Homology by BLASTX
BLASTX 2.2.4 [Aug-26-2002]
Query= F08B4_7
(2436 letters)
Database: /home/niguts/usr02/tshini/ykclst/db/nr.seq
1,967,186 sequences; 661,712,633 total letters
Score E
Sequences producing significant alignments: (bits) Value
gi|7498603|pir||T29486 hypothetical protein F08B4.6 - Caenorhabd... 1646 0.0
gi|14587788|dbj|BAB61756.1| N-deactylase/N-sulfotransferase [Cae... 1576 0.0
gi|25152478|ref|NP_501491.2| heparan SulphoTransferase, N-deacet... 1576 0.0
gi|14587790|dbj|BAB61757.1| N-deacetylase/N-sulfotransferase [Ca... 1576 0.0
gi|27374524|gb|AAB37730.3| Heparan sulphotransferase protein 1 [... 1482 0.0
gi|14587792|dbj|BAB61758.1| N-deacetylase/N-sulfotransferase [Ca... 1440 0.0
gi|39580996|emb|CAE72477.1| Hypothetical protein CBG19653 [Caeno... 1327 0.0
gi|31217059|ref|XP_316354.1| ENSANGP00000013790 [Anopheles gambi... 684 0.0
gi|13242253|ref|NP_077337.1| N-deacetylase/N-sulfotransferase (h... 683 0.0
gi|348494|pir||A42855 N-heparan sulfate sulfotransferase - rat 683 0.0
gi|31217052|ref|XP_316352.1| ENSANGP00000004205 [Anopheles gambi... 683 0.0
gi|42734444|ref|NP_032332.2| N-deacetylase/N-sulfotransferase (h... 682 0.0
gi|3136148|gb|AAC17228.1| heparan sulfate glucosaminyl N-deacety... 682 0.0
gi|5668903|gb|AAD46061.1| heparan N-deacetylase/N-sulfotransfera... 681 0.0
gi|4758766|ref|NP_004775.1| N-deacetylase/N-sulfotransferase (he... 681 0.0
gi|49118699|gb|AAH72733.1| Unknown (protein for MGC:79080) [Xeno... 679 0.0
gi|4505351|ref|NP_001534.1| N-deacetylase/N-sulfotransferase (he... 679 0.0
gi|12000419|ref|NP_072087.1| N-deacetylase/N-sulfotransferase (h... 678 0.0
gi|841164|gb|AAA67765.1| heparan sulfate N-deacetylase/N-sulfotr... 676 0.0
gi|17736971|ref|NP_523946.1| CG8339-PA [Drosophila melanogaster]... 675 0.0
gi|12007650|ref|NP_072091.1| N-deacetylase/N-sulfotransferase (h... 674 0.0
gi|4505353|ref|NP_003626.1| N-deacetylase/N-sulfotransferase (he... 668 0.0
gi|13626042|ref|NP_112463.1| N-deacetylase/N-sulfotransferase (h... 667 0.0
gi|47215555|emb|CAG06285.1| unnamed protein product [Tetraodon n... 665 0.0
gi|7106357|ref|NP_034941.1| N-deacetylase/N-sulfotransferase (he... 663 0.0
gi|27807493|ref|NP_777202.1| N-deacetylase/N-sulfotransferase (h... 662 0.0
gi|1708324|sp|P52850|HSS2_MOUSE Heparin sulfate N-deacetylase/N-... 661 0.0
gi|48132166|ref|XP_396688.1| similar to ENSANGP00000013790 [Apis... 617 e-175
gi|34868948|ref|XP_223793.2| N-deacetylase/N-sulfotransferase (h... 614 e-174
gi|50746753|ref|XP_420638.1| PREDICTED: similar to N-deacetylase... 547 e-154
gi|50755033|ref|XP_414592.1| PREDICTED: similar to Heparan sulfa... 504 e-141
gi|12854231|dbj|BAB29967.1| unnamed protein product [Mus musculus] 464 e-129
gi|47212790|emb|CAF93152.1| unnamed protein product [Tetraodon n... 433 e-120
gi|47212788|emb|CAF93150.1| unnamed protein product [Tetraodon n... 405 e-111
gi|50749384|ref|XP_421613.1| PREDICTED: similar to Heparin sulfa... 375 e-102
gi|15277597|gb|AAH12888.1| NDST1 protein [Homo sapiens] 363 8e-99
gi|50746879|ref|XP_426325.1| PREDICTED: similar to N-deacetylase... 358 4e-97
gi|47211601|emb|CAF94537.1| unnamed protein product [Tetraodon n... 354 6e-96
gi|34859973|ref|XP_342337.1| similar to N-deacetylase/N-sulfotra... 329 2e-88
gi|26330812|dbj|BAC29136.1| unnamed protein product [Mus musculus] 304 6e-81
gi|47208814|emb|CAF91186.1| unnamed protein product [Tetraodon n... 295 3e-78
gi|6137498|pdb|1NST|A Chain A, The Sulfotransferase Domain Of Hu... 275 5e-72
gi|47200399|emb|CAF88026.1| unnamed protein product [Tetraodon n... 272 2e-71
gi|47208353|emb|CAF91189.1| unnamed protein product [Tetraodon n... 271 7e-71
gi|34860221|ref|XP_227665.2| similar to heparan sulfate N-deacet... 266 2e-69
gi|34860229|ref|XP_345288.1| similar to N-deacetylase/N-sulfotra... 227 1e-57
gi|50755031|ref|XP_414591.1| PREDICTED: similar to N-deacetylase... 167 8e-40
gi|37182822|gb|AAQ89211.1| HSS3 [Homo sapiens] 145 6e-33
gi|34860227|ref|XP_227729.2| similar to N-deacetylase/N-sulfotra... 139 3e-31
gi|50749625|ref|XP_421692.1| PREDICTED: similar to heparan sulfa... 139 4e-31
gi|38090456|ref|XP_356462.1| similar to heparan sulfate (glucosa... 129 4e-28
gi|50744932|ref|XP_426178.1| PREDICTED: similar to heparan sulfa... 127 1e-27
gi|34852866|ref|XP_228219.2| similar to heparan sulfate (glucosa... 127 1e-27
gi|47221682|emb|CAG10154.1| unnamed protein product [Tetraodon n... 127 1e-27
gi|45267824|ref|NP_705840.2| heparan sulfate (glucosamine) 3-O-s... 127 1e-27
gi|31216423|ref|XP_316229.1| ENSANGP00000017049 [Anopheles gambi... 124 8e-27
gi|47221519|emb|CAG08181.1| unnamed protein product [Tetraodon n... 123 2e-26
gi|47213588|emb|CAF93491.1| unnamed protein product [Tetraodon n... 123 2e-26
gi|48116750|ref|XP_396407.1| similar to ENSANGP00000017049 [Apis... 122 5e-26
gi|6754246|ref|NP_034604.1| heparan sulfate (glucosamine) 3-O-su... 121 7e-26
gi|49259591|pdb|1VKJ|A Chain A, Crystal Structure Of Heparan Sul... 121 7e-26
gi|34785943|gb|AAH57803.1| Heparan sulfate D-glucosaminyl 3-O-su... 121 9e-26
gi|4826764|ref|NP_005105.1| heparan sulfate D-glucosaminyl 3-O-s... 121 9e-26
gi|25742834|ref|NP_445843.1| heparan sulfate (glucosamine) 3-O-s... 121 9e-26
gi|50747210|ref|XP_420786.1| PREDICTED: similar to heparan sulfa... 120 2e-25
gi|21739862|emb|CAD38957.1| hypothetical protein [Homo sapiens] 119 3e-25
gi|37541409|ref|XP_056254.5| heparan sulfate (glucosamine) 3-O-s... 119 3e-25
gi|48427667|ref|NP_006031.1| heparan sulfate D-glucosaminyl 3-O-... 118 8e-25
gi|5174465|ref|NP_006033.1| heparan sulfate D-glucosaminyl 3-O-s... 116 2e-24
gi|5174467|ref|NP_006032.1| heparan sulfate D-glucosaminyl 3-O-s... 116 2e-24
gi|14494990|emb|CAC42157.1| c439A6.1 (novel protein similar to h... 116 2e-24
gi|49522131|gb|AAH75183.1| LOC398971 protein [Xenopus laevis] 115 4e-24
gi|30725857|ref|NP_849201.1| heparan sulfate (glucosamine) 3-O-s... 115 5e-24
gi|31203455|ref|XP_310676.1| ENSANGP00000020804 [Anopheles gambi... 115 5e-24
gi|34871114|ref|XP_220226.2| similar to c439A6.1 (novel protein ... 115 5e-24
gi|48125807|ref|XP_396584.1| similar to CG7890-PA [Apis mellifera] 115 5e-24
gi|14336772|gb|AAK61299.1| heparan sulphate D-glucosaminyl 3-O-s... 115 5e-24
gi|9055264|ref|NP_061275.1| D-glycosaminyl 3-O-sulfotransferase-... 115 5e-24
gi|47215396|emb|CAG01093.1| unnamed protein product [Tetraodon n... 114 8e-24
gi|47218044|emb|CAG11449.1| unnamed protein product [Tetraodon n... 114 8e-24
gi|39645615|gb|AAH63731.1| MGC68516 protein [Xenopus laevis] 114 1e-23
gi|24643211|ref|NP_573370.1| CG7890-PA [Drosophila melanogaster]... 113 2e-23
gi|50757659|ref|XP_415596.1| PREDICTED: similar to COX10 homolog... 112 3e-23
gi|5174463|ref|NP_006034.1| heparan sulfate D-glucosaminyl 3-O-... 111 7e-23
gi|31077134|ref|NP_852035.1| heparan sulfate (glucosamine) 3-O-s... 111 9e-23
gi|48892081|ref|ZP_00325493.1| COG0457: FOG: TPR repeat [Trichod... 105 5e-21
gi|48891084|ref|ZP_00324658.1| COG0457: FOG: TPR repeat [Trichod... 103 3e-20
gi|39597028|emb|CAE59255.1| Hypothetical protein CBG02583 [Caeno... 102 6e-20
gi|17533853|ref|NP_495230.1| predicted CDS, heparan SulphoTransf... 101 1e-19
gi|48892084|ref|ZP_00325496.1| COG0457: FOG: TPR repeat [Trichod... 99 4e-19
gi|48892086|ref|ZP_00325498.1| COG0457: FOG: TPR repeat [Trichod... 99 4e-19
gi|47225943|emb|CAG04317.1| unnamed protein product [Tetraodon n... 98 1e-18
gi|37544641|gb|AAM50089.1| heparan sulfate 3-O-sulfotransferase ... 97 1e-18
gi|28189595|dbj|BAC56412.1| similar to heparin/heparan sulfate N... 95 7e-18
gi|48892619|ref|ZP_00325970.1| hypothetical protein Tery02004031... 95 9e-18
gi|28189188|dbj|BAC56285.1| similar to heparin/heparan sulfate N... 91 1e-16
gi|39591035|emb|CAE58815.1| Hypothetical protein CBG02023 [Caeno... 91 1e-16
gi|48891083|ref|ZP_00324657.1| COG0457: FOG: TPR repeat [Trichod... 89 4e-16
gi|46105888|ref|ZP_00186280.2| hypothetical protein Rxyl022543 [... 89 6e-16
gi|47220073|emb|CAG12221.1| unnamed protein product [Tetraodon n... 88 1e-15
gi|37542211|ref|XP_292562.3| similar to c439A6.1 (novel protein ... 88 1e-15
gi|38087497|ref|XP_357782.1| similar to hypothetical protein [Mu... 88 1e-15
gi|50755845|ref|XP_425248.1| PREDICTED: similar to hypothetical ... 87 2e-15
gi|34871576|ref|XP_343912.1| similar to D-glycosaminyl 3-O-sulfo... 85 7e-15
gi|34871566|ref|XP_220557.2| similar to D-glycosaminyl 3-O-sulfo... 85 7e-15
gi|33864619|ref|NP_896178.1| putative deacetylase sulfotransfera... 85 9e-15
gi|50755835|ref|XP_425243.1| PREDICTED: similar to heparan sulfa... 82 5e-14
gi|50757661|ref|XP_415597.1| PREDICTED: similar to heparan sulfa... 82 6e-14
gi|47220661|emb|CAG06583.1| unnamed protein product [Tetraodon n... 82 8e-14
gi|47220659|emb|CAG06581.1| unnamed protein product [Tetraodon n... 82 8e-14
gi|48891082|ref|ZP_00324656.1| COG0457: FOG: TPR repeat [Trichod... 81 1e-13
gi|20344103|ref|XP_112440.1| similar to heparan sulfate (glucosa... 79 4e-13
gi|28573557|ref|NP_788409.1| CG33147-PA [Drosophila melanogaster... 79 4e-13
gi|45523357|ref|ZP_00174728.1| COG0581: ABC-type phosphate trans... 78 9e-13
gi|21749358|dbj|BAC03577.1| unnamed protein product [Homo sapiens] 78 1e-12
gi|50755745|ref|XP_414882.1| PREDICTED: similar to heparan sulfa... 77 1e-12
gi|5441573|emb|CAB46836.1| heparan sulfate 3-O-sulfotransferase-... 74 1e-11
gi|16264495|ref|NP_437287.1| putative sulfotransferase protein [... 63 4e-08
gi|45545652|ref|ZP_00185787.1| hypothetical protein Rxyl022996 [... 61 1e-07
gi|37521762|ref|NP_925139.1| unknown protein [Gloeobacter violac... 61 1e-07
gi|33864928|ref|NP_896487.1| putative sulfotransferase protein [... 59 7e-07
gi|37520033|ref|NP_923410.1| unknown protein [Gloeobacter violac... 58 1e-06
gi|26328111|dbj|BAC27796.1| unnamed protein product [Mus musculus] 54 1e-05
gi|37520034|ref|NP_923411.1| unknown protein [Gloeobacter violac... 50 3e-04
gi|559647|gb|AAA50788.1| ORF3 49 6e-04
gi|47214557|emb|CAF96230.1| unnamed protein product [Tetraodon n... 47 0.002
gi|48891681|ref|ZP_00325164.1| COG0419: ATPase involved in DNA r... 46 0.004
gi|47220074|emb|CAG12222.1| unnamed protein product [Tetraodon n... 45 0.011
gi|48890923|ref|ZP_00324520.1| COG0699: Predicted GTPases (dynam... 42 0.069
gi|50809319|ref|XP_429013.1| PREDICTED: similar to heparan sulfa... 42 0.090
gi|47214556|emb|CAF96229.1| unnamed protein product [Tetraodon n... 41 0.12
gi|27679742|ref|XP_219303.1| similar to hypothetical protein [Ra... 40 0.20
gi|47226093|emb|CAG04467.1| unnamed protein product [Tetraodon n... 40 0.26
gi|34871572|ref|XP_220563.2| similar to heparan sulfate D-glucos... 40 0.34
gi|45527443|ref|ZP_00178643.1| hypothetical protein Cwat087901 [... 39 0.58
gi|29243922|ref|NP_808243.1| hypothetical protein A830061E14 [Mu... 39 0.58
gi|28498760|ref|XP_283407.1| similar to heparan sulphate D-gluco... 39 0.76
gi|20560099|gb|AAM27841.1| ORF_15; similar to Glycosyl transfera... 38 1.00
gi|20807056|ref|NP_622227.1| predicted acetyltransferases and hy... 37 2.2
gi|32044391|ref|ZP_00141492.1| COG0225: Peptide methionine sulfo... 36 4.9
gi|15600211|ref|NP_253705.1| peptide methionine sulfoxide reduct... 36 4.9
gi|46191893|ref|ZP_00007736.2| COG1429: Cobalamin biosynthesis p... 36 4.9
gi|49078722|gb|AAT49813.1| PA5018 [synthetic construct] 36 4.9
gi|15921233|ref|NP_376902.1| 264aa long conserved hypothetical p... 35 6.5
gi|8393684|ref|NP_058576.1| keratin, hair, acidic, 5; hair kerat... 35 8.4
gi|44004403|ref|NP_982071.1| conserved hypothetical protein [Bac... 35 8.4
gi|34911648|ref|NP_917171.1| P0039G05.27 [Oryza sativa (japonica... 35 8.4
>gi|7498603|pir||T29486 hypothetical protein F08B4.6 - Caenorhabditis
elegans
Length = 819
Score = 1646 bits (4262), Expect = 0.0
Identities = 802/819 (97%), Positives = 802/819 (97%), Gaps = 8/819 (0%)
Frame = -1
Query: 2436 MDFSVNFLIFDLYMLIFQQFEXXXXXXXXXTCGKLHVSVCKNRGHCQHGKTIIQILNSQK 2257
MDFSVNFLIFDLYMLIFQQFE TCGKLHVSVCKNRGHCQHGKTIIQILNSQK
Sbjct: 1 MDFSVNFLIFDLYMLIFQQFEATKTKKKAKTCGKLHVSVCKNRGHCQHGKTIIQILNSQK 60
Query: 2256 LQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLDKYCKEYRVPMFSFM 2077
LQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLDKYCKEYRVPMFSFM
Sbjct: 61 LQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLDKYCKEYRVPMFSFM 120
Query: 2076 SSKPNDQLKRIKIK--------GSSLWMWQNQRIQRLAVTPSIIHRISKIGNYRQFSSSD 1921
SSKPNDQLKRIKIK GSSLWMWQNQRIQRLAVTPSIIHRISKIGNYRQFSSSD
Sbjct: 121 SSKPNDQLKRIKIKVRFSGFTKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYRQFSSSD 180
Query: 1920 PADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLD 1741
PADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLD
Sbjct: 181 PADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLD 240
Query: 1740 ALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFML 1561
ALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFML
Sbjct: 241 ALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFML 300
Query: 1560 GFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQ 1381
GFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQ
Sbjct: 301 GFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQ 360
Query: 1380 NMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAG 1201
NMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAG
Sbjct: 361 NMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAG 420
Query: 1200 IHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDR 1021
IHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDR
Sbjct: 421 IHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDR 480
Query: 1020 LALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPP 841
LALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPP
Sbjct: 481 LALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPP 540
Query: 840 SINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGV 661
SINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGV
Sbjct: 541 SINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGV 600
