Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F38A3_2
(3383 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|7511581|pir||T19121 probable protein-tyrosine-phosphatase (EC... 2266 0.0
gi|20871584|emb|CAA86842.3| Hypothetical protein C09D8.1a [Caeno... 2266 0.0
gi|20871585|emb|CAD31753.1| Hypothetical protein C09D8.1b [Caeno... 2266 0.0
gi|26985797|emb|CAD59171.1| Hypothetical protein C09D8.1c [Caeno... 2266 0.0
gi|25146572|ref|NP_741043.1| protein tyrosine phosphatase, LAR-l... 2254 0.0
gi|25146575|ref|NP_741044.1| protein tyrosine phosphatase, LAR-l... 2254 0.0
gi|39597360|emb|CAE59588.1| Hypothetical protein CBG02994 [Caeno... 2098 0.0
gi|31235464|ref|XP_319248.1| ENSANGP00000006103 [Anopheles gambi... 736 0.0
gi|20833032|ref|XP_131462.1| protein tyrosine phosphatase, recep... 726 0.0
gi|19263606|gb|AAH25145.1| Ptprd protein [Mus musculus] 726 0.0
gi|34869007|ref|XP_233065.2| similar to protein tyrosine phospha... 726 0.0
gi|4506309|ref|NP_002830.1| protein tyrosine phosphatase, recept... 726 0.0
gi|18860892|ref|NP_569076.1| protein tyrosine phosphatase, recep... 726 0.0
gi|18860894|ref|NP_569077.1| protein tyrosine phosphatase, recep... 726 0.0
gi|18860890|ref|NP_569075.1| protein tyrosine phosphatase, recep... 726 0.0
gi|35790|emb|CAA38068.1| protein-tyrosine phosphatase [Homo sapi... 726 0.0
gi|1079024|pir||S53089 protein-tyrosine-phosphatase (EC 3.1.3.48... 724 0.0
gi|7248657|gb|AAF43605.1| receptor protein tyrosine phosphatase ... 723 0.0
gi|19743925|ref|NP_570925.1| protein tyrosine phosphatase, recep... 719 0.0
gi|2118906|pir||I58148 protein-tyrosine-phosphatase (EC 3.1.3.48... 719 0.0
gi|19743921|ref|NP_570923.1| protein tyrosine phosphatase, recep... 719 0.0
gi|2118903|pir||A56493 leucocyte common antigen-related protein ... 719 0.0
gi|440973|gb|AAB28877.1| receptor protein tyrosine phosphatase-s... 719 0.0
gi|19743919|ref|NP_002841.2| protein tyrosine phosphatase, recep... 717 0.0
gi|4096822|gb|AAD09360.1| PTPsigma-(brain) [Homo sapiens] 717 0.0
gi|30851400|gb|AAH52462.1| Ptprs protein [Mus musculus] 714 0.0
gi|1109792|gb|AAC50299.1| protein tyrosine phosphatase sigma >gn... 714 0.0
gi|46048665|ref|NP_990738.1| protein-tyrosine phosphatase [Gallu... 712 0.0
gi|1083478|pir||C54689 protein-tyrosine-phosphatase (EC 3.1.3.48... 710 0.0
gi|1083477|pir||D54689 protein-tyrosine-phosphatase (EC 3.1.3.48... 710 0.0
gi|1083771|pir||A48758 protein-tyrosine-phosphatase (EC 3.1.3.48... 708 0.0
gi|47223076|emb|CAG07163.1| unnamed protein product [Tetraodon n... 708 0.0
gi|47219585|emb|CAG02291.1| unnamed protein product [Tetraodon n... 707 0.0
gi|310202|gb|AAA75407.1| receptor-linked protein tyrosine phosph... 706 0.0
gi|47213552|emb|CAF91826.1| unnamed protein product [Tetraodon n... 706 0.0
gi|3702284|gb|AAC62834.1| PTPsigma [AA 524- 1926] [Homo sapiens] 706 0.0
gi|9507011|ref|NP_062013.1| protein tyrosine phosphatase, recept... 706 0.0
gi|19743923|ref|NP_570924.1| protein tyrosine phosphatase, recep... 704 0.0
gi|1085568|pir||S46217 protein-tyrosine-phosphatase (EC 3.1.3.48... 703 0.0
gi|1407625|gb|AAC50567.1| PTPsigma 703 0.0
gi|15027042|emb|CAC44759.1| receptor protein-tyrosine phosphatas... 702 0.0
gi|7248661|gb|AAF43607.1| receptor protein tyrosine phosphatase ... 701 0.0
gi|1083485|pir||S50893 protein-tyrosine-phosphatase (EC 3.1.3.48... 701 0.0
gi|15292281|gb|AAK93409.1| LD45391p [Drosophila melanogaster] 699 0.0
gi|125977|sp|P16621|LAR_DROME Protein-tyrosine phosphatase Lar p... 699 0.0
gi|24585307|ref|NP_523604.2| CG10443-PA [Drosophila melanogaster... 699 0.0
gi|693993|emb|CAA58537.1| leucocyte common antigen-related prote... 696 0.0
gi|18860896|ref|NP_569707.1| protein tyrosine phosphatase, recep... 695 0.0
gi|4506311|ref|NP_002831.1| protein tyrosine phosphatase, recept... 695 0.0
gi|34870151|ref|XP_346749.1| hypothetical protein XP_346748 [Rat... 694 0.0
gi|205131|gb|AAA41510.1| leukocyte common antigen related protein 694 0.0
gi|249840|gb|AAB22251.1| LAR, leukocyte common antigen-related p... 694 0.0
gi|31873230|emb|CAD97607.1| hypothetical protein [Homo sapiens] 694 0.0
gi|28981412|gb|AAH48768.1| PTPRF protein [Homo sapiens] 693 0.0
gi|34980829|gb|AAH57166.1| Ptprf protein [Mus musculus] 693 0.0
gi|25092609|ref|NP_035348.1| protein tyrosine phosphatase, recep... 693 0.0
gi|1363186|pir||A57068 protein-tyrosine-phosphatase (EC 3.1.3.48... 693 0.0
gi|9507013|ref|NP_062122.1| protein tyrosine phosphatase, recept... 692 0.0
gi|7248659|gb|AAF43606.1| receptor protein tyrosine phosphatase ... 691 0.0
gi|18702313|ref|NP_035343.1| protein tyrosine phosphatase, recep... 689 0.0
gi|7766938|pdb|1LAR|A Chain A, Crystal Structure Of The Tandem P... 686 0.0
gi|47228368|emb|CAG07763.1| unnamed protein product [Tetraodon n... 685 0.0
gi|47211684|emb|CAF92848.1| unnamed protein product [Tetraodon n... 682 0.0
gi|452199|dbj|BAA03003.1| MPTPdelta [Mus musculus] 679 0.0
gi|7511703|pir||T31093 probable protein-tyrosine-phosphatase (EC... 676 0.0
gi|50761732|ref|XP_429156.1| PREDICTED: similar to protein tyros... 675 0.0
gi|7511704|pir||T30938 receptor tyrosine phosphatase - medicinal... 642 0.0
gi|15027040|emb|CAC44758.1| receptor protein-tyrosine phosphatas... 607 e-172
gi|7684260|dbj|BAA95173.1| amPTPR2A [Branchiostoma belcheri] 562 e-158
gi|7684309|dbj|BAA95176.1| hgPTPR2Aa [Eptatretus burgeri] 553 e-156
gi|7684339|dbj|BAA95191.1| ryPTPR2Ab [Potamotrygon motoro] 548 e-154
gi|7684333|dbj|BAA95188.1| ryPTPR2Aa [Potamotrygon motoro] 545 e-153
gi|7684343|dbj|BAA95193.1| ryPTPR2Ac [Potamotrygon motoro] 539 e-151
gi|7684313|dbj|BAA95178.1| hgPTPR2Ab [Eptatretus burgeri] 524 e-147
gi|392566|gb|AAC04306.1| LAR receptor-linked tyrosine phosphatas... 523 e-146
gi|38524399|dbj|BAD02400.1| protein tyrosine phosphatase a [Oryz... 508 e-142
gi|38524403|dbj|BAD02402.1| protein tyrosine phosphatase a [Oryz... 508 e-142
gi|18450369|ref|NP_543030.1| protein tyrosine phosphatase, recep... 505 e-141
gi|32067|emb|CAA37447.1| tyrosine phosphatase precursor [Homo sa... 505 e-141
gi|14193729|gb|AAK56109.1| protein tyrosin phosphatase receptor ... 505 e-141
gi|4506303|ref|NP_002827.1| protein tyrosine phosphatase, recept... 505 e-141
gi|126467|sp|P18433|PTRA_HUMAN Protein-tyrosine phosphatase alph... 505 e-141
gi|227294|prf||1701300A protein Tyr phosphatase 504 e-141
gi|32313|emb|CAA38662.1| protein-tyrosine phosphatase [Homo sapi... 497 e-139
gi|18859295|ref|NP_571963.1| protein tyrosine phosphatase, recep... 494 e-138
gi|285113|pir||JC1285 protein-tyrosine-phosphatase (EC 3.1.3.48)... 492 e-137
gi|6981446|ref|NP_036895.1| protein tyrosine phosphatase, recept... 492 e-137
gi|483922|gb|AAA17990.1| protein tyrosine phosphatase alpha 491 e-137
gi|6679557|ref|NP_033006.1| protein tyrosine phosphatase, recept... 485 e-135
gi|1127579|gb|AAC52331.1| epsilon tyrosine phosphatase cytoplasm... 481 e-134
gi|31543531|ref|NP_035342.2| protein tyrosine phosphatase, recep... 481 e-134
gi|2507226|sp|P49446|PTPE_MOUSE Protein-tyrosine phosphatase eps... 481 e-134
gi|1199933|dbj|BAA11927.1| protein tyrosine phosphatase epsilon ... 481 e-134
gi|7439344|pir||JC6132 protein-tyrosine-phosphatase (EC 3.1.3.48... 481 e-134
gi|5729993|ref|NP_006495.1| protein tyrosine phosphatase, recept... 480 e-133
gi|18860859|ref|NP_569119.1| protein tyrosine phosphatase, recep... 480 e-133
gi|34861151|ref|XP_341951.1| Protein tyrosine phosphatase, recep... 479 e-133
gi|15866730|emb|CAC86583.1| tyrosine phosphatase epsilon [Homo s... 479 e-133
gi|450583|gb|AAB04150.1| protein tyrosine phosphatase >gnl|BL_OR... 479 e-133
gi|2190301|dbj|BAA20333.1| protein tyrosine phosphatase epsilon ... 477 e-133
gi|38524401|dbj|BAD02401.1| protein tyrosine phosphatase e [Oryz... 476 e-132
gi|38524406|dbj|BAD02404.1| protein tyrosine phosphatase e [Oryz... 476 e-132
gi|131569|sp|P28827|PTPM_HUMAN Receptor-type protein-tyrosine ph... 468 e-130
gi|18860904|ref|NP_002836.2| protein tyrosine phosphatase, recep... 468 e-130
gi|2118904|pir||I56540 protein-tyrosine-phosphatase (EC 3.1.3.48... 466 e-129
gi|18860902|ref|NP_002835.2| protein tyrosine phosphatase, recep... 464 e-129
gi|28629201|gb|AAO49502.1| mutant receptor type protein tyrosine... 464 e-129
gi|2499753|sp|Q15262|PTPK_HUMAN Receptor-type protein-tyrosine p... 463 e-128
gi|1479976|gb|AAC37599.1| protein tyrosine phosphatase [Homo sap... 463 e-128
gi|6679563|ref|NP_033010.1| protein tyrosine phosphatase, recept... 463 e-128
gi|228097|prf||1717216B receptor-like Tyr phosphatase 463 e-128
gi|47222311|emb|CAG05060.1| unnamed protein product [Tetraodon n... 459 e-127
gi|30353785|gb|AAH51651.1| PTPRM protein [Homo sapiens] 459 e-127
gi|27529712|dbj|BAA22952.2| KIAA0283 [Homo sapiens] 459 e-127
gi|48762922|ref|NP_573400.2| protein tyrosine phosphatase, recep... 459 e-127
gi|48762924|ref|NP_008981.3| protein tyrosine phosphatase, recep... 458 e-127
gi|6679561|ref|NP_033009.1| protein tyrosine phosphatase, recept... 458 e-127
gi|33112429|sp|Q99M80|PTPT_MOUSE Receptor-type protein-tyrosine ... 457 e-127
gi|13378308|gb|AAK18742.1| brain RPTPmam4 isoform II [Mus musculus] 457 e-127
gi|7684321|dbj|BAA95182.1| hgPTPR2Ac [Eptatretus burgeri] 457 e-127
gi|50743033|ref|XP_419748.1| PREDICTED: similar to protein tyros... 456 e-126
gi|10946856|ref|NP_067439.1| protein tyrosine phosphatase, recep... 456 e-126
gi|33112420|sp|O14522|PTPT_HUMAN Receptor-type protein-tyrosine ... 456 e-126
gi|47210609|emb|CAF89865.1| unnamed protein product [Tetraodon n... 454 e-126
gi|9049512|gb|AAF82401.1| receptor-like protein tyrosine phospha... 454 e-126
gi|7439347|pir||JC6312 protein-tyrosine-phosphatase (EC 3.1.3.48... 452 e-125
gi|47214005|emb|CAG01518.1| unnamed protein product [Tetraodon n... 452 e-125
gi|7525122|gb|AAD34158.4| receptor protein tyrosine phosphatase-... 452 e-125
gi|21724185|gb|AAM28342.1| LAR [Culicoides sonorensis] 452 e-125
gi|1083772|pir||B48758 protein-tyrosine-phosphatase (EC 3.1.3.48... 448 e-124
gi|310204|gb|AAA50568.1| receptor-linked protein tyrosine phosph... 446 e-123
gi|13378310|gb|AAK18743.1| brain RPTPmam4 isoform III [Mus muscu... 444 e-123
gi|50747441|ref|XP_426359.1| PREDICTED: protein-tyrosine-phospha... 436 e-120
gi|50736633|ref|XP_419135.1| PREDICTED: similar to Receptor-type... 434 e-120
gi|50749981|ref|XP_421821.1| PREDICTED: similar to Protein-tyros... 429 e-118
gi|227796|prf||1711408A protein Tyr phosphatase LAR 419 e-115
gi|19743935|ref|NP_005695.2| protein tyrosine phosphatase, recep... 417 e-115
gi|7439345|pir||JC5290 protein-tyrosine-phosphatase (EC 3.1.3.48... 416 e-114
gi|45383181|ref|NP_989823.1| receptor tyrosine phosphatase [Gall... 412 e-113
gi|7684349|dbj|BAA95196.1| ryPTPR4b [Potamotrygon motoro] 408 e-112
gi|47214899|emb|CAG01030.1| unnamed protein product [Tetraodon n... 407 e-112
gi|50539668|ref|NP_001002299.1| protein tyrosine phosphatase, re... 405 e-111
gi|7684315|dbj|BAA95179.1| hgPTPR4 [Eptatretus burgeri] 404 e-111
gi|1518672|gb|AAB07074.1| receptor protein tyrosine phosphatase psi 404 e-110
gi|19743933|ref|NP_573439.1| protein tyrosine phosphatase, recep... 403 e-110
gi|18860898|ref|NP_002832.2| protein tyrosine phosphatase, recep... 402 e-110
gi|477137|pir||A48148 protein-tyrosine-phosphatase (EC 3.1.3.48)... 402 e-110
gi|6679559|ref|NP_033007.1| protein tyrosine phosphatase, recept... 402 e-110
gi|2499758|sp|Q92729|PTPU_HUMAN Receptor-type protein-tyrosine p... 402 e-110
gi|1263069|gb|AAC50439.1| receptor tyrosine phosphatase gamma >g... 401 e-110
gi|19743931|ref|NP_573438.1| protein tyrosine phosphatase, recep... 400 e-110
gi|34871761|ref|XP_342931.1| protein tyrosine phosphatase, recep... 400 e-109
gi|1890660|gb|AAC51938.1| protein tyrosine phosphatase receptor ... 399 e-109
gi|7439346|pir||S72441 protein-tyrosine-phosphatase (EC 3.1.3.48... 399 e-109
gi|31206259|ref|XP_312081.1| ENSANGP00000016184 [Anopheles gambi... 399 e-109
gi|548625|sp|P35832|PTP9_DROME Protein-tyrosine phosphatase 99A ... 397 e-108
gi|17136638|ref|NP_476816.1| CG2005-PB [Drosophila melanogaster]... 396 e-108
gi|24651039|ref|NP_733288.1| CG2005-PA [Drosophila melanogaster]... 396 e-108
gi|157300|gb|AAA28486.1| protein-tyrosine phosphatase 396 e-108
gi|157298|gb|AAA28485.1| receptor-linked protein tyrosine phosph... 396 e-108
gi|45553601|ref|NP_996302.1| CG2005-PC [Drosophila melanogaster]... 396 e-108
gi|6755246|ref|NP_035344.1| protein tyrosine phosphatase, recept... 395 e-108
gi|2627027|dbj|BAA23475.1| Ftp-1 [Mus musculus] 395 e-108
gi|35794|emb|CAA38067.1| protein-tyrosine phosphatase [Homo sapi... 395 e-108
gi|45383516|ref|NP_989645.1| protein tyrosine phosphatase, recep... 395 e-108
gi|3355583|emb|CAA19666.1| dJ707K17.1 (Protein tyrosine phosphat... 394 e-108
gi|47216590|emb|CAG00625.1| unnamed protein product [Tetraodon n... 390 e-106
gi|7684256|dbj|BAA95171.1| amPTPR4c [Branchiostoma belcheri] 388 e-106
gi|5572699|dbj|BAA82558.1| sPTPR4 [Ephydatia fluviatilis] 386 e-105
gi|13276131|emb|CAC33882.1| receptor protein tyrosine phosphatas... 385 e-105
gi|8885504|dbj|BAA97445.1| receptor-type protein tyrosine phosph... 385 e-105
gi|45382183|ref|NP_990762.1| phosphotyrosyl phosphatase [Gallus ... 385 e-105
gi|300182|gb|AAB26530.1| receptor-type protein tyrosine phosphat... 384 e-105
gi|29789369|ref|NP_599183.1| protein tyrosine phosphatase, recep... 380 e-104
gi|4506329|ref|NP_002842.1| protein tyrosine phosphatase, recept... 380 e-104
gi|25281969|gb|AAN72430.1| receptor-like protein tyrosine phosph... 380 e-104
gi|6094682|gb|AAF03527.1| receptor-type protein tyrosine phospha... 380 e-104
gi|7684252|dbj|BAA95169.1| amPTPR4a [Branchiostoma belcheri] 380 e-103
gi|47682858|gb|AAH70850.1| MGC84589 protein [Xenopus laevis] 380 e-103
gi|34858623|ref|XP_346676.1| hypothetical protein XP_346675 [Rat... 380 e-103
gi|6981448|ref|NP_037212.1| protein tyrosine phosphatase, recept... 380 e-103
gi|34854925|ref|XP_346696.1| hypothetical protein XP_346695 [Rat... 380 e-103
gi|7684337|dbj|BAA95190.1| ryPTPR4a [Potamotrygon motoro] 379 e-103
gi|45383331|ref|NP_989748.1| protein tyrosine phosphatase, recep... 373 e-101
gi|7684254|dbj|BAA95170.1| amPTPR4b [Branchiostoma belcheri] 369 e-100
gi|23954318|emb|CAD54117.1| dJ480J14.2.1 (protein tyrosine phosp... 366 2e-99
gi|11275231|pir||T43148 probable protein-tyrosine-phosphatase (E... 366 2e-99
gi|41399291|gb|AAS06903.1| CD45 [Aotus vociferans] 364 9e-99
gi|31207837|ref|XP_312885.1| ENSANGP00000003247 [Anopheles gambi... 364 9e-99
gi|47220844|emb|CAG00051.1| unnamed protein product [Tetraodon n... 363 1e-98
gi|41399289|gb|AAS06902.1| CD45 [Aotus nancymaae] 363 1e-98
gi|10999057|gb|AAD15273.2| T200 leukocyte common antigen precurs... 363 2e-98
gi|18641347|ref|NP_002829.2| protein tyrosine phosphatase, recep... 363 2e-98
gi|18641362|ref|NP_563578.1| protein tyrosine phosphatase, recep... 363 2e-98
gi|18641364|ref|NP_563579.1| protein tyrosine phosphatase, recep... 363 2e-98
gi|539627|pir||A46546 leukocyte common antigen long splice form ... 362 3e-98
gi|34281|emb|CAA68669.1| unnamed protein product [Homo sapiens] 362 3e-98
gi|24663403|ref|NP_524048.2| CG10975-PA [Drosophila melanogaster... 356 2e-96
gi|28574507|ref|NP_788502.1| CG10975-PB [Drosophila melanogaster... 356 2e-96
gi|118913|sp|P16620|PTP6_DROME Protein-tyrosine phosphatase DPTP... 356 2e-96
gi|45479860|gb|AAS06901.1| CD45 [Aotus nigriceps] 356 2e-96
gi|8919952|emb|CAB96212.1| CD45 [Takifugu rubripes] 352 3e-95
gi|90254|pir||A28334 protein-tyrosine-phosphatase (EC 3.1.3.48) ... 352 3e-95
gi|198917|gb|AAA39459.1| lymphocyte common antigen 352 3e-95
gi|8919950|emb|CAB96211.1| CD45 [Takifugu rubripes] 352 3e-95
gi|116008|sp|P04157|CD45_RAT Leukocyte common antigen variant 4 ... 352 5e-95
gi|56562|emb|CAA68275.1| L-CA variant 1 [Rattus norvegicus] 352 5e-95
gi|56560|emb|CAA68273.1| L-CA variant 3 [Rattus norvegicus] 352 5e-95
gi|7106471|dbj|BAA92179.1| CD45 [Cyprinus carpio] 352 5e-95
gi|29789375|ref|NP_612516.1| protein tyrosine phosphatase, recep... 352 5e-95
gi|11382546|pir||TDRTLT leukocyte common antigen precursor, spli... 352 5e-95
gi|56561|emb|CAA68274.1| L-CA variant 2 [Rattus norvegicus] 352 5e-95
gi|5572701|dbj|BAA82559.1| sPTPR2B [Ephydatia fluviatilis] 351 8e-95
gi|6755244|ref|NP_035340.1| protein tyrosine phosphatase, recept... 346 2e-93
gi|22022293|dbj|BAC06502.1| CD45 [Eptatretus stoutii] 346 2e-93
gi|22022295|dbj|BAC06503.1| CD45 [Eptatretus stoutii] 346 2e-93
gi|22022291|dbj|BAC06501.1| CD45 [Eptatretus stoutii] 346 2e-93
gi|22022307|dbj|BAC06504.1| CD45 [Eptatretus stoutii] 345 3e-93
gi|22022289|dbj|BAC06500.1| CD45 [Eptatretus stoutii] 342 4e-92
gi|38081981|ref|XP_205540.2| similar to protein tyrosine phospha... 340 1e-91
gi|5738203|gb|AAD50295.1| receptor protein tyrosine phosphatase ... 338 4e-91
gi|24935301|gb|AAN64298.1| CD45 protein tyrosine phosphatase rec... 338 5e-91
gi|34484430|gb|AAQ72837.1| CD45 [Ictalurus punctatus] 337 2e-90
gi|7684250|dbj|BAA95168.1| amPTP10 [Branchiostoma belcheri] 335 4e-90
gi|47223052|emb|CAG07139.1| unnamed protein product [Tetraodon n... 329 3e-88
gi|21955962|dbj|BAC06424.1| protein tyrosine phosphatase e [Oryz... 328 4e-88
gi|47204449|emb|CAG04747.1| unnamed protein product [Tetraodon n... 317 1e-84
gi|7684345|dbj|BAA95194.1| ryPTPR2B [Potamotrygon motoro] 315 6e-84
gi|930104|emb|CAA38070.1| protein-tyrosine phosphatase [Homo sap... 314 1e-83
gi|47229749|emb|CAG06945.1| unnamed protein product [Tetraodon n... 314 1e-83
gi|47206263|emb|CAF91063.1| unnamed protein product [Tetraodon n... 311 5e-83
gi|47212380|emb|CAF91392.1| unnamed protein product [Tetraodon n... 310 1e-82
gi|3114491|pdb|1RPM|A Chain A, Human Receptor Protein Tyrosine P... 310 1e-82
gi|48094922|ref|XP_392208.1| similar to receptor-linked protein ... 308 4e-82
gi|47218237|emb|CAF96274.1| unnamed protein product [Tetraodon n... 308 7e-82
gi|19171239|emb|CAD23182.1| tyrosine phosphatase epsilon PD1 [Ho... 296 2e-78
gi|387402|gb|AAA39418.1| leukocyte common antigen 295 5e-78
gi|34878223|ref|XP_343641.1| protein tyrosine phosphatase, recep... 294 1e-77
gi|48097821|ref|XP_393897.1| similar to protein tyrosine phospha... 290 2e-76
gi|25281971|gb|AAN72431.1| receptor-like protein tyrosine phosph... 290 2e-76
gi|7684258|dbj|BAA95172.1| amPTPR5 [Branchiostoma belcheri] 288 5e-76
gi|1519396|gb|AAB42210.1| receptor type protein tyrosine phospha... 286 3e-75
gi|7684351|dbj|BAA95197.1| ryPTPR5b [Potamotrygon motoro] 280 2e-73
gi|11275230|pir||T42522 protein-tyrosine-phosphatase (EC 3.1.3.4... 279 3e-73
gi|25154084|ref|NP_495041.2| encoding in order receptor tyrosine... 279 3e-73
gi|24418260|gb|AAN60516.1| Clear protein 1, isoform b [Caenorhab... 279 3e-73
gi|2098414|pdb|1YFO|A Chain A, Receptor Protein Tyrosine Phospha... 277 1e-72
gi|7684311|dbj|BAA95177.1| hgPTPR5a [Eptatretus burgeri] 273 2e-71
gi|7684347|dbj|BAA95195.1| ryPTPR5a [Potamotrygon motoro] 272 5e-71
gi|26343963|dbj|BAC35638.1| unnamed protein product [Mus musculus] 271 8e-71
gi|7504409|pir||T30111 hypothetical protein F56D1.4 - Caenorhabd... 269 3e-70
gi|39596883|emb|CAE59110.1| Hypothetical protein CBG02405 [Caeno... 267 1e-69
gi|50761278|ref|XP_419254.1| PREDICTED: similar to protein-tyros... 265 6e-69
gi|112238|pir||A40169 protein-tyrosine-phosphatase (EC 3.1.3.48)... 259 2e-67
gi|48117151|ref|XP_396411.1| similar to ENSANGP00000011584 [Apis... 254 8e-66
gi|19921474|ref|NP_609872.1| CG7180-PA [Drosophila melanogaster]... 252 5e-65
gi|31223985|ref|XP_317380.1| ENSANGP00000011584 [Anopheles gambi... 248 7e-64
gi|34328115|ref|NP_031981.2| protein tyrosine phosphatase, recep... 244 1e-62
gi|3183134|sp|P70289|PTPV_MOUSE Receptor-type protein-tyrosine p... 244 1e-62
gi|45382907|ref|NP_989952.1| supporting-cell antigen [Gallus gal... 240 1e-61
gi|38090755|ref|XP_137234.3| similar to protein tyrosine phospha... 238 6e-61
gi|12621078|ref|NP_075214.1| protein tyrosine phosphatase, recep... 237 1e-60
gi|46402289|ref|NP_997153.1| protein tyrosine phosphatase, recep... 236 2e-60
gi|45383866|ref|NP_989453.1| protein tyrosine phosphatase, recep... 235 5e-60
gi|50728376|ref|XP_416114.1| PREDICTED: similar to protein tyros... 235 6e-60
gi|19424294|ref|NP_598276.1| brain-enriched membrane-associated ... 235 6e-60
gi|4506313|ref|NP_002833.1| protein tyrosine phosphatase, recept... 234 1e-59
gi|2144715|pir||I38670 protein-tyrosine-phosphatase (EC 3.1.3.48... 234 1e-59
gi|1685075|gb|AAB36687.1| density enhanced phosphatase-1 234 1e-59
gi|18860900|ref|NP_002834.2| protein tyrosine phosphatase, recep... 234 1e-59
gi|633073|dbj|BAA07035.1| protein-tyrosine phosphatase [Homo sap... 234 1e-59
gi|17541230|ref|NP_501863.1| protein tyrosine phosphatase, recep... 234 1e-59
gi|21634739|gb|AAM69432.1| protein tyrosine phosphatase receptor... 234 1e-59
gi|9652147|gb|AAF91411.1| transmembrane-type protein tyrosine ph... 233 2e-59
gi|22128621|ref|NP_033008.1| protein tyrosine phosphatase, recep... 232 4e-59
gi|21631865|gb|AAK98640.1| PTPRJ [Mus musculus] 232 4e-59
gi|682753|dbj|BAA08386.1| protein tyrosine phosphatase [Mus musc... 232 4e-59
gi|8394112|ref|NP_058965.1| protein tyrosine phosphatase, recept... 232 4e-59
gi|14861868|ref|NP_149090.1| Osteotesticular phosphatase; protei... 231 7e-59
gi|1083770|pir||A55148 protein-tyrosine-phosphatase (EC 3.1.3.48... 231 7e-59
gi|23268287|gb|AAN11409.1| protein tyrosine phosphatase receptor... 231 1e-58
gi|39585712|emb|CAE59914.1| Hypothetical protein CBG03399 [Caeno... 230 2e-58
gi|34367936|emb|CAE46198.1| hypothetical protein [Homo sapiens] 230 2e-58
gi|18491010|ref|NP_002828.2| protein tyrosine phosphatase, recep... 229 3e-58
gi|126469|sp|P23467|PTPB_HUMAN Protein-tyrosine phosphatase beta... 229 3e-58
gi|24641350|ref|NP_511127.2| CG1817-PC [Drosophila melanogaster]... 229 3e-58
gi|28416331|gb|AAO42638.1| RE52018p [Drosophila melanogaster] 229 3e-58
gi|20455509|sp|P35992|PTP1_DROME Protein-tyrosine phosphatase 10... 229 3e-58
gi|157296|gb|AAA28484.1| protein-tyrosine phosphatase 229 3e-58
gi|24641348|ref|NP_727544.1| CG1817-PB [Drosophila melanogaster]... 229 3e-58
gi|50728336|ref|XP_416095.1| PREDICTED: similar to Protein-tyros... 229 3e-58
gi|158645|gb|AAA28952.1| receptor-linked protein tyrosine phosph... 229 3e-58
gi|47214726|emb|CAG01079.1| unnamed protein product [Tetraodon n... 229 3e-58
gi|103342|pir||D41214 protein-tyrosine-phosphatase (EC 3.1.3.48)... 229 3e-58
gi|33112422|sp|Q16827|PTPO_HUMAN Receptor-type protein-tyrosine ... 229 3e-58
gi|103341|pir||C41214 protein-tyrosine-phosphatase (EC 3.1.3.48)... 229 3e-58
gi|1321658|dbj|BAA08252.1| brain-enriched membrane-associated pr... 228 6e-58
gi|8394227|ref|NP_059032.1| receptor-type protein tyrosine phosp... 228 6e-58
gi|13677214|ref|NP_109592.1| receptor-type protein tyrosine phos... 228 6e-58
gi|13677218|ref|NP_109594.1| receptor-type protein tyrosine phos... 228 6e-58
gi|13677216|ref|NP_109593.1| receptor-type protein tyrosine phos... 228 6e-58
gi|4506323|ref|NP_002839.1| receptor-type protein tyrosine phosp... 228 6e-58
gi|7958608|gb|AAF70856.1| glomerular epithelial protein 1 precur... 228 8e-58
gi|47059069|ref|NP_035346.2| protein tyrosine phosphatase, recep... 228 8e-58
gi|627804|pir||A53661 protein-tyrosine-phosphatase (EC 3.1.3.48)... 228 8e-58
gi|2137014|pir||S68250 protein-tyrosine-phosphatase (EC 3.1.3.48... 228 8e-58
gi|30704669|gb|AAH51976.1| Ptpro protein [Mus musculus] 228 1e-57
gi|24639790|ref|NP_525076.2| CG6899-PA [Drosophila melanogaster]... 228 1e-57
gi|8886021|gb|AAF80346.1| receptor-type protein tyrosine phospha... 228 1e-57
gi|38969708|gb|AAH63258.1| Ptpro protein [Mus musculus] 228 1e-57
gi|24639792|ref|NP_726967.1| CG6899-PB [Drosophila melanogaster]... 228 1e-57
gi|48098669|ref|XP_394130.1| similar to ENSANGP00000013354 [Apis... 226 2e-57
gi|1063642|gb|AAC52312.1| protein tyrosine phosphatase phi, shor... 226 2e-57
gi|39597557|emb|CAE59787.1| Hypothetical protein CBG03240 [Caeno... 226 3e-57
gi|2118909|pir||I49372 protein-tyrosine-phosphatase (EC 3.1.3.48... 226 3e-57
gi|433182|gb|AAA76834.1| receptor protein tyrosine phosphatase 226 3e-57
gi|1362625|pir||A49502 protein-tyrosine-phosphatase (EC 3.1.3.48... 226 3e-57
gi|1362626|pir||B49502 protein-tyrosine-phosphatase (EC 3.1.3.48... 226 3e-57
gi|23618914|ref|NP_084204.1| protein tyrosine phosphatase, recep... 226 4e-57
gi|21328284|gb|AAM48511.1| CD45 phosphatase [Aotus vociferans] 225 6e-57
gi|110068|pir||S17671 protein-tyrosine-phosphatase (EC 3.1.3.48)... 224 8e-57
gi|25294241|pir||JC7503 protein-tyrosine-phosphatase (EC 3.1.3.4... 224 8e-57
gi|48096511|ref|XP_394701.1| similar to CG32697-PA [Apis mellifera] 224 8e-57
gi|31243219|ref|XP_322055.1| ENSANGP00000004166 [Anopheles gambi... 224 1e-56
gi|17534045|ref|NP_495925.1| protein tyrosine phosphatase 10D (2... 224 1e-56
gi|28436889|gb|AAH47086.1| Ptprb protein [Mus musculus] 224 1e-56
gi|41149682|ref|XP_370699.1| similar to protein tyrosine phospha... 224 1e-56
gi|34864869|ref|XP_235156.2| similar to vascular endothelial pro... 224 1e-56
gi|1063644|gb|AAC52313.1| protein tyrosine phosphatase phi, inse... 223 3e-56
gi|24640860|ref|NP_727357.1| CG32697-PB [Drosophila melanogaster... 221 9e-56
gi|24640857|ref|NP_727356.1| CG32697-PC [Drosophila melanogaster... 221 9e-56
gi|24640862|ref|NP_727358.1| CG32697-PD [Drosophila melanogaster... 221 9e-56
gi|18858107|ref|NP_572576.1| CG32697-PA [Drosophila melanogaster... 221 9e-56
gi|47215255|emb|CAG01147.1| unnamed protein product [Tetraodon n... 218 1e-54
gi|34810523|pdb|1P15|A Chain A, Crystal Structure Of The D2 Doma... 217 1e-54
gi|20151415|gb|AAM11067.1| GH15539p [Drosophila melanogaster] 216 3e-54
gi|50507486|emb|CAH04723.1| Hypothetical protein T13H5.1b [Caeno... 209 4e-52
gi|26335575|dbj|BAC31488.1| unnamed protein product [Mus musculus] 209 4e-52
gi|50507487|emb|CAA91417.3| Hypothetical protein T13H5.1a [Caeno... 209 4e-52
gi|33300353|emb|CAA91422.2| Hypothetical protein T13H5.1 [Caenor... 209 4e-52
gi|47207147|emb|CAF94630.1| unnamed protein product [Tetraodon n... 209 5e-52
gi|47209429|emb|CAF95064.1| unnamed protein product [Tetraodon n... 208 8e-52
gi|16758788|ref|NP_446360.1| protein tyrosine phosphatase, non-r... 206 4e-51
gi|4097668|gb|AAD00151.1| SH2 phosphatase 1 [Mus musculus] 205 5e-51
gi|7305133|ref|NP_038573.1| hemopoietic cell phosphatase [Mus mu... 205 5e-51
gi|21903454|sp|P29351|PTN6_MOUSE Protein-tyrosine phosphatase, n... 205 5e-51
gi|15215088|gb|AAH12660.1| Hemopoietic cell phosphatase [Mus mus... 205 5e-51
gi|2289909|gb|AAC36008.1| PTPN6 [Mus musculus] 205 5e-51
gi|47212278|emb|CAF89510.1| unnamed protein product [Tetraodon n... 204 1e-50
gi|18104993|ref|NP_536859.1| protein tyrosine phosphatase, non-r... 202 3e-50
gi|5825608|gb|AAD53317.1| 70 kDa SHP-1L protein [Homo sapiens] 202 3e-50
gi|2547230|gb|AAB81279.1| CD45 [Xenopus laevis] 202 4e-50
gi|557899|gb|AAA82879.1| protein tyrosine phosphatase 1C 202 4e-50
gi|1732418|gb|AAB51322.1| protein tyrosine phosphatase 1C [Homo ... 202 4e-50
gi|30584457|gb|AAP36481.1| Homo sapiens protein tyrosine phospha... 202 4e-50
gi|338080|gb|AAA36610.1| tyrosine phosphatase 202 4e-50
gi|557900|gb|AAA82880.1| protein tyrosine phosphatase 1C 202 4e-50
gi|18104989|ref|NP_002822.2| protein tyrosine phosphatase, non-r... 202 4e-50
gi|18104991|ref|NP_536858.1| protein tyrosine phosphatase, non-r... 202 4e-50
gi|50752652|ref|XP_413696.1| PREDICTED: similar to Protein-tyros... 201 1e-49
gi|5822080|pdb|1GWZ| Crystal Structure Of The Catalytic Domain ... 201 1e-49
gi|47224142|emb|CAG13062.1| unnamed protein product [Tetraodon n... 200 2e-49
gi|50762246|ref|XP_424987.1| PREDICTED: similar to protein tyros... 199 3e-49
gi|34863475|ref|XP_236280.2| similar to Protein-tyrosine phospha... 199 5e-49
gi|31418511|gb|AAH53017.1| Unknown (protein for MGC:62214) [Mus ... 198 6e-49
gi|47940438|gb|AAH71574.1| PTPN9 protein [Homo sapiens] 198 8e-49
gi|4506301|ref|NP_002824.1| protein tyrosine phosphatase, non-re... 197 1e-48
gi|13399465|pdb|1FPR|A Chain A, Crystal Structure Of The Complex... 197 2e-48
gi|627275|pir||B53978 protein-tyrosine-phosphatase (EC 3.1.3.48)... 196 4e-48
gi|50414825|gb|AAH77326.1| LOC397709 protein [Xenopus laevis] 195 5e-48
gi|47216120|emb|CAG11188.1| unnamed protein product [Tetraodon n... 194 9e-48
gi|7684319|dbj|BAA95181.1| hgPTPR2B [Eptatretus burgeri] 194 1e-47
gi|39587160|emb|CAE57628.1| Hypothetical protein CBG00613 [Caeno... 194 1e-47
gi|4519425|dbj|BAA02740.2| protein-tyrosine phosphatase [Homo sa... 194 2e-47
gi|9790181|ref|NP_062625.1| protein tyrosine phosphatase, non-re... 194 2e-47
gi|47225918|emb|CAF98398.1| unnamed protein product [Tetraodon n... 193 2e-47
gi|20177095|gb|AAM12251.1| GH22607p [Drosophila melanogaster] 193 3e-47
gi|50759255|ref|XP_417590.1| PREDICTED: similar to Hypothetical ... 193 3e-47
gi|31240897|ref|XP_320862.1| ENSANGP00000019140 [Anopheles gambi... 193 3e-47
gi|17536251|ref|NP_495794.1| protein tyrosine phosphatase recept... 192 4e-47
gi|47221567|emb|CAF97832.1| unnamed protein product [Tetraodon n... 192 4e-47
gi|27696700|gb|AAH43621.1| MGC52584 protein [Xenopus laevis] 192 4e-47
gi|41054133|ref|NP_956140.1| protein tyrosine phosphatase, non-r... 192 5e-47
gi|47717352|gb|AAR97566.1| frizzled-8 associated multidomain pro... 191 8e-47
gi|31207081|ref|XP_312507.1| ENSANGP00000001164 [Anopheles gambi... 191 8e-47
gi|33356177|ref|NP_002825.3| protein tyrosine phosphatase, non-r... 191 1e-46
gi|45384450|ref|NP_990299.1| cSH-PTP2 [Gallus gallus] >gnl|BL_OR... 191 1e-46
gi|627274|pir||A53978 protein-tyrosine-phosphatase (EC 3.1.3.48)... 191 1e-46
gi|41053929|ref|NP_956254.1| protein tyrosine phosphatase, non-r... 190 2e-46
gi|46849981|gb|AAT02413.1| protein tyrosine phosphatase non-rece... 190 2e-46
gi|37590688|gb|AAH59278.1| Ptpn11 protein [Mus musculus] 189 3e-46
gi|49256084|gb|AAH74171.1| Unknown (protein for MGC:81984) [Xeno... 189 4e-46
gi|6981444|ref|NP_037220.1| protein tyrosine phosphatase, non-re... 189 4e-46
gi|3123258|sp|P41499|PTNB_RAT Protein-tyrosine phosphatase, non-... 189 4e-46
gi|628027|pir||A53593 protein-tyrosine-phosphatase (EC 3.1.3.48)... 188 9e-46
gi|34876034|ref|XP_213997.2| similar to protein Tyr phosphatase ... 187 1e-45
gi|50729470|ref|XP_425519.1| PREDICTED: similar to protein tyros... 187 1e-45
gi|464495|sp|P35235|PTNB_MOUSE Protein-tyrosine phosphatase, non... 187 1e-45
gi|6755228|ref|NP_035332.1| protein tyrosine phosphatase, non-re... 187 1e-45
gi|4558223|pdb|2SHP|A Chain A, Tyrosine Phosphatase Shp-2 >gnl|B... 187 2e-45
gi|7684353|dbj|BAA95198.1| ryPTPN6b [Potamotrygon motoro] 187 2e-45
gi|34879411|ref|XP_341110.1| similar to testis-enriched protein ... 187 2e-45
gi|5572703|dbj|BAA82560.1| sPTPR5 [Ephydatia fluviatilis] 187 2e-45
gi|106895|pir||JH0692 protein-tyrosine-phosphatase (EC 3.1.3.48)... 186 3e-45
gi|50417772|gb|AAH78054.1| MGC83117 protein [Xenopus laevis] 186 3e-45
gi|280853|pir||A60345 protein-tyrosine-phosphatase (EC 3.1.3.48)... 186 3e-45
gi|4506291|ref|NP_002819.1| protein tyrosine phosphatase, non-re... 186 3e-45
gi|88523|pir||A33899 protein-tyrosine-phosphatase (EC 3.1.3.48),... 186 3e-45
gi|21465994|pdb|1L8K|A Chain A, T Cell Protein-Tyrosine Phosphat... 186 3e-45
gi|47123868|gb|AAH70687.1| MGC83117 protein [Xenopus laevis] 186 3e-45
gi|18104980|ref|NP_536347.1| protein tyrosine phosphatase, non-r... 186 3e-45
gi|18104982|ref|NP_536348.1| protein tyrosine phosphatase, non-r... 186 3e-45
gi|18375658|ref|NP_002823.2| protein tyrosine phosphatase, non-r... 185 6e-45
gi|18375660|ref|NP_542155.1| protein tyrosine phosphatase, non-r... 185 6e-45
gi|17554412|ref|NP_497733.1| protein tyrosine phosphatase (68.8 ... 185 7e-45
gi|26339848|dbj|BAC33587.1| unnamed protein product [Mus musculus] 185 7e-45
gi|45382391|ref|NP_990206.1| non-receptor protein tyrosine phosp... 185 7e-45
gi|6755232|ref|NP_035334.1| protein tyrosine phosphatase, non-re... 185 7e-45
gi|17554410|ref|NP_497732.1| protein tyrosine phosphatase (115.1... 185 7e-45
gi|25151513|ref|NP_741112.1| protein tyrosine phosphatase (ptp-1... 185 7e-45
gi|28892997|ref|NP_796055.1| RIKEN cDNA C920001D21 gene [Mus mus... 185 7e-45
gi|47215565|emb|CAG10736.1| unnamed protein product [Tetraodon n... 184 1e-44
gi|4506295|ref|NP_002821.1| protein tyrosine phosphatase, non-re... 184 1e-44
gi|187228|gb|AAA59531.1| protein tyrosine phosphatase 184 1e-44
gi|45477181|sp|Q64512|PTND_MOUSE Protein tyrosine phosphatase, n... 184 2e-44
gi|18652302|gb|AAL77056.1| SH2 phosphatase 1 [Rattus norvegicus] 184 2e-44
