Homology by BLASTX


BLASTX 2.2.4 [Aug-26-2002]
Query= F36H5_12
         (2466 letters)

Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
           1,967,186 sequences; 661,712,633 total letters


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|17533755|ref|NP_494075.1| Meprin/TRAF-like MATH family member...  1660   0.0
gi|7500678|pir||T25744 hypothetical protein F36H5.1 - Caenorhabd...  1426   0.0
gi|7500679|pir||T25743 hypothetical protein F36H5.2 - Caenorhabd...  1182   0.0
gi|32564805|ref|NP_872003.1| Meprin/TRAF-like MATH family member...  1031   0.0
gi|17531653|ref|NP_494076.1| Meprin/TRAF-like MATH family member...   819   0.0
gi|7495680|pir||T32337 hypothetical protein C08F1.4 - Caenorhabd...   765   0.0
gi|32564807|ref|NP_872004.1| Meprin/TRAF-like MATH family member...   688   0.0
gi|17533759|ref|NP_494073.1| Meprin/TRAF-like MATH family member...   654   0.0
gi|32564795|ref|NP_494077.2| Meprin/TRAF-like MATH family member...   651   0.0
gi|7495681|pir||T32338 hypothetical protein C08F1.5 - Caenorhabd...   651   0.0
gi|34365961|gb|AAK31514.2| Hypothetical protein F36H5.3 [Caenorh...   516   e-145
gi|17536299|ref|NP_494181.1| Meprin/TRAF-like MATH family member...   348   3e-94
gi|25353954|pir||H88065 protein T16A1.1 [imported] - Caenorhabdi...   348   3e-94
gi|17531649|ref|NP_494080.1| predicted CDS, Meprin/TRAF-like MAT...   310   8e-83
gi|32564799|ref|NP_872002.1| Meprin/TRAF-like MATH family member...   297   7e-79
gi|48060508|gb|AAK31402.2| Hypothetical protein C08F1.1 [Caenorh...   274   6e-72
gi|7511050|pir||T32417 hypothetical protein ZK250.6 - Caenorhabd...   248   6e-64
gi|17537845|ref|NP_494136.1| predicted CDS, Meprin/TRAF-like MAT...   248   6e-64
gi|32565235|ref|NP_494144.2| Meprin/TRAF-like MATH family member...   230   1e-58
gi|17532359|ref|NP_494146.1| Meprin/TRAF-like MATH family member...   220   1e-55
gi|17532441|ref|NP_494117.1| predicted CDS, Meprin/TRAF-like MAT...   220   1e-55
gi|17532361|ref|NP_494145.1| Meprin/TRAF-like MATH family member...   218   5e-55
gi|17532443|ref|NP_494116.1| Meprin/TRAF-like MATH family member...   216   2e-54
gi|17537849|ref|NP_494139.1| predicted CDS, Meprin/TRAF-like MAT...   208   4e-52
gi|49035196|gb|AAB70959.2| Hypothetical protein C46F9.4 [Caenorh...   205   4e-51
gi|17532445|ref|NP_494115.1| Meprin/TRAF-like MATH precursor fam...   205   4e-51
gi|17531819|ref|NP_494108.1| predicted CDS, Meprin/TRAF-like MAT...   189   3e-46
gi|17531809|ref|NP_494101.1| predicted CDS, Meprin/TRAF-like MAT...   186   3e-45
gi|32564803|ref|NP_494074.2| Meprin/TRAF-like MATH family member...   182   3e-44
gi|7507464|pir||T33390 hypothetical protein T08E11.4 - Caenorhab...   182   4e-44
gi|25148479|ref|NP_494086.2| Meprin/TRAF-like MATH family member...   182   4e-44
gi|7497506|pir||T32352 hypothetical protein C46F9.1 - Caenorhabd...   181   6e-44
gi|17536131|ref|NP_494087.1| Meprin/TRAF-like MATH family member...   179   2e-43
gi|17536129|ref|NP_494088.1| ubiquitin specific protease 7 like ...   177   8e-43
gi|17531823|ref|NP_494110.1| predicted CDS, Meprin/TRAF-like MAT...   177   1e-42
gi|17537847|ref|NP_494138.1| predicted CDS, Meprin/TRAF-like MAT...   171   1e-40
gi|49035211|gb|AAB93663.2| Hypothetical protein C16C4.13 [Caenor...   161   6e-38
gi|17534235|ref|NP_494119.1| Meprin/TRAF-like MATH family member...   159   2e-37
gi|17531821|ref|NP_494109.1| predicted CDS, Meprin/TRAF-like MAT...   158   5e-37
gi|17531829|ref|NP_494103.1| Meprin/TRAF-like MATH family member...   151   6e-35
gi|32699242|gb|AAB93661.2| Hypothetical protein C16C4.4 [Caenorh...   149   2e-34
gi|32564817|ref|NP_493983.3| Meprin/TRAF-like MATH family member...   147   9e-34
gi|17535627|ref|NP_494182.1| Meprin/TRAF-like MATH family member...   147   1e-33
gi|17532337|ref|NP_494201.1| Meprin/TRAF-like MATH family member...   142   5e-32
gi|17531825|ref|NP_494111.1| predicted CDS, Meprin/TRAF-like MAT...   132   3e-29
gi|17531827|ref|NP_494112.1| predicted CDS, Meprin/TRAF-like MAT...   128   6e-28
gi|17531807|ref|NP_494102.1| Meprin/TRAF-like MATH family member...   125   4e-27
gi|7511049|pir||T32415 hypothetical protein ZK250.5 - Caenorhabd...   120   1e-25
gi|17531817|ref|NP_494107.1| predicted CDS, Meprin/TRAF-like MAT...   117   1e-24
gi|17535637|ref|NP_494187.1| Meprin/TRAF-like MATH family member...   115   4e-24
gi|17532357|ref|NP_494147.1| predicted CDS, Meprin/TRAF-like MAT...   112   4e-23
gi|17531815|ref|NP_494106.1| predicted CDS, Meprin/TRAF-like MAT...   105   5e-21
gi|17531805|ref|NP_494105.1| predicted CDS, Meprin/TRAF-like MAT...   105   5e-21
gi|32565229|ref|NP_494113.2| predicted CDS, Meprin/TRAF-like MAT...   105   7e-21
gi|7496112|pir||T31946 hypothetical protein C16C4.2 - Caenorhabd...   105   7e-21
gi|17531831|ref|NP_494104.1| predicted CDS, Meprin/TRAF-like MAT...   103   2e-20
gi|49035137|gb|AAB71066.2| Hypothetical protein R52.9 [Caenorhab...    84   2e-14
gi|32564788|ref|NP_494118.2| Meprin/TRAF-like MATH family member...    84   2e-14
gi|17531221|ref|NP_494164.1| predicted CDS, Meprin/TRAF-like MAT...    84   2e-14
gi|39589941|emb|CAE60939.1| Hypothetical protein CBG04662 [Caeno...    84   2e-14
gi|17534635|ref|NP_494158.1| Meprin/TRAF-like MATH and BTB/POZ d...    82   8e-14
gi|7503929|pir||T32800 hypothetical protein F52C6.7 - Caenorhabd...    80   2e-13
gi|32564786|ref|NP_494121.2| Meprin/TRAF-like MATH and BTB/POZ d...    80   2e-13
gi|17534633|ref|NP_494157.1| predicted CDS, Meprin/TRAF-like MAT...    79   5e-13
gi|17535641|ref|NP_494189.1| Meprin/TRAF-like MATH and BTB/POZ d...    79   7e-13
gi|17535643|ref|NP_494190.1| Meprin/TRAF-like MATH and BTB/POZ d...    79   7e-13
gi|25395428|pir||H88066 protein R52.10 [imported] - Caenorhabdit...    79   7e-13
gi|39579187|emb|CAE56675.1| Hypothetical protein CBG24449 [Caeno...    77   3e-12
gi|17537305|ref|NP_494526.1| Meprin/TRAF-like MATH and BTB/POZ d...    76   3e-12
gi|17537309|ref|NP_494524.1| Meprin/TRAF-like MATH and BTB/POZ d...    75   7e-12
gi|17536119|ref|NP_494001.1| Meprin/TRAF-like MATH family member...    75   7e-12
gi|38176043|gb|AAC26311.2| Hypothetical protein T07H3.3 [Caenorh...    75   7e-12
gi|17533825|ref|NP_494287.1| Meprin/TRAF-like MATH and BTB/POZ d...    74   1e-11
gi|17509289|ref|NP_492837.1| predicted CDS, Meprin/TRAF-like MAT...    74   2e-11
gi|17534631|ref|NP_494156.1| Meprin/TRAF-like MATH and BTB/POZ d...    74   2e-11
gi|17552122|ref|NP_498694.1| Meprin/TRAF-like MATH and BTB/POZ d...    73   4e-11
gi|17535639|ref|NP_494188.1| predicted CDS, Meprin/TRAF-like MAT...    72   8e-11
gi|17535623|ref|NP_494192.1| Meprin/TRAF-like MATH and BTB/POZ d...    71   1e-10
gi|17534621|ref|NP_494150.1| predicted CDS, Meprin/TRAF-like MAT...    71   1e-10
gi|38175983|gb|AAB94977.2| Hypothetical protein F52C6.11 [Caenor...    71   1e-10
gi|50727046|gb|AAC67450.2| Hypothetical protein F59H5.3 [Caenorh...    70   2e-10
gi|17534613|ref|NP_494286.1| Meprin/TRAF-like MATH and BTB/POZ d...    70   2e-10
gi|17534241|ref|NP_494122.1| Meprin/TRAF-like MATH and BTB/POZ d...    70   2e-10
gi|39582485|emb|CAE66576.1| Hypothetical protein CBG11893 [Caeno...    66   5e-09
gi|39584717|emb|CAE72470.1| Hypothetical protein CBG19644 [Caeno...    65   6e-09
gi|39584614|emb|CAE72367.1| Hypothetical protein CBG19518 [Caeno...    65   1e-08
gi|39579564|emb|CAE56421.1| Hypothetical protein CBG24113 [Caeno...    64   2e-08
gi|17537311|ref|NP_494523.1| Meprin/TRAF-like MATH and BTB/POZ d...    64   2e-08
gi|17534245|ref|NP_494124.1| Meprin/TRAF-like MATH and BTB/POZ d...    61   1e-07
gi|7499081|pir||T32791 hypothetical protein F14D2.8 - Caenorhabd...    60   2e-07
gi|32564764|ref|NP_494512.2| Meprin/TRAF-like MATH and BTB/POZ d...    60   2e-07
gi|17533573|ref|NP_496788.1| Meprin/TRAF-like MATH and BTB/POZ d...    60   2e-07
gi|7499077|pir||T32792 hypothetical protein F14D2.4 - Caenorhabd...    60   2e-07
gi|32564762|ref|NP_494513.2| Meprin/TRAF-like MATH and BTB/POZ d...    60   2e-07
gi|39584714|emb|CAE72467.1| Hypothetical protein CBG19641 [Caeno...    60   2e-07
gi|25395396|pir||B88035 protein M01D1.2 [imported] - Caenorhabdi...    59   4e-07
gi|25152600|ref|NP_494123.2| Meprin/TRAF-like MATH and BTB/POZ d...    59   4e-07
gi|39579541|emb|CAE56433.1| Hypothetical protein CBG24133 [Caeno...    59   6e-07
gi|39584716|emb|CAE72469.1| Hypothetical protein CBG19643 [Caeno...    59   6e-07
gi|17536115|ref|NP_494006.1| BTB/POZ domain and Meprin/TRAF-like...    59   7e-07
gi|7507414|pir||T33379 hypothetical protein T07H3.1 - Caenorhabd...    59   7e-07
gi|17531215|ref|NP_494161.1| Meprin/TRAF-like MATH and BTB/POZ d...    57   2e-06
gi|48060523|gb|AAB66041.2| Hypothetical protein B0047.1 [Caenorh...    57   2e-06
gi|17531627|ref|NP_494007.1| Meprin/TRAF-like MATH and BTB/POZ d...    57   2e-06
gi|7495667|pir||T32353 hypothetical protein C08E3.3 - Caenorhabd...    57   2e-06
gi|17536117|ref|NP_494004.1| predicted CDS, BTB/POZ domain and M...    56   5e-06
gi|39579624|emb|CAE74563.1| Hypothetical protein CBG22325 [Caeno...    55   1e-05
gi|17533141|ref|NP_494635.1| Meprin/TRAF-like MATH and BTB/POZ d...    54   1e-05
gi|7503931|pir||T32802 hypothetical protein F52C6.9 - Caenorhabd...    54   1e-05
gi|39579935|emb|CAE73861.1| Hypothetical protein CBG21446 [Caeno...    54   2e-05
gi|39582564|emb|CAE63883.1| Hypothetical protein CBG08449 [Caeno...    54   2e-05
gi|17534629|ref|NP_494155.1| Meprin/TRAF-like MATH and BTB/POZ d...    54   2e-05
gi|39580500|emb|CAE70470.1| Hypothetical protein CBG17057 [Caeno...    52   9e-05
gi|39579700|emb|CAE56409.1| Hypothetical protein CBG24100 [Caeno...    51   1e-04
gi|39584713|emb|CAE72466.1| Hypothetical protein CBG19640 [Caeno...    51   1e-04
gi|17534227|ref|NP_494129.1| kelch motif containing protein like...    50   2e-04
gi|39579981|emb|CAE74194.1| Hypothetical protein CBG21869 [Caeno...    50   3e-04
gi|39585582|emb|CAE65342.1| Hypothetical protein CBG10279 [Caeno...    50   3e-04
gi|32564811|ref|NP_494005.2| Meprin/TRAF-like MATH family member...    50   3e-04
gi|39588989|emb|CAE69619.1| Hypothetical protein CBG15853 [Caeno...    49   4e-04
gi|17534237|ref|NP_494120.1| Meprin/TRAF-like MATH family member...    49   6e-04
gi|39579263|emb|CAE56960.1| Hypothetical protein CBG24810 [Caeno...    49   6e-04
gi|17534067|ref|NP_494049.1| Meprin/TRAF-like MATH and BTB/POZ d...    49   7e-04
gi|39584615|emb|CAE72368.1| Hypothetical protein CBG19519 [Caeno...    47   0.002
gi|17534247|ref|NP_494125.1| Meprin/TRAF-like MATH and BTB/POZ d...    47   0.002
gi|39582556|emb|CAE63875.1| Hypothetical protein CBG08441 [Caeno...    47   0.003
gi|39582381|emb|CAE74765.1| Hypothetical protein CBG22594 [Caeno...    47   0.003
gi|39578867|emb|CAE56206.1| Hypothetical protein CBG23830 [Caeno...    46   0.004
gi|39591359|emb|CAE73413.1| Hypothetical protein CBG20855 [Caeno...    45   0.006
gi|39591367|emb|CAE73421.1| Hypothetical protein CBG20864 [Caeno...    45   0.008
gi|17537313|ref|NP_494522.1| predicted CDS, kelch motif containi...    45   0.008
gi|38176033|gb|AAB70998.3| Hypothetical protein M01D1.2 [Caenorh...    45   0.011
gi|32564823|ref|NP_493891.2| Meprin/TRAF-like MATH family member...    45   0.011
gi|39580882|emb|CAE73880.1| Hypothetical protein CBG21474 [Caeno...    45   0.011
gi|39579674|emb|CAE56506.1| Hypothetical protein CBG24226 [Caeno...    44   0.014
gi|17531223|ref|NP_494165.1| Meprin/TRAF-like MATH and BTB/POZ d...    44   0.014
gi|39591368|emb|CAE73422.1| Hypothetical protein CBG20865 [Caeno...    44   0.014
gi|39581256|emb|CAE60002.1| Hypothetical protein CBG03498 [Caeno...    44   0.018
gi|7507419|pir||T33378 hypothetical protein T07H3.6 - Caenorhabd...    43   0.031
gi|17533827|ref|NP_494288.1| Meprin/TRAF-like MATH and BTB/POZ d...    43   0.031
gi|34365959|gb|AAC26269.2| Hypothetical protein F40B1.2 [Caenorh...    43   0.041
gi|39580290|emb|CAE73077.1| Hypothetical protein CBG20453 [Caeno...    42   0.091
gi|39580285|emb|CAE73072.1| Hypothetical protein CBG20446 [Caeno...    42   0.091
gi|39585636|emb|CAE65396.1| Hypothetical protein CBG10347 [Caeno...    40   0.27
gi|17509469|ref|NP_493234.1| BTB/POZ domain and Meprin/TRAF-like...    40   0.27
gi|24641480|ref|NP_572779.2| CG1490-PB [Drosophila melanogaster]...    40   0.35
gi|21243848|ref|NP_643430.1| TonB-dependent receptor [Xanthomona...    39   0.45
gi|39579264|emb|CAE56961.1| Hypothetical protein CBG24811 [Caeno...    38   1.0
gi|33861895|ref|NP_893456.1| SAICAR synthetase [Prochlorococcus ...    38   1.3
gi|39580862|emb|CAE73123.1| Hypothetical protein CBG20505 [Caeno...    38   1.3
gi|39579985|emb|CAE74198.1| Hypothetical protein CBG21875 [Caeno...    38   1.3
gi|21232375|ref|NP_638292.1| TonB-dependent receptor [Xanthomona...    38   1.3
gi|39596118|emb|CAE69754.1| Hypothetical protein CBG16034 [Caeno...    37   1.7
gi|17534615|ref|NP_494160.1| Meprin/TRAF-like MATH and BTB/POZ d...    37   2.3
gi|38176019|gb|AAF39861.2| Hypothetical protein F59H6.1 [Caenorh...    37   2.3
gi|39588987|emb|CAE69617.1| Hypothetical protein CBG15851 [Caeno...    37   2.9
gi|39596117|emb|CAE69753.1| Hypothetical protein CBG16033 [Caeno...    36   5.0
gi|39580968|emb|CAE72938.1| Hypothetical protein CBG20266 [Caeno...    35   6.5
gi|17531219|ref|NP_494163.1| Meprin/TRAF-like MATH and BTB/POZ d...    35   8.6
gi|32564766|ref|NP_871999.1| cyclin-like F-box and BTB/POZ domai...    35   8.6
gi|50727061|gb|AAT81201.1| Hypothetical protein F14D2.15 [Caenor...    35   8.6
gi|32699265|gb|AAB66045.2| Hypothetical protein B0047.5 [Caenorh...    35   8.6
gi|11061654|emb|CAC14530.1| possible vacuolar sorting protein [L...    35   8.6