Query: 660 EWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILA 481
EWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILA
Sbjct: 601 EWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILA 660
Query: 480 HEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDEL 301
HEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDEL
Sbjct: 661 HEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDEL 720
Query: 300 KMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKYPEMPEN 121
KMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKYPEMPEN
Sbjct: 721 KMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKYPEMPEN 780
Query: 120 LRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 4
LRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA
Sbjct: 781 LRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 819
>gi|14587788|dbj|BAB61756.1| N-deactylase/N-sulfotransferase
[Caenorhabditis elegans]
Length = 826
Score = 1576 bits (4082), Expect(2) = 0.0
Identities = 764/765 (99%), Positives = 765/765 (99%)
Frame = -1
Query: 2298 QHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
+HGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD
Sbjct: 62 RHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 121
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 1939
KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR
Sbjct: 122 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 181
Query: 1938 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 1759
QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV
Sbjct: 182 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 241
Query: 1758 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 1579
KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ
Sbjct: 242 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 301
Query: 1578 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 1399
NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ
Sbjct: 302 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 361
Query: 1398 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 1219
NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK
Sbjct: 362 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 421
Query: 1218 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 1039
GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ
Sbjct: 422 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 481
Query: 1038 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 859
NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH
Sbjct: 482 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 541
Query: 858 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 679
HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ
Sbjct: 542 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 601
Query: 678 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 499
NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW
Sbjct: 602 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 661
Query: 498 FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF 319
FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF
Sbjct: 662 FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF 721
Query: 318 VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY 139
VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY
Sbjct: 722 VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY 781
Query: 138 PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 4
PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA
Sbjct: 782 PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 826
Score = 40.8 bits (94), Expect(2) = 0.0
Identities = 21/31 (67%), Positives = 22/31 (70%)
Frame = -2
Query: 2387 SNNSXXXXXXXXXKLVENYTCPFARTEGTAN 2295
SNNS KLVENYTCPFARTEGTA+
Sbjct: 7 SNNSKPPKPRKKPKLVENYTCPFARTEGTAS 37
>gi|25152478|ref|NP_501491.2| heparan SulphoTransferase, N-deacetylase
N-sulfotransferase (99.1 kD) (hst-1) [Caenorhabditis
elegans]
gi|15076492|dbj|BAB62394.1| N-deacetylase/N-sulfotransferase
[Caenorhabditis elegans]
Length = 852
Score = 1576 bits (4082), Expect(2) = 0.0
Identities = 764/765 (99%), Positives = 765/765 (99%)
Frame = -1
Query: 2298 QHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
+HGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD
Sbjct: 88 RHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 147
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 1939
KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR
Sbjct: 148 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 207
Query: 1938 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 1759
QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV
Sbjct: 208 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 267
Query: 1758 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 1579
KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ
Sbjct: 268 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 327
Query: 1578 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 1399
NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ
Sbjct: 328 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 387
Query: 1398 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 1219
NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK
Sbjct: 388 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 447
Query: 1218 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 1039
GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ
Sbjct: 448 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 507
Query: 1038 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 859
NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH
Sbjct: 508 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 567
Query: 858 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 679
HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ
Sbjct: 568 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 627
Query: 678 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 499
NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW
Sbjct: 628 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 687
Query: 498 FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF 319
FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF
Sbjct: 688 FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF 747
Query: 318 VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY 139
VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY
Sbjct: 748 VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY 807
Query: 138 PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 4
PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA
Sbjct: 808 PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 852
Score = 40.8 bits (94), Expect(2) = 0.0
Identities = 21/31 (67%), Positives = 22/31 (70%)
Frame = -2
Query: 2387 SNNSXXXXXXXXXKLVENYTCPFARTEGTAN 2295
SNNS KLVENYTCPFARTEGTA+
Sbjct: 33 SNNSKPPKPRKKPKLVENYTCPFARTEGTAS 63
>gi|14587790|dbj|BAB61757.1| N-deacetylase/N-sulfotransferase
[Caenorhabditis elegans]
Length = 814
Score = 1576 bits (4082), Expect(2) = 0.0
Identities = 764/765 (99%), Positives = 765/765 (99%)
Frame = -1
Query: 2298 QHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
+HGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD
Sbjct: 50 RHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 109
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 1939
KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR
Sbjct: 110 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 169
Query: 1938 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 1759
QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV
Sbjct: 170 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 229
Query: 1758 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 1579
KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ
Sbjct: 230 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 289
Query: 1578 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 1399
NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ
Sbjct: 290 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 349
Query: 1398 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 1219
NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK
Sbjct: 350 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 409
Query: 1218 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 1039
GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ
Sbjct: 410 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 469
Query: 1038 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 859
NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH
Sbjct: 470 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 529
Query: 858 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 679
HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ
Sbjct: 530 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 589
Query: 678 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 499
NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW
Sbjct: 590 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 649
Query: 498 FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF 319
FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF
Sbjct: 650 FQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIF 709
Query: 318 VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY 139
VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY
Sbjct: 710 VDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKY 769
Query: 138 PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 4
PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA
Sbjct: 770 PEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 814
Score = 38.5 bits (88), Expect(2) = 0.0
Identities = 16/17 (94%), Positives = 17/17 (99%)
Frame = -2
Query: 2345 LVENYTCPFARTEGTAN 2295
LVENYTCPFARTEGTA+
Sbjct: 9 LVENYTCPFARTEGTAS 25
>gi|27374524|gb|AAB37730.3| Heparan sulphotransferase protein 1
[Caenorhabditis elegans]
Length = 715
Score = 1482 bits (3836), Expect = 0.0
Identities = 715/715 (100%), Positives = 715/715 (100%)
Frame = -1
Query: 2148 MAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSII 1969
MAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSII
Sbjct: 1 MAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSII 60
Query: 1968 HRISKIGNYRQFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERII 1789
HRISKIGNYRQFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERII
Sbjct: 61 HRISKIGNYRQFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERII 120
Query: 1788 FGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLIS 1609
FGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLIS
Sbjct: 121 FGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLIS 180
Query: 1608 TQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHN 1429
TQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHN
Sbjct: 181 TQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHN 240
Query: 1428 FTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEY 1249
FTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEY
Sbjct: 241 FTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEY 300
Query: 1248 PHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLN 1069
PHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLN
Sbjct: 301 PHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLN 360
Query: 1068 PISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPL 889
PISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPL
Sbjct: 361 PISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPL 420
Query: 888 WTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGS 709
WTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGS
Sbjct: 421 WTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGS 480
Query: 708 FEEVQFFGGQNYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIIL 529
FEEVQFFGGQNYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIIL
Sbjct: 481 FEEVQFFGGQNYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIIL 540
Query: 528 QNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWL 349
QNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWL
Sbjct: 541 QNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWL 600
Query: 348 EHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTK 169
EHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTK
Sbjct: 601 EHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTK 660
Query: 168 CLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 4
CLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA
Sbjct: 661 CLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 715
>gi|14587792|dbj|BAB61758.1| N-deacetylase/N-sulfotransferase
[Caenorhabditis elegans]
Length = 696
Score = 1440 bits (3727), Expect = 0.0
Identities = 696/696 (100%), Positives = 696/696 (100%)
Frame = -1
Query: 2091 MFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYRQFSSSDPAD 1912
MFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYRQFSSSDPAD
Sbjct: 1 MFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYRQFSSSDPAD 60
Query: 1911 WILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLDALW 1732
WILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLDALW
Sbjct: 61 WILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLDALW 120
Query: 1731 WAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFS 1552
WAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFS
Sbjct: 121 WAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFS 180
Query: 1551 GSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQNMH 1372
GSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQNMH
Sbjct: 181 GSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQNMH 240
Query: 1371 LPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHV 1192
LPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHV
Sbjct: 241 LPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHV 300