gi|515031|emb|CAA56563.1| protein-tyrosine-phosphatase [Homo sap... 184 2e-44
gi|5453992|ref|NP_006255.1| protein tyrosine phosphatase, non-re... 184 2e-44
gi|18375646|ref|NP_542414.1| protein tyrosine phosphatase, non-r... 184 2e-44
gi|517125|dbj|BAA05885.1| protein tyrosine phosphatase DPZPTP [M... 184 2e-44
gi|1486367|emb|CAA56124.1| tyrosine phosphatase [Homo sapiens] 184 2e-44
gi|9910518|ref|NP_064317.1| protein tyrosine phosphatase, non-re... 184 2e-44
gi|627585|pir||A54971 protein-tyrosine-phosphatase (EC 3.1.3.48)... 184 2e-44
gi|18375650|ref|NP_542416.1| protein tyrosine phosphatase, non-r... 184 2e-44
gi|18375648|ref|NP_542415.1| protein tyrosine phosphatase, non-r... 184 2e-44
gi|16758896|ref|NP_446442.1| protein tyrosine phosphatase, non-r... 183 2e-44
gi|7435158|pir||S71625 protein-tyrosine-phosphatase (EC 3.1.3.48... 183 2e-44
gi|1232104|dbj|BAA12158.1| protein tyrosine phosphatase [Mus mus... 183 2e-44
gi|1094005|prf||2105234A protein Tyr phosphatase 183 2e-44
gi|7684355|dbj|BAA95199.1| ryPTPN6c [Potamotrygon motoro] 183 2e-44
gi|4249550|dbj|BAA74951.1| phosphotyrosyl protein phosphatase [R... 183 3e-44
gi|9256882|pdb|1GFY|A Chain A, Residue 259 Is A Key Determinant ... 182 5e-44
gi|7435157|pir||JW0049 protein-tyrosine-phosphatase (EC 3.1.3.48... 182 5e-44
gi|22095375|ref|NP_116170.2| hypothetical protein FLJ14427 [Homo... 182 5e-44
gi|40675489|gb|AAH64807.1| PTPN5 protein [Homo sapiens] 182 5e-44
gi|50746555|ref|XP_420550.1| PREDICTED: similar to protein tyros... 182 5e-44
gi|21728414|ref|NP_663716.1| protein-tyrosine phosphatase, non-r... 182 5e-44
gi|27807067|ref|NP_777015.1| protein tyrosine phosphatase, non-r... 182 5e-44
gi|6981442|ref|NP_036769.1| protein tyrosine phosphatase, non-re... 181 8e-44
gi|7766808|pdb|1C86|A Chain A, Crystal Structure Of Protein Tyro... 181 8e-44
gi|50736546|ref|XP_419126.1| PREDICTED: similar to protein tyros... 181 8e-44
gi|13236923|gb|AAB26342.2| tissue-specific protein tyrosine phos... 181 1e-43
gi|24654059|ref|NP_611093.1| CG18243-PA [Drosophila melanogaster... 181 1e-43
gi|6729926|pdb|1BZH|A Chain A, Cyclic Peptide Inhibitor Of Human... 181 1e-43
gi|29726784|pdb|1NWL|A Chain A, Crystal Structure Of The Ptp1b C... 181 1e-43
gi|47219895|emb|CAF97165.1| unnamed protein product [Tetraodon n... 181 1e-43
gi|6729770|pdb|1BZC|A Chain A, Human Ptp1b Catalytic Domain Comp... 181 1e-43
gi|49118658|gb|AAH73687.1| Ptp-2 protein [Xenopus laevis] 181 1e-43
gi|22316173|emb|CAD43435.2| SI:dZ37O5.1 (novel protein tyrosine ... 180 2e-43
gi|22219272|pdb|1LQF|A Chain A, Structure Of Ptp1b In Complex Wi... 180 2e-43
gi|14488467|pdb|1G7F|A Chain A, Human Ptp1b Catalytic Domain Com... 180 2e-43
gi|9588103|emb|CAC00618.1| dJ530I15.1 (protein tyrosine phosphat... 180 2e-43
gi|4506289|ref|NP_002818.1| protein tyrosine phosphatase, non-re... 180 2e-43
gi|37927867|pdb|1Q6J|A Chain A, The Structure Of Phosphotyrosine... 180 2e-43
gi|47124685|gb|AAH70580.1| MGC81077 protein [Xenopus laevis] 180 2e-43
gi|6729771|pdb|1BZJ|A Chain A, Human Ptp1b Complexed With Tpicooh 180 2e-43
gi|809208|pdb|2HNP| Protein-Tyrosine Phosphatase 1b (Human) (E.... 180 2e-43
gi|30584229|gb|AAP36363.1| Homo sapiens protein tyrosine phospha... 180 2e-43
gi|1079313|pir||A55651 protein-tyrosine-phosphatase (EC 3.1.3.48... 180 2e-43
gi|30354339|gb|AAH51975.1| Ptpn5 protein [Mus musculus] 179 3e-43
gi|26332551|dbj|BAC29993.1| unnamed protein product [Mus musculus] 179 3e-43
gi|27735244|sp|P54829|PTN5_HUMAN Protein-tyrosine phosphatase, n... 179 3e-43
gi|957217|gb|AAA87555.1| striatum-enriched phosphatase 179 3e-43
gi|49118310|gb|AAH73317.1| Unknown (protein for MGC:80720) [Xeno... 179 3e-43
gi|7305425|ref|NP_038671.1| protein tyrosine phosphatase, non-re... 179 4e-43
gi|41055194|ref|NP_956748.1| hypothetical protein MGC63553 [Dani... 179 4e-43
gi|6679553|ref|NP_033003.1| protein tyrosine phosphatase, non-re... 179 4e-43
gi|14198420|gb|AAH08269.1| Ptpn2 protein [Mus musculus] >gnl|BL_... 179 4e-43
gi|25058875|gb|AAH39897.1| PTPN5 protein [Homo sapiens] 179 4e-43
gi|9229928|dbj|BAB00633.1| tyrosine phosphatase [Ciona intestina... 179 4e-43
gi|47214683|emb|CAF97207.1| unnamed protein product [Tetraodon n... 179 4e-43
gi|21465993|pdb|1L8G|A Chain A, Crystal Structure Of Ptp1b Compl... 179 4e-43
gi|7546544|pdb|1ECV|A Chain A, Crystal Structure Of Protein Tyro... 179 4e-43
gi|39979291|dbj|BAD05121.1| endostyle specific protein 11 [Ciona... 178 7e-43
gi|29351615|gb|AAH49294.1| Ptp1b protein [Danio rerio] 178 7e-43
gi|39590564|emb|CAE64934.1| Hypothetical protein CBG09764 [Caeno... 178 9e-43
gi|9507009|ref|NP_062126.1| protein tyrosine phosphatase, non-re... 178 9e-43
gi|48096308|ref|XP_392429.1| similar to protein tyrosine phospha... 178 9e-43
gi|2507225|sp|P35821|PTN1_MOUSE Protein-tyrosine phosphatase, no... 177 1e-42
gi|557034|gb|AAA64485.1| PC12-PTP1 177 1e-42
gi|2144714|pir||JC4263 protein-tyrosine-phosphatase (EC 3.1.3.48... 177 2e-42
gi|25091040|sp|O08617|PTPR_RAT Receptor-type protein-tyrosine ph... 177 2e-42
gi|16758376|ref|NP_446046.1| protein tyrosine phosphatase, recep... 177 2e-42
gi|1944500|dbj|BAA19530.1| tyrosine phosphatase CBPTP [Rattus no... 177 2e-42
gi|91245|pir||JN0317 protein-tyrosine-phosphatase (EC 3.1.3.48),... 176 3e-42
gi|13096596|pdb|1G1F|A Chain A, Crystal Structure Of Protein Tyr... 176 3e-42
gi|33096760|emb|CAE11876.1| hypothetical protein [Homo sapiens] 176 3e-42
gi|19743917|ref|NP_570897.1| protein tyrosine phosphatase, recep... 176 3e-42
gi|2078323|gb|AAB54006.1| Ch-1PTPase delta form [Homo sapiens] 176 3e-42
gi|1524069|emb|CAA57957.1| protein-tyrosine-phosphatase [Homo sa... 176 3e-42
>gi|7511581|pir||T19121 probable protein-tyrosine-phosphatase (EC
3.1.3.48), receptor C09D8.1 - Caenorhabditis elegans
Length = 1585
Score = 2266 bits (5872), Expect = 0.0
Identities = 1102/1126 (97%), Positives = 1102/1126 (97%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE
Sbjct: 460 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 519
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS
Sbjct: 520 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 579
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM
Sbjct: 580 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 639
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE
Sbjct: 640 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 699
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV
Sbjct: 700 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 759
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP
Sbjct: 760 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 819
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1262
LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK
Sbjct: 820 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 879
Query: 1263 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXX 1442
SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALT
Sbjct: 880 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTGNIMNGGGGIPG 939
Query: 1443 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 1622
ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN
Sbjct: 940 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 999
Query: 1623 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1802
NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN
Sbjct: 1000 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1059
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW
Sbjct: 1060 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1119
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG
Sbjct: 1120 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 1179
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 2342
EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI
Sbjct: 1180 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 1239
Query: 2343 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 2522
VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR
Sbjct: 1240 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 1299
Query: 2523 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 2702
LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR
Sbjct: 1300 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 1359
Query: 2703 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 2882
VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR
Sbjct: 1360 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 1419
Query: 2883 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 3062
TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF
Sbjct: 1420 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 1479
Query: 3063 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 3242
MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR
Sbjct: 1480 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 1539
Query: 3243 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
AEHVVDVFTTVKLLRTERQNMIQEPEQYHF DNFS
Sbjct: 1540 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNFS 1585
>gi|20871584|emb|CAA86842.3| Hypothetical protein C09D8.1a
[Caenorhabditis elegans]
gi|20871592|emb|CAA90189.3| Hypothetical protein C09D8.1a
[Caenorhabditis elegans]
Length = 2180
Score = 2266 bits (5872), Expect = 0.0
Identities = 1102/1126 (97%), Positives = 1102/1126 (97%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE
Sbjct: 1055 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 1114
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS
Sbjct: 1115 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 1174
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM
Sbjct: 1175 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 1234
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE
Sbjct: 1235 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 1294
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV
Sbjct: 1295 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 1354
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP
Sbjct: 1355 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1414
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1262
LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK
Sbjct: 1415 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1474
Query: 1263 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXX 1442
SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALT
Sbjct: 1475 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTGNIMNGGGGIPG 1534
Query: 1443 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 1622
ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN
Sbjct: 1535 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 1594
Query: 1623 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1802
NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN
Sbjct: 1595 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1654
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW
Sbjct: 1655 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1714
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG
Sbjct: 1715 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 1774
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 2342
EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI
Sbjct: 1775 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 1834
Query: 2343 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 2522
VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR
Sbjct: 1835 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 1894
Query: 2523 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 2702
LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR
Sbjct: 1895 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 1954
Query: 2703 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 2882
VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR
Sbjct: 1955 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 2014
Query: 2883 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 3062
TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF
Sbjct: 2015 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 2074
Query: 3063 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 3242
MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR
Sbjct: 2075 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 2134
Query: 3243 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
AEHVVDVFTTVKLLRTERQNMIQEPEQYHF DNFS
Sbjct: 2135 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNFS 2180
>gi|20871585|emb|CAD31753.1| Hypothetical protein C09D8.1b
[Caenorhabditis elegans]
gi|20871593|emb|CAD31752.1| Hypothetical protein C09D8.1b
[Caenorhabditis elegans]
Length = 1467
Score = 2266 bits (5872), Expect = 0.0
Identities = 1102/1126 (97%), Positives = 1102/1126 (97%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE
Sbjct: 342 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 401
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS
Sbjct: 402 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 461
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM
Sbjct: 462 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 521
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE
Sbjct: 522 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 581
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV
Sbjct: 582 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 641
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP
Sbjct: 642 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 701
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1262
LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK
Sbjct: 702 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 761
Query: 1263 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXX 1442
SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALT
Sbjct: 762 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTGNIMNGGGGIPG 821
Query: 1443 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 1622
ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN
Sbjct: 822 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 881
Query: 1623 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1802
NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN
Sbjct: 882 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 941
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW
Sbjct: 942 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1001
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG
Sbjct: 1002 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 1061
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 2342
EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI
Sbjct: 1062 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 1121
Query: 2343 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 2522
VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR
Sbjct: 1122 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 1181
Query: 2523 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 2702
LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR
Sbjct: 1182 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 1241
Query: 2703 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 2882
VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR
Sbjct: 1242 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 1301
Query: 2883 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 3062
TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF
Sbjct: 1302 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 1361
Query: 3063 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 3242
MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR
Sbjct: 1362 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 1421
Query: 3243 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
AEHVVDVFTTVKLLRTERQNMIQEPEQYHF DNFS
Sbjct: 1422 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNFS 1467
>gi|26985797|emb|CAD59171.1| Hypothetical protein C09D8.1c
[Caenorhabditis elegans]
Length = 1216
Score = 2266 bits (5872), Expect = 0.0
Identities = 1102/1126 (97%), Positives = 1102/1126 (97%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE
Sbjct: 91 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 150
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS
Sbjct: 151 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 210
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM
Sbjct: 211 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 270
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE
Sbjct: 271 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 330
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV
Sbjct: 331 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 390
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP
Sbjct: 391 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 450
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1262
LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK
Sbjct: 451 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 510
Query: 1263 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXX 1442
SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALT
Sbjct: 511 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTGNIMNGGGGIPG 570
Query: 1443 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 1622
ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN
Sbjct: 571 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 630
Query: 1623 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1802
NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN
Sbjct: 631 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 690
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW
Sbjct: 691 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 750
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG
Sbjct: 751 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 810
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 2342
EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI
Sbjct: 811 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 870
Query: 2343 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 2522
VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR
Sbjct: 871 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 930
Query: 2523 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 2702
LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR
Sbjct: 931 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 990
Query: 2703 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 2882
VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR
Sbjct: 991 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 1050
Query: 2883 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 3062
TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF
Sbjct: 1051 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 1110
Query: 3063 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 3242
MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR
Sbjct: 1111 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 1170
Query: 3243 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
AEHVVDVFTTVKLLRTERQNMIQEPEQYHF DNFS
Sbjct: 1171 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLAAYDNFS 1216
>gi|25146572|ref|NP_741043.1| protein tyrosine phosphatase, LAR-like
receptor, affects epidermal cell differentiation,
tyrosine phosphatase (246.6 kD) (ptp-3) [Caenorhabditis
elegans]
gi|29427539|sp|Q9BMN8|LAR_CAEEL Protein-tyrosine phosphatase Lar-like
precursor (Protein-tyrosine-phosphate phosphohydrolase
ptp-3)
gi|12698664|gb|AAK01632.1| PTP-3A [Caenorhabditis elegans]
Length = 2200
Score = 2254 bits (5841), Expect = 0.0
Identities = 1102/1146 (96%), Positives = 1102/1146 (96%), Gaps = 20/1146 (1%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE
Sbjct: 1055 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 1114
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNN--------------------RQGPCSDPPTVLE 302
NPKRFAVVSDLNAHKPYAFCVLAVKNN RQGPCSDPPTVLE
Sbjct: 1115 NPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNEQFNKVRVTNYMTNFQRQGPCSDPPTVLE 1174
Query: 303 SVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGF 482
SVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGF
Sbjct: 1175 SVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGF 1234
Query: 483 GQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKL 662
GQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKL
Sbjct: 1235 GQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKL 1294
Query: 663 VDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQ 842
VDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQ
Sbjct: 1295 VDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQ 1354
Query: 843 LARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYR 1022
LARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYR
Sbjct: 1355 LARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYR 1414
Query: 1023 NNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYS 1202
NNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYS
Sbjct: 1415 NNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYS 1474
Query: 1203 DSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHG 1382
DSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHG
Sbjct: 1475 DSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHG 1534
Query: 1383 SITKVALTXXXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPT 1562
SITKVALT ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPT
Sbjct: 1535 SITKVALTGNIMNGGGGIPGETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPT 1594
Query: 1563 SHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESI 1742
SHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESI
Sbjct: 1595 SHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESI 1654
Query: 1743 ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRS 1922
ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRS
Sbjct: 1655 ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRS 1714
Query: 1923 YIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTL 2102
YIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTL
Sbjct: 1715 YIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTL 1774
Query: 2103 LESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN 2282
LESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN
Sbjct: 1775 LESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN 1834
Query: 2283 DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIF 2462
DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIF
Sbjct: 1835 DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIF 1894
Query: 2463 IHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVAN 2642
IHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVAN
Sbjct: 1895 IHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVAN 1954
Query: 2643 LPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETA 2822
LPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETA
Sbjct: 1955 LPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETA 2014
Query: 2823 ADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLR 3002
ADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLR
Sbjct: 2015 ADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLR 2074
Query: 3003 EFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCC 3182
EFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCC
Sbjct: 2075 EFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCC 2134
Query: 3183 SGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXX 3362
SGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF
Sbjct: 2135 SGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLA 2194
Query: 3363 XXDNFS 3380
DNFS
Sbjct: 2195 AYDNFS 2200
>gi|25146575|ref|NP_741044.1| protein tyrosine phosphatase, LAR-like
receptor, affects epidermal cell differentiation,
tyrosine phosphatase (167.9 kD) (ptp-3) [Caenorhabditis
elegans]
gi|12698666|gb|AAK01633.1| PTP-3B [Caenorhabditis elegans]
Length = 1487
Score = 2254 bits (5841), Expect = 0.0
Identities = 1102/1146 (96%), Positives = 1102/1146 (96%), Gaps = 20/1146 (1%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE
Sbjct: 342 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 401
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNN--------------------RQGPCSDPPTVLE 302
NPKRFAVVSDLNAHKPYAFCVLAVKNN RQGPCSDPPTVLE
Sbjct: 402 NPKRFAVVSDLNAHKPYAFCVLAVKNNLTLNEQFNKVRVTNYMTNFQRQGPCSDPPTVLE 461
Query: 303 SVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGF 482
SVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGF
Sbjct: 462 SVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGF 521
Query: 483 GQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKL 662
GQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKL
Sbjct: 522 GQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKL 581
Query: 663 VDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQ 842
VDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQ
Sbjct: 582 VDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQ 641
Query: 843 LARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYR 1022
LARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYR
Sbjct: 642 LARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYR 701
Query: 1023 NNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYS 1202
NNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYS
Sbjct: 702 NNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYS 761
Query: 1203 DSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHG 1382
DSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHG
Sbjct: 762 DSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHG 821
Query: 1383 SITKVALTXXXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPT 1562
SITKVALT ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPT
Sbjct: 822 SITKVALTGNIMNGGGGIPGETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPT 881
Query: 1563 SHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESI 1742
SHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESI
Sbjct: 882 SHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESI 941
Query: 1743 ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRS 1922
ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRS
Sbjct: 942 ETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRS 1001
Query: 1923 YIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTL 2102
YIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTL
Sbjct: 1002 YIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTL 1061
Query: 2103 LESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN 2282
LESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN
Sbjct: 1062 LESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN 1121
Query: 2283 DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIF 2462
DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIF
Sbjct: 1122 DAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIF 1181
Query: 2463 IHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVAN 2642
IHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVAN
Sbjct: 1182 IHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVAN 1241
Query: 2643 LPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETA 2822
LPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETA
Sbjct: 1242 LPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETA 1301
Query: 2823 ADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLR 3002
ADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLR
Sbjct: 1302 ADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLR 1361
Query: 3003 EFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCC 3182
EFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCC
Sbjct: 1362 EFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCC 1421
Query: 3183 SGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXX 3362
SGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF
Sbjct: 1422 SGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFLYLAAYEYLA 1481
Query: 3363 XXDNFS 3380
DNFS
Sbjct: 1482 AYDNFS 1487
>gi|39597360|emb|CAE59588.1| Hypothetical protein CBG02994
[Caenorhabditis briggsae]
Length = 1462
Score = 2098 bits (5435), Expect = 0.0
Identities = 1010/1126 (89%), Positives = 1056/1126 (93%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPV+SIDKE
Sbjct: 343 LVGPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVLSIDKE 402
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
NPKRFA+VSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV WKTS S
Sbjct: 403 NPKRFAIVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVRWKTSGS 462
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
VQLTW+YNGPRNVGFYVNHTG+KDY+NHEL EKTMSTPGFG D+DEK REYLWTNLRPHM
Sbjct: 463 VQLTWDYNGPRNVGFYVNHTGKKDYMNHELLEKTMSTPGFGHDLDEKTREYLWTNLRPHM 522
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
MYTIHVGVRTLPPGARKYWPQEVVT+TDPTGPPFVDVP+L++SSGTQPGQ MIRLTPATE
Sbjct: 523 MYTIHVGVRTLPPGARKYWPQEVVTVTDPTGPPFVDVPQLIESSGTQPGQHMIRLTPATE 582
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
EYGPISHYWII+VPANYSTEDVVNLD I+LEK+TAEKRAQLARSLSVSPSKKLKR+A
Sbjct: 583 EYGPISHYWIIVVPANYSTEDVVNLDSIDLEKSTAEKRAQLARSLSVSPSKKLKRRAEFS 642
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
D S HPKEKRARRATVPGAYVTARLSADRV+Q YRNNQPF+VGDS+LYDGFTNYP
Sbjct: 643 EDRS-----HPKEKRARRATVPGAYVTARLSADRVRQFYRNNQPFVVGDSKLYDGFTNYP 697
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1262
LEHN HYRLMMRAFAKNDVR KDSFEQRAPMSEKLSRMYSDS+LTEPFTIKSALRGASQK
Sbjct: 698 LEHNSHYRLMMRAFAKNDVRAKDSFEQRAPMSEKLSRMYSDSLLTEPFTIKSALRGASQK 757
Query: 1263 SSPWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXX 1442
SSPWVGACIA +L SIVGML+CWWLRCNKKSAGRHPRHGSITKVALT
Sbjct: 758 SSPWVGACIALFILLSIVGMLVCWWLRCNKKSAGRHPRHGSITKVALTGNIMNGGGMPG- 816
Query: 1443 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPN 1622
ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESS+DLYPLP SHSR+NGYAPVPV +PSLPN
Sbjct: 817 ETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSLDLYPLPRSHSRTNGYAPVPVPLPSLPN 876
Query: 1623 NGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKN 1802
NGNNMTTV+HPAVPIAELANHIERLRMNNN GFQ+EFESIETGQHFTWEHSSA+MNKHKN
Sbjct: 877 NGNNMTTVAHPAVPIAELANHIERLRMNNNIGFQTEFESIETGQHFTWEHSSAEMNKHKN 936
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
RYANVAAYDH+RVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPL ETF+DFWRMVW
Sbjct: 937 RYANVAAYDHTRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLQETFADFWRMVW 996
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
EEQSVTIVMLTNLEERSRVKCDQYWPSRGT++YGDIEVTLLESVHLAHYTMRTMRLKM+G
Sbjct: 997 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTSSYGDIEVTLLESVHLAHYTMRTMRLKMIG 1056
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFI 2342
EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNP+DAGPIISHCSAGIGRTGAFI
Sbjct: 1057 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPHDAGPIISHCSAGIGRTGAFI 1116
Query: 2343 VIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 2522
VIDCMLERLRY+NTVDIYGCVT+LR+QRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR
Sbjct: 1117 VIDCMLERLRYENTVDIYGCVTSLRSQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASR 1176
Query: 2523 LHQHLHILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNR 2702
LHQH+ L QPSADQ+SGIDMEFRHLTTLKWTSNRCTVANLP NR KNRMLSAVPYDSNR
Sbjct: 1177 LHQHVQALMQPSADQMSGIDMEFRHLTTLKWTSNRCTVANLPANRGKNRMLSAVPYDSNR 1236
Query: 2703 VIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVR 2882
VIM ++ G DGSDYINASWIDGYKERGAYIATQAPTNETA DFWR IWEHN PIIAMLV+
Sbjct: 1237 VIMHMISGIDGSDYINASWIDGYKERGAYIATQAPTNETARDFWRLIWEHNCPIIAMLVQ 1296
Query: 2883 TNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHF 3062
T ERGQ+ CSDYWPLETGVQVG LVVEPMAEYDMK+YHLREFR+ DI+T E RTVRQF F
Sbjct: 1297 TRERGQDLCSDYWPLETGVQVGNLVVEPMAEYDMKYYHLREFRLCDIHTNETRTVRQFQF 1356
Query: 3063 MEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 3242
MEWP+VGKPH ADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR
Sbjct: 1357 MEWPEVGKPHKADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMR 1416
Query: 3243 AEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
AEHVVDVFTTVKLLRTERQNMIQEP+QYHF DNFS
Sbjct: 1417 AEHVVDVFTTVKLLRTERQNMIQEPDQYHFLYQAAYEYLAAYDNFS 1462
>gi|31235464|ref|XP_319248.1| ENSANGP00000006103 [Anopheles gambiae]
gi|21302394|gb|EAA14539.1| ENSANGP00000006103 [Anopheles gambiae str.