>gi|17533755|ref|NP_494075.1| Meprin/TRAF-like MATH family member
            (96.2 kD) (2C63) [Caenorhabditis elegans]
 gi|13592423|gb|AAK31520.1| Hypothetical protein F36H5.1
            [Caenorhabditis elegans]
          Length = 821

 Score = 1660 bits (4300), Expect = 0.0
 Identities = 807/821 (98%), Positives = 807/821 (98%)
 Frame = +1

Query: 1    MSLSKCEFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSN 180
            MSLSKCEFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSN
Sbjct: 1    MSLSKCEFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSN 60

Query: 181  TWIKDCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLT 360
            TWIKDCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLT
Sbjct: 61   TWIKDCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLT 120

Query: 361  ADSVKIVVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVK 540
            ADSVKIVVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVK
Sbjct: 121  ADSVKIVVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVK 180

Query: 541  KEEGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMK 720
            KEEGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMK
Sbjct: 181  KEEGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMK 240

Query: 721  WEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFE 900
            WEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFE
Sbjct: 241  WEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFE 300

Query: 901  KRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFC 1080
            KRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFC
Sbjct: 301  KRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFC 360

Query: 1081 RDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVF 1260
            RDVDMESLKKSLKKVIRWDDMMTDYVINDSF              ACFWPYWITEEDAVF
Sbjct: 361  RDVDMESLKKSLKKVIRWDDMMTDYVINDSFIIEAHIEILSIIEEACFWPYWITEEDAVF 420

Query: 1261 HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLD 1440
            HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLD
Sbjct: 421  HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLD 480

Query: 1441 QLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEA 1620
            QLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEA
Sbjct: 481  QLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEA 540

Query: 1621 HVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYING 1800
            HVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYING
Sbjct: 541  HVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYING 600

Query: 1801 FVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWED 1980
            FVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWED
Sbjct: 601  FVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWED 660

Query: 1981 MLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREGEFHFSKTETHCDAP 2160
            MLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREGEFHFSKTETHCDAP
Sbjct: 661  MLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREGEFHFSKTETHCDAP 720

Query: 2161 WRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGI 2340
            WRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGI
Sbjct: 721  WRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGI 780

Query: 2341 HWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 2463
            HWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH
Sbjct: 781  HWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 821


>gi|7500678|pir||T25744 hypothetical protein F36H5.1 - Caenorhabditis
            elegans
          Length = 714

 Score = 1426 bits (3691), Expect = 0.0
 Identities = 702/730 (96%), Positives = 702/730 (96%)
 Frame = +1

Query: 274  MKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKIVVIVNNFTALEDIDFLCGFKILHTF 453
            MKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKIVVIVNNFTALEDIDFLCGFKILHTF
Sbjct: 1    MKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKIVVIVNNFTALEDIDFLCGFKILHTF 60

Query: 454  KHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLICVSAICELRI 633
            KHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLICVSAICELRI
Sbjct: 61   KHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLICVSAICELRI 120

Query: 634  KSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKND 813
            KSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKND
Sbjct: 121  KSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKND 180

Query: 814  YMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFL 993
            YMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFL
Sbjct: 181  YMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFL 240

Query: 994  YHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSF 1173
            YHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSF
Sbjct: 241  YHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSF 300

Query: 1174 XXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRY 1353
                                 I EE      RSFYISCKVNNVSRFLDDEKQWGNTELRY
Sbjct: 301  IIEAHIEILS-----------IIEE-----ARSFYISCKVNNVSRFLDDEKQWGNTELRY 344

Query: 1354 EIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPG 1533
            EIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPG
Sbjct: 345  EIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPG 404

Query: 1534 GQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVS 1713
            GQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVS
Sbjct: 405  GQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVS 464

Query: 1714 SAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGA 1893
            SAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGA
Sbjct: 465  SAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGA 524

Query: 1894 NGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSF 2073
            NGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSF
Sbjct: 525  NGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSF 584

Query: 2074 IMCHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQ 2253
            IMCHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQ
Sbjct: 585  IMCHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQ 644

Query: 2254 VEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVK 2433
            VEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVK
Sbjct: 645  VEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVK 704

Query: 2434 PVEIDNEDEH 2463
            PVEIDNEDEH
Sbjct: 705  PVEIDNEDEH 714



 Score =  295 bits (754), Expect = 5e-78
 Identities = 206/692 (29%), Positives = 327/692 (46%), Gaps = 13/692 (1%)
 Frame = +1

Query: 16   CEFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKD 195
            C F + +T K++++F   E QFSD   W    W++ + K + +LG  + C    NT +
Sbjct: 52   CGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSL-- 109

Query: 196  CQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVK 375
              +  I E +I S        + +L    P      M+   + +KW+++  N+L +DSV
Sbjct: 110  ICVSAICELRIKSKENYEIFDLDVLEFSRP-----TMLGNSKLMKWEDLISNYLVSDSVT 164

Query: 376  I---VVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKE 546
            I   +   N F    D      F +   F  ++R EE E++FS  ++     WRI +K+
Sbjct: 165  IEADLEAYNEFPVKNDY-MAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRV 223

Query: 547  EGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGN-----SK 711
             G+L  +L C  N       +   C   + S     +       F R   + +      K
Sbjct: 224  SGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKK 283

Query: 712  LMKWEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFS 891
            +++W+D++++Y+++DS  IEA +E  +         A+ F +S +  +VSR  + E ++
Sbjct: 284  VIRWDDMMTDYVINDSFIIEAHIEILSIIE-----EARSFYISCKVNNVSRFLDDEKQWG 338

Query: 892  AFEKRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSA 1071
              E R+ IPWRI+ KR   FLE++L C      L   I+T+   NLVSTNG +  R
Sbjct: 339  NTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKL 398

Query: 1072 VFCRDVDMESLKKSLKKVIRWDDMMTDYV--INDSFXXXXXXXXXXXXXXACFWPYWITE 1245
             F +        + + K I+W+DM+  ++  + DS                    + + E
Sbjct: 399  CFEKPGG-----QGIIKFIKWNDMIESFLNPLEDSLIVEAHVKI-----------FMVEE 442

Query: 1246 EDAVF--HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCD 1419
                F  +ERSF +S  V +VS   +    +  TE  Y++ W I  K    F+E+ L CD
Sbjct: 443  FSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCD 502

Query: 1420 GEGNGLDQ-LIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPL 1596
             + N  +   I+T     LV  NG       +  FEKP   G  K I+W DM++ +   +
Sbjct: 503  KDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQY--AV 560

Query: 1597 EDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWS 1776
            EDSL VEA V   ++ E      Q E SF+M HTV+ +S+  EG   FS TE   D  W
Sbjct: 561  EDSLTVEARVNFTLLIE-----PQPEYSFIMCHTVKKLSNVREGEFHFSKTETHCDAPWR 615

Query: 1777 ISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGD 1956
            IS+K     + + L CDK L+  E WSI+   QL+L    G+ LTD   H F +P+ I
Sbjct: 616  ISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHW 675

Query: 1957 SKLIRWEDMLDQYAVEDSLTVEARVNFTLLIE 2052
            +K + WED+   + V+DS+ +EARV     +E
Sbjct: 676  TKDLTWEDLERDFMVDDSVKIEARVKIVKPVE 707


>gi|7500679|pir||T25743 hypothetical protein F36H5.2 - Caenorhabditis
            elegans
          Length = 686

 Score = 1182 bits (3059), Expect(2) = 0.0
 Identities = 595/693 (85%), Positives = 614/693 (87%), Gaps = 1/693 (0%)
 Frame = +1

Query: 388  VNNFTALEDIDFLCG-FKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGC 564
            V+NF   E   FL G F+I H  KHL RFEE ETQFSD KE  G  WRICV KEE YL C
Sbjct: 14   VDNFATTEHPSFLSGEFEISHQLKHLERFEEYETQFSDVKECQGILWRICVIKEERYLEC 73

Query: 565  YLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNY 744
            YLQCESNPNTSLICVSAIC+LRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNY
Sbjct: 74   YLQCESNPNTSLICVSAICKLRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNY 133

Query: 745  LVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWR 924
            LVSDSVTIEADLEAYN  PV+ +YM KKFVLS QF DVS IE  E RFS FEKRFNIPWR
Sbjct: 134  LVSDSVTIEADLEAYNGCPVRENYMTKKFVLSHQFSDVSCIEIRERRFSKFEKRFNIPWR 193

Query: 925  IELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESL 1104
            IELKRVSGFLEIHLHCGENATF YH+IETDCWFNLVSTNGKHLMRQMSA F R  D+
Sbjct: 194  IELKRVSGFLEIHLHCGENATFDYHKIETDCWFNLVSTNGKHLMRQMSAKFYRISDI--- 250

Query: 1105 KKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYIS 1284
             KSL+KVIRWDDMMTD+VINDSF                     I EE      RSFYIS
Sbjct: 251  -KSLRKVIRWDDMMTDFVINDSFIIEAHIEILS-----------IIEE-----ARSFYIS 293

Query: 1285 CKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVT 1464
            CKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVT
Sbjct: 294  CKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVT 353

Query: 1465 CNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVE 1644
            CNLVSTNGNNFRRT++L F+KPGGQ I +FIKWNDMIESFLNPLEDSLIVEAHVKIFMVE
Sbjct: 354  CNLVSTNGNNFRRTTELNFKKPGGQSISEFIKWNDMIESFLNPLEDSLIVEAHVKIFMVE 413

Query: 1645 EFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSC 1824
            EFSR+FLQNERSFLMSHTVRDVSSAEEGNVVF ATEEWYDVQWSISMKYINGFVELLLSC
Sbjct: 414  EFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWYDVQWSISMKYINGFVELLLSC 473

Query: 1825 DKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVE 2004
            DKDLNAHEAWSIE + Q ILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVE
Sbjct: 474  DKDLNAHEAWSIEASVQRILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVE 533

Query: 2005 DSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKE 2184
            DSLTVEARV +T +I+PQPEYSFIMCHTVKKLSNVREGEFHFSKTE HCDAPWRISLKKE
Sbjct: 534  DSLTVEARVVYTKIIDPQPEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLKKE 593

Query: 2185 EACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTW 2364
            EACILIYLHCDKLLSNDE+WSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTW
Sbjct: 594  EACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTW 653

Query: 2365 EDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 2463
            EDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH
Sbjct: 654  EDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 686



 Score =  279 bits (714), Expect = 2e-73
 Identities = 198/688 (28%), Positives = 330/688 (47%), Gaps = 10/688 (1%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKDC 198
            EF + + +K++ +F   E QFSD    + ++W++ + K + +L   + C    NT +
Sbjct: 29   EFEISHQLKHLERFEEYETQFSDVKECQGILWRICVIKEERYLECYLQCESNPNTSLICV 88

Query: 199  QIVGILECKIVSDNGETHE--GIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSV 372
              +    CK+   + E +E   + +L    P      M+   + +KW+++  N+L +DSV
Sbjct: 89   SAI----CKLRIKSKENYEIFDLDVLEFSRP-----TMLGNSKLMKWEDLISNYLVSDSV 139

Query: 373  KIVVIVN--NFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKE 546
             I   +   N   + +      F + H F  ++  E  E +FS  ++     WRI +K+
Sbjct: 140  TIEADLEAYNGCPVRENYMTKKFVLSHQFSDVSCIEIRERRFSKFEKRFNIPWRIELKRV 199

Query: 547  EGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGN-SKLMKW 723
             G+L  +L C  N       +   C   + S     +      +F R + + +  K+++W
Sbjct: 200  SGFLEIHLHCGENATFDYHKIETDCWFNLVSTNGKHLMRQMSAKFYRISDIKSLRKVIRW 259

Query: 724  EDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEK 903
            +D++++++++DS  IEA +E  +         A+ F +S +  +VSR  + E ++   E
Sbjct: 260  DDMMTDFVINDSFIIEAHIEILSIIE-----EARSFYISCKVNNVSRFLDDEKQWGNTEL 314

Query: 904  RFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCR 1083
            R+ IPWRI+ KR   FLE++L C      L   I+T+   NLVSTNG +  R     F +
Sbjct: 315  RYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTTELNFKK 374

Query: 1084 DVDMESLKKSLKKVIRWDDMMTDYV--INDSFXXXXXXXXXXXXXXACFWPYWITEEDAV 1257
                    +S+ + I+W+DM+  ++  + DS                    + + E
Sbjct: 375  PGG-----QSISEFIKWNDMIESFLNPLEDSLIVEAHVKI-----------FMVEEFSRK 418

Query: 1258 F--HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGN 1431
            F  +ERSF +S  V +VS   +    +  TE  Y++ W I  K    F+E+ L CD + N
Sbjct: 419  FLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWYDVQWSISMKYINGFVELLLSCDKDLN 478

Query: 1432 GLDQ-LIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSL 1608
              +   I+  V   LV  NG       +  FEKP   G  K I+W DM++ +   +EDSL
Sbjct: 479  AHEAWSIEASVQRILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQY--AVEDSL 536

