + + ++++E L +++ LEQ E K+
Sbjct: 1055 SLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFD 1114
Query: 3607 DFITTMDANDEKIRAVGMFGDQLCQDGHYAAD---------------------------- 3702
DF + AN+ +++ + + L +G A +
Sbjct: 1115 DFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDSKTASPWKS 1174
Query: 3703 ---KIHKKA-----RNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEKMI 3858
+H A + ++ER + ++ A+E + L A +Q+F D DE +EWIEEK
Sbjct: 1175 ARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQRFHRDADETKEWIEEKNQ 1234
Query: 3859 RAQDETY-RDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDPQI 4035
+ Y D ++ + +H+ F+ +LAA ++++ L A L PE + +
Sbjct: 1235 ALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAERLIQSHPESAEDLQEKC 1294
Query: 4036 EELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQPGDLTTV 4215
EL W L K +++ KL D++ Q ++ D+ W + ++ ++ D+T
Sbjct: 1295 TELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWINGIRGLVSSDELAKDVTGA 1354
Query: 4216 NVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRLQAPL 4395
+++ TE+ +A IK + ++ L+
Sbjct: 1355 EALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYASPEIKQKLDILDQERADLEKAW 1414
Query: 4396 DDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNLQLLSNEI 4575
RR L++ F RD + + W++ R ++ G+SL L K + I
Sbjct: 1415 VQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDKGDSLDSVEALIKKHEDFDKAI 1474
Query: 4576 DNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEAVKDRKGDLGESEKAH 4755
+ E I + +LI GH + E+ W+ LK + +++ LGES+
Sbjct: 1475 NVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRWRRLKAQMIEKRSKLGESQTLQ 1534
Query: 4756 QFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFADTIRALATKA 4935
QF D E EAW+SE+ L DE KD + +++ +KH+ ++++ AD IR +
Sbjct: 1535 QFSRDVDEIEAWISEK-LQTASDESYKDPTNIQSKHQKHQAFEAELHANADRIRGVIDMG 1593
Query: 4936 HKFVEEKSPLTEQ--IQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHREIDDLLQW 5109
+ +E + + ++ R A + + L + I D W
Sbjct: 1594 NSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFW 1653
Query: 5110 IADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLIGHGHTDA 5289
+++ E + S++ G+D V L ++ Q D + +R+ + N D+L+ D
Sbjct: 1654 LSEVEALLASEDYGKDLASVNNLLKKHQLLEADI-SAHEDRLKDLNSQADSLMTSSAFDT 1712
Query: 5290 PTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHDCRDCLSRIMEKTHAM-PDDL 5466
+ +D++N ++ + + +R L S LH+F+ D D S I EK + +D
Sbjct: 1713 SQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDY 1772
Query: 5467 GRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRDGYAGDKALDIGSRESEVVKA 5646
GRD + V L +KH+ ++AA + + +L D K +I R ++ V+
Sbjct: 1773 GRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKE-EIQQRLAQFVEH 1831