PEST]
Length = 1889
Score = 736 bits (1900), Expect = 0.0
Identities = 444/1142 (38%), Positives = 617/1142 (53%), Gaps = 18/1142 (1%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGN--RMDTEKWKQLPV-VSIDK 179
GPPT + V + + W+ +++ H G R D + K++ + ++
Sbjct: 878 GPPTGIAVRFQTPDVVCITWEPPTRE---------HRNGQITRYDVQFHKKIDHGLGTER 928
Query: 180 ENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSN 359
R AV ++L+ Y V A GP S+ + +++ + +
Sbjct: 929 NTTVRKAVFTNLDESTEYIVRVRAYTKQGAGPFSEKVVIATERDMGRAPFSVQAVATSEQ 988
Query: 360 SVQLTWEYNGPRN--VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLR 533
+V++ WE R VG+ + +T +L E G + D NL
Sbjct: 989 TVEVWWEPVPSRGKLVGYKIFYTMT---AVEDLDEWQTKVVGVTESAD-------LINLE 1038
Query: 534 PHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTP 713
Y + + G K + V + P P V D G G+++ + P
Sbjct: 1039 KFAQYAVAIAAM-YKTGLGKLSEKATVKMAAPQ--PMVQP----DFYGVVNGEEIQVILP 1091
Query: 714 -ATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRK 890
A+EEYGPISHY++I+VP ED NL I + T E + PS+
Sbjct: 1092 QASEEYGPISHYYLIVVP-----EDKANLHKIPDQFLTEE----------LLPSR----- 1131
Query: 891 ASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGF 1070
PK R + ++ + F +G + F
Sbjct: 1132 --------------PKLDRLNAPYIAAMFLQRNIP-----------YTFHLGSGETNHNF 1166
Query: 1071 TNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEP--------- 1223
TN LE YR+ +RA D K + +P SE L+ ++ EP
Sbjct: 1167 TNKKLERGKRYRIFVRAVV--DTPQKHLYTS-SPFSEFLALDMKEAPTGEPPHRPNPNVP 1223
Query: 1224 FTIKSALRGASQKSSP-WV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKV 1397
+ +RG +++ WV G IA LVL V L+ +++R ++ + P ++T+
Sbjct: 1224 QDTEIIIRGKNEEPGMLWVVGPIIAALVLS--VCFLVVYFVR-RRRQPCKAPDQAAVTRP 1280
Query: 1398 ALTXXXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRS 1577
M + + P PT
Sbjct: 1281 L------------------------------------------MAADLGAGPAPTD---- 1294
Query: 1578 NGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQH 1757
PV + + N +SHP + IAELANH+ERL+ N+N F E+ESIE GQ
Sbjct: 1295 ------PVDMRRI--NFQTPGMISHPPISIAELANHVERLKANDNLKFSQEYESIEPGQQ 1346
Query: 1758 FTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQ 1937
FTW+HS+ ++NK KNRYANV +YDHSRV+L +EG PG DYINANY DGY K +Y+ATQ
Sbjct: 1347 FTWDHSNMEVNKPKNRYANVTSYDHSRVILPPIEGVPGSDYINANYCDGYRKHNAYVATQ 1406
Query: 1938 GPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVH 2117
GPL ETF DFWRM WE +S TIVM+T LEERSR+KCD YWP+RGT YG + VT+ E+
Sbjct: 1407 GPLQETFGDFWRMCWELKSSTIVMMTRLEERSRIKCDMYWPARGTEVYGAMTVTITETQE 1466
Query: 2118 LAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPI 2297
LA Y++RT ++ G E REIK LQ+TAWPDHGVPDHP PFL FL+R K+L P+++GPI
Sbjct: 1467 LATYSIRTFQIYRNGSNERREIKQLQFTAWPDHGVPDHPAPFLQFLRRTKSLTPSESGPI 1526
Query: 2298 ISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAV 2477
I HCSAG+GRTG +IVID MLER++Y+ T+DIYG VT LRAQR+YMVQTE+QYIFIHDA+
Sbjct: 1527 IVHCSAGVGRTGCYIVIDSMLERMKYEKTIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAL 1586
Query: 2478 LDAVNSGSTEVPASRLHQHLHILSQPSA-DQLSGIDMEFRHLTTLKWTSNRCTVANLPVN 2654
L+AV GSTEVPA LH H+ L Q + ++G++MEF+ L+ +K S R ANLP N
Sbjct: 1587 LEAVICGSTEVPARSLHNHIQKLMQTEPHENITGMEMEFKKLSNVKADSTRFVTANLPCN 1646
Query: 2655 RPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFW 2834
+ KNR++ +PY+S+RV + + G +GSDYINAS +DGY+ R AYIA Q P ETA DFW
Sbjct: 1647 KHKNRLVHILPYESSRVCLTPIRGVEGSDYINASLVDGYRYRNAYIAAQGPLQETAEDFW 1706
Query: 2835 RAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRI 3014
R +WEHNS I+ ML + E G+E+C YWP E V+ VV+P+AEY+M Y LREF++
Sbjct: 1707 RMLWEHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQCYVVDPIAEYNMPQYKLREFKV 1766
Query: 3015 SDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAG 3194
+D RTVRQF F++WP+ G P + + F+DF+ QVH T QFG GPITVHC +G G
Sbjct: 1767 TDARDGSSRTVRQFQFIDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVG 1826
Query: 3195 RTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDN 3374
RT VFI LSI+L+RM+ E V+DVF TV++LR++R M+Q +QY F D+
Sbjct: 1827 RTGVFITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYQFCYRAALEYLGSFDH 1886
Query: 3375 FS 3380
++
Sbjct: 1887 YA 1888
Score = 41.2 bits (95), Expect = 0.17
Identities = 45/188 (23%), Positives = 77/188 (40%), Gaps = 2/188 (1%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQWDFES-QKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDK 179
L PT+V + + + ++W ++ + +V++Y + N+ + + +
Sbjct: 288 LPAAPTDVTISEVTATQVRLEWSYKGPEDLQYYVIQYKPKNANQASIVEISGIITM---- 343
Query: 180 ENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMV-QNLRVLWKTS 356
F VV L+ + Y F V+AV N +GP S P T T +N+ V +S
Sbjct: 344 -----FYVVRTLSPYTEYEFYVIAVNNIGRGPPSLPATTTTGETEMESAPRNIEVKPLSS 398
Query: 357 NSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRP 536
+++ +TWE P V TG K Y + S E + + L P
Sbjct: 399 STMLITWE--PPETPNGQV--TGYKVYYTTNPNQPEAS----WDSQMETNDMTTISELTP 450
Query: 537 HMMYTIHV 560
H +YTI V
Sbjct: 451 HAIYTIRV 458
Score = 37.4 bits (85), Expect = 2.5
Identities = 89/423 (21%), Positives = 144/423 (34%), Gaps = 33/423 (7%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWD---FESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE- 182
P N+ V+ S+ST ++ W+ + + + V Y P P S D +
Sbjct: 388 PRNIEVKPLSSSTMLITWEPPETPNGQVTGYKVYYTTNPNQ----------PEASWDSQM 437
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+S+L H Y V A + GP S+P V N R +
Sbjct: 438 ETNDMTTISELTPHAIYTIRVQAFTSMGAGPLSNPVQVKAQQGVPSQPSNFRATDVGETA 497
Query: 363 VQLTWE---YNGPRNVGF--YVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTN 527
V L W ++G V + Y N T Y N + ++ +T Y ++
Sbjct: 498 VTLQWSRPTHSGENIVHYELYWNDT----YANEQHHQRIPNT-----------ETYTLSS 542
Query: 528 LRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRL 707
L P +Y + R+ P V T G P P+ V T P +
Sbjct: 543 LYPDTLYYFWLSARSQRGEGATTPPIPVRTKQYVPGAP----PRNVTVEATSPTTINVSW 598
Query: 708 TPATEE--YGPISHYWIILVPANYS----TEDVVNLDPI---ELEKATAEKRAQLA---- 848
P E G I +Y + V S T +N I EL++ T K LA
Sbjct: 599 LPPPVERSNGAIVYYKVFFVEVGRSDSEATVTTLNSTSIVLDELKRWTEYKIWVLAGTSV 658
Query: 849 -----------RSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLS 995
R+ P KAS V + ++ P +++ R + G ++ +
Sbjct: 659 GDGPRSYPYTVRTHEDVPGDPQDVKASPVNSTTIYVTWKPPKEKNRNGIIRGYHIHVQEM 718
Query: 996 ADRVKQQYRNNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPM 1175
+ K F V D Y+ L+ + Y + + A + K ++ AP+
Sbjct: 719 KEEGKGLLNEPMKFDVVDGLEYN---VTGLQPDTKYSVQVAALTR-----KGDGDRSAPI 770
Query: 1176 SEK 1184
S K
Sbjct: 771 SVK 773
Score = 36.6 bits (83), Expect = 4.2
Identities = 53/214 (24%), Positives = 82/214 (37%), Gaps = 4/214 (1%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQW---DFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
PP NV VEATS +T V W E K R D+E V +++
Sbjct: 580 PPRNVTVEATSPTTINVSWLPPPVERSNGAIVYYKVFFVEVGRSDSE----ATVTTLNST 635
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+ V+ +L Y VLA + GP S P TV Q+++ S +
Sbjct: 636 S----IVLDELKRWTEYKIWVLAGTSVGDGPRSYPYTVRTHEDVPGDPQDVKASPVNSTT 691
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQE-KTMSTPGFGQDVDEKHREYLWTNLRPH 539
+ +TW+ +N + G +V +E K + DV + EY T L+P
Sbjct: 692 IYVTWKPPKEKNRNGIIR--GYHIHVQEMKEEGKGLLNEPMKFDVVD-GLEYNVTGLQPD 748
Query: 540 MMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPP 641
Y++ V T + P +++ P G P
Sbjct: 749 TKYSVQVAALTRKGDGDRSAP---ISVKTPGGVP 779
>gi|20833032|ref|XP_131462.1| protein tyrosine phosphatase, receptor
type, D [Mus musculus]
gi|17225445|gb|AAL37405.1| protein tyrosine phosphatase, receptor
type, delta A [Mus musculus]
gi|17225447|gb|AAL37406.1| protein tyrosine phosphatase, receptor
type, delta A [Mus musculus]
Length = 1254
Score = 726 bits (1875), Expect = 0.0
Identities = 344/618 (55%), Positives = 450/618 (72%), Gaps = 1/618 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + + PV + L N SHP +PI ELA+HIERL+ N+
Sbjct: 638 ESESRKSSLPNSKEVPSHHPTDPVELRRL--NFQTPGMASHPPIPILELADHIERLKAND 695
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DY+NA
Sbjct: 696 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNA 755
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQG LPETF DFWRM+WE++S T+VM+T LEERSRVKCDQYWPSRG
Sbjct: 756 NYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRG 815
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T T+G ++VTLL++V LA Y +RT L G E RE++ Q+TAWPDHGVP+HPTPFL
Sbjct: 816 TETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLA 875
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+
Sbjct: 876 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 935
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L +
Sbjct: 936 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 995
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS++DGY+++ A
Sbjct: 996 SKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKA 1055
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 1056 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1115
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 1116 MAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1175
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY
Sbjct: 1176 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 1235
Query: 3327 HFXXXXXXXXXXXXDNFS 3380
F D+++
Sbjct: 1236 QFCYRAALEYLGSFDHYA 1253
Score = 39.3 bits (90), Expect = 0.65
Identities = 63/256 (24%), Positives = 111/256 (42%), Gaps = 20/256 (7%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ + H+P N + P ID
Sbjct: 79 PGTPVVTESTATSITLT-WDSGNPEPVSYYI-IQHKPKNSEE-------PYKEIDGIATT 129
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
R++V L+ + Y F V+AV N +GP S+P T P+ ++++ +S ++
Sbjct: 130 RYSVAG-LSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 188
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKH---RE 512
+ W E NG + G+ V +T +++ H + + ++T G V +K +
Sbjct: 189 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITT--IGNLVPQKTYSVKV 245
Query: 513 YLWTNLRPHMMYT-IHVGVRTLPPGAR---KYWPQEVVTITDPTGPPFVDV---PKLVDS 671
+T++ + + I V +T PG K P+ +I PP D +LV
Sbjct: 246 LAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVYR 305
Query: 672 SGTQPGQQMIRLTPAT 719
G Q +Q I + P T
Sbjct: 306 DGDQGEEQRITIEPGT 321
>gi|19263606|gb|AAH25145.1| Ptprd protein [Mus musculus]
Length = 749
Score = 726 bits (1875), Expect = 0.0
Identities = 344/618 (55%), Positives = 450/618 (72%), Gaps = 1/618 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + + PV + L N SHP +PI ELA+HIERL+ N+
Sbjct: 133 ESESRKSSLPNSKEVPSHHPTDPVELRRL--NFQTPGMASHPPIPILELADHIERLKAND 190
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DY+NA
Sbjct: 191 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNA 250
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQG LPETF DFWRM+WE++S T+VM+T LEERSRVKCDQYWPSRG
Sbjct: 251 NYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRG 310
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T T+G ++VTLL++V LA Y +RT L G E RE++ Q+TAWPDHGVP+HPTPFL
Sbjct: 311 TETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLA 370
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+
Sbjct: 371 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 430
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L +
Sbjct: 431 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 490
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS++DGY+++ A
Sbjct: 491 SKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKA 550
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 551 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 610
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 611 MAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 670
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY
Sbjct: 671 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 730
Query: 3327 HFXXXXXXXXXXXXDNFS 3380
F D+++
Sbjct: 731 QFCYRAALEYLGSFDHYA 748
>gi|34869007|ref|XP_233065.2| similar to protein tyrosine phosphatase,
receptor type, D isoform 3 precursor; protein tyrosine
phosphatase, receptor type, delta polypeptide; protein
tyrosine phosphatase delta [Rattus norvegicus]
Length = 1811
Score = 726 bits (1875), Expect = 0.0
Identities = 344/618 (55%), Positives = 450/618 (72%), Gaps = 1/618 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + + PV + L N SHP +PI ELA+HIERL+ N+
Sbjct: 1195 ESESRKSSLPNSKEVPSHHPTDPVELRRL--NFQTPGMASHPPIPILELADHIERLKAND 1252
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DY+NA
Sbjct: 1253 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNA 1312
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQG LPETF DFWRM+WE++S T+VM+T LEERSRVKCDQYWPSRG
Sbjct: 1313 NYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVVMMTKLEERSRVKCDQYWPSRG 1372
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T T+G ++VTLL++V LA Y +RT L G E RE++ Q+TAWPDHGVP+HPTPFL
Sbjct: 1373 TETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLA 1432
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+
Sbjct: 1433 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 1492
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L +
Sbjct: 1493 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 1552
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS++DGY+++ A
Sbjct: 1553 SKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFLDGYRQQKA 1612
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 1613 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1672
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 1673 MAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1732
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY
Sbjct: 1733 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 1792
Query: 3327 HFXXXXXXXXXXXXDNFS 3380
F D+++
Sbjct: 1793 QFCYRAALEYLGSFDHYA 1810
Score = 38.9 bits (89), Expect = 0.85
Identities = 52/220 (23%), Positives = 91/220 (40%), Gaps = 10/220 (4%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ + H+P N + P ID
Sbjct: 228 PGTPVVTESTATSITLT-WDSGNPEPVSYYI-IQHKPKNSEE-------PYKEIDGIATT 278
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
R++V L+ + Y F V+AV N +GP S+P T P+ ++++ +S ++
Sbjct: 279 RYSVAG-LSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 337
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
+ W E NG + G+ V +T +++ H + + ++T G
Sbjct: 338 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG-------------- 382
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPP 641
NL P Y++ V T +V+T T G P
Sbjct: 383 -NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP 421
>gi|4506309|ref|NP_002830.1| protein tyrosine phosphatase, receptor
type, D isoform 1 precursor; protein tyrosine
phosphatase, receptor type, delta polypeptide; protein
tyrosine phosphatase delta [Homo sapiens]
gi|1709906|sp|P23468|PTPD_HUMAN Protein-tyrosine phosphatase delta
precursor (R-PTP-delta)
gi|1362917|pir||A56178 protein-tyrosine-phosphatase (EC 3.1.3.48),
receptor type delta precursor - human
gi|755653|gb|AAC41749.1| protein tyrosine phosphatase delta
Length = 1912
Score = 726 bits (1874), Expect = 0.0
Identities = 336/579 (58%), Positives = 438/579 (75%), Gaps = 1/579 (0%)
Frame = +3
Query: 1647 SHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAY 1826
SHP +PI ELA+HIERL+ N+N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AY
Sbjct: 1333 SHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAY 1392
Query: 1827 DHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIV 2006
DHSRV+LS +EG PG DY+NANY+DGY K +YIATQG LPETF DFWRM+WE++S T+V
Sbjct: 1393 DHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVV 1452
Query: 2007 MLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIK 2186
M+T LEERSRVKCDQYWPSRGT T+G ++VTLL++V LA Y +RT L G E RE++
Sbjct: 1453 MMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVR 1512
Query: 2187 HLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLER 2366
Q+TAWPDHGVP+HPTPFL FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER
Sbjct: 1513 QFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLER 1572
Query: 2367 LRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHIL 2546
++++ TVDIYG VT +RAQR+YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L
Sbjct: 1573 IKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKL 1632
Query: 2547 SQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLP 2723
+Q + + ++G+++EF+ L + K ++R ANLP N+ KNR+++ +PY+S RV ++ +
Sbjct: 1633 TQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIR 1692
Query: 2724 GADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQE 2903
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E
Sbjct: 1693 GVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE 1752
Query: 2904 QCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVG 3083
+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G
Sbjct: 1753 KCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQG 1812
Query: 3084 KPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDV 3263
P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+
Sbjct: 1813 VPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDI 1872
Query: 3264 FTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
F TVK+LRT+R M+Q +QY F D+++
Sbjct: 1873 FQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYA 1911
Score = 39.3 bits (90), Expect = 0.65
Identities = 57/274 (20%), Positives = 112/274 (40%), Gaps = 10/274 (3%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ + H+P N E +K++ V+ + +
Sbjct: 326 PGTPVVTESTATSITLT-WDSGNPEPVSYYI-IQHKPKN--SEELYKEIDGVATTRYS-- 379
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
V+ L+ + Y F V+AV N +GP S+P T P+ ++++ +S ++
Sbjct: 380 ----VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
+ W E NG + G+ V +T +++ H + + ++T G
Sbjct: 436 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG-------------- 480
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
NL P Y++ V T +V+T T G P ++ + I
Sbjct: 481 -NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP-------LNFKAEPESETSI 532
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDP 803
L+ I++Y ++ + E + ++P
Sbjct: 533 LLSWTPPRSDTIANYELVYKDGEHGEEQRITIEP 566
>gi|18860892|ref|NP_569076.1| protein tyrosine phosphatase, receptor
type, D isoform 3 precursor; protein tyrosine
phosphatase, receptor type, delta polypeptide; protein
tyrosine phosphatase delta [Homo sapiens]
Length = 1903
Score = 726 bits (1874), Expect = 0.0
Identities = 336/579 (58%), Positives = 438/579 (75%), Gaps = 1/579 (0%)
Frame = +3
Query: 1647 SHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAY 1826
SHP +PI ELA+HIERL+ N+N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AY
Sbjct: 1324 SHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAY 1383
Query: 1827 DHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIV 2006
DHSRV+LS +EG PG DY+NANY+DGY K +YIATQG LPETF DFWRM+WE++S T+V
Sbjct: 1384 DHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVV 1443
Query: 2007 MLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIK 2186
M+T LEERSRVKCDQYWPSRGT T+G ++VTLL++V LA Y +RT L G E RE++
Sbjct: 1444 MMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVR 1503
Query: 2187 HLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLER 2366
Q+TAWPDHGVP+HPTPFL FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER
Sbjct: 1504 QFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLER 1563
Query: 2367 LRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHIL 2546
++++ TVDIYG VT +RAQR+YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L
Sbjct: 1564 IKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKL 1623
Query: 2547 SQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLP 2723
+Q + + ++G+++EF+ L + K ++R ANLP N+ KNR+++ +PY+S RV ++ +
Sbjct: 1624 TQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIR 1683
Query: 2724 GADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQE 2903
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E
Sbjct: 1684 GVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE 1743
Query: 2904 QCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVG 3083
+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G
Sbjct: 1744 KCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQG 1803
Query: 3084 KPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDV 3263
P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+
Sbjct: 1804 VPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDI 1863
Query: 3264 FTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
F TVK+LRT+R M+Q +QY F D+++
Sbjct: 1864 FQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYA 1902
Score = 39.3 bits (90), Expect = 0.65
Identities = 57/274 (20%), Positives = 112/274 (40%), Gaps = 10/274 (3%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ + H+P N E +K++ V+ + +
Sbjct: 326 PGTPVVTESTATSITLT-WDSGNPEPVSYYI-IQHKPKN--SEELYKEIDGVATTRYS-- 379
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
V+ L+ + Y F V+AV N +GP S+P T P+ ++++ +S ++
Sbjct: 380 ----VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
+ W E NG + G+ V +T +++ H + + ++T G
Sbjct: 436 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG-------------- 480
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
NL P Y++ V T +V+T T G P ++ + I
Sbjct: 481 -NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP-------LNFKAEPESETSI 532
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDP 803
L+ I++Y ++ + E + ++P
Sbjct: 533 LLSWTPPRSDTIANYELVYKDGEHGEEQRITIEP 566
>gi|18860894|ref|NP_569077.1| protein tyrosine phosphatase, receptor
type, D isoform 4 precursor; protein tyrosine
phosphatase, receptor type, delta polypeptide; protein
tyrosine phosphatase delta [Homo sapiens]
Length = 1501
Score = 726 bits (1874), Expect = 0.0
Identities = 336/579 (58%), Positives = 438/579 (75%), Gaps = 1/579 (0%)
Frame = +3
Query: 1647 SHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAY 1826
SHP +PI ELA+HIERL+ N+N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AY
Sbjct: 922 SHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAY 981
Query: 1827 DHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIV 2006
DHSRV+LS +EG PG DY+NANY+DGY K +YIATQG LPETF DFWRM+WE++S T+V
Sbjct: 982 DHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVV 1041
Query: 2007 MLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIK 2186
M+T LEERSRVKCDQYWPSRGT T+G ++VTLL++V LA Y +RT L G E RE++
Sbjct: 1042 MMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVR 1101
Query: 2187 HLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLER 2366
Q+TAWPDHGVP+HPTPFL FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER
Sbjct: 1102 QFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLER 1161
Query: 2367 LRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHIL 2546
++++ TVDIYG VT +RAQR+YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L
Sbjct: 1162 IKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKL 1221
Query: 2547 SQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLP 2723
+Q + + ++G+++EF+ L + K ++R ANLP N+ KNR+++ +PY+S RV ++ +
Sbjct: 1222 TQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIR 1281
Query: 2724 GADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQE 2903
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E
Sbjct: 1282 GVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE 1341
Query: 2904 QCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVG 3083
+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G
Sbjct: 1342 KCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQG 1401
Query: 3084 KPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDV 3263
P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+
Sbjct: 1402 VPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDI 1461
Query: 3264 FTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
F TVK+LRT+R M+Q +QY F D+++
Sbjct: 1462 FQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYA 1500
Score = 39.7 bits (91), Expect = 0.50
Identities = 73/362 (20%), Positives = 141/362 (38%), Gaps = 11/362 (3%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ + H+P N E +K++ V+ + +
Sbjct: 326 PGTPVVTESTATSITLT-WDSGNPEPVSYYI-IQHKPKN--SEELYKEIDGVATTRYS-- 379
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
V+ L+ + Y F V+AV N +GP S+P T P+ ++++ +S ++
Sbjct: 380 ----VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 435
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
+ W E NG + G+ V +T +++ H + + ++T G
Sbjct: 436 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG-------------- 480
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
NL P Y++ V T +V+T T G P ++ + I
Sbjct: 481 -NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP-------LNFKAEPESETSI 532
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKL 881
L+ I++Y ++ + E + ++P R Q + S+ +
Sbjct: 533 LLSWTPPRSDTIANYELVYKDGEHGEEQRITIEP------GTSYRLQGLKPNSLYYFRLA 586
Query: 882 KRKASEVGDDSQSASYHPKEKR-ARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQL 1058
R +G + S + A+ V T+ L + + + Y + PF + L
Sbjct: 587 ARSPQGLGASTAEISARTMQSMFAKNFHVKAVMKTSVLLSWEIPENYNSAMPFKI----L 642
Query: 1059 YD 1064
YD
Sbjct: 643 YD 644
>gi|18860890|ref|NP_569075.1| protein tyrosine phosphatase, receptor
type, D isoform 2 precursor; protein tyrosine
phosphatase, receptor type, delta polypeptide; protein
tyrosine phosphatase delta [Homo sapiens]
Length = 1899
Score = 726 bits (1874), Expect = 0.0
Identities = 336/579 (58%), Positives = 438/579 (75%), Gaps = 1/579 (0%)
Frame = +3
Query: 1647 SHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAY 1826
SHP +PI ELA+HIERL+ N+N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AY
Sbjct: 1320 SHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAY 1379
Query: 1827 DHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIV 2006
DHSRV+LS +EG PG DY+NANY+DGY K +YIATQG LPETF DFWRM+WE++S T+V
Sbjct: 1380 DHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVV 1439
Query: 2007 MLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIK 2186
M+T LEERSRVKCDQYWPSRGT T+G ++VTLL++V LA Y +RT L G E RE++
Sbjct: 1440 MMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVR 1499
Query: 2187 HLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLER 2366
Q+TAWPDHGVP+HPTPFL FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER
Sbjct: 1500 QFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLER 1559
Query: 2367 LRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHIL 2546
++++ TVDIYG VT +RAQR+YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L
Sbjct: 1560 IKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKL 1619
Query: 2547 SQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLP 2723
+Q + + ++G+++EF+ L + K ++R ANLP N+ KNR+++ +PY+S RV ++ +
Sbjct: 1620 TQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIR 1679
Query: 2724 GADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQE 2903
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E
Sbjct: 1680 GVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE 1739
Query: 2904 QCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVG 3083
+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G
Sbjct: 1740 KCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQG 1799
Query: 3084 KPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDV 3263
P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+
Sbjct: 1800 VPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDI 1859
Query: 3264 FTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
F TVK+LRT+R M+Q +QY F D+++
Sbjct: 1860 FQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYA 1898
Score = 39.3 bits (90), Expect = 0.65
Identities = 57/274 (20%), Positives = 112/274 (40%), Gaps = 10/274 (3%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ + H+P N E +K++ V+ + +
Sbjct: 313 PGTPVVTESTATSITLT-WDSGNPEPVSYYI-IQHKPKN--SEELYKEIDGVATTRYS-- 366
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
V+ L+ + Y F V+AV N +GP S+P T P+ ++++ +S ++
Sbjct: 367 ----VAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTIL 422
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
+ W E NG + G+ V +T +++ H + + ++T G
Sbjct: 423 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIG-------------- 467
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
NL P Y++ V T +V+T T G P ++ + I
Sbjct: 468 -NLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQP-------LNFKAEPESETSI 519
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDP 803
L+ I++Y ++ + E + ++P
Sbjct: 520 LLSWTPPRSDTIANYELVYKDGEHGEEQRITIEP 553
>gi|35790|emb|CAA38068.1| protein-tyrosine phosphatase [Homo sapiens]
Length = 1523
Score = 726 bits (1874), Expect = 0.0
Identities = 336/579 (58%), Positives = 438/579 (75%), Gaps = 1/579 (0%)
Frame = +3
Query: 1647 SHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAY 1826
SHP +PI ELA+HIERL+ N+N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AY
Sbjct: 944 SHPPIPILELADHIERLKANDNLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAY 1003
Query: 1827 DHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIV 2006
DHSRV+LS +EG PG DY+NANY+DGY K +YIATQG LPETF DFWRM+WE++S T+V
Sbjct: 1004 DHSRVLLSAIEGIPGSDYVNANYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQRSATVV 1063
Query: 2007 MLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIK 2186
M+T LEERSRVKCDQYWPSRGT T+G ++VTLL++V LA Y +RT L G E RE++
Sbjct: 1064 MMTKLEERSRVKCDQYWPSRGTETHGLVQVTLLDTVELATYCVRTFALYKNGSSEKREVR 1123
Query: 2187 HLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLER 2366
Q+TAWPDHGVP+HPTPFL FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER
Sbjct: 1124 QFQFTAWPDHGVPEHPTPFLAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLER 1183
Query: 2367 LRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHIL 2546
++++ TVDIYG VT +RAQR+YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L
Sbjct: 1184 IKHEKTVDIYGHVTLMRAQRNYMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKL 1243
Query: 2547 SQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLP 2723
+Q + + ++G+++EF+ L + K ++R ANLP N+ KNR+++ +PY+S RV ++ +
Sbjct: 1244 TQIETGENVTGMELEFKRLASSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIR 1303
Query: 2724 GADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQE 2903
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E
Sbjct: 1304 GVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGRE 1363
Query: 2904 QCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVG 3083
+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G
Sbjct: 1364 KCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQG 1423
Query: 3084 KPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDV 3263
P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+
Sbjct: 1424 VPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDI 1483
Query: 3264 FTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
F TVK+LRT+R M+Q +QY F D+++
Sbjct: 1484 FQTVKMLRTQRPAMVQTEDQYQFSYRAALEYLGSFDHYA 1522
>gi|1079024|pir||S53089 protein-tyrosine-phosphatase (EC 3.1.3.48)
AnLAR - African malaria mosquito (fragment)
gi|732550|emb|CAA59483.1| Anlar [Anopheles gambiae]
Length = 1231
Score = 724 bits (1870), Expect = 0.0
Identities = 440/1138 (38%), Positives = 606/1138 (52%), Gaps = 16/1138 (1%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPKR 194
P +V+ ATS T V W+ + K + D ++W Q VV + +
Sbjct: 212 PFSVQAVATSEQTVEVWWEPVPSRGKLVGYKIFYTMTAVEDLDEW-QTKVVGVTES---- 266
Query: 195 FAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLT 374
A + +L YA + A+ G S+ TV V P + NLR +++S+ L+
Sbjct: 267 -ADLINLEKFAQYAVAIAAMYKTGLGKLSEKATV--KVKPEDVPLNLRAHDVSTHSMTLS 323
Query: 375 WEYNGPRN-VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYT 551
W N + + ++ K++V+ + + P + + + + L P Y
Sbjct: 324 WAPPIRLNPINYKISFDAVKEFVDSQGISQKQILPRKEIILKSHVKSHTISELSPFTTYF 383
Query: 552 IHVGVRTLPPGARKYWPQEVVTITDPTGP--PFVDVPKLVDSSGTQPGQQMIRLTP-ATE 722
++V P Y P +T+T P V D G G+++ + P A+E
Sbjct: 384 VNVSA---VPTDYSYKPPAKITVTTQMAARSPMVQP----DFYGVVNGEEIQVILPQASE 436
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
YGPISHY++I+VP ED NL I + T E + PS+
Sbjct: 437 GYGPISHYYLIVVP-----EDKANLYKIPDQGLTEE----------LLPSR--------- 472
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
PK R + ++ + F +G + FTN
Sbjct: 473 ----------PKLDRLNAPYMAAMFLQRNIP-----------YTFHLGSGETNHNFTNKK 511
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQK 1262
LE YR+ +RA D K + +P SE L+ ++ T P + +K
Sbjct: 512 LERGKRYRIFVRAVV--DTPQKHLYTS-SPFSEFLALDMKEAPTTNPRIVPIPTFPQIRK 568
Query: 1263 SS-----------PWVGACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTX 1409
S +VG IA LVLF ++ + R ++ + P ++T+
Sbjct: 569 LSFVPKMKSRACFGYVGPIIAALVLFRPASCVVYFVRR--RRQPCKAPDQAAVTRPL--- 623
Query: 1410 XXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYA 1589
M + + P PT
Sbjct: 624 ---------------------------------------MAADLGAGPAPTD-------- 636
Query: 1590 PVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWE 1769
PV + + N +SHP + IAEL NH+E L+ N+N F E+ESIE GQ FTW+
Sbjct: 637 --PVDMRRI--NFQTPGMISHPPISIAELPNHVEPLKANDNLKFSQEYESIEPGQQFTWD 692
Query: 1770 HSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLP 1949
HS+ ++NK KNRYANV +YDHSRV+L +E PG DYINANY DGY K +Y+ATQGPL
Sbjct: 693 HSNMEVNKPKNRYANVTSYDHSRVILPPIERVPGSDYINANYCDGYRKHNAYVATQGPLQ 752
Query: 1950 ETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHY 2129
ETF DFWRM WE +S TIVM+T LEERSR+KC YWPSRGT YG + VT+ E+ LA Y
Sbjct: 753 ETFGDFWRMCWELKSSTIVMMTRLEERSRIKCTMYWPSRGTEVYGAMTVTITETQELATY 812
Query: 2130 TMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHC 2309
++RT +L G E REIK LQ+TAWPDHGVPDHP PFL FL+R K + P+++GPII HC
Sbjct: 813 SIRTFQLYRNGSNERREIKQLQFTAWPDHGVPDHPAPFLQFLRRTKVVTPSESGPIIVHC 872
Query: 2310 SAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAV 2489
SAG+G TG FIVID MLER++Y+ T+DIYG VT LRA R+YMVQTE+QYIFIHDA+L+AV
Sbjct: 873 SAGVGVTGCFIVIDSMLERMKYEKTIDIYGHVTCLRAHRNYMVQTEDQYIFIHDALLEAV 932
Query: 2490 NSGSTEVPASRLHQHLHILSQPSA-DQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
GSTEVPA LH H+ L Q + ++G++MEF+ L+ +K S R ANLP N+ K
Sbjct: 933 ICGSTEVPARSLHNHIQKLMQTEPHENITGMEMEFKKLSNVKADSTRFVTANLPCNKHKT 992
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+ +PY+S+RV + + G +GSDYINAS +DGY+ R YIA Q P ETA DFWR +W
Sbjct: 993 RVPHILPYESSRVCLTPIRGVEGSDYINASLVDGYRYRKRYIAAQGPLQETAEDFWRMLW 1052
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
EHNS I+ ML + E G+E+C YWP E V+ VV+P+AEY+M Y LREF+++D
Sbjct: 1053 EHNSTIVVMLTKLKEMGREKCFQYWPHERSVRYQCYVVDPIAEYNMPQYKLREFKVTDAR 1112
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