Query: 1609 IVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMK 1788
             VEA V    + +      Q E SF+M HTV+ +S+  EG   FS TE+  D  W IS+K
Sbjct: 537  TVEARVVYTKIID-----PQPEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLK 591

Query: 1789 YINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLI 1968
                 + + L CDK L+  E WSI+   QL+L    G+ LTD   H F +P+ I  +K +
Sbjct: 592  KEEACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDL 651

Query: 1969 RWEDMLDQYAVEDSLTVEARVNFTLLIE 2052
             WED+   + V+DS+ +EARV     +E
Sbjct: 652  TWEDLERDFMVDDSVKIEARVKIVKPVE 679



 Score = 25.4 bits (54), Expect(2) = 0.0
 Identities = 11/21 (52%), Positives = 14/21 (66%)
 Frame = +3

Query: 330 MGRNEKKLFDCG*CQNCSYCE 392
           MGR+ K+LFDCG   N +  E
Sbjct: 1   MGRDGKQLFDCGCVDNFATTE 21


>gi|32564805|ref|NP_872003.1| Meprin/TRAF-like MATH family member
            (2C59) [Caenorhabditis elegans]
 gi|22532918|gb|AAM98020.1| Hypothetical protein F36H5.2b
            [Caenorhabditis elegans]
          Length = 570

 Score = 1031 bits (2667), Expect = 0.0
 Identities = 516/590 (87%), Positives = 532/590 (89%)
 Frame = +1

Query: 694  MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEE 873
            MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYN  PV+ +YM KKFVLS QF DVS IE
Sbjct: 1    MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNGCPVRENYMTKKFVLSHQFSDVSCIEI 60

Query: 874  GESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETDCWFNLVSTNGKHL 1053
             E RFS FEKRFNIPWRIELKRVSGFLEIHLHCGENATF YH+IETDCWFNLVSTNGKHL
Sbjct: 61   RERRFSKFEKRFNIPWRIELKRVSGFLEIHLHCGENATFDYHKIETDCWFNLVSTNGKHL 120

Query: 1054 MRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPY 1233
            MRQMSA F R  D+    KSL+KVIRWDDMMTD+VINDSF
Sbjct: 121  MRQMSAKFYRISDI----KSLRKVIRWDDMMTDFVINDSFIIEAHIEILS---------- 166

Query: 1234 WITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLF 1413
             I EE      RSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLF
Sbjct: 167  -IIEE-----ARSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLF 220

Query: 1414 CDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNP 1593
            CDGEGNGLDQLIKTEVTCNLVSTNGNNFRRT++L F+KPGGQ I +FIKWNDMIESFLNP
Sbjct: 221  CDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTTELNFKKPGGQSISEFIKWNDMIESFLNP 280

Query: 1594 LEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQW 1773
            LEDSLIVEAHVKIFMVEEFSR+FLQNERSFLMSHTVRDVSSAEEGNVVF ATEEWYDVQW
Sbjct: 281  LEDSLIVEAHVKIFMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWYDVQW 340

Query: 1774 SISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIG 1953
            SISMKYINGFVELLLSCDKDLNAHEAWSIE + Q ILVGANGKRLTDYFEHTFEKPDSIG
Sbjct: 341  SISMKYINGFVELLLSCDKDLNAHEAWSIEASVQRILVGANGKRLTDYFEHTFEKPDSIG 400

Query: 1954 DSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREGEFHFS 2133
            DSKLIRWEDMLDQYAVEDSLTVEARV +T +I+PQPEYSFIMCHTVKKLSNVREGEFHFS
Sbjct: 401  DSKLIRWEDMLDQYAVEDSLTVEARVVYTKIIDPQPEYSFIMCHTVKKLSNVREGEFHFS 460

Query: 2134 KTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVT 2313
            KTE HCDAPWRISLKKEEACILIYLHCDKLLSNDE+WSIQVEVQLVLGSETGRTLTDKVT
Sbjct: 461  KTEQHCDAPWRISLKKEEACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVT 520

Query: 2314 HIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 2463
            HIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH
Sbjct: 521  HIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 570



 Score =  255 bits (651), Expect = 4e-66
 Identities = 176/591 (29%), Positives = 287/591 (47%), Gaps = 8/591 (1%)
 Frame = +1

Query: 304  MIDFREFLKWDEMKKNFLTADSVKIVVIVNNFTA--LEDIDFLCGFKILHTFKHLARFEE 477
            M+   + +KW+++  N+L +DSV I   +  +    + +      F + H F  ++  E
Sbjct: 1    MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNGCPVRENYMTKKFVLSHQFSDVSCIEI 60

Query: 478  NETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEI 657
             E +FS  ++     WRI +K+  G+L  +L C  N       +   C   + S     +
Sbjct: 61   RERRFSKFEKRFNIPWRIELKRVSGFLEIHLHCGENATFDYHKIETDCWFNLVSTNGKHL 120

Query: 658  FDLDVLEFSRPTMLGN-SKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFV 834
                  +F R + + +  K+++W+D++++++++DS  IEA +E  +         A+ F
Sbjct: 121  MRQMSAKFYRISDIKSLRKVIRWDDMMTDFVINDSFIIEAHIEILSIIE-----EARSFY 175

Query: 835  LSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIETD 1014
            +S +  +VSR  + E ++   E R+ IPWRI+ KR   FLE++L C      L   I+T+
Sbjct: 176  ISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQLIKTE 235

Query: 1015 CWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYV--INDSFXXXXX 1188
               NLVSTNG +  R     F +        +S+ + I+W+DM+  ++  + DS
Sbjct: 236  VTCNLVSTNGNNFRRTTELNFKKPGG-----QSISEFIKWNDMIESFLNPLEDSLIVEAH 290

Query: 1189 XXXXXXXXXACFWPYWITEEDAVF--HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIP 1362
                          + + E    F  +ERSF +S  V +VS   +    +  TE  Y++
Sbjct: 291  VKI-----------FMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWYDVQ 339

Query: 1363 WRIQAKRTYDFLEMYLFCDGEGNGLDQ-LIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQ 1539
            W I  K    F+E+ L CD + N  +   I+  V   LV  NG       +  FEKP
Sbjct: 340  WSISMKYINGFVELLLSCDKDLNAHEAWSIEASVQRILVGANGKRLTDYFEHTFEKPDSI 399

Query: 1540 GIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSA 1719
            G  K I+W DM++ +   +EDSL VEA V    + +      Q E SF+M HTV+ +S+
Sbjct: 400  GDSKLIRWEDMLDQY--AVEDSLTVEARVVYTKIID-----PQPEYSFIMCHTVKKLSNV 452

Query: 1720 EEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANG 1899
             EG   FS TE+  D  W IS+K     + + L CDK L+  E WSI+   QL+L    G
Sbjct: 453  REGEFHFSKTEQHCDAPWRISLKKEEACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETG 512

Query: 1900 KRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIE 2052
            + LTD   H F +P+ I  +K + WED+   + V+DS+ +EARV     +E
Sbjct: 513  RTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVE 563



 Score =  158 bits (399), Expect = 7e-37
 Identities = 147/547 (26%), Positives = 244/547 (43%), Gaps = 9/547 (1%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKDC 198
            +F + +   +VS     E +FS      N+ W++++ ++  FL + ++C +  N
Sbjct: 45   KFVLSHQFSDVSCIEIRERRFSKFEKRFNIPWRIELKRVSGFLEIHLHCGE--NATFDYH 102

Query: 199  QIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKI 378
            +I       +VS NG+    +R ++ K  R  +  +   R+ ++WD+M  +F+  DS
Sbjct: 103  KIETDCWFNLVSTNGK--HLMRQMSAKFYRISD--IKSLRKVIRWDDMMTDFVINDS--- 155

Query: 379  VVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGYL 558
             +I  +   L  I+    F I     +++RF ++E Q+ +++      WRI  K+   +L
Sbjct: 156  FIIEAHIEILSIIEEARSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFL 215

Query: 559  GCYLQC--ESNPNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDL 732
              YL C  E N    LI     C L   +  N+       L F +P     S+ +KW D+
Sbjct: 216  EMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFR--RTTELNFKKPGGQSISEFIKWNDM 273

Query: 733  ISNYL--VSDSVTIEADLEAY--NEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFE 900
            I ++L  + DS+ +EA ++ +   EF  K     + F++S    DVS  EEG   F A E
Sbjct: 274  IESFLNPLEDSLIVEAHVKIFMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATE 333

Query: 901  KRFNIPWRIELKRVSGFLEIHLHCGE--NATFLYHQIETDCWFNLVSTNGKHLMRQMSAV 1074
            + +++ W I +K ++GF+E+ L C +  NA   +  IE      LV  NGK L
Sbjct: 334  EWYDVQWSISMKYINGFVELLLSCDKDLNAHEAW-SIEASVQRILVGANGKRLTDYFEHT 392

Query: 1075 FCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDA 1254
            F +    +S+  S  K+IRW+DM+  Y + DS                       T+
Sbjct: 393  FEKP---DSIGDS--KLIRWEDMLDQYAVEDSLTVEARVV--------------YTKIID 433

Query: 1255 VFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDG-EGN 1431
               E SF +   V  +S   + E  +  TE   + PWRI  K+    + +YL CD    N
Sbjct: 434  PQPEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLKKEEACILIYLHCDKLLSN 493

Query: 1432 GLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLI 1611
                 I+ EV   L S  G          F +P G    K + W D+   F+  ++DS+
Sbjct: 494  DEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFM--VDDSVK 551

Query: 1612 VEAHVKI 1632
            +EA VKI
Sbjct: 552  IEARVKI 558



 Score =  142 bits (359), Expect = 3e-32
 Identities = 105/391 (26%), Positives = 181/391 (45%), Gaps = 8/391 (2%)
 Frame = +1

Query: 22   FSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKDCQ 201
            F +   + NVS+F   E Q+ +  +   + W+++  +  DFL + ++C    N    D
Sbjct: 174  FYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGL--DQL 231

Query: 202  IVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTA--DSVK 375
            I   + C +VS NG        LN K P    G  I   EF+KW++M ++FL    DS+
Sbjct: 232  IKTEVTCNLVSTNGNNFRRTTELNFKKPG---GQSIS--EFIKWNDMIESFLNPLEDSLI 286

Query: 376  IVVIVNNFTALE-DIDFLCG---FKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKK 543
            +   V  F   E    FL     F + HT + ++  EE    F  ++EW    W I +K
Sbjct: 287  VEAHVKIFMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWYDVQWSISMKY 346

Query: 544  EEGYLGCYLQCESNPNT-SLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMK 720
              G++   L C+ + N      + A  +  +       + D     F +P  +G+SKL++
Sbjct: 347  INGFVELLLSCDKDLNAHEAWSIEASVQRILVGANGKRLTDYFEHTFEKPDSIGDSKLIR 406

Query: 721  WEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFE 900
            WED++  Y V DS+T+EA +        + +Y    F++      +S + EGE  FS  E
Sbjct: 407  WEDMLDQYAVEDSLTVEARVVYTKIIDPQPEY---SFIMCHTVKKLSNVREGEFHFSKTE 463

Query: 901  KRFNIPWRIELKRVSGFLEIHLHCGENATFLYH-QIETDCWFNLVSTNGKHLMRQMSAVF 1077
            +  + PWRI LK+    + I+LHC +  +   H  I+ +    L S  G+ L  +++ +F
Sbjct: 464  QHCDAPWRISLKKEEACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVTHIF 523

Query: 1078 CRDVDMESLKKSLKKVIRWDDMMTDYVINDS 1170
                 +   K      + W+D+  D++++DS
Sbjct: 524  NEPEGIHWTKD-----LTWEDLERDFMVDDS 549



 Score = 87.4 bits (215), Expect = 1e-15
 Identities = 66/268 (24%), Positives = 120/268 (44%), Gaps = 4/268 (1%)
 Frame = +1

Query: 22   FSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNT---WIK 192
            F M +T+++VS    G + F     W ++ W + +  ++ F+ + + C +  N    W
Sbjct: 310  FLMSHTVRDVSSAEEGNVVFCATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSI 369

Query: 193  DCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSV 372
            +  +  IL    V  NG+     RL +       +   I   + ++W++M   +   DS+
Sbjct: 370  EASVQRIL----VGANGK-----RLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSL 420

Query: 373  KIVVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEG 552
             +   V  +T + D      F + HT K L+   E E  FS +++     WRI +KKEE
Sbjct: 421  TVEARVV-YTKIIDPQPEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLKKEEA 479

Query: 553  YLGCYLQCESN-PNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWED 729
             +  YL C+    N     +    +L + S+    + D     F+ P  +  +K + WED
Sbjct: 480  CILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWED 539

Query: 730  LISNYLVSDSVTIEADLEAYNEFPVKND 813
            L  +++V DSV IEA ++      + N+
Sbjct: 540  LERDFMVDDSVKIEARVKIVKPVEIDNE 567


>gi|17531653|ref|NP_494076.1| Meprin/TRAF-like MATH family member
            (2C67) [Caenorhabditis elegans]
 gi|13592308|gb|AAK31407.1| Hypothetical protein C08F1.4a
            [Caenorhabditis elegans]
          Length = 520

 Score =  819 bits (2116), Expect = 0.0
 Identities = 406/524 (77%), Positives = 443/524 (84%), Gaps = 5/524 (0%)
 Frame = +1

Query: 694  MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYN--EFPVKNDYMAKKFVLSQQFYDVSRI 867
            M G  KLMKWE L+SN+LV+DSVT+EADL  +N   + + +    KKFVLSQQF DVSRI
Sbjct: 1    MKGYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAGYKIFDKSTTKKFVLSQQFSDVSRI 60

Query: 868  EEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCG---ENATFLYHQIETDCWFNLVST 1038
            EEGESRFS FEKRFNIPWRIEL+RVSGFLEIHLH G   E    ++  I+ DCWFNLVST
Sbjct: 61   EEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKADCWFNLVST 120

Query: 1039 NGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXA 1218
            NGK+LMRQMSAVFCRDVDMESLKK    VIRWDDMMTDYVINDSF
Sbjct: 121  NGKNLMRQMSAVFCRDVDMESLKK----VIRWDDMMTDYVINDSFIIEAHIEILRIIEKK 176

Query: 1219 CFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFL 1398
             F P W++    VF+ER FYI+CKVNNVSRF D EKQWGNTELRY+IPWRIQ KR+ DFL
Sbjct: 177  NFSPNWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGNTELRYDIPWRIQTKRSLDFL 236

Query: 1399 EMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIE 1578
            E+YLFCD + N   +LI+T+ T NLVSTNGNN+RRTSKLCFEKPGGQGI  F KWNDMIE
Sbjct: 237  ELYLFCDEDDNVSKKLIQTKCTFNLVSTNGNNYRRTSKLCFEKPGGQGISGFFKWNDMIE 296

Query: 1579 SFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEW 1758
            SFLNPLEDSLIVEAHVKIFMVEEFSR+ LQNERSFLMSH VR+VS+  EG V+FSA++EW
Sbjct: 297  SFLNPLEDSLIVEAHVKIFMVEEFSRKILQNERSFLMSHVVRNVSNMVEGGVIFSASQEW 356

Query: 1759 YDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEK 1938
            YD+ WSISMKYINGFVELLLSCDK+LNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEK
Sbjct: 357  YDIPWSISMKYINGFVELLLSCDKELNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEK 416

Query: 1939 PDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREG 2118
            PDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNF +LIEPQPEYSFIM HTVK LSNV EG
Sbjct: 417  PDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFIMLIEPQPEYSFIMSHTVKNLSNVHEG 476