Query: 5647 WRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKREMNSQERPKDVSGVELLMNN 5826
W+ L+ L AR RL ++ + +F+ V + W++E + S++ ++ ++ L+
Sbjct: 1832 WKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKK 1891
Query: 5827 HQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKLIKLTTERAEMMRRWEDRWEY 6006
H++ + + ++ N + G+DL+ + ++ I K+ L + +++ + R
Sbjct: 1892 HEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAK 1951
Query: 6007 LQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEETIKLIKKHEAFEKSAFAQEER 6186
L QF A V ESW+ +E L + +YGR+L L+ K E F+ A ++
Sbjct: 1952 LDENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQE 2011
Query: 6187 FLALEKLTTFELKETQHREEETAKRR 6264
+A +L +H + + + R
Sbjct: 2012 GIANITALKDQLLAAKHVQSKAIEAR 2037
Score = 390 bits (1003), Expect = e-106
Identities = 383/1837 (20%), Positives = 771/1837 (41%), Gaps = 66/1837 (3%)
Frame = +1
Query: 895 DLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSA 1074
DL W+ L+N +++ G + L ++ KGE++ + +SA
Sbjct: 372 DLTSWVTEMKALINADELASDVAGAEALLDRHQEH-----------KGEIDAHEDSFKSA 420
Query: 1075 MRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLA--ARFNRK 1248
+ + G +D R + L ER +L+ +R+++ EQ F R
Sbjct: 421 DESGQA---LLAAGHYASDEVR--EKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRD 475
Query: 1249 AEMRETWLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXX 1428
E + W+++ + + ++ G+ L SVEA KKHE E + A EE+
Sbjct: 476 TEQVDNWMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQ 535
Query: 1429 XNYHDQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSR 1608
N++ + R++ + RR +L S +Q+ F K +
Sbjct: 536 NNHYAMEDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNE-KMK 594
Query: 1609 LLSEDLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEP 1788
+++ +++ +QKH E++++ R++ Q+ D + Y E
Sbjct: 595 TATDEAYKDPSNLQGKVQKHQAFEAELSANQSRIDALEKAGQKLI-----DVNHYAKDE- 648
Query: 1789 GTIDERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDT 1968
+ R + + +K+LL+ + +L + + QF +V ++E + E E L+S D
Sbjct: 649 --VAARMNEVISLWKKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDY 706
Query: 1969 GRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYI 2148
G+D+ V +L KH E ++ + +D + + ++ QD ++NI + +
Sbjct: 707 GKDLTNVQNLQKKHALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARY 766
Query: 2149 NKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKH 2328
LKE +RK++LA + Q F D +D + ++ + + +S + GKD VQ LLKKH
Sbjct: 767 EALKEPMVARKQKLADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKH 826
Query: 2329 DDVHDELQNFDQHIKVLHAKAESLPQEAR-EHPDIRQRLDTTLKQKAELENLSQLRKQRL 2505
+ E+ + IK + K ++ +E D++ +L ++ L+ + R+Q L
Sbjct: 827 QALQAEIAGHEPRIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDL 886