RTVRQF F+ WP+ G P + F+DF+ QVH T QFG GPITVHC +G GRT V
Sbjct: 1113 DGSSRTVRQFQFITWPEQGVPKSGQGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGV 1172
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RM+ E V+DVF TV++LR++R M+Q +QY F D+++
Sbjct: 1173 FITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYQFCYRAALEYLGSLDHYA 1230
>gi|7248657|gb|AAF43605.1| receptor protein tyrosine phosphatase delta
[Xenopus laevis]
Length = 1896
Score = 723 bits (1866), Expect = 0.0
Identities = 342/602 (56%), Positives = 444/602 (72%), Gaps = 1/602 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + PV + L N +HP +PI EL +HIERL+ N+
Sbjct: 1280 ESDSRKSSLPNSKEIPSHNPTDPVELRRL--NFQTPGMANHPPIPILELEDHIERLKAND 1337
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS ++G PG DYIN+
Sbjct: 1338 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIDGIPGSDYINS 1397
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQGPLPETF DFWRM+WE++S T+VM+T +EERSR+KCDQYWPSRG
Sbjct: 1398 NYIDGYRKQNAYIATQGPLPETFGDFWRMMWEQRSATVVMMTKMEERSRIKCDQYWPSRG 1457
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T TYG I+VTLL++V LA YT+RT L G E RE++ Q+TAWPDHGVP+HPTPFL
Sbjct: 1458 TETYGLIQVTLLDTVELATYTVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLA 1517
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL+RVKT NP DAGP++ HCSAG+GRTG F VID MLER+R++ TVDIYG VT +RAQR+
Sbjct: 1518 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFNVIDAMLERIRHEKTVDIYGHVTLMRAQRN 1577
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + ++G+++EF+ L +
Sbjct: 1578 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIEPGENVTGMELEFKRLAS 1637
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS+IDGY+++ A
Sbjct: 1638 FKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKA 1697
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 1698 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1757
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 1758 MAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1817
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R ++Q +QY
Sbjct: 1818 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQY 1877
Query: 3327 HF 3332
F
Sbjct: 1878 QF 1879
Score = 223 bits (568), Expect = 2e-56
Identities = 117/293 (39%), Positives = 168/293 (56%), Gaps = 8/293 (2%)
Frame = +3
Query: 1641 TVSHPAVPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKN 1802
T + VP L +I++L N G + EF+ + + + T SA++ NK KN
Sbjct: 1598 TCGNTEVPARNLYAYIQKLTQIEPGENVTGMELEFKRLASFKAHTSRFISANLPCNKFKN 1657
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
R N+ Y+ +RV L + G G DYINA+++DGY + ++YIATQGPL ET DFWRM+W
Sbjct: 1658 RLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLW 1717
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
E S +VMLT L E R KC QYWP+ +A Y V + ++ Y +R ++
Sbjct: 1718 EHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1777
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGA 2336
+ + R ++ Q+T WP+ GVP F+ F+ +V GPI HCSAG+GRTG
Sbjct: 1778 DGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGV 1837
Query: 2337 FIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNS 2495
FI + +LER+RY+ VDI+ V LR QR +VQTE+QY F + A L+ + S
Sbjct: 1838 FITLSIVLERMRYEGVVDIFQTVKMLRTQRPAVVQTEDQYQFCYRAGLEYLGS 1890
Score = 39.7 bits (91), Expect = 0.50
Identities = 29/124 (23%), Positives = 61/124 (48%), Gaps = 1/124 (0%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
PP V ++ ++ + WD + + S+ + H+P + E++K++ V+ + +
Sbjct: 319 PPGTPMVTESTATSITLTWDSGNPEPVSYYI-IQHKP--KSSEEQYKEIDGVATTRYS-- 373
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDP-PTVLESVTPTYMVQNLRVLWKTSNSVQ 368
V+ L+ + Y F V+AV N +GP S+P T P+ +N++ +S ++
Sbjct: 374 ----VAGLSPYSEYEFRVVAVNNIGRGPPSEPVMTRTSEQAPSSPPRNVQARMLSSTTIL 429
Query: 369 LTWE 380
+ WE
Sbjct: 430 VQWE 433
Score = 38.1 bits (87), Expect = 1.4
Identities = 28/125 (22%), Positives = 53/125 (42%), Gaps = 3/125 (2%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
PP NV+ S++T +VQW+ + + + V Y +P +++ W + V
Sbjct: 414 PPRNVQARMLSSTTILVQWEEPEEPNGQIQGYRVYYTMDPTQHINS--WTKHNVAD---- 467
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+ + +L K Y+ VLA + GP S+ V+ N + ++ S
Sbjct: 468 --SQITTIGNLEPQKTYSVKVLAFTSVGDGPLSNDIQVITQTGVPSQPLNFKAEPESETS 525
Query: 363 VQLTW 377
+ L+W
Sbjct: 526 ILLSW 530
>gi|19743925|ref|NP_570925.1| protein tyrosine phosphatase, receptor
type, sigma isoform 4 precursor; protein tyrosine
phosphatase PTPsigma [Homo sapiens]
Length = 1505
Score = 719 bits (1856), Expect = 0.0
Identities = 435/1138 (38%), Positives = 611/1138 (53%), Gaps = 14/1138 (1%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYM---------HEPGNRMDTEKWKQLP 161
G P N+R EA S ++ + W Q++ ++KY E G D
Sbjct: 517 GQPMNLRAEARSETSITLSWSPPRQES---IIKYELLFREGDHGREVGRTFD-------- 565
Query: 162 VVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV 341
P VV DL + YAF + A + QG + P V + + +N +V
Sbjct: 566 --------PTTSYVVEDLKPNTEYAFRLAA--RSPQGLGAFTPVVRQRTLQSISPKNFKV 615
Query: 342 LWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
SV L+WE+ P N Y + T K N G DVD + + L
Sbjct: 616 KMIMKTSVLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLI 659
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
T+L+PH Y + R G + T+T T ++ V G M+
Sbjct: 660 THLKPHTFYNFVLTNRGSSLGGLQQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMV 713
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKL 881
L P + P+ Y+I++VP S + Q L L
Sbjct: 714 YL-PDGQSPVPVQSYFIVMVPLRKS------------------RGGQFLTPLGSPEDMDL 754
Query: 882 KRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLY 1061
+ ++ + + H +R+ VP Y+ AR S F GD + Y
Sbjct: 755 EELIQDISRLQRRSLRH-----SRQLEVPRPYIAARFSV--------LPPTFHPGDQKQY 801
Query: 1062 DGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSA 1241
GF N LE Y L + A + +K ++ S ++PF + +
Sbjct: 802 GGFDNRGLEPGHRYVLFVLA-----------------VLQKSEPTFAASPFSDPFQLDNP 844
Query: 1242 LRGA---SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTX 1409
++ WV G +A + + IV ++ + + + K PR
Sbjct: 845 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR----------- 893
Query: 1410 XXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYA 1589
T LL+ ++ + P HH + P R N
Sbjct: 894 ------------TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQT 921
Query: 1590 PVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWE 1769
P ++ P + PIA++A H ERL+ N++ E+ESI+ GQ FTWE
Sbjct: 922 PGMLSHPPI---------------PIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWE 966
Query: 1770 HSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLP 1949
HS+ ++NK KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLP
Sbjct: 967 HSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLP 1026
Query: 1950 ETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHY 2129
ETF DFWRMVWE++S TIVM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA +
Sbjct: 1027 ETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATF 1086
Query: 2130 TMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHC 2309
+RT L G E RE++ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HC
Sbjct: 1087 CVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHC 1146
Query: 2310 SAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAV 2489
SAG+GRTG FIVID MLER++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV
Sbjct: 1147 SAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAV 1206
Query: 2490 NSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
G+TEVPA L+ ++ L+Q + ++G+++EF+ L K ++R ANLP N+ KN
Sbjct: 1207 GCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKN 1266
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+++ +PY+S RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +W
Sbjct: 1267 RLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLW 1326
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
E+NS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D
Sbjct: 1327 ENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1386
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
+ RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT V
Sbjct: 1387 DGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGV 1446
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1447 FITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1504
Score = 37.0 bits (84), Expect = 3.2
Identities = 49/205 (23%), Positives = 79/205 (37%), Gaps = 9/205 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 421 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 469
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 470 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSE 529
Query: 357 NSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWTN 527
S+ L+W + PR ++ + +EL G++V + Y+ +
Sbjct: 530 TSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVED 574
Query: 528 LRPHMMYTIHVGVRTLPPGARKYWP 602
L+P+ Y + R+ P G + P
Sbjct: 575 LKPNTEYAFRLAARS-PQGLGAFTP 598
>gi|2118906|pir||I58148 protein-tyrosine-phosphatase (EC 3.1.3.48) 2B,
splice form LAR - rat
gi|294574|gb|AAC37657.1| leukocyte common antigen-related phosphatase
gi|310243|gb|AAA42309.1| protein tyrosine phosphatase [Rattus
norvegicus]
gi|738734|prf||2001393A protein Tyr phosphatase 2
Length = 1501
Score = 719 bits (1856), Expect = 0.0
Identities = 437/1131 (38%), Positives = 622/1131 (54%), Gaps = 7/1131 (0%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKY--MHEPGNRMDTEKWKQLPVVSIDKE 182
G P N+R EA S ++ + W Q++ V+KY + G+R E +
Sbjct: 513 GQPMNLRAEAKSETSIGLSWSAPRQES---VIKYELLFREGDR-GREVGRTF-------- 560
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+P VV DL + YAF + A + QG + V + +N +V S
Sbjct: 561 DPTTAFVVEDLKPNTEYAFRLAA--RSPQGLGAFTAVVCQRTLQAISPKNFKVKMIMKTS 618
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
V L+WE+ P N Y + T K N G DVD + + L T+L+PH
Sbjct: 619 VLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHT 662
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
Y + R G + +G P V PK D+ G+ ++ P +
Sbjct: 663 FYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGS-----IVVYLPDGQ 715
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
+ +Y+I++VP S PI L +L + LS +L+R++
Sbjct: 716 SPVTVQNYFIVMVPLRKSRGGQF---PILLGSPEDMDLEELIQDLS-----RLQRRSL-- 765
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
+ +R+ VP Y+ AR S F G+ + Y GF N
Sbjct: 766 -------------RHSRQLEVPRPYIAARFSI--------LPAVFHPGNQKQYGGFDNRG 804
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA--- 1253
LE Y L + A + + T ++ S ++PF + +
Sbjct: 805 LEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNPDPQPIVD 847
Query: 1254 SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXX 1430
++ WV G +A + + IV ++ + + + K PR
Sbjct: 848 GEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR------------------ 889
Query: 1431 XXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIP 1610
T LL+ ++ + P HH + P R N P ++ P
Sbjct: 890 -----TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQTPGMLSHP 924
Query: 1611 SLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMN 1790
+P I ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + N
Sbjct: 925 PIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEAN 969
Query: 1791 KHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFW 1970
K KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFW
Sbjct: 970 KPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFW 1029
Query: 1971 RMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRL 2150
RMVWE++S T+VM+T LEE+SRVKCDQYWP+RGT TYG I+VTLL+++ LA + +RT L
Sbjct: 1030 RMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSL 1089
Query: 2151 KMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRT 2330
G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGP++ HCSAG+GRT
Sbjct: 1090 HKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRT 1149
Query: 2331 GAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 2510
G FIVID MLER+R + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEV
Sbjct: 1150 GCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEV 1209
Query: 2511 PASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVP 2687
PA L+ ++ L+Q + ++G+++EF+ L + K ++R A+LP N+ KNR+++ +P
Sbjct: 1210 PARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILP 1269
Query: 2688 YDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPII 2867
Y+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+
Sbjct: 1270 YESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIV 1329
Query: 2868 AMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTV 3047
ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D + RTV
Sbjct: 1330 VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTV 1389
Query: 3048 RQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSII 3227
RQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+
Sbjct: 1390 RQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIV 1449
Query: 3228 LDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1450 LERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1500
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|19743921|ref|NP_570923.1| protein tyrosine phosphatase, receptor
type, sigma isoform 3 precursor; protein tyrosine
phosphatase PTPsigma [Homo sapiens]
Length = 1501
Score = 719 bits (1856), Expect = 0.0
Identities = 435/1138 (38%), Positives = 611/1138 (53%), Gaps = 14/1138 (1%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYM---------HEPGNRMDTEKWKQLP 161
G P N+R EA S ++ + W Q++ ++KY E G D
Sbjct: 513 GQPMNLRAEARSETSITLSWSPPRQES---IIKYELLFREGDHGREVGRTFD-------- 561
Query: 162 VVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV 341
P VV DL + YAF + A + QG + P V + + +N +V
Sbjct: 562 --------PTTSYVVEDLKPNTEYAFRLAA--RSPQGLGAFTPVVRQRTLQSISPKNFKV 611
Query: 342 LWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
SV L+WE+ P N Y + T K N G DVD + + L
Sbjct: 612 KMIMKTSVLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLI 655
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
T+L+PH Y + R G + T+T T ++ V G M+
Sbjct: 656 THLKPHTFYNFVLTNRGSSLGGLQQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMV 709
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKL 881
L P + P+ Y+I++VP S + Q L L
Sbjct: 710 YL-PDGQSPVPVQSYFIVMVPLRKS------------------RGGQFLTPLGSPEDMDL 750
Query: 882 KRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLY 1061
+ ++ + + H +R+ VP Y+ AR S F GD + Y
Sbjct: 751 EELIQDISRLQRRSLRH-----SRQLEVPRPYIAARFSV--------LPPTFHPGDQKQY 797
Query: 1062 DGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSA 1241
GF N LE Y L + A + +K ++ S ++PF + +
Sbjct: 798 GGFDNRGLEPGHRYVLFVLA-----------------VLQKSEPTFAASPFSDPFQLDNP 840
Query: 1242 LRGA---SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTX 1409
++ WV G +A + + IV ++ + + + K PR
Sbjct: 841 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR----------- 889
Query: 1410 XXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYA 1589
T LL+ ++ + P HH + P R N
Sbjct: 890 ------------TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQT 917
Query: 1590 PVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWE 1769
P ++ P + PIA++A H ERL+ N++ E+ESI+ GQ FTWE
Sbjct: 918 PGMLSHPPI---------------PIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWE 962
Query: 1770 HSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLP 1949
HS+ ++NK KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLP
Sbjct: 963 HSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLP 1022
Query: 1950 ETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHY 2129
ETF DFWRMVWE++S TIVM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA +
Sbjct: 1023 ETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATF 1082
Query: 2130 TMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHC 2309
+RT L G E RE++ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HC
Sbjct: 1083 CVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHC 1142
Query: 2310 SAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAV 2489
SAG+GRTG FIVID MLER++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV
Sbjct: 1143 SAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAV 1202
Query: 2490 NSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
G+TEVPA L+ ++ L+Q + ++G+++EF+ L K ++R ANLP N+ KN
Sbjct: 1203 GCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKN 1262
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+++ +PY+S RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +W
Sbjct: 1263 RLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLW 1322
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
E+NS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D
Sbjct: 1323 ENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1382
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
+ RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT V
Sbjct: 1383 DGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGV 1442
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1443 FITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1500
Score = 37.0 bits (84), Expect = 3.2
Identities = 49/205 (23%), Positives = 79/205 (37%), Gaps = 9/205 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSE 525
Query: 357 NSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWTN 527
S+ L+W + PR ++ + +EL G++V + Y+ +
Sbjct: 526 TSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVED 570
Query: 528 LRPHMMYTIHVGVRTLPPGARKYWP 602
L+P+ Y + R+ P G + P
Sbjct: 571 LKPNTEYAFRLAARS-PQGLGAFTP 594
>gi|2118903|pir||A56493 leucocyte common antigen-related protein (LAR)
- rat (fragment)
gi|732919|emb|CAA58495.1| leucocyte common antigen-related protein
(LAR) [Rattus norvegicus]
Length = 1290
Score = 719 bits (1855), Expect = 0.0
Identities = 430/1152 (37%), Positives = 617/1152 (53%), Gaps = 28/1152 (2%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSI----- 173
GPP V VE +++ V W ++ R++ + + P++
Sbjct: 275 GPPRKVEVEPLNSTAVHVSWKLPVPNKQHGQIRGYQVTYVRLENGEPRGQPIIQDVMLAE 334
Query: 174 ----DKENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV 341
+E+ +S L Y+ V A G S P V + T +N RV
Sbjct: 335 AQWRPEESEDYETTISSLTPETTYSITVAAYTTKGDGARSKPKVV--TTTGAVFAKNFRV 392
Query: 342 LWKTSNSVQLTWEYNGPRN--VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREY 515
SV L+WE V F + + G+ +VD
Sbjct: 393 AAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS------------------VEVDGHSMRK 434
Query: 516 LWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQ 695
L +L+P+ Y+ + R G Q +V+I T P + L S+ + G+
Sbjct: 435 LIADLQPNTEYSFVLMNRGSSAGGL----QHLVSIR--TAPDLLPQKPLPASAFIEDGRF 488
Query: 696 MIRLTPATEEYGPISHYWIILVPAN----------YSTEDVVNLDPIELEKATAEKRAQL 845
+ + P ++ + ++I++VP + +ST + + LD +
Sbjct: 489 SLSM-PQVQDPSLVRWFYIVVVPIDRVGGNLLAPRWSTPEELELDEL------------- 534
Query: 846 ARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRN 1025
+A E G++ Q +R R+A YV A++
Sbjct: 535 -------------LEAIEQGEEKQ-------RRRRRQAERLKPYVAAQVD--------EL 566
Query: 1026 NQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEK--LSRMY 1199
+ F +GD + Y GF N PL +L Y+ + A K PM +K S Y
Sbjct: 567 PETFTLGDKKNYRGFYNRPLSPDLSYQCFVLASLKE------------PMDQKRYASSPY 614
Query: 1200 SDSVLTEPFTIKSALRGASQKSSP---WV-GACIAFLVLFSIVGMLICWWLRCNKKSAGR 1367
SD ++ + + A Q+ P WV G +A +++ IV ++ + K+
Sbjct: 615 SDEIVVQ-------VTPAQQQEEPEMLWVTGPVLAVILIILIVIAILLF-----KRKRTH 662
Query: 1368 HPRHGSITKVALTXXXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDL 1547
P + L LL+ S++ P E N+ S
Sbjct: 663 SPSSKDEQSIGLK--------------DSLLAHSSD-------PVEMRRLNYQTPGS--- 698
Query: 1548 YPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQS 1727
+ PS PN + HP +PI +LA++IERL+ N+ F
Sbjct: 699 ------------------SAPSCPNISSMR---DHPPIPITDLADNIERLKANDGLKFSQ 737
Query: 1728 EFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGY 1907
E+ESI+ GQ FTWE+S++++NK KNRYANV AYDHSRV+L++++G PG DYINANY+DGY
Sbjct: 738 EYESIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGY 797
Query: 1908 DKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD 2087
K +YIATQGPLPET DFWRMVWE+++ T+VM+T LEE+SRVKCDQYWP+RGT TYG
Sbjct: 798 RKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETYGL 857
Query: 2088 IEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVK 2267
I+VTL+++V LA YTMRT L G E RE++ Q+ AWPDHGVP++PTP L FL+RVK
Sbjct: 858 IQVTLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVK 917
Query: 2268 TLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTE 2447
NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +R+QR+YMVQTE
Sbjct: 918 ACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTE 977
Query: 2448 EQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSN 2624
+QY+FIH+A+L+A G TEV A L+ H+ L Q P + ++ +++EF+ L K ++
Sbjct: 978 DQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLANSKAHTS 1037
Query: 2625 RCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQA 2804
R ANLP N+ KNR+++ +PY+ RV ++ + G +GSDYINAS++DGY+++ AYIATQ
Sbjct: 1038 RFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQG 1097
Query: 2805 PTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDM 2984
P E+ DFWR +WEHNS II ML + E G+E+C YWP E + VV+PMAEY+M
Sbjct: 1098 PLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNM 1157
Query: 2985 KHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGP 3164
Y LREF+++D + RT+RQF F +WP+ G P T + F+DF+ QVH T QFG GP
Sbjct: 1158 PQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGP 1217
Query: 3165 ITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXX 3344
ITVHC +G GRT VFI LSI+L+RMR E VVD+F TVK LRT+R M+Q +QY
Sbjct: 1218 ITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRA 1277
Query: 3345 XXXXXXXXDNFS 3380
D+++
Sbjct: 1278 ALEYLGSFDHYA 1289
>gi|440973|gb|AAB28877.1| receptor protein tyrosine phosphatase-sigma,
RPTP-sigma [rats, brain, Peptide, 1501 aa]
Length = 1501
Score = 719 bits (1855), Expect = 0.0
Identities = 437/1131 (38%), Positives = 622/1131 (54%), Gaps = 7/1131 (0%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKY--MHEPGNRMDTEKWKQLPVVSIDKE 182
G P N+R EA S ++ + W Q++ V+KY + G+R E +
Sbjct: 513 GQPMNLRAEAKSETSIGLSWSAPRQES---VIKYELLFREGDR-GREVGRTF-------- 560
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+P VV DL + YAF + A + QG + V + +N +V S
Sbjct: 561 DPTTAFVVEDLKPNTEYAFRLAA--RSPQGLGAFTAVVRQRTLQAISPKNFKVKMIMKTS 618
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
V L+WE+ P N Y + T K N G DVD + + L T+L+PH
Sbjct: 619 VLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHT 662
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
Y + R G + +G P V PK D+ G+ ++ P +
Sbjct: 663 FYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGS-----IVVYLPDGQ 715
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
+ +Y+I++VP S PI L +L + LS +L+R++
Sbjct: 716 SPVTVQNYFIVMVPLRKSRGGQF---PILLGSPEDMDLEELIQDLS-----RLQRRSL-- 765
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
+ +R+ VP Y+ AR S F G+ + Y GF N
Sbjct: 766 -------------RHSRQLEVPRPYIAARFSI--------LPAVFHPGNQKQYGGFDNRG 804
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA--- 1253
LE Y L + A + + T ++ S ++PF + +
Sbjct: 805 LEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNPDPQPIVD 847
Query: 1254 SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXX 1430
++ WV G +A + + IV ++ + + + K PR
Sbjct: 848 GEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR------------------ 889
Query: 1431 XXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIP 1610
T LL+ ++ + P HH + P R N P ++ P
Sbjct: 890 -----TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQTPGMLSHP 924
Query: 1611 SLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMN 1790
+P I ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + N
Sbjct: 925 PIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEAN 969
Query: 1791 KHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFW 1970
K KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFW
Sbjct: 970 KPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFW 1029
Query: 1971 RMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRL 2150
RMVWE++S T+VM+T LEE+SRVKCDQYWP+RGT TYG I+VTLL+++ LA + +RT L
Sbjct: 1030 RMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSL 1089
Query: 2151 KMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRT 2330
G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGP++ HCSAG+GRT
Sbjct: 1090 HKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRT 1149
Query: 2331 GAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 2510
G FIVID MLER+R + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEV
Sbjct: 1150 GCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEV 1209
Query: 2511 PASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVP 2687
PA L+ ++ L+Q + ++G+++EF+ L + K ++R A+LP N+ KNR+++ +P
Sbjct: 1210 PARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILP 1269
Query: 2688 YDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPII 2867
Y+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+
Sbjct: 1270 YESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIV 1329
Query: 2868 AMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTV 3047
ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D + RTV
Sbjct: 1330 VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTV 1389
Query: 3048 RQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSII 3227
RQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+
Sbjct: 1390 RQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIV 1449
Query: 3228 LDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1450 LERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1500
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|19743919|ref|NP_002841.2| protein tyrosine phosphatase, receptor
type, sigma isoform 1 precursor; protein tyrosine
phosphatase PTPsigma [Homo sapiens]
gi|50403770|sp|Q13332|PTNS_HUMAN Receptor-type protein-tyrosine
phosphatase S precursor (R-PTP-S) (Protein-tyrosine
phosphatase sigma) (R-PTP-sigma)
Length = 1948
Score = 717 bits (1851), Expect = 0.0
Identities = 419/1055 (39%), Positives = 584/1055 (54%), Gaps = 5/1055 (0%)
Frame = +3
Query: 231 YAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFY 410
Y V A GP S P + +N +V SV L+WE+ P N Y
Sbjct: 1006 YDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEF--PDN---Y 1060
Query: 411 VNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGAR 590
+ T K N G DVD + + L T+L+PH Y + R G
Sbjct: 1061 NSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGL 1109
Query: 591 KYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPAN 770
+ T+T T ++ V G M+ L P + P+ Y+I++VP
Sbjct: 1110 QQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMVYL-PDGQSPVPVQSYFIVMVPLR 1162
Query: 771 YSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRA 950
S + Q L L+ ++ + + H +
Sbjct: 1163 KS------------------RGGQFLTPLGSPEDMDLEELIQDISRLQRRSLRH-----S 1199
Query: 951 RRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAK 1130
R+ VP Y+ AR S F GD + Y GF N LE Y L + A
Sbjct: 1200 RQLEVPRPYIAARFSV--------LPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLA--- 1248
Query: 1131 NDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA---SQKSSPWV-GACIAFL 1298
+ +K ++ S ++PF + + ++ WV G +A +
Sbjct: 1249 --------------VLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVV 1294
Query: 1299 VLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXXETSKLLSTSNEY 1478
+ IV ++ + + + K PR T LL+ ++
Sbjct: 1295 FIICIVIAILLYKNKPDSKRKDSEPR-----------------------TKCLLNNADLA 1331
Query: 1479 GRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPA 1658
+P E N + P S RS P+ P + + +SHP
Sbjct: 1332 PHHPKDPVEMRRIN---------FQTPDSGLRS------PLREPGF----HFESMLSHPP 1372
Query: 1659 VPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSR 1838
+PIA++A H ERL+ N++ E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSR
Sbjct: 1373 IPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSR 1432
Query: 1839 VVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN 2018
V+L +EG G DYINANYVDGY + +YIATQGPLPETF DFWRMVWE++S TIVM+T
Sbjct: 1433 VILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR 1492
Query: 2019 LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQY 2198
LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L G E RE++ Q+
Sbjct: 1493 LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1552
Query: 2199 TAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYD 2378
TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLER++ +
Sbjct: 1553 TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPE 1612
Query: 2379 NTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-P 2555
TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA L+ ++ L+Q
Sbjct: 1613 KTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVE 1672
Query: 2556 SADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADG 2735
+ ++G+++EF+ L K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +G
Sbjct: 1673 PGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEG 1732
Query: 2736 SDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSD 2915
SDYINAS+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ ML + E G+E+C
Sbjct: 1733 SDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQ 1792
Query: 2916 YWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHT 3095
YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G P +
Sbjct: 1793 YWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKS 1852
Query: 3096 ADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTV 3275
+ F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TV
Sbjct: 1853 GEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTV 1912
Query: 3276 KLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
K+LRT+R M+Q ++Y F D+++
Sbjct: 1913 KMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1947
Score = 38.9 bits (89), Expect = 0.85
Identities = 52/220 (23%), Positives = 86/220 (38%), Gaps = 11/220 (5%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 430 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 478
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 479 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSE 538
Query: 357 NSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWTN 527
S+ L+W + PR ++ + +EL G++V + Y+ +
Sbjct: 539 TSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVED 583
Query: 528 LRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPP 641
L+P+ Y + R+ P G + P ++ + P+ PP
Sbjct: 584 LKPNTEYAFRLAARS-PQGLGAFTPVVRQRTLQSKPSAPP 622
>gi|4096822|gb|AAD09360.1| PTPsigma-(brain) [Homo sapiens]
Length = 1502
Score = 717 bits (1850), Expect = 0.0
Identities = 434/1138 (38%), Positives = 610/1138 (53%), Gaps = 14/1138 (1%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYM---------HEPGNRMDTEKWKQLP 161
G P N+R EA S ++ + W Q++ ++KY E G D
Sbjct: 514 GQPMNLRAEARSETSITLSWSPPRQES---IIKYELLFREGDHGREVGRTFD-------- 562
Query: 162 VVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV 341
P VV DL + YAF + A + QG + P V + + +N +V
Sbjct: 563 --------PTTSYVVEDLKPNTEYAFRLAA--RSPQGLGAFTPVVRQRTLQSISPKNFKV 612
Query: 342 LWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
SV L+WE+ P N Y + T K N G DVD + + L
Sbjct: 613 KMIMKTSVLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLI 656
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
T+L+PH Y + R G + T+T T ++ V G M+
Sbjct: 657 THLKPHTFYNFVLTNRGSSLGGLQQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMV 710
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKL 881
L P + P+ Y+I++VP S + Q L L
Sbjct: 711 YL-PDGQSPVPVQSYFIVMVPLRKS------------------RGGQFLTPLGSPEDMDL 751
Query: 882 KRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLY 1061
+ ++ + + H +R+ VP Y+ AR S F GD + Y
Sbjct: 752 EELIQDISRLQRRSLRH-----SRQLEVPRPYIAARFSV--------LPPTFHPGDQKQY 798
Query: 1062 DGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSA 1241
GF N LE Y L + A + +K ++ S ++PF + +
Sbjct: 799 GGFDNRGLEPGHRYVLFVLA-----------------VLQKSEPTFAASPFSDPFQLDNP 841
Query: 1242 LRGA---SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTX 1409
++ WV G +A + + IV ++ + + + K PR
Sbjct: 842 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR----------- 890
Query: 1410 XXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYA 1589
T LL+ ++ + P HH + P R N
Sbjct: 891 ------------TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQT 918
Query: 1590 PVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWE 1769
P ++ P + PIA++A H ERL+ N++ E+ESI+ GQ FTWE
Sbjct: 919 PGMLSHPPI---------------PIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWE 963
Query: 1770 HSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLP 1949
HS+ ++NK KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLP
Sbjct: 964 HSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLP 1023
Query: 1950 ETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHY 2129
ETF DFWRMVWE++S TIVM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA +
Sbjct: 1024 ETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATF 1083
Query: 2130 TMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHC 2309
+RT L G E RE++ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HC
Sbjct: 1084 CVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHC 1143
Query: 2310 SAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAV 2489
SAG+GRTG FIVID MLER++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV
Sbjct: 1144 SAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAV 1203
Query: 2490 NSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
G+TEVPA L+ ++ L+Q + ++G+++EF+ L K ++R ANLP + KN
Sbjct: 1204 GCGNTEVPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCKKFKN 1263
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+++ +PY+S RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +W
Sbjct: 1264 RLVNIMPYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLW 1323
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
E+NS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D
Sbjct: 1324 ENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1383
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
+ RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT V
Sbjct: 1384 DGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGV 1443
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1444 FITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1501
Score = 39.7 bits (91), Expect = 0.50
Identities = 50/206 (24%), Positives = 80/206 (38%), Gaps = 9/206 (4%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDK 179