Query: 1191 LPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLAL 1012
LPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLAL
Sbjct: 301 LPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLAL 360
Query: 1011 YTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSIN 832
YTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSIN
Sbjct: 361 YTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSIN 420
Query: 831 CTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWY 652
CTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWY
Sbjct: 421 CTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWY 480
Query: 651 MSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHED 472
MSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHED
Sbjct: 481 MSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHED 540
Query: 471 PVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMK 292
PVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMK
Sbjct: 541 PVAITAGSLEVILDSNSTSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMK 600
Query: 291 PPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKYPEMPENLRR 112
PPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKYPEMPENLRR
Sbjct: 601 PPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGRKYPEMPENLRR 660
Query: 111 KLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 4
KLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA
Sbjct: 661 KLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIRA 696
>gi|39580996|emb|CAE72477.1| Hypothetical protein CBG19653
[Caenorhabditis briggsae]
Length = 854
Score = 1327 bits (3434), Expect(2) = 0.0
Identities = 613/766 (80%), Positives = 705/766 (92%), Gaps = 2/766 (0%)
Frame = -1
Query: 2298 QHGKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
+HGK+IIQILNSQK FKAEA+SKNLPVLT+++RG+YSLII+ENYYKYLNMA+WNRQLLD
Sbjct: 90 RHGKSIIQILNSQKFAFKAEAISKNLPVLTSAKRGKYSLIIVENYYKYLNMARWNRQLLD 149
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKIGNYR 1939
KYCKEYRVP+FSF++SKPNDQLKRI+IKGSSLWMWQNQRI RL V+PS IH+ISKIG YR
Sbjct: 150 KYCKEYRVPLFSFIASKPNDQLKRIRIKGSSLWMWQNQRINRLTVSPSPIHKISKIGAYR 209
Query: 1938 QFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVERIIFGRNLTDFQV 1759
++ + +DWILFE SE FES+L+GTVK+GYERAVV+RD G EDGVE++IFGRNLTDFQ+
Sbjct: 210 NLTTQE-SDWILFEISENFESILTGTVKNGYERAVVLRDLGREDGVEKVIFGRNLTDFQI 268
Query: 1758 KITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLISTQKEFRNYVQ 1579
KITFLDALWWAMG++K F LDRFVQVDIDDVFVGAQ TRIVEEDVR LIS Q FRN+++
Sbjct: 269 KITFLDALWWAMGDEKLFGLDRFVQVDIDDVFVGAQSTRIVEEDVRHLISAQNHFRNFIE 328
Query: 1578 NFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEHNFTYLEAIMAQ 1399
NF F+LGFSGSYFRNGDD EDRGDE L+ENAEKFVWFPHMWRHNHAHEHNFTYLE+IM Q
Sbjct: 329 NFKFLLGFSGSYFRNGDDFEDRGDEILIENAEKFVWFPHMWRHNHAHEHNFTYLESIMVQ 388
Query: 1398 NKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEYPHFKPATARK 1219
N+LFAQNMHLP+DYPYAIAPQHDGVFPVHEQ++ AW+K+WNV+VTATEEYPH KPAT RK
Sbjct: 389 NRLFAQNMHLPIDYPYAIAPQHDGVFPVHEQMYEAWKKIWNVTVTATEEYPHLKPATGRK 448
Query: 1218 GFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLNPISIFMTHQQ 1039
GFIH+GIHVLPRQTCGLYTHTQ FDEYPEGF KV KSI+GGDLFFTILLNPISIFMTHQQ
Sbjct: 449 GFIHSGIHVLPRQTCGLYTHTQFFDEYPEGFQKVIKSIQGGDLFFTILLNPISIFMTHQQ 508
Query: 1038 NYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPLWTNPCTDPRH 859
NYA+DRLALYTFENLFRF+ CWTNI+LKWQ P+ S+++YF+KFP+ER PLWTNPC+DPRH
Sbjct: 509 NYAHDRLALYTFENLFRFLNCWTNIRLKWQSPVESAKMYFEKFPEERIPLWTNPCSDPRH 568
Query: 858 HAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGSFEEVQFFGGQ 679
AILPPS++C+KKSLPDLLIIGPQKTGSTALASFL+LHPN SQN +PGSFEE+QFF GQ
Sbjct: 569 QAILPPSMSCSKKSLPDLLIIGPQKTGSTALASFLALHPNVSQNMEIPGSFEEIQFFSGQ 628
Query: 678 NYLKGVEWYMSNFPSSSTVTFEKSATYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSW 499
NYLKGVEWYMS FP+ +TV FEKSATYFDNPSA +QAA++VPHAK+VIILQNP QRAYSW
Sbjct: 629 NYLKGVEWYMSKFPNETTVIFEKSATYFDNPSAARQAAAMVPHAKLVIILQNPTQRAYSW 688
Query: 498 FQHILAHEDPVAITAGSLEVILDSNSTSSK--KVRQRCISGGRYVHHLTKWLEHFSLQQM 325
FQH++AH+DP+A+++ SL+VIL+S S+ S K+RQRC+SGGRYVHHL KWLEHFSLQQ+
Sbjct: 689 FQHLIAHKDPIAMSSESLDVILNSTSSESAKFKIRQRCLSGGRYVHHLDKWLEHFSLQQI 748
Query: 324 IFVDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCRLLDGKTKCLGESKGR 145
F+DSDEL+ +P VL+SLSKWLDLPEFPFET+IR+SPSKGFHCRL++GKT+CLGESKGR
Sbjct: 749 QFIDSDELRKEPAKVLSSLSKWLDLPEFPFETHIRFSPSKGFHCRLINGKTECLGESKGR 808
Query: 144 KYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEESVRIR 7
KY EM + LR+KLD IF+LDNSAL+KFLRKNRLKIP WLEE+VRIR
Sbjct: 809 KYSEMSQELRQKLDGIFALDNSALFKFLRKNRLKIPDWLEEAVRIR 854
Score = 25.0 bits (53), Expect(2) = 0.0
Identities = 9/20 (45%), Positives = 14/20 (70%)
Frame = -2
Query: 2342 VENYTCPFARTEGTANMEKR 2283
VENYTCPF + + + +K+
Sbjct: 48 VENYTCPFEKADFSNFKDKK 67
>gi|31217059|ref|XP_316354.1| ENSANGP00000013790 [Anopheles gambiae]
gi|21298756|gb|EAA10901.1| ENSANGP00000013790 [Anopheles gambiae str.
PEST]
Length = 835
Score = 684 bits (1765), Expect = 0.0
Identities = 345/782 (44%), Positives = 492/782 (62%), Gaps = 21/782 (2%)
Frame = -1
Query: 2292 GKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLDKY 2113
GK+I ++L ++++K E K+LPVLT +GRY +I+ EN KYLNM WNRQLLDKY
Sbjct: 56 GKSITELLVHNRIKYKVEVAGKSLPVLTNQDKGRYGVIVFENLDKYLNMDNWNRQLLDKY 115
Query: 2112 CKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISKIGNYRQ 1936
C++Y V + F+S + L +++G L++ N R++ ++ P S + R+++ G+
Sbjct: 116 CRDYSVGIIGFVSPS-EETLVGAQLRGFPLYVHTNLRLRDASLNPGSPVLRLTRAGD-TA 173
Query: 1935 FSSSDPADWILFETSEKFESVLSGTVKSGYER----------AVVVRDKGLEDGVERIIF 1786
+ DW +F+ + L K+ + A V++D G DG++RI+F
Sbjct: 174 WGPLPGNDWAIFQHNHSGYEPLEWAQKNVMDYPTDGVAQPPLATVLQDHGQLDGIQRILF 233
Query: 1785 GRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLIST 1606
G L + ++ FLD+L + Q S L+R + +DIDD+FVG +GTR+ +DV LI+T
Sbjct: 234 GSGLKFWLHRLLFLDSLSYLSHGQLSLNLERRILIDIDDIFVGEKGTRLKPDDVHALIAT 293
Query: 1605 QKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEH-N 1429
Q V F F LGFSG YF +G E+ GD+ L+ N +F WF HMW H H + N
Sbjct: 294 QNRIGEMVPGFRFNLGFSGKYFHHGTHEENLGDDMLLRNVAQFNWFSHMWNHQQPHLYEN 353
Query: 1428 FTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEY 1249
T L M NK FA+ +P D Y+++P H GV+P HE L+ AW+KVWN+ VT+TEEY
Sbjct: 354 VTQLMNDMMLNKDFAKEHGIPTDSGYSVSPHHSGVYPAHELLYTAWKKVWNIKVTSTEEY 413
Query: 1248 PHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLN 1069
PH +PA R+GFIH I VLPRQTCGL+THT D YP G DK+ +SI GG+LF TI+ N
Sbjct: 414 PHLRPARLRRGFIHRNIMVLPRQTCGLFTHTICIDSYPGGRDKLDESIRGGELFQTIVYN 473
Query: 1068 PISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPL 889
PI+IFMTH NY DRLALYTFE++ +F++CWTN+KL PL +LYF+ P+ER P+
Sbjct: 474 PINIFMTHMSNYGNDRLALYTFESVIKFLRCWTNLKLTSVPPLQLGELYFKLHPEERDPI 533
Query: 888 WTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGS 709
W NP DPRH I + N + +LP LL +GPQKTGSTA +FLS+HP + N P +
Sbjct: 534 WGNPADDPRHAKIW--AGNKRRTTLPKLLGLGPQKTGSTAFYTFLSMHPAVASNLPNSDT 591
Query: 708 FEEVQFFGGQNYLKGVEWYMSNFPSSSTVT-----FEKSATYFDNPSAPKQAASLVPHAK 544
FEE+QFF G NY +G++WY++ FP T FEKSATYFD PK+A +L+P A+
Sbjct: 592 FEEIQFFNGNNYYRGLDWYLNFFPLQPNDTDDKFMFEKSATYFDGELVPKRAHALLPKAQ 651
Query: 543 IVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNS--TSSKKVRQRCISGGRYV 370
+V IL +PA+RAYSW+QHI AH DP+A +VI S + + + +R RC++ G+Y
Sbjct: 652 LVTILISPAKRAYSWYQHIKAHGDPIANNYSFYQVITASEAEPKALRDLRNRCLNPGKYA 711
Query: 369 HHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCR 190
HL +WL + QQ+ +D ++LK P TV+N L ++L LP F + ++R+ KGF+C+
Sbjct: 712 QHLERWLACYPPQQLYIIDGEQLKTNPVTVMNDLQRFLKLPPFDYSRHLRFDNKKGFYCQ 771
Query: 189 LL-DGKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK-NRLKIPTWLEESV 16
++ D + KCLG+SKGR+YP M + + L K + + N AL K L+K IP WL+E +
Sbjct: 772 VVSDNRNKCLGKSKGRQYPPMDDRSAKMLQKYYRIHNQALVKLLKKLGSRPIPQWLKEDL 831
Query: 15 RI 10
+
Sbjct: 832 SV 833
>gi|13242253|ref|NP_077337.1| N-deacetylase/N-sulfotransferase
(heparan glucosaminyl) 1; heparan
sulfate-N-deacetylase/N-sulfotransferase [Rattus
norvegicus]
gi|401136|sp|Q02353|HSS1_RAT Heparan sulfate
N-deacetylase/N-sulfotransferase (N-HSST) (HSNST)
([Heparan sulfate]-glucosamine N-sulfotransferase)
(N-heparan sulfate sulfotransferase) (Glucosaminyl
N-deacetylase/N-sulfotransferase)
gi|205703|gb|AAA41701.1| N-heparan sulfate sulfotransferase
Length = 882
Score = 683 bits (1763), Expect = 0.0
Identities = 355/794 (44%), Positives = 489/794 (60%), Gaps = 30/794 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ ++ IL S + +++ E ++P LT RGR++LII EN KY+N+ WNR
Sbjct: 93 YSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS----IIHR 1963
+LLDKYC Y V + F + N L ++KG L++ N ++ ++ P + R
Sbjct: 153 ELLDKYCVAYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCSINPKSPLLYVTR 211
Query: 1962 ISKIGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE--------------RAVVV 1828
S++ + DW +F+++ +E VL +S A VV
Sbjct: 212 PSEV----EKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVV 267
Query: 1827 RDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQG 1648
+D GL DG++R++FG NL + K+ F+DA+ + G + S LDR++ VDIDD+FVG +G
Sbjct: 268 QDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEG 327
Query: 1647 TRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWF 1468
TR+ EDV+ L TQ E R ++ NFTF LG+SG +F G D ED GD+ L+ ++F WF
Sbjct: 328 TRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWF 387
Query: 1467 PHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAW 1291
PHMW H H HN + L MA NK FA +P D YA+AP H GV+PVH QL+ AW
Sbjct: 388 PHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAW 447
Query: 1290 RKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQK 1111
++VWN+ VT+TEEYPH KPA R+GFIH GI VLPRQTCGL+THT ++EYP G ++ K
Sbjct: 448 KQVWNIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDK 507
Query: 1110 SIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSS 931
I GG+LF T+LLNPIS+FMTH NY DRL LYTF++L RF+ WTN++L+ P+ +
Sbjct: 508 IINGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLA 567
Query: 930 QLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLS 751
Q YFQ F +E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL
Sbjct: 568 QKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLG 625
Query: 750 LHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPS 583
+HP+ S N P +FEE+QFF G NY KG++WYM FP S T FEKSA YFD+
Sbjct: 626 MHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEV 685
Query: 582 APKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSK-- 409
AP++AA+L+P AK++ IL NPA RAYSW+QH AH+DPVA+ EVI SSK
Sbjct: 686 APRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLR 745
Query: 408 KVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFE 232
++ RC+ G Y H+ +WL F Q++ +D L+ +P V++++ K+L + +
Sbjct: 746 ALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYH 805
Query: 231 TYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK 55
+ + P KGF C+LL+ GKTKCLG+SKGRKYPEM + R L + N L K L K
Sbjct: 806 KTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYK 865
Query: 54 NRLKIPTWLEESVR 13
+PTWL E ++
Sbjct: 866 MGQTLPTWLREDLQ 879
>gi|348494|pir||A42855 N-heparan sulfate sulfotransferase - rat
Length = 882
Score = 683 bits (1763), Expect = 0.0
Identities = 355/794 (44%), Positives = 489/794 (60%), Gaps = 30/794 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ ++ IL S + +++ E ++P LT RGR++LII EN KY+N+ WNR
Sbjct: 93 YSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS----IIHR 1963
+LLDKYC Y V + F + N L ++KG L++ N ++ ++ P + R
Sbjct: 153 ELLDKYCVAYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCSINPKSPLLYVTR 211
Query: 1962 ISKIGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE--------------RAVVV 1828
S++ + DW +F+++ +E VL +S A VV
Sbjct: 212 PSEV----EKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVV 267
Query: 1827 RDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQG 1648
+D GL DG++R++FG NL + K+ F+DA+ + G + S LDR++ VDIDD+FVG +G
Sbjct: 268 QDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEG 327
Query: 1647 TRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWF 1468
TR+ EDV+ L TQ E R ++ NFTF LG+SG +F G D ED GD+ L+ ++F WF
Sbjct: 328 TRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWF 387
Query: 1467 PHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAW 1291
PHMW H H HN + L MA NK FA +P D YA+AP H GV+PVH QL+ AW
Sbjct: 388 PHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAW 447
Query: 1290 RKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQK 1111
++VWN+ VT+TEEYPH KPA R+GFIH GI VLPRQTCGL+THT ++EYP G ++ K
Sbjct: 448 KQVWNIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDK 507
Query: 1110 SIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSS 931
I GG+LF T+LLNPIS+FMTH NY DRL LYTF++L RF+ WTN++L+ P+ +
Sbjct: 508 IINGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLA 567
Query: 930 QLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLS 751
Q YFQ F +E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL
Sbjct: 568 QKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLG 625
Query: 750 LHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPS 583
+HP+ S N P +FEE+QFF G NY KG++WYM FP S T FEKSA YFD+
Sbjct: 626 MHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEV 685
Query: 582 APKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSK-- 409
AP++AA+L+P AK++ IL NPA RAYSW+QH AH+DPVA+ EVI SSK
Sbjct: 686 APRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLR 745
Query: 408 KVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFE 232
++ RC+ G Y H+ +WL F Q++ +D L+ +P V++++ K+L + +
Sbjct: 746 ALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYH 805
Query: 231 TYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK 55
+ + P KGF C+LL+ GKTKCLG+SKGRKYPEM + R L + N L K L K
Sbjct: 806 KTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYK 865
Query: 54 NRLKIPTWLEESVR 13
+PTWL E ++
Sbjct: 866 MGQTLPTWLREDLQ 879
>gi|31217052|ref|XP_316352.1| ENSANGP00000004205 [Anopheles gambiae]
gi|21299302|gb|EAA11447.1| ENSANGP00000004205 [Anopheles gambiae str.