Query: 2506 IDALSLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKNQEAKV 2685
D+L + ++DA+ ESW+ EK ++ + G+D + E + + + L D+ + +
Sbjct: 887 EDSLQAQQYFADANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSI 946
Query: 2686 TNVNDLARQLLNVEHPNSD--------------------------DILHRQNKLNARWAQ 2787
+ + A+ P D DIL N N W +
Sbjct: 947 QALREQAQSCRQQVAPTDDETGKELVLALYDYQEKSPREVTMKKGDILTLLNSTNKDWWK 1006
Query: 2788 LRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKL-QRRL 2964
+ V+ ++ + A+ + +E++ + + + N +++L ++R
Sbjct: 1007 VE--VNDRQGFVPAAYVKKLDPAQSASRENLLEEQGSIALRQEQIDNQYHSLLELGEKRK 1064
Query: 2965 SMMERDLGAIQAKLDSLHKEADDI-----ERERPQEAQAIREDIKRIHQV---WDILNKK 3120
M+E+ K L +EA+++ E+E ++ + D++++ + +D K
Sbjct: 1065 GMLEKS-----CKKFMLFREANELQQWINEKEAALTSEEVGADLEQVEVLQKKFDDFQKD 1119
Query: 3121 VREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREE 3300
++ +E++L D+ + DL+ L A + Q ++E + R+E
Sbjct: 1120 LKANESRLK---DINKVAEDLE--SEGLMAEEVQAVQQQEVYGMMP-----------RDE 1163
Query: 3301 IDGY-AEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGL 3477
D A +K R M V + + L E W LQ++ + R LL
Sbjct: 1164 TDSKTASPWKSARLMVHTVATFNS----------IKELNERWRSLQQLAEERSQLLGSAH 1213
Query: 3478 NLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVG 3657
+Q F RDA + + + ++ L D+ L + ++H+ F + A +K+ ++G
Sbjct: 1214 EVQRFHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLG 1273
Query: 3658 MFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELRE 3837
++L Q +A+ + +K +++ + ++A + KL D+ LQ+FLSD +L
Sbjct: 1274 ETAERLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMS 1333
Query: 3838 WIEE-KMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYH 4014
WI + + + DE +D + RHQ ++E+ A + L
Sbjct: 1334 WINGIRGLVSSDELAKDVTGAEALLERHQEHRTEIDARAGTFQAFEQFGQQLLAHGHYAS 1393
Query: 4015 GTIDPQIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKEWATQLENEMTREDQ 4194
I +++ L + +LEK ++ L QL+ + + W E + ED+
Sbjct: 1394 PEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDK 1453
Query: 4195 PGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDELENIKAHRLAVQEQL 4374
L +V ++K + + + + I +I + R V ++
Sbjct: 1454 GDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRW 1513
Query: 4375 QRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNLGESLPDCHRLQKNL 4554
+RL+A + ++R L + QF RDVD+ + WISE+L A ++ + + QK+
Sbjct: 1514 RRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTASDESYKDPTNIQSKHQKH- 1572
Query: 4555 QLLSNEIDNHEPWINQICNNGQELIDEGHANGP--AFEKKIQELRSAWQELKEAVKDRKG 4728
Q E+ + I + + G LI+ G G A + ++ L WQ L + ++
Sbjct: 1573 QAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKSQ 1632
Query: 4729 DLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKHERLQSDIDKFAD 4908
L E+ K F + + W+SE E + ++ GKD S N +KKH+ L++DI D
Sbjct: 1633 KLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHED 1692
Query: 4909 TIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXXXXXXXXYALHRE 5088
++ L ++A + + T Q++ ++ I + ++ + R+
Sbjct: 1693 RLKDLNSQADSLMTSSAFDTSQVKDKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRD 1752
Query: 5089 IDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSERVANANDGCDTLI 5268
+DD WI +K+++ GS++ G+D VQ L+++ ++ + +A ++
Sbjct: 1753 MDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAE--------LAAHEPAIQGVL 1804
Query: 5269 GHGHTDAPTIALWKDSLN-------EAWENLLELMDTRAQILEASRLLHKFYHDCRDCLS 5427
G + + K+ + E W+ L +L R Q LE S +F + + +
Sbjct: 1805 DTGKKLSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEA 1864
Query: 5428 RIMEK-THAMPDDLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAEL------RD 5586
I EK T +D G +++ L +KH+ + D ++V + + +L +
Sbjct: 1865 WINEKMTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHE 1924
Query: 5587 GYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLL-LWMDEVK 5763
K + + S++ KA A+ +D + F N D++ W+ E +
Sbjct: 1925 ENISSKMKGLNGKVSDLEKA--------AAQRKAKLDENSAFLQFNWKADVVESWIGEKE 1976
Query: 5764 REMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRD-LLNRKHYASSEIE- 5937
+ + + +D+S V+ L+ ++ A + A ++ A I+ +D LL KH S IE
Sbjct: 1977 NSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEA 2036
Query: 5938 ------KKLIKLTTERAEMMRRWEDRWEYLQLILEVY-QFARDAAVAESWLFAQEPYLIS 6096
K+ +L A ++ + + + + +++ FA+ A+ SW E L
Sbjct: 2037 RHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTFAKKASAFNSWFENAEEDLTD 2096
Query: 6097 KEYGRNLEETIKLIKKHEAFEKSAFAQEERFLALEKL 6207
+LEE L + H+AF S + + F L +L
Sbjct: 2097 PVRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAEL 2133
Score = 301 bits (771), Expect = 1e-79
Identities = 279/1204 (23%), Positives = 517/1204 (42%), Gaps = 10/1204 (0%)
Frame = +1
Query: 2737 SDDILHRQNKLNARWAQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSD 2916
++DI R+ ++ R+ + +++ +R +LE ++R + F+ D +E WI++K ++ D +
Sbjct: 12 AEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDEN 71
Query: 2917 ALT-NDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEADDIERERPQEAQAIREDIKRIH 3093
+L G KLQ+ + E ++ A + L + + + E ++ IR + +H
Sbjct: 72 YKDPTNLQG--KLQKHQAF-EAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELH 128
Query: 3094 QVWDILNKKVREHEAKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLL 3273
+ W++L +K+RE KL +A L ++LR+ + W+ + V SEE Q L E L
Sbjct: 129 RQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQ 188
Query: 3274 NQHAAIREEIDGYAEDYKKMRAMGDRVTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNR 3453