PP NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PPRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQK 465
Query: 180 EN--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKT 353
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 466 HNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARS 525
Query: 354 SNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWT 524
S+ L+W + PR ++ + +EL G++V + Y+
Sbjct: 526 ETSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVE 570
Query: 525 NLRPHMMYTIHVGVRTLPPGARKYWP 602
+L+P+ Y + R+ P G + P
Sbjct: 571 DLKPNTEYAFRLAARS-PQGLGAFTP 595
>gi|30851400|gb|AAH52462.1| Ptprs protein [Mus musculus]
Length = 1501
Score = 714 bits (1844), Expect = 0.0
Identities = 434/1131 (38%), Positives = 621/1131 (54%), Gaps = 7/1131 (0%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKY--MHEPGNRMDTEKWKQLPVVSIDKE 182
G P N+R EA S ++ + W Q++ V+KY + G+R E +
Sbjct: 513 GQPMNLRAEAKSETSIGLSWSAPRQES---VIKYELLFREGDR-GREVGRTF-------- 560
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+P VV DL + YAF + A + QG + V + +N +V S
Sbjct: 561 DPTTAFVVEDLKPNTEYAFRLAA--RSPQGLGAFTAVVRQRTLQAISPKNFKVKMIMKTS 618
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
V L+WE+ P N Y + T K N G DVD + + L T+L+PH
Sbjct: 619 VLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHT 662
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
Y + R G + +G P V PK D+ G ++ P +
Sbjct: 663 FYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGF-----IVVYLPDGQ 715
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
+ +Y+I++VP S P+ L +L + +S +L+R++
Sbjct: 716 SPVTVQNYFIVMVPLRKSRGGQF---PVLLGSPEDMDLEELIQDIS-----RLQRRSL-- 765
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
+ +R+ VP Y+ AR S F G+ + Y GF N
Sbjct: 766 -------------RHSRQLEVPRPYIAARFSI--------LPAVFHPGNQKQYGGFDNRG 804
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA--- 1253
LE Y L + A + + T ++ S ++PF + +
Sbjct: 805 LEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNPDPQPIVD 847
Query: 1254 SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXX 1430
++ WV G +A + + IV ++ + + + K PR
Sbjct: 848 GEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR------------------ 889
Query: 1431 XXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIP 1610
T LL+ ++ + P HH + P R N P ++ P
Sbjct: 890 -----TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQTPGMLSHP 924
Query: 1611 SLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMN 1790
+P I ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + N
Sbjct: 925 PIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEAN 969
Query: 1791 KHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFW 1970
K KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFW
Sbjct: 970 KPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFW 1029
Query: 1971 RMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRL 2150
RMVWE++S T+VM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L
Sbjct: 1030 RMVWEQRSATVVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSL 1089
Query: 2151 KMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRT 2330
G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRT
Sbjct: 1090 HKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRT 1149
Query: 2331 GAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 2510
G FIVID MLER++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEV
Sbjct: 1150 GCFIVIDAMLERIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEV 1209
Query: 2511 PASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVP 2687
PA L+ ++ L+Q + ++G+++EF+ L + K ++R A+LP N+ KNR+++ +P
Sbjct: 1210 PARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILP 1269
Query: 2688 YDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPII 2867
Y+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+
Sbjct: 1270 YESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIV 1329
Query: 2868 AMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTV 3047
ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D + RTV
Sbjct: 1330 VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTV 1389
Query: 3048 RQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSII 3227
RQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+
Sbjct: 1390 RQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIV 1449
Query: 3228 LDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1450 LERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1500
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|1109792|gb|AAC50299.1| protein tyrosine phosphatase sigma
gi|1586849|prf||2204414A protein Tyr phosphatase
Length = 1948
Score = 714 bits (1844), Expect = 0.0
Identities = 418/1055 (39%), Positives = 582/1055 (54%), Gaps = 5/1055 (0%)
Frame = +3
Query: 231 YAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFY 410
Y V A GP S P + +N +V SV L+WE+ P N Y
Sbjct: 1006 YDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEF--PDN---Y 1060
Query: 411 VNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGAR 590
+ T K N G DVD + + L T+L+PH Y + R G
Sbjct: 1061 NSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGL 1109
Query: 591 KYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPAN 770
+ T+T T ++ V G M+ L P + P+ Y+I++VP
Sbjct: 1110 QQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMVYL-PDGQSPVPVQSYFIVMVPLR 1162
Query: 771 YSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRA 950
S + Q L L+ ++ + H +
Sbjct: 1163 KS------------------RGGQFLTPLGSPEDMDLEELIQDISRLQRRTVRH-----S 1199
Query: 951 RRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAK 1130
R+ VP Y+ AR S F GD + Y GF N LE Y L + A
Sbjct: 1200 RQLEVPRPYIAARFSV--------LPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLA--- 1248
Query: 1131 NDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA---SQKSSPWV-GACIAFL 1298
+ +K ++ S ++PF + + ++ WV G +A +
Sbjct: 1249 --------------VLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVV 1294
Query: 1299 VLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXXETSKLLSTSNEY 1478
+ IV ++ + + + K PR T LL+ ++
Sbjct: 1295 FIICIVIAILLYKNKPDSKRKDSEPR-----------------------TKCLLNNADLA 1331
Query: 1479 GRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPA 1658
+P E N + P S RS P+ P + + +SHP
Sbjct: 1332 PHHPKDPVEMRRIN---------FQTPDSGLRS------PLREPGF----HFESMLSHPP 1372
Query: 1659 VPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSR 1838
+PIA++A H ERL+ N++ E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDH R
Sbjct: 1373 IPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHFR 1432
Query: 1839 VVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN 2018
V+L +EG G DYINANYVDGY + +YIATQGPLPETF DFWRMVWE++S TIVM+T
Sbjct: 1433 VILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR 1492
Query: 2019 LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQY 2198
LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L G E RE++ Q+
Sbjct: 1493 LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1552
Query: 2199 TAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYD 2378
TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLER++ +
Sbjct: 1553 TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPE 1612
Query: 2379 NTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-P 2555
TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA L+ ++ L+Q
Sbjct: 1613 KTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVE 1672
Query: 2556 SADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADG 2735
+ ++G+++EF+ L K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +G
Sbjct: 1673 PGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEG 1732
Query: 2736 SDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSD 2915
SDYINAS+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ ML + E G+E+C
Sbjct: 1733 SDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQ 1792
Query: 2916 YWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHT 3095
YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G P +
Sbjct: 1793 YWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKS 1852
Query: 3096 ADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTV 3275
+ F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TV
Sbjct: 1853 GEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTV 1912
Query: 3276 KLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
K+LRT+R M+Q ++Y F D+++
Sbjct: 1913 KMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1947
Score = 38.9 bits (89), Expect = 0.85
Identities = 52/220 (23%), Positives = 86/220 (38%), Gaps = 11/220 (5%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 430 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 478
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 479 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSE 538
Query: 357 NSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWTN 527
S+ L+W + PR ++ + +EL G++V + Y+ +
Sbjct: 539 TSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVED 583
Query: 528 LRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPP 641
L+P+ Y + R+ P G + P ++ + P+ PP
Sbjct: 584 LKPNTEYAFRLAARS-PQGLGAFTPVVRQRTLQSKPSAPP 622
>gi|46048665|ref|NP_990738.1| protein-tyrosine phosphatase [Gallus
gallus]
gi|2118907|pir||I50212 protein-tyrosine-phosphatase (EC 3.1.3.48) -
chicken
gi|485747|gb|AAA64460.1| protein-tyrosine phosphatase
Length = 1499
Score = 712 bits (1838), Expect = 0.0
Identities = 430/1137 (37%), Positives = 611/1137 (52%), Gaps = 13/1137 (1%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKY--MHEPGNRMDTEKWKQLPVVSIDKE 182
G P N R EA + ++ V+ W S +VKY + + G+ +E
Sbjct: 512 GQPMNFRAEAKTETSIVLSW---SPPRQEIIVKYELLFKEGDH--------------GRE 554
Query: 183 NPKRFA-----VVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLW 347
P+ F V L + Y F + A + G + P V E + + +N +V
Sbjct: 555 VPRNFEPTTSFTVEGLKPNTEYVFRLAA--RSALGLGAFTPEVRERTLQSILPKNFKVKM 612
Query: 348 KTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTN 527
T SV L+WE+ P N Y + T K N G DVD + + L TN
Sbjct: 613 VTKTSVLLSWEF--PEN---YNSPTPYKIQYN-----------GLNVDVDGRTTKKLITN 656
Query: 528 LRPHMMYTIHVGVRTLPPGARKY----WPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQ 695
L+PH Y + R G + W + P +V D+ G
Sbjct: 657 LKPHTFYNFVLMNRGNSMGGLQQNVAAWTAANMLSRKP------EVTHKPDADG-----N 705
Query: 696 MIRLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSK 875
++ + P + + Y+I++VP S + Q L
Sbjct: 706 VVVILPDVKSSVAVQAYYIVVVPLRKS------------------RGGQFLNPLGSPEEM 747
Query: 876 KLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQ 1055
L+ ++ + + H +R+ P Y+ AR + N+ F++GD +
Sbjct: 748 DLEELIQDIARLRRRSLRH-----SRQLDFPKPYIAARF------RSLPNH--FVLGDMK 794
Query: 1056 LYDGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIK 1235
YD F N LE Y + + A + P + + +SD + + +
Sbjct: 795 HYDNFENRALEPGQRYVIFILAVLQE------------PEATFAASPFSDPIQLDNPDPQ 842
Query: 1236 SALRGASQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXX 1412
+ G ++ WV G +A + + IV ++ + + + K PR
Sbjct: 843 PIIDG--EEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR------------ 888
Query: 1413 XXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAP 1592
T LL+ + + P HH + P R N P
Sbjct: 889 -----------TKCLLNNAE------ITP-------HHPKD-------PVEMRRINFQTP 917
Query: 1593 VPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEH 1772
++ P + P++ELA H E L+ N+N E+ESI+ GQ FTWEH
Sbjct: 918 GMLSHPPI---------------PVSELAEHTEHLKANDNLKLSQEYESIDPGQQFTWEH 962
Query: 1773 SSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPE 1952
S+ ++NK KNRYANV AYDHSRV+L +EG G DYINANY+DGY K +YIATQGPLPE
Sbjct: 963 SNLEVNKPKNRYANVIAYDHSRVILLPIEGIVGSDYINANYIDGYRKQNAYIATQGPLPE 1022
Query: 1953 TFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYT 2132
TF DFWRMVWE++S TIVM+T LEE+SR+KCDQYWP RGT TYG I+VTLL+++ LA +
Sbjct: 1023 TFGDFWRMVWEQRSATIVMMTKLEEKSRIKCDQYWPGRGTDTYGMIQVTLLDTIELATFC 1082
Query: 2133 MRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCS 2312
+RT L G E RE++ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCS
Sbjct: 1083 VRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCS 1142
Query: 2313 AGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVN 2492
AG+GRTG FIVID MLER++++ TVDIYG VT +R+QR+YMVQTE+QY FIHDA+L+AV
Sbjct: 1143 AGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVA 1202
Query: 2493 SGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNR 2669
G+TEVPA L+ ++ L+Q + ++G+++EF+ L K ++R ANLP N+ KNR
Sbjct: 1203 CGNTEVPARNLYTYIQKLAQIEVGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNR 1262
Query: 2670 MLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWE 2849
+++ +PY++ RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WE
Sbjct: 1263 LVNIMPYETTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWE 1322
Query: 2850 HNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINT 3029
+NS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D
Sbjct: 1323 NNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARD 1382
Query: 3030 REVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVF 3209
+ RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VF
Sbjct: 1383 GQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVF 1442
Query: 3210 IALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
I LSI+L+RMR E VVD+F TVK+LRT+ M+Q ++Y F D+++
Sbjct: 1443 ITLSIVLERMRYEGVVDIFQTVKMLRTQ-PAMVQTEDEYQFCYQAALEYLGSFDHYA 1498
Score = 37.7 bits (86), Expect = 1.9
Identities = 34/126 (26%), Positives = 48/126 (37%), Gaps = 5/126 (3%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKEN 185
P NV+ S++T ++QW+ + + + V Y EP PV + K N
Sbjct: 416 PRNVQGRMLSSTTMIIQWEEPVEPNGQIRGYRVYYTMEPDQ----------PVSNWQKHN 465
Query: 186 --PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSN 359
V L + Y VLA + GP SDP V N R KT
Sbjct: 466 VDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNFRAEAKTET 525
Query: 360 SVQLTW 377
S+ L+W
Sbjct: 526 SIVLSW 531
>gi|1083478|pir||C54689 protein-tyrosine-phosphatase (EC 3.1.3.48),
receptor type delta, splice form B precursor - mouse
Length = 1894
Score = 710 bits (1833), Expect = 0.0
Identities = 341/618 (55%), Positives = 449/618 (72%), Gaps = 1/618 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + + PV + L N SHP +PI ELA+HIERL+ N+
Sbjct: 1281 ESESRKSSLPNSKEVPSHHPTDPVELRRL--NFQTPGMASHPPIPILELADHIERLKAND 1338
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DY+NA
Sbjct: 1339 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNA 1398
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQG LPETF DFWRM+WE+++ T+VM+T LEERSRVKCDQYWPSRG
Sbjct: 1399 NYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQEA-TVVMMTKLEERSRVKCDQYWPSRG 1457
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T T+G ++VTLL++V L Y +RT L G E R+++ Q+TAWPDHGVP+HPTPFL
Sbjct: 1458 TETHGLVQVTLLDTVELT-YCVRTFALYNNGSSEKRKVRQFQFTAWPDHGVPEHPTPFLA 1516
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+
Sbjct: 1517 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 1576
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L +
Sbjct: 1577 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 1636
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS++DGY+++ A
Sbjct: 1637 SKAHTSRFISANLPCNKFKNRLVNIMPYESGRVCLQPIRGVEGSDYINASFLDGYRQQKA 1696
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 1697 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1756
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 1757 MAEYNMPQYILREFKVTDARDQS-RTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1815
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY
Sbjct: 1816 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 1875
Query: 3327 HFXXXXXXXXXXXXDNFS 3380
F D+++
Sbjct: 1876 QFCYRAALEYLGSFDHYA 1893
Score = 40.4 bits (93), Expect = 0.29
Identities = 64/256 (25%), Positives = 111/256 (43%), Gaps = 20/256 (7%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + S+ + +P N + P ID
Sbjct: 321 PGTPVVTESTATSITLT-WDSGNPGPVSYYI-IQEKPKNSEE-------PYKEIDGIATT 371
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
R++V L+ + Y F V+AV N +GP S+P T TP+ ++++ +S ++
Sbjct: 372 RYSVAG-LSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQTPSSAPRDVQARMLSSTTIL 430
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKH---RE 512
+ W E NG + G+ V +T +++ H + + ++T G V +K +
Sbjct: 431 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITT--IGNLVPQKTYSVKV 487
Query: 513 YLWTNLRPHMMYT-IHVGVRTLPPGAR---KYWPQEVVTITDPTGPPFVDV---PKLVDS 671
+T++ + + I V +T PG K P+ +I PP D +LVD
Sbjct: 488 LAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPREDTIASYELVDR 547
Query: 672 SGTQPGQQMIRLTPAT 719
G Q +Q I + P T
Sbjct: 548 DGDQGEEQRITIEPGT 563
>gi|1083477|pir||D54689 protein-tyrosine-phosphatase (EC 3.1.3.48),
receptor type delta, splice form D precursor - mouse
Length = 1691
Score = 710 bits (1833), Expect = 0.0
Identities = 341/618 (55%), Positives = 449/618 (72%), Gaps = 1/618 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + + PV + L N SHP +PI ELA+HIERL+ N+
Sbjct: 1078 ESESRKSSLPNSKEVPSHHPTDPVELRRL--NFQTPGMASHPPIPILELADHIERLKAND 1135
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DY+NA
Sbjct: 1136 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNA 1195
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQG LPETF DFWRM+WE+++ T+VM+T LEERSRVKCDQYWPSRG
Sbjct: 1196 NYIDGYRKQNAYIATQGSLPETFGDFWRMIWEQEA-TVVMMTKLEERSRVKCDQYWPSRG 1254
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T T+G ++VTLL++V L Y +RT L G E R+++ Q+TAWPDHGVP+HPTPFL
Sbjct: 1255 TETHGLVQVTLLDTVELT-YCVRTFALYNNGSSEKRKVRQFQFTAWPDHGVPEHPTPFLA 1313
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+
Sbjct: 1314 FLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 1373
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L +
Sbjct: 1374 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 1433
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS++DGY+++ A
Sbjct: 1434 SKAHTSRFISANLPCNKFKNRLVNIMPYESGRVCLQPIRGVEGSDYINASFLDGYRQQKA 1493
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 1494 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1553
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 1554 MAEYNMPQYILREFKVTDARDQS-RTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1612
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY
Sbjct: 1613 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 1672
Query: 3327 HFXXXXXXXXXXXXDNFS 3380
F D+++
Sbjct: 1673 QFCYRAALEYLGSFDHYA 1690
Score = 43.5 bits (101), Expect = 0.034
Identities = 65/256 (25%), Positives = 112/256 (43%), Gaps = 20/256 (7%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + S+ + H+P N + P ID
Sbjct: 118 PGTPVVTESTATSITLT-WDSGNPGPVSYYI-IQHKPKNSEE-------PYKEIDGIATT 168
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
R++V L+ + Y F V+AV N +GP S+P T TP+ ++++ +S ++
Sbjct: 169 RYSVAG-LSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQTPSSAPRDVQARMLSSTTIL 227
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKH---RE 512
+ W E NG + G+ V +T +++ H + + ++T G V +K +
Sbjct: 228 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITT--IGNLVPQKTYSVKV 284
Query: 513 YLWTNLRPHMMYT-IHVGVRTLPPGAR---KYWPQEVVTITDPTGPPFVDV---PKLVDS 671
+T++ + + I V +T PG K P+ +I PP D +LVD
Sbjct: 285 LAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVDR 344
Query: 672 SGTQPGQQMIRLTPAT 719
G Q +Q I + P T
Sbjct: 345 DGDQGEEQRITIEPGT 360
>gi|1083771|pir||A48758 protein-tyrosine-phosphatase (EC 3.1.3.48),
receptor-linked form P1 precursor - rat
Length = 1496
Score = 708 bits (1828), Expect = 0.0
Identities = 434/1115 (38%), Positives = 614/1115 (54%), Gaps = 7/1115 (0%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKY--MHEPGNRMDTEKWKQLPVVSIDKE 182
G P N+R EA S ++ + W Q++ V+KY + G+R E +
Sbjct: 511 GQPMNLRAEAKSETSIGLSWSAPRQES---VIKYELLFREGDR-GREVGRTF-------- 558
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+P VV DL + YAF + A + QG + V + +N +V S
Sbjct: 559 DPTTAFVVEDLKPNTEYAFRLAA--RSPQGLGAFTAVVRQRTLQAISPKNFKVKMIMKTS 616
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
V L+WE+ P N Y + T K N G DVD + + L T+L+PH
Sbjct: 617 VLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHT 660
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
Y + R G + +G P V PK D+ G+ ++ P +
Sbjct: 661 FYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGS-----IVVYLPDGQ 713
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
+ +Y+I++VP S PI L +L + LS +L+R++
Sbjct: 714 SPVTVQNYFIVMVPLRKSRGGQF---PILLPSPEDMDLEELIQDLS-----RLQRRSL-- 763
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
+ +R+ VP Y+ AR S F G+ + Y GF N
Sbjct: 764 -------------RHSRQLEVPRPYIAARFSI--------LPAVFHPGNQKQYGGFDNRG 802
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA--- 1253
LE Y L + A + + T ++ S ++PF + +
Sbjct: 803 LEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNPDPQPIVD 845
Query: 1254 SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXX 1430
++ WV G +A + + IV ++ + + + K PR
Sbjct: 846 GEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR------------------ 887
Query: 1431 XXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIP 1610
T LL+ ++ + P HH + P R N P ++ P
Sbjct: 888 -----TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQTPGMLSHP 922
Query: 1611 SLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMN 1790
+P I ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + N
Sbjct: 923 PIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEAN 967
Query: 1791 KHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFW 1970
K KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFW
Sbjct: 968 KPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFW 1027
Query: 1971 RMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRL 2150
RMVWE++S T+VM+T LEE+SRVKCDQYWP+RGT TYG I+VTLL+++ LA + +RT L
Sbjct: 1028 RMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSL 1087
Query: 2151 KMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRT 2330
G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGP++ HCSAG+GRT
Sbjct: 1088 HKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRT 1147
Query: 2331 GAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 2510
G FIVID MLER+R + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEV
Sbjct: 1148 GCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEV 1207
Query: 2511 PASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVP 2687
PA L+ ++ L+Q + ++G+++EF+ L + T A+LP N+ KNR+++ +P
Sbjct: 1208 PARSLYTYIQKLAQVEPGEHVTGMELEFKRLAAPRHTLRDSFTASLPCNKFKNRLVNILP 1267
Query: 2688 YDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPII 2867
Y+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+
Sbjct: 1268 YESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIV 1327
Query: 2868 AMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTV 3047
ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D + RTV
Sbjct: 1328 VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPEYILREFKVTDARDGQSRTV 1387
Query: 3048 RQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSII 3227
RQ F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+
Sbjct: 1388 RQ--FTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIV 1445
Query: 3228 LDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF 3332
L+RMR E VVD+F TVK+LRT+R M+Q ++Y F
Sbjct: 1446 LERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQF 1480
Score = 214 bits (544), Expect = 1e-53
Identities = 112/283 (39%), Positives = 160/283 (55%), Gaps = 8/283 (2%)
Frame = +3
Query: 1659 VPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKNRYANVA 1820
VP L +I++L + G + EF+ + +H + +A + NK KNR N+
Sbjct: 1207 VPARSLYTYIQKLAQVEPGEHVTGMELEFKRLAAPRHTLRDSFTASLPCNKFKNRLVNIL 1266
Query: 1821 AYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVT 2000
Y+ SRV L + G G DYINA+++DGY + ++YIATQGPL ET DFWR +WE S
Sbjct: 1267 PYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTI 1326
Query: 2001 IVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVRE 2180
+VMLT L E R KC QYWP+ +A Y V + ++ Y +R ++ + + R
Sbjct: 1327 VVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPEYILREFKVTDARDGQSRT 1386
Query: 2181 IKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDC 2354
++ Q+T WP+ G P F+ F+ +V GPI HCSAG+GRTG FI +
Sbjct: 1387 VR--QFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSI 1444
Query: 2355 MLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLD 2483
+LER+RY+ VDI+ V LR QR MVQTE++Y F A L+
Sbjct: 1445 VLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALE 1487
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 415 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 463
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 464 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 523
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 524 TSIGLSW 530
>gi|47223076|emb|CAG07163.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 582
Score = 708 bits (1827), Expect = 0.0
Identities = 329/578 (56%), Positives = 432/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +P+ +LA+HIERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYD
Sbjct: 4 HPPIPVIDLADHIERLKANDGLRFSQEYESIDPGQQFTWENSNMEVNKPKNRYANVIAYD 63
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRVVL++V+G PG DYINANY+DGY K +YIATQGPLPET SDFWRMVWE++S TIVM
Sbjct: 64 HSRVVLTSVDGVPGSDYINANYIDGYRKQNAYIATQGPLPETLSDFWRMVWEQRSNTIVM 123
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWPSRG+ TYG I+VT+L++V LA Y++RT L G E RE++
Sbjct: 124 MTRLEEKSRVKCDQYWPSRGSETYGMIQVTMLDTVELATYSVRTFALYKNGSNEKREVRQ 183
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVKT NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 184 FQFMAWPDHGVPEYPTPILAFLRRVKTCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERM 243
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +RAQR+YMVQTE+QYIFIH+A+L+A G+TEVPA L+ H+ L+
Sbjct: 244 KHEKTVDIYGHVTCMRAQRNYMVQTEDQYIFIHEALLEAATCGNTEVPARNLYAHIQKLT 303
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P+ + ++ +++EF+ L K ++R ANLP N+ KNR+++ +P++S RV ++ + G
Sbjct: 304 QPPTGETVTAMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPFESTRVCLQPIRG 363
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E+
Sbjct: 364 VEGSDYINASCIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREK 423
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 424 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 483
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 484 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDLF 543
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 544 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 581
>gi|47219585|emb|CAG02291.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1751
Score = 707 bits (1826), Expect = 0.0
Identities = 339/618 (54%), Positives = 440/618 (70%), Gaps = 25/618 (4%)
Frame = +3
Query: 1554 LPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEF 1733
LP S + PV + L N SHP +P+ ELA+H+ERL+ N+N F E+
Sbjct: 1119 LPNSKELPLHHPTDPVELRRL--NFQTPGMASHPPIPVTELADHLERLKANDNLKFSQEY 1176
Query: 1734 ESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDK 1913
ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS ++G PG DYINANY+DGY K
Sbjct: 1177 ESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIDGVPGSDYINANYIDGYRK 1236
Query: 1914 PRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIE 2093
+YIATQG LPETF +FWRM+WE++S IVM+T LEERSRVKCDQYWP+RGT TYG I+
Sbjct: 1237 QNAYIATQGALPETFGEFWRMIWEQRSANIVMMTKLEERSRVKCDQYWPTRGTETYGLIQ 1296
Query: 2094 VTLLESVHLAHYTMRTMRLKMVGEPEV------------------------REIKHLQYT 2201
VTLL++V LA Y +RT L VG + RE++ Q+T
Sbjct: 1297 VTLLDTVELATYCVRTFALFKVGSASISRYSEGSEADHSPVLLLQNGSSEKREVRQFQFT 1356
Query: 2202 AWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDN 2381
AWPDHGVP+HPT FL FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER++++
Sbjct: 1357 AWPDHGVPEHPTLFLAFLRRVKACNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEK 1416
Query: 2382 TVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PS 2558
TVDIYG VT +RAQR+YMVQTE+QY+FIHDA+L+AVN G+TEVPA L+ ++ L+Q
Sbjct: 1417 TVDIYGHVTLMRAQRNYMVQTEDQYVFIHDALLEAVNCGTTEVPARNLYAYIQKLTQIEG 1476
Query: 2559 ADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGS 2738
+ +SG+++EF+ L K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GS
Sbjct: 1477 GENVSGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGS 1536
Query: 2739 DYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDY 2918
DYINAS+IDGY+++ AYIATQ P ET DFWR +WEHNS I+ ML + E G+E+C Y
Sbjct: 1537 DYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQY 1596
Query: 2919 WPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTA 3098
WP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G P +
Sbjct: 1597 WPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSG 1656
Query: 3099 DHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVK 3278
+ F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK
Sbjct: 1657 EGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVK 1716
Query: 3279 LLRTERQNMIQEPEQYHF 3332
+LRT+R M+Q +QY F
Sbjct: 1717 MLRTQRPAMVQTEDQYQF 1734
Score = 224 bits (570), Expect = 1e-56
Identities = 117/287 (40%), Positives = 166/287 (57%), Gaps = 8/287 (2%)
Frame = +3
Query: 1659 VPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKNRYANVA 1820
VP L +I++L N +G + EF+ + + T SA++ NK KNR N+
Sbjct: 1459 VPARNLYAYIQKLTQIEGGENVSGMELEFKRLANTKAHTSRFISANLPCNKFKNRLVNIM 1518
Query: 1821 AYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVT 2000
Y+ +RV L + G G DYINA+++DGY + ++YIATQGPL ET DFWRM+WE S
Sbjct: 1519 PYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWEHNSTI 1578
Query: 2001 IVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVRE 2180
+VMLT L E R KC QYWP+ +A Y V + ++ Y +R ++ + + R
Sbjct: 1579 VVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT 1638
Query: 2181 IKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDC 2354
++ Q+T WP+ GVP F+ F+ +V GPI HCSAG+GRTG FI +
Sbjct: 1639 VRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSI 1698
Query: 2355 MLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNS 2495
+LER+RY+ VDI+ V LR QR MVQTE+QY F + A L+ + S
Sbjct: 1699 VLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRAGLEYLGS 1745
Score = 39.3 bits (90), Expect = 0.65
Identities = 45/193 (23%), Positives = 76/193 (39%), Gaps = 7/193 (3%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFVVKYM--HEPGNRMDTEKWKQLPVVSIDKENP 188
P VR S++TAV+ WD E ++A+ ++ Y + + W++ V
Sbjct: 191 PRQVRGHMMSSTTAVIHWD-EPEEANGQIMGYRVYYTMDSSQHVNLWEKQIV------RG 243
Query: 189 KRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQ 368
+F + L +K Y VLA + GP S ++ + + K+ S+
Sbjct: 244 SKFVTIQGLIPNKTYYIKVLAYTSVGDGPLSPDLQIITKTGVPSQPTDFKAEAKSETSIL 303
Query: 369 LTWEYNGPRNVGFYVNHTG-----RKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLR 533
L+W P G TG RK + + +EK +S E YL +L+
Sbjct: 304 LSW--IAPAQTGQENQITGYELVYRK---SDDTEEKRISF--------EPTTTYLLKDLK 350
Query: 534 PHMMYTIHVGVRT 572
P YT + R+
Sbjct: 351 PFTTYTFRLAARS 363
>gi|310202|gb|AAA75407.1| receptor-linked protein tyrosine phosphatase
Length = 1495
Score = 706 bits (1822), Expect = 0.0
Identities = 435/1115 (39%), Positives = 611/1115 (54%), Gaps = 7/1115 (0%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKY--MHEPGNRMDTEKWKQLPVVSIDKE 182
G P N+R EA S ++ + W Q++ V+KY + G+R E +
Sbjct: 511 GQPMNLRAEAKSETSIGLSWSAPRQES---VIKYELLFREGDR-GREVGRTF-------- 558
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+P VV DL + YAF + A + QG + V + +N +V S
Sbjct: 559 DPTTAFVVEDLKPNTEYAFRLAA--RSPQGLGAFTAVVRQRTLQAISPKNFKVKMIMKTS 616
Query: 363 VQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHM 542
V L+WE+ P N Y + T K N G DVD + + L T+L+PH
Sbjct: 617 VLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHT 660
Query: 543 MYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATE 722
Y + R G + +G P V PK D+ G+ ++ P +
Sbjct: 661 FYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGS-----IVVYLPDGQ 713
Query: 723 EYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEV 902
+ +Y+I++VP S PI L +L + LS
Sbjct: 714 SPVTVQNYFIVMVPLRKSRGGQF---PILLPSPEDMDLEELIQDLS-------------- 756
Query: 903 GDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYP 1082
QS+ H +R+ VP Y+ AR S F G+ + Y GF N
Sbjct: 757 --RLQSSLRH-----SRQLEVPRPYIAARFSI--------LPAVFHPGNQKQYGGFDNRG 801
Query: 1083 LEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA--- 1253
LE Y L + A + + T ++ S ++PF + +
Sbjct: 802 LEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNPDPQPIVD 844
Query: 1254 SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXX 1430
++ WV G +A + + IV ++ + + + K PR
Sbjct: 845 GEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR------------------ 886
Query: 1431 XXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIP 1610
T LL+ ++ + P HH + P R N P ++ P
Sbjct: 887 -----TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQTPGMLSHP 921
Query: 1611 SLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMN 1790
+P I ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + N
Sbjct: 922 PIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEAN 966
Query: 1791 KHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFW 1970
K KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFW
Sbjct: 967 KPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFW 1026
Query: 1971 RMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRL 2150
RMVWE++S T+VM+T LEE+SRVKCDQYWP+RGT TYG I+VTLL+++ LA + +RT L
Sbjct: 1027 RMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSL 1086
Query: 2151 KMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRT 2330
G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGP++ HCSAG+GRT
Sbjct: 1087 HKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHCSAGVGRT 1146
Query: 2331 GAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 2510
G FIVID MLER+R + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEV
Sbjct: 1147 GCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEV 1206
Query: 2511 PASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVP 2687
PA L+ ++ L+Q + ++G+++EF+ L + T A+LP N+ KNR+++ +P
Sbjct: 1207 PARSLYTYIQKLAQVEPGEHVTGMELEFKRLAAPRHTLRDSFTASLPCNKFKNRLVNILP 1266
Query: 2688 YDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPII 2867
Y+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+