Query: 2119 EFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSI 2250
            EFHFSKTE HCDAPWRISLKKEE C+LIYLHCDKLLSNDE+WS+
Sbjct: 477  EFHFSKTEKHCDAPWRISLKKEEMCLLIYLHCDKLLSNDEHWSV 520



 Score =  233 bits (594), Expect = 2e-59
 Identities = 153/465 (32%), Positives = 239/465 (50%), Gaps = 20/465 (4%)
 Frame = +1

Query: 1108 KSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISC 1287
            K  +K+++W+ +++++++NDS                    Y I ++      + F +S
Sbjct: 2    KGYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAG------YKIFDKSTT---KKFVLSQ 52

Query: 1288 KVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQ---LIKTE 1458
            + ++VSR  + E ++   E R+ IPWRI+ +R   FLE++L    E    D    +IK +
Sbjct: 53   QFSDVSRIEEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKAD 112

Query: 1459 VTCNLVSTNGNNFRRTSKLCFEKPGG-QGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIF 1635
               NLVSTNG N  R     F +    + + K I+W+DM+  ++  + DS I+EAH++I
Sbjct: 113  CWFNLVSTNGKNLMRQMSAVFCRDVDMESLKKVIRWDDMMTDYV--INDSFIIEAHIEIL 170

Query: 1636 MVEE---FSRRFLQN------ERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMK 1788
             + E   FS  +L        ER F ++  V +VS  ++G   +  TE  YD+ W I  K
Sbjct: 171  RIIEKKNFSPNWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGNTELRYDIPWRIQTK 230

Query: 1789 YINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLI 1968
                F+EL L CD+D N  +   I+T     LV  NG       +  FEKP   G S
Sbjct: 231  RSLDFLELYLFCDEDDNVSKKL-IQTKCTFNLVSTNGNNYRRTSKLCFEKPGGQGISGFF 289

Query: 1969 RWEDMLDQYA--VEDSLTVEARVNFTLLIE-----PQPEYSFIMCHTVKKLSNVREGEFH 2127
            +W DM++ +   +EDSL VEA V   ++ E      Q E SF+M H V+ +SN+ EG
Sbjct: 290  KWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRKILQNERSFLMSHVVRNVSNMVEGGVI 349

Query: 2128 FSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDK 2307
            FS ++   D PW IS+K     + + L CDK L+  E WSI+   QL+L    G+ LTD
Sbjct: 350  FSASQEWYDIPWSISMKYINGFVELLLSCDKELNAHEAWSIETNFQLILVGANGKRLTDY 409

Query: 2308 VTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVE 2442
              H F +P+ I  +K + WED+   + V+DS+ +EARV  +  +E
Sbjct: 410  FEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFIMLIE 454



 Score =  226 bits (577), Expect = 2e-57
 Identities = 163/541 (30%), Positives = 258/541 (47%), Gaps = 22/541 (4%)
 Frame = +1

Query: 304  MIDFREFLKWDEMKKNFLTADSVKIVVIVNNFT----ALEDIDFLCGFKILHTFKHLARF 471
            M  +R+ +KW+++  N L  DSV +   +N F      + D      F +   F  ++R
Sbjct: 1    MKGYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAGYKIFDKSTTKKFVLSQQFSDVSRI 60

Query: 472  EENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCE---SNPNTSLICVSAICELRIKSK 642
            EE E++FS  ++     WRI +++  G+L  +L        P+     + A C   + S
Sbjct: 61   EEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKADCWFNLVST 120

Query: 643  ENYEIFDLDVLEFSRPT-MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKN--- 810
                +       F R   M    K+++W+D++++Y+++DS  IEA +E       KN
Sbjct: 121  NGKNLMRQMSAVFCRDVDMESLKKVIRWDDMMTDYVINDSFIIEAHIEILRIIEKKNFSP 180

Query: 811  ---DYM-----AKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHL 966
                YM      + F ++ +  +VSR ++GE ++   E R++IPWRI+ KR   FLE++L
Sbjct: 181  NWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGNTELRYDIPWRIQTKRSLDFLELYL 240

Query: 967  HCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMM 1146
             C E+       I+T C FNLVSTNG +  R     F +        + +    +W+DM+
Sbjct: 241  FCDEDDNVSKKLIQTKCTFNLVSTNGNNYRRTSKLCFEKPGG-----QGISGFFKWNDMI 295

Query: 1147 TDYV--INDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDD 1320
              ++  + DS               +            + +ERSF +S  V NVS  ++
Sbjct: 296  ESFLNPLEDSLIVEAHVKIFMVEEFS---------RKILQNERSFLMSHVVRNVSNMVEG 346

Query: 1321 EKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQ-LIKTEVTCNLVSTNGNNF 1497
               +  ++  Y+IPW I  K    F+E+ L CD E N  +   I+T     LV  NG
Sbjct: 347  GVIFSASQEWYDIPWSISMKYINGFVELLLSCDKELNAHEAWSIETNFQLILVGANGKRL 406

Query: 1498 RRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNER 1677
                +  FEKP   G  K I+W DM++ +   +EDSL VEA V   M+ E      Q E
Sbjct: 407  TDYFEHTFEKPDSIGDSKLIRWEDMLDQY--AVEDSLTVEARVNFIMLIE-----PQPEY 459

Query: 1678 SFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWS 1857
            SF+MSHTV+++S+  EG   FS TE+  D  W IS+K     + + L CDK L+  E WS
Sbjct: 460  SFIMSHTVKNLSNVHEGEFHFSKTEKHCDAPWRISLKKEEMCLLIYLHCDKLLSNDEHWS 519

Query: 1858 I 1860
            +
Sbjct: 520  V 520



 Score =  148 bits (373), Expect = 7e-34
 Identities = 131/493 (26%), Positives = 226/493 (45%), Gaps = 26/493 (5%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFL------GVSVYCSQTSN 180
            +F +     +VS+   GE +FS      N+ W++++ ++  FL      G+ +
Sbjct: 47   KFVLSQQFSDVSRIEEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVF 106

Query: 181  TWIK-DCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFL 357
            T IK DC         +VS NG+    +R ++    R ++  M   ++ ++WD+M  +++
Sbjct: 107  TIIKADCWF------NLVSTNGKNL--MRQMSAVFCRDVD--MESLKKVIRWDDMMTDYV 156

Query: 358  TADS------VKIVVIVN--NFTA-----LEDIDFLCGFKILHTFKHLARFEENETQFSD 498
              DS      ++I+ I+   NF+      ++ + +   F I     +++RF++ E Q+ +
Sbjct: 157  INDSFIIEAHIEILRIIEKKNFSPNWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGN 216

Query: 499  SKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLE 678
            ++      WRI  K+   +L  YL C+ + N S   +   C   + S           L
Sbjct: 217  TELRYDIPWRIQTKRSLDFLELYLFCDEDDNVSKKLIQTKCTFNLVSTNGNNYRRTSKLC 276

Query: 679  FSRPTMLGNSKLMKWEDLISNYL--VSDSVTIEADLEAY--NEFPVKNDYMAKKFVLSQQ 846
            F +P   G S   KW D+I ++L  + DS+ +EA ++ +   EF  K     + F++S
Sbjct: 277  FEKPGGQGISGFFKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRKILQNERSFLMSHV 336

Query: 847  FYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGE--NATFLYHQIETDCW 1020
              +VS + EG   FSA ++ ++IPW I +K ++GF+E+ L C +  NA   +  IET+
Sbjct: 337  VRNVSNMVEGGVIFSASQEWYDIPWSISMKYINGFVELLLSCDKELNAHEAW-SIETNFQ 395

Query: 1021 FNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXX 1200
              LV  NGK L       F +    +S+  S  K+IRW+DM+  Y + DS
Sbjct: 396  LILVGANGKRLTDYFEHTFEKP---DSIGDS--KLIRWEDMLDQYAVEDSLTVEARVNF- 449

Query: 1201 XXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAK 1380
                        + E      E SF +S  V N+S   + E  +  TE   + PWRI  K
Sbjct: 450  ----------IMLIEPQP---EYSFIMSHTVKNLSNVHEGEFHFSKTEKHCDAPWRISLK 496

Query: 1381 RTYDFLEMYLFCD 1419
            +    L +YL CD
Sbjct: 497  KEEMCLLIYLHCD 509



 Score = 79.3 bits (194), Expect = 4e-13
 Identities = 49/175 (28%), Positives = 91/175 (52%), Gaps = 8/175 (4%)
 Frame = +1

Query: 1951 GDSKLIRWEDMLDQYAVEDSLTVEARVN-FTL----LIEPQPEYSFIMCHTVKKLSNVRE 2115
            G  KL++WE ++  + V DS+TVEA +N F L    + +      F++      +S + E
Sbjct: 3    GYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAGYKIFDKSTTKKFVLSQQFSDVSRIEE 62

Query: 2116 GEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDEN--WSIQVEVQLVLGSETG 2289
            GE  FS+ E   + PWRI L++    + I+LH    +   ++    I+ +    L S  G
Sbjct: 63   GESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKADCWFNLVSTNG 122

Query: 2290 RTLTDKVTHIFNEPEGIHWTKD-LTWEDLERDFMVDDSVKIEARVKIVKPVEIDN 2451
            + L  +++ +F     +   K  + W+D+  D++++DS  IEA ++I++ +E  N
Sbjct: 123  KNLMRQMSAVFCRDVDMESLKKVIRWDDMMTDYVINDSFIIEAHIEILRIIEKKN 177


>gi|7495680|pir||T32337 hypothetical protein C08F1.4 - Caenorhabditis
            elegans
          Length = 499

 Score =  765 bits (1976), Expect = 0.0
 Identities = 381/497 (76%), Positives = 416/497 (83%), Gaps = 5/497 (1%)
 Frame = +1

Query: 694  MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYN--EFPVKNDYMAKKFVLSQQFYDVSRI 867
            M G  KLMKWE L+SN+LV+DSVT+EADL  +N   + + +    KKFVLSQQF DVSRI
Sbjct: 1    MKGYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAGYKIFDKSTTKKFVLSQQFSDVSRI 60

Query: 868  EEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCG---ENATFLYHQIETDCWFNLVST 1038
            EEGESRFS FEKRFNIPWRIEL+RVSGFLEIHLH G   E    ++  I+ DCWFNLVST
Sbjct: 61   EEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKADCWFNLVST 120

Query: 1039 NGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXA 1218
            NGK+LMRQMSAVFCRDVDMESLKK    VIRWDDMMTDYVINDSF
Sbjct: 121  NGKNLMRQMSAVFCRDVDMESLKK----VIRWDDMMTDYVINDSFIIEAHIEILRIIEKK 176

Query: 1219 CFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFL 1398
             F P W++    VF+ER FYI+CKVNNVSRF D EKQWGNTELRY+IPWRIQ KR+ DFL
Sbjct: 177  NFSPNWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGNTELRYDIPWRIQTKRSLDFL 236

Query: 1399 EMYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIE 1578
            E+YLFCD + N   +LI+T+ T NLVSTNGNN+RRTSKLCFEKPGGQGI  F KWNDMIE
Sbjct: 237  ELYLFCDEDDNVSKKLIQTKCTFNLVSTNGNNYRRTSKLCFEKPGGQGISGFFKWNDMIE 296

Query: 1579 SFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEW 1758
            SFLNPLEDSLIVEAHVKIFMVEEFSR+ LQNERSFLMSH VR+VS+  EG V+FSA++EW
Sbjct: 297  SFLNPLEDSLIVEAHVKIFMVEEFSRKILQNERSFLMSHVVRNVSNMVEGGVIFSASQEW 356

Query: 1759 YDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEK 1938
            YD+ WSISMKYINGFVELLLSCDK+LNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEK
Sbjct: 357  YDIPWSISMKYINGFVELLLSCDKELNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEK 416

Query: 1939 PDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREG 2118
            PDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNF +LIEPQPEYSFIM HTVK LSNV EG
Sbjct: 417  PDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFIMLIEPQPEYSFIMSHTVKNLSNVHEG 476

Query: 2119 EFHFSKTETHCDAPWRI 2169
            EFHFSKTE HCDAPW +
Sbjct: 477  EFHFSKTEKHCDAPWSV 493



 Score =  233 bits (594), Expect = 2e-59
 Identities = 153/465 (32%), Positives = 239/465 (50%), Gaps = 20/465 (4%)
 Frame = +1

Query: 1108 KSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISC 1287
            K  +K+++W+ +++++++NDS                    Y I ++      + F +S
Sbjct: 2    KGYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAG------YKIFDKSTT---KKFVLSQ 52

Query: 1288 KVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQ---LIKTE 1458
            + ++VSR  + E ++   E R+ IPWRI+ +R   FLE++L    E    D    +IK +
Sbjct: 53   QFSDVSRIEEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKAD 112

Query: 1459 VTCNLVSTNGNNFRRTSKLCFEKPGG-QGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIF 1635
               NLVSTNG N  R     F +    + + K I+W+DM+  ++  + DS I+EAH++I
Sbjct: 113  CWFNLVSTNGKNLMRQMSAVFCRDVDMESLKKVIRWDDMMTDYV--INDSFIIEAHIEIL 170

Query: 1636 MVEE---FSRRFLQN------ERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMK 1788
             + E   FS  +L        ER F ++  V +VS  ++G   +  TE  YD+ W I  K
Sbjct: 171  RIIEKKNFSPNWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGNTELRYDIPWRIQTK 230

Query: 1789 YINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLI 1968
                F+EL L CD+D N  +   I+T     LV  NG       +  FEKP   G S
Sbjct: 231  RSLDFLELYLFCDEDDNVSKKL-IQTKCTFNLVSTNGNNYRRTSKLCFEKPGGQGISGFF 289

Query: 1969 RWEDMLDQYA--VEDSLTVEARVNFTLLIE-----PQPEYSFIMCHTVKKLSNVREGEFH 2127
            +W DM++ +   +EDSL VEA V   ++ E      Q E SF+M H V+ +SN+ EG
Sbjct: 290  KWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRKILQNERSFLMSHVVRNVSNMVEGGVI 349

Query: 2128 FSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDK 2307
            FS ++   D PW IS+K     + + L CDK L+  E WSI+   QL+L    G+ LTD
Sbjct: 350  FSASQEWYDIPWSISMKYINGFVELLLSCDKELNAHEAWSIETNFQLILVGANGKRLTDY 409

Query: 2308 VTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVE 2442
              H F +P+ I  +K + WED+   + V+DS+ +EARV  +  +E
Sbjct: 410  FEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFIMLIE 454



 Score =  212 bits (539), Expect = 4e-53
 Identities = 153/514 (29%), Positives = 244/514 (46%), Gaps = 22/514 (4%)
 Frame = +1

Query: 304  MIDFREFLKWDEMKKNFLTADSVKIVVIVNNFT----ALEDIDFLCGFKILHTFKHLARF 471
            M  +R+ +KW+++  N L  DSV +   +N F      + D      F +   F  ++R
Sbjct: 1    MKGYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAGYKIFDKSTTKKFVLSQQFSDVSRI 60

Query: 472  EENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCE---SNPNTSLICVSAICELRIKSK 642
            EE E++FS  ++     WRI +++  G+L  +L        P+     + A C   + S
Sbjct: 61   EEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKADCWFNLVST 120

Query: 643  ENYEIFDLDVLEFSRPT-MLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKN--- 810
                +       F R   M    K+++W+D++++Y+++DS  IEA +E       KN
Sbjct: 121  NGKNLMRQMSAVFCRDVDMESLKKVIRWDDMMTDYVINDSFIIEAHIEILRIIEKKNFSP 180

Query: 811  ---DYM-----AKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHL 966
                YM      + F ++ +  +VSR ++GE ++   E R++IPWRI+ KR   FLE++L
Sbjct: 181  NWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGNTELRYDIPWRIQTKRSLDFLELYL 240