+ + ++ + E ++ ++ Q+Q P+ ++ + + W+ L+ + R
Sbjct: 189 KKFEEFQTDMAAHEERVNEVNQFAAKLIQEQ-HPEEELIKTKQDEVNAAWQRLKGLALQR 247
Query: 3454 QHLLSQGLNLQMFLRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDAN 3633
Q L +Q F RD + + ++E +A DD + L + L++H+ + A
Sbjct: 248 QGKLFGAAEVQRFNRDVDETISWIKEKEQLMASDDFGRDLASVQALLRKHEGLERDLAAL 307
Query: 3634 DEKIRAVGMFGDQLCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFL 3813
++K++A+ D+L Q +A +I K + R A E +L D+ LQ+FL
Sbjct: 308 EDKVKALCAEADRLQQSHPLSATQIQVKREELITNWEQIRTLAAERHARLNDSYRLQRFL 367
Query: 3814 SDCDELREWIEE-KMIRAQDETYRDAKTITSKFVRHQAFQSELAANKERL---DQLKHAA 3981
+D +L W+ E K + DE D + RHQ + E+ A+++ D+ A
Sbjct: 368 ADFRDLTSWVTEMKALINADELASDVAGAEALLDRHQEHKGEIDAHEDSFKSADESGQAL 427
Query: 3982 INLGDDKPEYHGTIDPQIEELATQWDE---LEKTTEEKGQKLFDANRQQLYVQSIADMKE 4152
+ G H D E+L +E L + E + Q+ QL+ + +
Sbjct: 428 LAAG------HYASDEVREKLTVLSEERAALLELWELRRQQYEQCMDLQLFYRDTEQVDN 481
Query: 4153 WATQLENEMTREDQPGDLTTVNVAMQKQHLIETEMIKKAQHIDXXXXXXXXXXXXHPDEL 4332
W ++ E + ED L +V ++K E + + + I + +
Sbjct: 482 WMSKQEAFLLNEDLGDSLDSVEALLKKHEDFEKSLSAQEEKITALDEFATKLIQNNHYAM 541
Query: 4333 ENIKAHRLAVQEQLQRLQAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKAQNL 4512
E++ R A+ + L RR L QF RD D+ K W++E++ A +
Sbjct: 542 EDVATRRDALLSRRNALHERAMRRRAQLADSFHLQQFFRDSDELKSWVNEKMKTATDEAY 601
Query: 4513 GESLPDCHRLQKNLQLLSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAW 4692
+ ++QK+ Q E+ ++ I+ + GQ+LID H ++ E+ S W
Sbjct: 602 KDPSNLQGKVQKH-QAFEAELSANQSRIDALEKAGQKLIDVNHYAKDEVAARMNEVISLW 660
Query: 4693 QELKEAVKDRKGDLGESEKAHQFLYDCGEAEAWMSEQELYMMQDERGKDEFSTKNQIKKH 4872
++L EA + + L E+ + QF + + E W+ E E ++ D+ GKD + +N KKH
Sbjct: 661 KKLLEATELKGIKLREANQQQQFNRNVEDIELWLYEVEGHLASDDYGKDLTNVQNLQKKH 720
Query: 4873 ERLQSDIDKFADTIRALATKAHKFVEEKSPLTEQIQVRQAQIEKLYAGLQDXXXXXXXXX 5052
L++D+ D I + +A +F + E I+ +Q + Y L++
Sbjct: 721 ALLEADVAAHQDRIDGITIQARQFQDAGHFDAENIKKKQEALVARYEALKEPMVARKQKL 780
Query: 5053 XXXXXXYALHREIDDLLQWIADKEVVAGSQENGQDYEHVQMLQERFQQFARDTENIGSE- 5229
L R+++D WI +KE +A S G+D VQ L ++ Q A E G E
Sbjct: 781 ADSLRLQQLFRDVEDEETWIREKEPIAASTNRGKDLIGVQNLLKKHQ--ALQAEIAGHEP 838
Query: 5230 RVANANDGCDTLIGHGHTDAPTIALWKDSLNEAWENLLELMDTRAQILEASRLLHKFYHD 5409
R+ + ++ GH A + LN+ WE L R Q LE S +++ D
Sbjct: 839 RIKAVTQKGNAMVEEGHFAAEDVKAKLHELNQKWEALKAKASQRRQDLEDSLQAQQYFAD 898
Query: 5410 CRDCLSRIMEKTHAMPD-DLGRDSSSVGALSRKHQNYLKDIAAIGEQVAQIERDAAELRD 5586
+ S + EK + D G+D S AL +KH+ + D++A G + + A R
Sbjct: 899 ANEAESWMREKEPIVGSTDYGKDEDSAEALLKKHEALMSDLSAYGSSIQALREQAQSCRQ 958
Query: 5587 GYAGDKALDIGSRESEVVKAWRHLRGLCDARTSRLMDTSDLFKFMNMVRDLLLWMDEVKR 5766
A E+V A + + M D+ +N D K