Sbjct: 1267 YESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIV 1326
Query: 2868 AMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTV 3047
ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D + RTV
Sbjct: 1327 VMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPEYILREFKVTDARDGQSRTV 1386
Query: 3048 RQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSII 3227
RQ F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+
Sbjct: 1387 RQ--FTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIV 1444
Query: 3228 LDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF 3332
L+RMR E VVD+F TVK+LRT+R M+Q ++Y F
Sbjct: 1445 LERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQF 1479
Score = 214 bits (544), Expect = 1e-53
Identities = 112/283 (39%), Positives = 160/283 (55%), Gaps = 8/283 (2%)
Frame = +3
Query: 1659 VPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKNRYANVA 1820
VP L +I++L + G + EF+ + +H + +A + NK KNR N+
Sbjct: 1206 VPARSLYTYIQKLAQVEPGEHVTGMELEFKRLAAPRHTLRDSFTASLPCNKFKNRLVNIL 1265
Query: 1821 AYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVT 2000
Y+ SRV L + G G DYINA+++DGY + ++YIATQGPL ET DFWR +WE S
Sbjct: 1266 PYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTI 1325
Query: 2001 IVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVRE 2180
+VMLT L E R KC QYWP+ +A Y V + ++ Y +R ++ + + R
Sbjct: 1326 VVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPEYILREFKVTDARDGQSRT 1385
Query: 2181 IKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDC 2354
++ Q+T WP+ G P F+ F+ +V GPI HCSAG+GRTG FI +
Sbjct: 1386 VR--QFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSI 1443
Query: 2355 MLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLD 2483
+LER+RY+ VDI+ V LR QR MVQTE++Y F A L+
Sbjct: 1444 VLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALE 1486
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 415 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 463
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 464 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 523
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 524 TSIGLSW 530
>gi|47213552|emb|CAF91826.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1209
Score = 706 bits (1821), Expect = 0.0
Identities = 329/586 (56%), Positives = 438/586 (74%), Gaps = 1/586 (0%)
Frame = +3
Query: 1557 PTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFE 1736
P S + S+ + PV + + N SHP VPI+ELA+HIERL+ N+N F E+E
Sbjct: 541 PCSKAMSSHHPTDPVELRRI--NFQTPGMASHPPVPISELADHIERLKANDNLKFSQEYE 598
Query: 1737 SIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKP 1916
S++ GQ FTWE+S+ ++NK KNRYANV AYDHSRV+LS+++G PG DYINANY+DGY +
Sbjct: 599 SVDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVMLSSIDGVPGSDYINANYIDGYRRQ 658
Query: 1917 RSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEV 2096
+YIATQG LPETF DFWRMVWE+ + I+M+T LEE+SRVKCDQYWP+RGT TYG I+V
Sbjct: 659 NAYIATQGSLPETFGDFWRMVWEQHTANIIMMTKLEEKSRVKCDQYWPTRGTETYGLIQV 718
Query: 2097 TLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLN 2276
TLL++V LA Y++RT L G E RE++H Q+TAWPDHGVP+HPTPFL FL+RVK N
Sbjct: 719 TLLDTVELATYSVRTFALYKSGSNEKREVRHFQFTAWPDHGVPEHPTPFLAFLRRVKACN 778
Query: 2277 PNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQY 2456
P DAGP+I HCSAG+GRTG FIVID M ER++++ T+D+YG VT +R+QR+YMVQTE+QY
Sbjct: 779 PPDAGPMIVHCSAGVGRTGCFIVIDAMTERIKHEKTLDVYGHVTLMRSQRNYMVQTEDQY 838
Query: 2457 IFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCT 2633
IFIHDA+L+AV G+TEVPA L+ ++ L+Q + ++G+++EF+ L + K ++R
Sbjct: 839 IFIHDALLEAVTCGNTEVPARNLYSYIQRLTQIEPGENVTGMELEFKRLASAKAHTSRFV 898
Query: 2634 VANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTN 2813
ANL N+ KNR+++ +PY++ RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P
Sbjct: 899 SANLSCNKFKNRLVNIMPYETTRVSLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLA 958
Query: 2814 ETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHY 2993
ET D+WR +WEHNS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y
Sbjct: 959 ETTEDYWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQY 1018
Query: 2994 HLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITV 3173
LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GPITV
Sbjct: 1019 ILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITV 1078
Query: 3174 HCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQ 3311
HC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R +Q
Sbjct: 1079 HCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPATVQ 1124
Score = 218 bits (555), Expect = 8e-55
Identities = 115/299 (38%), Positives = 169/299 (56%), Gaps = 8/299 (2%)
Frame = +3
Query: 1641 TVSHPAVPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKN 1802
T + VP L ++I+RL N G + EF+ + + + T SA++ NK KN
Sbjct: 850 TCGNTEVPARNLYSYIQRLTQIEPGENVTGMELEFKRLASAKAHTSRFVSANLSCNKFKN 909
Query: 1803 RYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVW 1982
R N+ Y+ +RV L + G G DYINA+++DGY + ++YIATQGPL ET D+WRM+W
Sbjct: 910 RLVNIMPYETTRVSLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDYWRMLW 969
Query: 1983 EEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVG 2162
E S +VMLT L E R KC QYWP+ +A Y V + ++ Y +R ++
Sbjct: 970 EHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1029
Query: 2163 EPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGA 2336
+ + R ++ Q+T WP+ GVP F+ F+ +V GPI HCSAG+GRTG
Sbjct: 1030 DGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGV 1089
Query: 2337 FIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVP 2513
FI + +LER+RY+ VDI+ V LR QR VQTE + +H +L ++ + S +P
Sbjct: 1090 FITLSIVLERMRYEGVVDIFQTVKMLRTQRPATVQTEVSRLLLH-FLLPSLQATSLSLP 1147
Score = 183 bits (464), Expect = 3e-44
Identities = 89/232 (38%), Positives = 133/232 (56%)
Frame = +3
Query: 2637 ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNE 2816
+NL VN+PKNR + + YD +RV++ + G GSDYINA++IDGY+ + AYIATQ E
Sbjct: 611 SNLEVNKPKNRYANVIAYDHSRVMLSSIDGVPGSDYINANYIDGYRRQNAYIATQGSLPE 670
Query: 2817 TAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYH 2996
T DFWR +WE ++ I M+ + E+ + +C YWP G++ V + ++ Y
Sbjct: 671 TFGDFWRMVWEQHTANIIMMTKLEEKSRVKCDQYWPTRGTETYGLIQVTLLDTVELATYS 730
Query: 2997 LREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVH 3176
+R F + + E R VR F F WPD G P FL F+ +V GP+ VH
Sbjct: 731 VRTFALYKSGSNEKREVRHFQFTAWPDHGVPEHPTPFLAFLRRVKACNPPDA--GPMIVH 788
Query: 3177 CCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF 3332
C +G GRT FI + + +R++ E +DV+ V L+R++R M+Q +QY F
Sbjct: 789 CSAGVGRTGCFIVIDAMTERIKHEKTLDVYGHVTLMRSQRNYMVQTEDQYIF 840
>gi|3702284|gb|AAC62834.1| PTPsigma [AA 524- 1926] [Homo sapiens]
Length = 1399
Score = 706 bits (1821), Expect = 0.0
Identities = 416/1032 (40%), Positives = 573/1032 (55%), Gaps = 5/1032 (0%)
Frame = +3
Query: 231 YAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFY 410
Y V A GP S P + +N +V SV L+WE+ P N Y
Sbjct: 483 YDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEF--PDN---Y 537
Query: 411 VNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGAR 590
+ T K N G DVD + + L T+L+PH Y + R G
Sbjct: 538 NSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGL 586
Query: 591 KYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPAN 770
+ T+T T ++ V G M+ L P + P+ Y+I++VP
Sbjct: 587 QQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMVYL-PDGQSPVPVQSYFIVMVPLR 639
Query: 771 YSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRA 950
S + Q L L+ ++ + + H +
Sbjct: 640 KS------------------RGGQFLTPLGSPEDMDLEELIQDISRLQRRSLRH-----S 676
Query: 951 RRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAK 1130
R+ VP Y+ AR S F GD + Y GF N LE Y L + A
Sbjct: 677 RQLEVPRPYIAARFSV--------LPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLA--- 725
Query: 1131 NDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA---SQKSSPWV-GACIAFL 1298
+ +K ++ S ++PF + + ++ WV G +A +
Sbjct: 726 --------------VLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVV 771
Query: 1299 VLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXXETSKLLSTSNEY 1478
+ IV ++ + K PR T LL+ ++
Sbjct: 772 FIICIVIAILLY----KNKRKDSEPR-----------------------TKCLLNNADLA 804
Query: 1479 GRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPA 1658
+P E N + P S RS P+ P + + +SHP
Sbjct: 805 PHHPKDPVEMRRIN---------FQTPDSGLRS------PLREPGF----HFESMLSHPP 845
Query: 1659 VPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSR 1838
+PIA++A H ERL+ N++ E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSR
Sbjct: 846 IPIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSR 905
Query: 1839 VVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN 2018
V+L +EG G DYINANYVDGY +YIATQGPLPETF DFWRMVWE++S TIVM+T
Sbjct: 906 VILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR 965
Query: 2019 LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQY 2198
LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L G E RE++ Q+
Sbjct: 966 LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1025
Query: 2199 TAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYD 2378
TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLER++ +
Sbjct: 1026 TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPE 1085
Query: 2379 NTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-P 2555
TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA L+ ++ L+Q
Sbjct: 1086 KTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVE 1145
Query: 2556 SADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADG 2735
+ ++G+++EF+ L K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +G
Sbjct: 1146 PGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEG 1205
Query: 2736 SDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSD 2915
SDYINAS+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ ML + E G+E+C
Sbjct: 1206 SDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQ 1265
Query: 2916 YWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHT 3095
YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G P +
Sbjct: 1266 YWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKS 1325
Query: 3096 ADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTV 3275
+ F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TV
Sbjct: 1326 GEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTV 1385
Query: 3276 KLLRTERQNMIQ 3311
K+LRT+R M+Q
Sbjct: 1386 KMLRTQRPAMVQ 1397
Score = 212 bits (540), Expect = 4e-53
Identities = 110/271 (40%), Positives = 155/271 (56%), Gaps = 8/271 (2%)
Frame = +3
Query: 1659 VPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKNRYANVA 1820
VP L +I++L + G + EF+ + + T SA++ NK KNR N+
Sbjct: 1129 VPARSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIM 1188
Query: 1821 AYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVT 2000
Y+ +RV L + G G DYINA+++DGY + ++YIATQGPL ET DFWRM+WE S
Sbjct: 1189 PYESTRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTI 1248
Query: 2001 IVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVRE 2180
+VMLT L E R KC QYWP+ +A Y V + ++ Y +R ++ + + R
Sbjct: 1249 VVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT 1308
Query: 2181 IKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDC 2354
++ Q+T WP+ GVP F+ F+ +V GPI HCSAG+GRTG FI +
Sbjct: 1309 VRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSI 1368
Query: 2355 MLERLRYDNTVDIYGCVTALRAQRSYMVQTE 2447
+LER+RY+ VDI+ V LR QR MVQTE
Sbjct: 1369 VLERMRYEGVVDIFQTVKMLRTQRPAMVQTE 1399
Score = 191 bits (486), Expect = 8e-47
Identities = 95/232 (40%), Positives = 135/232 (57%)
Frame = +3
Query: 2637 ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNE 2816
+NL VN+PKNR + + YD +RVI++ + G GSDYINA+++DGY+ + AYIATQ P E
Sbjct: 884 SNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRCQNAYIATQGPLPE 943
Query: 2817 TAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYH 2996
T DFWR +WE S I M+ R E+ + +C YWP G + V + ++ +
Sbjct: 944 TFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFC 1003
Query: 2997 LREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVH 3176
+R F + + E R VRQF F WPD G P FL F+ +V GPI VH
Sbjct: 1004 VRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDA--GPIVVH 1061
Query: 3177 CCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF 3332
C +G GRT FI + +L+R++ E VDV+ V L+R++R M+Q +QY F
Sbjct: 1062 CSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSF 1113
>gi|9507011|ref|NP_062013.1| protein tyrosine phosphatase, receptor
type, D [Rattus norvegicus]
gi|205135|gb|AAC37656.1| leukocyte common antigen-related phosphatase
Length = 1863
Score = 706 bits (1821), Expect = 0.0
Identities = 431/1138 (37%), Positives = 616/1138 (53%), Gaps = 12/1138 (1%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQW-DFESQKADSFVVKYMHE------PGNRMDTEKWKQLP 161
++GP NV S + +++W + + ++KY PG +TE
Sbjct: 866 ILGPAGNV-----SAGSVILRWLPPVPAEGNGAIIKYTVSVREAGTPGPATETE------ 914
Query: 162 VVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV 341
+ + + + + L Y V A GP S PP +N +V
Sbjct: 915 LAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFS-PPLRYRLARDPVSPKNFKV 973
Query: 342 LWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
SV L+WE+ P N Y + T K N G DVD + + L
Sbjct: 974 KMIMKTSVLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLI 1017
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
T+L+PH Y + R G + +G P V PK D+ G+ ++
Sbjct: 1018 THLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGS-----IV 1070
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKL 881
P + + +Y+I++VP S PI L +L + LS +L
Sbjct: 1071 VYLPDGQSPVTVQNYFIVMVPLRKSRGGQF---PILLGSPEDMDLEELIQDLS-----RL 1122
Query: 882 KRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLY 1061
+R++ + +R+ VP Y+ AR S F G+ + Y
Sbjct: 1123 QRRSL---------------RHSRQLEVPRPYIAARFSI--------LPAVFHPGNQKQY 1159
Query: 1062 DGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSA 1241
GF N LE Y L + A + + T ++ S ++PF + +
Sbjct: 1160 GGFDNRGLEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNP 1202
Query: 1242 LRGA---SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTX 1409
++ WV G +A + + IV ++ + + + K PR
Sbjct: 1203 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR----------- 1251
Query: 1410 XXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYA 1589
T LL+ ++ + P HH + P R N
Sbjct: 1252 ------------TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQT 1279
Query: 1590 PVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWE 1769
P ++ P +P I ++A H+ERL+ N++ E+ESI+ GQ FTWE
Sbjct: 1280 PGMLSHPPIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWE 1324
Query: 1770 HSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLP 1949
HS+ + NK KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLP
Sbjct: 1325 HSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLP 1384
Query: 1950 ETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHY 2129
ETF DFWRMVWE++S T+VM+T LEE+SRVKCDQYWP+RGT TYG I+VTLL+++ LA +
Sbjct: 1385 ETFGDFWRMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATF 1444
Query: 2130 TMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHC 2309
+RT L G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGP++ HC
Sbjct: 1445 CVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHC 1504
Query: 2310 SAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAV 2489
SAG+GRTG FIVID MLER+R + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV
Sbjct: 1505 SAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAV 1564
Query: 2490 NSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
G+TEVPA L+ ++ L+Q + ++G+++EF+ L + K ++R A+LP N+ KN
Sbjct: 1565 GCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKN 1624
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+++ +PY+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+W
Sbjct: 1625 RLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALW 1684
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
E+NS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D
Sbjct: 1685 ENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1744
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
+ RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT V
Sbjct: 1745 DGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGV 1804
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1805 FITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1862
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|19743923|ref|NP_570924.1| protein tyrosine phosphatase, receptor
type, sigma isoform 2 precursor; protein tyrosine
phosphatase PTPsigma [Homo sapiens]
Length = 1910
Score = 704 bits (1817), Expect = 0.0
Identities = 415/1055 (39%), Positives = 578/1055 (54%), Gaps = 5/1055 (0%)
Frame = +3
Query: 231 YAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQLTWEYNGPRNVGFY 410
Y V A GP S P + +N +V SV L+WE+ P N Y
Sbjct: 984 YDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVLLSWEF--PDN---Y 1038
Query: 411 VNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGAR 590
+ T K N G DVD + + L T+L+PH Y + R G
Sbjct: 1039 NSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHTFYNFVLTNRGSSLGGL 1087
Query: 591 KYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPAN 770
+ T+T T ++ V G M+ L P + P+ Y+I++VP
Sbjct: 1088 QQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMVYL-PDGQSPVPVQSYFIVMVPLR 1140
Query: 771 YSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRA 950
S + Q L L+ ++ + + H +
Sbjct: 1141 KS------------------RGGQFLTPLGSPEDMDLEELIQDISRLQRRSLRH-----S 1177
Query: 951 RRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAK 1130
R+ VP Y+ AR S F GD + Y GF N LE Y L + A
Sbjct: 1178 RQLEVPRPYIAARFSV--------LPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLA--- 1226
Query: 1131 NDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA---SQKSSPWV-GACIAFL 1298
+ +K ++ S ++PF + + ++ WV G +A +
Sbjct: 1227 --------------VLQKSEPTFAASPFSDPFQLDNPDPQPIVDGEEGLIWVIGPVLAVV 1272
Query: 1299 VLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXXETSKLLSTSNEY 1478
+ IV ++ + + + K PR T LL+ ++
Sbjct: 1273 FIICIVIAILLYKNKPDSKRKDSEPR-----------------------TKCLLNNAD-- 1307
Query: 1479 GRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPA 1658
+ P HH + P R N P ++ P +
Sbjct: 1308 ----LAP-------HHPKD-------PVEMRRINFQTPGMLSHPPI-------------- 1335
Query: 1659 VPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSR 1838
PIA++A H ERL+ N++ E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSR
Sbjct: 1336 -PIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSR 1394
Query: 1839 VVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTN 2018
V+L +EG G DYINANYVDGY + +YIATQGPLPETF DFWRMVWE++S TIVM+T
Sbjct: 1395 VILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTR 1454
Query: 2019 LEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQY 2198
LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L G E RE++ Q+
Sbjct: 1455 LEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQF 1514
Query: 2199 TAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYD 2378
TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLER++ +
Sbjct: 1515 TAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPE 1574
Query: 2379 NTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-P 2555
TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA L+ ++ L+Q
Sbjct: 1575 KTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVE 1634
Query: 2556 SADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADG 2735
+ ++G+++EF+ L K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +G
Sbjct: 1635 PGEHVTGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEG 1694
Query: 2736 SDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSD 2915
SDYINAS+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ ML + E G+E+C
Sbjct: 1695 SDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQ 1754
Query: 2916 YWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHT 3095
YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G P +
Sbjct: 1755 YWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKS 1814
Query: 3096 ADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTV 3275
+ F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TV
Sbjct: 1815 GEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTV 1874
Query: 3276 KLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
K+LRT+R M+Q ++Y F D+++
Sbjct: 1875 KMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1909
Score = 38.9 bits (89), Expect = 0.85
Identities = 52/220 (23%), Positives = 86/220 (38%), Gaps = 11/220 (5%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARSE 525
Query: 357 NSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWTN 527
S+ L+W + PR ++ + +EL G++V + Y+ +
Sbjct: 526 TSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVED 570
Query: 528 LRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPP 641
L+P+ Y + R+ P G + P ++ + P+ PP
Sbjct: 571 LKPNTEYAFRLAARS-PQGLGAFTPVVRQRTLQSKPSAPP 609
>gi|1085568|pir||S46217 protein-tyrosine-phosphatase (EC 3.1.3.48)
type sigma precursor - rat
Length = 1863
Score = 703 bits (1815), Expect = 0.0
Identities = 430/1138 (37%), Positives = 615/1138 (53%), Gaps = 12/1138 (1%)
Frame = +3
Query: 3 LVGPPTNVRVEATSNSTAVVQW-DFESQKADSFVVKYMHE------PGNRMDTEKWKQLP 161
++GP NV S + +++W + + ++KY PG +TE
Sbjct: 866 ILGPAGNV-----SAGSVILRWLPPVPAEGNGAIIKYTVSVREAGTPGPATETE------ 914
Query: 162 VVSIDKENPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV 341
+ + + + + L Y V A GP S PP +N +V
Sbjct: 915 LAAAAQPGAETALTLQGLRPETAYELRVRAHTRRGPGPFS-PPLRYRLARDPVSPKNFKV 973
Query: 342 LWKTSNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLW 521
SV L+WE+ P N Y + T K N G DVD + + L
Sbjct: 974 KMIMKTSVLLSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLI 1017
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
T+L+PH Y + R G + +G P V PK D+ G+ ++
Sbjct: 1018 THLKPHTFYNFVLTNRGSSLGGLQQTVTARTAFNMLSGKPSV-APK-PDNDGS-----IV 1070
Query: 702 RLTPATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKL 881
P + + +Y+I++VP S PI L +L + LS +L
Sbjct: 1071 VYLPDGQSPVTVQNYFIVMVPLRKSRGGQF---PILLGSPEDMDLEELIQDLS-----RL 1122
Query: 882 KRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLY 1061
+R++ + +R+ VP Y+ AR S F G+ + Y
Sbjct: 1123 QRRSL---------------RHSRQLEVPRPYIAARFSI--------LPAVFHPGNQKQY 1159
Query: 1062 DGFTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSA 1241
GF N LE Y L + A + + T ++ S ++PF + +
Sbjct: 1160 GGFDNRGLEPGHRYVLFVLAVLQKNEPT-----------------FAASPFSDPFQLDNP 1202
Query: 1242 LRGA---SQKSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTX 1409
++ WV G +A + + IV ++ + + + K PR
Sbjct: 1203 DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR----------- 1251
Query: 1410 XXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYA 1589
T LL+ ++ + P HH + P R N
Sbjct: 1252 ------------TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQT 1279
Query: 1590 PVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWE 1769
P ++ P +P I ++A H+ERL+ N++ E+ESI+ GQ FTWE
Sbjct: 1280 PGMLSHPPIP---------------ITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWE 1324
Query: 1770 HSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLP 1949
HS+ + NK KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLP
Sbjct: 1325 HSNLEANKPKNRYANVIAYDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLP 1384
Query: 1950 ETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHY 2129
ETF DFWRMVWE++S T+VM+T LEE+SRVKCDQYWP+RGT TYG I+VTLL+++ LA +
Sbjct: 1385 ETFGDFWRMVWEQRSATVVMMTRLEEKSRVKCDQYWPNRGTETYGFIQVTLLDTMELATF 1444
Query: 2130 TMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHC 2309
+RT L G E RE++H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGP++ HC
Sbjct: 1445 CVRTFSLHKNGSSEKREVRHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPVVVHC 1504
Query: 2310 SAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAV 2489
SAG+GRTG FIVID MLER+R + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV
Sbjct: 1505 SAGVGRTGCFIVIDAMLERIRTEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAV 1564
Query: 2490 NSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
G+TEVPA L+ ++ L+Q + ++G+++EF+ L + K ++R A+LP N+ KN
Sbjct: 1565 GCGNTEVPARSLYTYIQKLAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKN 1624
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+++ +PY+S+RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+W
Sbjct: 1625 RLVNILPYESSRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALW 1684
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
E+NS I+ ML + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D
Sbjct: 1685 ENNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDAR 1744
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
+ RTVRQF F +WP+ G P + + F+DF+ QVH T QFG PI+VHC +G GRT V
Sbjct: 1745 DGQSRTVRQFQFTDWPEQGAPKSGEGFIDFIGQVHKTKEQFGQDAPISVHCSAGVGRTGV 1804
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1805 FITLSIVLERMRYEGVVDIFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1862
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|1407625|gb|AAC50567.1| PTPsigma
Length = 1911
Score = 703 bits (1815), Expect = 0.0
Identities = 416/1069 (38%), Positives = 581/1069 (53%), Gaps = 5/1069 (0%)
Frame = +3
Query: 189 KRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSVQ 368
+R + L Y V A GP S P + +N +V SV
Sbjct: 971 RRTLTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKNFKVKMIMKTSVL 1030
Query: 369 LTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMY 548
L+WE+ P N Y + T K N G DVD + + L T+L+PH Y
Sbjct: 1031 LSWEF--PDN---YNSPTPYKIQYN-----------GLTLDVDGRTTKKLITHLKPHTFY 1074
Query: 549 TIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEY 728
+ R G + T+T T ++ V G M+ L P +
Sbjct: 1075 NFVLTNRGSSLGGLQQ------TVTAWTAFNLLNGKPSVAPKPDADGFIMVYL-PDGQSP 1127
Query: 729 GPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEVGD 908
P+ Y+I++VP S + Q L L+ ++
Sbjct: 1128 VPVQSYFIVMVPLRKS------------------RGGQFLTPLGSPEDMDLEELIQDISR 1169
Query: 909 DSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYPLE 1088
+ + H +R+ VP Y+ AR S F GD + Y GF N LE
Sbjct: 1170 LQRRSLRH-----SRQLEVPRPYIAARFSV--------LPPTFHPGDQKQYGGFDNRGLE 1216
Query: 1089 HNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGA---SQ 1259
Y L + A + +K ++ S ++PF + + +
Sbjct: 1217 PGHRYVLFVLA-----------------VLQKSEPTFAASPFSDPFQLDNPDPQPIVDGE 1259
Query: 1260 KSSPWV-GACIAFLVLFSIVGMLICWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXX 1436
+ WV G +A + + IV ++ + + + K PR
Sbjct: 1260 EGLIWVIGPVLAVVFIICIVIAILLYKNKPDSKRKDSEPR-------------------- 1299
Query: 1437 XXETSKLLSTSNEYGRQIMNPYEQMNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSL 1616
T LL+ ++ + P HH + P R N P ++ P +
Sbjct: 1300 ---TKCLLNNAD------LAP-------HHPKD-------PVEMRRINFQTPGMLSHPPI 1336
Query: 1617 PNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKH 1796
PIA++A H ERL+ N++ E+ESI+ GQ FTWEHS+ ++NK
Sbjct: 1337 ---------------PIADMAEHTERLKANDSLKLSQEYESIDPGQQFTWEHSNLEVNKP 1381
Query: 1797 KNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRM 1976
KNRYANV AYDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFWRM
Sbjct: 1382 KNRYANVIAYDHSRVILQPIEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRM 1441
Query: 1977 VWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKM 2156
VWE++S TIVM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L
Sbjct: 1442 VWEQRSATIVMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTIELATFCVRTFSLHK 1501
Query: 2157 VGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGA 2336
G E RE++ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG
Sbjct: 1502 NGSSEKREVRQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGC 1561
Query: 2337 FIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPA 2516
FIVID MLER++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA
Sbjct: 1562 FIVIDAMLERIKPEKTVDVYGHVTLMRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPA 1621
Query: 2517 SRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYD 2693
L+ ++ L+Q + ++G+++EF+ L K ++R ANLP + KNR+++ +PY+
Sbjct: 1622 RSLYAYIQKLAQVEPGEHVTGMELEFKRLANSKAHTSRFISANLPCKKFKNRLVNIMPYE 1681
Query: 2694 SNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAM 2873
S RV ++ + G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ M
Sbjct: 1682 STRVCLQPIRGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVM 1741
Query: 2874 LVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQ 3053
L + E G+E+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQ
Sbjct: 1742 LTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQ 1801
Query: 3054 FHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILD 3233
F F +WP+ G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+
Sbjct: 1802 FQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLE 1861
Query: 3234 RMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
RMR E VVD+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1862 RMRYEGVVDIFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 1910
Score = 41.6 bits (96), Expect = 0.13
Identities = 53/221 (23%), Positives = 87/221 (38%), Gaps = 11/221 (4%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDK 179
PP NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PPRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQK 465
Query: 180 EN--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKT 353
N V L + Y VLA + GP SDP V NLR ++
Sbjct: 466 HNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEARS 525
Query: 354 SNSVQLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVD---EKHREYLWT 524
S+ L+W + PR ++ + +EL G++V + Y+
Sbjct: 526 ETSITLSW--SPPR----------QESIIKYEL---LFREGDHGREVGRTFDPTTSYVVE 570
Query: 525 NLRPHMMYTIHVGVRTLPPGARKYWP--QEVVTITDPTGPP 641
+L+P+ Y + R+ P G + P ++ + P+ PP
Sbjct: 571 DLKPNTEYAFRLAARS-PQGLGAFTPVVRQRTLQSKPSAPP 610
>gi|15027042|emb|CAC44759.1| receptor protein-tyrosine phosphatase
sigma [Danio rerio]
Length = 857
Score = 702 bits (1813), Expect = 0.0
Identities = 325/580 (56%), Positives = 433/580 (74%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
++HP +PI+ELA H E L+ N+N E+ESI+ GQ FTWEHS+ ++NK KNRYANV A
Sbjct: 277 MNHPPIPISELAEHTELLKANDNLKLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIA 336
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV+L+ +EG G DYIN+NY+DGY K +YIATQGPLPETF DFWRMVWE+++ T+
Sbjct: 337 YDHSRVILAPIEGITGSDYINSNYIDGYRKQNAYIATQGPLPETFGDFWRMVWEQRAATV 396
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEE+SR+KCDQYWPSRGT TYG I+VTLL+++ LA + +RT L G E RE+
Sbjct: 397 VMMTRLEEKSRIKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKNGSSEKREV 456
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
+ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPII+HCSAG+GRTG FIVID MLE
Sbjct: 457 RQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIIAHCSAGVGRTGCFIVIDAMLE 516
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHI 2543
R++++ TVDIYG VT +R+QR+YMVQTE+QY FIHDA+L+AV G+TEV A L ++
Sbjct: 517 RIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVAARSLFSYIQK 576
Query: 2544 LSQPSA-DQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
L+Q A + +SG+++EF+ L K ++R ANLP N+ KNR+++ +PY++ RV ++ +
Sbjct: 577 LAQVEAGEHVSGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYETTRVCLQPI 636
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDYIN+S+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ ML + E G+
Sbjct: 637 RGLEGSDYINSSFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGR 696
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+
Sbjct: 697 EKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQ 756
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD
Sbjct: 757 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 816
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 817 IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 856
>gi|7248661|gb|AAF43607.1| receptor protein tyrosine phosphatase
CRYP-alpha [Xenopus laevis]
Length = 615
Score = 701 bits (1810), Expect = 0.0
Identities = 326/580 (56%), Positives = 430/580 (73%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
++HP +PIA+LA H E L+ N+N E+ES++ GQ FTWEHS+ ++NK KNRYANV A
Sbjct: 35 LNHPPIPIADLAEHTEHLKANDNLKLSQEYESVDPGQQFTWEHSNLEVNKAKNRYANVIA 94
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV+L VEG G DYINANY+DGY K +YIATQG LPETF DFWRMVWE++S T+
Sbjct: 95 YDHSRVILLPVEGIIGSDYINANYIDGYRKQNAYIATQGALPETFGDFWRMVWEQRSATV 154
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEE+SRVKCDQYWPSRGT TYG I+VTLL+++ LA + +RT L G E RE+
Sbjct: 155 VMMTKLEEKSRVKCDQYWPSRGTETYGMIQVTLLDTIELATFCVRTFSLHKSGSSEKREV 214
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
+ Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLE
Sbjct: 215 RQFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 274
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHI 2543
R++++ TVDIYG VT +R+QR+YMVQTE+QY FIHDA+L+AV G+TEVPA L+ ++
Sbjct: 275 RIKHEKTVDIYGHVTLMRSQRNYMVQTEDQYSFIHDALLEAVACGNTEVPARNLYTYIQN 334
Query: 2544 LSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
L+Q + + G+++EF+ L K ++R ANLP N+ KNR+++ +PY++ RV ++ +
Sbjct: 335 LAQIDVGEHVIGMELEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYETTRVCLQPI 394
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWR +WE+NS I+ ML + E G+
Sbjct: 395 RGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGR 454
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+
Sbjct: 455 EKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQ 514
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD
Sbjct: 515 GVPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 574
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 575 IFQTVKMLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYA 614
>gi|1083485|pir||S50893 protein-tyrosine-phosphatase (EC 3.1.3.48),
receptor type sigma precursor - mouse
gi|587484|emb|CAA57732.1| protein-tyrosine-phosphatase [Mus musculus]
Length = 1907
Score = 701 bits (1810), Expect = 0.0
Identities = 323/580 (55%), Positives = 435/580 (74%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
+SHP +PI ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + NK KNRYANV A
Sbjct: 1327 LSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIA 1386
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFWRMVWE++S T+
Sbjct: 1387 YDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATV 1446
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L G RE+
