Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F33D4_6
(5142 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|22532932|gb|AAM98028.1| Inositol triphosphate receptor protei... 3388 0.0
gi|14574165|gb|AAK68363.1| Inositol triphosphate receptor protei... 3330 0.0
gi|17541128|ref|NP_501252.1| inositol 1 4 5-Triphosphate Recepto... 3330 0.0
gi|17541126|ref|NP_501253.1| inositol 1 4 5-Triphosphate Recepto... 3308 0.0
gi|25153695|ref|NP_501250.2| inositol 1 4 5-Triphosphate Recepto... 3303 0.0
gi|14574164|gb|AAK68362.1| Inositol triphosphate receptor protei... 3303 0.0
gi|14574166|gb|AAK68364.1| Inositol triphosphate receptor protei... 3300 0.0
gi|25153698|ref|NP_501251.2| inositol 1 4 5-Triphosphate Recepto... 3300 0.0
gi|7500399|pir||T32550 hypothetical protein F33D4.2a - Caenorhab... 3271 0.0
gi|7500401|pir||T32552 hypothetical protein F33D4.2c - Caenorhab... 3271 0.0
gi|39593648|emb|CAE61940.1| Hypothetical protein CBG05938 [Caeno... 2975 0.0
gi|10636263|emb|CAC10528.1| putative inositol 1,4,5-trisphosphat... 2956 0.0
gi|10835023|ref|NP_002213.1| inositol 1,4,5-triphosphate recepto... 1000 0.0
gi|111839|pir||B36579 inositol 1,4,5-triphosphate receptor 2 - r... 999 0.0
gi|6754390|ref|NP_034715.1| inositol 1,4,5-triphosphate receptor... 998 0.0
gi|34857738|ref|XP_342733.1| similar to Inositol 1,4,5-trisphosp... 997 0.0
gi|46107962|gb|AAB04947.2| inositol 1,4,5-trisphosphate receptor... 996 0.0
gi|111838|pir||A36579 inositol 1,4,5-triphosphate receptor 1 - r... 996 0.0
gi|17380349|sp|P29994|IP3R_RAT Inositol 1,4,5-trisphosphate rece... 996 0.0
gi|1362832|pir||A55713 inositol 1,4,5-triphosphate receptor type... 995 0.0
gi|17366467|sp|Q14643|IP3R_HUMAN Inositol 1,4,5-trisphosphate re... 993 0.0
gi|27807313|ref|NP_777266.1| inositol 1,4,5-triphosphate recepto... 980 0.0
gi|7522013|pir||T31431 inositol 1,4,5-trisphosphate receptor, lo... 973 0.0
gi|476810|pir||A40743 IP3 receptor, XIP3R - African clawed frog ... 946 0.0
gi|27805961|ref|NP_776794.1| inositol 1,4,5-triphosphate recepto... 933 0.0
gi|4504793|ref|NP_002214.1| inositol 1,4,5-triphosphate receptor... 932 0.0
gi|13022060|gb|AAK11622.1| IP3 receptor isoform 2 [Rattus norveg... 930 0.0
gi|13591975|ref|NP_112308.1| inositol 1,4,5-triphosphate recepto... 929 0.0
gi|47219802|emb|CAG03429.1| unnamed protein product [Tetraodon n... 929 0.0
gi|18307586|dbj|BAB84088.1| inositol 1,4,5-trisphosphate recepto... 928 0.0
gi|4504795|ref|NP_002215.1| inositol 1,4,5-triphosphate receptor... 923 0.0
gi|17366458|sp|Q14573|IP3T_HUMAN Inositol 1,4,5-trisphosphate re... 921 0.0
gi|6981110|ref|NP_037270.1| inositol 1, 4, 5-triphosphate recept... 918 0.0
gi|27805963|ref|NP_776795.1| inositol 1,4,5-triphosphate recepto... 910 0.0
gi|31217824|ref|XP_316515.1| ENSANGP00000004303 [Anopheles gambi... 868 0.0
gi|50754604|ref|XP_414438.1| PREDICTED: similar to inositol 1,4,... 861 0.0
gi|47227347|emb|CAF96896.1| unnamed protein product [Tetraodon n... 747 0.0
gi|26339686|dbj|BAC33514.1| unnamed protein product [Mus musculus] 658 0.0
gi|47229530|emb|CAG06726.1| unnamed protein product [Tetraodon n... 640 0.0
gi|50760465|ref|XP_418035.1| PREDICTED: similar to Inositol 1,4,... 602 e-170
gi|24644261|ref|NP_730942.1| CG1063-PA [Drosophila melanogaster]... 547 e-154
gi|24644259|ref|NP_730941.1| CG1063-PB [Drosophila melanogaster]... 547 e-154
gi|44888998|sp|P29993|IP3R_DROME Inositol 1,4,5-trisphosphate re... 543 e-152
gi|5689748|emb|CAB51853.1| inositol 1,4,5-trisphosphate receptor... 543 e-152
gi|345496|pir||A43360 inositol 1,4,5-trisphosphate receptor - fr... 543 e-152
gi|48095094|ref|XP_392236.1| similar to CG1063-PB [Apis mellifera] 511 e-143
gi|47212327|emb|CAF91265.1| unnamed protein product [Tetraodon n... 510 e-142
gi|50582469|dbj|BAD32702.1| LIBRA [synthetic construct] 480 e-133
gi|26326875|dbj|BAC27181.1| unnamed protein product [Mus musculus] 468 e-130
gi|26338934|dbj|BAC33138.1| unnamed protein product [Mus musculus] 332 8e-89
gi|27574053|pdb|1N4K|A Chain A, Crystal Structure Of The Inosito... 274 1e-71
gi|21362619|sp||Q9Z329_1 [Segment 1 of 2] Inositol 1,4,5-trispho... 257 2e-66
gi|11245468|gb|AAG33627.1| type I inositol triphosphate receptor... 207 2e-51
gi|3786318|dbj|BAA33961.1| inositol 1,4,5-trisphosphate receptor... 192 7e-47
gi|9910290|ref|NP_064307.1| inositol 1,4,5-triphosphate receptor... 192 7e-47
gi|19388011|gb|AAH25805.1| Itpr5 protein [Mus musculus] 137 2e-30
gi|26335003|dbj|BAC31202.1| unnamed protein product [Mus musculus] 136 6e-30
gi|7441639|pir||PC4441 inositol 1,4,5-triphosphate receptor - ho... 132 1e-28
gi|2809067|dbj|BAA24504.1| inositol 1,4,5-triphosphate recepter ... 132 1e-28
gi|2134400|pir||S66572 ryanodine receptor type 3 - chicken 97 5e-18
gi|46048744|ref|NP_996757.1| ryanodine receptor type 3 [Gallus g... 97 5e-18
gi|401055|sp|P30957|RYR2_RABIT Ryanodine receptor 2 (Cardiac mus... 92 1e-16
gi|1245376|gb|AAA93465.1| cardiac ryanodine receptor 92 1e-16
gi|48094968|ref|XP_392217.1| similar to ENSANGP00000023306 [Apis... 91 2e-16
gi|227245|prf||1617118A ryanodine receptor 91 2e-16
gi|226386|prf||1509336A ryanodine receptor 86 1e-14
gi|134134|sp|P11716|RYR1_RABIT Ryanodine receptor 1 (Skeletal mu... 86 1e-14
gi|39594392|emb|CAE71970.1| Hypothetical protein CBG19042 [Caeno... 84 3e-14
gi|1871447|dbj|BAA08309.1| ryanodine receptor [Caenorhabditis el... 83 8e-14
gi|5823031|gb|AAD53013.1| ryanodine receptor [Expression vector ... 83 8e-14
gi|31231655|ref|XP_318561.1| ENSANGP00000019607 [Anopheles gambi... 81 2e-13
gi|31231666|ref|XP_318563.1| ENSANGP00000023306 [Anopheles gambi... 81 2e-13
gi|31231660|ref|XP_318562.1| ENSANGP00000022873 [Anopheles gambi... 81 2e-13
gi|37704386|ref|NP_001027.2| ryanodine receptor 3 [Homo sapiens] 81 2e-13
gi|2696015|dbj|BAA23795.1| brain ryanodine receptor [Homo sapiens] 81 2e-13
gi|346611|pir||S27272 ryanodine receptor, brain - rabbit >gnl|BL... 81 3e-13
gi|18202506|sp|Q15413|RYR3_HUMAN Ryanodine receptor 3 (Brain-typ... 79 2e-12
gi|9187975|emb|CAB97127.1| inositol 1,4,5-trisphosphate receptor... 78 3e-12
gi|2136552|pir||S68273 inositol 1,4,5-trisphosphate receptor s1 ... 77 3e-12
gi|50405284|ref|YP_054376.1| Inositol 1,4,5-triphosphate recepto... 77 6e-12
gi|29501272|dbj|BAA04647.2| ryanodine receptor beta isoform [Ran... 72 2e-10
gi|1079343|pir||B54161 ryanodine-binding protein beta form - bul... 72 2e-10
gi|1526615|emb|CAA69029.1| ryanodine receptor type 3 [Mustela vi... 70 4e-10
gi|7441641|pir||S74173 ryanodine receptor 3 - Mustela sp 70 4e-10
gi|29165716|gb|AAH43140.1| Similar to ryanodine receptor 2, card... 68 2e-09
gi|13569850|ref|NP_076357.1| ryanodine receptor 2, cardiac; calc... 68 2e-09
gi|4506757|ref|NP_001026.1| ryanodine receptor 2 [Homo sapiens] ... 67 3e-09
gi|1079342|pir||A54161 ryanodine-binding protein alpha form - bu... 65 1e-08
gi|47209126|emb|CAF94369.1| unnamed protein product [Tetraodon n... 65 2e-08
gi|47218152|emb|CAG10072.1| unnamed protein product [Tetraodon n... 64 4e-08
gi|107631|pir||A35041 ryanodine receptor type 1, skeletal muscle... 64 5e-08
gi|10863871|ref|NP_000531.1| ryanodine receptor 1 (skeletal); sa... 64 5e-08
gi|17564924|ref|NP_504753.1| UNCoordinated locomotion UNC-68, Ke... 63 9e-08
gi|47227185|emb|CAG00547.1| unnamed protein product [Tetraodon n... 63 9e-08
gi|15824345|gb|AAL09307.1| skeletal muscle ryanodine receptor [C... 62 1e-07
gi|34855651|ref|XP_341822.1| similar to Ryanodine receptor 2 (Ca... 59 9e-07
gi|1769447|emb|CAA89860.1| skeletal muscle ryanodine receptor [S... 59 9e-07
gi|1937|emb|CAA44674.1| calcium release channel [Sus scrofa] 59 9e-07
gi|2136637|pir||I46646 ryanodine receptor, skeletal muscle - pig... 59 9e-07
gi|164646|gb|AAA31118.1| ryanodine receptor [Sus scrofa] 59 9e-07
gi|1173335|sp|P16960|RYR1_PIG Ryanodine receptor 1 (Skeletal mus... 59 9e-07
gi|50740993|ref|XP_419553.1| PREDICTED: similar to Ryanodine rec... 59 2e-06
gi|45597439|ref|NP_033135.1| ryanodine receptor 1, skeletal musc... 56 1e-05
gi|47224548|emb|CAG03532.1| unnamed protein product [Tetraodon n... 55 2e-05
gi|47221064|emb|CAG12758.1| unnamed protein product [Tetraodon n... 55 2e-05
gi|456984|gb|AAB29457.1| ryanodine receptor, calcium release cha... 53 7e-05
gi|630870|pir||S40450 ryanodine receptor/calcium release channel... 53 7e-05
gi|2160476|dbj|BAA41470.1| ryanodine receptor homologue [Drosoph... 53 7e-05
gi|2160478|dbj|BAA04212.1| ryanodine receptor homologue [Drosoph... 53 7e-05
gi|2160477|dbj|BAA41471.1| ryanodine receptor homologue [Drosoph... 53 7e-05
gi|17352471|ref|NP_476994.1| CG10844-PD [Drosophila melanogaster... 53 7e-05
gi|17352467|ref|NP_476992.1| CG10844-PB [Drosophila melanogaster... 53 7e-05
gi|17352469|ref|NP_476993.1| CG10844-PC [Drosophila melanogaster... 53 7e-05
gi|17352465|ref|NP_476991.1| CG10844-PA [Drosophila melanogaster... 53 7e-05
gi|2108232|gb|AAB58117.1| [Prot=RyR1 isform from fish] Fish RyR1... 50 6e-04
gi|47230258|emb|CAG10672.1| unnamed protein product [Tetraodon n... 50 6e-04
gi|38075727|ref|XP_355386.1| similar to Ryanodine receptor 3 (Br... 49 0.001
gi|34857574|ref|XP_345418.1| similar to Ryanodine receptor 3 (Br... 49 0.001
gi|1935|emb|CAA48318.1| calcium release channel [Sus scrofa] 49 0.001
gi|2136606|pir||I47214 probable brain ryanodine receptor - pig (... 49 0.001
gi|1022321|emb|CAA62975.1| ryanodine receptor [Homo sapiens] 48 0.003
gi|34876273|ref|XP_225491.2| similar to cardiac Ca2+ release cha... 48 0.003
gi|2136485|pir||I47213 cardiac muscle ryanodine receptor - pig (... 48 0.003
gi|13397939|emb|CAC34624.1| skeletal muscle ryanodine receptor [... 47 0.004
gi|562096|gb|AAA60467.1| skeletal muscle ryanodine receptor 47 0.006
gi|2582751|emb|CAA05503.1| ryanodine receptor 3 [Homo sapiens] 46 0.008
gi|18656155|dbj|BAB84714.1| ryanodine receptor [Hemicentrotus pu... 45 0.014
gi|5731972|gb|AAD48899.1| ryanodine receptor type 1 [Rattus norv... 44 0.032
gi|543822|sp|Q01613|APX_XENLA Apical protein (APX) >gnl|BL_ORD_I... 42 0.16
gi|47179465|emb|CAG14775.1| unnamed protein product [Tetraodon n... 33 0.17
gi|23491382|gb|EAA22927.1| hypothetical protein [Plasmodium yoel... 41 0.35
gi|19113921|ref|NP_593009.1| hypothetical coiled-coil protein [S... 40 0.59
gi|39583895|emb|CAE63985.1| Hypothetical protein CBG08577 [Caeno... 40 0.78
gi|50302181|ref|XP_451024.1| unnamed protein product [Kluyveromy... 40 0.78
gi|5852122|emb|CAB55367.1| putative tubulin-tyrosine ligase [Lei... 39 1.0
gi|50539838|ref|NP_001002385.1| zgc:92052 [Danio rerio] >gnl|BL_... 39 1.7
gi|46227114|gb|EAK88064.1| protein with forkhead associated (FHA... 38 2.3
gi|28573169|ref|NP_788597.1| CG32940-PA [Drosophila melanogaster... 38 3.0
gi|112957|sp|P05095|AACT_DICDI Alpha-actinin, non-muscular (F-ac... 38 3.0
gi|28573173|ref|NP_788600.1| CG32940-PD [Drosophila melanogaster... 38 3.0
gi|32398946|emb|CAD98411.1| similarity to rod-like tail of sever... 37 3.9
gi|49067821|ref|XP_398200.1| hypothetical protein UM00585.1 [Ust... 37 3.9
gi|108755|pir||A38318 inositol 1,4,5-triphosphate receptor - bov... 37 3.9
gi|46229305|gb|EAK90154.1| Low complexity hypothetical protein [... 37 3.9
gi|21243825|ref|NP_643407.1| PilL protein [Xanthomonas axonopodi... 37 5.0
gi|50747376|ref|XP_420851.1| PREDICTED: similar to RNA polymeras... 37 5.0
gi|25012112|ref|NP_736507.1| unknown [Streptococcus agalactiae N... 37 5.0
gi|50762120|ref|XP_424943.1| PREDICTED: similar to coiled-coil d... 37 5.0
gi|26189984|emb|CAD34591.1| heme oxygenase [Ceratodon purpureus] 37 5.0
gi|23123961|ref|ZP_00105984.1| COG0642: Signal transduction hist... 37 5.0
gi|11992655|gb|AAG41729.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|16761036|ref|NP_456653.1| mannose-1-phosphate guanylyltransfe... 36 8.6
gi|11992658|gb|AAG41731.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|11992667|gb|AAG41737.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|117277|sp|P26340|MANC_SALTY Mannose-1-phosphate guanylyltrans... 36 8.6
gi|11992661|gb|AAG41733.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|11992664|gb|AAG41735.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|32411845|ref|XP_326403.1| predicted protein [Neurospora crass... 36 8.6
gi|8071634|gb|AAF71823.1| pumilio domain-containing protein PPD1... 36 8.6
gi|11992720|gb|AAG41703.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|11992723|gb|AAG41705.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
gi|39546334|ref|NP_461050.2| mannose-1-phosphate guanylyltransfe... 36 8.6
gi|11992956|gb|AAG41701.1| GDP-mannose pyrophosphorylase [Salmon... 36 8.6
>gi|22532932|gb|AAM98028.1| Inositol triphosphate receptor protein 1,
isoform g [Caenorhabditis elegans]
Length = 1713
Score = 3388 bits (8784), Expect = 0.0
Identities = 1700/1713 (99%), Positives = 1700/1713 (99%)
Frame = +1
Query: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 180
MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS
Sbjct: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 60
Query: 181 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 360
TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD
Sbjct: 61 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 120
Query: 361 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 540
DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA
Sbjct: 121 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 180
Query: 541 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 720
MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF
Sbjct: 181 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 240
Query: 721 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 900
NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK
Sbjct: 241 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 300
Query: 901 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 1080
QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL
Sbjct: 301 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 360
Query: 1081 SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT 1260
SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT
Sbjct: 361 SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT 420
Query: 1261 KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK 1440
KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK
Sbjct: 421 KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK 480
Query: 1441 NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES 1620
NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES
Sbjct: 481 NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES 540
Query: 1621 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 1800
INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP
Sbjct: 541 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 600
Query: 1801 RQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 1980
RQGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ
Sbjct: 601 RQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 660
Query: 1981 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 2160
IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA
Sbjct: 661 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 720
Query: 2161 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 2340
NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD
Sbjct: 721 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 780
Query: 2341 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 2520
YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR
Sbjct: 781 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 840
Query: 2521 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 2700
LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA
Sbjct: 841 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 900
Query: 2701 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 2880
TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE
Sbjct: 901 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 960
Query: 2881 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 3060
GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT
Sbjct: 961 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 1020
Query: 3061 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 3240
KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS
Sbjct: 1021 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 1080
Query: 3241 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 3420
SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS
Sbjct: 1081 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 1140
Query: 3421 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 3600
NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP
Sbjct: 1141 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 1200
Query: 3601 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 3780
RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP
Sbjct: 1201 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 1260
Query: 3781 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 3960
LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL
Sbjct: 1261 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 1320
Query: 3961 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 4140
SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP
Sbjct: 1321 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 1380
Query: 4141 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 4320
EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN
Sbjct: 1381 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 1440
Query: 4321 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 4500
ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH
Sbjct: 1441 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 1500
Query: 4501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 4680
IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK
Sbjct: 1501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 1560
Query: 4681 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 4860
LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK
Sbjct: 1561 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 1620
Query: 4861 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 5040
LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI
Sbjct: 1621 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 1680
Query: 5041 GIGKPVITLVVETQSSKYAQSWSSTLWNIKLYD 5139
GIGKPVITLVVETQSSKYAQSWSSTLWNIKLYD
Sbjct: 1681 GIGKPVITLVVETQSSKYAQSWSSTLWNIKLYD 1713
>gi|14574165|gb|AAK68363.1| Inositol triphosphate receptor protein 1,
isoform c [Caenorhabditis elegans]
Length = 1862
Score = 3330 bits (8633), Expect(2) = 0.0
Identities = 1671/1684 (99%), Positives = 1671/1684 (99%)
Frame = +1
Query: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 180
MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS
Sbjct: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 60
Query: 181 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 360
TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD
Sbjct: 61 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 120
Query: 361 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 540
DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA
Sbjct: 121 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 180
Query: 541 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 720
MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF
Sbjct: 181 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 240
Query: 721 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 900
NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK
Sbjct: 241 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 300
Query: 901 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 1080
QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL
Sbjct: 301 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 360
Query: 1081 SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT 1260
SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT
Sbjct: 361 SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT 420
Query: 1261 KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK 1440
KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK
Sbjct: 421 KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK 480
Query: 1441 NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES 1620
NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES
Sbjct: 481 NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES 540
Query: 1621 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 1800
INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP
Sbjct: 541 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 600
Query: 1801 RQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 1980
RQGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ
Sbjct: 601 RQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 660
Query: 1981 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 2160
IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA
Sbjct: 661 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 720
Query: 2161 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 2340
NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD
Sbjct: 721 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 780
Query: 2341 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 2520
YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR
Sbjct: 781 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 840
Query: 2521 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 2700
LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA
Sbjct: 841 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 900
Query: 2701 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 2880
TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE
Sbjct: 901 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 960
Query: 2881 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 3060
GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT
Sbjct: 961 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 1020
Query: 3061 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 3240
KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS
Sbjct: 1021 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 1080
Query: 3241 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 3420
SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS
Sbjct: 1081 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 1140
Query: 3421 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 3600
NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP
Sbjct: 1141 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 1200
Query: 3601 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 3780
RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP
Sbjct: 1201 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 1260
Query: 3781 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 3960
LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL
Sbjct: 1261 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 1320
Query: 3961 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 4140
SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP
Sbjct: 1321 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 1380
Query: 4141 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 4320
EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN
Sbjct: 1381 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 1440
Query: 4321 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 4500
ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH
Sbjct: 1441 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 1500
Query: 4501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 4680
IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK
Sbjct: 1501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 1560
Query: 4681 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 4860
LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK
Sbjct: 1561 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 1620
Query: 4861 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 5040
LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI
Sbjct: 1621 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 1680
Query: 5041 GIGK 5052
GIGK
Sbjct: 1681 GIGK 1684
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1691 TLNPGHRLYGTSNSMT 1706
>gi|17541128|ref|NP_501252.1| inositol 1 4 5-Triphosphate Receptor,
DEfecation Cycle abnormal DEC-4, Let-23 Fertility
Effector/regulator LFE-1 (325.9 kD) (itr-1)
[Caenorhabditis elegans]
gi|5262805|emb|CAB45860.1| inositol 1,4,5-trisphosphate receptor
[Caenorhabditis elegans]
gi|6175844|gb|AAF05302.1| inositol 1,4,5-trisphosphate receptor
[Caenorhabditis elegans]
gi|14574168|gb|AAK68366.1| Inositol triphosphate receptor protein 1,
isoform f [Caenorhabditis elegans]
Length = 2846
Score = 3330 bits (8633), Expect(2) = 0.0
Identities = 1671/1684 (99%), Positives = 1671/1684 (99%)
Frame = +1
Query: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 180
MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS
Sbjct: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 60
Query: 181 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 360
TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD
Sbjct: 61 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 120
Query: 361 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 540
DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA
Sbjct: 121 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 180
Query: 541 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 720
MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF
Sbjct: 181 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 240
Query: 721 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 900
NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK
Sbjct: 241 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 300
Query: 901 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 1080
QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL
Sbjct: 301 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 360
Query: 1081 SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT 1260
SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT
Sbjct: 361 SAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPT 420
Query: 1261 KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK 1440
KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK
Sbjct: 421 KSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSK 480
Query: 1441 NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES 1620
NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES
Sbjct: 481 NEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKES 540
Query: 1621 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 1800
INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP
Sbjct: 541 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 600
Query: 1801 RQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 1980
RQGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ
Sbjct: 601 RQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 660
Query: 1981 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 2160
IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA
Sbjct: 661 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 720
Query: 2161 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 2340
NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD
Sbjct: 721 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 780
Query: 2341 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 2520
YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR
Sbjct: 781 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 840
Query: 2521 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 2700
LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA
Sbjct: 841 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 900
Query: 2701 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 2880
TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE
Sbjct: 901 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 960
Query: 2881 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 3060
GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT
Sbjct: 961 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 1020
Query: 3061 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 3240
KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS
Sbjct: 1021 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 1080
Query: 3241 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 3420
SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS
Sbjct: 1081 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 1140
Query: 3421 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 3600
NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP
Sbjct: 1141 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 1200
Query: 3601 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 3780
RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP
Sbjct: 1201 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 1260
Query: 3781 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 3960
LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL
Sbjct: 1261 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 1320
Query: 3961 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 4140
SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP
Sbjct: 1321 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 1380
Query: 4141 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 4320
EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN
Sbjct: 1381 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 1440
Query: 4321 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 4500
ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH
Sbjct: 1441 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 1500
Query: 4501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 4680
IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK
Sbjct: 1501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 1560
Query: 4681 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 4860
LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK
Sbjct: 1561 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 1620
Query: 4861 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 5040
LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI
Sbjct: 1621 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 1680
Query: 5041 GIGK 5052
GIGK
Sbjct: 1681 GIGK 1684
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1691 TLNPGHRLYGTSNSMT 1706
>gi|17541126|ref|NP_501253.1| inositol 1 4 5-Triphosphate Receptor,
DEfecation Cycle abnormal DEC-4, Let-23 Fertility
Effector/regulator LFE-1 (327.2 kD) (itr-1)
[Caenorhabditis elegans]
gi|5262811|emb|CAB45863.1| inositol 1,4,5-trisphosphate receptor
[Caenorhabditis elegans]
gi|14574167|gb|AAK68365.1| Inositol triphosphate receptor protein 1,
isoform e [Caenorhabditis elegans]
Length = 2857
Score = 3308 bits (8577), Expect(2) = 0.0
Identities = 1664/1693 (98%), Positives = 1666/1693 (98%), Gaps = 9/1693 (0%)
Frame = +1
Query: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 180
MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS
Sbjct: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 60
Query: 181 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 360
TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD
Sbjct: 61 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 120
Query: 361 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 540
DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA
Sbjct: 121 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 180
Query: 541 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 720
MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF
Sbjct: 181 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 240
Query: 721 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 900
NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK
Sbjct: 241 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 300
Query: 901 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 1080
QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL
Sbjct: 301 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 360
Query: 1081 SAEPSQVQVKPAMNGRRASL---------IYSKTNNPMAMYSDGPNGVTNESTDTTQQNI 1233
SAEPSQVQVKPAMNGR L + +TNNPMAMYSDGPNGVTNESTDTTQQNI
Sbjct: 361 SAEPSQVQVKPAMNGRPPLLSALSQKSRPMLERTNNPMAMYSDGPNGVTNESTDTTQQNI 420
Query: 1234 PSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATE 1413
PSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATE
Sbjct: 421 PSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATE 480
Query: 1414 KQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIK 1593
KQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIK
Sbjct: 481 KQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIK 540
Query: 1594 IGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVF 1773
IGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVF
Sbjct: 541 IGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVF 600
Query: 1774 LLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLA 1953
LLLKAPFLPRQGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLA
Sbjct: 601 LLLKAPFLPRQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLA 660
Query: 1954 EKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLA 2133
EKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLA
Sbjct: 661 EKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLA 720
Query: 2134 DLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKS 2313
DLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKS
Sbjct: 721 DLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKS 780
Query: 2314 NSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLP 2493
NSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLP
Sbjct: 781 NSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLP 840
Query: 2494 YDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIG 2673
YDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIG
Sbjct: 841 YDLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIG 900
Query: 2674 EGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLT 2853
EGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLT
Sbjct: 901 EGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLT 960
Query: 2854 QNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 3033
QNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK
Sbjct: 961 QNLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 1020
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMAS 3213
EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMAS
Sbjct: 1021 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMAS 1080
Query: 3214 ELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLED 3393
ELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLED
Sbjct: 1081 ELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLED 1140
Query: 3394 LKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHD 3573
LKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHD
Sbjct: 1141 LKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHD 1200
Query: 3574 LLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELS 3753
LLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELS
Sbjct: 1201 LLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELS 1260
Query: 3754 DKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHD 3933
DKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHD
Sbjct: 1261 DKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHD 1320
Query: 3934 HDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRN 4113
HDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRN
Sbjct: 1321 HDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRN 1380
Query: 4114 NRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASD 4293
NRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASD
Sbjct: 1381 NRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASD 1440
Query: 4294 EVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELK 4473
EVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELK
Sbjct: 1441 EVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELK 1500
Query: 4474 CASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLE 4653
CASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLE
Sbjct: 1501 CASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLE 1560
Query: 4654 DIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLL 4833
DIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLL
Sbjct: 1561 DIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLL 1620
Query: 4834 ELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQ 5013
ELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQ
Sbjct: 1621 ELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQ 1680
Query: 5014 QAASSAKWIGIGK 5052
QAASSAKWIGIGK
Sbjct: 1681 QAASSAKWIGIGK 1693
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1700 TLNPGHRLYGTSNSMT 1715
>gi|25153695|ref|NP_501250.2| inositol 1 4 5-Triphosphate Receptor,
DEfecation Cycle abnormal DEC-4, Let-23 Fertility
Effector/regulator LFE-1 (330.8 kD) (itr-1)
[Caenorhabditis elegans]
gi|5262807|emb|CAB45861.1| inositol 1,4,5-trisphosphate receptor
[Caenorhabditis elegans]
Length = 2892
Score = 3303 bits (8563), Expect(2) = 0.0
Identities = 1659/1683 (98%), Positives = 1661/1683 (98%)
Frame = +1
Query: 4 DYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST 183
D+D + R MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST
Sbjct: 48 DFDDFEEQIMRKSSMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST 107
Query: 184 LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD 363
LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD
Sbjct: 108 LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD 167
Query: 364 LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM 543
LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM
Sbjct: 168 LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM 227
Query: 544 KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN 723
KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN
Sbjct: 228 KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN 287
Query: 724 LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ 903
LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ
Sbjct: 288 LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ 347
Query: 904 NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS 1083
NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS
Sbjct: 348 NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS 407
Query: 1084 AEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTK 1263
AEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTK
Sbjct: 408 AEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTK 467
Query: 1264 SEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKN 1443
SEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKN
Sbjct: 468 SEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKN 527
Query: 1444 EKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESI 1623
EKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESI
Sbjct: 528 EKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESI 587
Query: 1624 NSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR 1803
NSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR
Sbjct: 588 NSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR 647
Query: 1804 QGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQI 1983
QGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQI
Sbjct: 648 QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQI 707
Query: 1984 GFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEAN 2163
GFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEAN
Sbjct: 708 GFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEAN 767
Query: 2164 KKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDY 2343
KKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDY
Sbjct: 768 KKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDY 827
Query: 2344 YRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRL 2523
YRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRL
Sbjct: 828 YRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRL 887
Query: 2524 MLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLAT 2703
MLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLAT
Sbjct: 888 MLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLAT 947
Query: 2704 VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEG 2883
VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEG
Sbjct: 948 VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEG 1007
Query: 2884 PATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTK 3063
PATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTK
Sbjct: 1008 PATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTK 1067
Query: 3064 LIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSS 3243
LIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSS
Sbjct: 1068 LIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSS 1127
Query: 3244 GHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSN 3423
GHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSN
Sbjct: 1128 GHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSN 1187
Query: 3424 NDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPR 3603
NDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPR
Sbjct: 1188 NDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPR 1247
Query: 3604 AFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPL 3783
AFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPL
Sbjct: 1248 AFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPL 1307
Query: 3784 IRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS 3963
IRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS
Sbjct: 1308 IRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS 1367
Query: 3964 HEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPE 4143
HEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPE
Sbjct: 1368 HEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPE 1427
Query: 4144 ELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNA 4323
ELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNA
Sbjct: 1428 ELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNA 1487
Query: 4324 SFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHI 4503
SFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHI
Sbjct: 1488 SFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHI 1547
Query: 4504 VRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKL 4683
VRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKL
Sbjct: 1548 VRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKL 1607
Query: 4684 TGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKL 4863
TGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKL
Sbjct: 1608 TGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKL 1667
Query: 4864 RGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIG 5043
RGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIG
Sbjct: 1668 RGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIG 1727
Query: 5044 IGK 5052
IGK
Sbjct: 1728 IGK 1730
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1737 TLNPGHRLYGTSNSMT 1752
>gi|14574164|gb|AAK68362.1| Inositol triphosphate receptor protein 1,
isoform a [Caenorhabditis elegans]
Length = 2903
Score = 3303 bits (8563), Expect(2) = 0.0
Identities = 1659/1683 (98%), Positives = 1661/1683 (98%)
Frame = +1
Query: 4 DYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST 183
D+D + R MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST
Sbjct: 48 DFDDFEEQIMRKSSMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST 107
Query: 184 LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD 363
LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD
Sbjct: 108 LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD 167
Query: 364 LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM 543
LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM
Sbjct: 168 LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM 227
Query: 544 KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN 723
KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN
Sbjct: 228 KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN 287
Query: 724 LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ 903
LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ
Sbjct: 288 LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ 347
Query: 904 NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS 1083
NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS
Sbjct: 348 NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS 407
Query: 1084 AEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTK 1263
AEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTK
Sbjct: 408 AEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTK 467
Query: 1264 SEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKN 1443
SEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKN
Sbjct: 468 SEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKN 527
Query: 1444 EKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESI 1623
EKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESI
Sbjct: 528 EKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESI 587
Query: 1624 NSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR 1803
NSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR
Sbjct: 588 NSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPR 647
Query: 1804 QGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQI 1983
QGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQI
Sbjct: 648 QGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQI 707
Query: 1984 GFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEAN 2163
GFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEAN
Sbjct: 708 GFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEAN 767
Query: 2164 KKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDY 2343
KKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDY
Sbjct: 768 KKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDY 827
Query: 2344 YRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRL 2523
YRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRL
Sbjct: 828 YRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRL 887
Query: 2524 MLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLAT 2703
MLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLAT
Sbjct: 888 MLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLAT 947
Query: 2704 VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEG 2883
VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEG
Sbjct: 948 VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEG 1007
Query: 2884 PATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTK 3063
PATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTK
Sbjct: 1008 PATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTK 1067
Query: 3064 LIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSS 3243
LIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSS
Sbjct: 1068 LIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSS 1127
Query: 3244 GHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSN 3423
GHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSN
Sbjct: 1128 GHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSN 1187
Query: 3424 NDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPR 3603
NDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPR
Sbjct: 1188 NDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPR 1247
Query: 3604 AFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPL 3783
AFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPL
Sbjct: 1248 AFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPL 1307
Query: 3784 IRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS 3963
IRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS
Sbjct: 1308 IRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS 1367
Query: 3964 HEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPE 4143
HEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPE
Sbjct: 1368 HEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPE 1427
Query: 4144 ELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNA 4323
ELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNA
Sbjct: 1428 ELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNA 1487
Query: 4324 SFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHI 4503
SFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHI
Sbjct: 1488 SFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHI 1547
Query: 4504 VRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKL 4683
VRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKL
Sbjct: 1548 VRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKL 1607
Query: 4684 TGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKL 4863
TGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKL
Sbjct: 1608 TGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKL 1667
Query: 4864 RGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIG 5043
RGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIG
Sbjct: 1668 RGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIG 1727
Query: 5044 IGK 5052
IGK
Sbjct: 1728 IGK 1730
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1737 TLNPGHRLYGTSNSMT 1752
>gi|14574166|gb|AAK68364.1| Inositol triphosphate receptor protein 1,
isoform d [Caenorhabditis elegans]
Length = 2847
Score = 3300 bits (8556), Expect(2) = 0.0
Identities = 1657/1673 (99%), Positives = 1657/1673 (99%)
Frame = +1
Query: 34 RNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIV 213
R MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIV
Sbjct: 2 RKSSMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIV 61
Query: 214 ELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAAD 393
ELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAAD
Sbjct: 62 ELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAAD 121
Query: 394 KEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNE 573
KEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNE
Sbjct: 122 KEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNE 181
Query: 574 GSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEV 753
GSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEV
Sbjct: 182 GSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEV 241
Query: 754 NCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLR 933
NCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLR
Sbjct: 242 NCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLR 301
Query: 934 MTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKP 1113
MTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKP
Sbjct: 302 MTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKP 361
Query: 1114 AMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANL 1293
AMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANL
Sbjct: 362 AMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANL 421
Query: 1294 LFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICE 1473
LFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICE
Sbjct: 422 LFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICE 481
Query: 1474 KNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC 1653
KNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC
Sbjct: 482 KNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC 541
Query: 1654 ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXX 1833
ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTT
Sbjct: 542 ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLL 601
Query: 1834 XXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTM 2013
DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTM
Sbjct: 602 SSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTM 661
Query: 2014 TAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTS 2193
TAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTS
Sbjct: 662 TAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTS 721
Query: 2194 VLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQ 2373
VLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQ
Sbjct: 722 VLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQ 781
Query: 2374 MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS 2553
MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS
Sbjct: 782 MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS 841
Query: 2554 PMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 2733
PMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN
Sbjct: 842 PMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 901
Query: 2734 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHR 2913
QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHR
Sbjct: 902 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHR 961
Query: 2914 AMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFV 3093
AMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFV
Sbjct: 962 AMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFV 1021
Query: 3094 MDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRD 3273
MDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRD
Sbjct: 1022 MDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRD 1081
Query: 3274 GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID 3453
GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID
Sbjct: 1082 GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID 1141
Query: 3454 RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA 3633
RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA
Sbjct: 1142 RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA 1201
Query: 3634 LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG 3813
LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG
Sbjct: 1202 LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG 1261
Query: 3814 MCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKT 3993
MCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKT
Sbjct: 1262 MCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKT 1321
Query: 3994 NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLI 4173
NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLI
Sbjct: 1322 NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLI 1381
Query: 4174 EHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMK 4353
EHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMK
Sbjct: 1382 EHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMK 1441
Query: 4354 DEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCL 4533
DEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCL
Sbjct: 1442 DEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCL 1501
Query: 4534 VEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEH 4713
VEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEH
Sbjct: 1502 VEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEH 1561
Query: 4714 YICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY 4893
YICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY
Sbjct: 1562 YICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY 1621
Query: 4894 RVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGK 5052
RVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGK
Sbjct: 1622 RVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGK 1674