Sbjct: 959 QVAPTD----DETGKELVLALYDYQEKSPREVT--MKKGDILTLLNSTNK-----DWWKV 1007
Query: 5767 EMNSQERPKDVSGVELLMNNHQSLKAEIDAREENFNACISLGRDLLNRKHYASSEIEKKL 5946
E+N ++ + V+ L + QS E E+ I+L ++ ++ ++++ E+ +K
Sbjct: 1008 EVNDRQGFVPAAYVKKL-DPAQSASRENLLEEQG---SIALRQEQIDNQYHSLLELGEK- 1062
Query: 5947 IKLTTERAEMMRRWEDRWEYLQLILEVYQFARDAAVAESWLFAQEPYLISKEYGRNLEET 6126
R L+ + + R+A + W+ +E L S+E G +LE+
Sbjct: 1063 ----------------RKGMLEKSCKKFMLFREANELQQWINEKEAALTSEEVGADLEQV 1106
Query: 6127 IKLIKKHEAFEKSAFAQEERFLALEKLTTFELKETQHREEETAKRRGPAHIGSPSRSTPA 6306
L KK + F+K A E R + K+ E EE A ++ + P T +
Sbjct: 1107 EVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYGMMPRDETDS 1166
Query: 6307 AETS 6318
S
Sbjct: 1167 KTAS 1170
Score = 275 bits (704), Expect = 9e-72
Identities = 260/1212 (21%), Positives = 514/1212 (41%), Gaps = 63/1212 (5%)
Frame = +1
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
+Q I R+E + R+ LE S +F ++ L SE
Sbjct: 1038 EQGSIALRQEQIDNQYHSLLELGEKRKGMLEKSCKKFMLFREANELQQWINEKEAALTSE 1097
Query: 1621 DLGAHLMDVEDLLQKHALLESD----------INIIGERVNNSIAQAQRFRNPDGPDGSG 1770
++GA L VE L +K + D IN + E + + A+ + + G
Sbjct: 1098 EVGADLEQVEVLQKKFDDFQKDLKANESRLKDINKVAEDLESEGLMAEEVQAVQQQEVYG 1157
Query: 1771 YKPVEPGTIDERSD------------------VLQKRYKELLDLAAERKRRLEDNKRLCQ 1896
P + S L +R++ L LA ER + L + +
Sbjct: 1158 MMPRDETDSKTASPWKSARLMVHTVATFNSIKELNERWRSLQQLAEERSQLLGSAHEVQR 1217
Query: 1897 FWWDVAELEHGIKEQEQVLSSTDTGRDIVTVSHLLAKHKNAENNLRDLEKYLDRLDVSGK 2076
F D E + I+E+ Q L++ + G D+ +V L KH+ E +L L ++ L + +
Sbjct: 1218 FHRDADETKEWIEEKNQALNTDNYGHDLASVQALQRKHEGFERDLAALGDKVNSLGETAE 1277
Query: 2077 ELQDESIPGSDNIPPRLAEIRDYINKLKELSASRKERLAGGVEYYQFFTDADDVDRYLYD 2256
L ++++ + E+ + L + + RK +L + +F +D D+ ++
Sbjct: 1278 RLIQSHPESAEDLQEKCTELNQAWSSLGKRADQRKAKLGDSHDLQRFLSDFRDLMSWING 1337
Query: 2257 TLRVMSSEDVGKDEGTVQLLLKKHDDVHDELQNFDQHIKVLHAKAESLPQEAREH----- 2421
++SS+++ KD + LL++H + E+ D A E Q+ H
Sbjct: 1338 IRGLVSSDELAKDVTGAEALLERHQEHRTEI---DARAGTFQA-FEQFGQQLLAHGHYAS 1393
Query: 2422 PDIRQRLDTTLKQKAELENLSQLRKQRLIDALSLYKLYSDADSVESWIDEKGKLLATLVP 2601
P+I+Q+LD +++A+LE R+ L L L + D + E+W+ + L T
Sbjct: 1394 PEIKQKLDILDQERADLEKAWVQRRMMLDQCLELQLFHRDCEQAENWMAAREAFLNTEDK 1453
Query: 2602 GRDIEEVEIMKHRFDTLEQDMKNQEAKVTNVNDLARQLLNVEHPNSDDILHRQNKLNARW 2781
G ++ VE + + + ++ + QE K+ + A QL+ H DI R+N++ RW
Sbjct: 1454 GDSLDSVEALIKKHEDFDKAINVQEEKIAALQAFADQLIAAGHYAKGDISSRRNEVLDRW 1513
Query: 2782 AQLRDMVDQKRNELERAHRLETFRIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRR 2961
+L+ + +KR++L + L+ F D E WI +K + SD D + + ++
Sbjct: 1514 RRLKAQMIEKRSKLGESQTLQQFSRDVDEIEAWISEKLQTA--SDESYKDPTNIQSKHQK 1571
Query: 2962 LSMMERDLGAIQAKLDSLHKEADD-IERERPQEAQ-AIREDIKRIHQVWDILNKKVREHE 3135