Query: 967  HCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMM 1146
             C E+       I+T C FNLVSTNG +  R     F +        + +    +W+DM+
Sbjct: 241  FCDEDDNVSKKLIQTKCTFNLVSTNGNNYRRTSKLCFEKPGG-----QGISGFFKWNDMI 295

Query: 1147 TDYV--INDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDD 1320
              ++  + DS               +            + +ERSF +S  V NVS  ++
Sbjct: 296  ESFLNPLEDSLIVEAHVKIFMVEEFS---------RKILQNERSFLMSHVVRNVSNMVEG 346

Query: 1321 EKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQ-LIKTEVTCNLVSTNGNNF 1497
               +  ++  Y+IPW I  K    F+E+ L CD E N  +   I+T     LV  NG
Sbjct: 347  GVIFSASQEWYDIPWSISMKYINGFVELLLSCDKELNAHEAWSIETNFQLILVGANGKRL 406

Query: 1498 RRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNER 1677
                +  FEKP   G  K I+W DM++ +   +EDSL VEA V   M+ E      Q E
Sbjct: 407  TDYFEHTFEKPDSIGDSKLIRWEDMLDQY--AVEDSLTVEARVNFIMLIE-----PQPEY 459

Query: 1678 SFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSI 1779
            SF+MSHTV+++S+  EG   FS TE+  D  WS+
Sbjct: 460  SFIMSHTVKNLSNVHEGEFHFSKTEKHCDAPWSV 493



 Score =  135 bits (341), Expect = 4e-30
 Identities = 123/477 (25%), Positives = 217/477 (44%), Gaps = 26/477 (5%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFL------GVSVYCSQTSN 180
            +F +     +VS+   GE +FS      N+ W++++ ++  FL      G+ +
Sbjct: 47   KFVLSQQFSDVSRIEEGESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVF 106

Query: 181  TWIK-DCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFL 357
            T IK DC         +VS NG+    +R ++    R ++  M   ++ ++WD+M  +++
Sbjct: 107  TIIKADCWF------NLVSTNGKNL--MRQMSAVFCRDVD--MESLKKVIRWDDMMTDYV 156

Query: 358  TADS------VKIVVIVN--NFTA-----LEDIDFLCGFKILHTFKHLARFEENETQFSD 498
              DS      ++I+ I+   NF+      ++ + +   F I     +++RF++ E Q+ +
Sbjct: 157  INDSFIIEAHIEILRIIEKKNFSPNWLSYMKPVFYERCFYITCKVNNVSRFQDGEKQWGN 216

Query: 499  SKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLICVSAICELRIKSKENYEIFDLDVLE 678
            ++      WRI  K+   +L  YL C+ + N S   +   C   + S           L
Sbjct: 217  TELRYDIPWRIQTKRSLDFLELYLFCDEDDNVSKKLIQTKCTFNLVSTNGNNYRRTSKLC 276

Query: 679  FSRPTMLGNSKLMKWEDLISNYL--VSDSVTIEADLEAY--NEFPVKNDYMAKKFVLSQQ 846
            F +P   G S   KW D+I ++L  + DS+ +EA ++ +   EF  K     + F++S
Sbjct: 277  FEKPGGQGISGFFKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRKILQNERSFLMSHV 336

Query: 847  FYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGE--NATFLYHQIETDCW 1020
              +VS + EG   FSA ++ ++IPW I +K ++GF+E+ L C +  NA   +  IET+
Sbjct: 337  VRNVSNMVEGGVIFSASQEWYDIPWSISMKYINGFVELLLSCDKELNAHEAW-SIETNFQ 395

Query: 1021 FNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXX 1200
              LV  NGK L       F +    +S+  S  K+IRW+DM+  Y + DS
Sbjct: 396  LILVGANGKRLTDYFEHTFEKP---DSIGDS--KLIRWEDMLDQYAVEDSLTVEARVNF- 449

Query: 1201 XXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRI 1371
                        + E      E SF +S  V N+S   + E  +  TE   + PW +
Sbjct: 450  ----------IMLIEPQP---EYSFIMSHTVKNLSNVHEGEFHFSKTEKHCDAPWSV 493



 Score = 79.3 bits (194), Expect = 4e-13
 Identities = 49/175 (28%), Positives = 91/175 (52%), Gaps = 8/175 (4%)
 Frame = +1

Query: 1951 GDSKLIRWEDMLDQYAVEDSLTVEARVN-FTL----LIEPQPEYSFIMCHTVKKLSNVRE 2115
            G  KL++WE ++  + V DS+TVEA +N F L    + +      F++      +S + E
Sbjct: 3    GYRKLMKWEKLVSNHLVNDSVTVEADLNVFNLAGYKIFDKSTTKKFVLSQQFSDVSRIEE 62

Query: 2116 GEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDEN--WSIQVEVQLVLGSETG 2289
            GE  FS+ E   + PWRI L++    + I+LH    +   ++    I+ +    L S  G
Sbjct: 63   GESRFSRFEKRFNIPWRIELQRVSGFLEIHLHRGIEIEKPDDVFTIIKADCWFNLVSTNG 122

Query: 2290 RTLTDKVTHIFNEPEGIHWTKD-LTWEDLERDFMVDDSVKIEARVKIVKPVEIDN 2451
            + L  +++ +F     +   K  + W+D+  D++++DS  IEA ++I++ +E  N
Sbjct: 123  KNLMRQMSAVFCRDVDMESLKKVIRWDDMMTDYVINDSFIIEAHIEILRIIEKKN 177



 Score = 54.7 bits (130), Expect = 1e-05
 Identities = 39/171 (22%), Positives = 75/171 (43%)
 Frame = +1

Query: 22  FSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKDCQ 201
           F M + ++NVS    G + FS    W ++ W + +  ++ F+ + + C +  N   +
Sbjct: 331 FLMSHVVRNVSNMVEGGVIFSASQEWYDIPWSISMKYINGFVELLLSCDKELNAH-EAWS 389

Query: 202 IVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKIV 381
           I    +  +V  NG+     RL +       +   I   + ++W++M   +   DS+ +
Sbjct: 390 IETNFQLILVGANGK-----RLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVE 444

Query: 382 VIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRIC 534
             VN F  L +      F + HT K+L+   E E  FS +++     W +C
Sbjct: 445 ARVN-FIMLIEPQPEYSFIMSHTVKNLSNVHEGEFHFSKTEKHCDAPWSVC 494


>gi|32564807|ref|NP_872004.1| Meprin/TRAF-like MATH family member
            (41.1 kD) (2C59) [Caenorhabditis elegans]
 gi|28275145|gb|AAO38641.1| Hypothetical protein F36H5.2c
            [Caenorhabditis elegans]
          Length = 354

 Score =  688 bits (1776), Expect = 0.0
 Identities = 334/354 (94%), Positives = 344/354 (96%)
 Frame = +1

Query: 1402 MYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIES 1581
            MYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRT++L F+KPGGQ I +FIKWNDMIES
Sbjct: 1    MYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTTELNFKKPGGQSISEFIKWNDMIES 60

Query: 1582 FLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWY 1761
            FLNPLEDSLIVEAHVKIFMVEEFSR+FLQNERSFLMSHTVRDVSSAEEGNVVF ATEEWY
Sbjct: 61   FLNPLEDSLIVEAHVKIFMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWY 120

Query: 1762 DVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKP 1941
            DVQWSISMKYINGFVELLLSCDKDLNAHEAWSIE + Q ILVGANGKRLTDYFEHTFEKP
Sbjct: 121  DVQWSISMKYINGFVELLLSCDKDLNAHEAWSIEASVQRILVGANGKRLTDYFEHTFEKP 180

Query: 1942 DSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVKKLSNVREGE 2121
            DSIGDSKLIRWEDMLDQYAVEDSLTVEARV +T +I+PQPEYSFIMCHTVKKLSNVREGE
Sbjct: 181  DSIGDSKLIRWEDMLDQYAVEDSLTVEARVVYTKIIDPQPEYSFIMCHTVKKLSNVREGE 240

Query: 2122 FHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLT 2301
            FHFSKTE HCDAPWRISLKKEEACILIYLHCDKLLSNDE+WSIQVEVQLVLGSETGRTLT
Sbjct: 241  FHFSKTEQHCDAPWRISLKKEEACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLT 300

Query: 2302 DKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 2463
            DKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH
Sbjct: 301  DKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNEDEH 354



 Score =  169 bits (427), Expect = 4e-40
 Identities = 119/370 (32%), Positives = 178/370 (47%), Gaps = 5/370 (1%)
 Frame = +1

Query: 958  IHLHCGENATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWD 1137
            ++L C      L   I+T+   NLVSTNG +  R     F +        +S+ + I+W+
Sbjct: 1    MYLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFRRTTELNFKKPGG-----QSISEFIKWN 55

Query: 1138 DMMTDYV--INDSFXXXXXXXXXXXXXXACFWPYWITEEDAVF--HERSFYISCKVNNVS 1305
            DM+  ++  + DS                    + + E    F  +ERSF +S  V +VS
Sbjct: 56   DMIESFLNPLEDSLIVEAHVKI-----------FMVEEFSRKFLQNERSFLMSHTVRDVS 104

Query: 1306 RFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQ-LIKTEVTCNLVST 1482
               +    +  TE  Y++ W I  K    F+E+ L CD + N  +   I+  V   LV
Sbjct: 105  SAEEGNVVFCATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIEASVQRILVGA 164

Query: 1483 NGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRF 1662
            NG       +  FEKP   G  K I+W DM++ +   +EDSL VEA V    + +
Sbjct: 165  NGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQY--AVEDSLTVEARVVYTKIID----- 217

Query: 1663 LQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNA 1842
             Q E SF+M HTV+ +S+  EG   FS TE+  D  W IS+K     + + L CDK L+
Sbjct: 218  PQPEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLKKEEACILIYLHCDKLLSN 277

Query: 1843 HEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVE 2022
             E WSI+   QL+L    G+ LTD   H F +P+ I  +K + WED+   + V+DS+ +E
Sbjct: 278  DEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIE 337

Query: 2023 ARVNFTLLIE 2052
            ARV     +E
Sbjct: 338  ARVKIVKPVE 347



 Score =  124 bits (311), Expect = 1e-26
 Identities = 90/325 (27%), Positives = 151/325 (45%), Gaps = 8/325 (2%)
 Frame = +1

Query: 220  CKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTA--DSVKIVVIVN 393
            C +VS NG        LN K P    G  I   EF+KW++M ++FL    DS+ +   V
Sbjct: 22   CNLVSTNGNNFRRTTELNFKKPG---GQSIS--EFIKWNDMIESFLNPLEDSLIVEAHVK 76

Query: 394  NFTALE-DIDFLCG---FKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLG 561
             F   E    FL     F + HT + ++  EE    F  ++EW    W I +K   G++
Sbjct: 77   IFMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEWYDVQWSISMKYINGFVE 136

Query: 562  CYLQCESNPNT-SLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLIS 738
              L C+ + N      + A  +  +       + D     F +P  +G+SKL++WED++
Sbjct: 137  LLLSCDKDLNAHEAWSIEASVQRILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLD 196

Query: 739  NYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIP 918
             Y V DS+T+EA +        + +Y    F++      +S + EGE  FS  E+  + P
Sbjct: 197  QYAVEDSLTVEARVVYTKIIDPQPEY---SFIMCHTVKKLSNVREGEFHFSKTEQHCDAP 253

Query: 919  WRIELKRVSGFLEIHLHCGENATFLYH-QIETDCWFNLVSTNGKHLMRQMSAVFCRDVDM 1095
            WRI LK+    + I+LHC +  +   H  I+ +    L S  G+ L  +++ +F     +
Sbjct: 254  WRISLKKEEACILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGI 313

Query: 1096 ESLKKSLKKVIRWDDMMTDYVINDS 1170
               K      + W+D+  D++++DS
Sbjct: 314  HWTKD-----LTWEDLERDFMVDDS 333



 Score =  118 bits (295), Expect = 8e-25
 Identities = 105/365 (28%), Positives = 159/365 (42%), Gaps = 9/365 (2%)
 Frame = +1

Query: 565  YLQCESNPN--TSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLIS 738
            YL C+   N    LI     C L   +  N+       L F +P     S+ +KW D+I
Sbjct: 2    YLFCDGEGNGLDQLIKTEVTCNLVSTNGNNFR--RTTELNFKKPGGQSISEFIKWNDMIE 59

Query: 739  NYL--VSDSVTIEADLEAY--NEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEKR 906
            ++L  + DS+ +EA ++ +   EF  K     + F++S    DVS  EEG   F A E+
Sbjct: 60   SFLNPLEDSLIVEAHVKIFMVEEFSRKFLQNERSFLMSHTVRDVSSAEEGNVVFCATEEW 119

Query: 907  FNIPWRIELKRVSGFLEIHLHCGE--NATFLYHQIETDCWFNLVSTNGKHLMRQMSAVFC 1080
            +++ W I +K ++GF+E+ L C +  NA   +  IE      LV  NGK L       F
Sbjct: 120  YDVQWSISMKYINGFVELLLSCDKDLNAHEAW-SIEASVQRILVGANGKRLTDYFEHTFE 178

Query: 1081 RDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVF 1260
            +    +S+  S  K+IRW+DM+  Y + DS                       T+
Sbjct: 179  KP---DSIGDS--KLIRWEDMLDQYAVEDSLTVEARVV--------------YTKIIDPQ 219

Query: 1261 HERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDG-EGNGL 1437
             E SF +   V  +S   + E  +  TE   + PWRI  K+    + +YL CD    N
Sbjct: 220  PEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLKKEEACILIYLHCDKLLSNDE 279

Query: 1438 DQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVE 1617
               I+ EV   L S  G          F +P G    K + W D+   F+  ++DS+ +E
Sbjct: 280  HWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFM--VDDSVKIE 337

Query: 1618 AHVKI 1632
            A VKI
Sbjct: 338  ARVKI 342



 Score = 87.4 bits (215), Expect = 1e-15
 Identities = 66/268 (24%), Positives = 120/268 (44%), Gaps = 4/268 (1%)
 Frame = +1

Query: 22  FSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNT---WIK 192
           F M +T+++VS    G + F     W ++ W + +  ++ F+ + + C +  N    W
Sbjct: 94  FLMSHTVRDVSSAEEGNVVFCATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSI 153

Query: 193 DCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSV 372
           +  +  IL    V  NG+     RL +       +   I   + ++W++M   +   DS+
Sbjct: 154 EASVQRIL----VGANGK-----RLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSL 204

Query: 373 KIVVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEG 552
            +   V  +T + D      F + HT K L+   E E  FS +++     WRI +KKEE
Sbjct: 205 TVEARVV-YTKIIDPQPEYSFIMCHTVKKLSNVREGEFHFSKTEQHCDAPWRISLKKEEA 263

Query: 553 YLGCYLQCESN-PNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLMKWED 729
            +  YL C+    N     +    +L + S+    + D     F+ P  +  +K + WED
Sbjct: 264 CILIYLHCDKLLSNDEHWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWED 323

Query: 730 LISNYLVSDSVTIEADLEAYNEFPVKND 813
           L  +++V DSV IEA ++      + N+
Sbjct: 324 LERDFMVDDSVKIEARVKIVKPVEIDNE 351


>gi|17533759|ref|NP_494073.1| Meprin/TRAF-like MATH family member
            (2C55) [Caenorhabditis elegans]
 gi|7500680|pir||T25742 hypothetical protein F36H5.3 - Caenorhabditis
            elegans
          Length = 843