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1681 TLNPGHRLYGTSNSMT 1696
>gi|25153698|ref|NP_501251.2| inositol 1 4 5-Triphosphate Receptor,
DEfecation Cycle abnormal DEC-4, Let-23 Fertility
Effector/regulator LFE-1 (324.6 kD) (itr-1)
[Caenorhabditis elegans]
gi|5262809|emb|CAB45862.1| inositol 1,4,5-trisphosphate receptor
[Caenorhabditis elegans]
Length = 2836
Score = 3300 bits (8556), Expect(2) = 0.0
Identities = 1657/1673 (99%), Positives = 1657/1673 (99%)
Frame = +1
Query: 34 RNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIV 213
R MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIV
Sbjct: 2 RKSSMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIV 61
Query: 214 ELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAAD 393
ELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAAD
Sbjct: 62 ELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAAD 121
Query: 394 KEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNE 573
KEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNE
Sbjct: 122 KEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNE 181
Query: 574 GSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEV 753
GSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEV
Sbjct: 182 GSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEV 241
Query: 754 NCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLR 933
NCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLR
Sbjct: 242 NCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLR 301
Query: 934 MTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKP 1113
MTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKP
Sbjct: 302 MTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKP 361
Query: 1114 AMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANL 1293
AMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANL
Sbjct: 362 AMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANL 421
Query: 1294 LFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICE 1473
LFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICE
Sbjct: 422 LFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICE 481
Query: 1474 KNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC 1653
KNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC
Sbjct: 482 KNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDC 541
Query: 1654 ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXX 1833
ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTT
Sbjct: 542 ILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTELGPLL 601
Query: 1834 XXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTM 2013
DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTM
Sbjct: 602 SSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTM 661
Query: 2014 TAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTS 2193
TAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTS
Sbjct: 662 TAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTS 721
Query: 2194 VLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQ 2373
VLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQ
Sbjct: 722 VLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLDYYRHQLDLLSQ 781
Query: 2374 MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS 2553
MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS
Sbjct: 782 MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS 841
Query: 2554 PMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 2733
PMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN
Sbjct: 842 PMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 901
Query: 2734 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHR 2913
QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHR
Sbjct: 902 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPSHR 961
Query: 2914 AMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFV 3093
AMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFV
Sbjct: 962 AMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFV 1021
Query: 3094 MDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRD 3273
MDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRD
Sbjct: 1022 MDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRSSGHELHLDGRD 1081
Query: 3274 GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID 3453
GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID
Sbjct: 1082 GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID 1141
Query: 3454 RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA 3633
RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA
Sbjct: 1142 RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA 1201
Query: 3634 LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG 3813
LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG
Sbjct: 1202 LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG 1261
Query: 3814 MCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKT 3993
MCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKT
Sbjct: 1262 MCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKT 1321
Query: 3994 NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLI 4173
NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLI
Sbjct: 1322 NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLI 1381
Query: 4174 EHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMK 4353
EHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMK
Sbjct: 1382 EHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMK 1441
Query: 4354 DEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCL 4533
DEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCL
Sbjct: 1442 DEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCL 1501
Query: 4534 VEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEH 4713
VEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEH
Sbjct: 1502 VEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEH 1561
Query: 4714 YICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY 4893
YICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY
Sbjct: 1562 YICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY 1621
Query: 4894 RVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGK 5052
RVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGK
Sbjct: 1622 RVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWIGIGK 1674
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1681 TLNPGHRLYGTSNSMT 1696
>gi|7500399|pir||T32550 hypothetical protein F33D4.2a - Caenorhabditis
elegans
Length = 2848
Score = 3271 bits (8480), Expect(2) = 0.0
Identities = 1649/1684 (97%), Positives = 1651/1684 (97%), Gaps = 15/1684 (0%)
Frame = +1
Query: 46 MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKD 225
MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKD
Sbjct: 1 MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKD 60
Query: 226 GRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKERE 405
GRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKERE
Sbjct: 61 GRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKERE 120
Query: 406 ENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWF 585
ENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWF
Sbjct: 121 ENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWF 180
Query: 586 IIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLN 765
IIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLN
Sbjct: 181 IIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLN 240
Query: 766 EPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNR 945
EPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNR
Sbjct: 241 EPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNR 300
Query: 946 PSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNG 1125
PSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNG
Sbjct: 301 PSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNG 360
Query: 1126 RRASL---------IYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE 1278
R L + +TNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE
Sbjct: 361 RPPLLSALSQKSRPMLERTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE 420
Query: 1279 EDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWV 1458
EDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWV
Sbjct: 421 EDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWV 480
Query: 1459 KVICEKNRVDKETFALLPVNPDE------VRDLDFANDACKALRNFIKLIKIGQVISKES 1620
KVICEKNRVDKETFALLPVNPDE VRDLDFANDACKALRNFIKLIKIGQVISKES
Sbjct: 481 KVICEKNRVDKETFALLPVNPDEASQSLNVRDLDFANDACKALRNFIKLIKIGQVISKES 540
Query: 1621 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 1800
INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP
Sbjct: 541 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 600
Query: 1801 RQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 1980
RQGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ
Sbjct: 601 RQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 660
Query: 1981 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 2160
IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA
Sbjct: 661 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 720
Query: 2161 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 2340
NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD
Sbjct: 721 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 780
Query: 2341 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 2520
YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR
Sbjct: 781 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 840
Query: 2521 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 2700
LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA
Sbjct: 841 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 900
Query: 2701 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 2880
TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE
Sbjct: 901 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 960
Query: 2881 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 3060
GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT
Sbjct: 961 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 1020
Query: 3061 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 3240
KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS
Sbjct: 1021 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 1080
Query: 3241 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 3420
SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS
Sbjct: 1081 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 1140
Query: 3421 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 3600
NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP
Sbjct: 1141 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 1200
Query: 3601 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 3780
RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP
Sbjct: 1201 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 1260
Query: 3781 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 3960
LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL
Sbjct: 1261 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 1320
Query: 3961 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 4140
SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP
Sbjct: 1321 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 1380
Query: 4141 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 4320
EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN
Sbjct: 1381 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 1440
Query: 4321 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 4500
ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH
Sbjct: 1441 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 1500
Query: 4501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 4680
IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK
Sbjct: 1501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 1560
Query: 4681 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 4860
LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK
Sbjct: 1561 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 1620
Query: 4861 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 5040
LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI
Sbjct: 1621 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 1680
Query: 5041 GIGK 5052
GIGK
Sbjct: 1681 GIGK 1684
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1691 TLNPGHRLYGTSNSMT 1706
>gi|7500401|pir||T32552 hypothetical protein F33D4.2c - Caenorhabditis
elegans
Length = 1966
Score = 3271 bits (8480), Expect(2) = 0.0
Identities = 1649/1684 (97%), Positives = 1651/1684 (97%), Gaps = 15/1684 (0%)
Frame = +1
Query: 46 MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKD 225
MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKD
Sbjct: 1 MALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKD 60
Query: 226 GRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKERE 405
GRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKERE
Sbjct: 61 GRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKERE 120
Query: 406 ENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWF 585
ENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWF
Sbjct: 121 ENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWF 180
Query: 586 IIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLN 765
IIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLN
Sbjct: 181 IIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLN 240
Query: 766 EPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNR 945
EPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNR
Sbjct: 241 EPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNR 300
Query: 946 PSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNG 1125
PSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNG
Sbjct: 301 PSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNG 360
Query: 1126 RRASL---------IYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE 1278
R L + +TNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE
Sbjct: 361 RPPLLSALSQKSRPMLERTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE 420
Query: 1279 EDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWV 1458
EDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWV
Sbjct: 421 EDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWV 480
Query: 1459 KVICEKNRVDKETFALLPVNPDE------VRDLDFANDACKALRNFIKLIKIGQVISKES 1620
KVICEKNRVDKETFALLPVNPDE VRDLDFANDACKALRNFIKLIKIGQVISKES
Sbjct: 481 KVICEKNRVDKETFALLPVNPDEASQSLNVRDLDFANDACKALRNFIKLIKIGQVISKES 540
Query: 1621 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 1800
INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP
Sbjct: 541 INSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLP 600
Query: 1801 RQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 1980
RQGTT DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ
Sbjct: 601 RQGTTELGPLLSSPSELSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQ 660
Query: 1981 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 2160
IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA
Sbjct: 661 IGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEA 720
Query: 2161 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 2340
NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD
Sbjct: 721 NKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHLD 780
Query: 2341 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 2520
YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR
Sbjct: 781 YYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTR 840
Query: 2521 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 2700
LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA
Sbjct: 841 LMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLA 900
Query: 2701 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 2880
TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE
Sbjct: 901 TVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINE 960
Query: 2881 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 3060
GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT
Sbjct: 961 GPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKT 1020
Query: 3061 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 3240
KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS
Sbjct: 1021 KLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIYRS 1080
Query: 3241 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 3420
SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS
Sbjct: 1081 SGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 1140
Query: 3421 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 3600
NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP
Sbjct: 1141 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 1200
Query: 3601 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 3780
RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP
Sbjct: 1201 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 1260
Query: 3781 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 3960
LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL
Sbjct: 1261 LIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITL 1320
Query: 3961 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 4140
SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP
Sbjct: 1321 SHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVP 1380
Query: 4141 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 4320
EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN
Sbjct: 1381 EELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDN 1440
Query: 4321 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 4500
ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH
Sbjct: 1441 ASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDH 1500
Query: 4501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 4680
IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK
Sbjct: 1501 IVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRVEK 1560
Query: 4681 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 4860
LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK
Sbjct: 1561 LTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGK 1620
Query: 4861 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 5040
LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI
Sbjct: 1621 LRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAKWI 1680
Query: 5041 GIGK 5052
GIGK
Sbjct: 1681 GIGK 1684
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1691 TLNPGHRLYGTSNSMT 1706
>gi|39593648|emb|CAE61940.1| Hypothetical protein CBG05938
[Caenorhabditis briggsae]
Length = 2841
Score = 2975 bits (7713), Expect(2) = 0.0
Identities = 1491/1686 (88%), Positives = 1580/1686 (93%), Gaps = 2/1686 (0%)
Frame = +1
Query: 1 MDYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLS 180
M+ DYRRRVL+R IGM LPSRKLTIA+SIDHGNNGNLHIGDIISLYTESS+NQEQRGFLS
Sbjct: 1 MELDYRRRVLDRTIGMNLPSRKLTIASSIDHGNNGNLHIGDIISLYTESSTNQEQRGFLS 60
Query: 181 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 360
TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD
Sbjct: 61 TLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDD 120
Query: 361 DLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 540
DLMNKL+VAA+KEREENE+EFQKTLGN+IQYGSMVQLLHVKSNKYITVQKNSPAKRERNA
Sbjct: 121 DLMNKLRVAAEKEREENEAEFQKTLGNIIQYGSMVQLLHVKSNKYITVQKNSPAKRERNA 180
Query: 541 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSF 720
MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPN+VSTTQ GHVKSQLHLS
Sbjct: 181 MKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNAVSTTQTGHVKSQLHLSGL 240
Query: 721 NLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 900
NLLDHQ+AAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK
Sbjct: 241 NLLDHQTAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK 300
Query: 901 QNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYL 1080
NPP DVVFLRMTNRPSAADATSSRALWEVQVVQ+NAYRGGTAKWNK YRFKHLA+DMYL
Sbjct: 301 TNPPKDVVFLRMTNRPSAADATSSRALWEVQVVQSNAYRGGTAKWNKTYRFKHLASDMYL 360
Query: 1081 SAEPSQVQVKPAMNGRRASLIYSKTNNPMA-MYSDGPNGVTNESTDTTQQNIPSVWVLGP 1257
+ E SQ++ KPAMNGRRASLI+SKT +P+A MYSDGPNG N+++D + P+V L P
Sbjct: 361 TVEESQMKAKPAMNGRRASLIHSKTQSPLASMYSDGPNG-GNDTSDASDG--PTVSFLSP 417
Query: 1258 TKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSS 1437
KS+FPE+D LLF+LDPSTFMKSNKEVPRRSYVRLLH + WVHATNA EKQNLH+S+
Sbjct: 418 KKSDFPEDDIKLLFELDPSTFMKSNKEVPRRSYVRLLHHKTASWVHATNANEKQNLHFSN 477
Query: 1438 KNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKE 1617
KNEKGWVKVICE +RVDKETFALLPVNPDEVRDLDFANDACKALRNFI LIKIG VISKE
Sbjct: 478 KNEKGWVKVICETHRVDKETFALLPVNPDEVRDLDFANDACKALRNFINLIKIGSVISKE 537
Query: 1618 SINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFL 1797
S+NSTTQLLIDCILFVTNSSDHLADPLKI+DFSPSRDRQKLLREQEVL+QVFLLLKAPF
Sbjct: 538 SLNSTTQLLIDCILFVTNSSDHLADPLKITDFSPSRDRQKLLREQEVLHQVFLLLKAPFQ 597
Query: 1798 PRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQE 1977
PRQG+T DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQE
Sbjct: 598 PRQGSTELGPLLGSPADLSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQE 657
Query: 1978 QIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGE 2157
QIGFDLMAEDTMTAVLHNNPKLLEKYVK PHVERFV+LVRNNRQGKFLDYLADLCVCRGE
Sbjct: 658 QIGFDLMAEDTMTAVLHNNPKLLEKYVKAPHVERFVDLVRNNRQGKFLDYLADLCVCRGE 717
Query: 2158 ANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSNSDDAEHL 2337
ANKKIQELICTSVLS KHRDIFMDTK+I+GE+E+GW PNFRKLVDIAEGAKSN DD EHL
Sbjct: 718 ANKKIQELICTSVLSDKHRDIFMDTKVINGEVEIGWDPNFRKLVDIAEGAKSNHDDVEHL 777
Query: 2338 DYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFT 2517
DYYRHQLDLLSQMCQEQQYLAIDPP ER LMNISQQLPAELVLQCMSD RLPYDLRGSFT
Sbjct: 778 DYYRHQLDLLSQMCQEQQYLAIDPPVERGLMNISQQLPAELVLQCMSDTRLPYDLRGSFT 837
Query: 2518 RLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVL 2697
RLMLHLHVVRGSPMSAIRHARLW SIPE+VNVSTYESVSVEAYSDGSRMRIG IAHKVL
Sbjct: 838 RLMLHLHVVRGSPMSAIRHARLWRSIPESVNVSTYESVSVEAYSDGSRMRIGASIAHKVL 897
Query: 2698 ATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN 2877
ATVETYLMGLR+Q +ER SVNSSKLTYEIVNLAK+LAQFNFYSFN+LLQLT+NLLAIIN
Sbjct: 898 ATVETYLMGLRDQPTDERHSVNSSKLTYEIVNLAKSLAQFNFYSFNELLQLTKNLLAIIN 957
Query: 2878 EGPATEQVPSHRAMVNAIRNMSKSMMRGG-NKENSKDLAKTPSVTAEEAGRTKEGRALNV 3054
EGP EQVPSH+AMVN IRNMSKSM+RGG NKENSKDLAKTPS++ ++AGR+KEGRAL V
Sbjct: 958 EGPVPEQVPSHQAMVNVIRNMSKSMLRGGNNKENSKDLAKTPSMSTDDAGRSKEGRALIV 1017
Query: 3055 KTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMASELYDAIY 3234
KTKLIVAEILQFVMDVRRDYRITMALSWFKN FPCDEDGSLMHSASINE+MASELYDAIY
Sbjct: 1018 KTKLIVAEILQFVMDVRRDYRITMALSWFKNEFPCDEDGSLMHSASINEKMASELYDAIY 1077
Query: 3235 RSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLL 3414
SSGHELHLDG+DGQLLLAILLQMTMSDYPPLTSIALKV FRHFTQYQELLEDLKQVQLL
Sbjct: 1078 HSSGHELHLDGKDGQLLLAILLQMTMSDYPPLTSIALKVLFRHFTQYQELLEDLKQVQLL 1137
Query: 3415 VSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLK 3594
VSN+DVENYRQIDRDLFILKNLTEKSELWVHGDR+HS++TKEV++KE+TTE+DL H L
Sbjct: 1138 VSNDDVENYRQIDRDLFILKNLTEKSELWVHGDRNHSVETKEVEDKEKTTEYDLHMHQLN 1197
Query: 3595 SPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIA 3774
+PRAF+S DSM+A++AV+NEHY + +NE LQLLNRLLI DDRND AVALQELSDKAPLIA
Sbjct: 1198 TPRAFESRDSMDAVIAVINEHYSNFKNESLQLLNRLLINDDRNDEAVALQELSDKAPLIA 1257
Query: 3775 YPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLI 3954
YPLIRQMLVRL MCYR G KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDH+MMKLI
Sbjct: 1258 YPLIRQMLVRLKRMCYRDG--KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHEMMKLI 1315
Query: 3955 TLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASN 4134
TLSHEFLR FCK NKENQSRLYKFISYEKDAKEGMLRVET+EEVGTLVAIFRNNRELASN
Sbjct: 1316 TLSHEFLRDFCKANKENQSRLYKFISYEKDAKEGMLRVETVEEVGTLVAIFRNNRELASN 1375
Query: 4135 VPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYV 4314
VPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYV
Sbjct: 1376 VPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYV 1435
Query: 4315 DNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPM 4494
DNASFEELEAMMK EKES+GR ++SR+ LKYHIELVRLLAMCTRGKNGNTELKCASQIPM
Sbjct: 1436 DNASFEELEAMMKQEKESRGRETESRKPLKYHIELVRLLAMCTRGKNGNTELKCASQIPM 1495
Query: 4495 DHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLEDIRSLRV 4674
DHIVRVVT+K CLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVD+ILNNLLEDIRSLR+
Sbjct: 1496 DHIVRVVTSKHCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDNILNNLLEDIRSLRI 1555
Query: 4675 EKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEK 4854
++LT AET LEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELT LE+
Sbjct: 1556 DRLTDAETVALEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTSLER 1615
Query: 4855 GKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASSAK 5034
GKL+ ++SSRNWYRVAECIKRLTKWAEEH I+LPATL GPQMS +VRQKWQ AA+SAK
Sbjct: 1616 GKLKSTRSSRNWYRVAECIKRLTKWAEEH-ISLPATLVGPQMSATATVRQKWQNAATSAK 1674
Query: 5035 WIGIGK 5052
IG+ K
Sbjct: 1675 LIGLNK 1680
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1687 TLNPGHRLYGTSNSMT 1702
>gi|10636263|emb|CAC10528.1| putative inositol 1,4,5-trisphosphate
receptor [Caenorhabditis briggsae]
Length = 2933
Score = 2956 bits (7663), Expect(2) = 0.0
Identities = 1484/1701 (87%), Positives = 1576/1701 (92%), Gaps = 10/1701 (0%)
Frame = +1
Query: 4 DYDYRRRVLERNIGMALPSRKLTIANSIDHGNNGNLHIGDIISLYTESSSNQEQRGFLST 183
D+D + R M LPSRKLTIA+SIDHGNNGNLHIGDIISLYTESS+NQEQRGFLST
Sbjct: 55 DFDDFEEQIMRKSSMNLPSRKLTIASSIDHGNNGNLHIGDIISLYTESSTNQEQRGFLST 114
Query: 184 LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD 363
LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD
Sbjct: 115 LGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDD 174
Query: 364 LMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM 543
LMNKL+VAA+KEREENE+EFQKTLGN+IQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM
Sbjct: 175 LMNKLRVAAEKEREENEAEFQKTLGNIIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAM 234
Query: 544 KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFN 723
KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPN+VSTTQ GHVKSQLHLS N
Sbjct: 235 KVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNAVSTTQTGHVKSQLHLSGLN 294
Query: 724 LLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQ 903
LLDHQ+AAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPK
Sbjct: 295 LLDHQTAAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKT 354
Query: 904 NPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLS 1083
NPP DVVFLRMTNRPSAADATSSRALWEVQVVQ+NAYRGGTAKWNK YRFKHLA+DMYL+
Sbjct: 355 NPPKDVVFLRMTNRPSAADATSSRALWEVQVVQSNAYRGGTAKWNKTYRFKHLASDMYLT 414
Query: 1084 AEPSQVQVKPAMNGR--------RASLIYSKTNNPMA-MYSDGPNGVTNESTDTTQQNIP 1236
E SQ++ KPAMNGR + S I +T +P+A MYSDGPNG N+++D + P
Sbjct: 415 VEESQMKAKPAMNGRPPLLSTLSQKSKILERTQSPLASMYSDGPNG-GNDTSDASDG--P 471
Query: 1237 SVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEK 1416
+V L P KS+FPE+D LLF+LDPSTFMKSNKEVPRRSYVRLLH + WVHATNA EK
Sbjct: 472 TVSFLSPKKSDFPEDDIKLLFELDPSTFMKSNKEVPRRSYVRLLHHKTASWVHATNANEK 531
Query: 1417 QNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKI 1596
QNLH+S+KNEKGWVKVICE +RVDKETFALLPVNPDEVRDLDFANDACK LRNFI LIKI
Sbjct: 532 QNLHFSNKNEKGWVKVICETHRVDKETFALLPVNPDEVRDLDFANDACKXLRNFINLIKI 591
Query: 1597 GQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRDRQKLLREQEVLNQVFL 1776
G VISKES+NSTTQLLIDCILFVTNSSDHLADPLKI+DFSPSRDRQKLLRE+EVL+QVFL
Sbjct: 592 GSVISKESLNSTTQLLIDCILFVTNSSDHLADPLKITDFSPSRDRQKLLREEEVLHQVFL 651
Query: 1777 LLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAE 1956
LLKAPF PRQG+T DSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAE
Sbjct: 652 LLKAPFQPRQGSTELGPLLGSPADLSDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAE 711
Query: 1957 KFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNRQGKFLDYLAD 2136
KFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVK PHVERFV+LVRNNRQGKFLDYLAD
Sbjct: 712 KFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKAPHVERFVDLVRNNRQGKFLDYLAD 771
Query: 2137 LCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGWAPNFRKLVDIAEGAKSN 2316
LCVCRGEANKKIQELICTSVLS KHRDIFMDTK+I+GE+E+GW PNFRKLVDIAEGAKSN
Sbjct: 772 LCVCRGEANKKIQELICTSVLSDKHRDIFMDTKVINGEVEIGWDPNFRKLVDIAEGAKSN 831
Query: 2317 SDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPY 2496
DD EHLDYYRHQLDLLSQMCQEQQYLAIDPP ER LMNISQQLPAELVLQCMSD RLPY
Sbjct: 832 HDDVEHLDYYRHQLDLLSQMCQEQQYLAIDPPVERGLMNISQQLPAELVLQCMSDTRLPY 891
Query: 2497 DLRGSFTRLMLHLHVVRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGE 2676
DLRGSFTRLMLHLHVVRGSPMSAIRHARLW SIPE+VNVSTYESVSVEAYSDGSRMRIG
Sbjct: 892 DLRGSFTRLMLHLHVVRGSPMSAIRHARLWRSIPESVNVSTYESVSVEAYSDGSRMRIGA 951
Query: 2677 GIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQ 2856
IAHKVLATVETYLMGLR+Q +ER SVNSSKLTYEIVNLAK+LAQFNFYSFN+LLQLT+
Sbjct: 952 SIAHKVLATVETYLMGLRDQPTDERHSVNSSKLTYEIVNLAKSLAQFNFYSFNELLQLTK 1011
Query: 2857 NLLAIINEGPATEQVPSHRAMVNAIRNMSKSMMRGG-NKENSKDLAKTPSVTAEEAGRTK 3033
NLLAIINEGP EQVPSH+AMVN IRNMSKSM+RGG NKENSKDLAKTPS++ ++AGR+K
Sbjct: 1012 NLLAIINEGPVPEQVPSHQAMVNVIRNMSKSMLRGGNNKENSKDLAKTPSMSTDDAGRSK 1071
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMAS 3213
EGRAL VKTKLIVAEILQFVMDVRRDYRITMALSWFKN FPCDEDGSLMHSASINE+MAS
Sbjct: 1072 EGRALIVKTKLIVAEILQFVMDVRRDYRITMALSWFKNEFPCDEDGSLMHSASINEKMAS 1131
Query: 3214 ELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLED 3393
ELYDAIY SSGHELHLDG+DGQLLLAILLQMTMSDYPPLTSIALKV FRHFTQYQELLED
Sbjct: 1132 ELYDAIYHSSGHELHLDGKDGQLLLAILLQMTMSDYPPLTSIALKVLFRHFTQYQELLED 1191
Query: 3394 LKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHD 3573
LKQVQLLVSN+DVENYRQIDRDLFILKNLTEKSELWVHGDR+HS++TKEV++KE+TTE+D
Sbjct: 1192 LKQVQLLVSNDDVENYRQIDRDLFILKNLTEKSELWVHGDRNHSVETKEVEDKEKTTEYD 1251
Query: 3574 LLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELS 3753
L H L +PRAF+S DSM+A++AV+NEHY + +NE LQLLNRLLI DDRND AVALQELS
Sbjct: 1252 LHMHQLNTPRAFESRDSMDAVIAVINEHYSNFKNESLQLLNRLLINDDRNDEAVALQELS 1311
Query: 3754 DKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHD 3933
DKAPLIAYPLIRQMLVRL MCYR G KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHD
Sbjct: 1312 DKAPLIAYPLIRQMLVRLKRMCYRDG--KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHD 1369
Query: 3934 HDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRN 4113
H+MMKLITLSHEFLR FCK NKENQSRLYKFISYEKDAKEGMLRVET+EEVGTLVAIFRN
Sbjct: 1370 HEMMKLITLSHEFLRDFCKANKENQSRLYKFISYEKDAKEGMLRVETVEEVGTLVAIFRN 1429
Query: 4114 NRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASD 4293
NRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASD
Sbjct: 1430 NRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASD 1489
Query: 4294 EVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELK 4473
EVRQLYVDNASFEELEAMMK EKES+GR ++SR+ LKYHIELVRLLAMCTRGKNGNTELK
Sbjct: 1490 EVRQLYVDNASFEELEAMMKQEKESRGRETESRKPLKYHIELVRLLAMCTRGKNGNTELK 1549
Query: 4474 CASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLLE 4653
CASQIPMDHIVRVVT+K CLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVD+ILNNLLE
Sbjct: 1550 CASQIPMDHIVRVVTSKHCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDNILNNLLE 1609
Query: 4654 DIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLL 4833
DIRSLR+++LT AET LEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLL
Sbjct: 1610 DIRSLRIDRLTDAETVALEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLL 1669
Query: 4834 ELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQ 5013
ELT LE+GKL+ ++SSRNWYRVAECIKRLTKWAEEH+I+LPATL GPQMS +VRQKWQ
Sbjct: 1670 ELTSLERGKLKSTRSSRNWYRVAECIKRLTKWAEEHSISLPATLVGPQMSATATVRQKWQ 1729
Query: 5014 QAASSAKWIGIGKPVITLVVE 5076
AA+SAK IG+ KPVITLVVE
Sbjct: 1730 NAATSAKLIGLNKPVITLVVE 1750
Score = 38.1 bits (87), Expect(2) = 0.0
Identities = 16/16 (100%), Positives = 16/16 (100%)
Frame = +2
Query: 5093 TLNPGHRLYGTSNSMT 5140
TLNPGHRLYGTSNSMT
Sbjct: 1757 TLNPGHRLYGTSNSMT 1772
>gi|10835023|ref|NP_002213.1| inositol 1,4,5-triphosphate receptor,
type 1 [Homo sapiens]
gi|1085408|pir||S54974 type 1 inositol 1,4,5-trisphosphate receptor -
human
gi|559323|dbj|BAA05065.1| human type 1 inositol 1,4,5-trisphosphate
receptor [Homo sapiens]
Length = 2695
Score = 1000 bits (2586), Expect = 0.0
Identities = 631/1686 (37%), Positives = 924/1686 (54%), Gaps = 67/1686 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAE--PSQVQVKPAMNGRRASLIYSKTNNPMAMYSD 1182
RGG WN +RFKHLAT YL+AE P Q + + + ++YS + P
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEG---- 346
Query: 1183 GPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVR 1362
D + +F+LDP+T + VPR SYVR
Sbjct: 347 --------------------------------NDISSIFELDPTTLRGGDSLVPRNSYVR 374
Query: 1363 LLHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDL 1539
L H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDL
Sbjct: 375 LRHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDL 428
Query: 1540 DFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSP 1719
DFANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P
Sbjct: 429 DFANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKP 487
Query: 1720 SRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCY 1899
+R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 488 NRERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCY 542
Query: 1900 CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVER 2079
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++
Sbjct: 543 RVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDT 602
Query: 2080 FVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------ 2241
FV LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 603 FVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEF 662
Query: 2242 ----------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQ 2355
+ E+ + W + +++ ++A+ AK +D + L YYR+Q
Sbjct: 663 EGVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQ 722
Query: 2356 LDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHL 2535
L+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+
Sbjct: 723 LNLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHM 774
Query: 2536 HVVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVE 2709
HV R ++ +++ARLW IP + + Y+S S S+ I E A + + VE
Sbjct: 775 HVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVE 827
Query: 2710 TYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPA 2889
YL + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++
Sbjct: 828 EYLRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHV 886
Query: 2890 TEQVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGR 3027
T P + N +R+ M++ ++RGG +A P ++A
Sbjct: 887 TTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEP 946
Query: 3028 TKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDED 3168
KE + + TKL + EILQF+++VR DYRI+ L FK F ++
Sbjct: 947 EKED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQE 1005
Query: 3169 GSLMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIA 3342
G +++ E + I+ S L LD G+ L +LL +TM DYPPL S A
Sbjct: 1006 GPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGA 1065
Query: 3343 LKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHH 3522
L++ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1066 LQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG- 1124
Query: 3523 SIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRL 3702
+ +D EH + P+ +S S
Sbjct: 1125 --PDETMDGASGENEHKKTEEGNNKPQKHESTSSYN------------------------ 1158
Query: 3703 LIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNM 3876
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1159 ------------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM 1194
Query: 3877 RVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEG 4056
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+
Sbjct: 1195 GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN-------- 1246
Query: 4057 MLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYD 4236
+ I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V
Sbjct: 1247 LFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEG 1306
Query: 4237 KEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIE 4416
K I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ D L YHI
Sbjct: 1307 KFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD----RMDENSPLMYHIH 1362
Query: 4417 LVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAE 4596
LV LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ E
Sbjct: 1363 LVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVE 1422
Query: 4597 MKDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSA 4773
MK+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1423 MKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFS- 1481
Query: 4774 LQQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNI 4947
+ + F ++L + Y + K+S V CI+ L+ A+ I
Sbjct: 1482 --DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAI 1534
Query: 4948 TLPATL 4965
+P L
Sbjct: 1535 AIPVDL 1540
>gi|111839|pir||B36579 inositol 1,4,5-triphosphate receptor 2 - rat
gi|204674|gb|AAA41357.1| inositol-1,4,5-triphosphate receptor
Length = 2734
Score = 999 bits (2583), Expect = 0.0
Identities = 630/1685 (37%), Positives = 924/1685 (54%), Gaps = 66/1685 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAE--PSQVQVKPAMNGRRASLIYSKTNNPMAMYSD 1182
RGG WN +RFKHLAT YL+AE P Q + + + ++YS + P
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAEVDPDQDASRSRLRNAQEKMVYSLVSVPEG---- 346
Query: 1183 GPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVR 1362
D + +F+LDP+T + VPR SYVR
Sbjct: 347 --------------------------------NDISSIFELDPTTLRGGDSLVPRNSYVR 374
Query: 1363 LLHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDL 1539
L H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDL
Sbjct: 375 LRHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDL 428
Query: 1540 DFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSP 1719
DFANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P
Sbjct: 429 DFANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKP 487
Query: 1720 SRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCY 1899
+R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 488 NRERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCY 542
Query: 1900 CLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVER 2079
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++
Sbjct: 543 RVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDT 602
Query: 2080 FVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------ 2241
FV LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 603 FVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEF 662
Query: 2242 ---------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQL 2358
+ E+ + W + +++ ++A+ AK +D + L YYR+QL
Sbjct: 663 EGVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQL 722
Query: 2359 DLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLH 2538
+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+H
Sbjct: 723 NLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMH 774
Query: 2539 VVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVET 2712
V R ++ +++ARLW IP + + Y+S S S+ I E A + + VE
Sbjct: 775 VDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEE 827
Query: 2713 YLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPAT 2892
YL + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 828 YLRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVT 886
Query: 2893 EQVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRT 3030
P + N +R+ M++ ++RGG +A P ++A
Sbjct: 887 TIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPE 946
Query: 3031 KEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDEDG 3171
KE + + TKL + EILQF+++VR DYRI+ L FK F ++G
Sbjct: 947 KED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEG 1005
Query: 3172 SLMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIAL 3345
+++ E + I+ S L LD G+ L +LL +TM DYPPL S AL
Sbjct: 1006 PSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGAL 1065
Query: 3346 KVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHS 3525
++ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1066 QLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG-- 1123
Query: 3526 IDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLL 3705
+ +D EH + P +S S
Sbjct: 1124 -PDEPMDGASGENEHKKTEEGTSKPLKHESTSSYN------------------------- 1157
Query: 3706 IKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNMR 3879
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1158 -----------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMG 1194
Query: 3880 VYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGM 4059
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+ +
Sbjct: 1195 AHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN--------L 1246
Query: 4060 LRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDK 4239
I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V K
Sbjct: 1247 FLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGK 1306
Query: 4240 EIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIEL 4419
I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ R ++ YHI L
Sbjct: 1307 FIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD---RMDENSPLFMYHIHL 1363
Query: 4420 VRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEM 4599
V LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EM
Sbjct: 1364 VELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEM 1423
Query: 4600 KDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSAL 4776
K+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1424 KEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSVLEKYVTEIVMSIVTTFFSSPFS-- 1481
Query: 4777 QQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNIT 4950
+ + F ++L + Y + K+S V CI+ L+ A+ I
Sbjct: 1482 -DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAIA 1535
Query: 4951 LPATL 4965
+P L
Sbjct: 1536 IPVDL 1540
>gi|6754390|ref|NP_034715.1| inositol 1,4,5-triphosphate receptor 1;
InsP3R type I; Purkinje cell protein 1; opisthotonus;
InsP>3gi|34857738|ref|XP_342733.1| similar to Inositol 1,4,5-trisphosphate
receptor type 1 (Type 1 inositol 1,4,5-trisphosphate
receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform
1) (InsP3R1) (IP-3-R) [Rattus norvegicus]
Length = 2749
Score = 997 bits (2577), Expect = 0.0
Identities = 635/1684 (37%), Positives = 929/1684 (54%), Gaps = 65/1684 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 --------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQLD 2361
+ E+ + W + +++ ++A+ AK +D + L YYR+QL+
Sbjct: 679 GVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLN 738
Query: 2362 LLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHV 2541
L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+HV
Sbjct: 739 LFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHV 790
Query: 2542 VRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETY 2715
R ++ +++ARLW IP + + Y+S S S+ I E A + + VE Y
Sbjct: 791 DRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEEY 843
Query: 2716 LMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATE 2895
L + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 LRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTT 902
Query: 2896 QVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 3033
P + N +R+ M++ ++RGG +A P ++A K
Sbjct: 903 IFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEK 962
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDEDGS 3174
E + + TKL + EILQF+++VR DYRI+ L FK F ++G
Sbjct: 963 ED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGP 1021
Query: 3175 LMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIALK 3348
+++ E + I+ S L LD G+ L +LL +TM DYPPL S AL+
Sbjct: 1022 SNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQ 1081
Query: 3349 VFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSI 3528
+ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1082 LLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG--- 1138
Query: 3529 DTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLI 3708
+ +D EH + P +S S
Sbjct: 1139 PDEPMDGASGENEHKKTEEGTSKPLKHESTSSYN-------------------------- 1172
Query: 3709 KDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNMRV 3882
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1173 ----------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGA 1210
Query: 3883 YEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGML 4062
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+ +
Sbjct: 1211 HAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN--------LF 1262
Query: 4063 RVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKE 4242
I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V K
Sbjct: 1263 LNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKF 1322
Query: 4243 IESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELV 4422
I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ D L YHI LV
Sbjct: 1323 IKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD----RMDENSPLMYHIHLV 1378
Query: 4423 RLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMK 4602
LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EMK
Sbjct: 1379 ELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMK 1438
Query: 4603 DAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQ 4779
+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1439 EIYTSNHMWKLFENFLVDICRACNNTSDRKHADSVLEKYVTEIVMSIVTTFFSSPFS--- 1495
Query: 4780 QAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITL 4953
+ + F ++L + Y + K+S V CI+ L+ A+ I +
Sbjct: 1496 DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAIAI 1550
Query: 4954 PATL 4965
P L
Sbjct: 1551 PVDL 1554
>gi|46107962|gb|AAB04947.2| inositol 1,4,5-trisphosphate receptor type
1 [Homo sapiens]
Length = 2710
Score = 996 bits (2576), Expect = 0.0
Identities = 635/1685 (37%), Positives = 930/1685 (54%), Gaps = 66/1685 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 ---------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQL 2358
+ E+ + W + +++ ++A+ AK +D + L YYR+QL
Sbjct: 679 GVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQL 738
Query: 2359 DLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLH 2538
+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+H
Sbjct: 739 NLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMH 790
Query: 2539 VVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVET 2712
V R ++ +++ARLW IP + + Y+S S S+ I E A + + VE
Sbjct: 791 VDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEE 843
Query: 2713 YLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPAT 2892
YL + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 YLRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVT 902
Query: 2893 EQVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRT 3030
P + N +R+ M++ ++RGG +A P ++A
Sbjct: 903 TIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPE 962
Query: 3031 KEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDEDG 3171
KE + + TKL + EILQF+++VR DYRI+ L FK F ++G
Sbjct: 963 KED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEG 1021
Query: 3172 SLMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIAL 3345
+++ E + I+ S L LD G+ L +LL +TM DYPPL S AL
Sbjct: 1022 PSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGAL 1081
Query: 3346 KVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHS 3525
++ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1082 QLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG-- 1139
Query: 3526 IDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLL 3705
+ +D EH + P+ +S S
Sbjct: 1140 -PDETMDGASGENEHKKTEEGNNKPQKHESTSSYN------------------------- 1173
Query: 3706 IKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNMR 3879
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1174 -----------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMG 1210
Query: 3880 VYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGM 4059
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+ +
Sbjct: 1211 AHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN--------L 1262
Query: 4060 LRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDK 4239
I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V K
Sbjct: 1263 FLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGK 1322
Query: 4240 EIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIEL 4419
I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ D L YHI L
Sbjct: 1323 FIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD----RMDENSPLMYHIHL 1378
Query: 4420 VRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEM 4599
V LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EM
Sbjct: 1379 VELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEM 1438
Query: 4600 KDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSAL 4776
K+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1439 KEIYTSNHMWKLFENFLVDICRACNNTXDRKHADSILEKYVTEIVMSIVTTFFSSPFS-- 1496
Query: 4777 QQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNIT 4950
+ + F ++L + Y + K+S V CI+ L+ A+ I
Sbjct: 1497 -DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAIA 1550
Query: 4951 LPATL 4965
+P L
Sbjct: 1551 IPVDL 1555
>gi|111838|pir||A36579 inositol 1,4,5-triphosphate receptor 1 - rat
gi|204675|gb|AAA41358.1| inositol-1,4,5-triphosphate receptor (alt.,
clone pI16)
Length = 2749
Score = 996 bits (2574), Expect = 0.0
Identities = 634/1684 (37%), Positives = 930/1684 (54%), Gaps = 65/1684 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 --------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQLD 2361
+ E+ + W + +++ ++A+ AK +D + L YYR+QL+
Sbjct: 679 GVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLN 738
Query: 2362 LLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHV 2541
L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+HV
Sbjct: 739 LFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHV 790
Query: 2542 VRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETY 2715
R ++ +++ARLW IP + + Y+S S S+ I E A + + VE Y
Sbjct: 791 DRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEEY 843
Query: 2716 LMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATE 2895
L + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 LRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTT 902
Query: 2896 QVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 3033
P + N +R+ M++ ++RGG +A P ++A K
Sbjct: 903 IFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEK 962
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDEDGS 3174
E + + TKL + EILQF+++VR DYRI+ L FK F ++G
Sbjct: 963 ED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGP 1021
Query: 3175 LMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIALK 3348
+++ E + I+ S L LD G+ L +LL +TM DYPPL S AL+
Sbjct: 1022 SNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQ 1081
Query: 3349 VFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSI 3528
+ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1082 LLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG--- 1138
Query: 3529 DTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLI 3708
+ +D EH + P +S S
Sbjct: 1139 PDEPMDGASGENEHKKTEEGTSKPLKHESTSSYN-------------------------- 1172
Query: 3709 KDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNMRV 3882
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1173 ----------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGA 1210
Query: 3883 YEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGML 4062
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+ +
Sbjct: 1211 HAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN--------LF 1262
Query: 4063 RVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKE 4242
I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V K
Sbjct: 1263 LNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKF 1322
Query: 4243 IESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELV 4422
I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ R ++ YHI LV
Sbjct: 1323 IKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD---RMDENSPLFMYHIHLV 1379
Query: 4423 RLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMK 4602
LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EMK
Sbjct: 1380 ELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMK 1439
Query: 4603 DAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQ 4779
+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1440 EIYTSNHMWKLFENFLVDICRACNNTSDRKHADSVLEKYVTEIVMSIVTTFFSSPFS--- 1496
Query: 4780 QAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITL 4953
+ + F ++L + Y + K+S V CI+ L+ A+ I +
Sbjct: 1497 DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAIAI 1551
Query: 4954 PATL 4965
P L
Sbjct: 1552 PVDL 1555
>gi|17380349|sp|P29994|IP3R_RAT Inositol 1,4,5-trisphosphate receptor
type 1 (Type 1 inositol 1,4,5-trisphosphate receptor)
(Type 1 InsP3 receptor) (IP3 receptor isoform 1)
(InsP3R1) (IP-3-R)
Length = 2750
Score = 996 bits (2574), Expect = 0.0
Identities = 634/1684 (37%), Positives = 930/1684 (54%), Gaps = 65/1684 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPEAGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 --------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQLD 2361
+ E+ + W + +++ ++A+ AK +D + L YYR+QL+
Sbjct: 679 GVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLN 738
Query: 2362 LLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHV 2541
L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+HV
Sbjct: 739 LFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHV 790
Query: 2542 VRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETY 2715
R ++ +++ARLW IP + + Y+S S S+ I E A + + VE Y
Sbjct: 791 DRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEEY 843
Query: 2716 LMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATE 2895
L + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 LRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTT 902
Query: 2896 QVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 3033
P + N +R+ M++ ++RGG +A P ++A K
Sbjct: 903 IFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEK 962
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDEDGS 3174
E + + TKL + EILQF+++VR DYRI+ L FK F ++G
Sbjct: 963 ED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGP 1021
Query: 3175 LMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIALK 3348
+++ E + I+ S L LD G+ L +LL +TM DYPPL S AL+
Sbjct: 1022 SNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQ 1081
Query: 3349 VFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSI 3528
+ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1082 LLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG--- 1138
Query: 3529 DTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLI 3708
+ +D EH + P +S S
Sbjct: 1139 PDEPMDGASGENEHKKTEEGTSKPLKHESTSSYN-------------------------- 1172
Query: 3709 KDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNMRV 3882
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1173 ----------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGA 1210
Query: 3883 YEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGML 4062
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+ +
Sbjct: 1211 HAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN--------LF 1262
Query: 4063 RVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKE 4242
I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V K
Sbjct: 1263 LNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKF 1322
Query: 4243 IESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELV 4422