E +L A ++ + + IER ++ A++ + + W L +K E
Sbjct: 1572 HQAFEAELHANADRIRGVIDMGNSLIERGACAGSEDAVKARLAALADQWQFLVQKSAEKS 1631
Query: 3136 AKLDEAGDLQRFLRDLDHFQAWLTATQRQVASEEEPQSLAEAEQLLNQHAAIREEIDGYA 3315
KL EA Q F + F WL+ + +ASE+ + LA LL +H + +I +
Sbjct: 1632 QKLKEANKQQNFNTGIKDFDFWLSEVEALLASEDYGKDLASVNNLLKKHQLLEADISAHE 1691
Query: 3316 EDYKKMRAMGDRV-TQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMF 3492
+ K + + D + T D + + + + +++++ M +R+ L++ L F
Sbjct: 1692 DRLKDLNSQADSLMTSSAFDTSQV--KDKRDTINGRFQKIKSMAASRRAKLNESHRLHQF 1749
Query: 3493 LRDAKQAEVMLSQQENYLAKDDIPQSLEQAENQLKRHQDFITTMDANDEKIRAVGMFGDQ 3672
RD E + +++ + +D + L +N K+H+ + A++ I+ V G +
Sbjct: 1750 FRDMDDEESWIKEKKLLVGSEDYGRDLTGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKK 1809
Query: 3673 LCQDGHYAADKIHKKARNIDERRGANREKAQEVLKKLKDALSLQQFLSDCDELREWIEEK 3852
L D ++I ++ E ++ A ++L+++L QQF+++ +E WI EK
Sbjct: 1810 LSDDNTIGKEEIQQRLAQFVEHWKELKQLAAARGQRLEESLEYQQFVANVEEEEAWINEK 1869
Query: 3853 MIRAQDETYRDA-KTITSKFVRHQAFQSELAANKERLDQLKHAAINLGDDKPEYHGTIDP 4029
M E Y D I +H+AF+++ +K+R++ + +L + I
Sbjct: 1870 MTLVASEDYGDTLAAIQGLLKKHEAFETDFTVHKDRVNDVCTNGQDLIKKNNHHEENISS 1929
Query: 4030 QIEELATQWDELEKTTEEKGQKLFDANRQQLYVQSIADMKE-WATQLENEMTREDQPGDL 4206
+++ L + +LEK ++ KL D N L AD+ E W + EN + +D DL
Sbjct: 1930 KMKGLNGKVSDLEKAAAQRKAKL-DENSAFLQFNWKADVVESWIGEKENSLKTDDYGRDL 1988
Query: 4207 TTVNVAMQKQHLIETEMIKKAQH-IDXXXXXXXXXXXXHPDELENIKAHRLAVQEQLQRL 4383
++V + KQ + + Q I + + I+A ++ ++ +L
Sbjct: 1989 SSVQTLLTKQETFDAGLQAFQQEGIANITALKDQLLAAKHVQSKAIEARHASLMKRWSQL 2048
Query: 4384 QAPLDDRRKALERKKAAFQFGRDVDDEKLWISERLVLAKA--QNLGESLPD---CHRLQK 4548
A R+K L ++ F R V+D L +++ + +N E L D C+ L++
Sbjct: 2049 LANSAARKKKLLEAQSHF---RKVEDLFLTFAKKASAFNSWFENAEEDLTDPVRCNSLEE 2105
Query: 4549 NLQL------LSNEIDNHEPWINQICNNGQELIDEGHANGPAFEKKIQELRSAWQELKEA 4710
L + + + + NQ+ +++ A+ P ++ L W+ L++
Sbjct: 2106 IKALREAHDAFRSSLSSAQADFNQLAELDRQIKSFRVASNPYTWFTMEALEETWRNLQKI 2165
Query: 4711 VKDRKGDLGESEK--------AHQFLYDCGEAEAWMSEQELYM-----MQDERGKDEFST 4851
+K+R+ +L + ++ +F W+ E Y+ M +E G E
Sbjct: 2166 IKERELELQKEQRRQEENDKLRQEFAQHANAFHQWIQETRTYLLDGSCMVEESGTLESQL 2225
Query: 4852 KNQIKKHERLQS 4887
+ +KH+ +++
Sbjct: 2226 EATKRKHQEIRA 2237
Score = 222 bits (566), Expect = 9e-56
Identities = 205/908 (22%), Positives = 384/908 (41%), Gaps = 25/908 (2%)
Frame = +1
Query: 907 WINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRAN 1086
W+ A+ LN ++L+ V+ + + D+ +K E+ + F Q +
Sbjct: 1440 WMAAREAFLNTEDKGDSLDSVEALIKKHEDF---DKAINVQEEKIAALQAFADQLIAAGH 1496
Query: 1087 NQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRET 1266
+ + + D W+ L+ E+ L E Q +F+R + E
Sbjct: 1497 YAKGDISSRRNEVLD---RWRRLKAQMIEKRSKLGES--------QTLQQFSRDVDEIEA 1545