PEST]
Length = 860
Score = 683 bits (1763), Expect = 0.0
Identities = 345/780 (44%), Positives = 491/780 (62%), Gaps = 21/780 (2%)
Frame = -1
Query: 2292 GKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLDKY 2113
GK+I ++L ++++K E K+LPVLT +GRY +I+ EN KYLNM WNRQLLDKY
Sbjct: 84 GKSITELLVHNRIKYKVEVAGKSLPVLTNQDKGRYGVIVFENLDKYLNMDNWNRQLLDKY 143
Query: 2112 CKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISKIGNYRQ 1936
C++Y V + F+S + L +++G L++ N R++ ++ P S + R+++ G+
Sbjct: 144 CRDYSVGIIGFVSPS-EETLVGAQLRGFPLYVHTNLRLRDASLNPGSPVLRLTRAGD-TA 201
Query: 1935 FSSSDPADWILFETSEKFESVLSGTVKSGYER----------AVVVRDKGLEDGVERIIF 1786
+ DW +F+ + L K+ + A V++D G DG++RI+F
Sbjct: 202 WGPLPGNDWAIFQHNHSGYEPLEWAQKNVMDYPTDGVAQPPLATVLQDHGQLDGIQRILF 261
Query: 1785 GRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKLIST 1606
G L + ++ FLD+L + Q S L+R + +DIDD+FVG +GTR+ +DV LI+T
Sbjct: 262 GSGLKFWLHRLLFLDSLSYLSHGQLSLNLERRILIDIDDIFVGEKGTRLKPDDVHALIAT 321
Query: 1605 QKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHEH-N 1429
Q V F F LGFSG YF +G E+ GD+ L+ N +F WF HMW H H + N
Sbjct: 322 QNRIGEMVPGFRFNLGFSGKYFHHGTHEENLGDDMLLRNVAQFNWFSHMWNHQQPHLYEN 381
Query: 1428 FTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTATEEY 1249
T L M NK FA+ +P D Y+++P H GV+P HE L+ AW+KVWN+ VT+TEEY
Sbjct: 382 VTQLMNDMMLNKDFAKEHGIPTDSGYSVSPHHSGVYPAHELLYTAWKKVWNIKVTSTEEY 441
Query: 1248 PHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTILLN 1069
PH +PA R+GFIH I VLPRQTCGL+THT D YP G DK+ +SI GG+LF TI+ N
Sbjct: 442 PHLRPARLRRGFIHRNIMVLPRQTCGLFTHTICIDSYPGGRDKLDESIRGGELFQTIVYN 501
Query: 1068 PISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDERTPL 889
PI+IFMTH NY DRLALYTFE++ +F++CWTN+KL PL +LYF+ P+ER P+
Sbjct: 502 PINIFMTHMSNYGNDRLALYTFESVIKFLRCWTNLKLTSVPPLQLGELYFKLHPEERDPI 561
Query: 888 WTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPVPGS 709
W NP DPRH I + N + +LP LL +GPQKTGSTA +FLS+HP + N P +
Sbjct: 562 WGNPADDPRHAKIW--AGNKRRTTLPKLLGLGPQKTGSTAFYTFLSMHPAVASNLPNSDT 619
Query: 708 FEEVQFFGGQNYLKGVEWYMSNFPSSSTVT-----FEKSATYFDNPSAPKQAASLVPHAK 544
FEE+QFF G NY +G++WY++ FP T FEKSATYFD PK+A +L+P A+
Sbjct: 620 FEEIQFFNGNNYYRGLDWYLNFFPLQPNDTDDKFMFEKSATYFDGELVPKRAHALLPKAQ 679
Query: 543 IVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNS--TSSKKVRQRCISGGRYV 370
+V IL +PA+RAYSW+QHI AH DP+A +VI S + + + +R RC++ G+Y
Sbjct: 680 LVTILISPAKRAYSWYQHIKAHGDPIANNYSFYQVITASEAEPKALRDLRNRCLNPGKYA 739
Query: 369 HHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPEFPFETYIRYSPSKGFHCR 190
HL +WL + QQ+ +D ++LK P TV+N L ++L LP F + ++R+ KGF+C+
Sbjct: 740 QHLERWLACYPPQQLYIIDGEQLKTNPVTVMNDLQRFLKLPPFDYSRHLRFDNKKGFYCQ 799
Query: 189 LL-DGKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK-NRLKIPTWLEESV 16
++ D + KCLG+SKGR+YP M + + L K + + N AL K L+K IP WL+E +
Sbjct: 800 VVSDNRNKCLGKSKGRQYPPMDDRSAKMLQKYYRIHNQALVKLLKKLGSRPIPQWLKEDL 859
>gi|42734444|ref|NP_032332.2| N-deacetylase/N-sulfotransferase
(heparan glucosaminyl) 1; heparan
sulfate-N-deacetylase/N-sulfotransferase;
N-deacetylase/N-sulfotransferase-1; glucosaminyl
N-deacetylase/N-sulfotransferase 1 [Mus musculus]
gi|4322251|gb|AAD15980.1| heparan sulfate
N-deacetylase/N-sulfotransferase 1 [Mus musculus]
gi|41946076|gb|AAH66098.1| N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 1 [Mus musculus]
Length = 882
Score = 682 bits (1761), Expect = 0.0
Identities = 357/794 (44%), Positives = 488/794 (60%), Gaps = 30/794 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ ++ IL S + +++ E ++P LT RGR++LII EN KY+N+ WNR
Sbjct: 93 YSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS----IIHR 1963
+LLDKYC Y V + F + N L ++KG L++ N ++ ++ P + R
Sbjct: 153 ELLDKYCVAYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCSINPKSPLLYVTR 211
Query: 1962 ISKIGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE--------------RAVVV 1828
S++ + DW +F+++ +E VL +S A VV
Sbjct: 212 PSEV----EKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVV 267
Query: 1827 RDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQG 1648
+D GL DG++R++FG NL + K+ F+DA+ + G + S LDR++ VDIDD+FVG +G
Sbjct: 268 QDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEG 327
Query: 1647 TRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWF 1468
TR+ EDV+ L TQ E R ++ NFTF LG+SG +F G D ED GD+ L+ ++F WF
Sbjct: 328 TRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWF 387
Query: 1467 PHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAW 1291
PHMW H H HN + L MA NK FA +P D YA+AP H GV+PVH QL+ AW
Sbjct: 388 PHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAW 447
Query: 1290 RKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQK 1111
++VW + VT+TEEYPH KPA R+GFIH GI VLPRQTCGL+THT ++EYP G ++ K
Sbjct: 448 KQVWGIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDK 507
Query: 1110 SIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSS 931
I GG+LF T+LLNPISIFMTH NY DRL LYTF++L RF+ WTN++L+ P+ +
Sbjct: 508 IINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLA 567
Query: 930 QLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLS 751
Q YFQ F +E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL
Sbjct: 568 QKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLG 625
Query: 750 LHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPS 583
+HP+ S N P +FEE+QFF G NY KG++WYM FP S T FEKSA YFD+
Sbjct: 626 MHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEV 685
Query: 582 APKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSK-- 409
AP++AA+L+P AKI+ IL NPA RAYSW+QH AH+DPVA+ EVI SSK
Sbjct: 686 APRRAAALLPKAKILSILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLR 745
Query: 408 KVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFE 232
++ RC+ G Y H+ +WL F Q++ +D L+ +P V++++ K+L + +
Sbjct: 746 ALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYH 805
Query: 231 TYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK 55
+ + P KGF C+LL+ GKTKCLG+SKGRKYPEM + R L F N L K L K
Sbjct: 806 KTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYFRDHNIELSKLLYK 865
Query: 54 NRLKIPTWLEESVR 13
+PTWL E ++
Sbjct: 866 MGQTLPTWLREDLQ 879
>gi|3136148|gb|AAC17228.1| heparan sulfate glucosaminyl
N-deacetylase/N-sulfotransferase; DAST-1 [Mus musculus]
Length = 882
Score = 682 bits (1760), Expect = 0.0
Identities = 357/794 (44%), Positives = 488/794 (60%), Gaps = 30/794 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ ++ IL S + +++ E ++P LT RGR++LII EN KY+N+ WNR
Sbjct: 93 YSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS----IIHR 1963
+LLDKYC Y V + F + N L ++KG L++ N ++ ++ P + R
Sbjct: 153 ELLDKYCVAYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCSINPKSPLLYVTR 211
Query: 1962 ISKIGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE--------------RAVVV 1828
S++ + DW +F+++ +E VL +S A VV
Sbjct: 212 PSEV----EKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVV 267
Query: 1827 RDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQG 1648
+D GL DG++R++FG NL + K+ F+DA+ + G + S LDR++ VDIDD+FVG +G
Sbjct: 268 QDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEG 327
Query: 1647 TRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWF 1468
TR+ EDV+ L TQ E R ++ NFTF LG+SG +F G D ED GD+ L+ ++F WF
Sbjct: 328 TRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWF 387
Query: 1467 PHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAW 1291
PHMW H H HN + L MA NK FA +P D YA+AP H GV+PVH QL+ AW
Sbjct: 388 PHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAW 447
Query: 1290 RKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQK 1111
++VW + VT+TEEYPH KPA R+GFIH GI VLPRQTCGL+THT ++EYP G ++ K
Sbjct: 448 KQVWGIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDK 507
Query: 1110 SIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSS 931
I GG+LF T+LLNPISIFMTH NY DRL LYTF++L RF+ WTN++L+ P+ +
Sbjct: 508 IINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLA 567
Query: 930 QLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLS 751
Q YFQ F +E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL
Sbjct: 568 QKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLG 625
Query: 750 LHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPS 583
+HP+ S N P +FEE+QFF G NY KG++WYM FP S T FEKSA YFD+
Sbjct: 626 MHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEV 685
Query: 582 APKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSK-- 409
AP++AA+L+P AKI+ IL NPA RAYSW+QH AH+DPVA+ EVI SSK
Sbjct: 686 APRRAAALLPKAKILSILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLR 745
Query: 408 KVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFE 232
++ RC+ G Y H+ +WL F Q++ +D L+ +P V++++ K+L + +
Sbjct: 746 ALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVVDTVQKFLGVTSTVDYH 805
Query: 231 TYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK 55
+ + P KGF C+LL+ GKTKCLG+SKGRKYPEM + R L F N L K L K
Sbjct: 806 KTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYFRDHNIELSKLLYK 865
Query: 54 NRLKIPTWLEESVR 13
+PTWL E ++
Sbjct: 866 MGQTLPTWLREDLQ 879
>gi|5668903|gb|AAD46061.1| heparan N-deacetylase/N-sulfotransferase 3
[Homo sapiens]
Length = 876
Score = 681 bits (1756), Expect = 0.0
Identities = 349/783 (44%), Positives = 482/783 (60%), Gaps = 23/783 (2%)
Frame = -1
Query: 2292 GKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
G+ II IL S + Q+ E +LPVL +G+Y LII EN KY+NM WNR LLD
Sbjct: 95 GQDIIMILESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLD 154
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISKIGNY 1942
KYC EY V + F + ++ ++KG ++ N ++ + P S + R++K
Sbjct: 155 KYCVEYGVGVIGFHKTSEKS-VQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKL 213
Query: 1941 RQFSSSDPADWILFETSE-----------KFESVLSGTVKSGYERAVVVRDKGLEDGVER 1795
+ S DW +F+ + K LS ++ G A ++ D GL DG++R
Sbjct: 214 EK-GSLPGTDWTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQR 272
Query: 1794 IIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKL 1615
++FG NL + K+ F+DA+ + G + + +LDR++ VDIDD+FVG +GTR+ DV+ L
Sbjct: 273 VLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKAL 332
Query: 1614 ISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHE 1435
+ TQ R + NFTF LGFSG ++ G + ED GD+ L+ + ++F WFPHMW H H
Sbjct: 333 LDTQNLLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHL 392
Query: 1434 -HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTAT 1258
HN + L M NK FA +P D YA+AP H GV+PVH QL+ AW+KVWN+ +T+T
Sbjct: 393 FHNESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITST 452
Query: 1257 EEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTI 1078
EEYPH KPA R+GFIH I VLPRQTCGL+THT + EYP G ++ KSI+GG+LFFT+
Sbjct: 453 EEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTV 512
Query: 1077 LLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDER 898