I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ R ++ YHI LV
Sbjct: 1323 IKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD---RMDENSPLFMYHIHLV 1379
Query: 4423 RLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMK 4602
LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EMK
Sbjct: 1380 ELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMK 1439
Query: 4603 DAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQ 4779
+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1440 EIYTSNHMWKLFENFLVDICRACNNTSDRKHADSVLEKYVTEIVMSIVTTFFSSPFS--- 1496
Query: 4780 QAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITL 4953
+ + F ++L + Y + K+S V CI+ L+ A+ I +
Sbjct: 1497 DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAIAI 1551
Query: 4954 PATL 4965
P L
Sbjct: 1552 PVDL 1555
>gi|1362832|pir||A55713 inositol 1,4,5-triphosphate receptor type 1 -
human
Length = 2713
Score = 995 bits (2572), Expect = 0.0
Identities = 634/1686 (37%), Positives = 930/1686 (54%), Gaps = 67/1686 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE F ++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPVKEDKEAFGIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 ---------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQL 2358
+ E+ + W + +++ ++A+ AK +D + L YYR+QL
Sbjct: 679 GVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQL 738
Query: 2359 DLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLH 2538
+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+H
Sbjct: 739 NLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMH 790
Query: 2539 VVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVET 2712
V R ++ +++ARLW IP + + Y+S S S+ I E A + + VE
Sbjct: 791 VDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEE 843
Query: 2713 YLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPAT 2892
YL + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 YLRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVT 902
Query: 2893 EQVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRT 3030
P + N +R+ M++ ++RGG +A P ++A
Sbjct: 903 TIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPE 962
Query: 3031 KEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVF--------------PCDED 3168
KE + + TKL + EILQF+++VR DYRI+ L FK F ++
Sbjct: 963 KED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFWMKAIPRTSETSSGNSSQE 1021
Query: 3169 GSLMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIA 3342
G +++ E + I+ S L LD G+ L +LL +TM DYPPL S A
Sbjct: 1022 GPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGA 1081
Query: 3343 LKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHH 3522
L++ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1082 LQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG- 1140
Query: 3523 SIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRL 3702
+ +D EH + P+ +S S
Sbjct: 1141 --PDETMDGASGENEHKKTEEGNNKPQKHESTSSYN------------------------ 1174
Query: 3703 LIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNM 3876
Y +++++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1175 ------------------------YRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNM 1210
Query: 3877 RVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEG 4056
+ VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+
Sbjct: 1211 GAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN-------- 1262
Query: 4057 MLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYD 4236
+ I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V
Sbjct: 1263 LFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEG 1322
Query: 4237 KEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIE 4416
K I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ D L YHI
Sbjct: 1323 KFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD----RMDENSPLMYHIH 1378
Query: 4417 LVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAE 4596
LV LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ E
Sbjct: 1379 LVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVE 1438
Query: 4597 MKDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSA 4773
MK+ Y + ++ ++ N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1439 MKEIYTSNHMWKLVENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFS- 1497
Query: 4774 LQQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNI 4947
+ + F ++L + Y + K+S V CI+ L+ A+ I
Sbjct: 1498 --DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAI 1550
Query: 4948 TLPATL 4965
+P L
Sbjct: 1551 AIPVDL 1556
>gi|17366467|sp|Q14643|IP3R_HUMAN Inositol 1,4,5-trisphosphate
receptor type 1 (Type 1 inositol 1,4,5-trisphosphate
receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform
1) (InsP3R1) (IP3R)
Length = 2758
Score = 993 bits (2568), Expect = 0.0
Identities = 635/1694 (37%), Positives = 930/1694 (54%), Gaps = 75/1694 (4%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 ---------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAEHLDYYRHQL 2358
+ E+ + W + +++ ++A+ AK +D + L YYR+QL
Sbjct: 679 GVSSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQL 738
Query: 2359 DLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLH 2538
+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF RLMLH+H
Sbjct: 739 NLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMH 790
Query: 2539 VVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVET 2712
V R ++ +++ARLW IP + + Y+S S S+ I E A + + VE
Sbjct: 791 VDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGASKDEIKERFA-QTMEFVEE 843
Query: 2713 YLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPAT 2892
YL + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 YLRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVT 902
Query: 2893 EQVPSHR----------------AMVNAIRN-------MSKSMMRGGNKENSKDLAKTPS 3003
P + N +R+ M++ ++RGG +A P
Sbjct: 903 TIFPISKMAKGEENKGNNDVEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPE 962
Query: 3004 VTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP--------- 3156
++A KE + + TKL + EILQF+++VR DYRI+ L FK F
Sbjct: 963 GNVKQAEPEKED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSET 1021
Query: 3157 ----CDEDGSLMHSASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSD 3318
++G +++ E + I+ S L LD G+ L +LL +TM D
Sbjct: 1022 SSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHD 1081
Query: 3319 YPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSEL 3498
YPPL S AL++ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSEL
Sbjct: 1082 YPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSEL 1141
Query: 3499 WVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNE 3678
WV+ + + +D EH + P+ +S S
Sbjct: 1142 WVYKGQG---PDETMDGASGENEHKKTEEGNNKPQKHESTSSYN---------------- 1182
Query: 3679 CLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTM 3852
Y +++++L+RL+ +C ++ K
Sbjct: 1183 --------------------------------YRVVKEILIRLSKLCVQESASVRKSRKQ 1210
Query: 3853 NQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFIS 4032
Q+LL+NM + VVLE + +P++K D M +++ L+HEFL++FC N++NQ+ L+K I+
Sbjct: 1211 QQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQALLHKHIN 1270
Query: 4033 YEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELL 4212
+ I E T+ IF NN +L S + E ++ H V IE + RN +++ L
Sbjct: 1271 --------LFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFL 1322
Query: 4213 QALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSR 4392
Q +V K I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ D
Sbjct: 1323 QTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD----RMDEN 1378
Query: 4393 RKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLH 4572
L YHI LV LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L H
Sbjct: 1379 SPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNH 1438
Query: 4573 CYIDTDAEMKDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIK 4749
CY+DT+ EMK+ Y + ++ + N L DI R+ + LE Y+ V ++
Sbjct: 1439 CYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTT 1498
Query: 4750 FFEAPYSALQQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLT 4923
FF +P+S + + F ++L + Y + K+S V CI+ L+
Sbjct: 1499 FFSSPFS---DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLS 1550
Query: 4924 KWAEEHNITLPATL 4965
A+ I +P L
Sbjct: 1551 DVAKSRAIAIPVDL 1564
>gi|27807313|ref|NP_777266.1| inositol 1,4,5-triphosphate receptor,
type 1 [Bos taurus]
gi|17367101|sp|Q9TU34|IP3R_BOVIN Inositol 1,4,5-trisphosphate
receptor type 1 (Type 1 inositol 1,4,5-trisphosphate
receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform
1) (InsP3R1)
gi|6006803|gb|AAF00613.1| inositol 1,4,5-trisphosphate receptor type
I [Bos taurus]
Length = 2709
Score = 980 bits (2534), Expect = 0.0
Identities = 634/1686 (37%), Positives = 926/1686 (54%), Gaps = 67/1686 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K +S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE V P + L + + +P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSVDP---DQDAS 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNKEVPRRSYVRL 1365
+ + ++ SV PE D + +F+LDP+T + VPR SYVRL
Sbjct: 341 RSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDSLVPRNSYVRL 390
Query: 1366 LHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLD 1542
H ++ WVH+T N+ + EK +K+ + DKE FA++PV+P EVRDLD
Sbjct: 391 RHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLD 444
Query: 1543 FANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPS 1722
FANDA K L + ++ G + E S T+LL D + FVT ++ D L++ P+
Sbjct: 445 FANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPN 503
Query: 1723 RDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYC 1902
R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY
Sbjct: 504 RERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAPFRHICRLCYR 558
Query: 1903 LLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERF 2082
+L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ F
Sbjct: 559 VLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTF 618
Query: 2083 VELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII------- 2241
V LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 619 VSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFE 678
Query: 2242 --------------DGEIEVGWAPN-----FRKLVDIAEGAK-SNSDDAEHLDYYRHQLD 2361
+ E+ V W + + + ++A+ AK +D + L YYR+QL+
Sbjct: 679 GVSTGENALEAGEDEEEVWVFWRDSNKEVRSKSVRELAQDAKEGQKEDRDVLGYYRYQLN 738
Query: 2362 LLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHV 2541
L ++MC ++QYLAI+ IS QL +L+L+CMSD LP DLR SF RLMLH+HV
Sbjct: 739 LFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPSDLRASFCRLMLHMHV 790
Query: 2542 VRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETY 2715
R ++ +++ARLW IP + + Y+S S S+ I E A + + VE Y
Sbjct: 791 DRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGTSKDEIKERFA-QTMEFVEEY 843
Query: 2716 LMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATE 2895
L + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++ T
Sbjct: 844 LRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTT 902
Query: 2896 QVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 3033
P + N +R+ M++ ++RGG A P ++A K
Sbjct: 903 IFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPTATAPEGNVKQAEPEK 962
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFP-------------CDEDGS 3174
E + + TKL + EILQF+++VR DYRI+ L FK F ++G
Sbjct: 963 ED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGP 1021
Query: 3175 LMHSASINERMASELYDAIYRSSGH--ELHLDGRDGQLLLAILLQMTMSDYPPLTSIALK 3348
+++ E + I+ S L LD G+ L +LL +TM DYPPL S AL+
Sbjct: 1022 SNVPGALDFEHIEEQAEGIFGGSEETTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQ 1081
Query: 3349 VFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDR--HH 3522
+ FRHF+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ +
Sbjct: 1082 LLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDE 1141
Query: 3523 SIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRL 3702
++D + + + TE + S ++E N
Sbjct: 1142 AMDGASGENEHKKTEEG---------------------------NNKSQQHESTSSYNYR 1174
Query: 3703 LIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNM 3876
++K ++L+RL+ +C ++ K Q+LL+NM
Sbjct: 1175 VVK--------------------------EILIRLSKLCVQESASVRKSRKQQQRLLRNM 1208
Query: 3877 RVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEG 4056
+ VVLE + +P++K D M +++ L+HEFL++FC N NQ+ L+K I+
Sbjct: 1209 GAHAVVLELLQIPYEKAEDTMMQEIMRLAHEFLQNFCAGNHPNQALLHKHIN-------- 1260
Query: 4057 MLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYD 4236
+ I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V
Sbjct: 1261 LFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEG 1320
Query: 4237 KEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIE 4416
K I+ Q+ V E+ + ++V Y D ASF+ L MM+ E++ D L YHI
Sbjct: 1321 KFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERD----RMDENSPLMYHIH 1376
Query: 4417 LVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAE 4596
LV LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+D + E
Sbjct: 1377 LVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDPEVE 1436
Query: 4597 MKDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSA 4773
MK+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P+S
Sbjct: 1437 MKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFS- 1495
Query: 4774 LQQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNI 4947
+ + F ++L + Y + K+S V CI+ L+ A+ I
Sbjct: 1496 --DQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKAS-----VESCIRVLSDVAKSRAI 1548
Query: 4948 TLPATL 4965
+P L
Sbjct: 1549 AIPVDL 1554
>gi|7522013|pir||T31431 inositol 1,4,5-trisphosphate receptor,
localized in plasma membrane - Panulirus argus
gi|3660667|gb|AAC61691.1| inositol 1,4,5-trisphosphate receptor
[Panulirus argus]
Length = 2783
Score = 973 bits (2515), Expect = 0.0
Identities = 636/1743 (36%), Positives = 934/1743 (53%), Gaps = 95/1743 (5%)
Frame = +1
Query: 94 GNNGNLHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFK 273
G+ LH+GDI+SLY E S + GF+STLGLVD RC+V + G +PPKKFRDCLF
Sbjct: 5 GSASFLHMGDIVSLYAEGSVS----GFISTLGLVDARCVVNPEAGDLSTPPKKFRDCLFS 60
Query: 274 VCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQY 453
+CP NRY+AQK W K +G+S D L+N+L AA E+ +NE+E +K +G VI Y
Sbjct: 61 ICPSNRYSAQKQFWKAAKH--SGNSTTDPSLLNRLHDAAKTEKRQNEAESKKLMGTVINY 118
Query: 454 GSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVS 633
G +QLLH+KSNKY+TV K PA E+NAM+VYLD GNEGSWF I P YK GDNV
Sbjct: 119 GITIQLLHLKSNKYLTVNKRLPALLEKNAMRVYLDANGNEGSWFYINPYYKLRNPGDNVV 178
Query: 634 AGNKISLIPNSVSTTQAGHVKSQLHLSS-FNLLDHQSAAEVNCLNEPTEWQVFMFLLFDE 810
G+K+ L P AG QLH+SS +L DH EVN LN T W++ +FL E
Sbjct: 179 VGDKVILSP-----VNAGQ---QLHVSSTHDLRDHPGCKEVNVLNSNTCWKISLFLEHKE 230
Query: 811 NQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEV 990
N + +K GDV+RLFHA+Q+ FLT+D K+ VFLR T R +A ATSS+ALWEV
Sbjct: 231 NLEGVLKGGDVIRLFHAEQEKFLTMDEYKKKQH----VFLRTTGRTTATAATSSKALWEV 286
Query: 991 QVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAE----PSQVQVKPAMNGRRASLIYSKTN 1158
+VVQ + RGG WN +RFKHLAT YL+AE P+ + + +Y +
Sbjct: 287 EVVQHDPSRGGAGHWNSLFRFKHLATGHYLAAEIDDDPTPDPTRTKLRDPNGGPVYQLVS 346
Query: 1159 NPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKE 1338
P++ D +F+L+P+T ++ +
Sbjct: 347 VPLS------------------------------------NDIASIFELEPTTLIRGDSM 370
Query: 1339 VPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVN 1518
VP+ SYVRL H + WVH+T+ + +++ KV C + DKE F+L+PV+
Sbjct: 371 VPQSSYVRLRHLCTSTWVHSTSIPIDKE-----EDKPVMSKVGCAPIKEDKEAFSLVPVH 425
Query: 1519 PDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVT------NSSD 1680
EVRDLDFA+DA + L K ++ G + E S LL+D + F N S+
Sbjct: 426 AKEVRDLDFAHDASEVLAKHAKKLEKGSITQAER-RSLMLLLLDLLYFTAEKEHEQNKSE 484
Query: 1681 HLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDS 1860
LA L++++ P+RDRQKLLREQ +L Q+F +L+APF QG D
Sbjct: 485 SLALALEVTN--PNRDRQKLLREQSILKQIFKILRAPFTETQG---GDGPLLRIDELNDP 539
Query: 1861 RNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPK 2040
R+ +K +F+LCY LL+ +Q YRKNQE +A+ FG +Q+QIG D++AE+T+TA+LHNN K
Sbjct: 540 RHSAYKNIFRLCYRLLRLAQQGYRKNQEHIAQHFGFMQKQIGIDILAEETITALLHNNRK 599
Query: 2041 LLEKYVKTPHVERFVELVRNNRQG---KFLDYLADLCVCRGEANKKIQELICTSVLSSKH 2211
LLE ++ +E FV LVR N +FLDYL LC+ +A + QELIC SV S K+
Sbjct: 600 LLEIHITATEIETFVGLVRKNMHKWDWRFLDYLKVLCISNNQAIPRTQELICKSVFSEKN 659
Query: 2212 RDIFMDTKIIDGEIEV-----GWAPNF------------------RKLVDIAEGAKSNSD 2322
+DI ++T++++ +IEV G P + +V++A A++ SD
Sbjct: 660 KDILIETRLVEEDIEVEVNVEGSCPMLAIERDEEVVLTWNNGECSKSIVELASRAQNLSD 719
Query: 2323 -----DAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNR 2487
D L+YYRH LDL S MC ++QYLAI P +S L L+L+CM +
Sbjct: 720 SDGGEDRLILEYYRHMLDLFSNMCLDRQYLAIRP--------LSPLLKINLMLKCMEEET 771
Query: 2488 LPYDLRGSFTRLMLHLHV--VRGSPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSR 2661
L YDLR +F RLMLH+HV ++ +++ARLW I +++++ Y+ + ++ +
Sbjct: 772 LAYDLRAAFCRLMLHMHVDCEPQEMVTPVKYARLWSEIQPHMSIADYDKHAAMHSTEAAE 831
Query: 2662 MRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDL 2841
+ V+ VE YL + ++ M +KLT+E+V LA+ L F FYSFNDL
Sbjct: 832 TTFKD-----VIVFVEEYLCNVVDK-MWSFSDCEQNKLTFEVVKLARYLIYFGFYSFNDL 885
Query: 2842 LQLTQNLLAIINEGPATEQ------VPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTP- 3000
L+LT+ LL+I++ T+ +P A +A + KS+ G + L T
Sbjct: 886 LRLTKTLLSILDYSFDTDSKYFSNSIPQGTA--SAKGGVIKSLGDMGAVVTNLALGTTRM 943
Query: 3001 -------SVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPC 3159
S ++ G T++ L + TKL + EIL+F+++VR DYRI+ LS FK
Sbjct: 944 GPRLGGGSSPKKKVGATEKEDTLVMDTKLKIIEILEFILNVRLDYRISCLLSIFKK--ES 1001
Query: 3160 DEDGSLMHSASINERM-----------ASELYD----------------AIYRSSGHE-- 3252
DE+ S + I++ + A ++D ++ SS E
Sbjct: 1002 DENPSSLTGEGISQGLKNKNVENIWAQAQSIFDETSGLGLVWSSSQRKPSLQTSSCEENS 1061
Query: 3253 -LHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNND 3429
L LDG G+ L +LL +TM +YPPL S +L++ FRHF+Q QE+L++ KQVQLLV + D
Sbjct: 1062 SLDLDGEGGKKFLRVLLHLTMHEYPPLVSRSLQLLFRHFSQRQEVLQNFKQVQLLVQDGD 1121
Query: 3430 VENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAF 3609
VE+Y+QI D L+NL EKSELWV+ R D +K++ + D D L P+
Sbjct: 1122 VESYKQIKEDSDDLRNLVEKSELWVYKSRSTDEDGGGTKKKKKKNKDDDEDDALSKPKKP 1181
Query: 3610 DSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIA--YPL 3783
+ L D+ ++A+ L P A Y
Sbjct: 1182 PAPK---------------------------LTAQDKQESAIDLGLGPPLEPEQADNYKR 1214
Query: 3784 IRQMLVRLTGMCYRK---GDPKPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLI 3954
I+Q+LVR+ +C + G+ P Q+LL+NM ++ VVLE + +P+D+K D M +LI
Sbjct: 1215 IQQILVRMNKLCVTQSSHGNLSPKRNEQRLLRNMGIHSVVLELLQIPYDRKEDKRMNELI 1274
Query: 3955 TLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASN 4134
L+H+FL++FC ++ NQ+ LYK S + G+L +T+ A+F++N L S
Sbjct: 1275 ELAHQFLQNFCLGDRANQALLYK--SIDLFLNPGLLEAKTV------CAVFKDNSHLCSE 1326
Query: 4135 VPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYV 4314
V E +I H + IE + R+ +L+ LQ +V + + Q+ V E+ A ++V Y
Sbjct: 1327 VSERVIQHFIHCIETHGRHVQYLKFLQTIVKAEGQFLRRSQDIVMQELVNAGEDVLVFYN 1386
Query: 4315 DNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPM 4494
+ ASF MMK ++ D L+YHIELV+LLA CT GKN +TE+KC S +P+
Sbjct: 1387 ERASFNMFIEMMKADRNRM--DFDDSSPLRYHIELVKLLACCTEGKNASTEIKCHSLLPL 1444
Query: 4495 DHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNN--LLEDIRSL 4668
D IV +V K C+ EVK Y+ L HCYIDT+ EMK+ Y + ++ + L++ R
Sbjct: 1445 DDIVAMVEHKDCIPEVKEAYINFLNHCYIDTEVEMKEIYNSHHIWSLFEKSFLVDMGRVA 1504
Query: 4669 RVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYL 4848
LE+Y+ +++ ++ FF +P+S Q + + F + LL Y
Sbjct: 1505 TAPPDRRHADKALENYVINSLMTIITTFFNSPFSDQSQT---IQTRQPVFVQ-LLHAVYR 1560
Query: 4849 EKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATLAGPQMSGQTSVRQKWQQAASS 5028
+ G + V CIK LT+ A +HNI++P L +S S R ++
Sbjct: 1561 VSQAVMGHQR----VNVENCIKTLTEVARKHNISIPVDLEAQVVS--MSQRTTSIMTRTA 1614
Query: 5029 AKW 5037
+KW
Sbjct: 1615 SKW 1617
>gi|476810|pir||A40743 IP3 receptor, XIP3R - African clawed frog
gi|464220|dbj|BAA03304.1| inositol 1,4,5-triphosphate receptor
[Xenopus laevis]
Length = 2693
Score = 946 bits (2446), Expect = 0.0
Identities = 621/1685 (36%), Positives = 918/1685 (53%), Gaps = 66/1685 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LH+GDI+SLY E S N GF++TLGLVDDR +V+ G +PPKKFRDCLF++CP+N
Sbjct: 9 LHVGDIVSLYAEGSVN----GFINTLGLVDDRSVVQPDAGDLNNPPKKFRDCLFRLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K S D L+NKL AAD E+++NE+E +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGASSTTDTVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IGD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L D+ EVN +N T W++ +F+ + +N+ + +
Sbjct: 183 VLNP-----VNAG---QPLHASSQQLSDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VVQ +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKALWEVEVVQHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE + +P R ++ K + +G
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGHYLAAE---IDAEPDAGNARMQVVPEKMMCTLISVPEG- 346
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
D + +F+LDP+T + VPR SYVRL
Sbjct: 347 ------------------------------NDISSIFELDPTTLRGGDSLVPRNSYVRLR 376
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ WVH+TN+ ++ + + +++ + DKE FA++PV+P EVRDLDFA
Sbjct: 377 HLCTNTWVHSTNSPIDKD-----EEKPVMLRIGTSPVKEDKEAFAIVPVSPAEVRDLDFA 431
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA K L + ++ G + E + T+LL + + FVT + D L++ P+R+
Sbjct: 432 NDASKVLSSIAGKLEKGTITQNER-RAVTKLLEELVYFVTGLVNSGHDILEVLVNKPNRE 490
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY +L
Sbjct: 491 RQKLMREQNILKQIFKLLQAPF-----TDSGDGPMLRLEELGDQRHAPFRHICRLCYRVL 545
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ FV
Sbjct: 546 RHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVS 605
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII--------- 2241
LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK++
Sbjct: 606 LVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPANADILIETKLVLSRFEFEGV 665
Query: 2242 ---DGEIEVG---------WAPN-----FRKLVDIAEGAK-SNSDDAEHLDYYRHQLDLL 2367
+ +E G W + R + ++A+ AK +D + L+YYR+QL+L
Sbjct: 666 ASGESSLEAGEDEEEVWLFWKASNKEIRSRSVRELAQDAKEGQKEDQDVLNYYRYQLNLF 725
Query: 2368 SQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVR 2547
++MC ++QYLAI+ IS QL +L+L+CMSD LP+DLR SF RLMLH+HV R
Sbjct: 726 ARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPFDLRASFCRLMLHMHVDR 777
Query: 2548 G--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLM 2721
++ +++ARLW IP + + Y+S S SR I E A + + VE YL
Sbjct: 778 DPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGTSRDDIKERFA-QTMEFVEEYLR 830
Query: 2722 GLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQV 2901
+ Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++
Sbjct: 831 DVVGQRFPFADK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAIVDCVHLIANF 889
Query: 2902 PS--------HRAMVNAIRN-------MSKSMMRGGNKENSKDLAKTPSVTAEEAGRTKE 3036
PS + N +R+ M++ ++RGG +A P T + ++
Sbjct: 890 PSGKLGKGEESKGGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMA-APEGTIKAQREPEK 948
Query: 3037 GRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHS--------AS 3192
L + TKL + EILQF+++VR DYRI+ L FK+ F S+ S +
Sbjct: 949 EDILVMDTKLKIIEILQFILNVRLDYRISCLLCIFKSEFDESNAQSVEGSTEAITVVPGT 1008
Query: 3193 INERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHF 3366
++ E + I+ S L LD G+ L +LL +TM DYPPL S AL + FRHF
Sbjct: 1009 LDFEHIEEQAEGIFGGSEENTPLDLDDDGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHF 1068
Query: 3367 TQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVH-GDRHHSIDTKEV 3543
+Q QE+L+ KQVQLLV++ DV+NY+QI +DL L+++ EKSELWV+ G + +
Sbjct: 1069 SQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGSGPEEVTAAQA 1128
Query: 3544 DEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRN 3723
++ ++P +S + +Y ++ E L L++L ++++
Sbjct: 1129 GGADKG----------ETPGKAKKSESTSSY------NYRVVK-EILLRLSKLCVQENTT 1171
Query: 3724 DAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEF 3903
Q+ + A+ ++ ++L + Y K + DT Q+++K
Sbjct: 1172 GRRNRKQQQRLLRNMGAHSVVLELL----QIPYEKTE---DTRMQEIMK----------- 1213
Query: 3904 ISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE 4083
++HEFL++FC N++NQ+ L+K I+ + I E
Sbjct: 1214 ------------------IAHEFLQNFCAGNQQNQALLHKHIN--------LFLTPGILE 1247
Query: 4084 VGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEK 4263
T+ IF NN +L S + E ++ H IE + RN +++ LQ +V + I+ Q+
Sbjct: 1248 AVTMQHIFMNNFQLCSEINERVVQHFAHCIETHGRNVQYIKFLQTIVKAEGRYIKKCQDI 1307
Query: 4264 VANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCT 4443
V E+ + ++V Y D ASF+ L MM+ E+E D L YHI LV LLA+CT
Sbjct: 1308 VMAELVNSGEDVLVFYNDRASFQTLVQMMRSERE----RMDENSPLMYHIHLVELLAVCT 1363
Query: 4444 RGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY 4623
GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EMK+ Y + +
Sbjct: 1364 EGKNVYTEIKCNSLLPLDDIVRVVTHEDCVPEVKIAYINFLNHCYVDTEVEMKEIYTSNH 1423
Query: 4624 VDHILNNLLEDIRSLRVEKLTGAE---TATLEHYICHTVTEVLIKFFEAPYS----ALQQ 4782
+ + N L DI RV T LE Y+ V ++ FF +P+S LQ
Sbjct: 1424 MWKLFENFLVDI--CRVCNSTSDRKHADIVLERYVTEIVMSIVNTFFSSPFSDQSTTLQA 1481
Query: 4783 AKVDVHHHKK--TFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNIT 4950
+K+ V H + F ++L + Y L K+S V CI+ L+ A+ I
Sbjct: 1482 SKLAVVHQTRQPVFVQLLQAIFRVYHCNWLLPSQKAS-----VESCIRVLSDVAKSRTIA 1536
Query: 4951 LPATL 4965
+P L
Sbjct: 1537 IPVDL 1541
>gi|27805961|ref|NP_776794.1| inositol 1,4,5-triphosphate receptor,
type 2 [Bos taurus]
gi|17432546|gb|AAL39077.1| inositol 1,4,5-trisphosphate receptor type
2 [Bos taurus]
Length = 2701
Score = 933 bits (2411), Expect = 0.0
Identities = 606/1674 (36%), Positives = 901/1674 (53%), Gaps = 55/1674 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
L+IGDI+SLY E S N GF++TLGLVDDRC+V + G +PPKKFRDCLFKVCP+N
Sbjct: 9 LYIGDIVSLYAEGSVN----GFINTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + L+ KL+ AA+ E+++NESE +K LG +++Y +++Q
Sbjct: 65 RYSAQKQYWKAKQAKQGNHT--EAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I P +K + GDN+ G K+
Sbjct: 123 LLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGGKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L+P AG LH S+ LLD+ EVN +N T W++ +F+ + +++ +
Sbjct: 183 VLMP-----VNAGQ---PLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ +FLR T R SA ATSS+ALWE++VV +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEYEKKQH----IFLRTTLRQSATSATSSKALWEIEVVHHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG +WN +RFKHLAT YL+AE + P Y N DG
Sbjct: 291 PCRGGAGQWNSLFRFKHLATGNYLAAE-----LNPD---------YRDAQNEGKNVRDGD 336
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
+ + ++ ++ S D LF+LD +T +++ VPR SYVRL
Sbjct: 337 LPASKKKRQAGEK------IMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ WV +T+ + + +K+ + + DKE FA++ V P EVRDLDFA
Sbjct: 391 HLCTNTWVTSTSIPID-----TDEERPVMLKIGTCQTKEDKEAFAIVSVPPSEVRDLDFA 445
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA K L +K ++ G + E T+LL D I FV + ++ D L + P+R+
Sbjct: 446 NDANKVLATTVKKLENGTITQNER-RFVTKLLEDLIFFVADVPNNGQDVLDVLITKPNRE 504
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ +L QVF +LKAPF + G D R +K M +LCY +L
Sbjct: 505 RQKLMREQNILAQVFGILKAPFKEKAGE----GSMLRLEDLGDQRYAPYKYMLRLCYRVL 560
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
+SQ YRKNQE++A+ F +Q QIG+D++AEDT+TA+LHNN KLLEK++ +E FV
Sbjct: 561 GHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVS 620
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII--------- 2241
L+R NR+ +FLDYL+DLCV A QELIC +LS + DI + TK++
Sbjct: 621 LLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKLVSMQGDNPME 680
Query: 2242 ---------DGEIEVGW-----APNFRKLVDIAEGAKSNSD-DAEHLDYYRHQLDLLSQM 2376
+ E+ + W P+ + + +A+ AK + D E L YYR+QL+L ++M
Sbjct: 681 SAILSDDIDEEEVWLYWIDSNKEPHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARM 740
Query: 2377 CQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP 2556
C ++QYLAI+ IS QL +L+L+CMSD LP+DLR SF RLMLH+HV R
Sbjct: 741 CLDRQYLAIN--------QISTQLSVDLILRCMSDESLPFDLRASFCRLMLHMHVDRDPQ 792