 Score =  654 bits (1688), Expect = 0.0
 Identities = 365/840 (43%), Positives = 517/840 (61%), Gaps = 28/840 (3%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKI-SKLDDFLGVSVYCSQT---SNTW 186
            +FS+ Y  KN+S+F AGE QFS+E +   + W+L +    D+ +G+S+ C Q    S  W
Sbjct: 20   KFSLTYAAKNLSQFVAGEKQFSNEKVLFGIPWRLVVFENHDEIVGLSLSCGQCVQDSRKW 79

Query: 187  IKDCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTAD 366
                ++    E K++S + +    +R L +K   KIE  ++D  + ++      NF++A+
Sbjct: 80   SLSIEV----ELKLMSSSEKGFSKVRRLLVKTLTKIELQLLDTEDLIE------NFVSAE 129

Query: 367  SVKIVVIVNNFTALEDIDFLCGFKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKE 546
            SV+I V V      E       F++ +  ++LARFE  E+Q SD +E     W I V+K
Sbjct: 130  SVRIQVDVKILEQKELKYETKIFELTYPIQNLARFENRESQSSDVRECFKVPWSIFVEKN 189

Query: 547  EGYLGCYLQCESN---PNTSLICVSAICELRIKSKENYEIFDLDVLEFSRPTMLGNSKLM 717
              +L C+L  E     PN   I    +C   +KS E     +   ++   P   G+   +
Sbjct: 190  HDFLSCHLMYEKELCTPNDWHI--QGVCTFYLKSDEGKSFCNFYEIDLKGPGTSGDDHFI 247

Query: 718  KWEDLISNYLVSDSVTIEADLE--AYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRFS 891
            KWEDLI NY + DSVT+ A ++  +     +K   ++K FV+SQQF  +S + EGE+
Sbjct: 248  KWEDLIRNYSIDDSVTVIARVQITSLKRSFMKEGPISKSFVISQQFGGISSVLEGETLIG 307

Query: 892  AFEKRFNIPWRIELKRVSGFLEIHLHCGENATFLYHQIET---DCWFNLVSTNGKHLMRQ 1062
            + EKRFNIPW I+++R SGF+ I L+C   +    HQI T    CWF LVS NGK LMR
Sbjct: 308  SEEKRFNIPWTIKMQRRSGFVVIFLYCRRKS--YPHQIWTVYAKCWFKLVSANGKSLMRL 365

Query: 1063 MSAVF-CRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWI 1239
             +AVF C D         L K  RW+DMMTDY I+D                     Y I
Sbjct: 366  QNAVFQCEDTC------ELDKFTRWEDMMTDYAIDDYVTIEAHVEI-----------YDI 408

Query: 1240 TEEDA--------------VFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQA 1377
             E+D                F+  SF+ +  ++N+SRF DDEKQWGNTE RY IPWR++A
Sbjct: 409  VEKDIDLLAPSLSNALDEQTFYAGSFFSAFTISNISRFEDDEKQWGNTEKRYNIPWRLRA 468

Query: 1378 KRTYDFLEMYLFCDGEG-NGLDQLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKF 1554
            K+++DFLE+ LFCD E     ++L++ E T  LVS+NGN+ ++  KL F +PGGQG+ +
Sbjct: 469  KKSFDFLEINLFCDEENIMTTNKLVEAECTFCLVSSNGNSLKQKLKLYFGRPGGQGVCRL 528

Query: 1555 IKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNV 1734
            ++W+++ E +   + D +++EAHVKI  V E S   L  ERS ++SHTVR++++ EE N
Sbjct: 529  VEWSELEEDYA--VNDRVVIEAHVKIKKVRELSHEPLPIERSCVLSHTVRNIANMEESNF 586

Query: 1735 VFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTD 1914
            +F+ TEEWY V W IS+K  +GFVEL L+ + +L  +E+W+I+T FQL L+GAN KR+T
Sbjct: 587  IFNITEEWYYVLWGISLKCNSGFVELQLNWENELFENESWTIQTRFQLSLIGANEKRITQ 646

Query: 1915 YFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIMCHTVK 2094
            YFEHTF+KP S GDSK +RWEDM++ YA+EDS+ VEA V F  +I   P+ SF M +T+
Sbjct: 647  YFEHTFDKPGSSGDSKFLRWEDMVNNYAIEDSVRVEACVRFIHVIATPPQKSFAMFYTLG 706

Query: 2095 KLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVL 2274
             LSNV E E HFS TE H + PWRIS++++  CILIYLHCDK  SN+E+WSIQ EV L+L
Sbjct: 707  NLSNVLEEEHHFSLTEKHFEIPWRISVQRKRMCILIYLHCDKPYSNNEDWSIQAEVHLIL 766

Query: 2275 GSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNE 2454
             S+TGRT TD+VTHIF +PEGI WTK L W+D+E+DFMVDDSV++EARVKIV   +++ +
Sbjct: 767  VSDTGRTSTDRVTHIFEKPEGICWTKTLNWQDMEKDFMVDDSVRVEARVKIVDVKKVEKK 826



 Score =  203 bits (517), Expect = 1e-50
 Identities = 150/578 (25%), Positives = 264/578 (44%), Gaps = 22/578 (3%)
 Frame = +1

Query: 787  YNEF--PVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWR-IELKRVSGFLE 957
            YNEF  P  +    KKF L+    ++S+   GE +FS  +  F IPWR +  +     +
Sbjct: 5    YNEFLLPAVSSGPRKKFSLTYAAKNLSQFVAGEKQFSNEKVLFGIPWRLVVFENHDEIVG 64

Query: 958  IHLHCGENA-TFLYHQIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRW 1134
            + L CG+         +  +    L+S++ K   +       R + +++L K   +++
Sbjct: 65   LSLSCGQCVQDSRKWSLSIEVELKLMSSSEKGFSK------VRRLLVKTLTKIELQLLDT 118

Query: 1135 DDMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFL 1314
            +D++ ++V  +S                      + +++  +  + F ++  + N++RF
Sbjct: 119  EDLIENFVSAESVRIQVDVKI-------------LEQKELKYETKIFELTYPIQNLARFE 165

Query: 1315 DDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGE-GNGLDQLIKTEVTCNLVSTNGN 1491
            + E Q  +    +++PW I  ++ +DFL  +L  + E     D  I+   T  L S  G
Sbjct: 166  NRESQSSDVRECFKVPWSIFVEKNHDFLSCHLMYEKELCTPNDWHIQGVCTFYLKSDEGK 225

Query: 1492 NFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQN 1671
            +F    ++  + PG  G   FIKW D+I ++   ++DS+ V A V+I  ++    +
Sbjct: 226  SFCNFYEIDLKGPGTSGDDHFIKWEDLIRNY--SIDDSVTVIARVQITSLKRSFMKEGPI 283

Query: 1672 ERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEA 1851
             +SF++S     +SS  EG  +  + E+ +++ W+I M+  +GFV + L C +    H+
Sbjct: 284  SKSFVISQQFGGISSVLEGETLIGSEEKRFNIPWTIKMQRRSGFVVIFLYCRRKSYPHQI 343

Query: 1852 WSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARV 2031
            W++       LV ANGK L       F+  D+    K  RWEDM+  YA++D +T+EA V
Sbjct: 344  WTVYAKCWFKLVSANGKSLMRLQNAVFQCEDTCELDKFTRWEDMMTDYAIDDYVTIEAHV 403

Query: 2032 NFTLLIEPQPEY-----------------SFIMCHTVKKLSNVREGEFHFSKTETHCDAP 2160
                ++E   +                  SF    T+  +S   + E  +  TE   + P
Sbjct: 404  EIYDIVEKDIDLLAPSLSNALDEQTFYAGSFFSAFTISNISRFEDDEKQWGNTEKRYNIP 463

Query: 2161 WRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFNEPEGI 2340
            WR+  KK    + I L CD+      N  ++ E    L S  G +L  K+   F  P G
Sbjct: 464  WRLRAKKSFDFLEINLFCDEENIMTTNKLVEAECTFCLVSSNGNSLKQKLKLYFGRPGGQ 523

Query: 2341 HWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEIDNE 2454
               + + W +LE D+ V+D V IEA VKI K  E+ +E
Sbjct: 524  GVCRLVEWSELEEDYAVNDRVVIEAHVKIKKVRELSHE 561



 Score =  149 bits (376), Expect = 3e-34
 Identities = 101/401 (25%), Positives = 190/401 (47%), Gaps = 7/401 (1%)
 Frame = +1

Query: 1267 RSFYISCKVNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGE--GNGLD 1440
            + F ++    N+S+F+  EKQ+ N ++ + IPWR+     +D +       G+   +
Sbjct: 19   KKFSLTYAAKNLSQFVAGEKQFSNEKVLFGIPWRLVVFENHDEIVGLSLSCGQCVQDSRK 78

Query: 1441 QLIKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEA 1620
              +  EV   L+S++   F +  +L   K   +  ++ +   D+IE+F++   +S+ ++
Sbjct: 79   WSLSIEVELKLMSSSEKGFSKVRRL-LVKTLTKIELQLLDTEDLIENFVS--AESVRIQV 135

Query: 1621 HVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYING 1800
             VKI   +E         + F +++ +++++  E      S   E + V WSI ++  +
Sbjct: 136  DVKILEQKELK----YETKIFELTYPIQNLARFENRESQSSDVRECFKVPWSIFVEKNHD 191

Query: 1801 FVELLLSCDKDLNAHEAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWED 1980
            F+   L  +K+L     W I+      L    GK   +++E   + P + GD   I+WED
Sbjct: 192  FLSCHLMYEKELCTPNDWHIQGVCTFYLKSDEGKSFCNFYEIDLKGPGTSGDDHFIKWED 251

Query: 1981 MLDQYAVEDSLTVEARVNFT-----LLIEPQPEYSFIMCHTVKKLSNVREGEFHFSKTET 2145
            ++  Y+++DS+TV ARV  T      + E     SF++      +S+V EGE      E
Sbjct: 252  LIRNYSIDDSVTVIARVQITSLKRSFMKEGPISKSFVISQQFGGISSVLEGETLIGSEEK 311

Query: 2146 HCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVEVQLVLGSETGRTLTDKVTHIFN 2325
              + PW I +++    ++I+L+C +     + W++  +    L S  G++L      +F
Sbjct: 312  RFNIPWTIKMQRRSGFVVIFLYCRRKSYPHQIWTVYAKCWFKLVSANGKSLMRLQNAVFQ 371

Query: 2326 EPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPVEID 2448
              +     K   WED+  D+ +DD V IEA V+I   VE D
Sbjct: 372  CEDTCELDKFTRWEDMMTDYAIDDYVTIEAHVEIYDIVEKD 412


>gi|32564795|ref|NP_494077.2| Meprin/TRAF-like MATH family member
            (2C70) [Caenorhabditis elegans]
 gi|22532984|gb|AAM98053.1| Hypothetical protein C08F1.5
            [Caenorhabditis elegans]
          Length = 905

 Score =  651 bits (1679), Expect = 0.0
 Identities = 350/662 (52%), Positives = 452/662 (67%), Gaps = 22/662 (3%)
 Frame = +1

Query: 526  RICVKKEEGYLGCYLQCESNPNTSLICVSAI---CELRIKSKENYEIFDLDVLEFS---- 684
            RI   K++G+ G YLQ E+N +TS    + I   C L I  KE +   D     F
Sbjct: 252  RIGAMKKDGFFGFYLQYENNLHTSTDYSATIEPNCWLGILPKERHGQPDGKFNSFPSEFD 311

Query: 685  -RPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVS 861
             R T +GN K+++W++L   Y+V+DSV I A L     +  K D  A+KFVLSQ+F DVS
Sbjct: 312  HRNTRVGNMKMIEWKELRKKYMVNDSVVIAAVLPKVYVYSKKQDRFARKFVLSQKFSDVS 371

Query: 862  RIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGE------NATFLYHQIETDCWF 1023
             I EGESRF + EKRFNIPWR+ELKR SGFL +HLHC E      NA +   +I  +C F
Sbjct: 372  NIAEGESRFGSSEKRFNIPWRVELKRESGFLAVHLHCEEGSRKSDNAVW---EIIVNCVF 428

Query: 1024 NLVSTNGKHLMRQMSAVFCRDV-DMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXX 1200
            NLVS NG++LMR++ +     V    + K+ + K IRWDDMMTDYV+++
Sbjct: 429  NLVSANGRNLMRRVESAKSDTVFHRNNEKEGITKFIRWDDMMTDYVVSNFVIIEARVDMC 488

Query: 1201 XXXXXACFWP------YWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIP 1362
                   F P        +++ + V H   F+++C VNNVS+F D EKQW +TE R+ +
Sbjct: 489  WCKDGDIFEPDHRSDTKLMSDTEFVGH---FFLACTVNNVSKFQDGEKQWSDTETRHNLQ 545

Query: 1363 WRIQAKRTYDFLEMYLFCDGEGNGLDQL-IKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQ 1539
            WRIQA +  DFL ++LFCD      +   I+TEVT NLVSTNG+N+++ + L FEK GGQ
Sbjct: 546  WRIQAIKKADFLGIFLFCDNAYESHEGWSIQTEVTFNLVSTNGHNYKQAAMLKFEKAGGQ 605

Query: 1540 GIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSA 1719
            GI +FIKW+++IE++ NPL+D+LIVEAHVK++ ++        + +SFLMSH VR+VS+
Sbjct: 606  GITEFIKWDNVIETYFNPLKDNLIVEAHVKVYFIKGVPHEIPPDRKSFLMSHVVRNVSNM 665

Query: 1720 EEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANG 1899
            EE NV+FSA++EW     S+SMK  NGFVELLLSCDK+   +E W I+  FQL+LVGA+
Sbjct: 666  EEENVIFSASQEW-----SMSMKNNNGFVELLLSCDKEHTENEIWCIQAKFQLMLVGADD 720

Query: 1900 KRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIM 2079
            K LTD+ EH FE  +S GDSK+IRWEDML QY V+DS+T +ARV FT + +  P YSF M
Sbjct: 721  KILTDFCEHNFENAESAGDSKVIRWEDMLSQYVVDDSVTFKARVVFTHITDLLPSYSFTM 780

Query: 2080 CHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVE 2259
              T+K + NV+EGE +FS TE HCDAPWRIS  KE++CILIYLHCDK L NDE+WSI+VE
Sbjct: 781  LLTLKDIPNVQEGESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCNDEHWSIKVE 840

Query: 2260 VQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPV 2439
             QLVL S+TGRTLTDKVTHIF  PEGIHWTKDLTWE+LE+DFMVDDSVKIEARVKIV+
Sbjct: 841  AQLVLVSDTGRTLTDKVTHIFERPEGIHWTKDLTWENLEKDFMVDDSVKIEARVKIVEHA 900

Query: 2440 EI 2445
            E+
Sbjct: 901  EV 902



 Score =  197 bits (500), Expect = 1e-48
 Identities = 161/602 (26%), Positives = 277/602 (45%), Gaps = 31/602 (5%)
 Frame = +1

Query: 319  EFLKWDEMKKNFLTADSVKIVVI---VNNFTALEDIDFLCGFKILHTFKHLARFEENETQ 489
            + ++W E++K ++  DSV I  +   V  ++  +D  F   F +   F  ++   E E++
Sbjct: 321  KMIEWKELRKKYMVNDSVVIAAVLPKVYVYSKKQD-RFARKFVLSQKFSDVSNIAEGESR 379

Query: 490  FSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTS-----LICVSAICELRIKSKEN-- 648
            F  S++     WR+ +K+E G+L  +L CE     S      I V+ +  L   +  N
Sbjct: 380  FGSSEKRFNIPWRVELKRESGFLAVHLHCEEGSRKSDNAVWEIIVNCVFNLVSANGRNLM 439