+LNPISIFMTH NY DRL LYTF NL F+K WTN++L+ P+ + YF+ FPD++
Sbjct: 513 VLNPISIFMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQK 572
Query: 897 TPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPV 718
PLW NPC D RH I C + LP L+IGPQKTG+TAL FL +HP+ N+P
Sbjct: 573 DPLWQNPCDDKRHRDIWSKEKTCDR--LPKFLVIGPQKTGTTALYLFLVMHPSILSNSPS 630
Query: 717 PGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPSAPKQAASLVPH 550
P +FEEVQFF NY +G++WYM FP S VT FEKSA YF + APK+AASLVP
Sbjct: 631 PKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPK 690
Query: 549 AKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSS--KKVRQRCISGGR 376
AKI+ IL +P+ RAYSW+QH +HEDP A+ EVI S + +++RC+ G
Sbjct: 691 AKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGW 750
Query: 375 YVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLD-LPEFPFETYIRYSPSKGF 199
Y H+ +WL +F Q++ +D +L+ P TV++ + K+L LP + + + + KGF
Sbjct: 751 YASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGF 810
Query: 198 HCRLL-DGKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEE 22
C+LL +GKTKCLG+SKGRKYP M + R L + N L K L K +P+WL +
Sbjct: 811 WCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQ 870
Query: 21 SVR 13
++
Sbjct: 871 ELQ 873
>gi|4758766|ref|NP_004775.1| N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 3 [Homo sapiens]
gi|4322247|gb|AAD15978.1| heparan sulfate
N-deacetylase/N-sulfotransferase 3 [Homo sapiens]
Length = 873
Score = 681 bits (1756), Expect = 0.0
Identities = 349/783 (44%), Positives = 482/783 (60%), Gaps = 23/783 (2%)
Frame = -1
Query: 2292 GKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
G+ II IL S + Q+ E +LPVL +G+Y LII EN KY+NM WNR LLD
Sbjct: 92 GQDIIMILESSRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINMDSWNRSLLD 151
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISKIGNY 1942
KYC EY V + F + ++ ++KG ++ N ++ + P S + R++K
Sbjct: 152 KYCVEYGVGVIGFHKTSEKS-VQSFQLKGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKL 210
Query: 1941 RQFSSSDPADWILFETSE-----------KFESVLSGTVKSGYERAVVVRDKGLEDGVER 1795
+ S DW +F+ + K LS ++ G A ++ D GL DG++R
Sbjct: 211 EK-GSLPGTDWTVFQINHSAYQPVIFAKVKTPENLSPSISKGAFYATIIHDLGLHDGIQR 269
Query: 1794 IIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKL 1615
++FG NL + K+ F+DA+ + G + + +LDR++ VDIDD+FVG +GTR+ DV+ L
Sbjct: 270 VLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKAL 329
Query: 1614 ISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHE 1435
+ TQ R + NFTF LGFSG ++ G + ED GD+ L+ + ++F WFPHMW H H
Sbjct: 330 LDTQNLLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHL 389
Query: 1434 -HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTAT 1258
HN + L M NK FA +P D YA+AP H GV+PVH QL+ AW+KVWN+ +T+T
Sbjct: 390 FHNESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITST 449
Query: 1257 EEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTI 1078
EEYPH KPA R+GFIH I VLPRQTCGL+THT + EYP G ++ KSI+GG+LFFT+
Sbjct: 450 EEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTV 509
Query: 1077 LLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDER 898
+LNPISIFMTH NY DRL LYTF NL F+K WTN++L+ P+ + YF+ FPD++
Sbjct: 510 VLNPISIFMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQK 569
Query: 897 TPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPV 718
PLW NPC D RH I C + LP L+IGPQKTG+TAL FL +HP+ N+P
Sbjct: 570 DPLWQNPCDDKRHRDIWSKEKTCDR--LPKFLVIGPQKTGTTALYLFLVMHPSILSNSPS 627
Query: 717 PGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPSAPKQAASLVPH 550
P +FEEVQFF NY +G++WYM FP S VT FEKSA YF + APK+AASLVP
Sbjct: 628 PKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPK 687
Query: 549 AKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSS--KKVRQRCISGGR 376
AKI+ IL +P+ RAYSW+QH +HEDP A+ EVI S + +++RC+ G
Sbjct: 688 AKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGW 747
Query: 375 YVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLD-LPEFPFETYIRYSPSKGF 199
Y H+ +WL +F Q++ +D +L+ P TV++ + K+L LP + + + + KGF
Sbjct: 748 YASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGF 807
Query: 198 HCRLL-DGKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEE 22
C+LL +GKTKCLG+SKGRKYP M + R L + N L K L K +P+WL +
Sbjct: 808 WCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQ 867
Query: 21 SVR 13
++
Sbjct: 868 ELQ 870
>gi|49118699|gb|AAH72733.1| Unknown (protein for MGC:79080) [Xenopus
laevis]
Length = 878
Score = 679 bits (1753), Expect = 0.0
Identities = 349/786 (44%), Positives = 481/786 (60%), Gaps = 22/786 (2%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ I+ IL S + +++ E ++P LT RGR++LI+ EN KY+N+ WNR
Sbjct: 93 YSQLGQEIVAILESSRFKYRTEIAPGKGDMPTLTDKDRGRFALIVYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPSIIHRISKI 1951
+LLDKYC EY V + F + N L ++KG L++ N ++ ++ P
Sbjct: 153 ELLDKYCVEYGVGIIGFFKANENSLLSA-QLKGFPLYLHSNLGLKDCSINPKSPLLYITR 211
Query: 1950 GNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE----------RAVVVRDKGLEDG 1804
N + DW +F+++ +E VL KS VV+D GL DG
Sbjct: 212 PNQVEKGDLPGEDWTVFQSNHSTYEPVLLAKTKSAESIPHLSVDAALHTTVVQDLGLHDG 271
Query: 1803 VERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDV 1624
++R++FG NL + K+ F+DA+ + G + S L+R+V VDIDD+FVG +GTR+ EDV
Sbjct: 272 IQRVLFGNNLNFWLHKLVFVDAVSFLTGKRLSLPLNRYVLVDIDDIFVGKEGTRMKVEDV 331
Query: 1623 RKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNH 1444
+ L TQ E R ++ NFTF LGFSG +F G D ED GD+ L+ ++F WFPHMW H
Sbjct: 332 KALYDTQMELRTHIPNFTFNLGFSGKFFHTGTDAEDEGDDLLLSYVKQFWWFPHMWSHMQ 391
Query: 1443 AHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSV 1267
H HN + L MA N+ FA + +P D YA+AP H GV+PVH QL+ AW+++W + V
Sbjct: 392 PHLFHNQSVLAEQMALNRKFAVDHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQIWGIKV 451
Query: 1266 TATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLF 1087
T+TEEYPH KPA R+GF+H GI +LPRQTCGL+THT ++EYP G ++ K I GG+LF
Sbjct: 452 TSTEEYPHLKPARYRRGFVHNGIMILPRQTCGLFTHTIFYNEYPGGPVELDKIINGGELF 511
Query: 1086 FTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFP 907
T+LLNPISIFMTH NY DRL LYTF+ L +F+ WTN+KL+ P+ + YFQ FP
Sbjct: 512 LTVLLNPISIFMTHLSNYGNDRLGLYTFKLLVQFLNTWTNLKLETLPPVQLAHKYFQIFP 571
Query: 906 DERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQN 727
+E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL +H + S N
Sbjct: 572 EEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLGMHSDLSSN 629
Query: 726 TPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPSAPKQAASL 559
P +FEE+QF+ GQNY KG++WYM FP S T FEKSA YFD+ AP++ A+L
Sbjct: 630 YPSSETFEEIQFYNGQNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSELAPRRVAAL 689
Query: 558 VPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSS--KKVRQRCIS 385
+P AKI+ IL NPA RAYSW+QH AH+DPVAI EVI + ++ RC+
Sbjct: 690 LPKAKIITILINPADRAYSWYQHQRAHDDPVAIKYTFQEVIKAGPEAPQRLRALQNRCLV 749
Query: 384 GGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFETYIRYSPS 208
G Y H+ +W+ HF Q++ +D L+ +P V+ ++ K+L + + + + P
Sbjct: 750 PGWYSTHIERWMNHFHANQILVLDGKLLRTEPANVMETVQKFLGVTNAMDYHKTLAFDPK 809
Query: 207 KGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTW 31
KGF C+LLD GKTKCLG+SKGRKYP+M + R L + N L K L K +PTW
Sbjct: 810 KGFWCQLLDGGKTKCLGKSKGRKYPDMDSDSRSFLMDYYRDHNIELSKLLYKMGQTLPTW 869
Query: 30 LEESVR 13
L E ++
Sbjct: 870 LREELQ 875
>gi|4505351|ref|NP_001534.1| N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 1; heparan
sulfate-N-deacetylase/N-sulfotransferase [Homo sapiens]
gi|1708322|sp|P52848|HSS1_HUMAN Heparan sulfate
N-deacetylase/N-sulfotransferase (N-HSST) (HSNST)
([Heparan sulfate]-glucosamine N-sulfotransferase)
(N-heparan sulfate sulfotransferase) (Glucosaminyl
N-deacetylase/N-sulfotransferase)
gi|2135335|pir||A57169 [heparan sulfate]-glucosamine
N-sulfotransferase (EC 2.8.2.8) - human
gi|976372|gb|AAA75281.1| heparan
sulfate-N-deacetylase/N-sulfotransferase
gi|1036797|gb|AAC27354.1| heparan N-deacetylase/N-sulfotransferase-1
[Homo sapiens]
Length = 882
Score = 679 bits (1751), Expect = 0.0
Identities = 353/794 (44%), Positives = 489/794 (61%), Gaps = 30/794 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ ++ IL S + +++ E ++P LT RGR++LII EN KY+N+ WNR
Sbjct: 93 YSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS----IIHR 1963
+LLDKYC Y V + F + N L ++KG L++ N ++ ++ P + R
Sbjct: 153 ELLDKYCVAYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCSINPKSPLLYVTR 211
Query: 1962 ISKIGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE--------------RAVVV 1828
S++ + DW +F+++ +E VL +S A VV
Sbjct: 212 PSEV----EKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVV 267
Query: 1827 RDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQG 1648
+D GL DG++R++FG NL + K+ F+DA+ + G + S LDR++ VDIDD+FVG +G
Sbjct: 268 QDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEG 327
Query: 1647 TRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWF 1468
TR+ EDV+ L TQ E R ++ NFTF LG+SG +F G + ED GD+ L+ ++F WF
Sbjct: 328 TRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWF 387
Query: 1467 PHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAW 1291
PHMW H H HN + L MA NK FA +P D YA+AP H GV+PVH QL+ AW
Sbjct: 388 PHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAW 447
Query: 1290 RKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQK 1111
++VW++ VT+TEEYPH KPA R+GFIH GI VLPRQTCGL+THT ++EYP G ++ K
Sbjct: 448 KQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDK 507
Query: 1110 SIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSS 931
I GG+LF T+LLNPISIFMTH NY DRL LYTF++L RF+ WTN++L+ P+ +
Sbjct: 508 IINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLA 567
Query: 930 QLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLS 751
Q YFQ F +E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL
Sbjct: 568 QKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLG 625
Query: 750 LHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPS 583
+HP+ S N P +FEE+QFF G NY KG++WYM FP S T FEKSA YFD+
Sbjct: 626 MHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEV 685
Query: 582 APKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSK-- 409
AP++AA+L+P AK++ IL NPA RAYSW+QH AH+DPVA+ EVI + SSK
Sbjct: 686 APRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLR 745
Query: 408 KVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFE 232
++ RC+ G Y H+ +WL + Q++ +D L+ +P V++ + K+L + +
Sbjct: 746 ALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYH 805
Query: 231 TYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK 55
+ + P KGF C+LL+ GKTKCLG+SKGRKYPEM + R L + N L K L K
Sbjct: 806 KTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYK 865
Query: 54 NRLKIPTWLEESVR 13
+PTWL E ++
Sbjct: 866 MGQTLPTWLREDLQ 879
>gi|12000419|ref|NP_072087.1| N-deacetylase/N-sulfotransferase
(heparin glucosaminyl) 4;
N-deacetylase/N-sulfotransferase 4 [Mus musculus]