Query: 2557 MSA--IRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLR 2730
S +R+ARLW IP + + Y+S+ +D SR + A + VE YL +
Sbjct: 793 ESVVPVRYARLWTEIPTKITIHEYDSI-----TDSSRNDMKRKFA-LTMEFVEEYLKEVV 846
Query: 2731 NQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN--EGPATEQVP 2904
NQ +KLT+E+V+LA+ L F FYSF++LL+LT+ LLAI++ + P +
Sbjct: 847 NQPFPFGDK-EKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFE 905
Query: 2905 SHRAMVNAIRNMSKSMMRGGNKENSKDLAK-----------TPSVTAEEAGRTKEGRALN 3051
+ N+ +++ G L++ PS+ + G + +
Sbjct: 906 RLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDIQPSLHPSKQGSPTDHEDVT 965
Query: 3052 V-KTKLIVAEILQFVMDVRRDYRITMALSWFKNVF-------PCDEDGS---LMHSA--- 3189
V TKL + EILQF++ VR DY I+ LS +K F +GS L+ SA
Sbjct: 966 VMDTKLKIIEILQFILSVRLDYGISYMLSIYKKEFGENNGNAEMSTNGSPDTLLPSAIVP 1025
Query: 3190 SINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFT 3369
I+E A R + + LD G+ L +L+ + M DYPPL S AL++ F+HF+
Sbjct: 1026 DIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYPPLLSGALQLLFKHFS 1085
Query: 3370 QYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDE 3549
Q E+L+ KQVQLLVSN DV+NY+QI DL L+ EKSELWV ++ S + E+ E
Sbjct: 1086 QRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWV--EKSSSYENGEMGE 1143
Query: 3550 KE-RTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRND 3726
+ + E + D ++ SP ++D
Sbjct: 1144 NQVKGGEEPIEDSNILSP-----------------------------------VQDGTKK 1168
Query: 3727 AAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFI 3906
+ + ++ Y +++++L+RL+ +C + + K +Q+LLKNM + VVL+ +
Sbjct: 1169 PQIDSNKSNN------YRIVKEILIRLSKLCVQ--NKKCRNQHQRLLKNMGAHSVVLDLL 1220
Query: 3907 SVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEV 4086
+P++ K+D M +++ L+H FL++FC+ N +NQ L+K ++ G+L ET+
Sbjct: 1221 QIPYE-KNDEKMNEVMNLAHTFLQNFCRGNPQNQVLLHKHLNL--FLTPGLLEAETMRH- 1276
Query: 4087 GTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKV 4266
IF NN L + + E ++ H V IE + R+ +L LQ +V K ++ Q+ V
Sbjct: 1277 -----IFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMV 1331
Query: 4267 ANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTR 4446
E+ ++V Y D ASF L MM E++ D L YHI LV LLA CT
Sbjct: 1332 MTELINGGEDVLIFYNDRASFPILLHMMCSERD----RGDESGPLAYHITLVELLAACTE 1387
Query: 4447 GKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYV 4626
GKN TE+KC S +P+D IVRVVT C+ EVK Y+ + HCY+DT+ EMK+ Y + ++
Sbjct: 1388 GKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHI 1447
Query: 4627 DHILNNLLEDIRSLRVEKLTGAETAT-LEHYICHTVTEVLIKFFEAPYSALQQAKVDVHH 4803
+ N L D+ + T LE + ++ ++ FF +P+S +
Sbjct: 1448 WKLFENFLVDMARVCNTTTDRKHADTFLEKCVTESIMNIVSGFFNSPFS---DNSTSLQT 1504
Query: 4804 HKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATL 4965
H+ F ++L + + V CI+ L + A+ I +P L
Sbjct: 1505 HQPVFIQLLQSAFRIYNCTWPNPAQKAS---VESCIRTLAEVAKNRGIAIPVDL 1555
>gi|4504793|ref|NP_002214.1| inositol 1,4,5-triphosphate receptor,
type 2 [Homo sapiens]
gi|2833252|sp|Q14571|IP3S_HUMAN Inositol 1,4,5-trisphosphate receptor
type 2 (Type 2 inositol 1,4,5-trisphosphate receptor)
(Type 2 InsP3 receptor) (IP3 receptor isoform 2)
(InsP3R2)
gi|450469|dbj|BAA05384.1| type 2 inositol 1,4,5-trisphosphate
receptor [Homo sapiens]
Length = 2701
Score = 932 bits (2409), Expect = 0.0
Identities = 605/1675 (36%), Positives = 901/1675 (53%), Gaps = 56/1675 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
L+IGDI+SLY E S N GF+STLGLVDDRC+V + G +PPKKFRDCLFKVCP+N
Sbjct: 9 LYIGDIVSLYAEGSVN----GFISTLGLVDDRCVVHPEAGDLANPPKKFRDCLFKVCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + L+ KL+ AA+ E+++NESE +K LG +++Y +++Q
Sbjct: 65 RYSAQKQYWKAKQAKQGNHT--EAALLKKLQHAAELEQKQNESENKKLLGEIVKYSNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I P +K + GDN+ G+K+
Sbjct: 123 LLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L+P AG LH S+ LLD+ EVN +N T W++ +F+ + +++ +
Sbjct: 183 VLMP-----VNAGQ---PLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKYSSYREDVL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ +FLR T R SA ATSS+ALWE++VV +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDEYEKKQH----IFLRTTLRQSATSATSSKALWEIEVVHHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG +WN +RFKHLAT YL+AE + P Y N DG
Sbjct: 291 PCRGGAGQWNSLFRFKHLATGNYLAAE-----LNPD---------YRDAQNEGKNVRDGV 336
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
+ + ++ ++ S D LF+LD +T +++ VPR SYVRL
Sbjct: 337 PPTSKKKRQAGEK------IMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ WV +T+ + + +K+ + + DKE FA++ V EVRDLDFA
Sbjct: 391 HLCTNTWVTSTSIPID-----TDEERPVMLKIGTCQTKEDKEAFAIVSVPLSEVRDLDFA 445
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA K L +K ++ G + E T+LL D I FV + ++ + L + P+R+
Sbjct: 446 NDANKVLATTVKKLENGTITQNER-RFVTKLLEDLIFFVADVPNNGQEVLDVVITKPNRE 504
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ +L QVF +LKAPF + G D R +K M +LCY +L
Sbjct: 505 RQKLMREQNILAQVFGILKAPFKEKAGE----GSMLRLEDLGDQRYAPYKYMLRLCYRVL 560
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
++SQ YRKNQE++A+ F +Q QIG+D++AEDT+T +LHNN KLLEK++ +E FV
Sbjct: 561 RHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITPLLHNNRKLLEKHITAKEIETFVS 620
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII--------- 2241
L+R NR+ +FLDYL+DLCV A QELIC +LS + DI + TK++
Sbjct: 621 LLRRNREPRFLDYLSDLCVSNTTAIPVTQELICKFMLSPGNADILIQTKVVSMQADNPME 680
Query: 2242 ---------DGEIEVGW-----APNFRKLVDIAEGAKSNSD-DAEHLDYYRHQLDLLSQM 2376
D E+ + W P+ + + +A+ AK + D E L YYR+QL+L ++M
Sbjct: 681 SSILSDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAKEGTKADLEVLTYYRYQLNLFARM 740
Query: 2377 CQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP 2556
C ++QYLAI+ IS QL +L+L+C+SD LP+DLR SF RLMLH+HV R
Sbjct: 741 CLDRQYLAIN--------QISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQ 792
Query: 2557 MSA--IRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLR 2730
S +R+ARLW IP + + Y+S+ +D SR + A + VE YL +
Sbjct: 793 ESVVPVRYARLWTEIPTKITIHEYDSI-----TDSSRNDMKRKFA-LTMEFVEEYLKEVV 846
Query: 2731 NQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN--EGPATEQVP 2904
NQ +KLT+E+V+LA+ L F FYSF++LL+LT+ LLAI++ + P +
Sbjct: 847 NQPFPFGDK-EKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFE 905
Query: 2905 SHRAMVNAIRNMSKSMMRGGNKENSKDLAK-----------TPSVTAEEAGRTKEGRALN 3051
+ N+ +++ G L++ PS+ + G E +
Sbjct: 906 RLSKFQDGGNNVMRTIHGVGEMMTQMVLSRGSIFPMSVPDVPPSIHPSKQGSPTEHEDVT 965
Query: 3052 V-KTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDG----------SLMHSA--- 3189
V TKL + EILQF++ VR DYRI+ LS +K F D D +L+ SA
Sbjct: 966 VMDTKLKIIEILQFILSVRLDYRISYMLSIYKKEFGEDNDNAETSASGSPDTLLPSAIVP 1025
Query: 3190 SINERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFT 3369
I+E A R + + LD G+ L +L+ + M DY PL S AL++ F+HF+
Sbjct: 1026 DIDEIAAQAETMFAGRKEKNPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFS 1085
Query: 3370 QYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDE 3549
Q E+L+ KQVQLLVSN DV+NY+QI DL L+ EKSELWV ++ + + E+ E
Sbjct: 1086 QRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWV--EKSSNYENGEIGE 1143
Query: 3550 KE-RTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRND 3726
+ + E + + ++ SP ++D
Sbjct: 1144 SQVKGGEEPIEESNILSP-----------------------------------VQDGTKK 1168
Query: 3727 AAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEFI 3906
+ D Y +++++L+RL+ +C + + K +Q+LLKNM + VVL+ +
Sbjct: 1169 PQI------DSNKSNKYRIVKEILIRLSKLCVQ--NKKCRNQHQRLLKNMGAHSVVLDLL 1220
Query: 3907 SVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEV 4086
+P++ K+D M +++ L+H FL++FC+ N +NQ L+K ++ G+L ET+
Sbjct: 1221 QIPYE-KNDEKMNEVMNLAHTFLQNFCRGNPQNQVLLHKHLNL--FLTPGLLEAETMRH- 1276
Query: 4087 GTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKV 4266
IF NN L + + E ++ H V IE + R+ +L LQ +V K ++ Q+ V
Sbjct: 1277 -----IFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDMV 1331
Query: 4267 ANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTR 4446
E+ ++V Y D ASF L MM E++ D L YHI LV LLA CT
Sbjct: 1332 MTELINGGEDVLIFYNDRASFPILLHMMCSERD----RGDESGPLAYHITLVELLAACTE 1387
Query: 4447 GKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYV 4626
GKN TE+KC S +P+D IVRVVT C+ EVK Y+ + HCY+DT+ EMK+ Y + ++
Sbjct: 1388 GKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNHI 1447
Query: 4627 DHILNNLLEDIRSLRVEKLTGAETAT--LEHYICHTVTEVLIKFFEAPYSALQQAKVDVH 4800
+ N L D+ + T + A LE + ++ ++ FF +P+S +
Sbjct: 1448 WKLFENFLVDMARV-CNTTTDRKHADIFLEKCVTESIMNIVSGFFNSPFS---DNSTSLQ 1503
Query: 4801 HHKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATL 4965
H+ F ++L + + V CI+ L + A+ I +P L
Sbjct: 1504 THQPVFIQLLQSAFRIYNCTWPNPAQKAS---VESCIRTLAEVAKNRGIAIPVDL 1555
>gi|13022060|gb|AAK11622.1| IP3 receptor isoform 2 [Rattus norvegicus]
gi|34851154|gb|AAQ82910.1| inositol trisphosphate receptor type 2
[Rattus norvegicus]
Length = 2701
Score = 930 bits (2403), Expect = 0.0
Identities = 613/1675 (36%), Positives = 903/1675 (53%), Gaps = 56/1675 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
L+IGDI+SLY E S N GF+STLGLVDDRC+V + G +PPKKFRDCLFKVCP+N
Sbjct: 9 LYIGDIVSLYAEGSVN----GFISTLGLVDDRCVVHPEAGDLTNPPKKFRDCLFKVCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + L+ KL+ AA+ E+++NESE +K LG +++Y +++Q
Sbjct: 65 RYSAQKQYWKAKQAKQGNHT--EAALLKKLQHAAELEQKQNESENRKLLGEIVKYSNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I P +K + GDN+ G+K+
Sbjct: 123 LLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L+P AG LH S+ LLD+ EVN +N T W++ +F+ F +++ +
Sbjct: 183 VLMP-----VNAGQ---PLHASNVELLDNPGCKEVNAVNCNTSWKITLFMKFSSYREDVL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ +FLR T R SA ATSS+ALWE++VV +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDDYEKKQH----IFLRTTLRQSATSATSSKALWEIEVVHHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG +WN +RFKHLAT YL+AE + P Y N DG
Sbjct: 291 PCRGGAGQWNSLFRFKHLATGNYLAAE-----LNPD---------YRDAQNEGKTVRDGE 336
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
+ + ++ ++ S D LF+LD +T +++ VPR SYVRL
Sbjct: 337 LPTSKKKRQAGEK------IMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLDF 1545
H ++ WV +T+ + ++ E+ +K+ + + DKE FA++ V EVRDLDF
Sbjct: 391 HLCTNTWVTSTS------IPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDF 444
Query: 1546 ANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSR 1725
ANDA K L +K ++ G + E T+LL D I FV + +++ D L + P+R
Sbjct: 445 ANDANKVLATTVKKLENGSITQNER-RFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNR 503
Query: 1726 DRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCL 1905
+RQKL+REQ +L QVF +LKAPF + G D R +K + +LCY +
Sbjct: 504 ERQKLMREQNILAQVFGILKAPFKEKAGE----GSMLRLEDLGDQRYAPYKYVLRLCYRV 559
Query: 1906 LKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFV 2085
L++SQ YRKNQE++A+ F +Q QIG+D++AEDT+TA+LHNN KLLEK++ +E FV
Sbjct: 560 LRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFV 619
Query: 2086 ELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII-------- 2241
L+R NR+ +FLDYL+DLCV A QELIC +LS + DI + TK++
Sbjct: 620 SLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPM 679
Query: 2242 ----------DGEIEVGW-----APNFRKLVDIAEGAKSNSD-DAEHLDYYRHQLDLLSQ 2373
D E+ + W P+ + + +A+ A+ + D E L YYR+QL+L ++
Sbjct: 680 ESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFAR 739
Query: 2374 MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS 2553
MC ++QYLAI+ IS QL +L+L+C+SD LP+DLR SF RLMLH+HV R
Sbjct: 740 MCLDRQYLAIN--------QISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDP 791
Query: 2554 PMSA--IRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGL 2727
S +R+ARLW IP + + Y+S+ +D SR + A + VE YL +
Sbjct: 792 QESVVPVRYARLWTEIPTKITIHEYDSI-----TDSSRNDMKRKFA-LTMEFVEEYLKEV 845
Query: 2728 RNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN--EGPATEQV 2901
NQ +KLT+E+V+LA+ L F FYSF++LL+LT+ LLAI++ + P +
Sbjct: 846 VNQPFPFGDK-EKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYF 904
Query: 2902 PSHRAMVNAIRNMSKSMMRGGNKENSKDLAK-----------TPSV-TAEEAGRTKEGRA 3045
+ N+ +++ G L++ PSV +++A ++
Sbjct: 905 ERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSVPDAQPSVHPSKQASPGEQEDV 964
Query: 3046 LNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSAS----------- 3192
+ TKL V EILQF++ VR DYRI+ LS +K F + DG+ SAS
Sbjct: 965 TVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFG-ENDGNGDPSASGTPETLLPSAL 1023
Query: 3193 ---INERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRH 3363
I+E A R + LD G+ L +L+ + M DY PL S AL++ F+H
Sbjct: 1024 VPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKH 1083
Query: 3364 FTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEV 3543
F+Q E+L+ KQVQLLVSN DV+NY+QI DL L+ EKSELWV
Sbjct: 1084 FSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWV------------- 1130
Query: 3544 DEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRN 3723
+ ++++GD E E NE LL+ +
Sbjct: 1131 ----------------EKSGSYENGDMGEGQAKGGEE-----ANEESNLLSPV------Q 1163
Query: 3724 DAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEF 3903
D A Q S+K Y +++++L+RL+ +C + + K +Q+LLKNM + VVL+
Sbjct: 1164 DGAKTPQIDSNKGN--NYRIVKEILIRLSKLCVQ--NKKCRNQHQRLLKNMGAHSVVLDL 1219
Query: 3904 ISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE 4083
+ +P++K D M +++ L+H FL++FC+ N +NQ L+K ++ G+L ET+
Sbjct: 1220 LQIPYEKT-DEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNL--FLTPGLLEAETMRH 1276
Query: 4084 VGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEK 4263
IF NN L + + E ++ H V IE + R+ +L LQ +V K ++ Q+
Sbjct: 1277 ------IFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDM 1330
Query: 4264 VANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCT 4443
V E+ ++V Y D ASF L MM E+ D L YHI LV LLA CT
Sbjct: 1331 VMTELINGGEDVLIFYNDRASFPILLNMMCSER----ARGDESGPLAYHITLVELLAACT 1386
Query: 4444 RGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY 4623
GKN TE+KC S +P+D IVRVVT C+ EVK Y+ + HCY+DT+ EMK+ Y + +
Sbjct: 1387 EGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNH 1446
Query: 4624 VDHILNNLLEDIRSLRVEKLTGAETAT-LEHYICHTVTEVLIKFFEAPYSALQQAKVDVH 4800
+ + N L D+ + T LE + +V ++ FF +P+S +
Sbjct: 1447 IWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFS---DNSTSLQ 1503
Query: 4801 HHKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATL 4965
H+ F ++L + + V CI+ L + A+ I +P L
Sbjct: 1504 THQPVFIQLLQSAFRIYNCTWPNPAQKAS---VESCIRALAEVAKNRGIAIPVDL 1555
>gi|13591975|ref|NP_112308.1| inositol 1,4,5-triphosphate receptor 2;
inositol 1,4,5-triphosphate receptor type 2; inositol
triphosphate receptor type 2; inositol 145-triphosphate
receptor 2; inositol 145-triphosphate receptor type 2
[Rattus norvegicus]
gi|266389|sp|P29995|IP3S_RAT Inositol 1,4,5-trisphosphate receptor
type 2 (Type 2 inositol 1,4,5-trisphosphate receptor)
(Type 2 InsP3 receptor) (IP3 receptor isoform 2)
(InsP3R2)
gi|111841|pir||S17796 inositol-trisphosphate receptor type 2 - rat
gi|56508|emb|CAA43852.1| inositol triphosphate receptor type 2
[Rattus norvegicus]
Length = 2701
Score = 929 bits (2402), Expect = 0.0
Identities = 615/1675 (36%), Positives = 903/1675 (53%), Gaps = 56/1675 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
L+IGDI+SLY E S N GF+STLGLVDDRC+V + G +PPKKFRDCLFKVCP+N
Sbjct: 9 LYIGDIVSLYAEGSVN----GFISTLGLVDDRCVVHPEAGDLTNPPKKFRDCLFKVCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + L+ KL+ AA+ E+++NESE +K LG +++Y ++Q
Sbjct: 65 RYSAQKQYWKAKQAKQGNHT--EAALLKKLQHAAELEQKQNESENRKLLGEIVKYSKVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I P +K + GDN+ G+K+
Sbjct: 123 LLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWKLRSEGDNIVVGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L+P AG LH S+ LLD+ EVN +N T W++ +F+ F +++ +
Sbjct: 183 VLMP-----VNAGQ---PLHASNVELLDNPGCKEVNAVNCNTSWKITLFMKFSSYREDVL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ +FLR T R SA ATSS+ALWE++VV +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDDYEKKQH----IFLRTTLRQSATSATSSKALWEIEVVHHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG +WN +RFKHLAT YL+AE + P Y N DG
Sbjct: 291 PCRGGAGQWNSLFRFKHLATGNYLAAE-----LNPD---------YRDAQNEGKTVRDGE 336
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
T++ + I V P ++ LF+LD +T +++ VPR SYVRL
Sbjct: 337 LP-TSKKKHQAGEKIMYTLVSVPHGNDIAS-----LFELDATTLQRADCLVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVNPDEVRDLDF 1545
H ++ WV +T+ + ++ E+ +K+ + + DKE FA++ V EVRDLDF
Sbjct: 391 HLCTNTWVTSTS------IPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDF 444
Query: 1546 ANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSR 1725
ANDA K L +K ++ G + E T+LL D I FV + +++ D L + P+R
Sbjct: 445 ANDANKVLATTVKKLENGSITQNER-RFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNR 503
Query: 1726 DRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCL 1905
+RQKL+REQ +L QVF +LKAPF + G D R +K + +LCY +
Sbjct: 504 ERQKLMREQNILAQVFGILKAPFKEKAGE----GSMLRLEDLGDQRYAPYKYVLRLCYRV 559
Query: 1906 LKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFV 2085
L++SQ YRKNQE++A+ F +Q QIG+D++AEDT+TA+LHNN KLLEK++ +E FV
Sbjct: 560 LRHSQQDYRKNQEYIAKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFV 619
Query: 2086 ELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKII-------- 2241
L+R NR+ +FLDYL+DLCV A QELIC +LS + DI + TK++
Sbjct: 620 SLLRRNREPRFLDYLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPM 679
Query: 2242 ----------DGEIEVGW-----APNFRKLVDIAEGAKSNSD-DAEHLDYYRHQLDLLSQ 2373
D E+ + W P+ + + +A+ A+ + D E L YYR+QL+L ++
Sbjct: 680 ESSILPDDIDDEEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFAR 739
Query: 2374 MCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGS 2553
MC ++QYLAI+ IS QL +L+L+C+SD LP+DLR SF RLMLH+HV R
Sbjct: 740 MCLDRQYLAIN--------QISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDP 791
Query: 2554 PMSA--IRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGL 2727
S +R+ARLW IP + + Y+S+ +D SR + A + VE YL +
Sbjct: 792 QESVVPVRYARLWTEIPTKITIHEYDSI-----TDSSRNDMKRKFA-LTMEFVEEYLKEV 845
Query: 2728 RNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN--EGPATEQV 2901
NQ +KLT+E+V+LA+ L F FYSF++LL+LT+ LLAI++ + P +
Sbjct: 846 VNQPFPFGDK-EKNKLTFEVVHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYF 904
Query: 2902 PSHRAMVNAIRNMSKSMMRGGNKENSKDLAK-----------TPSV-TAEEAGRTKEGRA 3045
+ N+ +++ G L++ PSV +++A ++
Sbjct: 905 ERLSKFQDGSNNVMRTIHGVGEMMTQMVLSRGSIFPVSWPDAQPSVHPSKQASPGEQEDV 964
Query: 3046 LNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSAS----------- 3192
+ TKL V EILQF++ VR DYRI+ LS +K F + DG+ SAS
Sbjct: 965 TVMDTKLKVIEILQFILSVRLDYRISYMLSIYKKEFG-ENDGNGDPSASGTPETLLPSAL 1023
Query: 3193 ---INERMASELYDAIYRSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRH 3363
I+E A R + LD G+ L +L+ + M DY PL S AL++ F+H
Sbjct: 1024 VPDIDEIAAQAETMFAGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKH 1083
Query: 3364 FTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEV 3543
F+Q E+L+ KQVQLLVSN DV+NY+QI DL L+ EKSELWV
Sbjct: 1084 FSQRAEVLQAFKQVQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWV------------- 1130
Query: 3544 DEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRN 3723
+ ++++GD E E NE LL+ +
Sbjct: 1131 ----------------EKSGSYENGDMGEGQAKGGEE-----ANEESNLLSPV------Q 1163
Query: 3724 DAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLLKNMRVYEVVLEF 3903
D A Q S+K Y +++++L+RL+ +C + + K +Q+LLKNM + VVL+
Sbjct: 1164 DGAKTPQIDSNKGN--NYRIVKEILIRLSKLCVQ--NKKCRNQHQRLLKNMGAHSVVLDL 1219
Query: 3904 ISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEE 4083
+ +P++K D M +++ L+H FL++FC+ N +NQ L+K ++ G+L ET+
Sbjct: 1220 LQIPYEKT-DEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNL--FLTPGLLEAETMRH 1276
Query: 4084 VGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEK 4263
IF NN L + + E ++ H V IE + R+ +L LQ +V K ++ Q+
Sbjct: 1277 ------IFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQDM 1330
Query: 4264 VANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCT 4443
V E+ ++V Y D ASF L MM E+ D L YHI LV LLA CT
Sbjct: 1331 VMTELINGGEDVLIFYNDRASFPILLNMMCSER----ARGDESGPLAYHITLVELLAACT 1386
Query: 4444 RGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEY 4623
GKN TE+KC S +P+D IVRVVT C+ EVK Y+ + HCY+DT+ EMK+ Y + +
Sbjct: 1387 EGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTSNH 1446
Query: 4624 VDHILNNLLEDIRSLRVEKLTGAETAT-LEHYICHTVTEVLIKFFEAPYSALQQAKVDVH 4800
+ + N L D+ + T LE + +V ++ FF +P+S +
Sbjct: 1447 IWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFS---DNSTSLQ 1503
Query: 4801 HHKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLPATL 4965
H+ F ++L + + V CI+ L + A+ I +P L
Sbjct: 1504 THQPVFIQLLQSAFRIYNCTWPNPAQKAS---VESCIRALAEVAKNRGIAIPVDL 1555
>gi|47219802|emb|CAG03429.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2747
Score = 929 bits (2401), Expect = 0.0
Identities = 616/1691 (36%), Positives = 910/1691 (53%), Gaps = 72/1691 (4%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI+SLY E S N GF+STLGLVDDRC+V+ G +PPKKFRDCLFKVCP+N
Sbjct: 9 LHIGDIVSLYAEGSVN----GFISTLGLVDDRCVVQPDAGDLANPPKKFRDCLFKVCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W + K+ + G+S DL KL+ AA+ E+++NESE +K LG V++Y +++Q
Sbjct: 65 RYSAQKQFW-KAKQGKQGNSNTQGDLFKKLQHAAELEQKQNESENKKLLGEVVKYSNVIQ 123
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNK++TV K PA E+NAM+V LD AGNEGSWF I+P +K + GDNV G+K+
Sbjct: 124 LLHIKSNKFLTVNKRLPALLEKNAMRVSLDPAGNEGSWFYIQPFWKLRSEGDNVVVGDKV 183
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L+P AG LH S+ LLD+ EVN +N T W++ +F+ F + +++ +
Sbjct: 184 VLMP-----VNAG---QPLHASNIELLDNPGCKEVNAVNCNTSWKITLFMKFSDYKEDVL 235
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D +Q VFLR T R SA ATSS+ALWEV+VV +
Sbjct: 236 KGGDVVRLFHAEQEKFLTCDEHRRQQH----VFLRTTLRQSATSATSSKALWEVEVVHYD 291
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAE--PSQVQVKPAMNG-RRASLIYSKTNNPMAMYS 1179
RGG +WN +RFKHLAT YL+AE P A G +++SK + A
Sbjct: 292 PCRGGAGQWNSLFRFKHLATGNYLAAEVNPEFKDNTTAPRGENETDVVFSKRKHQAA--- 348
Query: 1180 DGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYV 1359
E T ++P D LF+LD +T +++ VPR SYV
Sbjct: 349 --------EKITFTLVSVPH------------GNDIASLFELDATTLQRADCLVPRNSYV 388
Query: 1360 RLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDL 1539
RL H ++ WV +TN + + +K+ + DKE FA++ V EVRDL
Sbjct: 389 RLRHLCTNTWVTSTNVPID-----TEEERPVMLKIGTCPAKEDKEAFAIVSVPLSEVRDL 443
Query: 1540 DFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSP 1719
DFANDA K L + ++ ++ G + E T+LL D + FV ++ D L + +P
Sbjct: 444 DFANDASKVLESTVRKLQYGTITQNER-RFVTKLLEDLVFFVCVVPNNGQDVLSVVTSTP 502
Query: 1720 SRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCY 1899
+R+RQKL+REQ +L Q+F +LKAPF T D R FK M +LCY
Sbjct: 503 NRERQKLMREQNILAQIFGILKAPF-----TDQGDGPILRLEDLGDQRYAHFKYMLRLCY 557
Query: 1900 CLLKYSQVSYRKN--------------QEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNP 2037
+L++SQ YRKN QE++A+KF +Q QIG++++AEDT+TA+LHNN
Sbjct: 558 RVLRHSQQDYRKNQAGVVAIMWSFSALQEYIAKKFTIMQSQIGYEILAEDTITALLHNNR 617
Query: 2038 KLLEKYVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRD 2217
KLLEK++ +E FV L+R NR+ +FLDYL+DLCV A QELIC +L+ + D
Sbjct: 618 KLLEKHITAREIETFVNLLRRNREPRFLDYLSDLCVSNKTAIPVTQELICKFMLNPTNAD 677
Query: 2218 IFMDTKII-----------------DGEIEVGW-----APNFRKLVDIAEGAKS-NSDDA 2328
I + TK+I + E+ + W P+ + + +A+ AK + D
Sbjct: 678 ILIQTKLIANTETTLESSLLQEEVEEEEVWLYWIDSHKEPHGKSIRHLAQDAKGIHKMDV 737
Query: 2329 EHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRG 2508
+ + YYR+QL+L ++MC ++QYLAI+ +S QLP +L+L+CM D+ LPY+LR
Sbjct: 738 DIITYYRYQLNLFAKMCLDRQYLAIN--------QVSCQLPVDLILRCMFDDCLPYNLRA 789
Query: 2509 SFTRLMLHLHVVRGSPMSA--IRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGI 2682
SF RLMLH+HV R S +R+ARLW IP + + +E S +D SR +
Sbjct: 790 SFCRLMLHMHVDRDPQESVVPVRYARLWTEIPSKITIHEFEYES----TDTSREEMKRKF 845
Query: 2683 AHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNL 2862
A + VE YL + +Q + ++LT E+VNLA+ L F FYSF++LL+LT+ L
Sbjct: 846 A-PTMEFVEEYLRDVVSQPFPFGDK-DKNELTLEVVNLARNLVYFGFYSFSELLRLTRTL 903
Query: 2863 LAI-------------INEGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPS 3003
LAI +N+ P E + ++ + M M+ +S L TP
Sbjct: 904 LAILDIVQHPLSLINKLNKSP--EAGNNVLRTIHGVGEMMTQMVMSRGVPHS--LTDTPP 959
Query: 3004 VTAEEAGR--TKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCD---ED 3168
G + + + TKL + EILQF++ VR DYRIT LS +K F + E+
Sbjct: 960 SLRYGKGYFFSDNEDVMVMDTKLKIIEILQFILSVRLDYRITYLLSIYKKEFGDNSIVEN 1019
Query: 3169 GSLMHSASINERMASE--------LYDAIYRSSGH--ELHLDGRDGQLLLAILLQMTMSD 3318
S + ASE + ++ S + LD G+ L +L+ + M +
Sbjct: 1020 SMADCSTMLLFTPASEPDIDEITTKAETMFAGSSELSAVELDDEGGRTFLRVLIHLIMQE 1079
Query: 3319 YPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSEL 3498
YPPL S +L++ F+HF+Q E+L+ KQVQLLVS DVENY+QI DL L+ EKSEL
Sbjct: 1080 YPPLVSGSLQLLFKHFSQRAEVLQAFKQVQLLVSEQDVENYKQIKTDLDQLRLTVEKSEL 1139
Query: 3499 WVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNE 3678
WV ++ + V + + E +L SP
Sbjct: 1140 WVEKSGAYNGEDLAVRQGKEPNEEGVL-----SP-------------------------- 1168
Query: 3679 CLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQ 3858
++D N + + ++ Y +++++L+RL+ +CY K Q
Sbjct: 1169 ---------VQDGDNKPQIDSNKANN------YKIVKEILLRLSKLCY--PSKKSRVQQQ 1211
Query: 3859 QLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYE 4038
+LLKNM + VVL+ + +P++K D M +++TL+H FL++FC+ N +NQ L+K ++
Sbjct: 1212 RLLKNMGAHTVVLDLLQIPYEKS-DEKMNEIMTLAHTFLQNFCRGNPQNQVLLHKHLNL- 1269
Query: 4039 KDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQA 4218
G+L ET+ IF NN +L + + + ++ H V IE + ++ +L+ L+
Sbjct: 1270 -FLTPGLLEAETMRH------IFMNNYQLCNEISDRVVHHFVHCIETHGKHVQYLKFLET 1322
Query: 4219 LVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRK 4398
+V K ++ Q+KV E+ ++V Y D +SF L MM E+E +D
Sbjct: 1323 IVKADGKYVKKCQDKVMTELVNGGEDVLVFYNDRSSFPVLLQMMGSERE----RTDEDGA 1378
Query: 4399 LKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCY 4578
L YH LV LLA CT GKN TELKC S +P+D IVRVVT C+ EVKT Y+ + HCY
Sbjct: 1379 LAYHNTLVELLAACTEGKNVYTELKCNSLLPLDDIVRVVTDIHCVPEVKTAYVNFVNHCY 1438
Query: 4579 IDTDAEMKDAYKTEYVDHILNNLLEDIRSL--RVEKLTGAETATLEHYICHTVTEVLIKF 4752
+DT+ EMK+ Y + ++ + +N L D+ S + A++A LE Y+ TV ++ F
Sbjct: 1439 VDTEVEMKEIYTSNHIWKLFDNFLVDMSSACNTTTERNHADSA-LEKYVTETVMAIVKGF 1497
Query: 4753 FEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWA 4932
F +P+S ++ ++ F ++L + + N + CIK L A
Sbjct: 1498 FSSPFSV---NHANLQTNQSIFIKLLQSSFRIYNCTWLSAPQKAN---IESCIKTLADVA 1551
Query: 4933 EEHNITLPATL 4965
+ I +P L
Sbjct: 1552 KARAIAIPVDL 1562
>gi|18307586|dbj|BAB84088.1| inositol 1,4,5-trisphosphate receptor
[Asterina pectinifera]
Length = 2698
Score = 928 bits (2399), Expect = 0.0
Identities = 613/1678 (36%), Positives = 888/1678 (52%), Gaps = 59/1678 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LH GDI+SLY E S N GF+STLGLVDDRC+V+ G +PPKKFRDCLFK+CP+N
Sbjct: 9 LHFGDIVSLYAEGSVN----GFISTLGLVDDRCVVQPDFGDLNNPPKKFRDCLFKICPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY AQK W K S D L+ KL+ AA+ E+++NE+E +K +G+VI YG+++Q
Sbjct: 65 RYTAQKQFWKSAK--PNVSSATDAVLLKKLQHAAEMEKKQNETENKKLMGSVIVYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KS+KY+TV K PA E+NAM+V LD + EGSWF I P YK + GDNV G+K+
Sbjct: 123 LLHIKSHKYMTVNKRLPALLEKNAMRVTLDSSATEGSWFYIVPFYKLRSAGDNVVVGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH S++ L+D+ EVN +N T W+V +F+ EN + +
Sbjct: 183 VLNP-----VNAGQ---PLHPSNYELIDNPGCKEVNSVNCNTCWKVSLFMEHKENL-DGL 233
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K++ +FLR T R SA ATSS+ALWE +VVQ +
Sbjct: 234 KGGDVVRLFHAEQEKFLTCDEYKKKS----YIFLRTTGRVSATAATSSKALWETEVVQHD 289
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT Y++AE K + GP
Sbjct: 290 PCRGGAGHWNSLFRFKHLATGQYMAAEVDNDNTKDHTREKLR----------------GP 333
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
+G T Q +P + D +F+LDP+T + VPR SYVRL
Sbjct: 334 HG------GTVYQMVPIIH----------GNDIASIFELDPTTLQGGDSMVPRSSYVRLR 377
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ WVH+T+ + +++ +KV + R D+E FA++PV+P EVRDLDFA
Sbjct: 378 HLCTNTWVHSTSIPLDKG-----EDKPVMLKVGTAQIREDREAFAIIPVSPTEVRDLDFA 432
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA K L ++ + E TQLL D + FV+ ++ D L + +P RD