Query: 649  --YEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEA------------ 786
               E    D +        G +K ++W+D++++Y+VS+ V IEA ++
Sbjct: 440  RRVESAKSDTVFHRNNEKEGITKFIRWDDMMTDYVVSNFVIIEARVDMCWCKDGDIFEPD 499

Query: 787  -YNEFPVKND-YMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEI 960
              ++  + +D      F L+    +VS+ ++GE ++S  E R N+ WRI+  + + FL I
Sbjct: 500  HRSDTKLMSDTEFVGHFFLACTVNNVSKFQDGEKQWSDTETRHNLQWRIQAIKKADFLGI 559

Query: 961  HLHCGENATFLYH--QIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRW 1134
             L C +NA   +    I+T+  FNLVSTNG +  +     F      ++  + + + I+W
Sbjct: 560  FLFC-DNAYESHEGWSIQTEVTFNLVSTNGHNYKQAAMLKF-----EKAGGQGITEFIKW 613

Query: 1135 DDMMTDYV--INDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSR 1308
            D+++  Y   + D+                   P+ I  +      +SF +S  V NVS
Sbjct: 614  DNVIETYFNPLKDNLIVEAHVKVYFIKGV----PHEIPPD-----RKSFLMSHVVRNVSN 664

Query: 1309 FLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLD-QLIKTEVTCNLVSTN 1485
              ++     N        W +  K    F+E+ L CD E    +   I+ +    LV  +
Sbjct: 665  MEEE-----NVIFSASQEWSMSMKNNNGFVELLLSCDKEHTENEIWCIQAKFQLMLVGAD 719

Query: 1486 GNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFL 1665
                    +  FE     G  K I+W DM+  ++  ++DS+  +A V    + +     L
Sbjct: 720  DKILTDFCEHNFENAESAGDSKVIRWEDMLSQYV--VDDSVTFKARVVFTHITD-----L 772

Query: 1666 QNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAH 1845
                SF M  T++D+ + +EG   FS TE+  D  W IS       + + L CDK L
Sbjct: 773  LPSYSFTMLLTLKDIPNVQEGESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCND 832

Query: 1846 EAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEA 2025
            E WSI+   QL+LV   G+ LTD   H FE+P+ I  +K + WE++   + V+DS+ +EA
Sbjct: 833  EHWSIKVEAQLVLVSDTGRTLTDKVTHIFERPEGIHWTKDLTWENLEKDFMVDDSVKIEA 892

Query: 2026 RV 2031
            RV
Sbjct: 893  RV 894



 Score =  146 bits (368), Expect = 3e-33
 Identities = 138/586 (23%), Positives = 246/586 (41%), Gaps = 48/586 (8%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSN-----T 183
            +F +     +VS  + GE +F       N+ W++++ +   FL V ++C + S
Sbjct: 360  KFVLSQKFSDVSNIAEGESRFGSSEKRFNIPWRVELKRESGFLAVHLHCEEGSRKSDNAV 419

Query: 184  WIKDCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMID-----------FREFLK 330
            W    +I+      +VS NG         N+   R++E    D             +F++
Sbjct: 420  W----EIIVNCVFNLVSANGR--------NLM--RRVESAKSDTVFHRNNEKEGITKFIR 465

Query: 331  WDEMKKNFLTADSVKIVVIVN----------------NFTALEDIDFLCGFKILHTFKHL 462
            WD+M  +++ ++ V I   V+                +   + D +F+  F +  T  ++
Sbjct: 466  WDDMMTDYVVSNFVIIEARVDMCWCKDGDIFEPDHRSDTKLMSDTEFVGHFFLACTVNNV 525

Query: 463  ARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQC----ESNPNTSLICVSAICELR 630
            ++F++ E Q+SD++      WRI   K+  +LG +L C    ES+   S   +
Sbjct: 526  SKFQDGEKQWSDTETRHNLQWRIQAIKKADFLGIFLFCDNAYESHEGWS---IQTEVTFN 582

Query: 631  IKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYL--VSDSVTIEADLEAY--NEF 798
            + S   +      +L+F +    G ++ +KW+++I  Y   + D++ +EA ++ Y
Sbjct: 583  LVSTNGHNYKQAAMLKFEKAGGQGITEFIKWDNVIETYFNPLKDNLIVEAHVKVYFIKGV 642

Query: 799  PVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGE 978
            P +     K F++S    +VS +EE    FSA ++     W + +K  +GF+E+ L C +
Sbjct: 643  PHEIPPDRKSFLMSHVVRNVSNMEEENVIFSASQE-----WSMSMKNNNGFVELLLSCDK 697

Query: 979  NATFLYHQIETDCW-------FNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWD 1137
              T      E + W         LV  + K L       FC      +      KVIRW+
Sbjct: 698  EHT------ENEIWCIQAKFQLMLVGADDKIL-----TDFCEHNFENAESAGDSKVIRWE 746

Query: 1138 DMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLD 1317
            DM++ YV++DS                       T    +    SF +   + ++    +
Sbjct: 747  DMLSQYVVDDSVTFKARVV--------------FTHITDLLPSYSFTMLLTLKDIPNVQE 792

Query: 1318 DEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGE-GNGLDQLIKTEVTCNLVSTNGNN 1494
             E  + NTE   + PWRI A +    + +YL CD    N     IK E    LVS  G
Sbjct: 793  GESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCNDEHWSIKVEAQLVLVSDTGRT 852

Query: 1495 FRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKI 1632
                    FE+P G    K + W ++ + F+  ++DS+ +EA VKI
Sbjct: 853  LTDKVTHIFERPEGIHWTKDLTWENLEKDFM--VDDSVKIEARVKI 896



 Score =  144 bits (364), Expect = 8e-33
 Identities = 80/177 (45%), Positives = 103/177 (57%), Gaps = 1/177 (0%)
 Frame = +1

Query: 28  MEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKDCQIV 207
           + YTI+NVS FS  E +FSDE +WR +IWKL+++K D FLGV +YCS  S      CQI
Sbjct: 8   LPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQIS 67

Query: 208 GILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKIVVI 387
             +E KIVS NG+ H    + N +    +E P+  F  F+KW EM +NFL ADS KI V
Sbjct: 68  AKVEYKIVSANGKIHSESGVANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKIEVH 127

Query: 388 VNNFTALEDIDFLCG-FKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGY 555
           V N   LE +    G     HT K+++R EENE QF DSK     SW      +EG+
Sbjct: 128 VQNLEFLEAMLIDRGEVSFFHTVKNVSRLEENEVQFGDSKACGQASWFDFYFVKEGF 184



 Score = 63.2 bits (152), Expect = 3e-08
 Identities = 48/169 (28%), Positives = 78/169 (45%), Gaps = 8/169 (4%)
 Frame = +1

Query: 1291 VNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQL--IKTEVT 1464
            + NVS F D+E ++ +  +  ++ W+++  ++  FL ++L+C      L     I  +V
Sbjct: 12   IENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQISAKVE 71

Query: 1465 CNLVSTNGNNFRRT------SKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHV 1626
              +VS NG     +      +K   EKP       FIKW +M E+FL  + DS  +E HV
Sbjct: 72   YKIVSANGKIHSESGVANSETKPSMEKPI-HSFPNFIKWREMDENFL--IADSAKIEVHV 128

Query: 1627 KIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQW 1773
            +     EF    L +       HTV++VS  EE  V F  ++      W
Sbjct: 129  QNL---EFLEAMLIDRGEVSFFHTVKNVSRLEENEVQFGDSKACGQASW 174



 Score = 54.7 bits (130), Expect = 1e-05
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
 Frame = +1

Query: 445 HTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLIC----VS 612
           +T ++++ F + E +FSD   W    W++ V K +G+LG +L C S P + ++C    +S
Sbjct: 10  YTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYC-SLP-SGILCNKCQIS 67

Query: 613 AICELRIKSKENYEIFDLDVLEF-SRPTM----LGNSKLMKWEDLISNYLVSDSVTIEAD 777
           A  E +I S       +  V    ++P+M          +KW ++  N+L++DS  IE
Sbjct: 68  AKVEYKIVSANGKIHSESGVANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKIEVH 127

Query: 778 LEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRF 888
           ++   EF         +        +VSR+EE E +F
Sbjct: 128 VQNL-EFLEAMLIDRGEVSFFHTVKNVSRLEENEVQF 163



 Score = 50.1 bits (118), Expect = 3e-04
 Identities = 42/171 (24%), Positives = 72/171 (41%), Gaps = 11/171 (6%)
 Frame = +1

Query: 1684 LMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLN-AHEAWSI 1860
            L+ +T+ +VS+  +    FS    W  + W + +   +GF+ + L C            I
Sbjct: 7    LLPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQI 66

Query: 1861 ETNFQLILVGANGKRLTD------YFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVE 2022
                +  +V ANGK  ++        + + EKP        I+W +M + + + DS  +E
Sbjct: 67   SAKVEYKIVSANGKIHSESGVANSETKPSMEKPIH-SFPNFIKWREMDENFLIADSAKIE 125

Query: 2023 ARVNFTLLIE----PQPEYSFIMCHTVKKLSNVREGEFHFSKTETHCDAPW 2163
              V     +E     + E SF   HTVK +S + E E  F  ++    A W
Sbjct: 126  VHVQNLEFLEAMLIDRGEVSFF--HTVKNVSRLEENEVQFGDSKACGQASW 174



 Score = 45.4 bits (106), Expect = 0.006
 Identities = 45/182 (24%), Positives = 77/182 (41%), Gaps = 2/182 (1%)
 Frame = +1

Query: 826  KFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFLYH-- 999
            + +L     +VS   + E+RFS       + W++E+ +  GFL + L+C   +  L +
Sbjct: 5    QLLLPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKC 64

Query: 1000 QIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXX 1179
            QI     + +VS NGK       A       ME    S    I+W +M  +++I DS
Sbjct: 65   QISAKVEYKIVSANGKIHSESGVANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKI 124

Query: 1180 XXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEI 1359
                          F    + +   V    SF+ +  V NVSR  ++E Q+G+++   +
Sbjct: 125  EVHVQNLE------FLEAMLIDRGEV----SFFHT--VKNVSRLEENEVQFGDSKACGQA 172

Query: 1360 PW 1365
             W
Sbjct: 173  SW 174



 Score = 42.4 bits (98), Expect = 0.054
 Identities = 30/131 (22%), Positives = 65/131 (48%), Gaps = 8/131 (6%)
 Frame = +1

Query: 2074 IMCHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDK---LLSNDENW 2244
            ++ +T++ +SN  + E  FS         W++ + K +  + ++L+C     +L N
Sbjct: 7    LLPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQI 66

Query: 2245 SIQVEVQLV-----LGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKI 2409
            S +VE ++V     + SE+G  + +  T    E     +   + W +++ +F++ DS KI
Sbjct: 67   SAKVEYKIVSANGKIHSESG--VANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKI 124

Query: 2410 EARVKIVKPVE 2442
            E  V+ ++ +E
Sbjct: 125  EVHVQNLEFLE 135



 Score = 40.0 bits (92), Expect = 0.27
 Identities = 36/130 (27%), Positives = 60/130 (45%), Gaps = 6/130 (4%)
 Frame = +1

Query: 7    LSKCEFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQ---TS 177
            L    F+M  T+K++     GE  FS+     +  W++  +K    + + ++C +
Sbjct: 773  LPSYSFTMLLTLKDIPNVQEGESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCND 832

Query: 178  NTW-IK-DCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPM-IDFREFLKWDEMKK 348
              W IK + Q+V      +VSD G T      L  K     E P  I + + L W+ ++K
Sbjct: 833  EHWSIKVEAQLV------LVSDTGRT------LTDKVTHIFERPEGIHWTKDLTWENLEK 880

Query: 349  NFLTADSVKI 378
            +F+  DSVKI
Sbjct: 881  DFMVDDSVKI 890


>gi|7495681|pir||T32338 hypothetical protein C08F1.5 - Caenorhabditis
            elegans
          Length = 1369

 Score =  651 bits (1679), Expect = 0.0
 Identities = 350/662 (52%), Positives = 452/662 (67%), Gaps = 22/662 (3%)
 Frame = +1

Query: 526  RICVKKEEGYLGCYLQCESNPNTSLICVSAI---CELRIKSKENYEIFDLDVLEFS---- 684
            RI   K++G+ G YLQ E+N +TS    + I   C L I  KE +   D     F
Sbjct: 716  RIGAMKKDGFFGFYLQYENNLHTSTDYSATIEPNCWLGILPKERHGQPDGKFNSFPSEFD 775

Query: 685  -RPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEAYNEFPVKNDYMAKKFVLSQQFYDVS 861
             R T +GN K+++W++L   Y+V+DSV I A L     +  K D  A+KFVLSQ+F DVS
Sbjct: 776  HRNTRVGNMKMIEWKELRKKYMVNDSVVIAAVLPKVYVYSKKQDRFARKFVLSQKFSDVS 835

Query: 862  RIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGE------NATFLYHQIETDCWF 1023
             I EGESRF + EKRFNIPWR+ELKR SGFL +HLHC E      NA +   +I  +C F
Sbjct: 836  NIAEGESRFGSSEKRFNIPWRVELKRESGFLAVHLHCEEGSRKSDNAVW---EIIVNCVF 892

Query: 1024 NLVSTNGKHLMRQMSAVFCRDV-DMESLKKSLKKVIRWDDMMTDYVINDSFXXXXXXXXX 1200
            NLVS NG++LMR++ +     V    + K+ + K IRWDDMMTDYV+++
Sbjct: 893  NLVSANGRNLMRRVESAKSDTVFHRNNEKEGITKFIRWDDMMTDYVVSNFVIIEARVDMC 952

Query: 1201 XXXXXACFWP------YWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEIP 1362
                   F P        +++ + V H   F+++C VNNVS+F D EKQW +TE R+ +
Sbjct: 953  WCKDGDIFEPDHRSDTKLMSDTEFVGH---FFLACTVNNVSKFQDGEKQWSDTETRHNLQ 1009

Query: 1363 WRIQAKRTYDFLEMYLFCDGEGNGLDQL-IKTEVTCNLVSTNGNNFRRTSKLCFEKPGGQ 1539
            WRIQA +  DFL ++LFCD      +   I+TEVT NLVSTNG+N+++ + L FEK GGQ
Sbjct: 1010 WRIQAIKKADFLGIFLFCDNAYESHEGWSIQTEVTFNLVSTNGHNYKQAAMLKFEKAGGQ 1069

Query: 1540 GIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFLQNERSFLMSHTVRDVSSA 1719
            GI +FIKW+++IE++ NPL+D+LIVEAHVK++ ++        + +SFLMSH VR+VS+
Sbjct: 1070 GITEFIKWDNVIETYFNPLKDNLIVEAHVKVYFIKGVPHEIPPDRKSFLMSHVVRNVSNM 1129

Query: 1720 EEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAHEAWSIETNFQLILVGANG 1899
            EE NV+FSA++EW     S+SMK  NGFVELLLSCDK+   +E W I+  FQL+LVGA+
Sbjct: 1130 EEENVIFSASQEW-----SMSMKNNNGFVELLLSCDKEHTENEIWCIQAKFQLMLVGADD 1184

Query: 1900 KRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEARVNFTLLIEPQPEYSFIM 2079
            K LTD+ EH FE  +S GDSK+IRWEDML QY V+DS+T +ARV FT + +  P YSF M
Sbjct: 1185 KILTDFCEHNFENAESAGDSKVIRWEDMLSQYVVDDSVTFKARVVFTHITDLLPSYSFTM 1244

Query: 2080 CHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDKLLSNDENWSIQVE 2259
              T+K + NV+EGE +FS TE HCDAPWRIS  KE++CILIYLHCDK L NDE+WSI+VE
Sbjct: 1245 LLTLKDIPNVQEGESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCNDEHWSIKVE 1304