gi|11344505|dbj|BAB18517.1| N-deacetylase/N-sulfotransferase 4 [Mus
musculus]
Length = 872
Score = 678 bits (1750), Expect = 0.0
Identities = 352/786 (44%), Positives = 489/786 (61%), Gaps = 22/786 (2%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ II IL S + Q++ ++P LT S +G+Y+LII EN KY++M WNR
Sbjct: 88 YSQLGQDIIAILESSRFQYQMVIAPGKGDIPPLTDSGKGKYTLIIYENILKYVSMDSWNR 147
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISK 1954
+LL+KYC EY V + F + N L ++KG L ++ N ++ +V P S + I+K
Sbjct: 148 ELLEKYCIEYSVSIIGFHKANENS-LPTTQLKGFPLNLFNNVALKDCSVNPQSPLLHITK 206
Query: 1953 IGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYER---------AVVVRDKGLEDG 1804
G + DW +F+ + ++ VL ++S A +++D GL DG
Sbjct: 207 -GPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQSEKSLSFLSSQTLYATIIQDLGLHDG 265
Query: 1803 VERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDV 1624
++R++FG NL + K+ F+DA+ + G + + +LDR++ VDIDD+FVG +GTR+ +DV
Sbjct: 266 IQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKDV 325
Query: 1623 RKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNH 1444
+ L+ TQ R V NFTF LGFSG ++ G + ED GD+ L+ + ++F WFPHMW H
Sbjct: 326 KALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDDLLLRSVDEFWWFPHMWSHMQ 385
Query: 1443 AHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSV 1267
H HN + L M NK FA +P++ YA+AP H GV+PVH QL+ AW+KVW + V
Sbjct: 386 PHLFHNESSLVEQMILNKEFALEHGIPINLGYAVAPHHSGVYPVHIQLYAAWKKVWGIQV 445
Query: 1266 TATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLF 1087
T+TEEYPH KPA RKGFIH I VLPRQTCGL+THT + EYP G ++ KSI+GG+LF
Sbjct: 446 TSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIKGGELF 505
Query: 1086 FTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFP 907
TILLNPISIFMTH NY DRL LYTF NL F+ WTN+KL+ P+ + YF+ FP
Sbjct: 506 LTILLNPISIFMTHLSNYGNDRLGLYTFVNLANFVHSWTNLKLQTLPPVQLAHKYFELFP 565
Query: 906 DERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQN 727
+++ PLW NPC D RH I C LP L+IGPQKTG+TAL FL +HP+ N
Sbjct: 566 EQKDPLWQNPCDDKRHKDIWSREKTC--DHLPKFLVIGPQKTGTTALYLFLLMHPSIISN 623
Query: 726 TPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPSAPKQAASL 559
P P +FEEVQFF G NY KG+EWYM FP+ S +T FEKSA YF + APK+A SL
Sbjct: 624 LPSPKTFEEVQFFNGNNYHKGIEWYMDFFPTPSNITSDFLFEKSANYFHSEEAPKRATSL 683
Query: 558 VPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSN--STSSKKVRQRCIS 385
VP AKI+ IL +P+ RAYSW+QH +HEDP A+ EVI + K +++RC+
Sbjct: 684 VPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVITTGHWAPPDLKTLQRRCLV 743
Query: 384 GGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL-PEFPFETYIRYSPS 208
G Y H+ +WL +FS Q++ +D +L+ P TV++ + K+L + P + + + + P
Sbjct: 744 PGWYAVHIERWLAYFSTSQLLIIDGQQLRSDPATVMDEVQKFLGVTPHYNYSEALTFDPQ 803
Query: 207 KGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTW 31
KGF C+LL+ GKTKCLG+SKGRKYP M R L + N L K L + +P+W
Sbjct: 804 KGFWCQLLEGGKTKCLGKSKGRKYPPMDSESRTFLSSYYRDHNVELSKLLHRLGQPLPSW 863
Query: 30 LEESVR 13
L + ++
Sbjct: 864 LRQELQ 869
>gi|841164|gb|AAA67765.1| heparan sulfate
N-deacetylase/N-sulfotransferase
Length = 882
Score = 676 bits (1745), Expect = 0.0
Identities = 352/794 (44%), Positives = 488/794 (61%), Gaps = 30/794 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ ++ IL S + +++ E ++P LT RGR++LII EN KY+N+ WNR
Sbjct: 93 YSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNR 152
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS----IIHR 1963
+LLDKYC Y V + F + N L ++KG L++ N ++ ++ P + R
Sbjct: 153 ELLDKYCVAYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCSINPKSPLLYVTR 211
Query: 1962 ISKIGNYRQFSSSDPADWILFETSEK-FESVLSGTVKSGYE--------------RAVVV 1828
S++ + DW +F+++ +E VL +S A VV
Sbjct: 212 PSEV----EKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVV 267
Query: 1827 RDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQG 1648
+D GL DG++R++FG NL + K+ F+DA+ + G + S LDR++ VDIDD+FVG +G
Sbjct: 268 QDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEG 327
Query: 1647 TRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWF 1468
TR+ EDV+ L TQ E R ++ NFTF LG+SG +F G + ED GD+ L+ ++F WF
Sbjct: 328 TRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWF 387
Query: 1467 PHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAW 1291
PHMW H H HN + L MA NK FA +P D YA+AP H GV+PVH QL+ AW
Sbjct: 388 PHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAW 447
Query: 1290 RKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQK 1111
++VW++ VT+TEEYPH KPA R+GFIH GI VLPRQTCGL+THT ++EYP G ++ K
Sbjct: 448 KQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDK 507
Query: 1110 SIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSS 931
I GG+LF T+LLNPISIFMTH NY DRL LYTF++L RF+ WTN++L+ P+ +
Sbjct: 508 IINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLA 567
Query: 930 QLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLS 751
Q YFQ F +E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL
Sbjct: 568 QKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLG 625
Query: 750 LHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPS 583
+HP+ S N P +FEE+QFF G NY KG++WYM FP S T FEKSA YFD+
Sbjct: 626 MHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFPIPSNTTSDFYFEKSANYFDSEV 685
Query: 582 APKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSS--K 409
AP+ AA+L+P AK++ IL NPA RAYSW+QH AH+DPVA+ EVI + SS +
Sbjct: 686 APRGAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSRLR 745
Query: 408 KVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFE 232
++ RC+ G Y H+ +WL + Q++ +D L+ +P V++ + K+L + +
Sbjct: 746 ALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYH 805
Query: 231 TYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRK 55
+ + P KGF C+LL+ GKTKCLG+SKGRKYPEM + R L + N L K L K
Sbjct: 806 KTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYK 865
Query: 54 NRLKIPTWLEESVR 13
+PTWL E ++
Sbjct: 866 MGQTLPTWLREDLQ 879
>gi|17736971|ref|NP_523946.1| CG8339-PA [Drosophila melanogaster]
gi|5802935|gb|AAD51842.1| heparan sulfate
N-deacetylase/N-sulfotransferase homolog [Drosophila
melanogaster]
gi|7295339|gb|AAF50658.1| CG8339-PA [Drosophila melanogaster]
Length = 1048
Score = 675 bits (1741), Expect = 0.0
Identities = 346/795 (43%), Positives = 499/795 (62%), Gaps = 36/795 (4%)
Frame = -1
Query: 2292 GKTIIQILNSQKLQFKAEAVSKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLDKY 2113
G+ I ++L ++++K E K+LPVLT +GRY +I+ EN KYLNM +WNR+LLDKY
Sbjct: 256 GRDIAELLVYNRIKYKIEVAGKSLPVLTNLDKGRYGVIVFENLDKYLNMDKWNRELLDKY 315
Query: 2112 CKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISKIGN--- 1945
C+EY V + F+S + L +++ L++ N R++ ++ P S + R+++ G
Sbjct: 316 CREYSVGIVGFVSPS-EETLVGAQLRDFPLFVNTNLRLRDASLNPLSSVLRLTRAGETAW 374
Query: 1944 -----------YRQFSSSDPADWILFETSEKFESVLSGTVKSGYERAVVVRDKGLEDGVE 1798
S+ +P +W T E + + G V+ V++D+G DG++
Sbjct: 375 GALPGDDWAVFQHNHSTYEPVEWAQRNTQE-YPADSVGQVQ--LPLTTVLQDRGQLDGIQ 431
Query: 1797 RIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRK 1618
R++FG +L + ++ FLDAL + Q S L+R + VDIDD+FVG +GTR+ +DVR
Sbjct: 432 RVLFGSSLRFWLHRLVFLDALSYLSHGQLSLNLERMILVDIDDIFVGEKGTRLRPDDVRA 491
Query: 1617 LISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAH 1438
LI+TQK V F F LGFSG Y+ +G E+ GD+FL++N ++F WF HMW+H H
Sbjct: 492 LIATQKNIAAMVPGFRFNLGFSGKYYHHGTREENLGDDFLLQNVQEFNWFSHMWKHQQPH 551
Query: 1437 EH-NFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTA 1261
+ N T L A M N FA + ++P D Y+I+P H GV+P HE L+ AW+KVWNV VT+
Sbjct: 552 LYDNLTLLMAEMHLNYAFAVDHNIPTDSGYSISPHHSGVYPAHELLYMAWKKVWNVKVTS 611
Query: 1260 TEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFT 1081
TEEYPH +PA R+GFIH I VLPRQTCGL+THT D YP G DK+ +SI+GG+LF T
Sbjct: 612 TEEYPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTMYIDRYPGGRDKLDESIQGGELFQT 671
Query: 1080 ILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDE 901
I+ NPI+IFMTH NY DRLALYTF+++ +F++CWTN+KL P+ +++YF+ P+E
Sbjct: 672 IVYNPINIFMTHMSNYGSDRLALYTFQSVIKFLQCWTNLKLASAPPVQLAEMYFRLHPEE 731
Query: 900 RTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTP 721
P+W NPC D RH I + NC SLP L+IGPQKTG+TAL +FLS+H + + N
Sbjct: 732 VDPVWGNPCDDVRHKKIWSKTKNC--DSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIA 789
Query: 720 VPGSFEEVQFFGGQNYLKGVEWYMSNFPSSS---------------TVTFEKSATYFDNP 586
P +FEEVQFF G NY +G++WYM FPS S FEKSATYFD
Sbjct: 790 SPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGE 849
Query: 585 SAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNST--SS 412
+ PK++ +L+PHAKIV IL +PA+RAYSW+QH +H D +A +VI S+S +
Sbjct: 850 AVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSFYQVITASDSAPRAL 909
Query: 411 KKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL-PEFPF 235
K +R RC++ G+Y HL WL ++ QQ+ +D ++L++ P V+N L ++L + P +
Sbjct: 910 KDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDY 969
Query: 234 ETYIRYSPSKGFHCRLLDGK-TKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLR 58
++RY KGF+C+ + K KCLG+SKGR+YP M E + L + + N+AL K L+
Sbjct: 970 SNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRYYLNHNTALVKLLK 1029
Query: 57 K-NRLKIPTWLEESV 16
K IP WL++ +
Sbjct: 1030 KLGSRPIPQWLKDDL 1044
>gi|12007650|ref|NP_072091.1| N-deacetylase/N-sulfotransferase
(heparan glucosaminyl) 4;
N-deacetylase/N-sulfotransferase 4 [Homo sapiens]
gi|11414892|dbj|BAB18535.1| N-deacetylase/N-sulfotransferase 4 [Homo
sapiens]
Length = 872
Score = 674 bits (1738), Expect = 0.0
Identities = 351/787 (44%), Positives = 487/787 (61%), Gaps = 23/787 (2%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ II IL S + Q+ ++P LT + +G+Y+L+I EN KY++M WNR
Sbjct: 88 YSQLGQDIIAILESSRFQYHMVIAPGKGDIPPLTDNGKGKYTLVIYENILKYVSMDSWNR 147
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISK 1954
+LL+KYC EY V + F + N L ++KG L ++ N ++ V P S + I+K
Sbjct: 148 ELLEKYCVEYSVSIIGFHKANENS-LPSTQLKGFPLNLFNNLALKDCFVNPQSPLLHITK 206
Query: 1953 IGNYRQFSSSDPADWILFE-----------TSEKFESVLSGTVKSGYERAVVVRDKGLED 1807
+ DW +F+ T + E LS ++ S A V++D GL D
Sbjct: 207 APKVEK-GPLPGEDWTIFQYNHSTYQPVLLTELQTEKSLS-SLSSKTLFATVIQDLGLHD 264
Query: 1806 GVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEED 1627
G++R++FG NL + K+ F+DA+ + G + + +LDR++ VDIDD+FVG +GTR+ +D
Sbjct: 265 GIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNVKD 324
Query: 1626 VRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHN 1447
V+ L+ TQ R V NFTF LGFSG ++ G + ED GD+ L+ + ++F WFPHMW H
Sbjct: 325 VKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDDLLLRSVDEFWWFPHMWSHM 384
Query: 1446 HAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVS 1270
H HN + L M NK FA +P++ YA+AP H GV+PVH QL+ AW+KVW +
Sbjct: 385 QPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSGVYPVHIQLYAAWKKVWGIQ 444
Query: 1269 VTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDL 1090