Query: 1267 WLTENQRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERXXXXXXXXXXXXXXNY--H 1440
W++E + S +++ D +++++ +KH+A E ++ A +R
Sbjct: 1546 WISEKLQTASDESY-KDPTNIQSKHQKHQAFEAELHANADRIRGVIDMGNSLIERGACAG 1604
Query: 1441 DQAKINERKENVXXXXXXXXXXXXARRVRLELSMAIQKIFHXXXXXXXXXXXIKSRLLSE 1620
+ + R + + +L+ + Q +++ L SE
Sbjct: 1605 SEDAVKARLAALADQWQFLVQKSAEKSQKLKEANKQQNFNTGIKDFDFWLSEVEALLASE 1664
Query: 1621 DLGAHLMDVEDLLQKHALLESDINIIGERVNNSIAQAQRFRNPDGPDGSGYKPVEPGTID 1800
D G L V +LL+KH LLE+DI+ +R+ + +QA D S K
Sbjct: 1665 DYGKDLASVNNLLKKHQLLEADISAHEDRLKDLNSQADSLMTSSAFDTSQVK-------- 1716
Query: 1801 ERSDVLQKRYKELLDLAAERKRRLEDNKRLCQFWWDVAELEHGIKEQEQVLSSTDTGRDI 1980
++ D + R++++ +AA R+ +L ++ RL QF+ D+ + E IKE++ ++ S D GRD+
Sbjct: 1717 DKRDTINGRFQKIKSMAASRRAKLNESHRLHQFFRDMDDEESWIKEKKLLVGSEDYGRDL 1776
Query: 1981 VTVSHLLAKHKNAENNLRDLEKYLDRLDVSGKELQDESIPGSDNIPPRLAEIRDYINKLK 2160
V +L KHK E L E + + +GK+L D++ G + I RLA+ ++ +LK
Sbjct: 1777 TGVQNLRKKHKRLEAELAAHEPAIQGVLDTGKKLSDDNTIGKEEIQQRLAQFVEHWKELK 1836
Query: 2161 ELSASRKERLAGGVEYYQFFTDADDVDRYLYDTLRVMSSEDVGKDEGTVQLLLKKHDDVH 2340
+L+A+R +RL +EY QF + ++ + ++ + + +++SED G +Q LLKKH+
Sbjct: 1837 QLAAARGQRLEESLEYQQFVANVEEEEAWINEKMTLVASEDYGDTLAAIQGLLKKHEAFE 1896
Query: 2341 DELQNFDQHIKVLHAKAESLPQEAREHPD-IRQRLDTTLKQKAELENLSQLRKQRLIDAL 2517
+ + + + L ++ H + I ++ + ++LE + RK +L +
Sbjct: 1897 TDFTVHKDRVNDVCTNGQDLIKKNNHHEENISSKMKGLNGKVSDLEKAAAQRKAKLDENS 1956
Query: 2518 SLYKLYSDADSVESWIDEKGKLLATLVPGRDIEEVEIMKHRFDTLEQDMKN-QEAKVTNV 2694
+ + AD VESWI EK L T GRD+ V+ + + +T + ++ Q+ + N+
Sbjct: 1957 AFLQFNWKADVVESWIGEKENSLKTDDYGRDLSSVQTLLTKQETFDAGLQAFQQEGIANI 2016
Query: 2695 NDLARQLLNVEHPNSDDILHRQNKLNARWAQL-RDMVDQKRNELERAHRLE-------TF 2850
L QLL +H S I R L RW+QL + +K+ LE TF
Sbjct: 2017 TALKDQLLAAKHVQSKAIEARHASLMKRWSQLLANSAARKKKLLEAQSHFRKVEDLFLTF 2076
Query: 2851 RIDCQETVTWIEDKTRVLEDSDALTNDLSGVMKLQRRLSMMERDLGAIQAKLDSLHKEAD 3030
+W E+ L D N L + L+ L + QA + L +
Sbjct: 2077 AKKASAFNSWFENAEEDLTDP-VRCNSLEEIKALREAHDAFRSSLSSAQADFNQLAELDR 2135
Query: 3031 DIERERPQEAQAIREDIKRIHQVWDILNKKVREHEAKLD------EAGDL--QRFLRDLD 3186
I+ R ++ + + W L K ++E E +L E D Q F + +
Sbjct: 2136 QIKSFRVASNPYTWFTMEALEETWRNLQKIIKERELELQKEQRRQEENDKLRQEFAQHAN 2195
Query: 3187 HFQAWLTATQRQVAS-----EEEPQSLAEAEQLLNQHAAIREEIDGYAEDYKKMRAMGDR 3351
F W+ T+ + EE ++ E +H +EI KK+ +G
Sbjct: 2196 AFHQWIQETRTYLLDGSCMVEESGTLESQLEATKRKH----QEIRAMRSQLKKIEDLGAA 2251
Query: 3352 VTQDQTDPQYMFLRQRLAGLQEGWEELQRMWDNRQHLLSQGLNLQMFLRDAKQAEVMLSQ 3531
+ ++ + GL + W++L ++ QH L Q + + ++A S
Sbjct: 2252 M-EEALILDNKYTEHSTVGLAQQWDQLDQLGMRMQHNLEQQIQARNTTGVTEEALKEFSM 2310
Query: 3532 QENYLAKD 3555
+ KD
Sbjct: 2311 MFKHFDKD 2318