Sbjct: 1447 VMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSGKREV 1506
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
+H Q+TAWPDHGVP++PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLE
Sbjct: 1507 RHFQFTAWPDHGVPEYPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1566
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHI 2543
R++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV+ G+TEVPA L+ ++
Sbjct: 1567 RIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVSCGNTEVPARSLYTYIQK 1626
Query: 2544 LSQ-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
L+Q + ++G+++EF+ L + K ++R A+LP N+ KNR+++ +PY+S+RV ++ +
Sbjct: 1627 LAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPI 1686
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+ ML + E G+
Sbjct: 1687 RGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGR 1746
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+
Sbjct: 1747 EKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQ 1806
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD
Sbjct: 1807 GAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1866
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1867 IFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1906
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|15292281|gb|AAK93409.1| LD45391p [Drosophila melanogaster]
Length = 1597
Score = 699 bits (1803), Expect = 0.0
Identities = 326/580 (56%), Positives = 425/580 (73%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
+SHP +PI+E ANHIERL+ N+N F E+ESIE GQ FTW++S+ + NK KNRYANV A
Sbjct: 1017 ISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTA 1076
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV L VEG G DYINANY DGY K +Y+ATQGPL ETF DFWRM WE ++ TI
Sbjct: 1077 YDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATI 1136
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEER+R+KCDQYWP+RGT TYG I VT+ E+ LA Y++RT +L G + REI
Sbjct: 1137 VMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREI 1196
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
K LQ+TAWPDHGVPDHP PFL FL+R + L P ++GP+I HCSAG+GRTG +IVID MLE
Sbjct: 1197 KQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLE 1256
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLH- 2540
R++++ +DIYG VT LRAQR+YMVQTE+QYIFIHDA+L+A+ G TEVPA LH HL
Sbjct: 1257 RMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQK 1316
Query: 2541 ILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
+L + +SG+++EF+ L+ +K S++ ANLP N+ KNR++ +PY+S+RV + +
Sbjct: 1317 LLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPI 1376
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDY+NAS+IDGY+ R AYIA Q P + A DFWR +WEHNS I+ ML + E G+
Sbjct: 1377 HGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGR 1436
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E V+ VV+P+AEY+M Y LREF+++D RTVRQF F++WP+
Sbjct: 1437 EKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQ 1496
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPITVHC +G GR+ VFI LSI+L+RM+ E V+D
Sbjct: 1497 GVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLD 1556
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
VF TV++LR++R M+Q +QYHF DN++
Sbjct: 1557 VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYT 1596
Score = 71.2 bits (173), Expect = 2e-10
Identities = 96/401 (23%), Positives = 156/401 (37%), Gaps = 9/401 (2%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPV---VSIDKEN 185
P +++ EATS TA + W+ + + K + D + W+ V S D N
Sbjct: 578 PMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVEDLDDWQTKTVGLTESADLVN 637
Query: 186 PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSV 365
++FA YA + A N G S+ TV + P + NLR +++S+
Sbjct: 638 LEKFA---------QYAVAIAARFKNGLGRLSEKVTV--RIKPEDVPLNLRAHDVSTHSM 686
Query: 366 QLTWEYNGPRN---VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKH--REYLWTNL 530
L+W + P V + ++ K +V+ + +T P +++ KH + + L
Sbjct: 687 TLSW--SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPK--REIILKHYVKTHTINEL 742
Query: 531 RPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLT 710
P Y ++V P Y P +T+T P V D G G++++ +
Sbjct: 743 SPFTTYNVNVSAI---PSDYSYRPPTKITVTTQMAAPQPMVKP--DFYGVVNGEEILVIL 797
Query: 711 P-ATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKR 887
P A+EEYGPISHY++++VP ED NL
Sbjct: 798 PQASEEYGPISHYYLVVVP-----EDKSNL------------------------------ 822
Query: 888 KASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDG 1067
++ D + P + R P Y+ A+ + F +G Y
Sbjct: 823 --HKIPDQFLTDDLLPGRNKPERPNAP--YIAAKFPQRSIP------FTFHLGSGDDYHN 872
Query: 1068 FTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLS 1190
FTN LE YR+ +RA D K + +P SE LS
Sbjct: 873 FTNRKLEREKRYRIFVRAVV--DTPQKHLYTS-SPFSEFLS 910
>gi|125977|sp|P16621|LAR_DROME Protein-tyrosine phosphatase Lar
precursor (Protein-tyrosine-phosphate phosphohydrolase)
(dLAR)
gi|538578|pir||TDFFLK protein-tyrosine-phosphatase (EC 3.1.3.48) DLAR
precursor - fruit fly (Drosophila melanogaster)
gi|157812|gb|AAA28668.1| protein tyrosine phosphatase (DLAR)
precursor
gi|1209648|gb|AAC47002.1| protein tyrosine phosphatase DLAR
Length = 2029
Score = 699 bits (1803), Expect = 0.0
Identities = 326/580 (56%), Positives = 425/580 (73%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
+SHP +PI+E ANHIERL+ N+N F E+ESIE GQ FTW++S+ + NK KNRYANV A
Sbjct: 1449 ISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTA 1508
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV L VEG G DYINANY DGY K +Y+ATQGPL ETF DFWRM WE ++ TI
Sbjct: 1509 YDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATI 1568
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEER+R+KCDQYWP+RGT TYG I VT+ E+ LA Y++RT +L G + REI
Sbjct: 1569 VMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREI 1628
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
K LQ+TAWPDHGVPDHP PFL FL+R + L P ++GP+I HCSAG+GRTG +IVID MLE
Sbjct: 1629 KQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLE 1688
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLH- 2540
R++++ +DIYG VT LRAQR+YMVQTE+QYIFIHDA+L+A+ G TEVPA LH HL
Sbjct: 1689 RMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQK 1748
Query: 2541 ILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
+L + +SG+++EF+ L+ +K S++ ANLP N+ KNR++ +PY+S+RV + +
Sbjct: 1749 LLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPI 1808
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDY+NAS+IDGY+ R AYIA Q P + A DFWR +WEHNS I+ ML + E G+
Sbjct: 1809 HGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGR 1868
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E V+ VV+P+AEY+M Y LREF+++D RTVRQF F++WP+
Sbjct: 1869 EKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQ 1928
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPITVHC +G GR+ VFI LSI+L+RM+ E V+D
Sbjct: 1929 GVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLD 1988
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
VF TV++LR++R M+Q +QYHF DN++
Sbjct: 1989 VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYT 2028
Score = 71.2 bits (173), Expect = 2e-10
Identities = 96/401 (23%), Positives = 156/401 (37%), Gaps = 9/401 (2%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPV---VSIDKEN 185
P +++ EATS TA + W+ + + K + D + W+ V S D N
Sbjct: 1010 PMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVEDLDDWQTKTVGLTESADLVN 1069
Query: 186 PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSV 365
++FA YA + A N G S+ TV + P + NLR +++S+
Sbjct: 1070 LEKFA---------QYAVAIAARFKNGLGRLSEKVTV--RIKPEDVPLNLRAHDVSTHSM 1118
Query: 366 QLTWEYNGPRN---VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKH--REYLWTNL 530
L+W + P V + ++ K +V+ + +T P +++ KH + + L
Sbjct: 1119 TLSW--SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPK--REIILKHYVKTHTINEL 1174
Query: 531 RPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLT 710
P Y ++V P Y P +T+T P V D G G++++ +
Sbjct: 1175 SPFTTYNVNVSAI---PSDYSYRPPTKITVTTQMAAPQPMVKP--DFYGVVNGEEILVIL 1229
Query: 711 P-ATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKR 887
P A+EEYGPISHY++++VP ED NL
Sbjct: 1230 PQASEEYGPISHYYLVVVP-----EDKSNL------------------------------ 1254
Query: 888 KASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDG 1067
++ D + P + R P Y+ A+ + F +G Y
Sbjct: 1255 --HKIPDQFLTDDLLPGRNKPERPNAP--YIAAKFPQRSIP------FTFHLGSGDDYHN 1304
Query: 1068 FTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLS 1190
FTN LE YR+ +RA D K + +P SE LS
Sbjct: 1305 FTNRKLEREKRYRIFVRAVV--DTPQKHLYTS-SPFSEFLS 1342
Score = 43.9 bits (102), Expect = 0.026
Identities = 45/188 (23%), Positives = 84/188 (43%), Gaps = 2/188 (1%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFES-QKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
PT+V++ + ++ ++W ++ + +V++Y + N+ +E + +
Sbjct: 325 PTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGIITM--------- 375
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMV-QNLRVLWKTSNSVQ 368
+ VV L+ + Y F V+AV N +GP S P T T +N++V +S+++
Sbjct: 376 -YYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMV 434
Query: 369 LTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMY 548
+TWE P V TG K Y + S Q VD + +++ PH +Y
Sbjct: 435 ITWE--PPETPNGQV--TGYKVYYTTNSNQPEASWN--SQMVDNSELTTV-SDVTPHAIY 487
Query: 549 TIHVGVRT 572
T+ V T
Sbjct: 488 TVRVQAYT 495
Score = 36.6 bits (83), Expect = 4.2
Identities = 79/370 (21%), Positives = 128/370 (34%), Gaps = 29/370 (7%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDF-ESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P NV+V S+ST V+ W+ E+ K + + W V +
Sbjct: 420 PRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMV------DNS 473
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV--LWKTSNSV 365
VSD+ H Y V A + GP S P V N R + +T+ ++
Sbjct: 474 ELTTVSDVTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTL 533
Query: 366 QLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMM 545
Q T + N+ Y + Y N ++ ++ + D L P +
Sbjct: 534 QWTKPTHSSENIVHYELY-WNDTYANQAHHKRISNSEAYTLD-----------GLYPDTL 581
Query: 546 YTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLT----P 713
Y I + R+ P V T G P ++ + SS T I L+ P
Sbjct: 582 YYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTT------ISLSWLPPP 635
Query: 714 ATEEYGPISHYWIILVPA----NYSTEDVVNLDPI---ELEKATAEKRAQLA-------- 848
G I +Y + V + +T +N+ I EL++ T K LA
Sbjct: 636 VERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGP 695
Query: 849 -------RSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRV 1007
R+ P KA+ + S S+ P ++ R + G ++ A+ D
Sbjct: 696 RSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEG 755
Query: 1008 KQQYRNNQPF 1037
K N+PF
Sbjct: 756 KGFL--NEPF 763
>gi|24585307|ref|NP_523604.2| CG10443-PA [Drosophila melanogaster]
gi|22946866|gb|AAF53837.3| CG10443-PA [Drosophila melanogaster]
Length = 2029
Score = 699 bits (1803), Expect = 0.0
Identities = 326/580 (56%), Positives = 425/580 (73%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
+SHP +PI+E ANHIERL+ N+N F E+ESIE GQ FTW++S+ + NK KNRYANV A
Sbjct: 1449 ISHPPIPISEFANHIERLKSNDNQKFSQEYESIEPGQQFTWDNSNLEHNKSKNRYANVTA 1508
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV L VEG G DYINANY DGY K +Y+ATQGPL ETF DFWRM WE ++ TI
Sbjct: 1509 YDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATI 1568
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEER+R+KCDQYWP+RGT TYG I VT+ E+ LA Y++RT +L G + REI
Sbjct: 1569 VMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFNDRREI 1628
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
K LQ+TAWPDHGVPDHP PFL FL+R + L P ++GP+I HCSAG+GRTG +IVID MLE
Sbjct: 1629 KQLQFTAWPDHGVPDHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLE 1688
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLH- 2540
R++++ +DIYG VT LRAQR+YMVQTE+QYIFIHDA+L+A+ G TEVPA LH HL
Sbjct: 1689 RMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAIICGVTEVPARNLHTHLQK 1748
Query: 2541 ILSQPSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
+L + +SG+++EF+ L+ +K S++ ANLP N+ KNR++ +PY+S+RV + +
Sbjct: 1749 LLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVHILPYESSRVYLTPI 1808
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDY+NAS+IDGY+ R AYIA Q P + A DFWR +WEHNS I+ ML + E G+
Sbjct: 1809 HGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVMLTKLKEMGR 1868
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E V+ VV+P+AEY+M Y LREF+++D RTVRQF F++WP+
Sbjct: 1869 EKCFQYWPHERSVRYQYYVVDPIAEYNMPQYKLREFKVTDARDGSSRTVRQFQFIDWPEQ 1928
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPITVHC +G GR+ VFI LSI+L+RM+ E V+D
Sbjct: 1929 GVPKSGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLSIVLERMQYEGVLD 1988
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
VF TV++LR++R M+Q +QYHF DN++
Sbjct: 1989 VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGSFDNYT 2028
Score = 71.2 bits (173), Expect = 2e-10
Identities = 96/401 (23%), Positives = 156/401 (37%), Gaps = 9/401 (2%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPV---VSIDKEN 185
P +++ EATS TA + W+ + + K + D + W+ V S D N
Sbjct: 1010 PMSLQAEATSEQTAEIWWEPVTSRGKLLGYKIFYTMTAVEDLDDWQTKTVGLTESADLVN 1069
Query: 186 PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNSV 365
++FA YA + A N G S+ TV + P + NLR +++S+
Sbjct: 1070 LEKFA---------QYAVAIAARFKNGLGRLSEKVTV--RIKPEDVPLNLRAHDVSTHSM 1118
Query: 366 QLTWEYNGPRN---VGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKH--REYLWTNL 530
L+W + P V + ++ K +V+ + +T P +++ KH + + L
Sbjct: 1119 TLSW--SPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPK--REIILKHYVKTHTINEL 1174
Query: 531 RPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLT 710
P Y ++V P Y P +T+T P V D G G++++ +
Sbjct: 1175 SPFTTYNVNVSAI---PSDYSYRPPTKITVTTQMAAPQPMVKP--DFYGVVNGEEILVIL 1229
Query: 711 P-ATEEYGPISHYWIILVPANYSTEDVVNLDPIELEKATAEKRAQLARSLSVSPSKKLKR 887
P A+EEYGPISHY++++VP ED NL
Sbjct: 1230 PQASEEYGPISHYYLVVVP-----EDKSNL------------------------------ 1254
Query: 888 KASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRVKQQYRNNQPFIVGDSQLYDG 1067
++ D + P + R P Y+ A+ + F +G Y
Sbjct: 1255 --HKIPDQFLTDDLLPGRNKPERPNAP--YIAAKFPQRSIP------FTFHLGSGDDYHN 1304
Query: 1068 FTNYPLEHNLHYRLMMRAFAKNDVRTKDSFEQRAPMSEKLS 1190
FTN LE YR+ +RA D K + +P SE LS
Sbjct: 1305 FTNRKLEREKRYRIFVRAVV--DTPQKHLYTS-SPFSEFLS 1342
Score = 44.7 bits (104), Expect = 0.015
Identities = 46/188 (24%), Positives = 83/188 (43%), Gaps = 2/188 (1%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFES-QKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
PT+V++ + ++ ++W ++ + +V++Y + N+ +E + +
Sbjct: 325 PTDVQISEVTATSVRLEWSYKGPEDLQYYVIQYKPKNANQAFSEISGIITM--------- 375
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMV-QNLRVLWKTSNSVQ 368
+ VV L+ + Y F V+AV N +GP S P T T +N++V +S+++
Sbjct: 376 -YYVVRALSPYTEYEFYVIAVNNIGRGPPSAPATCTTGETKMESAPRNVQVRTLSSSTMV 434
Query: 369 LTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMY 548
+TWE P V TG K Y + S Q VD + + L PH +Y
Sbjct: 435 ITWE--PPETPNGQV--TGYKVYYTTNSNQPEASWN--SQMVDNSELTTV-SELTPHAIY 487
Query: 549 TIHVGVRT 572
T+ V T
Sbjct: 488 TVRVQAYT 495
Score = 36.2 bits (82), Expect = 5.5
Identities = 79/370 (21%), Positives = 128/370 (34%), Gaps = 29/370 (7%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDF-ESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P NV+V S+ST V+ W+ E+ K + + W V +
Sbjct: 420 PRNVQVRTLSSSTMVITWEPPETPNGQVTGYKVYYTTNSNQPEASWNSQMV------DNS 473
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRV--LWKTSNSV 365
VS+L H Y V A + GP S P V N R + +T+ ++
Sbjct: 474 ELTTVSELTPHAIYTVRVQAYTSMGAGPMSTPVQVKAQQGVPSQPSNFRATDIGETAVTL 533
Query: 366 QLTWEYNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMM 545
Q T + N+ Y + Y N ++ ++ + D L P +
Sbjct: 534 QWTKPTHSSENIVHYELY-WNDTYANQAHHKRISNSEAYTLD-----------GLYPDTL 581
Query: 546 YTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLT----P 713
Y I + R+ P V T G P ++ + SS T I L+ P
Sbjct: 582 YYIWLAARSQRGEGATTPPIPVRTKQYVPGAPPRNITAIATSSTT------ISLSWLPPP 635
Query: 714 ATEEYGPISHYWIILVPA----NYSTEDVVNLDPI---ELEKATAEKRAQLA-------- 848
G I +Y + V + +T +N+ I EL++ T K LA
Sbjct: 636 VERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLDELKRWTEYKIWVLAGTSVGDGP 695
Query: 849 -------RSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVPGAYVTARLSADRV 1007
R+ P KA+ + S S+ P ++ R + G ++ A+ D
Sbjct: 696 RSHPIILRTQEDVPGDPQDVKATPLNSTSIHVSWKPPLEKDRNGIIRGYHIHAQELRDEG 755
Query: 1008 KQQYRNNQPF 1037
K N+PF
Sbjct: 756 KGFL--NEPF 763
>gi|693993|emb|CAA58537.1| leucocyte common antigen-related protein
[Rattus norvegicus]
Length = 620
Score = 696 bits (1797), Expect = 0.0
Identities = 330/609 (54%), Positives = 437/609 (71%), Gaps = 1/609 (0%)
Frame = +3
Query: 1557 PTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNNNAGFQSEFE 1736
P R N P A PS PN + HP +PI +LA++IERL+ N+ F E+E
Sbjct: 15 PVEMRRLNYQTPGSSA-PSCPNISSMR---DHPPIPITDLADNIERLKANDGLKFSQEYE 70
Query: 1737 SIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGYDKP 1916
SI+ GQ FTWE+S++++NK KNRYANV AYDHSRV+L++++G PG DYINANY+DGY K
Sbjct: 71 SIDPGQQFTWENSNSEVNKPKNRYANVIAYDHSRVLLTSIDGVPGSDYINANYIDGYRKQ 130
Query: 1917 RSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEV 2096
+YIATQGPLPET DFWRMVWE+++ T+VM+T LEE+SRVKCDQYWP+RGT TYG I+V
Sbjct: 131 NAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLEEKSRVKCDQYWPARGTETYGLIQV 190
Query: 2097 TLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLN 2276
TL+++V LA YTMRT L G E RE++ Q+ AWPDHGVP++PTP L FL+RVK N
Sbjct: 191 TLVDTVELATYTMRTFALHKSGSSEKRELRQFQFMAWPDHGVPEYPTPILAFLRRVKACN 250
Query: 2277 PNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQY 2456
P DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +R+QR+YMVQTE+QY
Sbjct: 251 PLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKTVDIYGHVTCMRSQRNYMVQTEDQY 310
Query: 2457 IFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSNRCT 2633
+FIH+A+L+A G TEV A L+ H+ L Q P + ++ +++EF+ L K ++R
Sbjct: 311 VFIHEALLEAAMCGHTEVLARNLYAHIQKLGQVPPGESVTAMELEFKLLANSKAHTSRFI 370
Query: 2634 VANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTN 2813
ANLP N+ KNR+++ +PY+ RV ++ + G +GSDYINAS++DGY+++ AYIATQ P
Sbjct: 371 SANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSDYINASFLDGYRQQKAYIATQGPLA 430
Query: 2814 ETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHY 2993
E+ DFWR +WEHNS II ML + E G+E+C YWP E + VV+PMAEY+M Y
Sbjct: 431 ESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQY 490
Query: 2994 HLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITV 3173
LREF+++D + RT+RQF F +WP+ G P T + F+DF+ QVH T QFG GPITV
Sbjct: 491 ILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGEGFIDFIGQVHKTKEQFGQDGPITV 550
Query: 3174 HCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXX 3353
HC +G GRT VFI LSI+L+RMR E VVD+F TVK LRT+R M+Q +QY
Sbjct: 551 HCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKTLRTQRPAMVQTEDQYQLCYRAALE 610
Query: 3354 XXXXXDNFS 3380
D+++
Sbjct: 611 YLGSFDHYA 619
>gi|18860896|ref|NP_569707.1| protein tyrosine phosphatase, receptor
type, F isoform 2 precursor; protein tyrosine
phosphatase, receptor type, F polypeptide;
receptor-linked protein-tyrosine phosphatase LAR;
leukocyte antigen-related tyrosine phosphatase;
LCA-homolog; leukocyte antigen-related (LAR) PTP receptor
[Homo sapiens]
Length = 1888
Score = 695 bits (1794), Expect = 0.0
Identities = 321/578 (55%), Positives = 427/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYD
Sbjct: 1310 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYD 1369
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1370 HSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 1429
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT T G I+VTLL++V LA YT+RT L G E RE++
Sbjct: 1430 MTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1489
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1490 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1549
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEVPA L+ H+ L
Sbjct: 1550 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG 1609
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L + K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1610 QVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1669
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1670 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1729
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1730 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1789
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1790 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1849
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1850 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1887
>gi|4506311|ref|NP_002831.1| protein tyrosine phosphatase, receptor
type, F isoform 1 precursor; protein tyrosine
phosphatase, receptor type, F polypeptide;
receptor-linked protein-tyrosine phosphatase LAR;
leukocyte antigen-related tyrosine phosphatase;
LCA-homolog; leukocyte antigen-related (LAR) PTP receptor
[Homo sapiens]
gi|125978|sp|P10586|PTPF_HUMAN LAR protein precursor (Leukocyte
antigen related)
gi|70146|pir||TDHULK leukocyte antigen-related protein precursor -
human
gi|34267|emb|CAA68754.1| put. LAR preprotein (AA -16 to 1881) [Homo
sapiens]
Length = 1897
Score = 695 bits (1794), Expect = 0.0
Identities = 321/578 (55%), Positives = 427/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYD
Sbjct: 1319 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYD 1378
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1379 HSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 1438
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT T G I+VTLL++V LA YT+RT L G E RE++
Sbjct: 1439 MTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1498
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1499 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1558
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEVPA L+ H+ L
Sbjct: 1559 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG 1618
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L + K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1619 QVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1678
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1679 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1738
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1739 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1798
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1799 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1858
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1859 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1896
>gi|34870151|ref|XP_346749.1| hypothetical protein XP_346748 [Rattus
norvegicus]
Length = 1898
Score = 694 bits (1791), Expect = 0.0
Identities = 321/578 (55%), Positives = 427/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYANV AYD
Sbjct: 1320 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYD 1379
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1380 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 1439
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 1440 MTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 1499
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1500 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1559
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 1560 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 1619
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1620 QVPPGESVTAMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1679
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1680 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1739
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1740 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1799
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1800 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1859
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1860 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1897
>gi|205131|gb|AAA41510.1| leukocyte common antigen related protein
Length = 864
Score = 694 bits (1791), Expect = 0.0
Identities = 321/578 (55%), Positives = 427/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYANV AYD
Sbjct: 286 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYD 345
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 346 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 405
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 406 MTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 465
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 466 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 525
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 526 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 585
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 586 QVPPGESVTAMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 645
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 646 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 705
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 706 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 765
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 766 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 825
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 826 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 863
>gi|249840|gb|AAB22251.1| LAR, leukocyte common antigen-related
protein=transmembrane receptor phosphotyrosine
phosphatase [rats, fibroblast 208F cells, Peptide, 1887
aa]
Length = 1887
Score = 694 bits (1791), Expect = 0.0
Identities = 321/578 (55%), Positives = 427/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYANV AYD
Sbjct: 1309 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYD 1368
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1369 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 1428
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 1429 MTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 1488
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1489 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1548
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 1549 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 1608
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1609 QVPPGESVTAMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1668
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1669 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1728
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1729 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1788
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1789 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1848
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1849 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1886
>gi|31873230|emb|CAD97607.1| hypothetical protein [Homo sapiens]
Length = 1191
Score = 694 bits (1790), Expect = 0.0
Identities = 320/578 (55%), Positives = 427/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYD
Sbjct: 613 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYD 672
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 673 HSRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 732
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT T G I+VTLL++V LA YT+RT L G E RE++
Sbjct: 733 MTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 792
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 793 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 852
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEVPA L+ H+ L
Sbjct: 853 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG 912
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L + K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 913 QVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 972
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 973 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1032
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1033 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1092
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1093 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1152
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R ++Q +QY D+++
Sbjct: 1153 QTVKTLRTQRPAIVQTEDQYQLCYRAALEYLGSFDHYA 1190
>gi|28981412|gb|AAH48768.1| PTPRF protein [Homo sapiens]
Length = 1898
Score = 693 bits (1789), Expect = 0.0
Identities = 320/578 (55%), Positives = 426/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYD
Sbjct: 1320 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYD 1379
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +Y ATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1380 HSRVILTSIDGVPGSDYINANYIDGYRKQNAYTATQGPLPETMGDFWRMVWEQRTATVVM 1439
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT T G I+VTLL++V LA YT+RT L G E RE++
Sbjct: 1440 MTRLEEKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQ 1499
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1500 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1559
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEVPA L+ H+ L
Sbjct: 1560 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLG 1619
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L + K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1620 QVPPGESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1679
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1680 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1739
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1740 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1799
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1800 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1859
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1860 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1897
>gi|34980829|gb|AAH57166.1| Ptprf protein [Mus musculus]
Length = 1529
Score = 693 bits (1789), Expect = 0.0
Identities = 321/578 (55%), Positives = 426/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYANV AYD
Sbjct: 951 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYD 1010
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1011 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 1070
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 1071 MTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 1130
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1131 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1190
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 1191 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 1250
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1251 QVPPGESVTAMELEFKLLANSKAHTSRFVSANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1310
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1311 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1370
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1371 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1430
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1431 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1490
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1491 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1528
Score = 36.6 bits (83), Expect = 4.2
Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 5/193 (2%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENP 188
G PT + V T+ TA++QW + + G R+ + + +ID
Sbjct: 444 GRPT-MMVSTTAMHTALLQWHPPKELPGELL-------GYRLQYRRADEARPNTIDFGKD 495
Query: 189 KRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSD---PPTVLESVTPTYMVQNLRVLWKTSN 359
+ V+ L+ Y F + A NR GP + T E V P+ QNLRV T++
Sbjct: 496 DQHFTVTGLHKGATYVFRLAA--KNRAGPGEEFEKEITTPEDV-PSGFPQNLRVTGLTTS 552
Query: 360 SVQLTWE--YNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLR 533
+ +LTW+ RN G N+T +N +L+ + ++ ++ H L L+
Sbjct: 553 TTELTWDPPVLAERN-GHITNYTVVYRDINSQLELQNVT--------NDTHLTLL--GLK 601
Query: 534 PHMMYTIHVGVRT 572
P Y I V T
Sbjct: 602 PDTTYDIKVRAHT 614
>gi|25092609|ref|NP_035348.1| protein tyrosine phosphatase, receptor
type, S [Mus musculus]
gi|464191|dbj|BAA05886.1| protein tyrosine phosphatase PTPT9 [Mus
musculus]
gi|1093331|prf||2103274A receptor type protein Tyr phosphatase
Length = 1904
Score = 693 bits (1789), Expect = 0.0
Identities = 322/580 (55%), Positives = 432/580 (73%), Gaps = 1/580 (0%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
+SHP +PI ++A H+ERL+ N++ E+ESI+ GQ FTWEHS+ + NK KNRYANV A
Sbjct: 1327 LSHPPIPITDMAEHMERLKANDSLKLSQEYESIDPGQQFTWEHSNLEANKPKNRYANVIA 1386
Query: 1824 YDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTI 2003
YDHSRV+L +EG G DYINANYVDGY + +YIATQGPLPETF DFWRMVWE++S T+
Sbjct: 1387 YDHSRVILQPLEGIMGSDYINANYVDGYRRQNAYIATQGPLPETFGDFWRMVWEQRSATV 1446
Query: 2004 VMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREI 2183
VM+T LEE+SR+KCDQYWP+RGT TYG I+VTLL+++ LA + +RT L G E RE+
Sbjct: 1447 VMMTRLEEKSRIKCDQYWPNRGTETYGFIQVTLLDTMELATFCVRTFSLHKNGSSEKREV 1506
Query: 2184 KHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLE 2363
+H Q+TAWPDHG +PTPFL FL+RVKT NP DAGPI+ HCSAG+GRTG FIVID MLE
Sbjct: 1507 RHFQFTAWPDHG---YPTPFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLE 1563
Query: 2364 RLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHI 2543
R++ + TVD+YG VT +R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA L+ ++
Sbjct: 1564 RIKTEKTVDVYGHVTLMRSQRNYMVQTEDQYGFIHEALLEAVGCGNTEVPARSLYTYIQK 1623
Query: 2544 LSQPS-ADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLL 2720
L+Q + ++G+++EF+ L + K ++R A+LP N+ KNR+++ +PY+S+RV ++ +
Sbjct: 1624 LAQVEPGEHVTGMELEFKRLASSKAHTSRFITASLPCNKFKNRLVNILPYESSRVCLQPI 1683
Query: 2721 PGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQ 2900
G +GSDYINAS+IDGY+++ AYIATQ P ET DFWRA+WE+NS I+ ML + E G+
Sbjct: 1684 RGVEGSDYINASFIDGYRQQKAYIATQGPLAETTEDFWRALWENNSTIVVMLTKLREMGR 1743
Query: 2901 EQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDV 3080
E+C YWP E + VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+
Sbjct: 1744 EKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQ 1803
Query: 3081 GKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVD 3260
G P + + F+DF+ QVH T QFG GPI+VHC +G GRT VFI LSI+L+RMR E VVD
Sbjct: 1804 GAPKSGEGFIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVD 1863
Query: 3261 VFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