VT+TEEYPH KPA RKGFIH I VLPRQTCGL+THT + EYP G ++ KSI GG+L
Sbjct: 445 VTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKEYPGGPQELDKSIRGGEL 504
Query: 1089 FFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKF 910
F TILLNPISIFMTH NY DRL LYTF NL F++ WTN+KL+ P+ + YF+ F
Sbjct: 505 FLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNFVQSWTNLKLQTLPPVQLAHQYFELF 564
Query: 909 PDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQ 730
P+++ PLW NPC D RH I C LP L+IGPQKTG+TAL FL +HP+
Sbjct: 565 PEQKDPLWQNPCDDKRHKDIWSREKTC--DHLPKFLVIGPQKTGTTALYLFLLMHPSIIS 622
Query: 729 NTPVPGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPSAPKQAAS 562
N P P +FEEVQFF G NY KG++WYM FP+ S T FEKSA YF + AP++AAS
Sbjct: 623 NLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTTSDFLFEKSANYFHSEEAPRRAAS 682
Query: 561 LVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSS--KKVRQRCI 388
LVP AKI+ IL +P+ RAYSW+QH +HEDP A+ EVI + S K +++RC+
Sbjct: 683 LVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVISTGHWAPSDLKTLQRRCL 742
Query: 387 SGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL-PEFPFETYIRYSP 211
G Y H+ +WL +F+ Q++ +D +L+ P TV++ + K+L + P + + + + P
Sbjct: 743 VPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVMDEVQKFLGVTPRYNYSEALTFDP 802
Query: 210 SKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPT 34
KGF C+LL+ GKTKCLG+SKGRKYP M R L + N L K L + +P+
Sbjct: 803 QKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDHNVELSKLLHRLGQPLPS 862
Query: 33 WLEESVR 13
WL + ++
Sbjct: 863 WLRQELQ 869
>gi|4505353|ref|NP_003626.1| N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 2 [Homo sapiens]
gi|1708323|sp|P52849|HSS2_HUMAN Heparin sulfate
N-deacetylase/N-sulfotransferase (N-HSST) (N-heparin
sulfate sulfotransferase) (Glucosaminyl
N-deacetylase/N-sulfotransferase)
gi|1036799|gb|AAC27120.1| heparan N-deacetylase/N-sulfotransferase-2
[Homo sapiens]
gi|2792518|gb|AAB97086.1| heparan glucosaminyl
N-deacetylase/N-sulfotransferase-2 [Homo sapiens]
gi|23243099|gb|AAH35711.1| N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 2 [Homo sapiens]
Length = 883
Score = 668 bits (1723), Expect = 0.0
Identities = 346/801 (43%), Positives = 492/801 (61%), Gaps = 29/801 (3%)
Frame = -1
Query: 2328 VSVCKNRGHCQHGKTIIQILNSQKLQFKAEAVSK--NLPVLTTSRRGRYSLIIIENYYKY 2155
V V + Q G+ I+ IL S + ++ E ++P LT + GRY L+I EN KY
Sbjct: 87 VLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMPTLTDNTHGRYVLVIYENLLKY 146
Query: 2154 LNMAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS 1975
+N+ W+R+LLD+YC EY V + F + + L ++KG L++ N ++ V PS
Sbjct: 147 VNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSA-QLKGFPLFLHSNLGLRDYQVNPS 205
Query: 1974 IIHRISKIGNYRQFSSSDPA-----DWILFETSEK-FESVLSGTVKSGYERAV------- 1834
+ + + + S +P DW +F+++ +E VL +++ E AV
Sbjct: 206 -----APLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLLASLRPA-EPAVPGPVLRR 259
Query: 1833 -----VVRDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDD 1669
VV+D GL DG++R++FG L+ + K+ F+DA+ + G + LDR++ VDIDD
Sbjct: 260 ARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYLTGKRLCLDLDRYILVDIDD 319
Query: 1668 VFVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVEN 1489
+FVG +GTR+ DV L++TQ + R V NFTF LGFSG ++ G + ED GD+ L+++
Sbjct: 320 IFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDMLLKH 379
Query: 1488 AEKFVWFPHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVH 1312
++F WFPHMW H H HN + L M NK FA +P D YA+AP H GV+P+H
Sbjct: 380 RKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVYPIH 439
Query: 1311 EQLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPE 1132
QL+ AW+ VW + VT+TEEYPH +PA R+GFIH GI VLPRQTCGL+THT ++EYP
Sbjct: 440 TQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPG 499
Query: 1131 GFDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKW 952
G ++ +SI GG+LF T+LLNPISIFMTH NY DRL LYTFE+L RF++CWT ++L+
Sbjct: 500 GSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFESLVRFLQCWTRLRLQT 559
Query: 951 QDPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGST 772
P+ +Q YF+ FP ER+PLW NPC D RH I C + LP LI+GPQKTG+T
Sbjct: 560 LPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDR--LPKFLIVGPQKTGTT 617
Query: 771 ALASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFP----SSSTVTFEKSA 604
A+ FLSLHP + + P P +FEE+QFF NY KG++WYM FP +S+ FEKSA
Sbjct: 618 AIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNASTDFLFEKSA 677
Query: 603 TYFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSN 424
TYFD+ P++ A+L+P AKI+ +L NPA RAYSW+QH AH DPVA+ +VI S+
Sbjct: 678 TYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGDPVALNYTFYQVISASS 737
Query: 423 ST--SSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL 250
T + + ++ RC+ G Y HL +WL ++ Q++ VD EL+ P + S+ K+L +
Sbjct: 738 QTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESIQKFLGI 797
Query: 249 -PEFPFETYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSA 76
P + +R+ KGF C+ L+ GKT+CLG SKGR+YP+M R L F N
Sbjct: 798 TPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
Query: 75 LYKFLRKNRLKIPTWLEESVR 13
L K L + +P+WL E ++
Sbjct: 858 LSKLLSRLGQPVPSWLREELQ 878
>gi|13626042|ref|NP_112463.1| N-deacetylase/N-sulfotransferase
(heparan glucosaminyl) 3 [Mus musculus]
gi|11385420|gb|AAG34793.1| heparan sulfate
N-deacetylase/N-sulfotransferase 3 [Mus musculus]
Length = 873
Score = 667 bits (1720), Expect = 0.0
Identities = 343/783 (43%), Positives = 481/783 (60%), Gaps = 23/783 (2%)
Frame = -1
Query: 2292 GKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNRQLLD 2119
G+ II +L S + + E +LP LT + +G+Y LII EN KY+NM WNR LLD
Sbjct: 92 GQDIITMLESIRFHYHTEIAPGKGDLPALTDNVKGKYVLIIYENILKYINMDSWNRSLLD 151
Query: 2118 KYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISKIGNY 1942
KYC EY V + F + + L+ +++G + N ++ + P S + R++K
Sbjct: 152 KYCIEYGVGIIGFHKTSEKN-LQSFQVRGFPFSISGNLAVKDCCINPHSPLLRVTKSSKL 210
Query: 1941 RQFSSSDPADWILFETSEK-FESVLSGTVKSGYER----------AVVVRDKGLEDGVER 1795
+ S DW +F+ + ++ V+ VK+ A ++ D GL DG++R
Sbjct: 211 DR-GSLPGTDWTVFQINHSTYQPVIFAKVKTPENLSPPISKHAFYATIIHDLGLHDGIQR 269
Query: 1794 IIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEEDVRKL 1615
++FG NL + K+ F+DA+ + G + + +LDR++ VDIDD+FVG +GTR+ DV+ L
Sbjct: 270 VLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKAL 329
Query: 1614 ISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRHNHAHE 1435
+ TQ R + NFTF LGFSG ++ G + ED GD+ L+ + E+F WFPHMW H H
Sbjct: 330 LDTQNLLRTQITNFTFNLGFSGKFYHTGTEEEDEGDDCLLGSVEEFWWFPHMWSHMQPHL 389
Query: 1434 -HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNVSVTAT 1258
HN + L M NK FA +P D YA++P H GV+PVH QL+ AW+KVWN+ +T+T
Sbjct: 390 FHNESSLIEQMILNKKFALEHGIPTDMGYAVSPHHSGVYPVHVQLYEAWKKVWNIKITST 449
Query: 1257 EEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGDLFFTI 1078
EEYPH KPA R+GFIH I VLPRQTCGL+THT + EYP G ++ KSI GG+LFFT+
Sbjct: 450 EEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEYPGGPRELDKSIHGGELFFTV 509
Query: 1077 LLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQKFPDER 898
+LNPISIFMTH NY DRL LYTF NL F++ WTN++L+ P + YF+ FPD++
Sbjct: 510 VLNPISIFMTHLSNYGNDRLGLYTFVNLANFVQTWTNLRLQTLPPAQLAHKYFELFPDQK 569
Query: 897 TPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTSQNTPV 718
PLW NPC D RH I C + LP L+IGPQKTG+TAL FL +HP+ N+P
Sbjct: 570 DPLWQNPCDDKRHRDIWSKEKTCDR--LPKFLVIGPQKTGTTALCLFLIMHPSILSNSPS 627
Query: 717 PGSFEEVQFFGGQNYLKGVEWYMSNFPSSSTVT----FEKSATYFDNPSAPKQAASLVPH 550
P SFEEVQFF NY +G++WYM FP S VT FEKSA YF + APK+AASLVP
Sbjct: 628 PKSFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYFHSEDAPKRAASLVPK 687
Query: 549 AKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNST--SSKKVRQRCISGGR 376
AKI+ IL +P+ RAYSW+QH +HEDP A+ EVI + + +++RC+ G
Sbjct: 688 AKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPNAPWELRTLQKRCLVPGW 747
Query: 375 YVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL-PEFPFETYIRYSPSKGF 199
Y +H+ +WL +F Q++ +D L+ P TV++ + K+L + P + + + + KGF
Sbjct: 748 YANHIERWLVYFPPFQLLIIDGQHLRTTPATVMDEVQKFLGVSPHYNYSEALTFDSHKGF 807
Query: 198 HCRLL-DGKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIPTWLEE 22
C+LL +GKTKCLG+SKGRKYP M + R L + N L K L + +P+WL +
Sbjct: 808 WCQLLEEGKTKCLGKSKGRKYPPMDSDSRAFLSSYYRDHNVELSKLLHRLGQPLPSWLRQ 867
Query: 21 SVR 13
++
Sbjct: 868 ELQ 870
>gi|47215555|emb|CAG06285.1| unnamed protein product [Tetraodon
nigroviridis]
Length = 885
Score = 665 bits (1717), Expect = 0.0
Identities = 348/787 (44%), Positives = 489/787 (61%), Gaps = 24/787 (3%)
Frame = -1
Query: 2304 HCQHGKTIIQILNSQKLQFKAEAV--SKNLPVLTTSRRGRYSLIIIENYYKYLNMAQWNR 2131
+ Q G+ I+ IL + + +++ E ++P LT RGR++L+I EN KY+N+ WNR
Sbjct: 100 YSQLGQEIVAILEAGRFRYRTEISPGKGDMPTLTDKERGRFTLVIYENILKYVNLDAWNR 159
Query: 2130 QLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTP-SIIHRISK 1954
+LLDKYC EY V + F + N L ++KG L++ N ++ V P S + I++
Sbjct: 160 ELLDKYCVEYGVGIIGFFKANENSLLSA-QLKGFPLFLHSNLGLKDCTVNPKSPLLFITR 218
Query: 1953 IGNYRQFSSSDPAD-WILFETSEK-FESVLSGTVKSGYERAVV----------VRDKGLE 1810
G + P D W +F+++ +E VL +S A V V+D GL
Sbjct: 219 PG--QPLPGPLPGDDWTVFQSNHSTYEPVLLAKTQSAESVAPVAQNAALLPSVVQDLGLH 276
Query: 1809 DGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDVFVGAQGTRIVEE 1630
DG++R++FG NL + K+ F+DA+ + G + S +L+R+V VDIDD+FVG +GTR+
Sbjct: 277 DGIQRVLFGNNLGFWLHKLVFVDAVAFLTGKRLSLSLERYVLVDIDDIFVGKEGTRMKVP 336
Query: 1629 DVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENAEKFVWFPHMWRH 1450
DV+ L+ TQ+E R +V NFTF LGFSG +F G D ED GD+ L+ E+F WFPHMW H
Sbjct: 337 DVKALLETQRELRTHVPNFTFNLGFSGKFFHAGSDEEDLGDDLLLSYVEEFWWFPHMWSH 396
Query: 1449 NHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQLFRAWRKVWNV 1273
H HN + L M N+ FA +P + YA+AP H GV+PVH QL+ AW+KVW +
Sbjct: 397 MQPHLFHNQSVLAEQMLLNRKFAMEHGIPTNMGYAVAPHHSGVYPVHLQLYDAWKKVWGI 456
Query: 1272 SVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGFDKVQKSIEGGD 1093
VT+TEEYPH KPA R+GFIH+GI VLPRQTCGL+THT + +YP +++ K I GG+
Sbjct: 457 KVTSTEEYPHLKPARFRRGFIHSGISVLPRQTCGLFTHTIFYKDYPGSPNELDKLINGGE 516
Query: 1092 LFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQDPLTSSQLYFQK 913
LF T+LLNPISIFMTH NY DRL LYTF++L F++ WTN+KL+ P+ +Q YF
Sbjct: 517 LFLTVLLNPISIFMTHLSNYGNDRLGLYTFKSLMMFVRTWTNLKLQTLPPVQLAQKYFSL 576
Query: 912 FPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTALASFLSLHPNTS 733
FP E+ PLW +PC D RH I C + P LLIIGPQKTG+TAL FL +HP+ +
Sbjct: 577 FPSEKDPLWQDPCEDKRHKDIWSKEKTCDR--FPKLLIIGPQKTGTTALYLFLGMHPDLT 634
Query: 732 QNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFP----SSSTVTFEKSATYFDNPSAPKQAA 565
N P +FEE+QFF G NY +G++WYM FP +SS FEKSA YFD+ A ++AA
Sbjct: 635 SNYPSKETFEEIQFFNGHNYHRGIDWYMEYFPLPSNTSSDYYFEKSANYFDSEVAAQRAA 694
Query: 564 SLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNSTSSK--KVRQRC 391
+L+P AKI+ IL NPA RAYSW+QH AH+DPVA+ +VI + K ++ RC