Sbjct: 433 NDANKVLSAIASKLEKSSITQNERF--VTQLLTDLVYFVSILPNNGGDALNVVVQNPDRD 490
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ++L Q+F +LKAPF T D R+ ++ + +LCY +L
Sbjct: 491 RQKLMREQDILKQIFKILKAPF-----TDNGDGAMLKMEELADPRHAPYRHICRLCYRIL 545
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
+ SQ +YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++ +E FV
Sbjct: 546 RLSQQAYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITATEIETFVN 605
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVG-- 2262
LVR N + +FL+YL+DLCV +A QELIC SVL ++ DI ++TK++ ++EV
Sbjct: 606 LVRKNGECRFLEYLSDLCVSNNQAIPVTQELICKSVLVERNSDILIETKLVRTQMEVEME 665
Query: 2263 -----------------------WAPNFR-KLVDIAEGAKSN-SDDAEHLDYYRHQLDLL 2367
W + K + G N +DA L YYR+QLDL
Sbjct: 666 VEADDGTTEPVYTIEEEEEVVLFWKNGTKSKSIRSCHGGTENVKEDANVLKYYRYQLDLF 725
Query: 2368 SQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVR 2547
SQMC ++QYLAI+ I QL +L+ +CMSD LPYDLR SFTRLMLH+HV R
Sbjct: 726 SQMCLDRQYLAIN--------QIGPQLDIDLIHRCMSDESLPYDLRASFTRLMLHMHVDR 777
Query: 2548 G--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLM 2721
++ +++A LW IP + + Y+ + ++ + + K VE YL
Sbjct: 778 DPKEQVTPVKYAELWSEIPTQITIDDYDGANNLTHAGKEDAQPKFSLTIKF---VEEYLC 834
Query: 2722 GLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN----EGPA 2889
+ + + +KLT+E+VNLAK L F FYSF++LL+LT+ LL+I++ G A
Sbjct: 835 NVVSGVLVVYDK-EQNKLTFEVVNLAKHLIYFGFYSFSELLRLTKTLLSILDCTALHGTA 893
Query: 2890 TEQVPSHRAM--------VNAIRNMSKSMMRGGNKEN--SKDLAKTPSVTAEEAGRTKEG 3039
++ + ++ + + +M+ G ++D A + + E
Sbjct: 894 PGKLDPKADIGKGGVFRSIHGVGAVMTNMVLGKRLPTPVTRDPAWPLGWGLDNHNKQDE- 952
Query: 3040 RALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMHSASINERMAS-- 3213
L ++TKL + +ILQF+++VR DYRI+ LS FK F +D + + S AS
Sbjct: 953 --LVMETKLKIIQILQFILNVRLDYRISCLLSIFKRDFDESKDSTDEITTSGKVWTASDF 1010
Query: 3214 ----ELYDAIYRSSGHELHLDGRD---GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQ 3372
E + I+ S LD D G+ L +L+ +TM DY PL S AL++ F+HF+Q
Sbjct: 1011 EHIEEQAEGIFGGSEENTPLDLDDDDGGRTFLRVLIHLTMHDYAPLVSGALQLLFKHFSQ 1070
Query: 3373 YQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEK 3552
QE+LE KQ+QLLVS+ DV+NY+QI +DL L+ L EKSELWV+ + + +D
Sbjct: 1071 RQEVLEAFKQLQLLVSSQDVDNYKQIKQDLDQLR-LVEKSELWVYKGQG---PDEPMDGA 1126
Query: 3553 ERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAA 3732
EH + P +S S
Sbjct: 1127 SGEQEHKKTEEGTSKPLKHESTSSYN---------------------------------- 1152
Query: 3733 VALQELSDKAPLIAYPLIRQMLVRLTGM-CYR-KGDPKPDTMNQQLLKNMRVYEVVLEFI 3906
Y +++++L+RL+ + C G K Q+LL+NM + VVLE +
Sbjct: 1153 --------------YRVVKEILLRLSKLVCVEGNGTRKNRKHEQRLLRNMGAFTVVLELL 1198
Query: 3907 SVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEV 4086
+P++K HD M +L+ L+HEFL++FC N NQ L+K I + + E
Sbjct: 1199 QIPYEKNHDTRMNELMRLAHEFLQNFCWANPSNQVLLHKHID--------LFLTPGLLEA 1250
Query: 4087 GTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKV 4266
T+ IF NN +L S V E+++ H V I + R+ +L+ LQA+V + I Q+ V
Sbjct: 1251 QTMCHIFMNNFQLCSEVTEQVVQHFVHCIATHGRHVQYLKFLQAIVKADGQYIRKTQDMV 1310
Query: 4267 ANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTR 4446
E+ A ++V Y D ASF+ MM+ E+E SS S+ + H L CT
Sbjct: 1311 MAELVNAGEDVLLFYNDKASFQMFINMMRTERERMDASSPSQYR---HQPWTLLGLACTE 1367
Query: 4447 GKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYV 4626
GKN TE+KC S +P+D IVRV T + CL EVK Y+ L HCY+DT+ EMK+ Y + +V
Sbjct: 1368 GKNVYTEIKCHSLLPLDDIVRVATHEDCLPEVKNAYINFLNHCYVDTEVEMKEIYTSNHV 1427
Query: 4627 DHILNNLLEDIRSL-RVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHH 4803
++ N L D+ + LE + TV ++ FF +P++ V
Sbjct: 1428 WNLFENFLVDMAMVCNATHDRKHHDHMLEKTVTETVMNIITMFFSSPFA---DQSTTVQT 1484
Query: 4804 HKKTFSEVLLELTYLEKGKLRGSK----SSRNWYRVAECIKRLTKWAEEHNITLPATL 4965
+ F +L +G R S+ + Y V CIK LT A+ I +P L
Sbjct: 1485 RQPVFVRLL-------QGAFRVSQCDWLTGHQKYHVENCIKTLTDIAKNRGIAIPVDL 1535
>gi|4504795|ref|NP_002215.1| inositol 1,4,5-triphosphate receptor,
type 3 [Homo sapiens]
gi|1082540|pir||A49873 inositol 1,4,5-triphosphate receptor, type 3 -
human
gi|393036|gb|AAC50064.1| human type 3 inositol 1,4,5-trisphosphate
receptor
Length = 2671
Score = 923 bits (2385), Expect = 0.0
Identities = 623/1717 (36%), Positives = 916/1717 (53%), Gaps = 75/1717 (4%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI+SLY E S N GF+STLGLVDDRC+VE G ++PPKKFRDCLFKVCP+N
Sbjct: 8 LHIGDIVSLYAEGSVN----GFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMN 63
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + D L+ KL+ AA E+++N++E +K G+V++YGS++Q
Sbjct: 64 RYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQ 123
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD GNEGSW I+P +K + GDNV G+K+
Sbjct: 124 LLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKV 183
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH S++ L D+ EVN +N T W++ +F+ F ++ + +
Sbjct: 184 ILNP-----VNAG---QPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVL 235
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D + VFLR T R SA ATSS ALWEV+VV +
Sbjct: 236 KGGDVVRLFHAEQEKFLTCDEYKGKLQ----VFLRTTLRQSATSATSSNALWEVEVVHHD 291
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN YRFKHLAT YL+AE + A + + A M + G
Sbjct: 292 PCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAA-----------GMGAQGR 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
G N + I V P + D LF+LDP+T K++ VPR SYVRL
Sbjct: 341 TGRRNAG-----EKIKYCLVAVPHGN-----DIASLFELDPTTLQKTDSFVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ W+ +TN + + + C + DKE FA++ V E+RDLDFA
Sbjct: 391 HLCTNTWIQSTNVP----IDIEEERPIRLMLGTC-PTKEDKEAFAIVSVPVSEIRDLDFA 445
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA L + ++ + G IS+ QLL D + FV++ ++ + L I P+R+
Sbjct: 446 NDASSMLASAVEKLNEG-FISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRE 504
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ +L QVF +LK PF + G D +N ++ MF+LCY +L
Sbjct: 505 RQKLMREQNILKQVFGILKVPFREKGG----EGPLVRLEELSDQKNAPYQHMFRLCYRVL 560
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
+YSQ YRKNQE +A++FG +Q QIG+D++AEDT+TA+LHNN KLLEK++ VE FV
Sbjct: 561 RYSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVS 620
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI---------- 2238
LVR NR+ +FLDYL+DLCV A QELIC VL K+ DI + T++
Sbjct: 621 LVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSH 680
Query: 2239 -------IDGEIEVGWAP-----NFRKLVDIAEGAKS-NSDDAEHLDYYRHQLDLLSQMC 2379
+ E+ + W + + + +A+ A++ N+ D L YYR+QL L ++MC
Sbjct: 681 EYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMC 740
Query: 2380 QEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP- 2556
++QYLAID ISQQL +L+ CM+D LP+DLR SF LMLH+HV R
Sbjct: 741 LDRQYLAID--------EISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQE 792
Query: 2557 -MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 2733
++ ++ ARLW IP + + Y+S ++ A D + + + VE YL + +
Sbjct: 793 LVTPVKFARLWTEIPTAITIKDYDS-NLNASRDDKKNKFA-----NTMEFVEDYLNNVVS 846
Query: 2734 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN--EGPATEQVPS 2907
+++ +KLT+E+V+LA L F FYSF++LL+LT+ LL II+ +GP
Sbjct: 847 EAVPFANE-EKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPP------ 899
Query: 2908 HRAMVNAI-----RNMSKSMMRGGNKENSKDLAKTPSV-----------TAEEAGRTK-- 3033
AM+ A +N+ +S+ G+ ++ L++ SV AE R+K
Sbjct: 900 --AMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFE 957
Query: 3034 EGRALNV-KTKLIVAEILQFVMDVRRDYRITMALSWFK----NVFPCDEDGS-------L 3177
E + V +TKL + EILQF+++VR DYRI+ LS FK VFP + G+
Sbjct: 958 ENEDIVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFD 1017
Query: 3178 MHSASINERMASELYDAIY--RSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKV 3351
+A++N E +A++ + L +D G++ L +L+ +TM DY PL S AL++
Sbjct: 1018 STTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQL 1077
Query: 3352 FFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSID 3531
F+HF+Q QE + KQVQLL+S DVENY+ I +L L+ + EKSELWV D+ S
Sbjct: 1078 LFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWV--DKKGSGK 1135
Query: 3532 TKEV------DEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLL 3693
+EV D+KER T+ + H P S ++ + + +L
Sbjct: 1136 GEEVEAGTAKDKKERPTDEEGFLH----PPGEKSSENYQIVKGILE-------------- 1177
Query: 3694 NRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQ-LLK 3870
RL MC G + QQ LLK
Sbjct: 1178 ------------------------------------RLNKMC---GVGEQMRKKQQRLLK 1198
Query: 3871 NMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAK 4050
NM ++V+L+ + +P+D K D MM+++ +H+FL+ FC N NQ+ L+K +
Sbjct: 1199 NMDAHKVMLDLLQIPYD-KGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHL--HLFLT 1255
Query: 4051 EGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCV 4230
G+L ET++ IF NN +L S + E ++ H V L+ + R+ +L+ L ++
Sbjct: 1256 PGLLEAETMQH------IFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKA 1309
Query: 4231 YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYH 4410
K ++ Q+ + E+ A D+V Y D AS L MMK ++ + L YH
Sbjct: 1310 EGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARD----GVEDHSPLMYH 1365
Query: 4411 IELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTD 4590
I LV LLA C GKN TE+KC S +P++ +V VVT + C+ EVK Y+ + HCY+DT+
Sbjct: 1366 ISLVDLLAACAEGKNVYTEIKCTSLVPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTE 1425
Query: 4591 AEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYS 4770
EMK+ Y + ++ + N D+ + ++ TLE Y+ V + + FF +P+S
Sbjct: 1426 VEMKEIYTSNHIWTLFENFTLDMARVCSKREKRVADPTLEKYVLSVVLDTINAFFSSPFS 1485
Query: 4771 ALQQAKVDVHHHKKTFSEV------LLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWA 4932
+ + H+ ++ LLE +L++ + +GS V CI+ L A
Sbjct: 1486 ---ENSTSLQTHQPVVVQLLQSTTRLLECPWLQQ-QHKGS--------VEACIRTLAMVA 1533
Query: 4933 EEHNITLPATL---AGPQMSGQTSVRQKWQQAASSAK 5034
+ I LP L +S S Q+ ASS K
Sbjct: 1534 KGRAILLPMDLDAHISSMLSSGASCAAAAQRNASSYK 1570
>gi|17366458|sp|Q14573|IP3T_HUMAN Inositol 1,4,5-trisphosphate
receptor type 3 (Type 3 inositol 1,4,5-trisphosphate
receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform
3) (InsP3R3)
gi|483831|dbj|BAA05385.1| type 3 inositol 1,4,5-trisphosphate
receptor [Homo sapiens]
Length = 2671
Score = 921 bits (2381), Expect = 0.0
Identities = 625/1715 (36%), Positives = 919/1715 (53%), Gaps = 73/1715 (4%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI+SLY E S N GF+STLGLVDDRC+VE G ++PPKKFRDCLFKVCP+N
Sbjct: 8 LHIGDIVSLYAEGSVN----GFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMN 63
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + D L+ KL+ AA E+++N++E +K G+V++YGS++Q
Sbjct: 64 RYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQ 123
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD GNEGSW I+P +K + GDNV G+K+
Sbjct: 124 LLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKV 183
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH S++ L D+ EVN +N T W++ +F+ F ++ + +
Sbjct: 184 ILNP-----VNAG---QPLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVL 235
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D + VFLR T R SA ATSS ALWEV+VV +
Sbjct: 236 KGGDVVRLFHAEQEKFLTCDEYKGKLQ----VFLRTTLRQSATSATSSNALWEVEVVHHD 291
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN YRFKHLAT YL+AE + A + + A M + G
Sbjct: 292 PCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDASDPKAA-----------GMGAQGR 340
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
G N + I V P + D LF+LDP+T K++ VPR SYVRL
Sbjct: 341 TGRRNAG-----EKIKYCLVAVPHGN-----DIASLFELDPTTLQKTDSFVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ W+ +TN + + + C + DKE FA++ V E+RDLDFA
Sbjct: 391 HLCTNTWIQSTNVP----IDIEEERPIRLMLGTC-PTKEDKEAFAIVSVPVSEIRDLDFA 445
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA L + ++ + G IS+ QLL D + FV++ ++ + L I P+R+
Sbjct: 446 NDASSMLASAVEKLNEG-FISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRE 504
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ +L QVF +LKAPF + G D +N ++ MF+LCY +L
Sbjct: 505 RQKLMREQNILKQVFGILKAPFREKGG----EGPLVRLEELSDQKNAPYQHMFRLCYRVL 560
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
++SQ YRKNQE +A++FG +Q QIG+D++AEDT+TA+LHNN KLLEK++ VE FV
Sbjct: 561 RHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVS 620
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI---------- 2238
LVR NR+ +FLDYL+DLCV A QELIC VL K+ DI + T++
Sbjct: 621 LVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIRTELRPVKEMAQSH 680
Query: 2239 -------IDGEIEVGWAP-----NFRKLVDIAEGAKS-NSDDAEHLDYYRHQLDLLSQMC 2379
+ E+ + W + + + +A+ A++ N+ D L YYR+QL L ++MC
Sbjct: 681 EYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMC 740
Query: 2380 QEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP- 2556
++QYLAID ISQQL +L+ CM+D LP+DLR SF LMLH+HV R
Sbjct: 741 LDRQYLAID--------EISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQE 792
Query: 2557 -MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 2733
++ ++ ARLW IP + + Y+S ++ A D + + + VE YL + +
Sbjct: 793 LVTPVKFARLWTEIPTAITIKDYDS-NLNASRDDKKNKFA-----NTMEFVEDYLNNVVS 846
Query: 2734 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN--EGPATEQVPS 2907
+++ +KLT+E+V+LA L F FYSF++LL+LT+ LL II+ +GP
Sbjct: 847 EAVPFANE-EKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQGPP------ 899
Query: 2908 HRAMVNAI-----RNMSKSMMRGGNKENSKDLAKTPSV-----------TAEEAGRTK-- 3033
AM+ A +N+ +S+ G+ ++ L++ SV AE R+K
Sbjct: 900 --AMLQAYEDPGGKNVRRSIQGVGHMMSTMVLSRKQSVFSAPSLSAGASAAEPLDRSKFE 957
Query: 3034 EGRALNV-KTKLIVAEILQFVMDVRRDYRITMALSWFK----NVFPCDEDGS-------L 3177
E + V +TKL + EILQF+++VR DYRI+ LS FK VFP + G+
Sbjct: 958 ENEDIVVMETKLKILEILQFILNVRLDYRISHLLSVFKKEFVEVFPMQDSGADGTAPAFD 1017
Query: 3178 MHSASINERMASELYDAIY--RSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKV 3351
+A++N E +A++ + L +D G++ L +L+ +TM DY PL S AL++
Sbjct: 1018 STTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLIHLTMHDYAPLVSGALQL 1077
Query: 3352 FFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSID 3531
F+HF+Q QE + KQVQLL+S DVENY+ I +L L+ + EKSELWV D+ S
Sbjct: 1078 LFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWV--DKKGSGK 1135
Query: 3532 TKEV------DEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLL 3693
+EV D+KER T+ + H P S ++ + + +L
Sbjct: 1136 GEEVEAGAAKDKKERPTDEEGFLH----PPGEKSSENYQIVKGILE-------------- 1177
Query: 3694 NRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQ-LLK 3870
RL MC G + QQ LLK
Sbjct: 1178 ------------------------------------RLNKMC---GVGEQMRKKQQRLLK 1198
Query: 3871 NMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAK 4050
NM ++V+L+ + +P+D K D MM+++ +H+FL+ FC N NQ+ L+K +
Sbjct: 1199 NMDAHKVMLDLLQIPYD-KGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHL--HLFLT 1255
Query: 4051 EGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCV 4230
G+L ET++ IF NN +L S + E ++ H V L+ + R+ +L+ L ++
Sbjct: 1256 PGLLEAETMQH------IFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKA 1309
Query: 4231 YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYH 4410
K ++ Q+ + E+ A D+V Y D AS L MMK ++ + L YH
Sbjct: 1310 EGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARD----GVEDHSPLMYH 1365
Query: 4411 IELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTD 4590
I LV LLA C GKN TE+KC S +P++ +V VVT + C+ EVK Y+ + HCY+DT+
Sbjct: 1366 ISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTE 1425
Query: 4591 AEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYS 4770
EMK+ Y + ++ + N D+ + ++ TLE Y+ V + + FF +P+S
Sbjct: 1426 VEMKEIYTSNHIWTLFENFTLDMARVCSKREKRVADPTLEKYVLSVVLDTINAFFSSPFS 1485
Query: 4771 ----ALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEE 4938
+LQ + V ++ + LLE +L++ + +GS V CI+ L A+
Sbjct: 1486 ENSTSLQTHQTIVVQLLQSTTR-LLECPWLQQ-QHKGS--------VEACIRTLAMVAKG 1535
Query: 4939 HNITLPATL---AGPQMSGQTSVRQKWQQAASSAK 5034
I LP L +S S Q+ ASS K
Sbjct: 1536 RAILLPMDLDAHISSMLSSGASCAAAAQRNASSYK 1570
>gi|6981110|ref|NP_037270.1| inositol 1, 4, 5-triphosphate receptor 3
[Rattus norvegicus]
gi|17365979|sp|Q63269|IP3T_RAT Inositol 1,4,5-trisphosphate receptor
type 3 (Type 3 inositol 1,4,5-trisphosphate receptor)
(Type 3 InsP3 receptor) (IP3 receptor isoform 3)
(InsP3R3) (IP3R-3)
gi|423895|pir||A46719 inositol 1,4,5-trisphosphate receptor subtype 3
- rat
gi|310171|gb|AAA41446.1| inositol triphosphate receptor subtype 3
Length = 2670
Score = 918 bits (2372), Expect = 0.0
Identities = 612/1690 (36%), Positives = 912/1690 (53%), Gaps = 71/1690 (4%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI+SLY E S N GF+STLGLVDDRC+VE G ++PPKKFRDCLFKVCP+N
Sbjct: 8 LHIGDIVSLYAEGSVN----GFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMN 63
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + D L+ KL+ AA E+++N++E +K G+V++YGS++Q
Sbjct: 64 RYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQ 123
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD GNEGSW I+P +K + GDNV G+K+
Sbjct: 124 LLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKV 183
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH S++ L D+ EVN +N T W++ +F+ F ++ + +
Sbjct: 184 ILNP-----VNAG---QPLHASNYELSDNVGCKEVNSVNCNTSWKINLFMQFRDHLEEVL 235
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D + VFLR T R SA ATSS ALWEV+VV +
Sbjct: 236 KGGDVVRLFHAEQEKFLTCDEYRGKLQ----VFLRTTLRQSATSATSSNALWEVEVVHHD 291
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN YRFKHLAT YL+AE + P+ G ++P A GP
Sbjct: 292 PCRGGAGHWNGLYRFKHLATGNYLAAEEN-----PSYKG--------DVSDPKAA---GP 335
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
+ + I V P + D LF+LDP+T K++ VPR SYVRL
Sbjct: 336 GAQSRTGRRNAGEKIKYRLVAVPHGN-----DIASLFELDPTTLQKTDSFVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ W+ +TNA + + + C + DKE FA++ V E+RDLDFA
Sbjct: 391 HLCTNTWIQSTNAP----IDVEEERPIRLMLGTC-PTKEDKEAFAIVSVPVSEIRDLDFA 445
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA L + ++ + G IS+ QLL D + FV++ ++ + L I P+R+
Sbjct: 446 NDASSMLASAVEKLNEG-FISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRE 504
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+R++ +L Q+F +LKAPF + G D +N ++ MF+LCY +L
Sbjct: 505 RQKLMRDENILKQIFGILKAPFRDKGG----EGPLVRLEELSDQKNAPYQYMFRLCYRVL 560
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
++SQ YRKNQE +A++FG +Q QIG+D++AEDT+TA+LHNN KLLEK++ VE FV
Sbjct: 561 RHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVS 620
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI---------- 2238
LVR NR+ +FLDYL+DLCV A QELIC VL K+ DI + T++
Sbjct: 621 LVRKNREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSH 680
Query: 2239 -------IDGEIEVGWAP-----NFRKLVDIAEGAKS-NSDDAEHLDYYRHQLDLLSQMC 2379
+ E+ + W + + + +A+ A++ N+ D L YYR+QL L ++MC
Sbjct: 681 EYLSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMC 740
Query: 2380 QEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP- 2556
++QYLAID IS+QL EL+ CM+D LP+DLR SF LMLH+HV R
Sbjct: 741 LDRQYLAID--------EISKQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQE 792
Query: 2557 -MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 2733
++ ++ ARLW IP + + Y+S ++ A D + +K +T+E L N
Sbjct: 793 LVTPVKFARLWTEIPTAITIKDYDS-NLNASRDDKK--------NKFASTMEFVEDYLNN 843
Query: 2734 QSMEERQSVNSSK--LTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIINEGPATEQVPS 2907
E N K LT+E+V+LA L F FYSF++LL+LT+ LL II + + +
Sbjct: 844 VVGEAVPFANDEKNILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGII------DCIQA 897
Query: 2908 HRAMVNAI-----RNMSKSMMRGGNKENSKDLAKTPSV-----------TAEEAGRTK-- 3033
A++ A +N+ +S+ G+ ++ L++ SV E+ R+K
Sbjct: 898 PAAVLQAYEEPGGKNVRRSIQGVGHMMSTMVLSRKQSVFGASSLPTGVGVPEQLDRSKFE 957
Query: 3034 -EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFK----NVFPCDEDGS-------L 3177
+ ++TKL + EILQF+++VR DYRI+ LS FK VFP + G+
Sbjct: 958 DNEHTVVMETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFD 1017
Query: 3178 MHSASINERMASELYDAIY--RSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKV 3351
+A++N E +A++ + L +D G++ L +LL +TM DYPPL S AL++
Sbjct: 1018 SSTANMNLDRIGEQAEAMFGVGKTSSMLEVDDEGGRMFLRVLLHLTMHDYPPLVSGALQL 1077
Query: 3352 FFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSID 3531
F+HF+Q QE + KQVQLL+S DVENY+ I +L L+ + EKSELWV D+ S+
Sbjct: 1078 LFKHFSQRQEAMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWV--DKKGSVK 1135
Query: 3532 TKE------VDEKERTTEHD--LLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQ 3687
+E D+KER ++ + L H KS +E+Y ++
Sbjct: 1136 GEEGEAGASKDKKERPSDEEGFLQPHGEKS-----------------SENYQIVKG---- 1174
Query: 3688 LLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQLL 3867
+L RL MC + Q+LL
Sbjct: 1175 -----------------------------------ILERLNKMC--GVGEQMRKKQQRLL 1197
Query: 3868 KNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDA 4047
KNM ++V+L+ + +P+D K+D+ MM+++ +H+FL+ FC N NQ+ L+K + +
Sbjct: 1198 KNMDAHKVMLDLLQIPYD-KNDNKMMEILRYTHQFLQKFCAGNPGNQALLHKHL--QLFL 1254
Query: 4048 KEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVC 4227
G+L ET++ IF NN +L S + E ++ H V + R+ +L+ L ++
Sbjct: 1255 TPGLLEAETMQH------IFLNNYQLCSEISEPVLQHFVHCWPTHGRHVQYLDFLHTVIK 1308
Query: 4228 VYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKY 4407
K ++ Q+ + E+ A D+V Y D AS L MMK ++ + L Y
Sbjct: 1309 AEGKYVKKCQDMIMTELTNAGDDVVVFYNDKASLAHLLDMMKAARD----GVEDHSPLMY 1364
Query: 4408 HIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDT 4587
HI LV LLA C GKN TE+KC S +P++ +V VVT + C+ EVK Y+ + HCY+DT
Sbjct: 1365 HISLVDLLAACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDT 1424
Query: 4588 DAEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPY 4767
+ EMK+ Y + ++ + N D+ + ++ TLE Y+ V + + FF +P+
Sbjct: 1425 EVEMKEIYTSNHIWTLFENFTLDMALVCNKREKRLSDPTLEKYVLTVVLDTISAFFSSPF 1484
Query: 4768 S----ALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAE 4935
S +LQ + V ++ + LLE +L++ + +GS V C++ L A+
Sbjct: 1485 SENSTSLQTHQTIVVQLLQSTTR-LLECPWLQQ-QHKGS--------VEACVRTLAMVAK 1534
Query: 4936 EHNITLPATL 4965
I LP L
Sbjct: 1535 SRAILLPMDL 1544
>gi|27805963|ref|NP_776795.1| inositol 1,4,5-triphosphate receptor,
type 3 [Bos taurus]
gi|17432548|gb|AAL39078.1| inositol 1,4,5-trisphosphate receptor type
3 [Bos taurus]
Length = 2664
Score = 910 bits (2351), Expect = 0.0
Identities = 608/1683 (36%), Positives = 903/1683 (53%), Gaps = 64/1683 (3%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI+SLY E S N GF+STLGLVDDRC+VE G ++PPKKFRDCLFKVCP+N
Sbjct: 8 LHIGDIVSLYAEGSVN----GFISTLGLVDDRCVVEPAAGDLDNPPKKFRDCLFKVCPMN 63
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W ++ Q + + D L+ KL+ AA E+++N++E +K G+V++YGS++Q
Sbjct: 64 RYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQKQNDTENKKVHGDVVKYGSVIQ 123
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD GNEGSW I+P +K + GDNV G+K+
Sbjct: 124 LLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGSWLFIQPFWKLRSNGDNVVVGDKV 183
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH S++ L D+ EVN +N T W++ +F+ F ++ + +
Sbjct: 184 ILNP-----VNAGQ---PLHASNYELSDNAGCKEVNSVNCNTSWKINLFMQFRDHLEEVL 235
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D + VFLR T R SA ATSS ALWEV+VV +
Sbjct: 236 KGGDVVRLFHAEQEKFLTCDEYRGKLQ----VFLRTTLRQSATSATSSNALWEVEVVHHD 291
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN YRFKHLAT YL+AE + P+ G ++P A G
Sbjct: 292 PCRGGAGHWNGLYRFKHLATGNYLAAEEN-----PSYKG--------DASDPKAA-GTGA 337
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
G T + I V P ++ LF+LDP+T K++ VPR SYVRL
Sbjct: 338 QGRTGRRN--AGEKIKYRLVAVPHGNDIAS-----LFELDPTTLQKTDSFVPRNSYVRLR 390
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRDLDFA 1548
H ++ W+ +TN + + + C + DKE FA++ V E+RDLDFA
Sbjct: 391 HLCTNTWIQSTNVP----IDVEEERPIRLMLGTCP-TKEDKEAFAIVSVPVSEIRDLDFA 445
Query: 1549 NDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSRD 1728
NDA L + ++ + G IS+ QLL D + FV++ ++ + L I P+R+
Sbjct: 446 NDASSMLASAVEKLHEG-FISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRE 504
Query: 1729 RQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCLL 1908
RQKL+REQ +L Q+F +LKAPF + G D +N ++ MF+LCY +L
Sbjct: 505 RQKLMREQNILKQIFGILKAPFRDKGGE----GPLVRLEELSDQKNAPYQHMFRLCYRVL 560
Query: 1909 KYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFVE 2088
++SQ YRKNQE +A++FG +Q QIG+D++AEDT+TA+LHNN KLLEK++ VE FV
Sbjct: 561 RHSQEDYRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVS 620
Query: 2089 LVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI---------- 2238
LVR NR+ +FLDYL+DLCV A QELIC VL K+ DI + T++
Sbjct: 621 LVRKNREPRFLDYLSDLCVSNHIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSH 680
Query: 2239 -------IDGEIEVGWAP-----NFRKLVDIAEGAKS-NSDDAEHLDYYRHQLDLLSQMC 2379
+ E+ + W + + + +A+ A++ N+ D L YYR+QL L ++MC
Sbjct: 681 EYLSIEYSEEEVWLTWTDKNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMC 740
Query: 2380 QEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRGSP- 2556
++QYLAID ISQQL +L+ CM+D LP+DLR SF LMLH+HV R
Sbjct: 741 LDRQYLAID--------EISQQLGVDLIFLCMADEMLPFDLRASFCHLMLHVHVDRDPQE 792
Query: 2557 -MSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRN 2733
++ ++ ARLW IP + + Y+S ++ A D + + + VE YL + +
Sbjct: 793 LVTPVKFARLWTEIPTAITIKDYDS-NLNASRDDKKNKFA-----STMEFVEDYLNNVVS 846
Query: 2734 QSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN-----EGPATEQ 2898
+++ +KLT+E+V+LA L F FYSF++LL+LT+ LL II+ E P +
Sbjct: 847 EAVPFANE-EKNKLTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCVQAYEDPGGKN 905
Query: 2899 VPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAE-------EAGRTKEGRALNV- 3054
V R + +M +M+ N++ S + PS+ A + + +E + V
Sbjct: 906 V---RRSTQGVGHMMSTMVL--NRKQS--VFGGPSLPAGAGAPEPLDGSKFEENEDIVVM 958
Query: 3055 KTKLIVAEILQFVMDVRRDYRITMALSWFK----NVFPCDEDGS-------LMHSASINE 3201
+TKL + EILQF+++VR DYRI+ LS FK VFP + G+ +A++N
Sbjct: 959 ETKLKILEILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSTTANMNL 1018
Query: 3202 RMASELYDAIY--RSSGHELHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQY 3375
E +A++ + L +D G++LL +L+ +TM DY PL S AL++ F+HF+Q
Sbjct: 1019 DRIGEQAEAMFGVGKTSSMLEVDDEGGRMLLRVLIHLTMHDYAPLVSGALQLLFKHFSQR 1078
Query: 3376 QELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWV------HGDRHHSIDTK 3537
QE++ KQVQLL+S DVENY+ I +L L+ + EKSELWV G+ + K
Sbjct: 1079 QEVMHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGASKGEEGEAGPAK 1138
Query: 3538 EVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDD 3717
D+KER T+ + H P S ++ + + +L
Sbjct: 1139 --DKKERPTDEEGFLH----PPGEKSSENYQIVKGILE---------------------- 1170
Query: 3718 RNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKGDPKPDTMNQQ-LLKNMRVYEVV 3894
RL MC G + QQ LLKNM ++V+
Sbjct: 1171 ----------------------------RLNKMC---GVGEQMRKKQQRLLKNMDAHKVM 1199
Query: 3895 LEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVET 4074
L+ + +P+D K D MM+++ +H+FL+ FC N NQ+ L+K + G+L ET
Sbjct: 1200 LDLLQIPYD-KGDAKMMEILRYTHQFLQKFCAGNPGNQALLHKHL--HLFLTPGLLEAET 1256
Query: 4075 IEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESG 4254
++ IF NN +L S + E ++ H V L+ + + +L+ L ++ K ++
Sbjct: 1257 MQH------IFLNNYQLCSEIGEPVLQHFVHLLATHGHHVQYLDFLHTVIKAEGKYVKKC 1310
Query: 4255 QEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLA 4434
Q+ + E A D+V Y D AS L MMK ++ + L YHI LV LLA
Sbjct: 1311 QDMIMTEPANAGDDVVVFYNDKASLAHLLDMMKAARD----GVEDHSPLMYHISLVDLLA 1366
Query: 4435 MCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYK 4614
C GKN TE+KC S +P++ +V VVT + C+ EVK Y+ + HCY+DT+ EMK+ Y
Sbjct: 1367 ACAEGKNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYT 1426
Query: 4615 TEYVDHILNNLLEDIRSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVD 4794
+ ++ + N D+ + ++ LE Y+ V + + FF +P+S +
Sbjct: 1427 SNHIWTLFENFTLDMARVCSKREKRLADPALEKYVLTVVLDTISAFFSSPFS---ENSTS 1483
Query: 4795 VHHHKKTFSEV------LLELTYLEKGKLRGSKSSRNWYRVAECIKRLTKWAEEHNITLP 4956
+ H+ ++ LLE +L++ + +GS V CI+ L A+ I+LP
Sbjct: 1484 LQTHQTIVVQLLQSTMRLLECPWLQQ-QHKGS--------VEACIRTLAMVAKGRAISLP 1534
Query: 4957 ATL 4965
L
Sbjct: 1535 MDL 1537
>gi|31217824|ref|XP_316515.1| ENSANGP00000004303 [Anopheles gambiae]
gi|30176080|gb|EAA11872.2| ENSANGP00000004303 [Anopheles gambiae str.
PEST]
Length = 2636
Score = 868 bits (2243), Expect = 0.0
Identities = 594/1620 (36%), Positives = 867/1620 (52%), Gaps = 64/1620 (3%)