Query: 2260 VQLVLGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKIEARVKIVKPV 2439
             QLVL S+TGRTLTDKVTHIF  PEGIHWTKDLTWE+LE+DFMVDDSVKIEARVKIV+
Sbjct: 1305 AQLVLVSDTGRTLTDKVTHIFERPEGIHWTKDLTWENLEKDFMVDDSVKIEARVKIVEHA 1364

Query: 2440 EI 2445
            E+
Sbjct: 1365 EV 1366



 Score =  197 bits (500), Expect = 1e-48
 Identities = 161/602 (26%), Positives = 277/602 (45%), Gaps = 31/602 (5%)
 Frame = +1

Query: 319  EFLKWDEMKKNFLTADSVKIVVI---VNNFTALEDIDFLCGFKILHTFKHLARFEENETQ 489
            + ++W E++K ++  DSV I  +   V  ++  +D  F   F +   F  ++   E E++
Sbjct: 785  KMIEWKELRKKYMVNDSVVIAAVLPKVYVYSKKQD-RFARKFVLSQKFSDVSNIAEGESR 843

Query: 490  FSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTS-----LICVSAICELRIKSKEN-- 648
            F  S++     WR+ +K+E G+L  +L CE     S      I V+ +  L   +  N
Sbjct: 844  FGSSEKRFNIPWRVELKRESGFLAVHLHCEEGSRKSDNAVWEIIVNCVFNLVSANGRNLM 903

Query: 649  --YEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYLVSDSVTIEADLEA------------ 786
               E    D +        G +K ++W+D++++Y+VS+ V IEA ++
Sbjct: 904  RRVESAKSDTVFHRNNEKEGITKFIRWDDMMTDYVVSNFVIIEARVDMCWCKDGDIFEPD 963

Query: 787  -YNEFPVKND-YMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEI 960
              ++  + +D      F L+    +VS+ ++GE ++S  E R N+ WRI+  + + FL I
Sbjct: 964  HRSDTKLMSDTEFVGHFFLACTVNNVSKFQDGEKQWSDTETRHNLQWRIQAIKKADFLGI 1023

Query: 961  HLHCGENATFLYH--QIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRW 1134
             L C +NA   +    I+T+  FNLVSTNG +  +     F      ++  + + + I+W
Sbjct: 1024 FLFC-DNAYESHEGWSIQTEVTFNLVSTNGHNYKQAAMLKF-----EKAGGQGITEFIKW 1077

Query: 1135 DDMMTDYV--INDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSR 1308
            D+++  Y   + D+                   P+ I  +      +SF +S  V NVS
Sbjct: 1078 DNVIETYFNPLKDNLIVEAHVKVYFIKGV----PHEIPPD-----RKSFLMSHVVRNVSN 1128

Query: 1309 FLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLD-QLIKTEVTCNLVSTN 1485
              ++     N        W +  K    F+E+ L CD E    +   I+ +    LV  +
Sbjct: 1129 MEEE-----NVIFSASQEWSMSMKNNNGFVELLLSCDKEHTENEIWCIQAKFQLMLVGAD 1183

Query: 1486 GNNFRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKIFMVEEFSRRFL 1665
                    +  FE     G  K I+W DM+  ++  ++DS+  +A V    + +     L
Sbjct: 1184 DKILTDFCEHNFENAESAGDSKVIRWEDMLSQYV--VDDSVTFKARVVFTHITD-----L 1236

Query: 1666 QNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFVELLLSCDKDLNAH 1845
                SF M  T++D+ + +EG   FS TE+  D  W IS       + + L CDK L
Sbjct: 1237 LPSYSFTMLLTLKDIPNVQEGESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCND 1296

Query: 1846 EAWSIETNFQLILVGANGKRLTDYFEHTFEKPDSIGDSKLIRWEDMLDQYAVEDSLTVEA 2025
            E WSI+   QL+LV   G+ LTD   H FE+P+ I  +K + WE++   + V+DS+ +EA
Sbjct: 1297 EHWSIKVEAQLVLVSDTGRTLTDKVTHIFERPEGIHWTKDLTWENLEKDFMVDDSVKIEA 1356

Query: 2026 RV 2031
            RV
Sbjct: 1357 RV 1358



 Score =  146 bits (368), Expect = 3e-33
 Identities = 138/586 (23%), Positives = 246/586 (41%), Gaps = 48/586 (8%)
 Frame = +1

Query: 19   EFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSN-----T 183
            +F +     +VS  + GE +F       N+ W++++ +   FL V ++C + S
Sbjct: 824  KFVLSQKFSDVSNIAEGESRFGSSEKRFNIPWRVELKRESGFLAVHLHCEEGSRKSDNAV 883

Query: 184  WIKDCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPMID-----------FREFLK 330
            W    +I+      +VS NG         N+   R++E    D             +F++
Sbjct: 884  W----EIIVNCVFNLVSANGR--------NLM--RRVESAKSDTVFHRNNEKEGITKFIR 929

Query: 331  WDEMKKNFLTADSVKIVVIVN----------------NFTALEDIDFLCGFKILHTFKHL 462
            WD+M  +++ ++ V I   V+                +   + D +F+  F +  T  ++
Sbjct: 930  WDDMMTDYVVSNFVIIEARVDMCWCKDGDIFEPDHRSDTKLMSDTEFVGHFFLACTVNNV 989

Query: 463  ARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQC----ESNPNTSLICVSAICELR 630
            ++F++ E Q+SD++      WRI   K+  +LG +L C    ES+   S   +
Sbjct: 990  SKFQDGEKQWSDTETRHNLQWRIQAIKKADFLGIFLFCDNAYESHEGWS---IQTEVTFN 1046

Query: 631  IKSKENYEIFDLDVLEFSRPTMLGNSKLMKWEDLISNYL--VSDSVTIEADLEAY--NEF 798
            + S   +      +L+F +    G ++ +KW+++I  Y   + D++ +EA ++ Y
Sbjct: 1047 LVSTNGHNYKQAAMLKFEKAGGQGITEFIKWDNVIETYFNPLKDNLIVEAHVKVYFIKGV 1106

Query: 799  PVKNDYMAKKFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGE 978
            P +     K F++S    +VS +EE    FSA ++     W + +K  +GF+E+ L C +
Sbjct: 1107 PHEIPPDRKSFLMSHVVRNVSNMEEENVIFSASQE-----WSMSMKNNNGFVELLLSCDK 1161

Query: 979  NATFLYHQIETDCW-------FNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWD 1137
              T      E + W         LV  + K L       FC      +      KVIRW+
Sbjct: 1162 EHT------ENEIWCIQAKFQLMLVGADDKIL-----TDFCEHNFENAESAGDSKVIRWE 1210

Query: 1138 DMMTDYVINDSFXXXXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLD 1317
            DM++ YV++DS                       T    +    SF +   + ++    +
Sbjct: 1211 DMLSQYVVDDSVTFKARVV--------------FTHITDLLPSYSFTMLLTLKDIPNVQE 1256

Query: 1318 DEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGE-GNGLDQLIKTEVTCNLVSTNGNN 1494
             E  + NTE   + PWRI A +    + +YL CD    N     IK E    LVS  G
Sbjct: 1257 GESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCNDEHWSIKVEAQLVLVSDTGRT 1316

Query: 1495 FRRTSKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHVKI 1632
                    FE+P G    K + W ++ + F+  ++DS+ +EA VKI
Sbjct: 1317 LTDKVTHIFERPEGIHWTKDLTWENLEKDFM--VDDSVKIEARVKI 1360



 Score =  144 bits (364), Expect = 8e-33
 Identities = 80/177 (45%), Positives = 103/177 (57%), Gaps = 1/177 (0%)
 Frame = +1

Query: 28   MEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQTSNTWIKDCQIV 207
            + YTI+NVS FS  E +FSDE +WR +IWKL+++K D FLGV +YCS  S      CQI
Sbjct: 472  LPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQIS 531

Query: 208  GILECKIVSDNGETHEGIRLLNMKPPRKIEGPMIDFREFLKWDEMKKNFLTADSVKIVVI 387
              +E KIVS NG+ H    + N +    +E P+  F  F+KW EM +NFL ADS KI V
Sbjct: 532  AKVEYKIVSANGKIHSESGVANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKIEVH 591

Query: 388  VNNFTALEDIDFLCG-FKILHTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGY 555
            V N   LE +    G     HT K+++R EENE QF DSK     SW      +EG+
Sbjct: 592  VQNLEFLEAMLIDRGEVSFFHTVKNVSRLEENEVQFGDSKACGQASWFDFYFVKEGF 648



 Score = 63.2 bits (152), Expect = 3e-08
 Identities = 48/169 (28%), Positives = 78/169 (45%), Gaps = 8/169 (4%)
 Frame = +1

Query: 1291 VNNVSRFLDDEKQWGNTELRYEIPWRIQAKRTYDFLEMYLFCDGEGNGLDQL--IKTEVT 1464
            + NVS F D+E ++ +  +  ++ W+++  ++  FL ++L+C      L     I  +V
Sbjct: 476  IENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQISAKVE 535

Query: 1465 CNLVSTNGNNFRRT------SKLCFEKPGGQGIIKFIKWNDMIESFLNPLEDSLIVEAHV 1626
              +VS NG     +      +K   EKP       FIKW +M E+FL  + DS  +E HV
Sbjct: 536  YKIVSANGKIHSESGVANSETKPSMEKPI-HSFPNFIKWREMDENFL--IADSAKIEVHV 592

Query: 1627 KIFMVEEFSRRFLQNERSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQW 1773
            +     EF    L +       HTV++VS  EE  V F  ++      W
Sbjct: 593  QNL---EFLEAMLIDRGEVSFFHTVKNVSRLEENEVQFGDSKACGQASW 638



 Score = 54.7 bits (130), Expect = 1e-05
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 9/157 (5%)
 Frame = +1

Query: 445 HTFKHLARFEENETQFSDSKEWAGTSWRICVKKEEGYLGCYLQCESNPNTSLIC----VS 612
           +T ++++ F + E +FSD   W    W++ V K +G+LG +L C S P + ++C    +S
Sbjct: 474 YTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYC-SLP-SGILCNKCQIS 531

Query: 613 AICELRIKSKENYEIFDLDVLEF-SRPTM----LGNSKLMKWEDLISNYLVSDSVTIEAD 777
           A  E +I S       +  V    ++P+M          +KW ++  N+L++DS  IE
Sbjct: 532 AKVEYKIVSANGKIHSESGVANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKIEVH 591

Query: 778 LEAYNEFPVKNDYMAKKFVLSQQFYDVSRIEEGESRF 888
           ++   EF         +        +VSR+EE E +F
Sbjct: 592 VQNL-EFLEAMLIDRGEVSFFHTVKNVSRLEENEVQF 627



 Score = 50.8 bits (120), Expect = 2e-04
 Identities = 47/190 (24%), Positives = 78/190 (40%), Gaps = 15/190 (7%)
 Frame = +1

Query: 1639 VEEFSRRFLQNE----RSFLMSHTVRDVSSAEEGNVVFSATEEWYDVQWSISMKYINGFV 1806
            VE  S +F  N        L+ +T+ +VS+  +    FS    W  + W + +   +GF+
Sbjct: 452  VEPTSGKFCFNSVMDTSQLLLPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFL 511

Query: 1807 ELLLSCDKDLN-AHEAWSIETNFQLILVGANGKRLTD------YFEHTFEKPDSIGDSKL 1965
             + L C            I    +  +V ANGK  ++        + + EKP
Sbjct: 512  GVFLYCSLPSGILCNKCQISAKVEYKIVSANGKIHSESGVANSETKPSMEKPIH-SFPNF 570

Query: 1966 IRWEDMLDQYAVEDSLTVEARVNFTLLIE----PQPEYSFIMCHTVKKLSNVREGEFHFS 2133
            I+W +M + + + DS  +E  V     +E     + E SF   HTVK +S + E E  F
Sbjct: 571  IKWREMDENFLIADSAKIEVHVQNLEFLEAMLIDRGEVSFF--HTVKNVSRLEENEVQFG 628

Query: 2134 KTETHCDAPW 2163
             ++    A W
Sbjct: 629  DSKACGQASW 638



 Score = 45.4 bits (106), Expect = 0.006
 Identities = 45/182 (24%), Positives = 77/182 (41%), Gaps = 2/182 (1%)
 Frame = +1

Query: 826  KFVLSQQFYDVSRIEEGESRFSAFEKRFNIPWRIELKRVSGFLEIHLHCGENATFLYH-- 999
            + +L     +VS   + E+RFS       + W++E+ +  GFL + L+C   +  L +
Sbjct: 469  QLLLPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKC 528

Query: 1000 QIETDCWFNLVSTNGKHLMRQMSAVFCRDVDMESLKKSLKKVIRWDDMMTDYVINDSFXX 1179
            QI     + +VS NGK       A       ME    S    I+W +M  +++I DS
Sbjct: 529  QISAKVEYKIVSANGKIHSESGVANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKI 588

Query: 1180 XXXXXXXXXXXXACFWPYWITEEDAVFHERSFYISCKVNNVSRFLDDEKQWGNTELRYEI 1359
                          F    + +   V    SF+ +  V NVSR  ++E Q+G+++   +
Sbjct: 589  EVHVQNLE------FLEAMLIDRGEV----SFFHT--VKNVSRLEENEVQFGDSKACGQA 636

Query: 1360 PW 1365
             W
Sbjct: 637  SW 638



 Score = 42.4 bits (98), Expect = 0.054
 Identities = 30/131 (22%), Positives = 65/131 (48%), Gaps = 8/131 (6%)
 Frame = +1

Query: 2074 IMCHTVKKLSNVREGEFHFSKTETHCDAPWRISLKKEEACILIYLHCDK---LLSNDENW 2244
            ++ +T++ +SN  + E  FS         W++ + K +  + ++L+C     +L N
Sbjct: 471  LLPYTIENVSNFSDEENRFSDELVWRKMIWKLEVNKSDGFLGVFLYCSLPSGILCNKCQI 530

Query: 2245 SIQVEVQLV-----LGSETGRTLTDKVTHIFNEPEGIHWTKDLTWEDLERDFMVDDSVKI 2409
            S +VE ++V     + SE+G  + +  T    E     +   + W +++ +F++ DS KI
Sbjct: 531  SAKVEYKIVSANGKIHSESG--VANSETKPSMEKPIHSFPNFIKWREMDENFLIADSAKI 588

Query: 2410 EARVKIVKPVE 2442
            E  V+ ++ +E
Sbjct: 589  EVHVQNLEFLE 599



 Score = 40.0 bits (92), Expect = 0.27
 Identities = 36/130 (27%), Positives = 60/130 (45%), Gaps = 6/130 (4%)
 Frame = +1

Query: 7    LSKCEFSMEYTIKNVSKFSAGEIQFSDETIWRNLIWKLKISKLDDFLGVSVYCSQ---TS 177
            L    F+M  T+K++     GE  FS+     +  W++  +K    + + ++C +
Sbjct: 1237 LPSYSFTMLLTLKDIPNVQEGESYFSNTEKHCDAPWRISATKEQSCILIYLHCDKRLCND 1296

Query: 178  NTW-IK-DCQIVGILECKIVSDNGETHEGIRLLNMKPPRKIEGPM-IDFREFLKWDEMKK 348
              W IK + Q+V      +VSD G T      L  K     E P  I + + L W+ ++K
Sbjct: 1297 EHWSIKVEAQLV------LVSDTGRT------LTDKVTHIFERPEGIHWTKDLTWENLEK 1344

Query: 349  NFLTADSVKI 378
            +F+  DSVKI
Sbjct: 1345 DFMVDDSVKI 1354




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