Sbjct: 695 ALLPKAKIITILINPADRAYSWYQHQRAHDDPVALKYSFHDVITAGHDAPVKLRVLQNRC 754
Query: 390 ISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDLPE-FPFETYIRYS 214
+ G Y HL +WL ++ Q++ +D LK +P +V++ + K+L L + + +
Sbjct: 755 LVPGWYAVHLERWLNYYHSSQLLVLDGQMLKTEPASVMDKVQKFLSLTNIINYHKILAFD 814
Query: 213 PSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALYKFLRKNRLKIP 37
P KGF C+LL+ GKTKCLG+SKGR+YP+M + L + + N L K L + +P
Sbjct: 815 PKKGFWCQLLEGGKTKCLGKSKGRRYPDMNPESQAFLREYYRDHNIELSKLLYRMGQPLP 874
Query: 36 TWLEESV 16
+WL E +
Sbjct: 875 SWLREEL 881
>gi|7106357|ref|NP_034941.1| N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 2; mastocytoma
N-deacetylase/N-sulfotransferase; glucosaminyl
N-deacetylase/N-sulphotransferase 2; HEPARAN
N-SULFOTRANSFERASE 2; glucosaminyl
N-deacetylase/N-sulphotransferase-2; HEPARAN SULFATE
N-DEACETYLASE/N-SULFOTRANSFERASE 2; HEPARAN GLUCOSAMINYL
N-DEACETYLASE/N-SULFOTRANSFERASE 2 [Mus musculus]
gi|474431|emb|CAA53479.1| glucosaminyl N-deacetylase; glucosaminyl
N-sulfotransferase [Mus musculus]
Length = 882
Score = 663 bits (1710), Expect = 0.0
Identities = 341/799 (42%), Positives = 484/799 (59%), Gaps = 27/799 (3%)
Frame = -1
Query: 2328 VSVCKNRGHCQHGKTIIQILNSQKLQFKAEAVSK--NLPVLTTSRRGRYSLIIIENYYKY 2155
V V + Q G+ I+ IL S + ++ E V ++P LT GRY L+I EN KY
Sbjct: 87 VLVFVESAYSQLGQEIVAILESSRFRYSTELVPGRGDMPTLTDHTHGRYVLVIYENLLKY 146
Query: 2154 LNMAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS 1975
+N+ W+R+LLD+YC EY V + F ++ + L ++KG L++ N ++ V PS
Sbjct: 147 VNLDAWSRELLDRYCVEYGVGIIGFFRAREHSLLSA-QLKGFPLFLHSNLGLRDYQVNPS 205
Query: 1974 IIHRISKIGNYRQFSSSDPA-----DWILFETSEK-FESVL-----------SGTVKSGY 1846
+ + + + S +P DW +F+++ +E VL G V
Sbjct: 206 -----APLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLIASHRPAELSMPGPVLRRA 260
Query: 1845 ERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDV 1666
VV+D GL DG++R++FG L+ + K+ F+DA+ + G + LDR++ VDIDD+
Sbjct: 261 RLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLVFVDAVAYLTGKRLCLDLDRYILVDIDDI 320
Query: 1665 FVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENA 1486
FVG +GTR+ DV L++TQ + R V NFTF LGFSG ++ G + ED GD+ L+++
Sbjct: 321 FVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDMLLKHR 380
Query: 1485 EKFVWFPHMWRHNHAHEHNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHEQ 1306
+F WFPHMW H HN + L M NK FA +P D YA+AP H GV+P+H Q
Sbjct: 381 REFWWFPHMWSHMQPLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVYPIHSQ 440
Query: 1305 LFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEGF 1126
L+ AW+ VW + VT+TEEYPH +PA R+GFIH GI VLPRQTCGL+THT ++EYP G
Sbjct: 441 LYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGS 500
Query: 1125 DKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQD 946
++ +SI GG+LF T+LLNPIS+FMTH NY DRL LYTFE+L RF++CWT ++L+
Sbjct: 501 RELDRSIRGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFESLVRFLQCWTRLRLQTLP 560
Query: 945 PLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTAL 766
P+ +Q YF+ FP ER+PLW NPC D RH I C + LP LI+GPQKTG+TA+
Sbjct: 561 PVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDR--LPKFLIVGPQKTGTTAI 618
Query: 765 ASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFP----SSSTVTFEKSATY 598
FLSLHP + + P P +FEE+QFF G NY KG++WYM FP +S+ FEKSATY
Sbjct: 619 HFFLSLHPAVTSSFPSPSTFEEIQFFNGPNYHKGIDWYMDFFPVPSNASTDFLFEKSATY 678
Query: 597 FDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNST 418
FD+ P++ A+L+P AKI+ +L NPA RAYSW+QH AH DP+A+ +VI S+
Sbjct: 679 FDSEVVPRRGAALLPRAKIITVLINPADRAYSWYQHQRAHGDPIALNYTFYQVISASSQA 738
Query: 417 S--SKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL-P 247
+ ++ RC+ G Y HL +WL ++ Q++ +D EL++ P + + K+L + P
Sbjct: 739 PLLLRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIMDGQELRVNPAASMEIIQKFLGITP 798
Query: 246 EFPFETYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSALY 70
+ +R+ KGF C+ L+ GKT+CLG SKGR+YP+M R L F N L
Sbjct: 799 FLNYTRTLRFDEDKGFWCQGLEGGKTRCLGRSKGRRYPDMDMESRLFLTDFFRNHNLELS 858
Query: 69 KFLRKNRLKIPTWLEESVR 13
K L + P WL E ++
Sbjct: 859 KLLSRLGQPAPLWLREELQ 877
>gi|27807493|ref|NP_777202.1| N-deacetylase/N-sulfotransferase
(heparan glucosaminyl) 2 [Bos taurus]
gi|3885496|gb|AAC77921.1| heparin/heparan sulfate
N-acetylglucosaminyl N-deacetylase/N-sulfotransferase
[Bos taurus]
Length = 884
Score = 662 bits (1708), Expect = 0.0
Identities = 344/800 (43%), Positives = 488/800 (61%), Gaps = 28/800 (3%)
Frame = -1
Query: 2328 VSVCKNRGHCQHGKTIIQILNSQKLQFKAEAVSK--NLPVLTTSRRGRYSLIIIENYYKY 2155
V V + Q G+ I+ IL S + ++ E ++P LT RGRY L+I EN KY
Sbjct: 88 VLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMPTLTDHTRGRYVLVIYENLLKY 147
Query: 2154 LNMAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS 1975
+N+ W+R+LLD+YC EY V + F + + L ++KG L++ N ++ V P+
Sbjct: 148 VNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSA-QLKGFPLFLHSNLGLRDYQVNPT 206
Query: 1974 IIHRISKIGNYRQFSSSDPA-----DWILFETSEK-FESVLSGTVKSGY--------ERA 1837
+ + + + S +P DW +F+++ + +E VL G+++ RA
Sbjct: 207 -----APLLHLTRPSRLEPGPLPGDDWTIFQSNHRTYEPVLLGSLRPAEPPVPGPVARRA 261
Query: 1836 ---VVVRDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDV 1666
VV+D G+ DG++R++FG L+ + K+ F DA + G + LDR++ VDIDD+
Sbjct: 262 RLPTVVQDLGVHDGIQRVLFGHGLSFWLHKLVFRDAGGYLTGKGLLWDLDRYILVDIDDI 321
Query: 1665 FVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENA 1486
FVG +GTR+ DV L++TQ + R V NFTF LGFSG ++ G + ED GD+ L+ +
Sbjct: 322 FVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDMLLNHR 381
Query: 1485 EKFVWFPHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHE 1309
+F WFPHMW H H HN + L M NK FA +P D YA+AP H GV+P+H
Sbjct: 382 REFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVYPIHT 441
Query: 1308 QLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEG 1129
QL+ AW+ VW + VT+TEEYPH +PA R+GFIH GI VLPRQTCGL+THT ++EYP G
Sbjct: 442 QLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGG 501
Query: 1128 FDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQ 949
++ +SI GG+LF T+LLNPISIFMTH NY DRL LYTFE+L RF++CWT+++L+
Sbjct: 502 SRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFESLVRFLQCWTSLRLQTL 561
Query: 948 DPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTA 769
P+ + YF FP ER+PLW NPC D RH I C + LP LI+GPQKTG+TA
Sbjct: 562 PPVPLGRKYFDLFPQERSPLWQNPCDDKRHKDIWSKEKTCDR--LPKFLIVGPQKTGTTA 619
Query: 768 LASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFP----SSSTVTFEKSAT 601
+ FLSLHP + + P P +FEE+QFF G NY KG++WYM FP +S+ FEKSAT
Sbjct: 620 IHFFLSLHPAVTSSFPSPSTFEEIQFFNGPNYHKGIDWYMDFFPVPSNASTDFLFEKSAT 679
Query: 600 YFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNS 421
YFD+ P++ A+L+P AKI+ +L NPA RAYSW+QH AH DPVA+ +VI S+
Sbjct: 680 YFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGDPVALNYTFYQVITASSQ 739
Query: 420 --TSSKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL- 250
+ + ++ RC+ G Y HL +WL ++ Q++ VD EL+ P + + K+L +
Sbjct: 740 DPPALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMEIIQKFLGIT 799
Query: 249 PEFPFETYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSAL 73
P + +R+ KGF C+ L+ GKT+CLG+SKGRKYP+M R L F N L
Sbjct: 800 PFLNYTRTLRFDEDKGFWCQGLEGGKTRCLGKSKGRKYPDMDAESRLFLTDFFRNHNLEL 859
Query: 72 YKFLRKNRLKIPTWLEESVR 13
K L + +P+WL E ++
Sbjct: 860 SKLLSRLGQPVPSWLREELQ 879
>gi|1708324|sp|P52850|HSS2_MOUSE Heparin sulfate
N-deacetylase/N-sulfotransferase (N-HSST) (N-heparin
sulfate sulfotransferase) (Glucosaminyl
N-deacetylase/N-sulfotransferase)
gi|539823|pir||A49733 [heparan sulfate]-glucosamine
N-sulfotransferase (EC 2.8.2.8) - mouse
gi|457944|gb|AAC52137.1| glycosaminoglycan N-acetylglucosaminyl
N-deacetylase/N-sulfotransferase
gi|4322249|gb|AAD15979.1| heparan sulfate
N-deacetylase/N-sulfotransferase 2 [Mus musculus]
Length = 883
Score = 661 bits (1705), Expect = 0.0
Identities = 341/800 (42%), Positives = 484/800 (59%), Gaps = 28/800 (3%)
Frame = -1
Query: 2328 VSVCKNRGHCQHGKTIIQILNSQKLQFKAEAVSK--NLPVLTTSRRGRYSLIIIENYYKY 2155
V V + Q G+ I+ IL S + ++ E ++P LT GRY L+I EN KY
Sbjct: 87 VLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMPTLTDHTHGRYVLVIYENLLKY 146
Query: 2154 LNMAQWNRQLLDKYCKEYRVPMFSFMSSKPNDQLKRIKIKGSSLWMWQNQRIQRLAVTPS 1975
+N+ W+R+LLD+YC EY V + F ++ + L ++KG L++ N ++ V PS
Sbjct: 147 VNLDAWSRELLDRYCVEYGVGIIGFFRAREHSLLSA-QLKGFPLFLHSNLGLRDYQVNPS 205
Query: 1974 IIHRISKIGNYRQFSSSDPA-----DWILFETSEK-FESVL-----------SGTVKSGY 1846
+ + + + S +P DW +F+++ +E VL G V
Sbjct: 206 -----APLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLIASHRPAELSMPGPVLRRA 260
Query: 1845 ERAVVVRDKGLEDGVERIIFGRNLTDFQVKITFLDALWWAMGNQKSFTLDRFVQVDIDDV 1666
VV+D GL DG++R++FG L+ + K+ F+DA+ + G + LDR++ VDIDD+
Sbjct: 261 RLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLVFVDAVAYLTGKRLCLDLDRYILVDIDDI 320
Query: 1665 FVGAQGTRIVEEDVRKLISTQKEFRNYVQNFTFMLGFSGSYFRNGDDLEDRGDEFLVENA 1486
FVG +GTR+ DV L++TQ + R V NFTF LGFSG ++ G + ED GD+ L+++
Sbjct: 321 FVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDMLLKHR 380
Query: 1485 EKFVWFPHMWRHNHAHE-HNFTYLEAIMAQNKLFAQNMHLPVDYPYAIAPQHDGVFPVHE 1309
+F WFPHMW H H HN + L M NK FA +P D YA+AP H GV+P+H
Sbjct: 381 REFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVYPIHS 440
Query: 1308 QLFRAWRKVWNVSVTATEEYPHFKPATARKGFIHAGIHVLPRQTCGLYTHTQLFDEYPEG 1129
QL+ AW+ VW + VT+TEEYPH +PA R+GFIH GI VLPRQTCGL+THT ++EYP G
Sbjct: 441 QLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGG 500
Query: 1128 FDKVQKSIEGGDLFFTILLNPISIFMTHQQNYAYDRLALYTFENLFRFIKCWTNIKLKWQ 949
++ +SI GG+LF T+LLNPIS+FMTH NY DRL LYTFE+L RF++CWT ++L+
Sbjct: 501 SRELDRSIRGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFESLVRFLQCWTRLRLQTL 560
Query: 948 DPLTSSQLYFQKFPDERTPLWTNPCTDPRHHAILPPSINCTKKSLPDLLIIGPQKTGSTA 769
P+ +Q YF+ FP ER+PLW NPC D RH I C + LP LI+GPQKTG+TA
Sbjct: 561 PPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDR--LPKFLIVGPQKTGTTA 618
Query: 768 LASFLSLHPNTSQNTPVPGSFEEVQFFGGQNYLKGVEWYMSNFP----SSSTVTFEKSAT 601
+ FLSLHP + + P P +FEE+QFF G NY KG++WYM FP +S+ FEKSAT
Sbjct: 619 IHFFLSLHPAVTSSFPSPSTFEEIQFFNGPNYHKGIDWYMDFFPVPSNASTDFLFEKSAT 678
Query: 600 YFDNPSAPKQAASLVPHAKIVIILQNPAQRAYSWFQHILAHEDPVAITAGSLEVILDSNS 421
YFD+ P++ A+L+P AKI+ +L NPA RAYSW+QH AH DP+A+ +VI S+
Sbjct: 679 YFDSEVVPRRGAALLPRAKIITVLINPADRAYSWYQHQRAHGDPIALNYTFYQVISASSQ 738
Query: 420 TS--SKKVRQRCISGGRYVHHLTKWLEHFSLQQMIFVDSDELKMKPPTVLNSLSKWLDL- 250
+ ++ RC+ G Y HL +WL ++ Q++ +D EL++ P + + K+L +
Sbjct: 739 APLLLRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIMDGQELRVNPAASMEIIQKFLGIT 798
Query: 249 PEFPFETYIRYSPSKGFHCRLLD-GKTKCLGESKGRKYPEMPENLRRKLDKIFSLDNSAL 73
P + +R+ KGF C+ L+ GKT+CLG SKGR+YP+M R L F N L
Sbjct: 799 PFLNYTRTLRFDEDKGFWCQGLEGGKTRCLGRSKGRRYPDMDMESRLFLTDFFRNHNLEL 858
Query: 72 YKFLRKNRLKIPTWLEESVR 13
K L + P WL E ++
Sbjct: 859 SKLLSRLGQPAPLWLREELQ 878