Frame = +1
Query: 385 AADKEREENESEFQKTLGNVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRA 564
AA+ E+++NESE +K LG V+QYGS+VQLLH+KSNKY+TV PA E+NAM+VYLD
Sbjct: 3 AAEIEKKQNESENKKLLGTVVQYGSVVQLLHLKSNKYVTVNIRLPALLEKNAMRVYLDAN 62
Query: 565 GNEGSWFIIEPAYKHYAIGDNVSAGNKISLIPNSVSTTQAGHVKSQLHLS-SFNLLDHQS 741
GNEGSWF I P YK + GDNV +K+ L P + + + LH++ ++ L D+
Sbjct: 63 GNEGSWFYIMPFYKLRSAGDNVVVSDKVILKPVNAN-------RQNLHVAVTYELPDNPG 115
Query: 742 AAEVNCLNEPTEWQVFMFLLFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDV 921
+ EVN LN T W++ +F+ ENQ++ +K GDVVRLFHA+Q+ FLT+D KQ
Sbjct: 116 SKEVNVLNSSTSWKITLFMEQRENQEDVLKGGDVVRLFHAEQEKFLTMDEYKKQQH---- 171
Query: 922 VFLRMTNRPSAADATSSRALWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQV 1101
VFLR T R SA ATSS+ALWEV+VVQ ++ RGG WN +RFKHLAT YL+AE
Sbjct: 172 VFLRTTGRSSATAATSSKALWEVEVVQHDSCRGGAGHWNSLFRFKHLATGYYLAAE---- 227
Query: 1102 QVKPAMNGRRASLIYSKTNNPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEE 1281
D T +S+ ++ + L P
Sbjct: 228 -------------------------IDEDISRTEKSSSSSHPQGGDSFRLVPVPHS---S 259
Query: 1282 DANLLFQLDPSTFMKSNKEVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKGWVK 1461
D +F+LD +T + VP+ SYVRL H S WVHAT+ + ++ K
Sbjct: 260 DIASVFELDSTTITRPEGLVPQSSYVRLRHLCSSTWVHATSVPIDID-----DDKPVMSK 314
Query: 1462 VICEKNRVDKETFALLPVNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQL 1641
V C + DKE F L+PV+P EVRDLDFANDACK L ++ G + S E S L
Sbjct: 315 VGCSAIKEDKEAFQLIPVSPVEVRDLDFANDACKLLLAMSTKLENGTISSNER-RSLIAL 373
Query: 1642 LIDCILFVTNSSD--HLADPLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTT 1815
L D + F+ + + +D L ++ +P+RDRQKLLREQ +L Q+F +L+ PF Q T
Sbjct: 374 LQDIVFFIAGQENDQNKSDALDLTINNPNRDRQKLLREQYILKQLFKILQGPF---QETK 430
Query: 1816 XXXXXXXXXXXXXDSRNEIFKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDL 1995
D +N FK +F+LCY +LK SQ YRKNQE++A+ FG +Q+QIG+D+
Sbjct: 431 NNDGPFLKIDELGDPKNAPFKNIFRLCYRILKLSQQDYRKNQEYIAKHFGLMQKQIGYDI 490
Query: 1996 MAEDTMTAVLHNNPKLLEKYVKTPHVERFVELVRNNR---QGKFLDYLADLCVCRGEANK 2166
+AEDT+TA+LHNN KLLEK++ +E FV LVR N Q +FLDYL+DLCV +A
Sbjct: 491 LAEDTITALLHNNRKLLEKHITAAEIETFVGLVRKNMQSWQSRFLDYLSDLCVSNKKAIA 550
Query: 2167 KIQELICTSVLSSKHRDIFMDTKIID---------GEIEVG------------WA--PNF 2277
QELIC SVLSSK+ DI ++T + + E+E G W
Sbjct: 551 VTQELICKSVLSSKNADILIETFLREVDDDPLGYLSELERGNHEKKRYEVVLMWTNRTQS 610
Query: 2278 RKLVDIAEGAK-SNSDDAEHLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPA 2454
+ + +A+G K + D LDYYRHQL+L S MC +QYLA++ N+S L
Sbjct: 611 KSMSRLAQGLKIGRAVDTAILDYYRHQLNLFSNMCLNRQYLALN--------NLSPHLDI 662
Query: 2455 ELVLQCMSDNRLPYDLRGSFTRLMLHLHVVRG--SPMSAIRHARLWWSIPENVNVSTYES 2628
+L+L+CMSD +PYDLR SF RLMLHLHV R P++ +++ARLW IP ++++ Y+
Sbjct: 663 DLILRCMSDKTVPYDLRASFCRLMLHLHVDRDPQEPVTPVKYARLWSEIPTVMSINDYD- 721
Query: 2629 VSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKAL 2808
+E D ++ + +K +A VE YL M + +KLT+E+V LA+ L
Sbjct: 722 --IEKQLDSNKEAV-RARFNKTIAFVEDYLCNHVVSKMWFADQ-DQNKLTFEVVKLARDL 777
Query: 2809 AQFNFYSFNDLLQLTQNLLAII-----NEGPATEQVPSH--RAMVNAIRNMSKSMMRGGN 2967
F FYSF+DLL+LT+ LL I+ +E T H ++ I +M M
Sbjct: 778 IYFGFYSFSDLLRLTKTLLNILDCVSSSEADGTGLPTGHIDCGVLRRIGDMGAVMTSLTL 837
Query: 2968 KENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKN 3147
S + + + + L + TKL + EILQF++DVR DYRI+ LS FK
Sbjct: 838 GPISTAIVSPTIQHRKSVSQLMKEYPLVMDTKLKIIEILQFILDVRLDYRISCLLSIFKR 897
Query: 3148 VFPCDE-------DGSLMHSA-SINERMAS-ELYDAIYRSSG---------HELHLDGRD 3273
F +E D SL +A +IN R + +L Y++ G + L LDG+
Sbjct: 898 EFDENEQTASTATDTSLPPTAENINLRQKNIDLESIGYQAEGIFGCTEDTYNPLDLDGQG 957
Query: 3274 GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQID 3453
G+ L +LL + M +YP L S AL + FRHF+Q E+L +QVQLLVS++DVE+Y+QI
Sbjct: 958 GRTFLRVLLHLIMHEYPALVSGALHLLFRHFSQRHEVLHAFRQVQLLVSDSDVESYKQIK 1017
Query: 3454 RDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEA 3633
DL +L+ EKSELWV+ +K+ D DL + + G+ +
Sbjct: 1018 SDLDVLRQSVEKSELWVY-------KSKQTD-------------DLLAGGGGEGGEGGDG 1057
Query: 3634 LMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTG 3813
E P + E Q Y I+Q+L+R+
Sbjct: 1058 SGGKGGEQGPELNPEQSQ----------------------------EYKKIQQILIRMNK 1089
Query: 3814 MCYRKGDP----KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRS 3981
+C P KP Q+LL+N+ V+ VVL+ + +P+D+K D+ M +L+ L+HEFL++
Sbjct: 1090 LCITATGPDGFVKPRKHEQRLLRNVGVHTVVLDLLQIPYDEKDDYRMNELMRLAHEFLQN 1149
Query: 3982 FCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHI 4161
FC N++NQ L+K + G+L ET+ AIF++N L + V ++++ H
Sbjct: 1150 FCLGNQQNQILLHK--QLDLFLNPGILEAETV------CAIFKDNLNLCNEVSDKVVQHF 1201
Query: 4162 VGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELE 4341
V IE + R+ +L+ LQ ++ ++ I Q+ V E+ A +EV Y D SF
Sbjct: 1202 VHCIEIHGRHVEYLKFLQTIIKAENQFIRKCQDMVMQELVNAGEEVLVFYNDKGSFNYFV 1261
Query: 4342 AMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTA 4521
+M+ S G +D L YHIELV+LLA CT GKN TE+KC S + +D IV +++
Sbjct: 1262 ELMR--SYSAGTLADP-SPLMYHIELVKLLACCTMGKNVYTEIKCNSLLALDDIVAMISH 1318
Query: 4522 KQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHIL-NNLLEDIRSLRVEKLTGAET 4698
C+ EVK Y+ L HCYIDT+ E+K+ Y + ++ + + L DI + V K
Sbjct: 1319 PDCIPEVKVAYVDFLCHCYIDTEVEVKEIYSSNHMWCLFEKSFLIDINN--VVKGGSFTN 1376
Query: 4699 ATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKS 4878
LE+Y+C+ V +L FF + +S A + + F ++L L + K G
Sbjct: 1377 KQLENYVCNEVMNILTTFFNSQFSDQSTA---LQKRQLIFVKILQNSFKLTQCK--GLTP 1431
Query: 4879 SRNWYRVAECIKRLTKWAEEHNITLPATLAGP--QMSGQTSVRQKWQQAASSAKWIGIGK 5052
S+ + V CI+ L++ A+ I +P L +M +T++ + ++KW+ + K
Sbjct: 1432 SQR-FNVENCIRTLSEKAKPRGIAIPIDLENQVVKMFNKTAMLSR-----QTSKWLLVTK 1485
>gi|50754604|ref|XP_414438.1| PREDICTED: similar to inositol
1,4,5-trisphosphate receptor type 1 [Gallus gallus]
Length = 3466
Score = 861 bits (2224), Expect = 0.0
Identities = 601/1696 (35%), Positives = 881/1696 (51%), Gaps = 128/1696 (7%)
Frame = +1
Query: 262 CLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGN 441
CLFK+CP+NRY+AQK W K +S D L+NKL AAD E+++NE+E +K LG
Sbjct: 743 CLFKLCPMNRYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGT 800
Query: 442 VIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIG 621
VIQYG+++QLLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +IG
Sbjct: 801 VIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIG 860
Query: 622 DNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLL 801
D+V G+K+ L P AG LH SS L+D+ EVN +N T W++ +F+
Sbjct: 861 DSVVIGDKVVLNP-----VNAGQ---PLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMK 912
Query: 802 FDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRAL 981
+ +N+ + +K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+AL
Sbjct: 913 WSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKAL 968
Query: 982 WEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNN 1161
WEV+VVQ + RGG WN +RFKHLAT YL+AE V P Y + +
Sbjct: 969 WEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAE-----VNPD---------YEEDDQ 1014
Query: 1162 PMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEV 1341
D + + Q+ + V P + D + +F+LDP+T + V
Sbjct: 1015 ECQSSQDPEQDASRRGLRSAQEKMAYSLVSVPEGN-----DISSIFELDPTTLRGGDSLV 1069
Query: 1342 PRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLPVN 1518
PR SYVRL H ++ WVH+TN + + EK +K+ + DKE FA++PV+
Sbjct: 1070 PRNSYVRLRHLCTNTWVHSTN------IPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVS 1123
Query: 1519 PDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPL 1698
P EVRDLDFANDA K L + ++ G + E S T+LL D + FVT ++ D L
Sbjct: 1124 PAEVRDLDFANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQDVL 1182
Query: 1699 KISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFK 1878
++ P+R+RQKL+REQ +L Q+F LL+APF T D R+ F+
Sbjct: 1183 EVVFSKPNRERQKLMREQNILKQIFKLLQAPF-----TDSGDGPMLRLEELGDQRHAPFR 1237
Query: 1879 TMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYV 2058
+ +LCY +E++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK++
Sbjct: 1238 HICRLCY-------------REYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHI 1284
Query: 2059 KTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKI 2238
++ FV LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++TK+
Sbjct: 1285 TAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPANADILIETKL 1344
Query: 2239 I------------DGEIEVG---------WAPNFRKLV-----DIAEGAKSNS-DDAEHL 2337
+ + +EVG W + +++ ++A+ AK +D + L
Sbjct: 1345 VLSRFEFEEVSSGENALEVGEDEEEVWLFWRDSNKEIRSKSIRELAQDAKEGQKEDRDVL 1404
Query: 2338 DYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFT 2517
YYR+QL+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR SF
Sbjct: 1405 SYYRYQLNLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRASFC 1456
Query: 2518 RLMLHLHVVRG--------------SPMSAI---------RHARLWWSIPENVNVSTYES 2628
RLMLH+HV R + SAI + W + Y+S
Sbjct: 1457 RLMLHMHVDRDPQEQSSDSSKLIVHTAASAINSRNKGKMQKQVMCWIQSCCLIANGNYDS 1516
Query: 2629 VSVEAYSDGSRMRIGEGIAHKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKAL 2808
S S+ I E A + + VE YL + Q +KLT+E+VNLA+ L
Sbjct: 1517 ------SGTSKDEIKERFA-QTMEFVEEYLRDVVCQRFPFSDK-EKNKLTFEVVNLARNL 1568
Query: 2809 AQFNFYSFNDLLQLTQNLLAIIN--------------EGPATEQVPSHRAMVNAIRNMSK 2946
F FY+F DLL+LT+ LLAI++ +G ++ R++ M++
Sbjct: 1569 IYFGFYNFCDLLRLTKILLAILDCVHITTIFPITKMAKGEESKGSNVMRSIHGVGELMTQ 1628
Query: 2947 SMMRGGNKENSKDLAKTPSVTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITM 3126
++RGG LA P ++ KE L + TKL + EILQF+++VR DYRI+
Sbjct: 1629 VVLRGGGFLPMTPLAAAPEGNVKQTEPEKED-ILVMDTKLKIIEILQFILNVRLDYRISC 1687
Query: 3127 ALSWFKNVFPCDEDGSLMHSA---SINERMASELYDAI---------------YRSSGHE 3252
L FK+ F DE + M + S ++ M + + A+ + S HE
Sbjct: 1688 LLCIFKHEF--DESNAQMSESPTGSSSQEMPANVPGALDFEHIEEQAEGIFGGRKVSLHE 1745
Query: 3253 ----LHLDGRDGQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQLLVS 3420
L LD G+ L +LL +TM DYPPL S AL++ FRHF+Q QE+L+ KQVQLLV+
Sbjct: 1746 ENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVT 1805
Query: 3421 NNDVENYRQIDRDLFILKNLTEKSELWVHGDRHHSIDTKEVDEKERTTEHDLLDHDLKSP 3600
+ DV+NY+QI +DL L+++ EKSELWV+ + + +D EH +
Sbjct: 1806 SQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQG---PDETMDGVPGENEHKKKEEG---- 1858
Query: 3601 RAFDSGDSMEALMAVLNEHYPSIRNECLQLLNRLLIKDDRNDAAVALQELSDKAPLIAYP 3780
H S + E N ++K+
Sbjct: 1859 ------------------HSKSQKPESTSSYNYRVVKE---------------------- 1878
Query: 3781 LIRQMLVRLTGMCYRKGDP--KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHD----- 3939
+L+RL+ +C ++ K Q+LL+NM + VVLE + +P++K + D
Sbjct: 1879 ----ILLRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKSWNWDSSSAH 1934
Query: 3940 ------------------------MMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDA 4047
M +++ L+HEFL++FC N++NQ+ L+K I+
Sbjct: 1935 LQVNLQILCNSIVFVMQSQAEDTRMQEIMKLAHEFLQNFCAGNQQNQALLHKHIN----- 1989
Query: 4048 KEGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVC 4227
+ I E T+ IF NN +L S + E ++ H V IE + RN +++ LQ +V
Sbjct: 1990 ---LFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVK 2046
Query: 4228 VYDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKY 4407
K I+ Q+ + N A ++V Y D ASF+ L MM+ E++ D L Y
Sbjct: 2047 AEGKFIKKCQDMLVN----AGEDVLVFYNDRASFQTLVQMMRSERD----RMDENSPLMY 2098
Query: 4408 HIELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDT 4587
HI LV LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT
Sbjct: 2099 HIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDT 2158
Query: 4588 DAEMKDAYKTEYVDHILNNLLEDI-RSLRVEKLTGAETATLEHYICHTVTEVLIKFFEAP 4764
+ EMK+ Y + ++ + N L DI R+ + LE Y+ V ++ FF +P
Sbjct: 2159 EVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSP 2218
Query: 4765 Y---SALQQAKVDVHHHKKTFSEVLLELTYLEKGKLRGSKSSRNWY------RVAECIKR 4917
+ S Q ++ + K+T V ++L +G R NW V CI+
Sbjct: 2219 FSDQSTTLQTQI-LTRIKETRQPVFVQLL---QGVFRVYHC--NWLMPSQKASVESCIRV 2272
Query: 4918 LTKWAEEHNITLPATL 4965
L+ A+ I +P L
Sbjct: 2273 LSDVAKSRAIAIPVDL 2288
Score = 68.2 bits (165), Expect = 2e-09
Identities = 36/76 (47%), Positives = 47/76 (61%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ + G +PPKKFR+ +
Sbjct: 324 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPEAGDLNNPPKKFREANAMQRRAD 379
Query: 289 RYAAQKHLWTEQKRFQ 336
A K W ++ F+
Sbjct: 380 AKGADKMQWKIKRNFK 395
>gi|47227347|emb|CAF96896.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2743
Score = 747 bits (1929), Expect = 0.0
Identities = 486/1232 (39%), Positives = 684/1232 (55%), Gaps = 99/1232 (8%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFRDCLFKVCPVN 288
LHIGDI SLY E ++ GF+STLGLVDDRC+V+ G +PPKKFRDCLF++CP+N
Sbjct: 9 LHIGDICSLYAEGTTC----GFISTLGLVDDRCVVQPDTGDLNNPPKKFRDCLFRLCPMN 64
Query: 289 RYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLGNVIQYGSMVQ 468
RY+AQK W K G+S D L+NKL AAD E+++NESE +K LG VIQYG+++Q
Sbjct: 65 RYSAQKQFWKAAK--PGGNSTTDAVLLNKLHHAADLEKKQNESENRKLLGTVIQYGNVIQ 122
Query: 469 LLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAIGDNVSAGNKI 648
LLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK ++GD+V G+K+
Sbjct: 123 LLHLKSNKYLTVNKRLPALLEKNAMRVTLDSAGNEGSWFYIQPFYKLRSLGDSVVIGDKV 182
Query: 649 SLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFLLFDENQQNSV 828
L P AG LH SS L+D+ EVN +N T W+V +F+ + +N++ +
Sbjct: 183 VLNP-----VNAGQ---PLHASSHQLVDNPGCNEVNSVNCNTSWKVVLFMKWSDNKETIL 234
Query: 829 KSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRALWEVQVVQTN 1008
K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+ALWEV+VV +
Sbjct: 235 KGGDVVRLFHAEQEKFLTCDDHRKKQ----YVFLRTTGRQSATSATSSKALWEVEVVHHD 290
Query: 1009 AYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTNNPMAMYSDGP 1188
RGG WN +RFKHLAT YL+AE +V P D
Sbjct: 291 PCRGGAGYWNSLFRFKHLATGCYLAAEVGEVV----------------DFTPFNFQLDAD 334
Query: 1189 NGVTNESTDTTQQNIPSVWVLGPTKSEFPEEDANLLFQLDPSTFMKSNKEVPRRSYVRLL 1368
N Q+ + ++ L P D + +F+LDP+T + VPR SYVRL
Sbjct: 335 NEALRGRLRAPQEKV--MYTLVPVPDGM---DISSIFELDPTTLRGGDSMVPRNSYVRLR 389
Query: 1369 HQSSDKWVHATNATEKQNLHYSSKNEKGWVKVI-CEKNRVDKETFALLPVNPDEVRDLDF 1545
H ++ WVH+T L + EK + +I + DKE FA++PV P EVRDLDF
Sbjct: 390 HLCTNTWVHSTV------LPIDKEEEKPVMLMIGTSAVKEDKEAFAIVPVPPAEVRDLDF 443
Query: 1546 ANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFSPSR 1725
ANDA K L + ++ G + E T+LL D + FV + + D L+I PSR
Sbjct: 444 ANDASKVLASIAGKLEKGTITQNER-RFVTKLLEDLVFFVVDIPNSGQDVLEIMVNKPSR 502
Query: 1726 DRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLCYCL 1905
+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LCY +
Sbjct: 503 ERQKLMREQNILKQIFKLLQAPF-----TDSGDGPMLRLEELGDQRHAPFRHICRLCYRV 557
Query: 1906 LKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVERFV 2085
L++SQ YRKNQ A++F +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++ FV
Sbjct: 558 LRHSQQDYRKNQA--AKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFV 615
Query: 2086 ELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIEVGW 2265
LVR NR+ +FLDYL+DLCV ++ QELIC +VL + DI ++TK++ E+
Sbjct: 616 TLVRKNREPRFLDYLSDLCVSMQKSIPVTQELICNAVLDPSNADILIETKLVLSRFEIET 675
Query: 2266 APN-------------------------FRKLVDIAEGAK-SNSDDAEHLDYYRHQLDLL 2367
A N + + ++A+ AK +D E + YYR QL+L
Sbjct: 676 ASNGESPVEAEDEEEVWLFWKDNCKEIRSKSIRELAQDAKEGQKEDLEVVSYYRCQLNLF 735
Query: 2368 SQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLHLHVVR 2547
++MC ++QYLAI+ IS QL +L+L+CMSD LP+DLR SF RLMLH+HV R
Sbjct: 736 ARMCLDRQYLAIN--------KISGQLDVDLILRCMSDEDLPFDLRASFCRLMLHMHVDR 787
Query: 2548 G--SPMSAIRHARLWWSIPENVNV-STYESVSVEAYSDG-SRMRIGEGIAHKVLATVETY 2715
++ +++ARLW IP + + +Y+ +DG +R I E + + VETY
Sbjct: 788 DPQEQVTPVKYARLWSEIPSKIAIDDSYD-------NDGTTRDEIKERFS-LTMDFVETY 839
Query: 2716 LMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAI-------- 2871
L + +Q++ +KLT+E+VNLA+ L F FY+F+DLL+LT+ LL I
Sbjct: 840 LREVVSQNVPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKVLLNILDCVHVST 898
Query: 2872 ---INEGPATEQVPSHRAM--VNAIRN-MSKSMMRGGNKENSKDLAKTPSVTAEEAGRTK 3033
IN+ E+ M ++ + M++ ++RGG + + + +
Sbjct: 899 IYPINKMEKEEENKGSNVMKSIHGVGELMTQVVLRGGGLLPTTPTHQPQGDVVKTQTEPE 958
Query: 3034 EGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDE-----DGS-------- 3174
+ + TKL + EILQF+++VR DYRI+ L FK+ F DE DG+
Sbjct: 959 REDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKHEF--DESNPQADGAAAQNGTNN 1016
Query: 3175 ---------------------------------------LMHSASINERMASELYDAIYR 3237
L+ +++ E + I+
Sbjct: 1017 VTSQMPGTMDRFDSRQSFNTVGEAMLIRCNFLLNLKKTLLISVGNLDFEKIEEQAEGIFG 1076
Query: 3238 SSGHELHLDGRD--GQLLLAILLQMTMSDYPPLTSIALKVFFRHFTQYQELLEDLKQVQL 3411
S LD D G+ L +LL +TM DYPPL S AL + FRHF+Q QE+L KQVQL
Sbjct: 1077 GSEENSPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALHLLFRHFSQRQEVLMAFKQVQL 1136
Query: 3412 LVSNNDVENYRQIDRDLFILKNLTEKSELWVH 3507
LV++ DV+NY+QI DL L+++ EKSELWV+
Sbjct: 1137 LVTSQDVDNYKQIKSDLDQLRSIVEKSELWVY 1168
Score = 185 bits (470), Expect = 9e-45
Identities = 123/353 (34%), Positives = 185/353 (51%), Gaps = 8/353 (2%)
Frame = +1
Query: 3931 DHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFR 4110
D M ++ L+HEFL++FC N++NQ L+K ++ + G+L T++ IF
Sbjct: 1214 DIRMQDIMKLAHEFLQNFCAGNQQNQVLLHKHVNLFLNP--GILEATTMQH------IFM 1265
Query: 4111 NNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAAS 4290
NN +L S + E ++ H V E + R+ +L+ LQ +V +K I+ Q+ V E+ +
Sbjct: 1266 NNFQLCSEINERVVQHFVHCTETHGRHVQYLKFLQTIVKAENKSIKKCQDIVMAEMVNSG 1325
Query: 4291 DEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYHIELVRLLAMCTRGKNGNTEL 4470
++V Y D ASF+ L MM+ E++ D L YHI LV LLA+CT GKN TE+
Sbjct: 1326 EDVLVFYNDRASFQTLIQMMRSERDRM----DENSPLLYHIHLVELLAVCTEGKNVYTEI 1381
Query: 4471 KCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDAEMKDAYKTEYVDHILNNLL 4650
KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+ EMK+ Y + ++ + N L
Sbjct: 1382 KCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTEVEMKEIYTSNHMWKLFENFL 1441
Query: 4651 EDIRSL--RVEKLTGAETATLEHYICHTVTEVLIKFFEAPYSALQQAKVDVHHHKKTFSE 4824
DI + A+T TLE Y+ TV ++ FF +P+S D +T
Sbjct: 1442 VDICRVCNNTSDRKHADT-TLERYVTETVMSIVTCFFSSPFS-------DQSTSLQTRQP 1493
Query: 4825 VLLELTYLEKGKLRGSKSSRNWYR------VAECIKRLTKWAEEHNITLPATL 4965
V ++L +G R NW V CIK L+ A+ I +P L
Sbjct: 1494 VFVQLL---QGVFRVYHC--NWLNPVQKASVEACIKVLSDVAKSRAIAIPVDL 1541
Score = 49.7 bits (117), Expect = 8e-04
Identities = 63/301 (20%), Positives = 119/301 (38%), Gaps = 48/301 (15%)
Frame = +1
Query: 3838 KPDTMNQQLLKNMRVYEVVLEFISVPHDKKHDHDMMKLITLS---HEFLRSFCKT----- 3993
KP Q+L++ + + + + + P D M++L L H R C+
Sbjct: 499 KPSRERQKLMREQNILKQIFKLLQAPFTDSGDGPMLRLEELGDQRHAPFRHICRLCYRVL 558
Query: 3994 -------NKENQSRLYKFISYEKDAKEGMLRVETIEEVGTLVAIFRNNRELAS-NVPEEL 4149
K ++ ++F+ +K +L +TI A+ NNR+L ++
Sbjct: 559 RHSQQDYRKNQAAKQFRFM--QKQIGYDVLAEDTI------TALLHNNRKLLEKHITAAE 610
Query: 4150 IAHIVGLIEHNSRNPIFLELLQALVCVYDKEIESGQEKVANEICAASDE---------VR 4302
I V L+ N R P FL+ L L K I QE + N + S+ +
Sbjct: 611 IDTFVTLVRKN-REPRFLDYLSDLCVSMQKSIPVTQELICNAVLDPSNADILIETKLVLS 669
Query: 4303 QLYVDNASFEELEAMMKDE-----------KESKGRS-----SDSRRKLKYHIELV---- 4422
+ ++ AS E +DE KE + +S D++ K +E+V
Sbjct: 670 RFEIETASNGESPVEAEDEEEVWLFWKDNCKEIRSKSIRELAQDAKEGQKEDLEVVSYYR 729
Query: 4423 ---RLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTDA 4593
L A + K + Q+ +D I+R ++ + +++ + +L+LH ++D D
Sbjct: 730 CQLNLFARMCLDRQYLAINKISGQLDVDLILRCMSDEDLPFDLRASFCRLMLHMHVDRDP 789
Query: 4594 E 4596
+
Sbjct: 790 Q 790
>gi|26339686|dbj|BAC33514.1| unnamed protein product [Mus musculus]
Length = 1004
Score = 658 bits (1697), Expect = 0.0
Identities = 413/1017 (40%), Positives = 591/1017 (57%), Gaps = 45/1017 (4%)
Frame = +1
Query: 259 DCLFKVCPVNRYAAQKHLWTEQKRFQTGDSMFDDDLMNKLKVAADKEREENESEFQKTLG 438
DCLFK+CP+NRY+AQK W K +S D L+NKL AAD E+++NE+E +K LG
Sbjct: 5 DCLFKLCPMNRYSAQKQFWKAAK--PGANSTTDAVLLNKLHHAADLEKKQNETENRKLLG 62
Query: 439 NVIQYGSMVQLLHVKSNKYITVQKNSPAKRERNAMKVYLDRAGNEGSWFIIEPAYKHYAI 618
VIQYG+++QLLH+KSNKY+TV K PA E+NAM+V LD AGNEGSWF I+P YK +I
Sbjct: 63 TVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSI 122
Query: 619 GDNVSAGNKISLIPNSVSTTQAGHVKSQLHLSSFNLLDHQSAAEVNCLNEPTEWQVFMFL 798
GD+V G+K+ L P AG LH SS L+D+ EVN +N T W++ +F+
Sbjct: 123 GDSVVIGDKVVLNP-----VNAG---QPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFM 174
Query: 799 LFDENQQNSVKSGDVVRLFHADQQTFLTLDTIPKQNPPTDVVFLRMTNRPSAADATSSRA 978
+ +N+ + +K GDVVRLFHA+Q+ FLT D K+ VFLR T R SA ATSS+A
Sbjct: 175 KWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQH----VFLRTTGRQSATSATSSKA 230
Query: 979 LWEVQVVQTNAYRGGTAKWNKAYRFKHLATDMYLSAEPSQVQVKPAMNGRRASLIYSKTN 1158
LWEV+VVQ + RGG WN +RFKHLAT YL+AE V P + L + +
Sbjct: 231 LWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAE-----VDP--DFEEECLEFQPSV 283
Query: 1159 NPMAMYSDGPNGVTNESTDTTQQNIPSVWVLGPTKSEFPE-EDANLLFQLDPSTFMKSNK 1335
+P D + + ++ SV PE D + +F+LDP+T +
Sbjct: 284 DP---DQDASRSRLRNAQEKMVYSLVSV----------PEGNDISSIFELDPTTLRGGDS 330
Query: 1336 EVPRRSYVRLLHQSSDKWVHATNATEKQNLHYSSKNEKG-WVKVICEKNRVDKETFALLP 1512
VPR SYVRL H ++ WVH+T N+ + EK +K+ + DKE FA++P
Sbjct: 331 LVPRNSYVRLRHLCTNTWVHST------NIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVP 384
Query: 1513 VNPDEVRDLDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLAD 1692
V+P EVRDLDFANDA K L + ++ G + E S T+LL D + FVT ++ D
Sbjct: 385 VSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNER-RSVTKLLEDLVYFVTGGTNSGQD 443
Query: 1693 PLKISDFSPSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEI 1872
L++ P+R+RQKL+REQ +L Q+F LL+APF T D R+
Sbjct: 444 VLEVVFSKPNRERQKLMREQNILKQIFKLLQAPF-----TDCGDGPMLRLEELGDQRHAP 498
Query: 1873 FKTMFQLCYCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEK 2052
F+ + +LCY +L++SQ YRKNQE++A++FG +Q+QIG+D++AEDT+TA+LHNN KLLEK
Sbjct: 499 FRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEK 558
Query: 2053 YVKTPHVERFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDT 2232
++ ++ FV LVR NR+ +FLDYL+DLCV ++ QELIC +VL+ + DI ++T
Sbjct: 559 HITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIET 618
Query: 2233 KII---------------------DGEIEVGWAPNFRKL-----VDIAEGAK-SNSDDAE 2331
K++ + E+ + W + +++ ++A+ AK +D +
Sbjct: 619 KLVLSRFEFEGVSTGENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRD 678
Query: 2332 HLDYYRHQLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGS 2511
L YYR+QL+L ++MC ++QYLAI+ IS QL +L+L+CMSD LPYDLR S
Sbjct: 679 ILSYYRYQLNLFARMCLDRQYLAIN--------EISGQLDVDLILRCMSDENLPYDLRAS 730
Query: 2512 FTRLMLHLHVVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDGSRMRIGEGIA 2685
F RLMLH+HV R ++ +++ARLW IP + + Y+S S S+ I E A
Sbjct: 731 FCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDS------SGTSKDEIKERFA 784
Query: 2686 HKVLATVETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLL 2865
+ + VE YL + Q +KLT+E+VNLA+ L F FY+F+DLL+LT+ LL
Sbjct: 785 -QTMEFVEEYLRDVVCQRFPFSDK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILL 842
Query: 2866 AIINEGPATEQVPSHRAM-------VNAIRN-------MSKSMMRGGNKENSKDLAKTPS 3003
AI++ T P + N +R+ M++ ++RGG +A P
Sbjct: 843 AILDCVHVTTIFPISKMTKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPE 902
Query: 3004 VTAEEAGRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGS 3174
++A KE + + TKL + EILQF+++VR DYRI+ L FK F DE S
Sbjct: 903 GNVKQAEPEKED-IMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREF--DESNS 956
>gi|47229530|emb|CAG06726.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 2336
Score = 640 bits (1652), Expect = 0.0
Identities = 437/1271 (34%), Positives = 666/1271 (52%), Gaps = 71/1271 (5%)
Frame = +1
Query: 1366 LHQSSDKWVHATNATE---KQNLHYSSKNEKGWVKVICEKNRVDKETFALLPVNPDEVRD 1536
LH S+ + V E + H SK +GW +C PV+P EVRD
Sbjct: 134 LHASTHQLVDNPGCNEGLSATDRHLCSKRGQGWPLPLC-------------PVSPAEVRD 180
Query: 1537 LDFANDACKALRNFIKLIKIGQVISKESINSTTQLLIDCILFVTNSSDHLADPLKISDFS 1716
LDFANDA K L + ++ G + E + T+LL D + FV + + D L+I
Sbjct: 181 LDFANDASKVLASIAGKLEKGTITQNER-RAVTKLLEDLVFFVVDIPNSGQDVLEIMVNK 239
Query: 1717 PSRDRQKLLREQEVLNQVFLLLKAPFLPRQGTTXXXXXXXXXXXXXDSRNEIFKTMFQLC 1896
P+R+RQKL+REQ +L Q+F LL+APF T D R+ F+ + +LC
Sbjct: 240 PNRERQKLMREQNILKQIFKLLQAPF-----TDSGDGPMLRLEELADQRHAPFRHICRLC 294
Query: 1897 YCLLKYSQVSYRKNQEFLAEKFGEIQEQIGFDLMAEDTMTAVLHNNPKLLEKYVKTPHVE 2076
Y +L++SQ YRKNQE++A++F +Q+QIG+D++AEDT+TA+LHNN KLLEK++ ++
Sbjct: 295 YRVLRHSQQDYRKNQEYIAKQFRFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEID 354
Query: 2077 RFVELVRNNRQGKFLDYLADLCVCRGEANKKIQELICTSVLSSKHRDIFMDTKIIDGEIE 2256
FV LVR NR+ +FLDYL+DLCV ++ QELIC +VL + DI ++TK++ E
Sbjct: 355 TFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICNAVLDPANADILIETKLVLSRFE 414
Query: 2257 VGWAP---------------------------NFRKLVDIAEGAKSNS-DDAEHLDYYRH 2352
+ AP + + ++A+ AK +D E + YYR+
Sbjct: 415 IEGAPLGENSLESEEDEEEVWLFWKDNNNKEIRSKSIRELAQDAKEGQKEDQEVISYYRY 474
Query: 2353 QLDLLSQMCQEQQYLAIDPPPERRLMNISQQLPAELVLQCMSDNRLPYDLRGSFTRLMLH 2532
QL+L ++MC ++QYLAI+ IS QL +L+L+CMSD LP+DLR SF R+MLH
Sbjct: 475 QLNLFARMCLDRQYLAIN--------KISGQLDVDLILRCMSDEDLPFDLRASFCRMMLH 526
Query: 2533 LHVVRG--SPMSAIRHARLWWSIPENVNVSTYESVSVEAYSDG-SRMRIGEGIAHKVLAT 2703
+HV R ++ +++ARLW IP + + Y++ DG S+ I E + + +
Sbjct: 527 MHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDN-------DGTSKDEIKERFS-QTMEF 578
Query: 2704 VETYLMGLRNQSMEERQSVNSSKLTYEIVNLAKALAQFNFYSFNDLLQLTQNLLAIIN-- 2877
VE YL + QS +KLT+E+VNLA+ L F FY+F+DLL+LT+ LLAI++
Sbjct: 579 VENYLRDVVCQSFPFADK-EKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCV 637
Query: 2878 ------------EGPATEQVPSHRAMVNAIRNMSKSMMRGGNKENSKDLAKTPSVTAEEA 3021
+ ++ R++ MS+ ++RGG T T +
Sbjct: 638 HIGTAFGFNKLDKDDESKGSNVMRSIHGVGELMSQVVLRGGGFLPMTPSISTSRDTVKTQ 697
Query: 3022 GRTKEGRALNVKTKLIVAEILQFVMDVRRDYRITMALSWFKNVFPCDEDGSLMH------ 3183
++ L + TKL + EILQF+++VR DYRI+ LS FK F DE S
Sbjct: 698 TEPEKQDILVMDTKLKIIEILQFILNVRLDYRISCLLSIFKREF--DESNSQSELPVGGA 755
Query: 3184 -------SASINERMASELYDAIYRSSGHE--LHLDGRDGQLLLAILLQMTMSDYPPLTS 3336
+++ E + I+ S L LD G+ L +LL +TM DYPPL S
Sbjct: 756 VEGPNNMPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVS 815
Query: 3337 IALKVFFRHFTQYQELLEDLKQVQLLVSNNDVENYRQIDRDLFILKNLTEKSELWVHGDR 3516
AL + FRHF+Q QE+L+ KQVQLLV++ DVENY+QI DL L+++ EKSELWV+
Sbjct: 816 RALHLLFRHFSQRQEVLQAFKQVQLLVTSQDVENYKQIKSDLDQLRSIVEKSELWVY--- 872
Query: 3517 HHSIDTKEVDEKERTTEHDLLDHDLKSPRAFDSGDSMEALMAVLNEHYPSIRNECLQLLN 3696
K + +E + D+G+ + C + +
Sbjct: 873 -----------KRQGSEEGM-----------DTGEGL-----------------CAEPEH 893
Query: 3697 RLLIKDDRNDAAVALQELSDKAPLIAYPLIRQMLVRLTGMCYRKG--DPKPDTMNQQLLK 3870
+L+ + + ++ + + Y +++++L+RL+ +C ++G K Q+LL+
Sbjct: 894 KLVPYFENSLSSKYKTKKPESTSSYNYRVVKEILLRLSKLCVQEGLSGRKSKKQQQRLLR 953
Query: 3871 NMRVYEVVLEFISVPHDKKHDHDMMKLITLSHEFLRSFCKTNKENQSRLYKFISYEKDAK 4050
NM + VVLE + +P++K D M ++ L+H+FL++FC N++NQ+ L+K I+
Sbjct: 954 NMGAHSVVLELLQIPYEKGEDLRMQDIMKLAHQFLQNFCAGNQQNQALLHKHIN------ 1007
Query: 4051 EGMLRVETIEEVGTLVAIFRNNRELASNVPEELIAHIVGLIEHNSRNPIFLELLQALVCV 4230
+ I E T+ IF NN +L S + E ++ H V IE + RN +L+ LQ +V
Sbjct: 1008 --LFLNPGILEAITMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYLKFLQTIVKA 1065
Query: 4231 YDKEIESGQEKVANEICAASDEVRQLYVDNASFEELEAMMKDEKESKGRSSDSRRKLKYH 4410
+K I+ Q+ V E+ A ++V Y D ASF+ L MM+ E++ D L YH
Sbjct: 1066 ENKFIKKCQDIVMAELVNAGEDVLVFYNDRASFQTLVQMMRSERD----RMDENSPLMYH 1121
Query: 4411 IELVRLLAMCTRGKNGNTELKCASQIPMDHIVRVVTAKQCLVEVKTVYLQLLLHCYIDTD 4590
I LV LLA+CT GKN TE+KC S +P+D IVRVVT + C+ EVK Y+ L HCY+DT+
Sbjct: 1122 IHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDTE 1181
Query: 4591 AEMKDAYKTEYVDHILNNLLEDIRSLRVEKLTG----AETATLEHYICHTVTEVLIKFFE 4758
EMK+ Y + ++ + N L DI RV T A+T LE Y+ TV ++ FF
Sbjct: 1182 VEMKEIYTSNHMWKLFENFLVDI--CRVCNSTSDRKHADT-ILERYVTETVMSIVTTFFS 1238
Query: 4759 APYSALQQAKVDVHHHKKTFSEVLLEL--TYLEKGKLRGSKSSRNWYRVAECIKRLTKWA 4932
+P+S + + F ++L + Y + K S V CIK L+ A
Sbjct: 1239 SPFS---DQSTSLQTRQPVFVQLLQAVFRVYHCNWLIPVQKGS-----VENCIKVLSDVA 1290
Query: 4933 EEHNITLPATL 4965
+ I +P L
Sbjct: 1291 KGRAIAIPVDL 1301
Score = 63.9 bits (154), Expect = 4e-08
Identities = 32/50 (64%), Positives = 37/50 (74%)
Frame = +1
Query: 109 LHIGDIISLYTESSSNQEQRGFLSTLGLVDDRCIVELKDGRPESPPKKFR 258
LHIGDI SLY E S+N GF+STLGLVDDRC+V+ G +PPKKFR
Sbjct: 9 LHIGDICSLYAEGSTN----GFISTLGLVDDRCVVQPDAGDLNNPPKKFR 54