+F TVK+LRT+R M+Q ++Y F D+++
Sbjct: 1864 IFQTVKVLRTQRPAMVQTEDEYQFCFQAALEYLGSFDHYA 1903
Score = 37.4 bits (85), Expect = 2.5
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 6/127 (4%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKADSFV----VKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P NV+ S +T +VQW+ E + + + V Y EP + PV + K
Sbjct: 417 PRNVQARMLSATTMIVQWE-EPVEPNGLIRGYRVYYTMEPEH----------PVGNWQKH 465
Query: 183 N--PKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTS 356
N V L + Y VLA + GP SDP V NLR K+
Sbjct: 466 NVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAEAKSE 525
Query: 357 NSVQLTW 377
S+ L+W
Sbjct: 526 TSIGLSW 532
>gi|1363186|pir||A57068 protein-tyrosine-phosphatase (EC 3.1.3.48),
receptor type f - mouse (fragment)
gi|993006|emb|CAA86070.1| protein tyrosine phosphatase [Mus musculus]
Length = 582
Score = 693 bits (1789), Expect = 0.0
Identities = 321/578 (55%), Positives = 426/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYANV AYD
Sbjct: 4 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYD 63
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 64 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 123
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 124 MTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 183
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 184 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 243
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 244 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 303
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 304 QVPPGESVTAMELEFKLLANSKAHTSRFVSANLPCNKFKNRLVNIMPYELTRVCLQPIRG 363
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 364 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 423
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 424 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 483
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 484 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 543
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 544 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 581
>gi|9507013|ref|NP_062122.1| protein tyrosine phosphatase, receptor
type, F; protein tyrosine phosphatase, receptor-type, F;
leukocyte antigen-related (LAR) PTP receptor; protein
tyrosine phosphatase receptor-type F [Rattus norvegicus]
gi|1071964|pir||S46216 leukocyte antigen-related protein precursor -
rat
gi|205133|gb|AAC37655.1| leukocyte common antigen-related phosphatase
Length = 1898
Score = 692 bits (1787), Expect = 0.0
Identities = 321/578 (55%), Positives = 426/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYANV AYD
Sbjct: 1320 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYANVIAYD 1379
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE++ T+VM
Sbjct: 1380 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRIATVVM 1439
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP+RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 1440 MTRLEEKSRVKCDQYWPARGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 1499
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1500 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1559
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 1560 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 1619
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1620 QVPPGESVTAMELEFKLLAGSKARASRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1679
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1680 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1739
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1740 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1799
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1800 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1859
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1860 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1897
>gi|7248659|gb|AAF43606.1| receptor protein tyrosine phosphatase LAR
[Xenopus laevis]
Length = 1788
Score = 691 bits (1784), Expect = 0.0
Identities = 322/578 (55%), Positives = 428/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI++LA++IERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYD
Sbjct: 1210 HPPIPISDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYD 1269
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++V+ PG DYINANY+DGY K +YIATQGPLPET +DFWRM+WE+++ TIVM
Sbjct: 1270 HSRVILTSVDAVPGSDYINANYIDGYRKQNAYIATQGPLPETITDFWRMMWEQRTATIVM 1329
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWPSRG+ TYG I+VTL+++V LA YT+RT + G E R+++
Sbjct: 1330 MTRLEEKSRVKCDQYWPSRGSETYGMIQVTLMDTVELATYTVRTFTVYKNGSNEKRDVRQ 1389
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP+ HCSAG+GRTG FIVID MLER+
Sbjct: 1390 FQFMAWPDHGVPEYPTPILGFLRRVKACNPPDAGPMFVHCSAGVGRTGCFIVIDAMLERV 1449
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+ + TVDIYG VT +R+QR+YMVQTE+QYIFIH+A+L+AV G TEVPA L+ H+ LS
Sbjct: 1450 KLEKTVDIYGHVTCMRSQRNYMVQTEDQYIFIHEALLEAVMCGVTEVPARSLYAHIQKLS 1509
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ +RV ++ + G
Sbjct: 1510 QVPPGESVTSMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELSRVSLQPIRG 1569
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS+IDGY+++ YIATQ P ET DFWR +WEHNS I+ ML + E G+E+
Sbjct: 1570 VEGSDYINASFIDGYRQQKGYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREK 1629
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1630 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1689
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1690 PKTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1749
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1750 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1787
>gi|18702313|ref|NP_035343.1| protein tyrosine phosphatase, receptor
type, F; leukocyte antigen-related (LAR) PTP receptor
[Mus musculus]
gi|11761808|gb|AAG40194.1| tyrosine phosphatase LAR [Mus musculus]
Length = 1898
Score = 689 bits (1777), Expect = 0.0
Identities = 319/578 (55%), Positives = 425/578 (73%), Gaps = 1/578 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP +PI +LA++IERL+ N+ F E+ESI+ GQ FTWE+S++++NK KNRYA+V AYD
Sbjct: 1320 HPPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNSEVNKPKNRYADVIAYD 1379
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM
Sbjct: 1380 HSRVLLTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVM 1439
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKCDQYWP RGT TYG I+VTL+++V LA YTMRT L G E RE++
Sbjct: 1440 MTRLEEKSRVKCDQYWPVRGTETYGLIQVTLVDTVELATYTMRTFALHKSGSSEKRELRQ 1499
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q+ AWPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1500 FQFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERM 1559
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ TVDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEV A L+ H+ L
Sbjct: 1560 KHEKTVDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAAMCGHTEVLARNLYAHIQKLG 1619
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
Q P + ++ +++EF+ L K ++R ANLP N+ KNR+++ +PY+ RV ++ + G
Sbjct: 1620 QVPPGESVTAMELEFKLLANSKAHTSRFVSANLPCNKFKNRLVNIMPYELTRVCLQPIRG 1679
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+
Sbjct: 1680 VEGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREK 1739
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1740 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1799
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P T + F+D + QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F
Sbjct: 1800 PKTGEGFIDXIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMF 1859
Query: 3267 TTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
TVK LRT+R M+Q +QY D+++
Sbjct: 1860 QTVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 1897
Score = 36.6 bits (83), Expect = 4.2
Identities = 50/193 (25%), Positives = 81/193 (41%), Gaps = 5/193 (2%)
Frame = +3
Query: 9 GPPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENP 188
G PT + V T+ TA++QW + + G R+ + + +ID
Sbjct: 813 GRPT-MMVSTTAMHTALLQWHPPKELPGELL-------GYRLQYRRADEARPNTIDFGKD 864
Query: 189 KRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSD---PPTVLESVTPTYMVQNLRVLWKTSN 359
+ V+ L+ Y F + A NR GP + T E V P+ QNLRV T++
Sbjct: 865 DQHFTVTGLHKGATYVFRLAA--KNRAGPGEEFEKEITTPEDV-PSGFPQNLRVTGLTTS 921
Query: 360 SVQLTWE--YNGPRNVGFYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLR 533
+ +LTW+ RN G N+T +N +L+ + ++ ++ H L L+
Sbjct: 922 TTELTWDPPVLAERN-GXITNYTVVYRDINSQLELQNVT--------NDTHLTLL--GLK 970
Query: 534 PHMMYTIHVGVRT 572
P Y I V T
Sbjct: 971 PDTTYDIKVRAHT 983
>gi|7766938|pdb|1LAR|A Chain A, Crystal Structure Of The Tandem
Phosphatase Domains Of Rptp Lar
gi|7766939|pdb|1LAR|B Chain B, Crystal Structure Of The Tandem
Phosphatase Domains Of Rptp Lar
Length = 575
Score = 686 bits (1770), Expect = 0.0
Identities = 318/573 (55%), Positives = 423/573 (73%), Gaps = 1/573 (0%)
Frame = +3
Query: 1665 IAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVV 1844
I +LA++IERL+ N+ F E+ESI+ GQ FTWE+S+ ++NK KNRYANV AYDHSRV+
Sbjct: 2 ITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDHSRVI 61
Query: 1845 LSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLE 2024
L++++G PG DYINANY+DGY K +YIATQGPLPET DFWRMVWE+++ T+VM+T LE
Sbjct: 62 LTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMMTRLE 121
Query: 2025 ERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTA 2204
E+SRVKCDQYWP+RGT T G I+VTLL++V LA YT+RT L G E RE++ Q+ A
Sbjct: 122 EKSRVKCDQYWPARGTETCGLIQVTLLDTVELATYTVRTFALHKSGSSEKRELRQFQFMA 181
Query: 2205 WPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNT 2384
WPDHGVP++PTP L FL+RVK NP DAGP++ HCSAG+GRTG FIVID MLER++++ T
Sbjct: 182 WPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMKHEKT 241
Query: 2385 VDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSA 2561
VDIYG VT +R+QR+YMVQTE+QY+FIH+A+L+A G TEVPA L+ H+ L Q P
Sbjct: 242 VDIYGHVTCMRSQRNYMVQTEDQYVFIHEALLEAATCGHTEVPARNLYAHIQKLGQVPPG 301
Query: 2562 DQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSD 2741
+ ++ +++EF+ L + K ++R ANLP N+ KNR+++ +PY+ RV ++ + G +GSD
Sbjct: 302 ESVTAMELEFKLLASSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGVEGSD 361
Query: 2742 YINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYW 2921
YINAS++DGY+++ AYIATQ P E+ DFWR +WEHNS II ML + E G+E+C YW
Sbjct: 362 YINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTKLREMGREKCHQYW 421
Query: 2922 PLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTAD 3101
P E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G P T +
Sbjct: 422 PAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKTGE 481
Query: 3102 HFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKL 3281
F+DF+ QVH T QFG GPITVHC +G GRT VFI LSI+L+RMR E VVD+F TVK
Sbjct: 482 GFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQTVKT 541
Query: 3282 LRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
LRT+R M+Q +QY D+++
Sbjct: 542 LRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYA 574
>gi|47228368|emb|CAG07763.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 1790
Score = 685 bits (1767), Expect = 0.0
Identities = 400/1044 (38%), Positives = 556/1044 (52%), Gaps = 3/1044 (0%)
Frame = +3
Query: 258 NNRQGPCSDPPTVLESVTP--TYMVQNLRVLWKTSNSVQLTWEY-NGPRNVGFYVNHTGR 428
+N+ GP P VL T + +N V T SV LTWE+ G F V + +
Sbjct: 884 HNKAGPGPFSPPVLSRTLALETDVPRNFSVNLATKTSVLLTWEFPEGSNPYRFTVEYNRQ 943
Query: 429 KDYVNHELQEKTMSTPGFGQDVDEKHREYLWTNLRPHMMYTIHVGVRTLPPGARKYWPQE 608
K +VD + ++ + NL+P Y + T P G
Sbjct: 944 K------------------MEVDARLKKAVIPNLQPDTSYDFKI---TAPEGNMGGLRHR 982
Query: 609 VVTITDPTGPPFVDVPKLVDSSGTQPGQQMIRLTPATEEYGPISHYWIILVPANYSTEDV 788
+ T P P + P++ + T+ +I P+ E PI + ++++VP
Sbjct: 983 ISAKTSP--PITIRRPEIDHTRDTETTVTII--LPSLETRTPIKNVYVVVVPL------- 1031
Query: 789 VNLDPIELEKATAEKRAQLARSLSVSPSKKLKRKASEVGDDSQSASYHPKEKRARRATVP 968
+RA+ SP + + + Q + K+ RRA +
Sbjct: 1032 --------------RRARGVLRHEKSPDEMDLEELLKDISQKQRDTRQQKQVDLRRAYIT 1077
Query: 969 GAYVTARLSADRVKQQYRNNQPFIVGDSQLYDGFTNYPLEHNLHYRLMMRAFAKNDVRTK 1148
+ A L A F +GD Y GF N L+ Y +
Sbjct: 1078 ARFTPATLPAF-----------FSLGDQLDYGGFENRALDAGQEYMFFIL---------- 1116
Query: 1149 DSFEQRAPMSEKLSRMYSDSVLTEPFTIKSALRGASQKSSPWVGACIAFLVLFSIVGMLI 1328
A ++ +MY S T+P + + L + I+ ++I
Sbjct: 1117 ------AELNSTTGKMYVASPYTDPVIAPDSDPQPLDAGDGLIWVVGPVLAVVFIICIVI 1170
Query: 1329 CWWLRCNKKSAGRHPRHGSITKVALTXXXXXXXXXXXXETSKLLSTSNEYGRQIMNPYEQ 1508
L NK+ +E G + + +
Sbjct: 1171 AILLYKNKRK------------------------------------DSEPGTKSLLSNAE 1194
Query: 1509 MNGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHI 1688
M +H + P R N P VA +SHP +PI ELA HI
Sbjct: 1195 MMAHHPTD--------PVEMRRINFQTPAIVAEAI-------RGMMSHPPIPINELAEHI 1239
Query: 1689 ERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYP 1868
E L+ N+N E+ESI+ Q FTWEHS+ ++NK KNRYANV AYDH+RV+L+ ++G
Sbjct: 1240 ELLKANDNLRLSQEYESIDPSQQFTWEHSNLEVNKPKNRYANVIAYDHTRVILAPIDGIL 1299
Query: 1869 GMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCD 2048
G DYINANY+DGY K +YIATQGPL ETF DFWRMVWE+++ ++VM+T LEE+SRVKCD
Sbjct: 1300 GNDYINANYIDGYRKQNAYIATQGPLAETFGDFWRMVWEQRTASVVMMTRLEEKSRVKCD 1359
Query: 2049 QYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPD 2228
QYWP+RGT TYG ++VTLL+++ LA + +RT L G E RE++ Q+TAWPDHGVP+
Sbjct: 1360 QYWPNRGTETYGMVQVTLLDTMELATFCVRTFSLHKSGSSERREVRQFQFTAWPDHGVPE 1419
Query: 2229 HPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVT 2408
+PTPFL FL+RVK NP DAGPI HCSAG+GRTG FIVID MLER+R++ TVDIYG VT
Sbjct: 1420 YPTPFLNFLRRVKACNPPDAGPITVHCSAGVGRTGCFIVIDAMLERIRHERTVDIYGHVT 1479
Query: 2409 ALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQPSADQLSGIDME 2588
+R+QR+YMVQTE+QY FIH+A+L+AV G+TEVPA L+ ++ LS
Sbjct: 1480 LMRSQRNYMVQTEDQYSFIHEALLEAVACGNTEVPARSLYSYMQKLS------------- 1526
Query: 2589 FRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDG 2768
+ L K ++R ANLP N+ KNR+++ +PY++ RV ++ + G +GSDYINAS+IDG
Sbjct: 1527 -KRLANTKAHTSRFVTANLPCNKFKNRLVNIMPYETTRVCLQPIRGLEGSDYINASYIDG 1585
Query: 2769 YKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVG 2948
Y+++ YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E +
Sbjct: 1586 YRQQRGYIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQ 1645
Query: 2949 MLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQV 3128
VV+PMAEY+M Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QV
Sbjct: 1646 YFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQV 1705
Query: 3129 HNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMI 3308
H T QFG GPI VHC +G GRT VFI LSI+L+RMR E VD+F TVK+LRT+R M+
Sbjct: 1706 HKTKEQFGQDGPIAVHCSAGVGRTGVFITLSIVLERMRYEGAVDIFQTVKMLRTQRPAMV 1765
Query: 3309 QEPEQYHFXXXXXXXXXXXXDNFS 3380
Q ++Y F D+++
Sbjct: 1766 QTEDEYQFCYQAALEYLGSFDHYA 1789
Score = 40.4 bits (93), Expect = 0.29
Identities = 32/126 (25%), Positives = 51/126 (40%), Gaps = 3/126 (2%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQ---KADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
PP NV+ S +T +V+W+ + + + V Y +P M+ +W+ I
Sbjct: 238 PPRNVQAHIISQNTVMVRWEEPEEPNGQVKGYRVYYTMDPSRPMN--EWQ------IHNV 289
Query: 183 NPKRFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSNS 362
+ +L + Y VLA + GP SDP V +V T S
Sbjct: 290 QDSVITTIQNLVTSETYTIQVLAFTSVGDGPFSDPVHVKVMPGVPGQPGKFKVGRVTDTS 349
Query: 363 VQLTWE 380
++LTWE
Sbjct: 350 IELTWE 355
>gi|47211684|emb|CAF92848.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2057
Score = 682 bits (1761), Expect = 0.0
Identities = 322/555 (58%), Positives = 416/555 (74%), Gaps = 1/555 (0%)
Frame = +3
Query: 1650 HPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYD 1829
HP + + +LA+ I+RL+ N N F EFESI+ GQ FTWEHS+ ++NK KNRYANV AYD
Sbjct: 1458 HPPIAVCDLADDIDRLKANENLRFSQEFESIDPGQQFTWEHSNLEINKPKNRYANVIAYD 1517
Query: 1830 HSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVM 2009
HSRV+L+ V+G PG DYINANYVDGY K +YIATQGPLPET SDFWRMVWE+++ TI+M
Sbjct: 1518 HSRVILAAVDGIPGSDYINANYVDGYRKQNAYIATQGPLPETLSDFWRMVWEQRTCTIIM 1577
Query: 2010 LTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKH 2189
+T LEE+SRVKC+QYWP+RGT TYG I+VTLL++V LA YT+RT L G E RE++
Sbjct: 1578 MTRLEEKSRVKCEQYWPARGTHTYGMIQVTLLDTVELATYTIRTFALYKNGSSEKREVRQ 1637
Query: 2190 LQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERL 2369
Q AWPDHGVP+ PTP L FL+RVK +P D+GP++ HCSAG+GRTG FIVID MLER+
Sbjct: 1638 FQLMAWPDHGVPECPTPILAFLRRVKACHPPDSGPMVVHCSAGVGRTGCFIVIDAMLERM 1697
Query: 2370 RYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILS 2549
+++ +VDIYG VT +RAQR+YMVQTEEQYIFIH+A+ +A G+TEVPA L+ H+ LS
Sbjct: 1698 KHEKSVDIYGHVTCMRAQRNYMVQTEEQYIFIHEALSEAAACGNTEVPARSLYGHIQKLS 1757
Query: 2550 Q-PSADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPG 2726
P + + I++EF+ L K ++R ANLP N+ KNR+++ +P++SNRV ++ + G
Sbjct: 1758 LIPPGETATTIELEFKKLAGSKAHTSRFISANLPCNKFKNRLVNILPFESNRVSLQPIRG 1817
Query: 2727 ADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQ 2906
+GSDYINAS+IDGY+++ AYIA+Q P ET DFWR +WEHNS II ML + E G+E+
Sbjct: 1818 VEGSDYINASFIDGYRQQKAYIASQGPLAETTEDFWRMLWEHNSTIIVMLTKLREMGREK 1877
Query: 2907 CSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGK 3086
C YWP E + VV+PMAEY+M Y LREF+++D + RT+RQF F +WP+ G
Sbjct: 1878 CHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGV 1937
Query: 3087 PHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVF 3266
P + + F+DF+ QVH T QFG GPI VHC +G GRT VFIALSI L+RMR E VVD+F
Sbjct: 1938 PKSGEGFIDFIGQVHKTKEQFGQDGPIAVHCSAGVGRTGVFIALSIALERMRFEGVVDLF 1997
Query: 3267 TTVKLLRTERQNMIQ 3311
TVK LRT+R M+Q
Sbjct: 1998 QTVKTLRTQRPAMVQ 2012
Score = 207 bits (528), Expect = 1e-51
Identities = 108/271 (39%), Positives = 153/271 (55%), Gaps = 8/271 (2%)
Frame = +3
Query: 1659 VPIAELANHIERLRM----NNNAGFQSEFESIETGQHFTWEHSSADM--NKHKNRYANVA 1820
VP L HI++L + + EF+ + + T SA++ NK KNR N+
Sbjct: 1744 VPARSLYGHIQKLSLIPPGETATTIELEFKKLAGSKAHTSRFISANLPCNKFKNRLVNIL 1803
Query: 1821 AYDHSRVVLSNVEGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVT 2000
++ +RV L + G G DYINA+++DGY + ++YIA+QGPL ET DFWRM+WE S
Sbjct: 1804 PFESNRVSLQPIRGVEGSDYINASFIDGYRQQKAYIASQGPLAETTEDFWRMLWEHNSTI 1863
Query: 2001 IVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVRE 2180
IVMLT L E R KC QYWP+ +A Y V + ++ Y +R ++ + + R
Sbjct: 1864 IVMLTKLREMGREKCHQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRT 1923
Query: 2181 IKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPN--DAGPIISHCSAGIGRTGAFIVIDC 2354
I+ Q+T WP+ GVP F+ F+ +V GPI HCSAG+GRTG FI +
Sbjct: 1924 IRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGPIAVHCSAGVGRTGVFIALSI 1983
Query: 2355 MLERLRYDNTVDIYGCVTALRAQRSYMVQTE 2447
LER+R++ VD++ V LR QR MVQTE
Sbjct: 1984 ALERMRFEGVVDLFQTVKTLRTQRPAMVQTE 2014
Score = 192 bits (489), Expect = 4e-47
Identities = 93/232 (40%), Positives = 136/232 (58%)
Frame = +3
Query: 2637 ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNE 2816
+NL +N+PKNR + + YD +RVI+ + G GSDYINA+++DGY+++ AYIATQ P E
Sbjct: 1499 SNLEINKPKNRYANVIAYDHSRVILAAVDGIPGSDYINANYVDGYRKQNAYIATQGPLPE 1558
Query: 2817 TAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYH 2996
T +DFWR +WE + I M+ R E+ + +C YWP GM+ V + ++ Y
Sbjct: 1559 TLSDFWRMVWEQRTCTIIMMTRLEEKSRVKCEQYWPARGTHTYGMIQVTLLDTVELATYT 1618
Query: 2997 LREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVH 3176
+R F + + E R VRQF M WPD G P L F+ +V + +GP+ VH
Sbjct: 1619 IRTFALYKNGSSEKREVRQFQLMAWPDHGVPECPTPILAFLRRVKACHPPD--SGPMVVH 1676
Query: 3177 CCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF 3332
C +G GRT FI + +L+RM+ E VD++ V +R +R M+Q EQY F
Sbjct: 1677 CSAGVGRTGCFIVIDAMLERMKHEKSVDIYGHVTCMRAQRNYMVQTEEQYIF 1728
>gi|452199|dbj|BAA03003.1| MPTPdelta [Mus musculus]
Length = 1291
Score = 679 bits (1751), Expect = 0.0
Identities = 332/618 (53%), Positives = 436/618 (69%), Gaps = 1/618 (0%)
Frame = +3
Query: 1530 ESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVSHPAVPIAELANHIERLRMNN 1709
ES LP S + + PV + L N SHP +PI ELA+HIERL+ N+
Sbjct: 678 ESDSRKSSLPNSKEVPSHHPTDPVELRRL--NFQTPGMASHPPIPILELADHIERLKAND 735
Query: 1710 NAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINA 1889
N F E+ESI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DY+NA
Sbjct: 736 NLKFSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYVNA 795
Query: 1890 NYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRG 2069
NY+DGY K +YIATQG LPETF DFWRM+W EQ T+VM+T LEERSRVKCDQYWPSRG
Sbjct: 796 NYIDGYRKQNAYIATQGSLPETFGDFWRMIW-EQEATVVMMTKLEERSRVKCDQYWPSRG 854
Query: 2070 TATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLI 2249
T T+G ++VTLL++V L H + G E R+++ Q+TAWPDHGVP+HPTP
Sbjct: 855 TETHGLVQVTLLDTVEL-HILCPDICTLNNGSSEKRKVRQFQFTAWPDHGVPEHPTPVPS 913
Query: 2250 FLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRS 2429
FL + L+P DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+
Sbjct: 914 FLTESQNLHPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRN 973
Query: 2430 YMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTT 2606
YMVQTE+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L +
Sbjct: 974 YMVQTEDQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLAS 1033
Query: 2607 LKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGA 2786
K ++R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS++DGY+++ A
Sbjct: 1034 SKAHTSRFISANLPCNKFKNRLVNIMPYESGRVCLQPIRGVEGSDYINASFLDGYRQQKA 1093
Query: 2787 YIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEP 2966
YIATQ P ET DFWR +WEHNS I+ ML + E G+E+C YWP E + VV+P
Sbjct: 1094 YIATQGPLAETTEDFWRMLWEHNSTIVVMLTKLREMGREKCHQYWPAERSARYQYFVVDP 1153
Query: 2967 MAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQ 3146
MAEY+M Y LR R S + + RTVRQF F +WP+ G P + + F+DF+ QVH T Q
Sbjct: 1154 MAEYNMPQYILRNSR-SRMPGIQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQ 1212
Query: 3147 FGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQY 3326
FG GPI+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY
Sbjct: 1213 FGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQY 1272
Query: 3327 HFXXXXXXXXXXXXDNFS 3380
F D+++
Sbjct: 1273 QFCYRAALEYLGSFDHYA 1290
Score = 43.5 bits (101), Expect = 0.034
Identities = 65/256 (25%), Positives = 112/256 (43%), Gaps = 20/256 (7%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + S+ + H+P N + P ID
Sbjct: 118 PGTPVVTESTATSITLT-WDSGNPGPVSYYI-IQHKPKNSEE-------PYKEIDGIATT 168
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDPP-TVLESVTPTYMVQNLRVLWKTSNSVQ 368
R++V L+ + Y F V+AV N +GP S+P T TP+ ++++ +S ++
Sbjct: 169 RYSVAG-LSPYSDYEFRVVAVNNIGRGPASEPVLTQTSEQTPSSAPRDVQARMLSSTTIL 227
Query: 369 LTW----EYNGPRNVGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKH---RE 512
+ W E NG + G+ V +T +++ H + + ++T G V +K +
Sbjct: 228 VQWKEPEEPNG-QIQGYRVYYTMDPTQHVNNWMKHNVADSQITT--IGNLVPQKTYSVKV 284
Query: 513 YLWTNLRPHMMYT-IHVGVRTLPPGAR---KYWPQEVVTITDPTGPPFVDV---PKLVDS 671
+T++ + + I V +T PG K P+ +I PP D +LVD
Sbjct: 285 LAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIASYELVDR 344
Query: 672 SGTQPGQQMIRLTPAT 719
G Q +Q I + P T
Sbjct: 345 DGDQGEEQRITIEPGT 360
>gi|7511703|pir||T31093 probable protein-tyrosine-phosphatase (EC
3.1.3.48) - medicinal leech
gi|2695657|gb|AAB91461.1| receptor tyrosine phosphatase [Hirudo
medicinalis]
Length = 1437
Score = 676 bits (1744), Expect = 0.0
Identities = 326/616 (52%), Positives = 438/616 (70%), Gaps = 10/616 (1%)
Frame = +3
Query: 1512 NGNHHMESSMDLYPLPTSHSRSNGYAPVPVAIPSLPNNGNNMTTVS---HPAVPIAELAN 1682
N N + E++ Y LP ++ A + + P+ P T + HP++PI+E A
Sbjct: 804 NRNRNRENNSKRYLLPRQPTKIMPSADLSIH-PTDPVRRLQYQTQAMACHPSIPISEFAA 862
Query: 1683 HIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEG 1862
H+E+L+ N A F E+ESIE GQ FTWE SS D NK KNRYANV AYDHSRVVL ++EG
Sbjct: 863 HVEQLKACNGARFSQEYESIEPGQQFTWEASSLDCNKPKNRYANVIAYDHSRVVLQSLEG 922
Query: 1863 YPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVK 2042
G DYINAN++DGY K +YIATQGPLPETF DFWRMVWE++ TIVM+T LEER R+K
Sbjct: 923 ISGSDYINANFMDGYRKSNAYIATQGPLPETFVDFWRMVWEQRVTTIVMMTKLEERGRIK 982
Query: 2043 CDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGV 2222
CDQYWP+RGT YG + VTL++ V LA YT+RT + G+ E E+K Q+TAWPDHGV
Sbjct: 983 CDQYWPNRGTEVYGPMHVTLVDVVELAIYTLRTFIVTKTGQQERIEVKQFQFTAWPDHGV 1042
Query: 2223 PDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGC 2402
P+HPT L+F +RV++ + D+GP++ HCSAG+GRTG FIV+D MLER ++ T+D+YG
Sbjct: 1043 PEHPTALLMFHRRVRSFHTVDSGPMVVHCSAGVGRTGRFIVVDRMLERALHEKTIDVYGH 1102
Query: 2403 VTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEVPASRLHQHLH-ILSQPSADQLSGI 2579
VT LRAQR+YMVQTE+QYIF+HDA+L+ V SG TEVPA L+ H+ ++S S L+ +
Sbjct: 1103 VTCLRAQRNYMVQTEDQYIFVHDAILEGVTSGCTEVPARNLYAHMQKLMSLESGSNLTLM 1162
Query: 2580 DMEFRHLTTLKWTSNRCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASW 2759
++EF+ L +K +S++ A+LP N+ KNR+++ +PY+S+RV ++L+ G DGSDYINA++
Sbjct: 1163 EVEFKKLANIKTSSSQFASASLPSNKFKNRLVNILPYESSRVTLQLIRGVDGSDYINANF 1222
Query: 2760 IDGYKERGAYIATQAPTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGV 2939
IDGY+ + AYIATQ P T DFWR +WEHNS I+ MLV+ E G+E+C YWP E
Sbjct: 1223 IDGYRYKKAYIATQGPLASTTEDFWRMLWEHNSTIVVMLVKLREMGREKCLQYWPSERSA 1282
Query: 2940 QVGMLVVEPMAEYDMKHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFV 3119
+ VV+PM EY+M Y LREF+++D + RT+RQF F +WP+ G P + + F+DF+
Sbjct: 1283 RYQYFVVDPMVEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVPKSGEGFVDFI 1342
Query: 3120 TQVHNTYAQFGCTGPITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTER- 3296
QVH T QFG GPITVHC +G RT VFIALS++L+RMR E VVD+F TV+LLRT+R
Sbjct: 1343 GQVHKTKEQFGQDGPITVHCGAGVSRTGVFIALSVVLERMRYEGVVDLFQTVRLLRTQRP 1402
Query: 3297 -----QNMIQEPEQYH 3329
+ +Q PE ++
Sbjct: 1403 CCVKLRLQVQTPEDHY 1418
Score = 176 bits (446), Expect = 3e-42
Identities = 90/232 (38%), Positives = 131/232 (55%)
Frame = +3
Query: 2637 ANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNE 2816
++L N+PKNR + + YD +RV+++ L G GSDYINA+++DGY++ AYIATQ P E
Sbjct: 893 SSLDCNKPKNRYANVIAYDHSRVVLQSLEGISGSDYINANFMDGYRKSNAYIATQGPLPE 952
Query: 2817 TAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYH 2996
T DFWR +WE I M+ + ERG+ +C YWP G + V + ++ Y
Sbjct: 953 TFVDFWRMVWEQRVTTIVMMTKLEERGRIKCDQYWPNRGTEVYGPMHVTLVDVVELAIYT 1012
Query: 2997 LREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVH 3176
LR F ++ +E V+QF F WPD G P L F +V + + +GP+ VH
Sbjct: 1013 LRTFIVTKTGQQERIEVKQFQFTAWPDHGVPEHPTALLMFHRRVRSFHTVD--SGPMVVH 1070
Query: 3177 CCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHF 3332
C +G GRT FI + +L+R E +DV+ V LR +R M+Q +QY F
Sbjct: 1071 CSAGVGRTGRFIVVDRMLERALHEKTIDVYGHVTCLRAQRNYMVQTEDQYIF 1122
Score = 42.4 bits (98), Expect = 0.077
Identities = 52/263 (19%), Positives = 109/263 (40%), Gaps = 10/263 (3%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
PPT++ + ++ V W + + + D + WK +D ++P
Sbjct: 423 PPTDILIRRVHSTEMEVSWVAPTPLRGVSGYRIYYNEVALSDIDMWK-----FVDVDSP- 476
Query: 192 RFAVVSDLNAHKPYAFCVLAVK----NNRQGPCSDPP--TVLESVTPTYMVQNLRVLWKT 353
+ +++ +PY+ + V+ + G S+ LE P MV+ +
Sbjct: 477 -YTTTLEISNLEPYSVYTVRVRAKYSDGSFGNLSETAYSNKLEDEHPE-MVREFQSQVLD 534
Query: 354 SNSVQLTWEYNGPRNVG---FYVNHTGRKDYVN-HELQEKTMSTPGFGQDVDEKHREYLW 521
S ++ L W+ PR G + + + GRK + H E+T+ V++ + +
Sbjct: 535 SKTIVLQWK--APRKAGLSRYQIEYEGRKRVSSDHTGLEETVIDTKKSFQVEKGAQSFRI 592
Query: 522 TNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMI 701
NL + +Y+I++ + + P ++ T P+ PP ++ P L+ +G +
Sbjct: 593 ENLLSNTLYSINITAKFIDGITGP--PYQLRVETSPSDPPVLEAPTLLRVTGDLLVVMRL 650
Query: 702 RLTPATEEYGPISHYWIILVPAN 770
L Y + Y++++VPAN
Sbjct: 651 SLPSVQPMYDNV-QYYVVVVPAN 672
>gi|50761732|ref|XP_429156.1| PREDICTED: similar to protein tyrosine
phosphatase, receptor type, D isoform 2 precursor;
protein tyrosine phosphatase, receptor type, delta
polypeptide; protein tyrosine phosphatase delta, partial
[Gallus gallus]
Length = 1725
Score = 675 bits (1742), Expect = 0.0
Identities = 318/552 (57%), Positives = 412/552 (74%), Gaps = 1/552 (0%)
Frame = +3
Query: 1728 EFESIETGQHFTWEHSSADMNKHKNRYANVAAYDHSRVVLSNVEGYPGMDYINANYVDGY 1907
+F SI+ GQ FTWEHS+ ++NK KNRYANV AYDHSRV+LS +EG PG DYINANY+DGY
Sbjct: 1178 KFMSIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVLLSAIEGIPGSDYINANYIDGY 1237
Query: 1908 DKPRSYIATQGPLPETFSDFWRMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGD 2087
K +YIATQG LPETF DFWRM+WE++ T+VM+T LEERSRVKCDQYWPSRGT TYG
Sbjct: 1238 RKQNAYIATQGALPETFGDFWRMMWEQRGATVVMMTKLEERSRVKCDQYWPSRGTETYGL 1297
Query: 2088 IEVTLLESVHLAHYTMRTMRLKMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVK 2267
I+VTLL++V LA Y +RT L G E RE++ Q+TAWPDHGVP+HPTPFL FL+RVK
Sbjct: 1298 IQVTLLDTVELATYCVRTFALYKNGSSEKREVRQFQFTAWPDHGVPEHPTPFLAFLRRVK 1357
Query: 2268 TLNPNDAGPIISHCSAGIGRTGAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTE 2447
T NP DAGP++ HCSAG+GRTG FIVID MLER++++ TVDIYG VT +RAQR+YMVQTE
Sbjct: 1358 TCNPPDAGPMVVHCSAGVGRTGCFIVIDAMLERIKHEKTVDIYGHVTLMRAQRNYMVQTE 1417
Query: 2448 EQYIFIHDAVLDAVNSGSTEVPASRLHQHLHILSQ-PSADQLSGIDMEFRHLTTLKWTSN 2624
+QYIFIHDA+L+AV G+TEVPA L+ ++ L+Q + + ++G+++EF+ L + K ++
Sbjct: 1418 DQYIFIHDALLEAVTCGNTEVPARNLYAYIQKLTQIETGENVTGMELEFKRLASSKAHTS 1477
Query: 2625 RCTVANLPVNRPKNRMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQA 2804
R ANLP N+ KNR+++ +PY+S RV ++ + G +GSDYINAS+ DGY+++ AYIATQ
Sbjct: 1478 RFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINASFADGYRQQKAYIATQG 1537
Query: 2805 PTNETAADFWRAIWEHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDM 2984
P ET DFWR +WEHNS I+ ML + E G+ YWP E + VV+PMAEY+M
Sbjct: 1538 PLAETTEDFWRMLWEHNSTIVVMLTKLREMGR-----YWPAERSARYQYFVVDPMAEYNM 1592
Query: 2985 KHYHLREFRISDINTREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGP 3164
Y LREF+++D + RTVRQF F +WP+ G P + + F+DF+ QVH T QFG GP
Sbjct: 1593 PQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEGFIDFIGQVHKTKEQFGQDGP 1652
Query: 3165 ITVHCCSGAGRTAVFIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXX 3344
I+VHC +G GRT VFI LSI+L+RMR E VVD+F TVK+LRT+R M+Q +QY F
Sbjct: 1653 ISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVKMLRTQRPAMVQTEDQYQFCYRA 1712
Query: 3345 XXXXXXXXDNFS 3380
D+++
Sbjct: 1713 ALEYLGSFDHYA 1724
Score = 40.0 bits (92), Expect = 0.38
Identities = 58/273 (21%), Positives = 107/273 (38%), Gaps = 9/273 (3%)
Frame = +3
Query: 12 PPTNVRVEATSNSTAVVQWDFESQKADSFVVKYMHEPGNRMDTEKWKQLPVVSIDKENPK 191
P T V E+T+ S + WD + + S+ YM + + E +K++ V+ + +
Sbjct: 272 PGTPVVTESTATSITLT-WDSGNPEPVSY---YMIQLKPKNSEEPYKEIDGVATTRYS-- 325
Query: 192 RFAVVSDLNAHKPYAFCVLAVKNNRQGPCSDP-PTVLESVTPTYMVQNLRVLWKTSNSVQ 368
V+ L+ + Y F V+AV N +GP S+P T P+ +N++ +S ++
Sbjct: 326 ----VAGLSPYSEYEFRVVAVNNIGRGPPSEPVSTRTSEQAPSSAPRNVQARMLSSTTIL 381
Query: 369 LTWEYNGPRN---VGFYVNHT-----GRKDYVNHELQEKTMSTPGFGQDVDEKHREYLWT 524
+ WE N G+ V +T ++ H + + ++T G
Sbjct: 382 VQWEEPEEPNGQIQGYRVYYTMDPTQHVNSWLKHNVADSHITTIG--------------- 426
Query: 525 NLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQQMIR 704
NL P Y++ V T +V+T T G P ++ + I
Sbjct: 427 NLVPQKTYSVKVLAFTSVGDGPLSSDIQVITQTGVPGQP-------LNFKAEPESETSIL 479
Query: 705 LTPATEEYGPISHYWIILVPANYSTEDVVNLDP 803
L+ IS Y ++ + E V+ +P
Sbjct: 480 LSWTPPRSDTISSYELVYKDGEHGEEQRVSTEP 512
>gi|7511704|pir||T30938 receptor tyrosine phosphatase - medicinal
leech
gi|2695655|gb|AAB91460.1| receptor tyrosine phosphatase [Hirudo
medicinalis]
Length = 2051
Score = 642 bits (1656), Expect = 0.0
Identities = 308/598 (51%), Positives = 409/598 (67%), Gaps = 19/598 (3%)
Frame = +3
Query: 1644 VSHPAVPIAELANHIERLRMNNNAGFQSEFESIETGQHFTWEHSSADMNKHKNRYANVAA 1823
V+HP + + +LA H+E LR ++N F E+ESI+ GQ FTWE S+ ++NK KNRYANV A
Sbjct: 1453 VNHPPIRVEDLATHLEALRASDNNRFSLEYESIDPGQQFTWEASNLEVNKSKNRYANVIA 1512
Query: 1824 YDHSRVVLSNV-----------EGYPGMDYINANYVDGYDKPRSYIATQGPLPETFSDFW 1970
YDHSRV L + + PG DYINAN++DG+ K +YIATQGP+ ET DFW
Sbjct: 1513 YDHSRVTLHPLPQASSTYHPPGQVVPGSDYINANFLDGFRKQNAYIATQGPMAETSVDFW 1572
Query: 1971 RMVWEEQSVTIVMLTNLEERSRVKCDQYWPSRGTATYGDIEVTLLESVHLAHYTMRTMRL 2150
RMVWE QS IVM+T LEER RVKCDQYWPSRG+ +YG ++V L++ + LA YTMRT ++
Sbjct: 1573 RMVWERQSPVIVMMTKLEERGRVKCDQYWPSRGSESYGSLQVNLVDVIELATYTMRTFQM 1632
Query: 2151 KMVGEPEVREIKHLQYTAWPDHGVPDHPTPFLIFLKRVKTLNPNDAGPIISHCSAGIGRT 2330
E RE++H Q+TAWPD+GVP+H P L+F + + +P D+GPI+ HCSAG+GRT
Sbjct: 1633 SSEFNSEKREVRHFQFTAWPDYGVPEHAAPLLLFHEEGQVHDPPDSGPIVVHCSAGVGRT 1692
Query: 2331 GAFIVIDCMLERLRYDNTVDIYGCVTALRAQRSYMVQTEEQYIFIHDAVLDAVNSGSTEV 2510
G F+V+D MLER+++ +VDIYG VT LRAQR+YMVQTE+QYIFIH A+L+AV SG+TEV
Sbjct: 1693 GVFVVLDSMLERIKHTGSVDIYGHVTCLRAQRNYMVQTEDQYIFIHAAILEAVTSGNTEV 1752
Query: 2511 PASRLHQHLHILSQP--------SADQLSGIDMEFRHLTTLKWTSNRCTVANLPVNRPKN 2666
PA L H+ L +P + ++GI+ EF+ L++ K + + ANL N+ KN
Sbjct: 1753 PARNLFAHMQKLLEPLTITSQSGHSTTITGIEAEFKKLSSGKTSLSSFASANLSCNKQKN 1812
Query: 2667 RMLSAVPYDSNRVIMRLLPGADGSDYINASWIDGYKERGAYIATQAPTNETAADFWRAIW 2846
R+++ +PY++ RV ++ + G DGSDYINAS+IDGY+ R AYIATQ P +T DFWRA+W
Sbjct: 1813 RLVNVLPYETTRVCLQPIRGVDGSDYINASFIDGYRYRRAYIATQGPLPDTVEDFWRALW 1872
Query: 2847 EHNSPIIAMLVRTNERGQEQCSDYWPLETGVQVGMLVVEPMAEYDMKHYHLREFRISDIN 3026
E N II ML + E G+E C YWP E + VV+P+AEY+M Y LREF+++D
Sbjct: 1873 ESNCNIIVMLTKLREMGREMCHQYWPSERSARYQYFVVDPLAEYNMPQYILREFKVTDAR 1932
Query: 3027 TREVRTVRQFHFMEWPDVGKPHTADHFLDFVTQVHNTYAQFGCTGPITVHCCSGAGRTAV 3206
+ RT+RQF +WP+ G P T D F+DF+ Q H T QFG GPI VHC +G GRT V
Sbjct: 1933 DGQSRTMRQFQLTDWPEQGVPSTGDGFIDFIGQTHKTKEQFGQEGPIAVHCSAGVGRTGV 1992
Query: 3207 FIALSIILDRMRAEHVVDVFTTVKLLRTERQNMIQEPEQYHFXXXXXXXXXXXXDNFS 3380
FI LSI+L+RMR E VDVF TV +LRT+R M+Q EQY F D+++
Sbjct: 1993 FITLSIVLERMRFEGAVDVFQTVNVLRTQRPGMVQTEEQYAFCYRAALEYLGSFDHYT 2050
Score = 35.8 bits (81), Expect = 7.2
Identities = 58/264 (21%), Positives = 99/264 (36%), Gaps = 14/264 (5%)
Frame = +3
Query: 15 PTNVRVEATSNSTAVVQWDFESQKAD----SFVVKYMHEPGNRMDTEKWKQLPVVSIDKE 182
P N+R+ TS ++ V WD K + + Y P +D KW SI
Sbjct: 1036 PLNIRLRQTSVTSMEVSWDELHGKNPLNVLGYRIYYSSTPNANLD--KW------SIIDI 1087
Query: 183 NPKRFAVVSDLNAHKPYAFCVLA-VKNNRQGPCSDPPTVLESVTPTYMVQNLRVLWKTSN 359
P A V L+ Y+ + A + R G SD +PT + +R ++ S
Sbjct: 1088 GPGTSAEVHGLDPSTTYSVRIRARGSDGRFGILSD------QSSPTDWIMKIRKQFQVS- 1140
Query: 360 SVQLTW---EYNG---PRNVG---FYVNHTGRKDYVNHELQEKTMSTPGFGQDVDEKHRE 512
S +LT Y+ PR G + + + G + + E T P + ++ R
Sbjct: 1141 SAELTTPGPSYSSGRPPRKPGVLRYKLEYMGVRKTRDFSGMEDTTVDPRKEVTLQKEERS 1200
Query: 513 YLWTNLRPHMMYTIHVGVRTLPPGARKYWPQEVVTITDPTGPPFVDVPKLVDSSGTQPGQ 692
L +YT ++ R + + P + + + +D P + Q
Sbjct: 1201 RSLDELMSRTLYTFNISARFID---GTWGPPTTIHVETNSEETILDPPSFIRPLSDQ--M 1255
Query: 693 QMIRLTPATEEYGPISHYWIILVP 764
+R+ PA + G + Y I +VP
Sbjct: 1256 VSLRVKPAADVLGKVLQYLIFVVP 1279